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GSE58827: Dynamics of the Mouse Liver

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Results for Elf3

Z-value: 1.19

Motif logo

Transcription factors associated with Elf3

Gene Symbol Gene ID Gene Info
ENSMUSG00000003051.7 E74-like factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Elf3mm10_v2_chr1_-_135258449_1352584720.651.6e-05Click!

Activity profile of Elf3 motif

Sorted Z-values of Elf3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_142666816 15.26 ENSMUST00000105935.1
insulin-like growth factor 2
chr2_-_28084877 14.61 ENSMUST00000028179.8
ENSMUST00000117486.1
ENSMUST00000135472.1
ficolin B
chr8_+_72761868 13.21 ENSMUST00000058099.8
coagulation factor II (thrombin) receptor-like 3
chr14_+_80000292 9.53 ENSMUST00000088735.3
olfactomedin 4
chr17_+_29135056 8.64 ENSMUST00000087942.4
RAB44, member RAS oncogene family
chr11_+_87793470 7.66 ENSMUST00000020779.4
myeloperoxidase
chr16_+_17980565 7.48 ENSMUST00000075371.3
pre-B lymphocyte gene 2
chr11_+_87793722 7.33 ENSMUST00000143021.2
myeloperoxidase
chr11_+_115887601 7.14 ENSMUST00000167507.2
myosin XVB
chr12_+_109544498 6.99 ENSMUST00000126289.1
maternally expressed 3
chr5_-_43981757 6.92 ENSMUST00000061299.7
fibroblast growth factor binding protein 1
chrX_-_88760312 6.17 ENSMUST00000182943.1
predicted gene, 27000
chr15_-_103255433 5.77 ENSMUST00000075192.6
nuclear factor, erythroid derived 2
chr19_-_17356631 5.72 ENSMUST00000174236.1
glucosaminyl (N-acetyl) transferase 1, core 2
chr1_-_128592284 5.40 ENSMUST00000052172.6
ENSMUST00000142893.1
chemokine (C-X-C motif) receptor 4
chr17_+_25471564 5.19 ENSMUST00000025002.1
tektin 4
chr17_+_31208049 5.04 ENSMUST00000173776.1
ubiquitin associated and SH3 domain containing, A
chr7_+_24777172 4.81 ENSMUST00000038069.7
carcinoembryonic antigen-related cell adhesion molecule 10
chr5_+_115845229 4.62 ENSMUST00000137952.1
ENSMUST00000148245.1
citron
chr11_-_97996171 4.53 ENSMUST00000042971.9
ADP-ribosylation factor-like 5C
chr17_+_35049966 4.45 ENSMUST00000007257.9
chloride intracellular channel 1
chrX_-_135210672 4.25 ENSMUST00000033783.1
transcription elongation factor A (SII)-like 6
chr10_-_6980376 4.07 ENSMUST00000105617.1
interaction protein for cytohesin exchange factors 1
chr11_-_6520894 4.05 ENSMUST00000003459.3
myosin IG
chr10_+_79927039 4.03 ENSMUST00000019708.5
ENSMUST00000105377.1
AT rich interactive domain 3A (BRIGHT-like)
chr12_-_65172560 4.01 ENSMUST00000052201.8
MIS18 binding protein 1
chr1_-_193201435 3.92 ENSMUST00000043550.4
TRAF3 interacting protein 3
chr3_+_84666192 3.75 ENSMUST00000107682.1
transmembrane protein 154
chr3_+_103832562 3.71 ENSMUST00000062945.5
BCLl2-like 15
chr7_+_131032061 3.69 ENSMUST00000084509.3
deleted in malignant brain tumors 1
chr8_+_72189613 3.63 ENSMUST00000072097.6
hematopoietic SH2 domain containing
chr1_+_136467958 3.53 ENSMUST00000047817.6
kinesin family member 14
chr6_+_60944472 3.40 ENSMUST00000129603.1
multimerin 1
chr6_-_129917650 3.29 ENSMUST00000118060.1
killer cell lectin-like receptor, subfamily A, member 5
chrX_-_8090442 3.28 ENSMUST00000033505.6
Wiskott-Aldrich syndrome homolog (human)
chr7_-_3677509 3.28 ENSMUST00000038743.8
transmembrane channel-like gene family 4
chr2_+_164940742 3.17 ENSMUST00000137626.1
matrix metallopeptidase 9
chr10_-_30655859 3.11 ENSMUST00000092610.4
nuclear receptor coactivator 7
chr9_-_66919646 3.10 ENSMUST00000041139.7
RAB8B, member RAS oncogene family
chr1_-_87101590 3.08 ENSMUST00000113270.2
alkaline phosphatase, intestinal
chr1_+_135799833 3.08 ENSMUST00000148201.1
troponin I, skeletal, slow 1
chr1_+_170277376 3.07 ENSMUST00000179976.1
SH2 domain protein 1B1
chr2_+_131491958 3.07 ENSMUST00000110181.1
ENSMUST00000110180.1
spermine oxidase
chr3_-_15332285 2.98 ENSMUST00000108361.1
predicted gene 9733
chr3_-_51396528 2.95 ENSMUST00000038154.5
mitochondria localized glutamic acid rich protein
chr2_+_131491764 2.92 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
spermine oxidase
chrX_+_48146436 2.85 ENSMUST00000033427.6
SAM and SH3 domain containing 3
chr2_-_32083783 2.72 ENSMUST00000056406.6
family with sequence similarity 78, member A
chr17_+_71019503 2.68 ENSMUST00000024847.7
myomesin 1
chr7_+_30776394 2.67 ENSMUST00000041703.7
dermokine
chr2_+_101624734 2.61 ENSMUST00000111227.1
recombination activating gene 2
chr8_-_88636117 2.60 ENSMUST00000034087.7
sorting nexin 20
chr3_-_51396502 2.54 ENSMUST00000108046.1
mitochondria localized glutamic acid rich protein
chr3_-_51396716 2.51 ENSMUST00000141156.1
mitochondria localized glutamic acid rich protein
chr5_-_139736291 2.49 ENSMUST00000044642.10
MICAL-like 2
chr16_-_19883873 2.47 ENSMUST00000100083.3
RIKEN cDNA A930003A15 gene
chr1_-_133690100 2.47 ENSMUST00000169295.1
lymphocyte transmembrane adaptor 1
chr11_-_17008647 2.44 ENSMUST00000102881.3
pleckstrin
chr4_-_63403330 2.42 ENSMUST00000035724.4
AT-hook transcription factor
chr6_+_29694204 2.40 ENSMUST00000046750.7
ENSMUST00000115250.3
tetraspanin 33
chr1_+_166130467 2.37 ENSMUST00000166860.1
glycoprotein A33 (transmembrane)
chr8_+_88294204 2.37 ENSMUST00000098521.2
adenylate cyclase 7
chr5_-_34637107 2.36 ENSMUST00000124668.1
ENSMUST00000001109.4
ENSMUST00000155577.1
ENSMUST00000114329.1
major facilitator superfamily domain containing 10
chr3_-_89418287 2.34 ENSMUST00000029679.3
CDC28 protein kinase 1b
chr13_+_44729535 2.32 ENSMUST00000174068.1
jumonji, AT rich interactive domain 2
chr5_-_34637203 2.29 ENSMUST00000114331.3
major facilitator superfamily domain containing 10
chr16_+_10170228 2.28 ENSMUST00000044103.5
ribosomal protein L39-like
chr4_+_127172866 2.27 ENSMUST00000106094.2
discs, large (Drosophila) homolog-associated protein 3
chr1_+_166130238 2.21 ENSMUST00000060833.7
ENSMUST00000166159.1
glycoprotein A33 (transmembrane)
chr4_-_156255327 2.20 ENSMUST00000179919.1
sterile alpha motif domain containing 11
chr8_-_65129317 2.18 ENSMUST00000098713.3
cDNA sequence BC030870
chr7_+_30291659 2.18 ENSMUST00000014065.8
ENSMUST00000150892.1
ENSMUST00000126216.1
CAP-GLY domain containing linker protein 3
chr15_-_66812593 2.16 ENSMUST00000100572.3
src-like adaptor
chr16_-_3718105 2.10 ENSMUST00000023180.7
ENSMUST00000100222.2
Mediterranean fever
chr19_-_50678642 2.08 ENSMUST00000072685.6
ENSMUST00000164039.2
VPS10 domain receptor protein SORCS 1
chr15_-_97908261 2.08 ENSMUST00000023119.8
vitamin D receptor
chr1_+_51987139 2.08 ENSMUST00000168302.1
signal transducer and activator of transcription 4
chr14_+_31208309 2.05 ENSMUST00000169169.1
troponin C, cardiac/slow skeletal
chr4_-_11965699 2.05 ENSMUST00000108301.1
ENSMUST00000095144.3
ENSMUST00000108302.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr5_+_110330697 2.01 ENSMUST00000112481.1
polymerase (DNA directed), epsilon
chr6_-_78378851 2.00 ENSMUST00000089667.1
ENSMUST00000167492.1
regenerating islet-derived 3 delta
chr16_+_19760232 1.99 ENSMUST00000079780.3
ENSMUST00000164397.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr13_+_44729794 1.98 ENSMUST00000172830.1
jumonji, AT rich interactive domain 2
chr11_+_11489266 1.97 ENSMUST00000109678.1
RIKEN cDNA 4930415F15 gene
chr19_+_11404735 1.94 ENSMUST00000153546.1
membrane-spanning 4-domains, subfamily A, member 4C
chr7_-_45238794 1.94 ENSMUST00000098461.1
ENSMUST00000107797.1
CD37 antigen
chr3_-_52104891 1.93 ENSMUST00000121440.1
mastermind like 3 (Drosophila)
chr1_+_40324570 1.93 ENSMUST00000095020.3
interleukin 1 receptor-like 2
chr11_+_32533290 1.93 ENSMUST00000102821.3
serine/threonine kinase 10
chr12_-_8539545 1.92 ENSMUST00000095863.3
ENSMUST00000165657.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 15
chr13_+_13437602 1.84 ENSMUST00000005532.7
nidogen 1
chr15_+_79516396 1.84 ENSMUST00000010974.7
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr5_-_131538687 1.80 ENSMUST00000161374.1
autism susceptibility candidate 2
chr10_+_127323700 1.79 ENSMUST00000069548.5
Rho GTPase activating protein 9
chr17_+_32403006 1.79 ENSMUST00000065921.5
RIKEN cDNA A530088E08 gene
chr11_-_117779605 1.78 ENSMUST00000143406.1
transmembrane channel-like gene family 6
chr1_-_156474249 1.77 ENSMUST00000051396.6
sterol O-acyltransferase 1
chr10_-_117292863 1.74 ENSMUST00000092162.5
lysozyme 1
chr7_-_104950441 1.73 ENSMUST00000179862.1
predicted pseudogene 5900
chr3_-_105932664 1.72 ENSMUST00000098758.2
RIKEN cDNA I830077J02 gene
chr7_+_29983948 1.72 ENSMUST00000148442.1
zinc finger protein 568
chr9_-_120068263 1.72 ENSMUST00000064165.3
ENSMUST00000177637.1
chemokine (C-X3-C) receptor 1
chr14_-_20496780 1.68 ENSMUST00000022353.3
MSS51 mitochondrial translational activator
chr1_+_75382114 1.67 ENSMUST00000113590.1
ENSMUST00000148515.1
SPEG complex locus
chr3_+_95160449 1.66 ENSMUST00000090823.1
ENSMUST00000090821.3
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr10_+_79988584 1.66 ENSMUST00000004784.4
ENSMUST00000105374.1
calponin 2
chrX_+_9350599 1.64 ENSMUST00000073949.2
predicted gene 14501
chr4_-_156228540 1.64 ENSMUST00000105571.2
pleckstrin homology domain containing, family N member 1
chr17_-_47834682 1.64 ENSMUST00000066368.6
MyoD family inhibitor
chr10_-_23787195 1.60 ENSMUST00000073926.6
ribosomal protein S12
chr6_-_16898441 1.60 ENSMUST00000031533.7
transcription factor EC
chr1_-_136230289 1.59 ENSMUST00000150163.1
ENSMUST00000144464.1
RIKEN cDNA 5730559C18 gene
chrX_+_164139321 1.56 ENSMUST00000112271.3
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr7_+_30763750 1.55 ENSMUST00000165887.1
ENSMUST00000085691.4
ENSMUST00000085688.4
ENSMUST00000054427.6
dermokine
chr16_+_19760195 1.55 ENSMUST00000121344.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr9_-_119209096 1.54 ENSMUST00000084797.4
solute carrier family 22 (organic cation transporter), member 13
chr15_-_9529868 1.54 ENSMUST00000003981.4
interleukin 7 receptor
chr19_-_50678485 1.53 ENSMUST00000111756.3
VPS10 domain receptor protein SORCS 1
chrX_+_11302432 1.53 ENSMUST00000179428.1
predicted gene 14474
chr12_-_112860886 1.52 ENSMUST00000021729.7
G protein-coupled receptor 132
chr7_+_130865835 1.48 ENSMUST00000075181.4
ENSMUST00000048180.5
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr3_+_88376023 1.41 ENSMUST00000179946.1
predicted gene, 21956
chr16_+_92485705 1.36 ENSMUST00000162181.1
chloride intracellular channel 6
chr6_+_119175247 1.35 ENSMUST00000112777.2
ENSMUST00000073909.5
DCP1 decapping enzyme homolog B (S. cerevisiae)
chr3_+_129881149 1.34 ENSMUST00000061165.7
phospholipase A2, group XIIA
chr6_-_145434925 1.34 ENSMUST00000111708.2
intermediate filament tail domain containing 1
chr5_-_123879992 1.34 ENSMUST00000164267.1
G protein-coupled receptor 81
chr7_-_125491397 1.33 ENSMUST00000138616.1
non-SMC element 1 homolog (S. cerevisiae)
chr8_-_119605199 1.33 ENSMUST00000093099.6
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, C
chr16_+_92498122 1.30 ENSMUST00000023670.3
chloride intracellular channel 6
chr3_+_87376381 1.28 ENSMUST00000163661.1
ENSMUST00000072480.2
ENSMUST00000167200.1
Fc receptor-like 1
chr8_+_75214502 1.28 ENSMUST00000132133.1
RASD family, member 2
chrX_+_73123068 1.26 ENSMUST00000179117.1
predicted gene 14685
chr7_+_142434977 1.21 ENSMUST00000118276.1
ENSMUST00000105976.1
ENSMUST00000097939.2
synaptotagmin VIII
chr3_+_90603767 1.20 ENSMUST00000001046.5
ENSMUST00000107330.1
S100 calcium binding protein A4
chr5_+_33983437 1.20 ENSMUST00000114384.1
ENSMUST00000094869.5
ENSMUST00000114383.1
predicted gene 1673
chr10_-_62231208 1.19 ENSMUST00000047883.9
tetraspanin 15
chr6_-_128300738 1.19 ENSMUST00000143004.1
ENSMUST00000006311.6
ENSMUST00000112157.2
ENSMUST00000133118.1
TEA domain family member 4
chr11_-_76571527 1.18 ENSMUST00000072740.6
active BCR-related gene
chr5_+_33983534 1.18 ENSMUST00000114382.1
predicted gene 1673
chr8_-_82403203 1.18 ENSMUST00000034148.6
interleukin 15
chrX_+_152781986 1.18 ENSMUST00000026383.3
G protein-coupled receptor 143
chr3_-_103791075 1.17 ENSMUST00000106845.2
ENSMUST00000029438.8
ENSMUST00000121324.1
homeodomain interacting protein kinase 1
chr1_+_170308802 1.13 ENSMUST00000056991.5
RIKEN cDNA 1700015E13 gene
chr1_-_161876656 1.12 ENSMUST00000048377.5
SUN domain containing ossification factor
chr11_-_103344651 1.10 ENSMUST00000041385.7
Rho GTPase activating protein 27
chr5_+_108065742 1.08 ENSMUST00000081567.4
ENSMUST00000170319.1
ENSMUST00000112626.1
metal response element binding transcription factor 2
chr7_+_101361250 1.07 ENSMUST00000137384.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr17_-_17883920 1.07 ENSMUST00000061516.7
formyl peptide receptor 1
chr7_-_45759527 1.06 ENSMUST00000075571.7
sulfotransferase family, cytosolic, 2B, member 1
chr2_+_165055668 1.06 ENSMUST00000081310.4
ENSMUST00000140951.1
CD40 antigen
chr7_+_102065713 1.05 ENSMUST00000094129.2
ENSMUST00000094130.2
ENSMUST00000084843.3
transient receptor potential cation channel, subfamily C, member 2
chr4_-_83021102 1.04 ENSMUST00000071708.5
Fras1 related extracellular matrix protein 1
chr7_-_125491586 1.04 ENSMUST00000033006.7
non-SMC element 1 homolog (S. cerevisiae)
chr2_-_119229885 1.03 ENSMUST00000076084.5
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr9_-_43116514 1.03 ENSMUST00000061833.4
transmembrane protein 136
chr14_+_53709902 1.03 ENSMUST00000103638.4
T cell receptor alpha variable 6-7-DV9
chr10_+_7667503 1.02 ENSMUST00000040135.8
nucleoporin 43
chr17_-_25880236 1.00 ENSMUST00000176696.1
ENSMUST00000095487.5
WAP, FS, Ig, KU, and NTR-containing protein 1
chr7_+_127876796 1.00 ENSMUST00000131000.1
zinc finger protein 646
chr11_-_94782500 1.00 ENSMUST00000162809.2
transmembrane protein 92
chr11_-_121118677 0.97 ENSMUST00000039146.3
testis expressed gene 19.2
chr14_-_70524068 0.97 ENSMUST00000022692.3
surfactant associated protein C
chr9_-_32928928 0.97 ENSMUST00000185169.1
RP24-308I2.1
chr1_-_75264195 0.94 ENSMUST00000027404.5
protein tyrosine phosphatase, receptor type, N
chr14_-_70175397 0.89 ENSMUST00000143393.1
PDZ and LIM domain 2
chr7_-_119793958 0.89 ENSMUST00000106523.1
ENSMUST00000063902.7
ENSMUST00000150844.1
exoribonuclease 2
chr11_+_77765588 0.88 ENSMUST00000164315.1
myosin XVIIIA
chrX_+_9283764 0.87 ENSMUST00000177926.1
RIKEN cDNA 1700012L04 gene
chr9_-_76567092 0.87 ENSMUST00000183437.1
family with sequence similarity 83, member B
chr16_+_18498768 0.86 ENSMUST00000167778.1
ENSMUST00000139625.1
ENSMUST00000149035.1
ENSMUST00000090086.4
ENSMUST00000115601.1
ENSMUST00000147739.1
ENSMUST00000146673.1
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
predicted gene 16314
chr17_+_5975740 0.86 ENSMUST00000115790.1
synaptojanin 2
chrX_-_163761323 0.85 ENSMUST00000059320.2
ring finger protein 138, retrogene 1
chr11_+_111066154 0.83 ENSMUST00000042970.2
potassium inwardly-rectifying channel, subfamily J, member 2
chr8_+_66386292 0.83 ENSMUST00000039540.5
ENSMUST00000110253.2
membrane-associated ring finger (C3HC4) 1
chr4_-_136053343 0.82 ENSMUST00000102536.4
ribosomal protein L11
chr5_-_77310049 0.81 ENSMUST00000047860.8
nitric oxide associated 1
chr7_+_119794102 0.81 ENSMUST00000084644.2
RIKEN cDNA 2610020H08 gene
chr15_-_36608959 0.80 ENSMUST00000001809.8
poly(A) binding protein, cytoplasmic 1
chr17_-_13052280 0.78 ENSMUST00000091648.2
G protein-coupled receptor 31, D17Leh66b region
chr4_+_86930691 0.77 ENSMUST00000164590.1
alkaline ceramidase 2
chr6_+_115134899 0.75 ENSMUST00000009538.5
ENSMUST00000169345.1
synapsin II
chr7_+_119793987 0.75 ENSMUST00000033218.8
ENSMUST00000106520.1
RIKEN cDNA 2610020H08 gene
chr1_+_170232749 0.71 ENSMUST00000162752.1
SH2 domain protein 1B2
chr18_-_37638719 0.71 ENSMUST00000058635.2
solute carrier family 25 (mitochondrial carrier, ornithine transporter) member 2
chr19_-_5912771 0.70 ENSMUST00000118623.1
D4, zinc and double PHD fingers family 2
chr7_-_127208423 0.70 ENSMUST00000120705.1
TBC1 domain family, member 10b
chr13_+_111867931 0.70 ENSMUST00000128198.1
predicted gene 15326
chr2_+_165055625 0.69 ENSMUST00000017799.5
ENSMUST00000073707.2
CD40 antigen
chr8_+_104340594 0.69 ENSMUST00000034343.4
CKLF-like MARVEL transmembrane domain containing 3
chr7_+_102065485 0.69 ENSMUST00000106950.1
ENSMUST00000146450.1
transient receptor potential cation channel, subfamily C, member 2
chr7_+_101896817 0.68 ENSMUST00000143835.1
anaphase prompoting complex C subunit 15
chr5_+_77310147 0.67 ENSMUST00000031167.5
polymerase (RNA) II (DNA directed) polypeptide B
chr5_+_17574268 0.66 ENSMUST00000030568.7
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr10_-_117238665 0.66 ENSMUST00000020392.4
RIKEN cDNA 9530003J23 gene
chr12_-_80260356 0.64 ENSMUST00000021554.8
actinin, alpha 1
chr3_+_98222148 0.64 ENSMUST00000029469.4
regenerating islet-derived family, member 4
chr12_+_83950608 0.64 ENSMUST00000053744.7
RIKEN cDNA 2410016O06 gene
chr11_+_98383811 0.63 ENSMUST00000008021.2
titin-cap
chr12_+_65075582 0.63 ENSMUST00000058889.4
Fanconi anemia, complementation group M

Network of associatons between targets according to the STRING database.

First level regulatory network of Elf3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 15.0 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
3.7 14.6 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
1.9 15.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.3 5.4 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
1.2 3.5 GO:0033624 negative regulation of integrin activation(GO:0033624)
1.1 3.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
1.1 4.2 GO:1903575 cornified envelope assembly(GO:1903575)
1.0 5.2 GO:0080154 regulation of fertilization(GO:0080154)
1.0 8.0 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
1.0 15.6 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.9 4.7 GO:0042891 antibiotic transport(GO:0042891)
0.9 2.6 GO:0002358 B cell homeostatic proliferation(GO:0002358)
0.9 6.9 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.9 6.0 GO:0046208 spermine catabolic process(GO:0046208)
0.8 4.0 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.8 3.1 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.7 3.6 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.7 2.1 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.7 2.0 GO:0045004 DNA replication proofreading(GO:0045004)
0.6 1.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.6 1.2 GO:0035723 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.5 3.3 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.5 2.1 GO:0071608 macrophage inflammatory protein-1 alpha production(GO:0071608)
0.5 2.1 GO:0038183 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) bile acid signaling pathway(GO:0038183)
0.5 5.8 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.4 5.7 GO:0060352 cell adhesion molecule production(GO:0060352)
0.4 1.6 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827) positive regulation of gap junction assembly(GO:1903598)
0.4 3.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.3 1.7 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.3 1.7 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.3 2.2 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.3 4.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 0.8 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.3 0.8 GO:0048866 endodermal cell fate determination(GO:0007493) stem cell fate specification(GO:0048866) regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796) regulation of cardiac cell fate specification(GO:2000043)
0.3 1.8 GO:0006621 protein retention in ER lumen(GO:0006621)
0.3 3.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.3 0.8 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.2 1.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.2 0.7 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.2 1.2 GO:0060313 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.2 7.0 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 0.9 GO:1903028 asymmetric Golgi ribbon formation(GO:0090164) regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.2 5.0 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.2 1.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.2 1.1 GO:0000103 sulfate assimilation(GO:0000103)
0.2 3.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 4.6 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.2 1.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.2 3.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 1.9 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.2 3.1 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.2 1.5 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.2 1.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.2 1.8 GO:0042983 very-low-density lipoprotein particle assembly(GO:0034379) amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.2 1.9 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 1.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 1.2 GO:1903056 regulation of melanosome organization(GO:1903056)
0.2 2.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.2 3.3 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.2 0.8 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.2 0.8 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.2 0.8 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 2.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 2.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 1.8 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 2.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 2.0 GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872)
0.1 8.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.1 GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process(GO:0032805)
0.1 0.5 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.1 0.6 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 0.4 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.6 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 7.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.3 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.1 1.5 GO:0015747 urate transport(GO:0015747)
0.1 0.6 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.1 0.6 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.3 GO:0036363 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.7 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.7 GO:0003350 pulmonary myocardium development(GO:0003350) dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 2.4 GO:0006301 postreplication repair(GO:0006301)
0.1 0.3 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.3 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 1.2 GO:0061072 iris morphogenesis(GO:0061072)
0.1 1.2 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 2.0 GO:0001553 luteinization(GO:0001553)
0.1 0.5 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 1.7 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.1 7.5 GO:0042100 B cell proliferation(GO:0042100)
0.1 0.2 GO:0040010 positive regulation of growth rate(GO:0040010)
0.1 0.4 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 1.6 GO:0009950 dorsal/ventral axis specification(GO:0009950) trophoblast giant cell differentiation(GO:0060707)
0.1 0.5 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.1 0.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.2 GO:0046370 fructose biosynthetic process(GO:0046370)
0.1 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 2.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.6 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 2.5 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 1.5 GO:0007340 acrosome reaction(GO:0007340)
0.0 2.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.9 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 1.9 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 1.1 GO:0044253 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0 0.8 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 3.5 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 1.5 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.2 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.0 1.0 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 1.1 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.4 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.4 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 0.9 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.8 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.3 GO:2001269 negative regulation by host of viral transcription(GO:0043922) positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 1.7 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 1.0 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.4 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.0 0.1 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.6 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0001771 immunological synapse formation(GO:0001771)
0.0 1.2 GO:0090630 activation of GTPase activity(GO:0090630)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 14.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
1.0 9.5 GO:0042581 specific granule(GO:0042581)
0.9 15.0 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.4 2.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.4 2.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.3 2.1 GO:0001651 dense fibrillar component(GO:0001651)
0.3 2.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.3 2.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.3 3.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.3 1.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.3 4.0 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.3 1.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.3 8.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.3 3.1 GO:0005861 troponin complex(GO:0005861)
0.2 0.6 GO:0032127 dense core granule membrane(GO:0032127)
0.2 3.1 GO:0051286 cell tip(GO:0051286)
0.2 5.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 1.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 5.2 GO:0097228 sperm principal piece(GO:0097228)
0.1 4.0 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.8 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 2.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 8.3 GO:0031985 Golgi cisterna(GO:0031985)
0.1 7.0 GO:0034707 chloride channel complex(GO:0034707)
0.1 3.5 GO:0051233 spindle midzone(GO:0051233)
0.1 5.6 GO:0031901 early endosome membrane(GO:0031901)
0.1 2.7 GO:0032982 muscle myosin complex(GO:0005859) myosin filament(GO:0032982)
0.1 1.0 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 2.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.0 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 1.8 GO:0005605 basal lamina(GO:0005605)
0.1 1.8 GO:0043196 varicosity(GO:0043196)
0.1 0.9 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 5.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.3 GO:0031523 Myb complex(GO:0031523)
0.1 1.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 1.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.7 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.4 GO:0016460 myosin II complex(GO:0016460)
0.0 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 8.1 GO:0005903 brush border(GO:0005903)
0.0 2.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 6.5 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 5.7 GO:0005769 early endosome(GO:0005769)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 0.6 GO:0001741 XY body(GO:0001741)
0.0 2.1 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 5.9 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.8 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 1.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 2.1 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 2.6 GO:0012506 vesicle membrane(GO:0012506)
0.0 0.6 GO:0005844 polysome(GO:0005844)
0.0 1.8 GO:0005875 microtubule associated complex(GO:0005875)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 13.2 GO:0015057 thrombin receptor activity(GO:0015057)
2.0 6.0 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
1.9 5.7 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
1.6 14.6 GO:0033691 sialic acid binding(GO:0033691)
1.2 3.5 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.9 4.7 GO:0042895 antibiotic transporter activity(GO:0042895)
0.9 2.7 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.8 5.4 GO:0032027 myosin light chain binding(GO:0032027)
0.7 2.1 GO:1902271 lithocholic acid binding(GO:1902121) D3 vitamins binding(GO:1902271)
0.6 1.9 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.6 2.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.5 2.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.5 1.8 GO:0046923 ER retention sequence binding(GO:0046923)
0.4 15.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.4 3.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.4 3.1 GO:0030911 TPR domain binding(GO:0030911)
0.4 2.2 GO:0042731 PH domain binding(GO:0042731)
0.4 2.2 GO:0097001 ceramide binding(GO:0097001)
0.3 1.7 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.3 10.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.3 2.1 GO:0031013 troponin I binding(GO:0031013)
0.3 2.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.3 0.8 GO:0071633 dihydroceramidase activity(GO:0071633)
0.3 2.0 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.2 15.0 GO:0004601 peroxidase activity(GO:0004601)
0.2 1.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 0.9 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 6.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 10.0 GO:0050699 WW domain binding(GO:0050699)
0.2 0.4 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.2 1.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 1.1 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.1 2.1 GO:0003796 lysozyme activity(GO:0003796)
0.1 2.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 1.2 GO:0035240 dopamine binding(GO:0035240)
0.1 0.7 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 2.7 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.1 0.6 GO:0051373 FATZ binding(GO:0051373)
0.1 5.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 2.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 3.2 GO:0001968 fibronectin binding(GO:0001968)
0.1 3.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 3.3 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.6 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.8 GO:0043237 laminin-1 binding(GO:0043237)
0.1 1.4 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 4.3 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.8 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.8 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 3.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 3.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 6.0 GO:0097110 scaffold protein binding(GO:0097110)
0.1 1.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.7 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 2.5 GO:0042805 actinin binding(GO:0042805)
0.1 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.9 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 0.6 GO:0050700 CARD domain binding(GO:0050700)
0.1 1.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.2 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.1 0.1 GO:0034617 nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.1 0.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 2.5 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 3.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 1.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.0 1.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.6 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.0 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 1.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.1 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.9 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.8 GO:0042287 MHC protein binding(GO:0042287)
0.0 2.4 GO:0005254 chloride channel activity(GO:0005254)
0.0 7.3 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0052851 ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 2.4 GO:0005525 GTP binding(GO:0005525)
0.0 1.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 5.9 GO:0045296 cadherin binding(GO:0045296)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 1.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.3 17.1 PID IL23 PATHWAY IL23-mediated signaling events
0.2 9.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 15.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 4.7 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.8 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 2.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 4.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 2.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.6 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.8 PID ARF 3PATHWAY Arf1 pathway
0.0 1.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 3.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 3.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 6.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 2.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.3 PID P73PATHWAY p73 transcription factor network
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.4 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.7 15.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4 6.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 11.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.2 2.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 2.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 2.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 8.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 2.1 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 3.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 5.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 4.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 2.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 3.3 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 1.0 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.7 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 2.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 4.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.0 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 1.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 3.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade