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GSE58827: Dynamics of the Mouse Liver

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Results for Foxa2_Foxa1

Z-value: 2.03

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Transcription factors associated with Foxa2_Foxa1

Gene Symbol Gene ID Gene Info
Foxa2
ENSMUSG00000037025.5 forkhead box A2
Foxa1
ENSMUSG00000035451.6 forkhead box A1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxa2mm10_v2_chr2_-_148046896_1480469910.684.1e-06Click!
Foxa1mm10_v2_chr12_-_57546121_575461410.335.2e-02Click!

Activity profile of Foxa2_Foxa1 motif

Sorted Z-values of Foxa2_Foxa1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_113258837 55.12 ENSMUST00000098673.3
Amy2a5
amylase 2a5
chr3_-_113532288 39.00 ENSMUST00000132353.1
Amy2a1
amylase 2a1
chr6_+_30541582 28.17 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr3_-_20275659 27.11 ENSMUST00000011607.5
Cpb1
carboxypeptidase B1 (tissue)
chr17_-_31144271 25.50 ENSMUST00000024826.7
Tff2
trefoil factor 2 (spasmolytic protein 1)
chr2_-_62483637 20.03 ENSMUST00000136686.1
ENSMUST00000102733.3
Gcg
glucagon
chr7_+_131032061 17.42 ENSMUST00000084509.3
Dmbt1
deleted in malignant brain tumors 1
chr6_+_142298419 16.69 ENSMUST00000041993.2
Iapp
islet amyloid polypeptide
chr3_+_107230608 13.08 ENSMUST00000179399.1
A630076J17Rik
RIKEN cDNA A630076J17 gene
chr9_+_46268601 12.35 ENSMUST00000121598.1
Apoa5
apolipoprotein A-V
chr6_-_136922169 11.19 ENSMUST00000032343.6
Erp27
endoplasmic reticulum protein 27
chr5_-_108795352 8.90 ENSMUST00000004943.1
Tmed11
transmembrane emp24 protein transport domain containing
chr6_-_41446062 8.88 ENSMUST00000095999.5
Gm10334
predicted gene 10334
chr3_-_113324052 8.36 ENSMUST00000179314.1
Amy2a3
amylase 2a3
chr3_-_113291449 8.28 ENSMUST00000179568.1
Amy2a4
amylase 2a4
chr4_-_57916283 8.18 ENSMUST00000063816.5
D630039A03Rik
RIKEN cDNA D630039A03 gene
chr7_+_140763739 7.70 ENSMUST00000026552.7
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
chr15_+_10223974 7.11 ENSMUST00000128450.1
ENSMUST00000148257.1
ENSMUST00000128921.1
Prlr
prolactin receptor
chr1_+_130865669 6.82 ENSMUST00000038829.5
Faim3
Fas apoptotic inhibitory molecule 3
chr3_-_145032765 6.28 ENSMUST00000029919.5
Clca3
chloride channel calcium activated 3
chr2_+_164403194 6.18 ENSMUST00000017151.1
Rbpjl
recombination signal binding protein for immunoglobulin kappa J region-like
chr4_-_6275629 6.16 ENSMUST00000029905.1
Cyp7a1
cytochrome P450, family 7, subfamily a, polypeptide 1
chr19_+_23141183 4.80 ENSMUST00000036884.1
Klf9
Kruppel-like factor 9
chr6_-_87388878 4.75 ENSMUST00000032127.4
Gkn3
gastrokine 3
chr2_+_58755177 4.73 ENSMUST00000102755.3
Upp2
uridine phosphorylase 2
chr4_+_34893772 4.64 ENSMUST00000029975.3
ENSMUST00000135871.1
ENSMUST00000108130.1
Cga
glycoprotein hormones, alpha subunit
chr17_-_12675833 4.64 ENSMUST00000024596.8
Slc22a1
solute carrier family 22 (organic cation transporter), member 1
chr2_-_134554348 4.38 ENSMUST00000028704.2
Hao1
hydroxyacid oxidase 1, liver
chr2_+_58754910 4.13 ENSMUST00000059102.6
Upp2
uridine phosphorylase 2
chr16_+_22892035 4.01 ENSMUST00000023583.5
Ahsg
alpha-2-HS-glycoprotein
chr12_-_80968075 3.99 ENSMUST00000095572.4
Slc10a1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr1_-_130661584 3.94 ENSMUST00000137276.2
C4bp
complement component 4 binding protein
chr9_+_37539255 3.72 ENSMUST00000002008.5
Vsig2
V-set and immunoglobulin domain containing 2
chr10_-_41611319 3.67 ENSMUST00000179614.1
Ccdc162
coiled-coil domain containing 162
chr17_+_47726834 3.53 ENSMUST00000024782.5
ENSMUST00000144955.1
Pgc
progastricsin (pepsinogen C)
chr5_-_89457763 3.49 ENSMUST00000049209.8
Gc
group specific component
chr17_-_31165045 3.46 ENSMUST00000024831.6
Tff1
trefoil factor 1
chr4_+_150853919 3.44 ENSMUST00000073600.2
Errfi1
ERBB receptor feedback inhibitor 1
chr3_+_19957240 3.35 ENSMUST00000108325.2
Cp
ceruloplasmin
chr16_-_29378667 3.26 ENSMUST00000143373.1
ENSMUST00000075806.4
Atp13a5
ATPase type 13A5
chr2_-_148040196 3.25 ENSMUST00000136555.1
9030622O22Rik
RIKEN cDNA 9030622O22 gene
chr2_+_69219971 3.24 ENSMUST00000005364.5
ENSMUST00000112317.2
G6pc2
glucose-6-phosphatase, catalytic, 2
chr4_-_127354074 3.21 ENSMUST00000106090.1
ENSMUST00000060419.1
Gjb4
gap junction protein, beta 4
chr1_-_130661613 3.18 ENSMUST00000027657.7
C4bp
complement component 4 binding protein
chr17_+_12378603 3.05 ENSMUST00000014578.5
Plg
plasminogen
chr12_-_103773592 3.02 ENSMUST00000078869.5
Serpina1d
serine (or cysteine) peptidase inhibitor, clade A, member 1D
chr13_+_112467504 3.01 ENSMUST00000183868.1
Il6st
interleukin 6 signal transducer
chr10_+_111506286 2.98 ENSMUST00000164773.1
Phlda1
pleckstrin homology-like domain, family A, member 1
chr1_-_157256682 2.92 ENSMUST00000134543.1
Rasal2
RAS protein activator like 2
chr4_+_102570065 2.91 ENSMUST00000097950.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr17_+_12584183 2.85 ENSMUST00000046959.7
Slc22a2
solute carrier family 22 (organic cation transporter), member 2
chr14_+_41131777 2.85 ENSMUST00000022314.3
ENSMUST00000170719.1
Sftpa1
surfactant associated protein A1
chr13_+_4049001 2.66 ENSMUST00000118717.2
Akr1c14
aldo-keto reductase family 1, member C14
chr15_-_3303521 2.66 ENSMUST00000165386.1
Ccdc152
coiled-coil domain containing 152
chr2_-_160859601 2.63 ENSMUST00000103112.1
Zhx3
zinc fingers and homeoboxes 3
chr7_-_142661858 2.54 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr10_+_60106452 2.46 ENSMUST00000165024.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr15_-_97020322 2.44 ENSMUST00000166223.1
Slc38a4
solute carrier family 38, member 4
chr13_+_23807027 2.44 ENSMUST00000006786.4
ENSMUST00000099697.2
Slc17a2
solute carrier family 17 (sodium phosphate), member 2
chr11_+_94565039 2.43 ENSMUST00000040418.8
Chad
chondroadherin
chr12_-_103738158 2.43 ENSMUST00000095450.4
Serpina1b
serine (or cysteine) preptidase inhibitor, clade A, member 1B
chr12_-_103904887 2.36 ENSMUST00000074051.5
Serpina1c
serine (or cysteine) peptidase inhibitor, clade A, member 1C
chr2_-_102400863 2.35 ENSMUST00000102573.1
Trim44
tripartite motif-containing 44
chr16_+_33518528 2.31 ENSMUST00000119173.1
Slc12a8
solute carrier family 12 (potassium/chloride transporters), member 8
chr11_-_68386821 2.31 ENSMUST00000021284.3
Ntn1
netrin 1
chr7_-_105600103 2.31 ENSMUST00000033185.8
Hpx
hemopexin
chr1_-_97977233 2.30 ENSMUST00000161567.1
Pam
peptidylglycine alpha-amidating monooxygenase
chr9_-_71163224 2.26 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr16_+_91269759 2.23 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr8_-_65129317 2.23 ENSMUST00000098713.3
BC030870
cDNA sequence BC030870
chr3_+_98222148 2.22 ENSMUST00000029469.4
Reg4
regenerating islet-derived family, member 4
chr11_-_60036917 2.21 ENSMUST00000102692.3
Pemt
phosphatidylethanolamine N-methyltransferase
chr3_+_19957088 2.19 ENSMUST00000108328.1
Cp
ceruloplasmin
chr18_-_38918642 2.18 ENSMUST00000040647.4
Fgf1
fibroblast growth factor 1
chr5_+_90561102 2.05 ENSMUST00000094615.4
5830473C10Rik
RIKEN cDNA 5830473C10 gene
chr8_+_45628176 2.04 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr13_+_40859768 2.02 ENSMUST00000110191.2
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr15_-_5108469 1.95 ENSMUST00000141020.1
Card6
caspase recruitment domain family, member 6
chr11_+_78499087 1.90 ENSMUST00000017488.4
Vtn
vitronectin
chr11_-_68386974 1.88 ENSMUST00000135141.1
Ntn1
netrin 1
chr3_+_19957037 1.82 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp
ceruloplasmin
chr1_-_139858684 1.82 ENSMUST00000094489.3
Cfhr2
complement factor H-related 2
chr10_-_61979073 1.79 ENSMUST00000105453.1
ENSMUST00000105452.2
ENSMUST00000105454.2
Col13a1
collagen, type XIII, alpha 1
chr19_-_58455903 1.79 ENSMUST00000131877.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr1_+_67123015 1.78 ENSMUST00000027144.7
Cps1
carbamoyl-phosphate synthetase 1
chr2_-_147186389 1.73 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2
NK2 homeobox 2
chr14_-_41185188 1.72 ENSMUST00000077136.3
Sftpd
surfactant associated protein D
chr1_+_34121250 1.71 ENSMUST00000183006.1
Dst
dystonin
chr6_-_3494587 1.71 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr8_-_45294854 1.71 ENSMUST00000116473.2
Klkb1
kallikrein B, plasma 1
chr9_-_107668967 1.70 ENSMUST00000177567.1
Slc38a3
solute carrier family 38, member 3
chr19_-_58455161 1.63 ENSMUST00000135730.1
ENSMUST00000152507.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr17_-_56121946 1.62 ENSMUST00000041357.7
Lrg1
leucine-rich alpha-2-glycoprotein 1
chr16_-_38294774 1.61 ENSMUST00000023504.4
Nr1i2
nuclear receptor subfamily 1, group I, member 2
chrX_+_57212110 1.60 ENSMUST00000033466.1
Cd40lg
CD40 ligand
chr16_+_33518278 1.59 ENSMUST00000122427.1
ENSMUST00000059056.8
Slc12a8
solute carrier family 12 (potassium/chloride transporters), member 8
chr6_-_83656082 1.58 ENSMUST00000014686.2
Clec4f
C-type lectin domain family 4, member f
chr9_+_74848437 1.56 ENSMUST00000161862.1
ENSMUST00000162089.1
ENSMUST00000160017.1
ENSMUST00000160950.1
Gm16551
Gm20649
predicted gene 16551
predicted gene 20649
chr7_+_113765998 1.55 ENSMUST00000046687.9
Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr14_-_30943275 1.55 ENSMUST00000006704.8
ENSMUST00000163118.1
Itih1
inter-alpha trypsin inhibitor, heavy chain 1
chr2_+_176236860 1.53 ENSMUST00000166464.1
2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr6_+_129533183 1.49 ENSMUST00000032264.6
Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr17_+_28858411 1.48 ENSMUST00000114737.1
ENSMUST00000056866.5
Pnpla1
patatin-like phospholipase domain containing 1
chrX_-_108664891 1.47 ENSMUST00000178160.1
Gm379
predicted gene 379
chr1_-_179546261 1.45 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr11_+_32000452 1.42 ENSMUST00000020537.2
ENSMUST00000109409.1
Nsg2
neuron specific gene family member 2
chr14_+_73237891 1.42 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr1_+_87574016 1.42 ENSMUST00000166259.1
ENSMUST00000172222.1
ENSMUST00000163606.1
Neu2
neuraminidase 2
chr5_-_51567717 1.42 ENSMUST00000127135.1
ENSMUST00000151104.1
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr4_-_63154130 1.38 ENSMUST00000030041.4
Ambp
alpha 1 microglobulin/bikunin
chr6_+_34709610 1.37 ENSMUST00000031775.6
Cald1
caldesmon 1
chr2_+_158306493 1.36 ENSMUST00000016168.2
ENSMUST00000109491.1
Lbp
lipopolysaccharide binding protein
chr6_+_83743010 1.34 ENSMUST00000006431.6
Atp6v1b1
ATPase, H+ transporting, lysosomal V1 subunit B1
chr5_+_43515513 1.32 ENSMUST00000167522.1
ENSMUST00000144558.1
ENSMUST00000076939.6
C1qtnf7
C1q and tumor necrosis factor related protein 7
chrX_+_101376359 1.31 ENSMUST00000119080.1
Gjb1
gap junction protein, beta 1
chr10_+_128909866 1.26 ENSMUST00000026407.7
Cd63
CD63 antigen
chr8_-_84773381 1.25 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr9_+_55326913 1.25 ENSMUST00000085754.3
ENSMUST00000034862.4
AI118078
expressed sequence AI118078
chr19_+_26623419 1.25 ENSMUST00000176584.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr12_-_56613270 1.24 ENSMUST00000072631.5
Nkx2-9
NK2 homeobox 9
chr15_+_25940846 1.20 ENSMUST00000110438.1
Fam134b
family with sequence similarity 134, member B
chr2_+_27676440 1.18 ENSMUST00000129514.1
Rxra
retinoid X receptor alpha
chr10_+_87861309 1.18 ENSMUST00000122100.1
Igf1
insulin-like growth factor 1
chr16_-_63864114 1.18 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr3_+_5218516 1.18 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr19_-_58455398 1.18 ENSMUST00000026076.7
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr2_+_50066429 1.17 ENSMUST00000112712.3
ENSMUST00000128451.1
ENSMUST00000053208.7
Lypd6
LY6/PLAUR domain containing 6
chrX_+_150594420 1.16 ENSMUST00000112713.2
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr18_-_62756275 1.15 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik
RIKEN cDNA 2700046A07 gene
chr6_+_134830216 1.12 ENSMUST00000111937.1
Crebl2
cAMP responsive element binding protein-like 2
chrX_-_94123087 1.11 ENSMUST00000113925.1
Zfx
zinc finger protein X-linked
chrX_-_139782353 1.10 ENSMUST00000101217.3
Ripply1
ripply1 homolog (zebrafish)
chr12_-_103863551 1.07 ENSMUST00000085056.6
ENSMUST00000072876.5
ENSMUST00000124717.1
Serpina1a
serine (or cysteine) peptidase inhibitor, clade A, member 1A
chr4_+_43669610 1.07 ENSMUST00000107866.1
Tmem8b
transmembrane protein 8B
chr1_+_132298606 1.05 ENSMUST00000046071.4
Klhdc8a
kelch domain containing 8A
chr2_+_4718145 1.05 ENSMUST00000056914.6
Bend7
BEN domain containing 7
chr15_-_5108492 1.04 ENSMUST00000118365.2
Card6
caspase recruitment domain family, member 6
chr16_-_95586585 1.04 ENSMUST00000077773.6
Erg
avian erythroblastosis virus E-26 (v-ets) oncogene related
chr18_-_84086379 1.03 ENSMUST00000060303.8
Tshz1
teashirt zinc finger family member 1
chr19_+_56461629 1.02 ENSMUST00000178590.1
ENSMUST00000039666.6
Plekhs1
pleckstrin homology domain containing, family S member 1
chr6_-_136781718 1.02 ENSMUST00000078095.6
ENSMUST00000032338.7
Gucy2c
guanylate cyclase 2c
chr2_-_176917518 1.02 ENSMUST00000108931.2
Gm14296
predicted gene 14296
chr13_-_66227573 0.99 ENSMUST00000167981.2
Gm10772
predicted gene 10772
chr11_+_114851142 0.98 ENSMUST00000133245.1
ENSMUST00000122967.2
Gprc5c
G protein-coupled receptor, family C, group 5, member C
chr9_+_53850243 0.97 ENSMUST00000048485.5
Sln
sarcolipin
chr9_+_46228580 0.96 ENSMUST00000034588.8
Apoa1
apolipoprotein A-I
chr15_+_59648644 0.96 ENSMUST00000118228.1
Trib1
tribbles homolog 1 (Drosophila)
chr11_+_70092705 0.94 ENSMUST00000124721.1
Asgr2
asialoglycoprotein receptor 2
chr4_+_98546710 0.93 ENSMUST00000102792.3
Inadl
InaD-like (Drosophila)
chr5_-_86906937 0.92 ENSMUST00000031181.9
ENSMUST00000113333.1
Ugt2b34
UDP glucuronosyltransferase 2 family, polypeptide B34
chr10_+_128908907 0.92 ENSMUST00000105229.1
Cd63
CD63 antigen
chr4_+_102254993 0.91 ENSMUST00000106908.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr7_+_101317073 0.91 ENSMUST00000163799.2
ENSMUST00000164479.2
Stard10
START domain containing 10
chr15_+_59648350 0.90 ENSMUST00000067543.6
Trib1
tribbles homolog 1 (Drosophila)
chr11_+_70092634 0.90 ENSMUST00000102572.1
Asgr2
asialoglycoprotein receptor 2
chr2_+_72054598 0.89 ENSMUST00000028525.5
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr12_+_38781093 0.88 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr13_-_12464925 0.85 ENSMUST00000124888.1
Lgals8
lectin, galactose binding, soluble 8
chr19_+_26749726 0.85 ENSMUST00000175842.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr18_+_69925466 0.85 ENSMUST00000043929.4
Ccdc68
coiled-coil domain containing 68
chr4_+_98546919 0.85 ENSMUST00000030290.7
Inadl
InaD-like (Drosophila)
chr11_+_70092653 0.85 ENSMUST00000143772.1
Asgr2
asialoglycoprotein receptor 2
chr12_+_119443410 0.84 ENSMUST00000048880.6
Macc1
metastasis associated in colon cancer 1
chr3_+_53041517 0.83 ENSMUST00000059562.7
ENSMUST00000147139.1
Lhfp
lipoma HMGIC fusion partner
chr18_+_69925542 0.83 ENSMUST00000080050.5
Ccdc68
coiled-coil domain containing 68
chr7_+_67655414 0.83 ENSMUST00000107470.1
Ttc23
tetratricopeptide repeat domain 23
chr8_-_45262012 0.82 ENSMUST00000034064.3
F11
coagulation factor XI
chr10_+_96616998 0.81 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr5_+_16553488 0.81 ENSMUST00000030683.3
Hgf
hepatocyte growth factor
chr1_+_161494649 0.79 ENSMUST00000086084.1
Tnfsf18
tumor necrosis factor (ligand) superfamily, member 18
chr6_+_134830145 0.78 ENSMUST00000046303.5
Crebl2
cAMP responsive element binding protein-like 2
chr11_+_115334731 0.77 ENSMUST00000106543.1
ENSMUST00000019006.4
Otop3
otopetrin 3
chr19_+_7056731 0.76 ENSMUST00000040261.5
Macrod1
MACRO domain containing 1
chr9_+_32224246 0.76 ENSMUST00000168954.2
Arhgap32
Rho GTPase activating protein 32
chr18_+_36528145 0.75 ENSMUST00000074298.6
ENSMUST00000115694.2
Slc4a9
solute carrier family 4, sodium bicarbonate cotransporter, member 9
chr16_-_38433145 0.75 ENSMUST00000002926.6
Pla1a
phospholipase A1 member A
chr13_+_31558157 0.75 ENSMUST00000042118.8
Foxq1
forkhead box Q1
chr4_+_97777606 0.75 ENSMUST00000075448.6
ENSMUST00000092532.6
Nfia
nuclear factor I/A
chr9_-_44802951 0.74 ENSMUST00000044694.6
Ttc36
tetratricopeptide repeat domain 36
chr3_-_69859875 0.74 ENSMUST00000051239.7
ENSMUST00000171529.1
Sptssb
serine palmitoyltransferase, small subunit B
chr18_-_60648290 0.74 ENSMUST00000143275.2
Synpo
synaptopodin
chr8_-_121083085 0.74 ENSMUST00000182264.1
Fendrr
Foxf1 adjacent non-coding developmental regulatory RNA
chr7_-_65371210 0.74 ENSMUST00000102592.3
Tjp1
tight junction protein 1
chr1_+_156838915 0.73 ENSMUST00000111720.1
Angptl1
angiopoietin-like 1
chr7_+_28825202 0.73 ENSMUST00000066264.6
Ech1
enoyl coenzyme A hydratase 1, peroxisomal
chr3_+_27154020 0.72 ENSMUST00000181124.1
1700125G22Rik
RIKEN cDNA 1700125G22 gene
chr9_+_44398176 0.72 ENSMUST00000165839.1
Slc37a4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr2_-_60722636 0.72 ENSMUST00000028348.2
ENSMUST00000112517.1
Itgb6
integrin beta 6
chr18_-_3281036 0.71 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
Crem
cAMP responsive element modulator
chr19_+_42090422 0.71 ENSMUST00000066778.4
Pi4k2a
phosphatidylinositol 4-kinase type 2 alpha
chr11_-_100146120 0.70 ENSMUST00000007317.7
Krt19
keratin 19
chr3_+_5218546 0.69 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr5_+_102481374 0.69 ENSMUST00000094559.2
ENSMUST00000073302.5
Arhgap24
Rho GTPase activating protein 24
chr4_+_11123950 0.69 ENSMUST00000142297.1
Gm11827
predicted gene 11827
chr3_-_82903963 0.68 ENSMUST00000029632.6
Lrat
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
chr17_+_29090969 0.68 ENSMUST00000119901.1
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr9_-_48835932 0.68 ENSMUST00000093852.3
Zbtb16
zinc finger and BTB domain containing 16
chr5_-_35679416 0.68 ENSMUST00000114233.2
Htra3
HtrA serine peptidase 3
chr5_-_66080971 0.67 ENSMUST00000127275.1
ENSMUST00000113724.1
Rbm47
RNA binding motif protein 47
chr5_+_92809372 0.65 ENSMUST00000113054.2
Shroom3
shroom family member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxa2_Foxa1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 25.5 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
3.3 13.3 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
2.9 20.0 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
2.1 16.7 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
1.2 6.2 GO:1904253 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
1.2 7.1 GO:0038161 prolactin signaling pathway(GO:0038161)
1.2 4.6 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
1.1 5.6 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
1.1 4.4 GO:0009441 glycolate metabolic process(GO:0009441)
1.0 3.0 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.9 17.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.8 4.8 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.7 3.5 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.7 3.4 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.6 1.9 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.6 1.7 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.6 1.7 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402) regulation of glutamine transport(GO:2000485)
0.6 2.3 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.5 1.6 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.5 4.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.5 2.6 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.5 4.6 GO:0008228 opsonization(GO:0008228)
0.5 2.4 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.5 2.3 GO:0015886 heme transport(GO:0015886)
0.5 1.4 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.4 1.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.4 2.2 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.4 1.8 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.4 1.4 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.3 2.0 GO:0036438 maintenance of lens transparency(GO:0036438)
0.3 4.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.3 9.3 GO:0017144 drug metabolic process(GO:0017144)
0.3 4.5 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.3 2.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.3 0.9 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.3 2.5 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.3 7.9 GO:0046688 response to copper ion(GO:0046688)
0.3 0.8 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.3 2.3 GO:0031179 peptide modification(GO:0031179)
0.2 0.5 GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.2 0.7 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.2 1.2 GO:0045994 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.2 0.6 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2 2.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 0.6 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.2 0.6 GO:1904868 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.2 3.2 GO:0042048 olfactory behavior(GO:0042048)
0.2 1.2 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.2 3.5 GO:0042359 vitamin D metabolic process(GO:0042359)
0.2 4.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 2.9 GO:0015874 norepinephrine transport(GO:0015874)
0.2 0.7 GO:1990401 embryonic lung development(GO:1990401)
0.2 1.5 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 0.7 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 1.4 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.2 0.5 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.2 2.4 GO:0060346 bone trabecula formation(GO:0060346)
0.2 1.0 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.2 1.0 GO:0060023 soft palate development(GO:0060023)
0.2 4.0 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.2 1.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 1.0 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.2 0.5 GO:0010159 specification of organ position(GO:0010159)
0.2 1.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 1.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.7 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.4 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.1 0.9 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.7 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.8 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 3.2 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 1.6 GO:0051132 NK T cell activation(GO:0051132)
0.1 0.4 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 1.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 1.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 1.3 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.5 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.7 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.8 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.4 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.1 0.8 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 1.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.7 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 0.2 GO:0072107 regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
0.1 0.8 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.7 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 1.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 1.3 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.6 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.2 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.1 0.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.3 GO:0046066 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.1 8.4 GO:0009166 nucleotide catabolic process(GO:0009166)
0.1 0.7 GO:0071493 cellular response to UV-B(GO:0071493)
0.1 0.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.3 GO:0090472 dibasic protein processing(GO:0090472)
0.1 1.1 GO:0060746 parental behavior(GO:0060746)
0.1 0.6 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 1.1 GO:0072189 ureter development(GO:0072189)
0.1 0.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 3.1 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.5 GO:1903849 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 6.9 GO:0007586 digestion(GO:0007586)
0.1 2.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 1.5 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.6 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 1.6 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 2.9 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.5 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.6 GO:0033572 transferrin transport(GO:0033572)
0.0 0.2 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.4 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 4.2 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 3.5 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.4 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.4 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 0.5 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.7 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.6 GO:0045109 intermediate filament organization(GO:0045109)
0.0 1.6 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 1.7 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.0 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.4 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.9 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 1.1 GO:0045851 pH reduction(GO:0045851)
0.0 0.7 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.0 40.3 GO:0006508 proteolysis(GO:0006508)
0.0 2.4 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.3 GO:0046549 retinal cone cell development(GO:0046549)
0.0 2.8 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0 0.8 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.7 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.8 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.1 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.0 0.2 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 2.6 GO:0043434 response to peptide hormone(GO:0043434)
0.0 0.2 GO:1904355 positive regulation of telomere capping(GO:1904355)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 17.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
1.1 8.9 GO:0045098 type III intermediate filament(GO:0045098)
1.0 3.0 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.9 3.8 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.6 13.9 GO:0042627 chylomicron(GO:0042627)
0.5 2.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.4 1.2 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.3 1.9 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.3 1.7 GO:0031673 H zone(GO:0031673)
0.2 0.7 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.2 0.7 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 1.6 GO:0030478 actin cap(GO:0030478)
0.2 0.9 GO:0044316 cone cell pedicle(GO:0044316)
0.2 4.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 2.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 3.6 GO:0005922 connexon complex(GO:0005922)
0.2 5.3 GO:0005771 multivesicular body(GO:0005771)
0.1 1.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 1.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 20.7 GO:0072562 blood microparticle(GO:0072562)
0.1 2.5 GO:0071564 npBAF complex(GO:0071564)
0.1 0.7 GO:0097444 spine apparatus(GO:0097444)
0.1 167.3 GO:0005615 extracellular space(GO:0005615)
0.1 0.7 GO:1990357 terminal web(GO:1990357)
0.1 0.7 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.4 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.5 GO:0000421 autophagosome membrane(GO:0000421)
0.1 3.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 3.3 GO:0005604 basement membrane(GO:0005604)
0.1 1.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 4.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.8 GO:0005581 collagen trimer(GO:0005581)
0.0 13.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 2.2 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 5.5 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 1.0 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 3.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 4.0 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.3 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0043219 lateral loop(GO:0043219)
0.0 0.7 GO:0005902 microvillus(GO:0005902)
0.0 1.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0045178 basal part of cell(GO:0045178)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.3 71.8 GO:0004556 alpha-amylase activity(GO:0004556)
2.5 7.5 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
1.9 24.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
1.8 8.9 GO:0004850 uridine phosphorylase activity(GO:0004850)
1.8 12.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.7 54.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
1.4 7.1 GO:0004925 prolactin receptor activity(GO:0004925)
1.2 3.5 GO:1902271 D3 vitamins binding(GO:1902271)
1.1 4.4 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
1.1 3.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
1.0 3.0 GO:0004923 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.8 4.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.7 7.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.6 1.8 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.6 2.3 GO:0015232 heme transporter activity(GO:0015232)
0.6 2.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.6 4.0 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.6 1.7 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.5 2.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.5 3.9 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.5 2.3 GO:0015205 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.4 2.7 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.4 19.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.4 1.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3 1.0 GO:0005118 sevenless binding(GO:0005118)
0.3 1.0 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.3 38.1 GO:0005179 hormone activity(GO:0005179)
0.3 1.4 GO:0052796 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.2 0.7 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.2 3.1 GO:1990405 protein antigen binding(GO:1990405)
0.2 0.7 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 1.4 GO:0071723 lipoteichoic acid binding(GO:0070891) lipopeptide binding(GO:0071723)
0.2 7.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.2 1.6 GO:0005534 galactose binding(GO:0005534)
0.2 0.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 0.6 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.2 2.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 1.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.2 2.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.2 0.7 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2 1.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 6.2 GO:0016709 steroid hydroxylase activity(GO:0008395) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2 2.2 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.7 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 2.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 2.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 3.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.7 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 4.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 1.9 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.3 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.1 1.5 GO:0030957 Tat protein binding(GO:0030957)
0.1 1.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 1.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 1.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 1.3 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.6 GO:0035473 lipase binding(GO:0035473)
0.1 1.0 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.5 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.4 GO:0031404 chloride ion binding(GO:0031404)
0.1 0.5 GO:0071253 connexin binding(GO:0071253)
0.1 11.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0019841 retinol binding(GO:0019841)
0.0 0.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 1.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 2.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 5.5 GO:0002020 protease binding(GO:0002020)
0.0 2.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 1.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.9 GO:0030552 cAMP binding(GO:0030552)
0.0 1.9 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.5 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.0 1.3 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 4.0 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.9 GO:0017124 SH3 domain binding(GO:0017124)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 30.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.0 PID IL27 PATHWAY IL27-mediated signaling events
0.1 1.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 23.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 6.9 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 7.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 3.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 0.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 3.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 4.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 4.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 3.0 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.9 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 1.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 2.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
1.1 19.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.6 4.6 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.6 7.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.5 13.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.5 8.9 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.5 17.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.5 6.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.4 4.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.4 7.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.3 4.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.3 3.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 5.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 4.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 2.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 8.5 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.2 2.8 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 3.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 2.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 0.7 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 4.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 4.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 4.0 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 0.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 2.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 2.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 5.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated