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GSE58827: Dynamics of the Mouse Liver

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Results for Foxo6

Z-value: 0.92

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Transcription factors associated with Foxo6

Gene Symbol Gene ID Gene Info
Foxo6
ENSMUSG00000052135.8 forkhead box O6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxo6mm10_v2_chr4_-_120287349_1202873490.618.1e-05Click!

Activity profile of Foxo6 motif

Sorted Z-values of Foxo6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_87793470 13.45 ENSMUST00000020779.4
Mpo
myeloperoxidase
chr3_-_106167564 12.04 ENSMUST00000063062.8
Chi3l3
chitinase 3-like 3
chr16_-_36408349 10.73 ENSMUST00000023619.6
Stfa2
stefin A2
chr9_+_98490522 8.48 ENSMUST00000035029.2
Rbp2
retinol binding protein 2, cellular
chr11_-_12027958 7.05 ENSMUST00000109654.1
Grb10
growth factor receptor bound protein 10
chr15_-_75111684 6.93 ENSMUST00000100542.3
Ly6c2
lymphocyte antigen 6 complex, locus C2
chr10_+_79879614 6.43 ENSMUST00000006679.8
Prtn3
proteinase 3
chr8_+_25911670 5.26 ENSMUST00000120653.1
ENSMUST00000126226.1
Kcnu1
potassium channel, subfamily U, member 1
chr13_+_76579670 4.68 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1
multiple C2 domains, transmembrane 1
chr15_-_74983430 4.57 ENSMUST00000023250.4
ENSMUST00000166694.1
Ly6i
lymphocyte antigen 6 complex, locus I
chr15_+_75268379 4.44 ENSMUST00000023247.6
Ly6f
lymphocyte antigen 6 complex, locus F
chr4_+_134510999 4.44 ENSMUST00000105866.2
Aunip
aurora kinase A and ninein interacting protein
chr16_+_17146937 4.10 ENSMUST00000115706.1
ENSMUST00000069064.4
Ydjc
YdjC homolog (bacterial)
chr12_-_91384403 3.98 ENSMUST00000141429.1
Cep128
centrosomal protein 128
chr14_-_47418407 3.95 ENSMUST00000043296.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr11_+_46235460 3.95 ENSMUST00000060185.2
Fndc9
fibronectin type III domain containing 9
chr17_+_25471564 3.72 ENSMUST00000025002.1
Tekt4
tektin 4
chr3_+_84666192 3.71 ENSMUST00000107682.1
Tmem154
transmembrane protein 154
chr11_+_69095217 3.08 ENSMUST00000101004.2
Per1
period circadian clock 1
chr5_+_110330697 3.03 ENSMUST00000112481.1
Pole
polymerase (DNA directed), epsilon
chr5_+_44100442 2.84 ENSMUST00000072800.4
Gm16401
predicted gene 16401
chr4_-_156050465 2.57 ENSMUST00000184684.1
Ttll10
tubulin tyrosine ligase-like family, member 10
chr19_-_4877882 2.57 ENSMUST00000006626.3
Actn3
actinin alpha 3
chr19_+_44293676 2.50 ENSMUST00000026221.5
Scd2
stearoyl-Coenzyme A desaturase 2
chr1_-_38664947 2.49 ENSMUST00000039827.7
ENSMUST00000027250.7
Aff3
AF4/FMR2 family, member 3
chrX_+_106920618 2.37 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr17_+_48346465 2.26 ENSMUST00000113237.3
Trem2
triggering receptor expressed on myeloid cells 2
chr2_+_148395369 2.22 ENSMUST00000109962.2
ENSMUST00000047292.2
Sstr4
somatostatin receptor 4
chr1_-_174250976 2.13 ENSMUST00000061990.4
Olfr419
olfactory receptor 419
chr2_+_91650169 2.04 ENSMUST00000090614.4
Arhgap1
Rho GTPase activating protein 1
chr3_+_96680093 1.93 ENSMUST00000130429.1
Ankrd35
ankyrin repeat domain 35
chr11_+_29463735 1.87 ENSMUST00000155854.1
Ccdc88a
coiled coil domain containing 88A
chr14_+_32166104 1.87 ENSMUST00000164341.1
Ncoa4
nuclear receptor coactivator 4
chr5_-_117389029 1.77 ENSMUST00000111953.1
ENSMUST00000086461.6
Rfc5
replication factor C (activator 1) 5
chr3_+_88381004 1.77 ENSMUST00000107540.2
Gm6821
predicted gene 6821
chr19_+_8892987 1.68 ENSMUST00000096249.5
Ints5
integrator complex subunit 5
chr11_+_54314896 1.68 ENSMUST00000072178.4
ENSMUST00000101211.2
ENSMUST00000101213.2
Acsl6
acyl-CoA synthetase long-chain family member 6
chr16_-_38800193 1.62 ENSMUST00000057767.4
Upk1b
uroplakin 1B
chr2_-_93046053 1.60 ENSMUST00000111272.1
ENSMUST00000178666.1
ENSMUST00000147339.1
Prdm11
PR domain containing 11
chr18_-_31911903 1.58 ENSMUST00000054984.6
Sft2d3
SFT2 domain containing 3
chr14_+_65605267 1.56 ENSMUST00000079469.6
Nuggc
nuclear GTPase, germinal center associated
chr1_+_136683375 1.55 ENSMUST00000181524.1
Gm19705
predicted gene, 19705
chr7_+_28440927 1.54 ENSMUST00000078845.6
Gmfg
glia maturation factor, gamma
chr3_-_27896360 1.52 ENSMUST00000058077.3
Tmem212
transmembrane protein 212
chr13_+_76579681 1.48 ENSMUST00000109589.2
Mctp1
multiple C2 domains, transmembrane 1
chr7_+_28441026 1.46 ENSMUST00000135686.1
Gmfg
glia maturation factor, gamma
chr14_-_49245389 1.42 ENSMUST00000130853.1
ENSMUST00000022398.7
1700011H14Rik
RIKEN cDNA 1700011H14 gene
chr5_+_7179299 1.34 ENSMUST00000179460.1
Tubb4b-ps1
tubulin, beta 4B class IVB, pseudogene 1
chr14_+_34170640 1.29 ENSMUST00000104925.3
Rpl23a-ps3
ribosomal protein L23A, pseudogene 3
chr17_-_57839233 1.28 ENSMUST00000095218.3
Rpl7a-ps5
ribosomal protein L7A, pseudogene 5
chr2_+_129593195 1.27 ENSMUST00000099113.3
ENSMUST00000103202.3
Sirpa
signal-regulatory protein alpha
chr5_-_65391380 1.27 ENSMUST00000120094.1
ENSMUST00000118543.1
ENSMUST00000127874.1
Rpl9
ribosomal protein L9
chr1_+_51987139 1.25 ENSMUST00000168302.1
Stat4
signal transducer and activator of transcription 4
chr5_-_65391408 1.19 ENSMUST00000057885.6
Rpl9
ribosomal protein L9
chr15_+_103453782 1.15 ENSMUST00000047405.7
Nckap1l
NCK associated protein 1 like
chr4_+_108479081 1.11 ENSMUST00000155068.1
Zcchc11
zinc finger, CCHC domain containing 11
chrX_+_134585644 1.09 ENSMUST00000113211.1
Rpl36a
ribosomal protein L36A
chr17_-_31129602 1.07 ENSMUST00000024827.4
Tff3
trefoil factor 3, intestinal
chr4_-_139131058 1.06 ENSMUST00000143971.1
Minos1
mitochondrial inner membrane organizing system 1
chrX_-_163761323 1.03 ENSMUST00000059320.2
Rnf138rt1
ring finger protein 138, retrogene 1
chr7_-_14562171 1.03 ENSMUST00000181796.1
Vmn1r90
vomeronasal 1 receptor 90
chr2_-_84425258 1.02 ENSMUST00000074262.2
Calcrl
calcitonin receptor-like
chr10_+_39420009 1.00 ENSMUST00000157009.1
Fyn
Fyn proto-oncogene
chr2_+_78051155 0.97 ENSMUST00000145972.1
4930440I19Rik
RIKEN cDNA 4930440I19 gene
chr1_-_44061936 0.93 ENSMUST00000168641.1
Gm8251
predicted gene 8251
chr12_+_108410625 0.93 ENSMUST00000109857.1
Eml1
echinoderm microtubule associated protein like 1
chr17_-_31277327 0.91 ENSMUST00000024832.7
Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr6_-_57844493 0.85 ENSMUST00000081186.3
Vmn1r21
vomeronasal 1 receptor 21
chr3_-_88548249 0.83 ENSMUST00000131775.1
ENSMUST00000008745.6
Rab25
RAB25, member RAS oncogene family
chr15_+_100154379 0.79 ENSMUST00000023768.6
ENSMUST00000108971.2
Dip2b
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr12_+_108410542 0.75 ENSMUST00000054955.7
Eml1
echinoderm microtubule associated protein like 1
chr9_-_22071345 0.70 ENSMUST00000179605.1
ENSMUST00000043922.6
Zfp653
zinc finger protein 653
chr1_-_160077918 0.69 ENSMUST00000028061.3
4930562F07Rik
RIKEN cDNA 4930562F07 gene
chrX_-_74281598 0.65 ENSMUST00000114189.2
ENSMUST00000119361.2
Dnase1l1
deoxyribonuclease 1-like 1
chrX_-_74281707 0.63 ENSMUST00000019232.3
Dnase1l1
deoxyribonuclease 1-like 1
chr6_+_57702601 0.60 ENSMUST00000072954.1
ENSMUST00000050077.8
Lancl2
LanC (bacterial lantibiotic synthetase component C)-like 2
chr7_-_107757993 0.57 ENSMUST00000052438.7
Cyb5r2
cytochrome b5 reductase 2
chr6_+_56956466 0.57 ENSMUST00000096612.3
Vmn1r4
vomeronasal 1 receptor 4
chr2_+_129592914 0.55 ENSMUST00000103203.1
Sirpa
signal-regulatory protein alpha
chr10_-_93311073 0.55 ENSMUST00000008542.5
Elk3
ELK3, member of ETS oncogene family
chr15_+_52712434 0.53 ENSMUST00000037115.7
Med30
mediator complex subunit 30
chr1_+_110099295 0.53 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr2_+_121955964 0.51 ENSMUST00000036647.6
Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr14_-_50924626 0.50 ENSMUST00000160375.1
ENSMUST00000162177.1
ENSMUST00000159292.1
Osgep
O-sialoglycoprotein endopeptidase
chr19_-_46969474 0.49 ENSMUST00000086961.7
Nt5c2
5'-nucleotidase, cytosolic II
chrX_+_112011007 0.46 ENSMUST00000131304.1
Tex16
testis expressed gene 16
chr6_+_87428986 0.44 ENSMUST00000032125.5
Bmp10
bone morphogenetic protein 10
chr6_+_57002300 0.42 ENSMUST00000079669.4
Vmn1r6
vomeronasal 1 receptor 6
chr18_-_34624562 0.41 ENSMUST00000003876.3
ENSMUST00000115766.1
ENSMUST00000097626.3
ENSMUST00000115765.1
Brd8
bromodomain containing 8
chr10_-_93310963 0.37 ENSMUST00000151153.1
Elk3
ELK3, member of ETS oncogene family
chr2_-_155357392 0.36 ENSMUST00000165234.1
ENSMUST00000077626.6
Pigu
phosphatidylinositol glycan anchor biosynthesis, class U
chr16_+_10812915 0.36 ENSMUST00000115822.1
Gm11172
predicted gene 11172
chr14_+_53683593 0.35 ENSMUST00000103663.4
Trav4-4-dv10
T cell receptor alpha variable 4-4-DV10
chr14_+_51162260 0.35 ENSMUST00000075648.3
Ear5
eosinophil-associated, ribonuclease A family, member 5
chr15_-_81843699 0.34 ENSMUST00000092020.2
Gm8444
predicted gene 8444
chr3_-_49757257 0.33 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr12_-_102423741 0.32 ENSMUST00000110020.1
Lgmn
legumain
chr7_+_84853573 0.30 ENSMUST00000078172.4
Olfr291
olfactory receptor 291
chrX_-_79358068 0.28 ENSMUST00000114021.2
Gm8787
predicted gene 8787
chr2_+_36452587 0.27 ENSMUST00000072854.1
Olfr340
olfactory receptor 340
chr5_+_88002525 0.26 ENSMUST00000031211.4
Smr3a
submaxillary gland androgen regulated protein 3A
chr11_+_99785191 0.25 ENSMUST00000105059.2
Krtap4-9
keratin associated protein 4-9
chr7_-_123369870 0.25 ENSMUST00000106442.2
ENSMUST00000098060.3
ENSMUST00000167309.1
Arhgap17
Rho GTPase activating protein 17
chr18_-_84589491 0.22 ENSMUST00000125763.1
Zfp407
zinc finger protein 407
chr18_-_12305638 0.21 ENSMUST00000122408.1
ENSMUST00000118525.1
ENSMUST00000142066.1
Ankrd29
ankyrin repeat domain 29
chr7_+_140881898 0.19 ENSMUST00000026560.7
Psmd13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr1_+_171270321 0.17 ENSMUST00000064272.3
ENSMUST00000141999.1
ENSMUST00000111313.3
B4galt3
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3
chr14_+_51451962 0.16 ENSMUST00000159611.1
ENSMUST00000159734.1
Vmn2r89
vomeronasal 2, receptor 89
chr10_-_130497379 0.15 ENSMUST00000164227.2
Vmn2r87
vomeronasal 2, receptor 87
chr3_+_103968110 0.15 ENSMUST00000117150.1
ENSMUST00000063717.7
ENSMUST00000055425.8
ENSMUST00000123611.1
ENSMUST00000090685.4
Phtf1
putative homeodomain transcription factor 1
chr3_-_127780461 0.14 ENSMUST00000029662.5
ENSMUST00000161239.1
Alpk1
alpha-kinase 1
chr4_+_156331103 0.07 ENSMUST00000074107.6
ENSMUST00000096792.5
Vmn2r-ps159
vomeronasal 2, receptor, pseudogene 159
chr7_-_9953585 0.06 ENSMUST00000165611.1
Vmn2r48
vomeronasal 2, receptor 48
chr11_+_87853207 0.05 ENSMUST00000038196.6
Mks1
Meckel syndrome, type 1
chr11_+_89073841 0.03 ENSMUST00000100619.4
Gm525
predicted gene 525

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxo6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 13.4 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
1.3 6.4 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
1.1 8.5 GO:0006776 vitamin A metabolic process(GO:0006776)
1.0 3.0 GO:0045004 DNA replication proofreading(GO:0045004)
1.0 3.0 GO:0071846 actin filament debranching(GO:0071846)
0.9 2.6 GO:1900157 regulation of fermentation(GO:0043465) regulation of bone mineralization involved in bone maturation(GO:1900157) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023)
0.8 2.3 GO:0002582 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.7 3.7 GO:0080154 regulation of fertilization(GO:0080154)
0.6 7.1 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.6 2.5 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.6 3.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.4 2.6 GO:0018094 protein polyglycylation(GO:0018094)
0.4 1.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.3 2.0 GO:1903336 endosome localization(GO:0032439) negative regulation of vacuolar transport(GO:1903336)
0.3 1.2 GO:0070358 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358)
0.3 1.7 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.3 1.0 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.2 1.8 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 1.0 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.2 0.6 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.5 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 1.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 1.6 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.3 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 1.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 1.7 GO:0016180 snRNA processing(GO:0016180)
0.1 2.4 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.4 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 10.1 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.8 GO:0031268 pseudopodium organization(GO:0031268)
0.0 2.2 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 2.5 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 6.1 GO:0007051 spindle organization(GO:0007051)
0.0 1.7 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.9 GO:0019236 response to pheromone(GO:0019236)
0.0 1.8 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.0 4.1 GO:0050821 protein stabilization(GO:0050821)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.9 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 13.4 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.6 3.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.3 2.0 GO:0097443 sorting endosome(GO:0097443)
0.3 1.8 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 4.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 3.7 GO:0097225 sperm midpiece(GO:0097225)
0.2 0.5 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.2 1.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 1.9 GO:0044754 autolysosome(GO:0044754)
0.1 1.7 GO:0032039 integrator complex(GO:0032039)
0.1 0.5 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.9 GO:0072687 meiotic spindle(GO:0072687)
0.1 1.2 GO:0031209 SCAR complex(GO:0031209)
0.1 8.4 GO:0000922 spindle pole(GO:0000922)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 10.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 2.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 3.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 5.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.4 GO:0000812 Swr1 complex(GO:0000812)
0.0 1.9 GO:0005814 centriole(GO:0005814)
0.0 2.6 GO:0005930 axoneme(GO:0005930)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 6.4 GO:0031012 extracellular matrix(GO:0031012)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.9 2.6 GO:0070737 protein-glycine ligase activity, elongating(GO:0070737)
0.6 2.5 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.6 8.5 GO:0019841 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.4 2.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.4 3.0 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.3 1.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.3 2.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.3 2.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.2 3.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 0.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 13.4 GO:0004601 peroxidase activity(GO:0004601)
0.2 1.0 GO:0042610 CD8 receptor binding(GO:0042610)
0.2 0.5 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.2 1.8 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 7.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 10.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 1.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.9 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.4 GO:0034235 GPI anchor binding(GO:0034235)
0.1 1.8 GO:0005550 pheromone binding(GO:0005550)
0.1 0.6 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.4 GO:0031433 telethonin binding(GO:0031433)
0.0 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 2.5 GO:0019843 rRNA binding(GO:0019843)
0.0 0.8 GO:0031489 myosin V binding(GO:0031489)
0.0 1.8 GO:0070888 E-box binding(GO:0070888)
0.0 1.8 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 2.6 GO:0030674 protein binding, bridging(GO:0030674)
0.0 3.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 3.4 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.2 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 2.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.8 GO:0004984 olfactory receptor activity(GO:0004984)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 14.1 PID IL23 PATHWAY IL23-mediated signaling events
0.2 3.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 7.1 PID IGF1 PATHWAY IGF1 pathway
0.1 2.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 4.0 PID AURORA A PATHWAY Aurora A signaling
0.1 7.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 6.4 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.8 PID ATR PATHWAY ATR signaling pathway
0.0 1.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.8 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.3 4.8 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.2 8.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.2 2.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 3.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 3.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 2.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins