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GSE58827: Dynamics of the Mouse Liver

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Results for Etv6

Z-value: 1.25

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Transcription factors associated with Etv6

Gene Symbol Gene ID Gene Info
Etv6
ENSMUSG00000030199.10 ets variant 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Etv6mm10_v2_chr6_+_134035691_134035717-0.812.3e-09Click!

Activity profile of Etv6 motif

Sorted Z-values of Etv6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_155517948 3.36 ENSMUST00000029135.8
ENSMUST00000065973.2
ENSMUST00000103142.5
Acss2
acyl-CoA synthetase short-chain family member 2
chr3_-_89764581 3.06 ENSMUST00000029562.3
Chrnb2
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr2_-_130424242 2.92 ENSMUST00000089581.4
Pced1a
PC-esterase domain containing 1A
chr1_+_58586381 2.61 ENSMUST00000027193.8
Ndufb3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3
chr5_+_147860615 2.37 ENSMUST00000031654.6
Pomp
proteasome maturation protein
chr11_-_20112876 2.20 ENSMUST00000000137.7
Actr2
ARP2 actin-related protein 2
chr15_+_58933774 2.20 ENSMUST00000022980.3
Ndufb9
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9
chr16_+_13903152 2.16 ENSMUST00000128757.1
Mpv17l
Mpv17 transgene, kidney disease mutant-like
chr11_+_120098910 2.09 ENSMUST00000106223.2
1810043H04Rik
RIKEN cDNA 1810043H04 gene
chr3_-_94886945 1.99 ENSMUST00000005923.6
Psmb4
proteasome (prosome, macropain) subunit, beta type 4
chr14_-_101640434 1.98 ENSMUST00000168587.1
Commd6
COMM domain containing 6
chr10_+_77864623 1.96 ENSMUST00000092366.2
Tspear
thrombospondin type laminin G domain and EAR repeats
chr11_-_96916448 1.93 ENSMUST00000103152.4
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr4_+_118409331 1.93 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
Med8
mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)
chr14_-_101640670 1.93 ENSMUST00000100339.2
Commd6
COMM domain containing 6
chr11_-_96916366 1.93 ENSMUST00000144731.1
ENSMUST00000127048.1
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr1_+_167308649 1.85 ENSMUST00000097473.4
Tmco1
transmembrane and coiled-coil domains 1
chr11_+_115163333 1.84 ENSMUST00000021077.3
Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr1_-_179546261 1.80 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr10_-_67285180 1.77 ENSMUST00000159002.1
ENSMUST00000077839.6
Nrbf2
nuclear receptor binding factor 2
chr16_+_64851991 1.76 ENSMUST00000067744.7
Cggbp1
CGG triplet repeat binding protein 1
chr4_-_98383232 1.74 ENSMUST00000143116.1
ENSMUST00000030292.5
ENSMUST00000102793.4
Tm2d1
TM2 domain containing 1
chr19_-_45006385 1.74 ENSMUST00000097715.2
Mrpl43
mitochondrial ribosomal protein L43
chr13_-_4279420 1.74 ENSMUST00000021632.3
Akr1c12
aldo-keto reductase family 1, member C12
chr14_+_51884842 1.73 ENSMUST00000047899.6
ENSMUST00000164902.1
Mettl17
methyltransferase like 17
chr5_-_149636164 1.70 ENSMUST00000076410.4
Hsph1
heat shock 105kDa/110kDa protein 1
chr7_-_126584578 1.70 ENSMUST00000150311.1
Cln3
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr17_+_46711459 1.66 ENSMUST00000002840.8
Pex6
peroxisomal biogenesis factor 6
chr13_+_4191163 1.66 ENSMUST00000021634.2
Akr1c13
aldo-keto reductase family 1, member C13
chr9_+_46273064 1.64 ENSMUST00000156440.1
ENSMUST00000034583.6
ENSMUST00000114552.3
Zfp259
zinc finger protein 259
chr2_-_168230575 1.64 ENSMUST00000109193.1
Dpm1
dolichol-phosphate (beta-D) mannosyltransferase 1
chr11_+_58330744 1.62 ENSMUST00000073128.6
Sh3bp5l
SH3 binding domain protein 5 like
chr6_-_35539765 1.62 ENSMUST00000031866.5
Mtpn
myotrophin
chr17_+_46110982 1.62 ENSMUST00000024763.3
ENSMUST00000123646.1
Mrps18a
mitochondrial ribosomal protein S18A
chr7_-_67645195 1.59 ENSMUST00000032775.5
ENSMUST00000053950.2
Lrrc28
leucine rich repeat containing 28
chr1_+_156035392 1.58 ENSMUST00000111757.3
Tor1aip2
torsin A interacting protein 2
chr11_-_120457936 1.55 ENSMUST00000137632.1
ENSMUST00000044007.2
Oxld1
oxidoreductase like domain containing 1
chr19_-_28963863 1.55 ENSMUST00000161813.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr1_+_4807823 1.55 ENSMUST00000027036.4
ENSMUST00000119612.2
ENSMUST00000137887.1
ENSMUST00000115529.1
ENSMUST00000150971.1
Lypla1
lysophospholipase 1
chr11_-_97150025 1.54 ENSMUST00000118375.1
Tbkbp1
TBK1 binding protein 1
chr11_-_96916407 1.54 ENSMUST00000130774.1
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr2_-_90904827 1.52 ENSMUST00000005647.3
Ndufs3
NADH dehydrogenase (ubiquinone) Fe-S protein 3
chr2_-_168230353 1.50 ENSMUST00000154111.1
Dpm1
dolichol-phosphate (beta-D) mannosyltransferase 1
chr1_-_36244245 1.50 ENSMUST00000046875.7
Uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr12_-_44210061 1.50 ENSMUST00000015049.3
Dnajb9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr3_-_95871367 1.46 ENSMUST00000142437.1
ENSMUST00000067298.4
Mrps21
mitochondrial ribosomal protein S21
chr4_+_48279794 1.45 ENSMUST00000030029.3
Invs
inversin
chr8_-_70139197 1.44 ENSMUST00000075724.7
Rfxank
regulatory factor X-associated ankyrin-containing protein
chr14_+_55591708 1.41 ENSMUST00000019443.8
Rnf31
ring finger protein 31
chr5_-_139826407 1.41 ENSMUST00000182839.1
Gm26938
predicted gene, 26938
chrX_-_169320273 1.40 ENSMUST00000033717.2
ENSMUST00000112115.1
Hccs
holocytochrome c synthetase
chr5_-_149636331 1.40 ENSMUST00000074846.7
ENSMUST00000110498.1
ENSMUST00000127977.1
ENSMUST00000132412.1
Hsph1
heat shock 105kDa/110kDa protein 1
chr8_-_107056650 1.40 ENSMUST00000034391.3
ENSMUST00000095517.5
Cog8
component of oligomeric golgi complex 8
chr7_+_112427706 1.39 ENSMUST00000033030.7
Parva
parvin, alpha
chr14_+_51884982 1.37 ENSMUST00000167984.1
Mettl17
methyltransferase like 17
chr19_-_6084873 1.35 ENSMUST00000160977.1
ENSMUST00000159859.1
Zfpl1
zinc finger like protein 1
chr10_+_128805652 1.35 ENSMUST00000026410.1
Dnajc14
DnaJ (Hsp40) homolog, subfamily C, member 14
chr14_+_47298260 1.35 ENSMUST00000166743.1
Mapk1ip1l
mitogen-activated protein kinase 1 interacting protein 1-like
chr19_+_8871636 1.34 ENSMUST00000096255.5
Ubxn1
UBX domain protein 1
chr10_+_80172934 1.33 ENSMUST00000041882.6
1600002K03Rik
RIKEN cDNA 1600002K03 gene
chr19_+_3282901 1.33 ENSMUST00000025745.3
ENSMUST00000025743.6
Mrpl21
mitochondrial ribosomal protein L21
chr9_+_107563246 1.32 ENSMUST00000010198.3
Tusc2
tumor suppressor candidate 2
chr8_-_124863008 1.32 ENSMUST00000034465.7
2810004N23Rik
RIKEN cDNA 2810004N23 gene
chr19_-_6084679 1.31 ENSMUST00000161548.1
Zfpl1
zinc finger like protein 1
chr2_-_94010807 1.30 ENSMUST00000111240.1
Alkbh3
alkB, alkylation repair homolog 3 (E. coli)
chr10_-_31609184 1.29 ENSMUST00000081989.6
Rnf217
ring finger protein 217
chr3_-_88425094 1.27 ENSMUST00000168755.1
ENSMUST00000057935.6
Slc25a44
solute carrier family 25, member 44
chr7_-_80947499 1.27 ENSMUST00000120285.1
Sec11a
SEC11 homolog A (S. cerevisiae)
chr1_+_74601548 1.27 ENSMUST00000087186.4
Stk36
serine/threonine kinase 36
chr15_-_58933688 1.26 ENSMUST00000110155.1
Tatdn1
TatD DNase domain containing 1
chr7_-_105744312 1.26 ENSMUST00000141116.1
Taf10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr2_-_132815978 1.25 ENSMUST00000039554.6
Trmt6
tRNA methyltransferase 6
chr9_-_79759849 1.24 ENSMUST00000034881.6
Cox7a2
cytochrome c oxidase subunit VIIa 2
chr1_+_4808237 1.23 ENSMUST00000131119.1
Lypla1
lysophospholipase 1
chr2_-_130424673 1.23 ENSMUST00000110277.1
Pced1a
PC-esterase domain containing 1A
chr15_+_76331288 1.22 ENSMUST00000172281.1
Gpaa1
GPI anchor attachment protein 1
chrX_-_168673828 1.21 ENSMUST00000033725.9
ENSMUST00000112137.1
Msl3
male-specific lethal 3 homolog (Drosophila)
chr19_-_6084941 1.20 ENSMUST00000025707.2
ENSMUST00000160712.1
Zfpl1
zinc finger like protein 1
chr19_+_8920358 1.19 ENSMUST00000096243.5
B3gat3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr12_-_81532840 1.18 ENSMUST00000169158.1
ENSMUST00000164431.1
ENSMUST00000163402.1
ENSMUST00000166664.1
ENSMUST00000164386.1
Synj2bp
Gm20498
synaptojanin 2 binding protein
predicted gene 20498
chr7_+_44850393 1.17 ENSMUST00000136232.1
Akt1s1
AKT1 substrate 1 (proline-rich)
chr19_+_8871512 1.17 ENSMUST00000166407.1
Ubxn1
UBX domain protein 1
chr2_+_132686931 1.16 ENSMUST00000061891.4
1110034G24Rik
RIKEN cDNA 1110034G24 gene
chrX_+_7884321 1.16 ENSMUST00000096514.3
ENSMUST00000123277.1
Slc35a2
solute carrier family 35 (UDP-galactose transporter), member A2
chr5_-_115348953 1.13 ENSMUST00000040154.8
Cox6a1
cytochrome c oxidase subunit VIa polypeptide 1
chr16_+_3872368 1.10 ENSMUST00000151988.1
Naa60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr19_+_28963892 1.10 ENSMUST00000045674.2
Ppapdc2
phosphatidic acid phosphatase type 2 domain containing 2
chr2_-_10080322 1.10 ENSMUST00000145530.1
ENSMUST00000026887.7
ENSMUST00000114896.1
ENSMUST00000114897.2
Atp5c1
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
chr5_-_139826837 1.10 ENSMUST00000182602.1
ENSMUST00000031531.7
Psmg3
proteasome (prosome, macropain) assembly chaperone 3
chr2_+_39008076 1.09 ENSMUST00000112862.1
ENSMUST00000090993.5
Arpc5l
actin related protein 2/3 complex, subunit 5-like
chr4_+_107178399 1.09 ENSMUST00000030361.4
ENSMUST00000128123.1
ENSMUST00000106753.1
Tmem59
transmembrane protein 59
chr19_-_45660312 1.08 ENSMUST00000046869.4
Fbxw4
F-box and WD-40 domain protein 4
chrX_-_141725181 1.07 ENSMUST00000067841.7
Irs4
insulin receptor substrate 4
chr7_-_46919915 1.06 ENSMUST00000143413.1
ENSMUST00000014546.8
Tsg101
tumor susceptibility gene 101
chrX_+_7884022 1.03 ENSMUST00000115660.4
Slc35a2
solute carrier family 35 (UDP-galactose transporter), member A2
chr17_+_35121455 1.03 ENSMUST00000173380.1
ENSMUST00000173043.3
ENSMUST00000165306.2
Gpank1
G patch domain and ankyrin repeats 1
chr15_-_99474696 1.01 ENSMUST00000040313.4
Bcdin3d
BCDIN3 domain containing
chr15_-_57892358 1.01 ENSMUST00000022993.5
Derl1
Der1-like domain family, member 1
chr11_-_120624973 1.00 ENSMUST00000106183.2
ENSMUST00000080202.5
Sirt7
sirtuin 7
chr2_-_127208274 0.99 ENSMUST00000056146.1
1810024B03Rik
RIKEN cDNA 1810024B03 gene
chr15_+_9140527 0.99 ENSMUST00000090380.4
Lmbrd2
LMBR1 domain containing 2
chr7_+_127233044 0.97 ENSMUST00000106312.3
Zfp553
zinc finger protein 553
chr16_-_87432597 0.96 ENSMUST00000039449.7
Ltn1
listerin E3 ubiquitin protein ligase 1
chr6_-_113377866 0.96 ENSMUST00000032410.7
Tada3
transcriptional adaptor 3
chr18_+_53862087 0.96 ENSMUST00000069597.6
Csnk1g3
casein kinase 1, gamma 3
chr11_+_106256140 0.95 ENSMUST00000021049.2
Psmc5
protease (prosome, macropain) 26S subunit, ATPase 5
chr4_-_40948196 0.94 ENSMUST00000030125.4
ENSMUST00000108089.1
Bag1
BCL2-associated athanogene 1
chr13_+_46669517 0.94 ENSMUST00000099547.3
C78339
expressed sequence C78339
chr19_+_6996114 0.94 ENSMUST00000088223.5
Trpt1
tRNA phosphotransferase 1
chr7_-_80947765 0.93 ENSMUST00000026818.5
ENSMUST00000117383.1
ENSMUST00000119980.1
Sec11a
SEC11 homolog A (S. cerevisiae)
chr4_-_48279544 0.93 ENSMUST00000030028.4
Erp44
endoplasmic reticulum protein 44
chr11_-_79962374 0.92 ENSMUST00000108241.1
ENSMUST00000043152.5
Utp6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr7_-_13034722 0.92 ENSMUST00000005711.4
Chmp2a
charged multivesicular body protein 2A
chr4_-_116017854 0.91 ENSMUST00000049095.5
Faah
fatty acid amide hydrolase
chr6_-_124965403 0.89 ENSMUST00000129446.1
ENSMUST00000032220.8
Cops7a
COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)
chr4_+_31964081 0.89 ENSMUST00000037607.4
ENSMUST00000080933.6
ENSMUST00000108183.1
ENSMUST00000108184.2
Map3k7
mitogen-activated protein kinase kinase kinase 7
chr14_-_18331855 0.88 ENSMUST00000022296.6
Ube2e1
ubiquitin-conjugating enzyme E2E 1
chr10_+_79669410 0.88 ENSMUST00000020552.5
Tpgs1
tubulin polyglutamylase complex subunit 1
chr7_+_80261202 0.88 ENSMUST00000117989.1
Ngrn
neugrin, neurite outgrowth associated
chrX_+_7884244 0.88 ENSMUST00000115663.3
Slc35a2
solute carrier family 35 (UDP-galactose transporter), member A2
chr11_-_120467414 0.87 ENSMUST00000076921.6
Arl16
ADP-ribosylation factor-like 16
chr11_+_61653259 0.87 ENSMUST00000004959.2
Grap
GRB2-related adaptor protein
chr2_-_84715160 0.86 ENSMUST00000035840.5
Zdhhc5
zinc finger, DHHC domain containing 5
chr11_-_77078404 0.86 ENSMUST00000102494.1
Ccdc55
coiled-coil domain containing 55
chr3_+_90052814 0.86 ENSMUST00000160640.1
ENSMUST00000029552.6
ENSMUST00000162114.1
ENSMUST00000068798.6
4933434E20Rik
RIKEN cDNA 4933434E20 gene
chr9_-_57645561 0.86 ENSMUST00000034863.6
Csk
c-src tyrosine kinase
chr11_-_120098673 0.85 ENSMUST00000093901.5
ENSMUST00000026442.4
ENSMUST00000106225.3
Enthd2
ENTH domain containing 2
chr4_-_124851152 0.85 ENSMUST00000185036.1
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chr17_-_15498263 0.85 ENSMUST00000014913.9
Psmb1
proteasome (prosome, macropain) subunit, beta type 1
chr7_+_81762925 0.85 ENSMUST00000042166.4
Fam103a1
family with sequence similarity 103, member A1
chr11_+_88204396 0.84 ENSMUST00000118784.1
ENSMUST00000139170.1
ENSMUST00000107915.3
ENSMUST00000144070.1
Mrps23
mitochondrial ribosomal protein S23
chr2_-_94010729 0.84 ENSMUST00000040005.6
ENSMUST00000126378.1
Alkbh3
alkB, alkylation repair homolog 3 (E. coli)
chr4_-_119173849 0.84 ENSMUST00000052715.4
ENSMUST00000179290.1
ENSMUST00000154226.1
Zfp691
zinc finger protein 691
chr5_-_145140238 0.84 ENSMUST00000031627.8
Pdap1
PDGFA associated protein 1
chr6_+_125009665 0.84 ENSMUST00000046064.10
ENSMUST00000152752.1
ENSMUST00000088308.3
ENSMUST00000112425.1
ENSMUST00000084275.5
Zfp384
zinc finger protein 384
chr17_-_35121173 0.83 ENSMUST00000174024.1
Csnk2b
casein kinase 2, beta polypeptide
chr4_+_124802543 0.82 ENSMUST00000138807.1
ENSMUST00000030723.2
ENSMUST00000175875.1
Mtf1
metal response element binding transcription factor 1
chr5_+_145140362 0.82 ENSMUST00000162594.1
ENSMUST00000162308.1
ENSMUST00000159018.1
ENSMUST00000160075.1
Bud31
BUD31 homolog (yeast)
chr6_-_88518760 0.82 ENSMUST00000032168.5
Sec61a1
Sec61 alpha 1 subunit (S. cerevisiae)
chr11_+_58330712 0.82 ENSMUST00000116376.2
Sh3bp5l
SH3 binding domain protein 5 like
chr7_+_127233227 0.81 ENSMUST00000056232.6
Zfp553
zinc finger protein 553
chr9_+_20644792 0.81 ENSMUST00000162303.1
ENSMUST00000161486.1
Ubl5
ubiquitin-like 5
chr17_-_35121213 0.81 ENSMUST00000025246.6
Csnk2b
casein kinase 2, beta polypeptide
chr11_+_118428493 0.80 ENSMUST00000017590.2
C1qtnf1
C1q and tumor necrosis factor related protein 1
chr11_-_50210765 0.80 ENSMUST00000143379.1
ENSMUST00000015981.5
ENSMUST00000102774.4
Sqstm1
sequestosome 1
chrX_+_144317799 0.80 ENSMUST00000070801.4
Alg13
asparagine-linked glycosylation 13
chr11_+_94653767 0.79 ENSMUST00000025278.7
Mrpl27
mitochondrial ribosomal protein L27
chr15_+_76331231 0.79 ENSMUST00000023221.6
Gpaa1
GPI anchor attachment protein 1
chr7_+_5080214 0.79 ENSMUST00000098845.3
ENSMUST00000146317.1
ENSMUST00000153169.1
ENSMUST00000045277.6
Epn1
epsin 1
chr5_-_31220491 0.79 ENSMUST00000031032.7
Ppm1g
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
chr15_+_5185700 0.78 ENSMUST00000081640.5
Ttc33
tetratricopeptide repeat domain 33
chr19_+_45006475 0.78 ENSMUST00000026227.2
Peo1
progressive external ophthalmoplegia 1 (human)
chr17_-_35121030 0.78 ENSMUST00000174306.1
Csnk2b
casein kinase 2, beta polypeptide
chr11_+_5955693 0.77 ENSMUST00000002818.8
Ykt6
YKT6 homolog (S. Cerevisiae)
chr15_+_5185519 0.77 ENSMUST00000118193.1
ENSMUST00000022751.8
Ttc33
tetratricopeptide repeat domain 33
chr1_+_74601441 0.76 ENSMUST00000087183.4
ENSMUST00000148456.1
ENSMUST00000113694.1
Stk36
serine/threonine kinase 36
chr6_-_113377712 0.75 ENSMUST00000113107.1
ENSMUST00000113106.1
Tada3
transcriptional adaptor 3
chr1_-_58586191 0.75 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
Fam126b
family with sequence similarity 126, member B
chr2_+_152226839 0.75 ENSMUST00000099224.3
ENSMUST00000124791.1
ENSMUST00000133119.1
Csnk2a1
casein kinase 2, alpha 1 polypeptide
chr2_+_160888101 0.74 ENSMUST00000109455.2
ENSMUST00000040872.6
Lpin3
lipin 3
chr8_-_84147858 0.74 ENSMUST00000117424.2
ENSMUST00000040383.8
Cc2d1a
coiled-coil and C2 domain containing 1A
chr9_+_20581296 0.74 ENSMUST00000115557.2
Zfp846
zinc finger protein 846
chr9_+_20644851 0.74 ENSMUST00000161882.1
Ubl5
ubiquitin-like 5
chr17_-_35121423 0.74 ENSMUST00000173114.1
Csnk2b
casein kinase 2, beta polypeptide
chr2_+_160888156 0.74 ENSMUST00000109457.2
Lpin3
lipin 3
chrX_-_94212685 0.73 ENSMUST00000050328.8
Eif2s3x
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked
chr14_-_70520254 0.73 ENSMUST00000022693.7
Bmp1
bone morphogenetic protein 1
chr19_+_5366764 0.73 ENSMUST00000025759.7
Eif1ad
eukaryotic translation initiation factor 1A domain containing
chr5_-_135744206 0.71 ENSMUST00000153399.1
ENSMUST00000043378.2
Tmem120a
transmembrane protein 120A
chr4_-_118409219 0.71 ENSMUST00000075406.5
Szt2
seizure threshold 2
chr19_+_46599081 0.71 ENSMUST00000138302.2
ENSMUST00000099376.4
Wbp1l
WW domain binding protein 1 like
chr4_-_155086271 0.71 ENSMUST00000030914.3
Rer1
RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)
chr11_-_16508069 0.70 ENSMUST00000109641.1
Sec61g
SEC61, gamma subunit
chr2_+_130424321 0.70 ENSMUST00000128994.1
ENSMUST00000028900.9
Vps16
vacuolar protein sorting 16 (yeast)
chrX_+_42068398 0.70 ENSMUST00000115095.2
Xiap
X-linked inhibitor of apoptosis
chr12_-_78861636 0.69 ENSMUST00000021536.7
Atp6v1d
ATPase, H+ transporting, lysosomal V1 subunit D
chr4_+_40948401 0.69 ENSMUST00000030128.5
Chmp5
charged multivesicular body protein 5
chr4_-_119174178 0.68 ENSMUST00000106355.3
Zfp691
zinc finger protein 691
chr1_+_91250482 0.68 ENSMUST00000171112.1
Ube2f
ubiquitin-conjugating enzyme E2F (putative)
chr12_+_85110833 0.68 ENSMUST00000053811.8
Dlst
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr11_+_88204380 0.68 ENSMUST00000024486.7
Mrps23
mitochondrial ribosomal protein S23
chr11_+_87592145 0.68 ENSMUST00000103179.3
ENSMUST00000092802.5
ENSMUST00000146871.1
Mtmr4
myotubularin related protein 4
chr11_+_62458414 0.67 ENSMUST00000014389.5
Pigl
phosphatidylinositol glycan anchor biosynthesis, class L
chr14_-_31001311 0.67 ENSMUST00000161219.1
ENSMUST00000182501.1
Spcs1
signal peptidase complex subunit 1 homolog (S. cerevisiae)
chr11_-_16508149 0.67 ENSMUST00000109642.1
Sec61g
SEC61, gamma subunit
chr8_+_110847015 0.66 ENSMUST00000172668.1
ENSMUST00000034203.10
ENSMUST00000174398.1
Cog4
component of oligomeric golgi complex 4
chrX_-_100625901 0.66 ENSMUST00000059099.6
Pdzd11
PDZ domain containing 11
chr1_+_33669816 0.66 ENSMUST00000051203.5
1700001G17Rik
RIKEN cDNA 1700001G17 gene
chr13_-_74208661 0.66 ENSMUST00000035934.5
Exoc3
exocyst complex component 3
chr4_+_118620799 0.65 ENSMUST00000030501.8
Ebna1bp2
EBNA1 binding protein 2
chr6_-_124965207 0.65 ENSMUST00000148485.1
Cops7a
COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)
chr5_-_36830647 0.64 ENSMUST00000031002.3
Man2b2
mannosidase 2, alpha B2
chr3_-_65392579 0.63 ENSMUST00000029414.5
Ssr3
signal sequence receptor, gamma
chr15_-_85811644 0.63 ENSMUST00000144067.1
ENSMUST00000134631.1
ENSMUST00000154814.1
ENSMUST00000071876.6
ENSMUST00000150995.1
Cdpf1
cysteine rich, DPF motif domain containing 1
chr2_-_10080055 0.62 ENSMUST00000130067.1
ENSMUST00000139810.1
Atp5c1
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
chr11_+_97041554 0.62 ENSMUST00000001485.3
Mrpl10
mitochondrial ribosomal protein L10
chrX_+_107816477 0.61 ENSMUST00000143975.1
ENSMUST00000144695.1
ENSMUST00000167154.1
Fam46d
family with sequence similarity 46, member D
chr7_+_39449479 0.60 ENSMUST00000061201.8
Zfp939
zinc finger protein 939
chr2_+_37443273 0.60 ENSMUST00000133434.1
ENSMUST00000061179.5
Rabgap1
RAB GTPase activating protein 1
chr1_+_91250311 0.58 ENSMUST00000059743.5
ENSMUST00000178627.1
ENSMUST00000171165.1
Ube2f
ubiquitin-conjugating enzyme E2F (putative)

Network of associatons between targets according to the STRING database.

First level regulatory network of Etv6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.8 3.1 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.6 1.8 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.6 3.6 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.6 5.4 GO:0071569 protein ufmylation(GO:0071569)
0.6 3.4 GO:0051790 acetate metabolic process(GO:0006083) short-chain fatty acid biosynthetic process(GO:0051790)
0.6 1.7 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.5 1.6 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.5 2.1 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552) oxidative single-stranded RNA demethylation(GO:0035553)
0.5 2.0 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.5 2.5 GO:1903093 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.4 3.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.4 1.3 GO:0052564 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.4 2.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.4 1.2 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.4 1.1 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.4 2.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.4 1.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.3 2.0 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.3 0.3 GO:0018307 enzyme active site formation(GO:0018307)
0.3 0.9 GO:1903722 regulation of centriole elongation(GO:1903722)
0.3 2.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.3 1.5 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.3 1.0 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.2 1.2 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.2 0.7 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.2 0.7 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.2 3.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 3.4 GO:0006465 signal peptide processing(GO:0006465)
0.2 1.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 1.7 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.2 0.9 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.2 3.0 GO:0000338 protein deneddylation(GO:0000338)
0.2 0.5 GO:0019085 early viral transcription(GO:0019085)
0.2 1.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 2.4 GO:0043248 proteasome assembly(GO:0043248)
0.1 2.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 2.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.8 GO:0039019 pronephric nephron development(GO:0039019)
0.1 1.0 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 0.9 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.7 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 1.6 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 1.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.3 GO:0006983 ER overload response(GO:0006983)
0.1 0.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 1.4 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.1 1.3 GO:0070365 hepatocyte differentiation(GO:0070365)
0.1 1.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.9 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.8 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.2 GO:0000239 pachytene(GO:0000239)
0.1 0.7 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.6 GO:0006013 mannose metabolic process(GO:0006013)
0.1 2.6 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.4 GO:0071502 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) negative regulation of serotonin secretion(GO:0014063) cellular response to temperature stimulus(GO:0071502)
0.1 0.9 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 4.2 GO:0032543 mitochondrial translation(GO:0032543)
0.1 0.4 GO:0030913 paranodal junction assembly(GO:0030913)
0.1 1.5 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.1 1.4 GO:0017004 cytochrome complex assembly(GO:0017004)
0.1 1.7 GO:0045116 protein neddylation(GO:0045116)
0.1 1.0 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.1 0.2 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.3 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 2.4 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 1.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 1.0 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 0.1 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.1 1.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.8 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 3.4 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.1 0.5 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.7 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.7 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.5 GO:2000303 regulation of ceramide biosynthetic process(GO:2000303)
0.0 1.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 1.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.7 GO:0051601 exocyst localization(GO:0051601)
0.0 0.7 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0 3.9 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.4 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.8 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 1.3 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 1.8 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 1.0 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 1.0 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 1.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 1.5 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.8 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.7 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 0.6 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.4 GO:1903543 regulation of exosomal secretion(GO:1903541) positive regulation of exosomal secretion(GO:1903543)
0.0 0.8 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.3 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:1903538 meiotic sister chromatid cohesion, centromeric(GO:0051754) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0 0.7 GO:0071174 mitotic spindle checkpoint(GO:0071174)
0.0 0.7 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.6 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.4 GO:0006986 response to unfolded protein(GO:0006986)
0.0 1.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 1.0 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.3 GO:0035357 peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.0 1.5 GO:0045333 cellular respiration(GO:0045333)
0.0 3.1 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.8 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.7 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.3 GO:0070266 necroptotic process(GO:0070266)
0.0 0.9 GO:0009062 fatty acid catabolic process(GO:0009062)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.6 3.9 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.5 1.5 GO:0097543 ciliary inversin compartment(GO:0097543)
0.4 3.4 GO:0005787 signal peptidase complex(GO:0005787)
0.4 2.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.3 2.0 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.3 0.9 GO:0031533 mRNA cap methyltransferase complex(GO:0031533)
0.3 1.4 GO:0071797 LUBAC complex(GO:0071797)
0.3 0.8 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.3 0.8 GO:0044753 amphisome(GO:0044753)
0.2 1.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.2 2.2 GO:0030478 actin cap(GO:0030478)
0.2 1.2 GO:0072487 MSL complex(GO:0072487)
0.2 1.7 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 1.3 GO:0000125 PCAF complex(GO:0000125)
0.2 0.8 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.2 0.8 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.2 0.8 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888)
0.2 2.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 1.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.2 3.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 0.9 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.7 GO:1990130 Iml1 complex(GO:1990130)
0.1 2.1 GO:0017119 Golgi transport complex(GO:0017119)
0.1 4.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 6.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.7 GO:0000124 SAGA complex(GO:0000124)
0.1 1.0 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 2.8 GO:0005839 proteasome core complex(GO:0005839)
0.1 1.1 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.8 GO:0097441 basilar dendrite(GO:0097441)
0.1 1.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.2 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.7 GO:0033263 CORVET complex(GO:0033263)
0.1 1.0 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 5.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.9 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.8 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 2.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.2 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 0.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 2.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 1.8 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 2.0 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 4.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 2.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.2 GO:0016592 mediator complex(GO:0016592)
0.0 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.6 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 4.2 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 2.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.0 GO:0034657 GID complex(GO:0034657)
0.0 0.0 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.8 3.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.8 3.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.7 2.1 GO:0051747 cytosine C-5 DNA demethylase activity(GO:0051747)
0.6 1.8 GO:0045159 myosin II binding(GO:0045159)
0.5 1.8 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.4 4.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.4 2.5 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.4 2.0 GO:0034235 GPI anchor binding(GO:0034235)
0.3 1.0 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.3 0.9 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity(GO:0004482)
0.3 2.8 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3 1.0 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.2 1.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 1.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.2 0.7 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 5.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 0.9 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 3.1 GO:0042166 acetylcholine binding(GO:0042166)
0.2 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 1.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.9 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 3.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 1.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 2.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.1 GO:0046790 virion binding(GO:0046790)
0.1 0.3 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.1 1.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 1.5 GO:0031386 protein tag(GO:0031386)
0.1 2.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.5 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 3.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.8 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 3.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.8 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.3 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.9 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 1.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.6 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.9 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.9 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 1.3 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 6.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 1.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.6 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 6.1 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 0.4 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 1.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 2.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.3 GO:0005518 collagen binding(GO:0005518)
0.0 1.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0030515 snoRNA binding(GO:0030515)
0.0 1.9 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.8 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 1.2 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 3.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 3.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 3.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.8 PID ARF 3PATHWAY Arf1 pathway
0.0 1.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 4.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.7 PID INSULIN PATHWAY Insulin Pathway
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 3.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 3.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 3.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.9 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 8.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 6.4 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.1 1.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 2.9 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 1.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.8 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 2.7 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 4.7 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 1.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 3.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 0.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 0.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.9 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.1 1.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.9 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse