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GSE58827: Dynamics of the Mouse Liver

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Results for Foxp2_Foxp3

Z-value: 0.63

Motif logo

Transcription factors associated with Foxp2_Foxp3

Gene Symbol Gene ID Gene Info
ENSMUSG00000029563.10 forkhead box P2
ENSMUSG00000039521.6 forkhead box P3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxp3mm10_v2_chrX_+_7580483_7580491-0.642.4e-05Click!
Foxp2mm10_v2_chr6_+_15185439_151854520.231.7e-01Click!

Activity profile of Foxp2_Foxp3 motif

Sorted Z-values of Foxp2_Foxp3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_81975742 6.03 ENSMUST00000029645.8
tryptophan 2,3-dioxygenase
chr9_+_53301571 2.99 ENSMUST00000051014.1
exophilin 5
chr1_-_130661584 2.95 ENSMUST00000137276.2
complement component 4 binding protein
chr1_-_139781236 2.93 ENSMUST00000027612.8
ENSMUST00000111989.2
ENSMUST00000111986.2
predicted gene 4788
chr1_-_162898665 2.90 ENSMUST00000111510.1
ENSMUST00000045902.6
flavin containing monooxygenase 2
chr1_-_162898484 2.79 ENSMUST00000143123.1
flavin containing monooxygenase 2
chr1_-_130661613 2.77 ENSMUST00000027657.7
complement component 4 binding protein
chr17_+_36942910 2.44 ENSMUST00000040498.5
ring finger protein 39
chr14_-_51913393 2.28 ENSMUST00000004673.7
ENSMUST00000111632.3
N-myc downstream regulated gene 2
chr4_-_19922599 2.22 ENSMUST00000029900.5
ATPase, H+ transporting, lysosomal V0 subunit D2
chr10_+_93488766 2.20 ENSMUST00000129421.1
histidine ammonia lyase
chr15_-_78468620 2.18 ENSMUST00000017086.3
transmembrane serine protease 6
chr10_+_127898515 2.15 ENSMUST00000047134.7
4short chain dehydrogenase/reductase family 9C, member 7
chr6_+_121346618 2.13 ENSMUST00000032200.9
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
chr11_+_70214105 2.12 ENSMUST00000094055.3
ENSMUST00000136328.1
ENSMUST00000126296.1
ENSMUST00000153993.2
solute carrier family 16 (monocarboxylic acid transporters), member 11
chr17_+_36943025 2.11 ENSMUST00000173072.1
ring finger protein 39
chr3_+_107230608 2.08 ENSMUST00000179399.1
RIKEN cDNA A630076J17 gene
chr14_+_55560904 2.03 ENSMUST00000072530.4
ENSMUST00000128490.1
DDB1 and CUL4 associated factor 11
chr11_+_70213910 2.00 ENSMUST00000171032.1
solute carrier family 16 (monocarboxylic acid transporters), member 11
chr11_-_84167466 1.94 ENSMUST00000050771.7
predicted gene 11437
chr12_-_103904887 1.91 ENSMUST00000074051.5
serine (or cysteine) peptidase inhibitor, clade A, member 1C
chr12_-_103773592 1.91 ENSMUST00000078869.5
serine (or cysteine) peptidase inhibitor, clade A, member 1D
chr5_+_90561102 1.79 ENSMUST00000094615.4
RIKEN cDNA 5830473C10 gene
chr14_+_55560480 1.78 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
DDB1 and CUL4 associated factor 11
chr14_+_55561060 1.75 ENSMUST00000117701.1
DDB1 and CUL4 associated factor 11
chr11_+_70054334 1.74 ENSMUST00000018699.6
ENSMUST00000108585.2
asialoglycoprotein receptor 1
chr8_-_121944886 1.71 ENSMUST00000057653.7
carbonic anhydrase 5a, mitochondrial
chr15_+_25940846 1.69 ENSMUST00000110438.1
family with sequence similarity 134, member B
chr19_+_23141183 1.69 ENSMUST00000036884.1
Kruppel-like factor 9
chr2_+_58755177 1.61 ENSMUST00000102755.3
uridine phosphorylase 2
chr7_+_140763739 1.60 ENSMUST00000026552.7
cytochrome P450, family 2, subfamily e, polypeptide 1
chr8_-_36953139 1.60 ENSMUST00000179501.1
deleted in liver cancer 1
chr2_-_148040196 1.58 ENSMUST00000136555.1
RIKEN cDNA 9030622O22 gene
chr18_-_38918642 1.57 ENSMUST00000040647.4
fibroblast growth factor 1
chr19_+_30232921 1.53 ENSMUST00000025797.5
mannose-binding lectin (protein C) 2
chr8_-_84773381 1.52 ENSMUST00000109764.1
nuclear factor I/X
chr1_+_130865669 1.50 ENSMUST00000038829.5
Fas apoptotic inhibitory molecule 3
chr12_-_103657159 1.48 ENSMUST00000044159.6
serine (or cysteine) peptidase inhibitor, clade A, member 6
chr2_+_58754910 1.47 ENSMUST00000059102.6
uridine phosphorylase 2
chr4_+_144893077 1.46 ENSMUST00000154208.1
dehydrogenase/reductase (SDR family) member 3
chr2_+_68117713 1.46 ENSMUST00000112346.2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr6_+_134830145 1.45 ENSMUST00000046303.5
cAMP responsive element binding protein-like 2
chr15_-_58214882 1.43 ENSMUST00000022986.6
F-box protein 32
chrX_+_101376359 1.41 ENSMUST00000119080.1
gap junction protein, beta 1
chr15_+_99392882 1.40 ENSMUST00000023749.8
transmembrane BAX inhibitor motif containing 6
chr11_+_114851142 1.38 ENSMUST00000133245.1
ENSMUST00000122967.2
G protein-coupled receptor, family C, group 5, member C
chr9_-_45955170 1.38 ENSMUST00000162072.1
SID1 transmembrane family, member 2
chr12_-_103657095 1.36 ENSMUST00000152517.1
serine (or cysteine) peptidase inhibitor, clade A, member 6
chr15_+_99392948 1.35 ENSMUST00000161250.1
ENSMUST00000160635.1
ENSMUST00000161778.1
transmembrane BAX inhibitor motif containing 6
chr4_+_104766334 1.35 ENSMUST00000065072.6
complement component 8, beta polypeptide
chr15_+_99393219 1.33 ENSMUST00000159209.1
transmembrane BAX inhibitor motif containing 6
chr4_+_144893127 1.32 ENSMUST00000142808.1
dehydrogenase/reductase (SDR family) member 3
chr11_+_70092634 1.31 ENSMUST00000102572.1
asialoglycoprotein receptor 2
chr5_-_87569023 1.30 ENSMUST00000113314.2
sulfotransferase family 1D, member 1
chr10_+_87859593 1.30 ENSMUST00000126490.1
insulin-like growth factor 1
chr11_+_70092705 1.29 ENSMUST00000124721.1
asialoglycoprotein receptor 2
chr12_-_103863551 1.29 ENSMUST00000085056.6
ENSMUST00000072876.5
ENSMUST00000124717.1
serine (or cysteine) peptidase inhibitor, clade A, member 1A
chr2_-_134554348 1.28 ENSMUST00000028704.2
hydroxyacid oxidase 1, liver
chr6_-_138079916 1.27 ENSMUST00000171804.1
solute carrier family 15, member 5
chr2_+_28641227 1.27 ENSMUST00000028155.5
ENSMUST00000113869.1
ENSMUST00000113867.2
tuberous sclerosis 1
chr4_+_144892813 1.26 ENSMUST00000105744.1
ENSMUST00000171001.1
dehydrogenase/reductase (SDR family) member 3
chr11_+_70092653 1.26 ENSMUST00000143772.1
asialoglycoprotein receptor 2
chr9_+_46268601 1.23 ENSMUST00000121598.1
apolipoprotein A-V
chr4_+_104766308 1.22 ENSMUST00000031663.3
complement component 8, beta polypeptide
chrX_-_139782353 1.22 ENSMUST00000101217.3
ripply1 homolog (zebrafish)
chr2_+_4718145 1.21 ENSMUST00000056914.6
BEN domain containing 7
chr11_+_78499087 1.20 ENSMUST00000017488.4
vitronectin
chr7_-_133782721 1.20 ENSMUST00000063669.1
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr6_-_124911636 1.19 ENSMUST00000032217.1
lymphocyte-activation gene 3
chr13_+_89540636 1.18 ENSMUST00000022108.7
hyaluronan and proteoglycan link protein 1
chr5_-_87254804 1.16 ENSMUST00000075858.3
UDP glucuronosyltransferase 2 family, polypeptide B37
chr15_-_5063741 1.16 ENSMUST00000110689.3
complement component 7
chr12_-_84450944 1.15 ENSMUST00000085192.5
aldehyde dehydrogenase family 6, subfamily A1
chr4_+_133553370 1.12 ENSMUST00000042706.2
nuclear receptor subfamily 0, group B, member 2
chr11_-_86993682 1.11 ENSMUST00000018571.4
yippee-like 2 (Drosophila)
chr4_-_104876383 1.11 ENSMUST00000064873.8
ENSMUST00000106808.3
ENSMUST00000048947.8
complement component 8, alpha polypeptide
chr15_-_3582596 1.09 ENSMUST00000161770.1
growth hormone receptor
chrX_-_7681034 1.08 ENSMUST00000115695.3
MAGI family member, X-linked
chr4_+_45012830 1.08 ENSMUST00000095105.1
RIKEN cDNA 1700055D18 gene
chr6_+_134830216 1.07 ENSMUST00000111937.1
cAMP responsive element binding protein-like 2
chr11_+_97685903 1.07 ENSMUST00000107583.2
CDGSH iron sulfur domain 3
chr5_-_87091150 1.05 ENSMUST00000154455.1
UDP glucuronosyltransferase 2 family, polypeptide B36
chr14_-_55560340 1.05 ENSMUST00000066106.3
RIKEN cDNA A730061H03 gene
chrX_+_139800795 1.03 ENSMUST00000054889.3
claudin 2
chr9_-_45955226 1.03 ENSMUST00000038488.9
SID1 transmembrane family, member 2
chr19_-_58455903 1.02 ENSMUST00000131877.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr1_-_179546261 1.02 ENSMUST00000027769.5
transcription factor B2, mitochondrial
chr11_-_121388186 1.02 ENSMUST00000106107.2
Rab40b, member RAS oncogene family
chr15_+_3270767 1.02 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
selenoprotein P, plasma, 1
chr7_+_113207465 0.98 ENSMUST00000047321.7
aryl hydrocarbon receptor nuclear translocator-like
chr6_+_79818031 0.98 ENSMUST00000179797.1
predicted gene, 20594
chr17_-_31144271 0.98 ENSMUST00000024826.7
trefoil factor 2 (spasmolytic protein 1)
chr10_+_60106452 0.97 ENSMUST00000165024.2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr17_+_12584183 0.97 ENSMUST00000046959.7
solute carrier family 22 (organic cation transporter), member 2
chr15_-_3583146 0.96 ENSMUST00000110698.2
growth hormone receptor
chr3_+_5218516 0.96 ENSMUST00000175866.1
zinc finger homeodomain 4
chr10_-_41579207 0.95 ENSMUST00000095227.3
coiled-coil domain containing 162
chr3_+_146597077 0.94 ENSMUST00000029837.7
ENSMUST00000121133.1
urate oxidase
chr3_+_52268337 0.92 ENSMUST00000053764.5
forkhead box O1
chr1_-_180195981 0.92 ENSMUST00000027766.6
ENSMUST00000161814.1
aarF domain containing kinase 3
chr13_-_22219820 0.91 ENSMUST00000057516.1
vomeronasal 1 receptor 193
chr18_+_5593566 0.91 ENSMUST00000160910.1
zinc finger E-box binding homeobox 1
chr10_-_18234930 0.91 ENSMUST00000052648.8
ENSMUST00000080860.6
ENSMUST00000173243.1
coiled-coil domain containing 28A
chr5_-_145879857 0.90 ENSMUST00000035918.7
cytochrome P450, family 3, subfamily a, polypeptide 11
chr19_-_58455161 0.89 ENSMUST00000135730.1
ENSMUST00000152507.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr5_+_90460889 0.87 ENSMUST00000031314.8
albumin
chr15_-_5108469 0.86 ENSMUST00000141020.1
caspase recruitment domain family, member 6
chr19_-_8218832 0.86 ENSMUST00000113298.2
solute carrier family 22. member 29
chr6_+_116650674 0.86 ENSMUST00000067354.5
ENSMUST00000178241.1
RIKEN cDNA 8430408G22 gene
chr12_-_83597140 0.85 ENSMUST00000048319.4
zinc finger, FYVE domain containing 1
chr13_+_60602182 0.85 ENSMUST00000044083.7
death associated protein kinase 1
chr3_+_138217814 0.85 ENSMUST00000090171.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chrX_-_140543177 0.84 ENSMUST00000055738.5
TSC22 domain family, member 3
chr12_-_99393010 0.84 ENSMUST00000177451.1
forkhead box N3
chr2_-_58052832 0.84 ENSMUST00000090940.5
ermin, ERM-like protein
chr10_+_87860030 0.84 ENSMUST00000062862.6
insulin-like growth factor 1
chr19_-_28963863 0.84 ENSMUST00000161813.1
RIKEN cDNA 4430402I18 gene
chr1_+_171225054 0.83 ENSMUST00000111321.1
ENSMUST00000005824.5
ENSMUST00000111320.1
ENSMUST00000111319.1
apolipoprotein A-II
chr18_-_39489157 0.83 ENSMUST00000131885.1
nuclear receptor subfamily 3, group C, member 1
chr3_+_94362444 0.83 ENSMUST00000169433.1
C2 calcium-dependent domain containing 4D
chr9_-_45954966 0.82 ENSMUST00000114573.2
SID1 transmembrane family, member 2
chr5_+_102481374 0.81 ENSMUST00000094559.2
ENSMUST00000073302.5
Rho GTPase activating protein 24
chr12_-_57546121 0.81 ENSMUST00000044380.6
forkhead box A1
chr19_-_58455398 0.80 ENSMUST00000026076.7
glial cell line derived neurotrophic factor family receptor alpha 1
chr14_-_31640878 0.80 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
2-hydroxyacyl-CoA lyase 1
chr4_+_97777606 0.80 ENSMUST00000075448.6
ENSMUST00000092532.6
nuclear factor I/A
chr19_+_4855129 0.79 ENSMUST00000119694.1
cathepsin F
chr8_+_45627946 0.79 ENSMUST00000145458.1
sorbin and SH3 domain containing 2
chr19_+_42090422 0.79 ENSMUST00000066778.4
phosphatidylinositol 4-kinase type 2 alpha
chr15_+_59648644 0.79 ENSMUST00000118228.1
tribbles homolog 1 (Drosophila)
chr19_+_31868754 0.78 ENSMUST00000075838.5
APOBEC1 complementation factor
chr6_+_30541582 0.78 ENSMUST00000096066.4
carboxypeptidase A2, pancreatic
chr15_+_59648350 0.78 ENSMUST00000067543.6
tribbles homolog 1 (Drosophila)
chr4_+_97772734 0.77 ENSMUST00000152023.1
nuclear factor I/A
chr19_-_34879452 0.76 ENSMUST00000036584.5
pantothenate kinase 1
chr6_+_51432663 0.75 ENSMUST00000005103.5
nuclear factor, erythroid derived 2, like 3
chr5_-_45450121 0.75 ENSMUST00000127562.1
quinoid dihydropteridine reductase
chr1_+_106171752 0.75 ENSMUST00000061047.6
PH domain and leucine rich repeat protein phosphatase 1
chr9_+_47530173 0.74 ENSMUST00000114548.1
ENSMUST00000152459.1
ENSMUST00000143026.1
ENSMUST00000085909.2
ENSMUST00000114547.1
ENSMUST00000034581.3
cell adhesion molecule 1
chr14_+_33941021 0.73 ENSMUST00000100720.1
growth differentiation factor 2
chr3_+_90254163 0.73 ENSMUST00000029545.8
CREB regulated transcription coactivator 2
chr5_-_87424201 0.73 ENSMUST00000072818.5
UDP glucuronosyltransferase 2 family, polypeptide B38
chr18_-_39489880 0.72 ENSMUST00000152853.1
nuclear receptor subfamily 3, group C, member 1
chr16_+_43235856 0.72 ENSMUST00000146708.1
zinc finger and BTB domain containing 20
chr5_-_77115145 0.71 ENSMUST00000081964.5
HOP homeobox
chr11_+_77765588 0.71 ENSMUST00000164315.1
myosin XVIIIA
chr1_-_139560158 0.70 ENSMUST00000160423.1
ENSMUST00000023965.5
complement factor H-related 1
chr5_+_102481546 0.70 ENSMUST00000112854.1
Rho GTPase activating protein 24
chr13_-_52929458 0.70 ENSMUST00000123599.1
AU RNA binding protein/enoyl-coenzyme A hydratase
chr15_-_5108492 0.70 ENSMUST00000118365.2
caspase recruitment domain family, member 6
chr17_-_34627365 0.70 ENSMUST00000064953.8
ENSMUST00000170345.1
ENSMUST00000171121.2
ENSMUST00000168391.2
ENSMUST00000169067.2
palmitoyl-protein thioesterase 2
chr6_+_124916863 0.70 ENSMUST00000069553.2
RIKEN cDNA A230083G16 gene
chr11_+_108395288 0.70 ENSMUST00000000049.5
apolipoprotein H
chr2_-_110305730 0.70 ENSMUST00000046233.2
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr2_+_176236860 0.69 ENSMUST00000166464.1
RIKEN cDNA 2210418O10 gene
chr11_+_119022962 0.69 ENSMUST00000026662.7
chromobox 2
chr6_-_136875794 0.69 ENSMUST00000032342.1
matrix Gla protein
chr4_-_45012093 0.68 ENSMUST00000131991.1
zinc finger and BTB domain containing 5
chr1_+_67123015 0.68 ENSMUST00000027144.7
carbamoyl-phosphate synthetase 1
chr12_-_31559969 0.68 ENSMUST00000001253.7
solute carrier family 26, member 4
chr14_-_66009204 0.68 ENSMUST00000059970.7
gulonolactone (L-) oxidase
chr3_+_5218589 0.67 ENSMUST00000177488.1
zinc finger homeodomain 4
chr8_-_25038875 0.67 ENSMUST00000084031.4
HtrA serine peptidase 4
chr11_-_106920359 0.67 ENSMUST00000167787.1
ENSMUST00000092517.2
SMAD specific E3 ubiquitin protein ligase 2
chrM_-_14060 0.67 ENSMUST00000082419.1
mitochondrially encoded NADH dehydrogenase 6
chr12_-_80968075 0.66 ENSMUST00000095572.4
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr4_+_102570065 0.66 ENSMUST00000097950.2
phosphodiesterase 4B, cAMP specific
chr6_-_138073196 0.66 ENSMUST00000050132.3
solute carrier family 15, member 5
chr11_-_100397740 0.66 ENSMUST00000001592.8
ENSMUST00000107403.1
junction plakoglobin
chr7_+_101317073 0.65 ENSMUST00000163799.2
ENSMUST00000164479.2
START domain containing 10
chr18_-_66022580 0.65 ENSMUST00000143990.1
lectin, mannose-binding, 1
chr6_+_124304646 0.65 ENSMUST00000112541.2
ENSMUST00000032234.2
CD163 antigen
chr19_+_26750939 0.65 ENSMUST00000175953.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr6_-_52640303 0.64 ENSMUST00000031788.8
3-hydroxyisobutyrate dehydrogenase
chr12_-_103738158 0.64 ENSMUST00000095450.4
serine (or cysteine) preptidase inhibitor, clade A, member 1B
chr6_-_142322978 0.64 ENSMUST00000081380.3
solute carrier organic anion transporter family, member 1a5
chr16_+_20097554 0.64 ENSMUST00000023509.3
kelch-like 24
chr1_-_153851189 0.63 ENSMUST00000059607.6
RIKEN cDNA 5830403L16 gene
chr9_-_44802951 0.63 ENSMUST00000044694.6
tetratricopeptide repeat domain 36
chr7_+_130692532 0.63 ENSMUST00000033141.6
transforming, acidic coiled-coil containing protein 2
chr3_-_146596588 0.63 ENSMUST00000029836.4
deoxyribonuclease II beta
chr2_-_176917518 0.62 ENSMUST00000108931.2
predicted gene 14296
chr10_+_62071014 0.61 ENSMUST00000053865.5
predicted gene 5424
chr6_+_53573364 0.61 ENSMUST00000047450.7
cAMP responsive element binding protein 5
chr6_-_134897815 0.60 ENSMUST00000165392.1
ENSMUST00000046255.7
ENSMUST00000111932.1
ENSMUST00000116515.2
G protein-coupled receptor 19
chr19_-_46672883 0.60 ENSMUST00000026012.7
cytochrome P450, family 17, subfamily a, polypeptide 1
chr9_-_103230415 0.59 ENSMUST00000035158.9
transferrin
chr16_+_43510267 0.59 ENSMUST00000114695.2
zinc finger and BTB domain containing 20
chr2_+_145785980 0.58 ENSMUST00000110005.1
ENSMUST00000094480.4
Ras and Rab interactor 2
chr5_-_96164147 0.58 ENSMUST00000137207.1
CCR4-NOT transcription complex, subunit 6-like
chr2_-_64975762 0.58 ENSMUST00000156765.1
growth factor receptor bound protein 14
chr15_-_50890396 0.58 ENSMUST00000185183.1
trichorhinophalangeal syndrome I (human)
chr19_-_43986552 0.58 ENSMUST00000026210.4
carboxypeptidase N, polypeptide 1
chr9_+_7272514 0.58 ENSMUST00000015394.8
matrix metallopeptidase 13
chr1_+_131970589 0.58 ENSMUST00000027695.6
solute carrier family 45, member 3
chr14_+_48120841 0.57 ENSMUST00000073150.4
pellino 2
chr7_-_25390098 0.57 ENSMUST00000054301.7
lipase, hormone sensitive
chr3_+_5218546 0.57 ENSMUST00000026284.6
zinc finger homeodomain 4
chr8_+_45627709 0.57 ENSMUST00000134321.1
ENSMUST00000135336.1
sorbin and SH3 domain containing 2
chr19_+_5877794 0.56 ENSMUST00000145200.1
ENSMUST00000025732.7
ENSMUST00000125114.1
ENSMUST00000155697.1
solute carrier family 25, member 45

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxp2_Foxp3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.9 5.7 GO:0072592 oxygen metabolic process(GO:0072592)
0.8 4.1 GO:0031438 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.6 2.4 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.6 2.3 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.5 2.1 GO:0009992 cellular water homeostasis(GO:0009992)
0.5 1.6 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.5 3.0 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.4 2.2 GO:0006548 histidine catabolic process(GO:0006548)
0.4 1.3 GO:0090649 rRNA export from nucleus(GO:0006407) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.4 1.2 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.4 2.9 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.4 3.2 GO:0033227 dsRNA transport(GO:0033227)
0.3 2.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.3 1.0 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.3 1.9 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.3 1.6 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.3 0.9 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.3 1.7 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.3 4.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 0.8 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.3 1.3 GO:0000103 sulfate assimilation(GO:0000103)
0.2 0.7 GO:0009826 unidimensional cell growth(GO:0009826)
0.2 1.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.2 4.9 GO:0042572 retinol metabolic process(GO:0042572)
0.2 0.6 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 8.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 2.1 GO:0046449 creatinine metabolic process(GO:0046449)
0.2 1.0 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.2 1.8 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 0.6 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.2 0.6 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.2 0.5 GO:0006553 lysine metabolic process(GO:0006553)
0.2 0.7 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.2 0.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 0.5 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.2 0.7 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.2 0.7 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 2.2 GO:0097264 self proteolysis(GO:0097264)
0.2 0.7 GO:1990401 embryonic lung development(GO:1990401)
0.2 0.5 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.2 1.0 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.2 1.5 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 0.5 GO:0021759 globus pallidus development(GO:0021759)
0.2 1.3 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.2 0.5 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.7 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.6 GO:0030070 insulin processing(GO:0030070)
0.1 0.6 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 0.6 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.4 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.4 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.6 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 3.3 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.1 0.1 GO:0060460 left lung morphogenesis(GO:0060460)
0.1 0.4 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.1 1.2 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.4 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.6 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.7 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.7 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 1.9 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 1.3 GO:0097421 liver regeneration(GO:0097421)
0.1 1.0 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.7 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 0.3 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1 0.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.4 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.4 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.7 GO:0002159 desmosome assembly(GO:0002159) response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1 0.5 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.1 0.8 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.4 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.1 2.9 GO:0007035 vacuolar acidification(GO:0007035)
0.1 0.4 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 1.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.5 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 1.5 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.7 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.2 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.1 0.5 GO:0034239 regulation of macrophage fusion(GO:0034239)
0.1 0.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.7 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 0.9 GO:0015747 urate transport(GO:0015747)
0.1 0.2 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.1 0.5 GO:0045994 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.1 1.0 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 0.6 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.1 0.9 GO:0071455 cellular response to hyperoxia(GO:0071455)
0.1 0.4 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 1.5 GO:0046415 urate metabolic process(GO:0046415)
0.1 1.6 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.4 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 0.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.4 GO:0008228 opsonization(GO:0008228)
0.1 0.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.5 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.3 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.1 0.4 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.7 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.1 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 1.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.5 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.2 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 0.5 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 1.6 GO:0072189 ureter development(GO:0072189)
0.1 0.3 GO:0002780 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
0.1 0.5 GO:0006083 acetate metabolic process(GO:0006083)
0.1 0.2 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.4 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.4 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 1.2 GO:0033866 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.1 0.4 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 0.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.1 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838)
0.1 1.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.6 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.2 GO:0097274 urea homeostasis(GO:0097274)
0.1 0.8 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 1.6 GO:0017144 drug metabolic process(GO:0017144)
0.1 1.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 1.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 1.0 GO:0051608 histamine transport(GO:0051608)
0.1 0.4 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.1 0.5 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.1 0.5 GO:0051013 microtubule severing(GO:0051013)
0.1 0.9 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.9 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.9 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 1.0 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.4 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.2 GO:0000189 MAPK import into nucleus(GO:0000189)
0.1 0.2 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.1 0.7 GO:0043970 histone H3-K9 acetylation(GO:0043970)
0.1 0.6 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.4 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) germline stem cell asymmetric division(GO:0098728)
0.1 0.2 GO:0090472 dibasic protein processing(GO:0090472)
0.1 0.3 GO:0006048 glucosamine metabolic process(GO:0006041) UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.5 GO:0090166 Golgi disassembly(GO:0090166)
0.1 0.7 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.4 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.4 GO:0009313 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.0 0.2 GO:0050904 diapedesis(GO:0050904)
0.0 0.7 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.4 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.5 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.3 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.2 GO:2001205 negative regulation of bone development(GO:1903011) negative regulation of osteoclast development(GO:2001205)
0.0 0.9 GO:0008272 sulfate transport(GO:0008272)
0.0 0.4 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.3 GO:0002568 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.6 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 2.4 GO:0046326 positive regulation of glucose import(GO:0046326)
0.0 0.5 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 1.8 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 1.1 GO:0046688 response to copper ion(GO:0046688)
0.0 0.3 GO:2000124 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.4 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 1.0 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.0 4.5 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.2 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.6 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:0034351 negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.3 GO:0071493 cellular response to UV-B(GO:0071493)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.4 GO:0051132 NK T cell activation(GO:0051132)
0.0 0.4 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.2 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:0072530 purine-containing compound transmembrane transport(GO:0072530)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.4 GO:1902400 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.0 0.1 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.0 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.8 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.2 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.1 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.0 0.4 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.2 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.5 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.1 GO:1901856 negative regulation of cellular respiration(GO:1901856) regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.0 0.5 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.2 GO:0072033 renal vesicle formation(GO:0072033) ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.0 0.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.5 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.6 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.0 0.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.4 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.8 GO:0019236 response to pheromone(GO:0019236)
0.0 0.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.5 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.4 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.1 GO:0060618 nipple development(GO:0060618)
0.0 0.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 1.3 GO:0006094 gluconeogenesis(GO:0006094)
0.0 2.0 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.0 GO:2000412 positive regulation of thymocyte migration(GO:2000412)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.6 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.3 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.2 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.1 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.0 0.2 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.3 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.0 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 1.1 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.4 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 1.0 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 2.1 GO:0031668 cellular response to extracellular stimulus(GO:0031668)
0.0 0.1 GO:0007468 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.1 GO:0032308 regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 1.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.4 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.4 4.8 GO:0005579 membrane attack complex(GO:0005579)
0.4 1.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.4 3.1 GO:0045098 type III intermediate filament(GO:0045098)
0.3 0.8 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.3 0.8 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.2 2.1 GO:0042567 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) insulin-like growth factor ternary complex(GO:0042567)
0.2 2.9 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2 1.2 GO:0005796 Golgi lumen(GO:0005796)
0.2 3.4 GO:0042627 chylomicron(GO:0042627)
0.2 5.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.5 GO:0044307 dendritic branch(GO:0044307)
0.1 0.4 GO:0034657 GID complex(GO:0034657)
0.1 0.8 GO:0045293 mRNA editing complex(GO:0045293)
0.1 1.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 1.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.8 GO:0033269 internode region of axon(GO:0033269)
0.1 0.3 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 0.4 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.2 GO:0044753 amphisome(GO:0044753)
0.1 0.9 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 2.1 GO:0030057 desmosome(GO:0030057)
0.1 1.5 GO:0005922 connexon complex(GO:0005922)
0.1 1.2 GO:0071564 npBAF complex(GO:0071564)
0.1 0.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 1.0 GO:0033391 chromatoid body(GO:0033391)
0.1 0.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.7 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.7 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.6 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 1.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0032300 mismatch repair complex(GO:0032300)
0.0 4.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0097227 sperm annulus(GO:0097227)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 9.3 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 3.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 2.1 GO:0042641 actomyosin(GO:0042641)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.4 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.5 GO:0031201 SNARE complex(GO:0031201)
0.0 0.5 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0097542 ciliary tip(GO:0097542)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.7 2.1 GO:0004903 growth hormone receptor activity(GO:0004903)
0.7 4.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.6 3.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.6 4.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.6 5.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.5 3.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.5 2.0 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.5 1.4 GO:0005118 sevenless binding(GO:0005118)
0.4 1.9 GO:0004883 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.4 1.5 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.4 2.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.3 1.0 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.3 2.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.3 2.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3 0.8 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.3 1.9 GO:0005534 galactose binding(GO:0005534)
0.3 0.8 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.3 1.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.3 1.0 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 0.7 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.2 1.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 0.7 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2 0.6 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2 1.0 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.2 0.5 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.2 1.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 1.1 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 2.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 0.6 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.2 0.5 GO:0019807 aspartoacylase activity(GO:0019807)
0.1 0.4 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.1 1.0 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 0.6 GO:0015154 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.5 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.8 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 1.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.5 GO:0031699 beta-3 adrenergic receptor binding(GO:0031699)
0.1 1.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.8 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.6 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.7 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 0.9 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.8 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.4 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 1.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 3.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.0 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 1.9 GO:0017166 vinculin binding(GO:0017166)
0.1 1.6 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 1.5 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.8 GO:0043426 MRF binding(GO:0043426)
0.1 4.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.1 GO:0071820 N-box binding(GO:0071820)
0.1 0.9 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 1.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.8 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 1.3 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.2 GO:0005009 insulin-activated receptor activity(GO:0005009)
0.1 0.4 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 1.0 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.6 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.1 0.7 GO:0009881 photoreceptor activity(GO:0009881)
0.1 0.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.3 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.5 GO:0031433 telethonin binding(GO:0031433)
0.1 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.1 0.1 GO:0051373 FATZ binding(GO:0051373)
0.1 1.7 GO:0001848 complement binding(GO:0001848)
0.1 1.0 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.8 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.5 GO:0034711 inhibin binding(GO:0034711)
0.1 0.4 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 1.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.6 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 0.5 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.1 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.2 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 1.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.9 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 1.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 1.6 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 6.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.5 GO:0070513 death domain binding(GO:0070513)
0.0 0.4 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.5 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.0 0.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.3 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.0 0.1 GO:0038100 nodal binding(GO:0038100)
0.0 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0090556 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.8 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.3 GO:0019841 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.0 1.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.9 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.5 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 1.2 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.3 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 1.4 GO:0038024 cargo receptor activity(GO:0038024)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 2.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0043531 ADP binding(GO:0043531)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:1990381 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) ubiquitin-specific protease binding(GO:1990381)
0.0 1.1 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.3 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 4.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.1 PID IGF1 PATHWAY IGF1 pathway
0.1 4.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 5.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 1.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.0 PID INSULIN PATHWAY Insulin Pathway
0.0 1.6 PID FGF PATHWAY FGF signaling pathway
0.0 1.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID FOXO PATHWAY FoxO family signaling
0.0 1.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 ST ADRENERGIC Adrenergic Pathway
0.0 0.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.3 6.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.3 2.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 5.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 3.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.2 1.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 2.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 7.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 3.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.4 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 0.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.9 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 3.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 2.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.1 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 1.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.1 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 1.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.8 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 3.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.1 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway