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GSE58827: Dynamics of the Mouse Liver

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Results for Foxd2

Z-value: 0.52

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Transcription factors associated with Foxd2

Gene Symbol Gene ID Gene Info
Foxd2
ENSMUSG00000055210.3 forkhead box D2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxd2mm10_v2_chr4_-_114908892_1149089140.298.3e-02Click!

Activity profile of Foxd2 motif

Sorted Z-values of Foxd2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_131032061 3.80 ENSMUST00000084509.3
Dmbt1
deleted in malignant brain tumors 1
chr14_+_80000292 2.29 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr2_-_62483637 2.21 ENSMUST00000136686.1
ENSMUST00000102733.3
Gcg
glucagon
chr14_-_70630149 2.08 ENSMUST00000022694.9
Dmtn
dematin actin binding protein
chr3_-_75270073 2.02 ENSMUST00000039047.4
Serpini2
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr6_+_142298419 1.99 ENSMUST00000041993.2
Iapp
islet amyloid polypeptide
chr1_-_132367879 1.90 ENSMUST00000142609.1
Tmcc2
transmembrane and coiled-coil domains 2
chr12_+_111971545 1.74 ENSMUST00000079009.5
Tdrd9
tudor domain containing 9
chr2_-_160619971 1.72 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr13_-_19824234 1.49 ENSMUST00000065335.2
Gpr141
G protein-coupled receptor 141
chr7_-_126414855 1.29 ENSMUST00000032968.5
Cd19
CD19 antigen
chr10_-_88605017 1.11 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1
myosin binding protein C, slow-type
chr3_-_145032765 1.09 ENSMUST00000029919.5
Clca3
chloride channel calcium activated 3
chr2_+_154200371 0.96 ENSMUST00000028987.6
Bpifb1
BPI fold containing family B, member 1
chr11_+_95337012 0.96 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr2_+_24345282 0.93 ENSMUST00000114485.2
Il1rn
interleukin 1 receptor antagonist
chr10_+_42860776 0.90 ENSMUST00000105494.1
Scml4
sex comb on midleg-like 4 (Drosophila)
chr1_-_37496095 0.89 ENSMUST00000148047.1
ENSMUST00000143636.1
Mgat4a
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr9_+_96258697 0.88 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chrX_+_164139321 0.87 ENSMUST00000112271.3
Ace2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr9_-_95750335 0.86 ENSMUST00000053785.3
Trpc1
transient receptor potential cation channel, subfamily C, member 1
chr19_-_31765027 0.85 ENSMUST00000065067.6
Prkg1
protein kinase, cGMP-dependent, type I
chr15_-_98607611 0.84 ENSMUST00000096224.4
Adcy6
adenylate cyclase 6
chr18_+_37504264 0.83 ENSMUST00000052179.6
Pcdhb20
protocadherin beta 20
chr10_+_67096456 0.83 ENSMUST00000174317.1
Jmjd1c
jumonji domain containing 1C
chr12_-_26456423 0.82 ENSMUST00000020970.7
Rsad2
radical S-adenosyl methionine domain containing 2
chrX_+_109196750 0.78 ENSMUST00000139259.1
ENSMUST00000060013.3
Gm6377
predicted gene 6377
chr2_+_24345305 0.77 ENSMUST00000114482.1
Il1rn
interleukin 1 receptor antagonist
chr5_-_104114088 0.77 ENSMUST00000031249.3
Sparcl1
SPARC-like 1
chrX_-_105929397 0.76 ENSMUST00000113573.1
ENSMUST00000130980.1
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chrX_+_159697308 0.75 ENSMUST00000123433.1
Sh3kbp1
SH3-domain kinase binding protein 1
chr18_+_68337504 0.73 ENSMUST00000172148.1
Mc5r
melanocortin 5 receptor
chrX_-_163761323 0.72 ENSMUST00000059320.2
Rnf138rt1
ring finger protein 138, retrogene 1
chr6_+_38918969 0.69 ENSMUST00000003017.6
Tbxas1
thromboxane A synthase 1, platelet
chr1_-_126830632 0.69 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5
NCK-associated protein 5
chr18_+_44334062 0.68 ENSMUST00000025349.5
ENSMUST00000115498.1
Myot
myotilin
chrX_+_164436987 0.67 ENSMUST00000036858.4
Asb11
ankyrin repeat and SOCS box-containing 11
chrX_+_68761839 0.67 ENSMUST00000069731.5
Fmr1nb
fragile X mental retardation 1 neighbor
chr16_-_45492962 0.67 ENSMUST00000114585.2
Gm609
predicted gene 609
chr10_+_37139558 0.64 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr12_+_38783455 0.64 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1
ets variant gene 1
chr17_-_35046726 0.63 ENSMUST00000097338.4
Msh5
mutS homolog 5 (E. coli)
chrX_+_68761875 0.61 ENSMUST00000114647.1
Fmr1nb
fragile X mental retardation 1 neighbor
chr1_-_136234113 0.59 ENSMUST00000120339.1
ENSMUST00000048668.8
5730559C18Rik
RIKEN cDNA 5730559C18 gene
chr2_-_45110336 0.57 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2
zinc finger E-box binding homeobox 2
chrX_-_105929333 0.57 ENSMUST00000134507.1
ENSMUST00000137453.1
ENSMUST00000150914.1
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr11_+_43682038 0.56 ENSMUST00000094294.4
Pwwp2a
PWWP domain containing 2A
chrX_+_107148927 0.55 ENSMUST00000147521.1
ENSMUST00000167673.1
A630033H20Rik
RIKEN cDNA A630033H20 gene
chr12_-_110840905 0.55 ENSMUST00000177224.1
ENSMUST00000084974.4
ENSMUST00000070565.8
Stk30
serine/threonine kinase 30
chr7_-_14562171 0.54 ENSMUST00000181796.1
Vmn1r90
vomeronasal 1 receptor 90
chr13_-_97747373 0.53 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr17_+_7925990 0.48 ENSMUST00000036370.7
Tagap
T cell activation Rho GTPase activating protein
chr1_+_171840607 0.47 ENSMUST00000136479.1
ENSMUST00000042302.6
Cd84
CD84 antigen
chr7_-_133015248 0.47 ENSMUST00000169570.1
Ctbp2
C-terminal binding protein 2
chr14_-_52213379 0.46 ENSMUST00000140603.1
Chd8
chromodomain helicase DNA binding protein 8
chr5_+_107497762 0.43 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr15_+_100154379 0.41 ENSMUST00000023768.6
ENSMUST00000108971.2
Dip2b
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr10_+_99443699 0.39 ENSMUST00000167243.1
Gad1-ps
glutamate decarboxylase 1, pseudogene
chr18_-_6516089 0.38 ENSMUST00000115870.2
Epc1
enhancer of polycomb homolog 1 (Drosophila)
chr11_-_107189325 0.38 ENSMUST00000018577.7
ENSMUST00000106757.1
Nol11
nucleolar protein 11
chr15_-_34678694 0.38 ENSMUST00000040791.7
Nipal2
NIPA-like domain containing 2
chr8_-_87959560 0.37 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chrX_-_105929206 0.36 ENSMUST00000134381.1
ENSMUST00000154866.1
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr1_-_18145895 0.34 ENSMUST00000026876.6
ENSMUST00000115344.1
Crisp4
cysteine-rich secretory protein 4
chr12_-_101958148 0.33 ENSMUST00000159883.1
ENSMUST00000160251.1
ENSMUST00000161011.1
ENSMUST00000021606.5
Atxn3
ataxin 3
chr6_+_136518820 0.33 ENSMUST00000032335.6
Atf7ip
activating transcription factor 7 interacting protein
chr4_-_131967824 0.32 ENSMUST00000146443.1
ENSMUST00000135579.1
Epb4.1
erythrocyte protein band 4.1
chr14_+_53875992 0.32 ENSMUST00000185111.1
Trav21-dv12
T cell receptor alpha variable 21-DV12
chr12_+_38783503 0.32 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr10_-_19011948 0.31 ENSMUST00000105527.1
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr13_+_5861489 0.29 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr10_+_57645861 0.28 ENSMUST00000177473.1
Pkib
protein kinase inhibitor beta, cAMP dependent, testis specific
chr14_+_101840501 0.28 ENSMUST00000159026.1
Lmo7
LIM domain only 7
chr11_+_105092194 0.28 ENSMUST00000021029.5
Efcab3
EF-hand calcium binding domain 3
chr6_-_16898441 0.26 ENSMUST00000031533.7
Tfec
transcription factor EC
chr3_+_108739658 0.25 ENSMUST00000133931.2
Aknad1
AKNA domain containing 1
chr3_+_89520152 0.25 ENSMUST00000000811.7
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr2_-_25608447 0.24 ENSMUST00000058137.8
Rabl6
RAB, member of RAS oncogene family-like 6
chr12_-_111980751 0.23 ENSMUST00000170525.1
BC048943
cDNA sequence BC048943
chr9_-_90270712 0.23 ENSMUST00000041767.7
ENSMUST00000144348.1
Tbc1d2b
TBC1 domain family, member 2B
chr1_-_173766876 0.23 ENSMUST00000111214.2
Ifi204
interferon activated gene 204
chr2_+_14388316 0.23 ENSMUST00000114731.1
ENSMUST00000082290.7
Slc39a12
solute carrier family 39 (zinc transporter), member 12
chr11_-_75439551 0.23 ENSMUST00000128330.1
Serpinf2
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr10_+_57645834 0.22 ENSMUST00000177325.1
Pkib
protein kinase inhibitor beta, cAMP dependent, testis specific
chr1_-_57970032 0.21 ENSMUST00000159826.1
Kctd18
potassium channel tetramerisation domain containing 18
chr14_+_26259109 0.21 ENSMUST00000174494.1
Duxbl3
double homeobox B-like 3
chr7_-_13989588 0.20 ENSMUST00000165167.1
ENSMUST00000108520.2
Sult2a4
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 4
chr7_-_102494773 0.20 ENSMUST00000058750.3
Olfr545
olfactory receptor 545
chr1_-_173912904 0.19 ENSMUST00000009340.8
Mnda
myeloid cell nuclear differentiation antigen
chr1_-_173277756 0.19 ENSMUST00000111224.3
Mptx2
mucosal pentraxin 2
chr11_+_78920787 0.19 ENSMUST00000018610.6
Nos2
nitric oxide synthase 2, inducible
chr12_+_110841021 0.18 ENSMUST00000181348.1
4921507G05Rik
RIKEN cDNA 4921507G05 gene
chr11_+_75650501 0.17 ENSMUST00000102505.3
Myo1c
myosin IC
chr14_+_53875959 0.17 ENSMUST00000180938.1
Trav21-dv12
T cell receptor alpha variable 21-DV12
chr6_-_3494587 0.16 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr6_+_11926758 0.16 ENSMUST00000133776.1
Phf14
PHD finger protein 14
chr2_+_14388434 0.16 ENSMUST00000133258.1
Slc39a12
solute carrier family 39 (zinc transporter), member 12
chr5_+_107497718 0.15 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr11_-_75439489 0.13 ENSMUST00000043696.2
Serpinf2
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr2_+_86034765 0.13 ENSMUST00000062360.4
Olfr1033
olfactory receptor 1033
chr9_-_89092835 0.12 ENSMUST00000167113.1
Trim43b
tripartite motif-containing 43B
chr19_-_53589067 0.11 ENSMUST00000095978.3
Nutf2-ps1
nuclear transport factor 2, pseudogene 1
chr1_-_126830786 0.11 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chrX_-_101269023 0.11 ENSMUST00000117736.1
Gm20489
predicted gene 20489
chr9_+_36832684 0.11 ENSMUST00000034630.8
Fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr4_-_82850721 0.10 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr18_+_73863672 0.10 ENSMUST00000134847.1
Mro
maestro
chr5_+_32247351 0.10 ENSMUST00000101376.2
Plb1
phospholipase B1
chr15_+_91231578 0.10 ENSMUST00000109284.2
CN725425
cDNA sequence CN725425
chr7_-_87493371 0.09 ENSMUST00000004770.5
Tyr
tyrosinase
chr1_-_44101982 0.09 ENSMUST00000127923.1
Tex30
testis expressed 30
chr1_-_44101661 0.09 ENSMUST00000152239.1
Tex30
testis expressed 30
chr11_+_5628738 0.09 ENSMUST00000137933.1
Ankrd36
ankyrin repeat domain 36
chr19_-_31764963 0.08 ENSMUST00000182685.1
Prkg1
protein kinase, cGMP-dependent, type I
chr19_-_8713862 0.08 ENSMUST00000010239.4
Slc3a2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr5_+_150952607 0.08 ENSMUST00000078856.6
Kl
klotho
chr10_+_11609256 0.07 ENSMUST00000052902.7
Gm9797
predicted pseudogene 9797
chr1_+_134415414 0.07 ENSMUST00000112237.1
Adipor1
adiponectin receptor 1
chr19_-_29753600 0.06 ENSMUST00000175764.1
9930021J03Rik
RIKEN cDNA 9930021J03 gene
chr2_-_73312701 0.04 ENSMUST00000058615.9
Cir1
corepressor interacting with RBPJ, 1
chr10_-_127030789 0.03 ENSMUST00000120547.1
ENSMUST00000152054.1
Tsfm
Ts translation elongation factor, mitochondrial
chr9_-_119209096 0.03 ENSMUST00000084797.4
Slc22a13
solute carrier family 22 (organic cation transporter), member 13
chr7_-_127195875 0.03 ENSMUST00000035771.3
ENSMUST00000166791.1
Cd2bp2
CD2 antigen (cytoplasmic tail) binding protein 2
chr2_-_110761564 0.03 ENSMUST00000140777.1
Ano3
anoctamin 3
chr14_+_105681824 0.02 ENSMUST00000073238.6
Gm10076
predicted gene 10076
chr2_+_9882622 0.02 ENSMUST00000114919.1
4930412O13Rik
RIKEN cDNA 4930412O13 gene
chr1_-_57970104 0.02 ENSMUST00000114410.3
Kctd18
potassium channel tetramerisation domain containing 18
chr4_-_14621805 0.02 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr17_+_34092340 0.01 ENSMUST00000025192.7
H2-Oa
histocompatibility 2, O region alpha locus
chr7_+_103731928 0.00 ENSMUST00000098193.1
Olfr628
olfactory receptor 628

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxd2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.4 1.7 GO:1901580 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.3 1.7 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.3 2.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.3 0.8 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.2 2.0 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 0.9 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.2 3.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 0.9 GO:1902608 negative regulation of inositol phosphate biosynthetic process(GO:0010920) regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.2 0.5 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.1 1.0 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.1 0.8 GO:0035811 negative regulation of urine volume(GO:0035811)
0.1 0.3 GO:0034148 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) tolerance induction to lipopolysaccharide(GO:0072573)
0.1 0.6 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.8 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 1.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.7 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 1.3 GO:0006968 cellular defense response(GO:0006968)
0.1 1.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.0 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.9 GO:0046541 saliva secretion(GO:0046541)
0.1 0.2 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.6 GO:0070431 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1 0.6 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.4 GO:0010757 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) negative regulation of plasminogen activation(GO:0010757)
0.0 2.3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.4 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.5 GO:2000270 positive regulation of transcription from RNA polymerase III promoter(GO:0045945) negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 1.9 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.0 0.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.7 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.5 2.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.4 1.7 GO:1990707 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.3 1.7 GO:0071547 piP-body(GO:0071547)
0.2 2.3 GO:0042581 specific granule(GO:0042581)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0045160 myosin I complex(GO:0045160)
0.0 1.1 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.8 GO:0031528 guanylate cyclase complex, soluble(GO:0008074) microvillus membrane(GO:0031528)
0.0 0.5 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.9 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0045352 interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353)
0.2 1.7 GO:0015616 DNA translocase activity(GO:0015616)
0.2 0.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.8 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.9 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.7 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 0.9 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 3.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.6 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.2 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.5 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 1.1 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 2.9 GO:0043621 protein self-association(GO:0043621)
0.0 4.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.2 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.0 0.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.7 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.7 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.3 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 4.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.8 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 2.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 2.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway