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GSE58827: Dynamics of the Mouse Liver

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Results for Fubp1

Z-value: 0.60

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Transcription factors associated with Fubp1

Gene Symbol Gene ID Gene Info
Fubp1
ENSMUSG00000028034.9 far upstream element (FUSE) binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Fubp1mm10_v2_chr3_+_152210458_1522105340.335.0e-02Click!

Activity profile of Fubp1 motif

Sorted Z-values of Fubp1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_21780616 3.27 ENSMUST00000080511.2
Hist1h1b
histone cluster 1, H1b
chr11_+_44617310 2.86 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1
early B cell factor 1
chr2_+_103970115 2.19 ENSMUST00000111143.1
ENSMUST00000138815.1
Lmo2
LIM domain only 2
chr2_+_103969528 2.03 ENSMUST00000123437.1
ENSMUST00000163256.1
Lmo2
LIM domain only 2
chr2_+_103970221 1.97 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2
LIM domain only 2
chr10_-_88605017 1.94 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1
myosin binding protein C, slow-type
chr9_-_112187766 1.83 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr2_-_32353247 1.64 ENSMUST00000078352.5
ENSMUST00000113352.2
ENSMUST00000113365.1
Dnm1
dynamin 1
chr11_+_67277124 1.60 ENSMUST00000019625.5
Myh8
myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr2_-_32353283 1.59 ENSMUST00000091089.5
ENSMUST00000113350.1
Dnm1
dynamin 1
chr12_+_109545390 1.55 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr11_+_24076529 1.44 ENSMUST00000148087.1
Gm12063
predicted gene 12063
chr2_-_151009364 1.38 ENSMUST00000109896.1
Ninl
ninein-like
chr1_+_156366037 1.29 ENSMUST00000102782.3
Gm2000
predicted gene 2000
chr19_-_47692042 1.23 ENSMUST00000026045.7
ENSMUST00000086923.5
Col17a1
collagen, type XVII, alpha 1
chr11_+_96282648 1.10 ENSMUST00000168043.1
Hoxb8
homeobox B8
chr4_+_123282778 1.09 ENSMUST00000106243.1
ENSMUST00000106241.1
ENSMUST00000080178.6
Pabpc4
poly(A) binding protein, cytoplasmic 4
chr7_-_110862944 1.07 ENSMUST00000033050.3
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr18_-_70141568 1.06 ENSMUST00000121693.1
Rab27b
RAB27b, member RAS oncogene family
chr9_-_112187898 1.01 ENSMUST00000178410.1
ENSMUST00000172380.3
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr18_-_34751502 1.01 ENSMUST00000060710.7
Cdc25c
cell division cycle 25C
chr5_+_13399309 0.95 ENSMUST00000030714.7
ENSMUST00000141968.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr11_+_67200052 0.93 ENSMUST00000124516.1
ENSMUST00000018637.8
Myh1
myosin, heavy polypeptide 1, skeletal muscle, adult
chr4_-_147642496 0.93 ENSMUST00000133006.1
ENSMUST00000037565.7
ENSMUST00000105720.1
2610305D13Rik
RIKEN cDNA 2610305D13 gene
chr8_+_93810832 0.93 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1
guanine nucleotide binding protein, alpha O
chr10_+_14523062 0.89 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr5_+_110839973 0.88 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr16_-_92826004 0.87 ENSMUST00000023673.7
Runx1
runt related transcription factor 1
chr2_-_72813665 0.86 ENSMUST00000136807.1
ENSMUST00000148327.1
6430710C18Rik
RIKEN cDNA 6430710C18 gene
chr14_+_11227511 0.86 ENSMUST00000080237.3
Rpl21-ps4
ribosomal protein L21, pseudogene 4
chrX_-_59567348 0.86 ENSMUST00000124402.1
Fgf13
fibroblast growth factor 13
chrX_-_59568068 0.83 ENSMUST00000119833.1
ENSMUST00000131319.1
Fgf13
fibroblast growth factor 13
chr5_-_69542622 0.83 ENSMUST00000031045.6
Yipf7
Yip1 domain family, member 7
chr3_-_109027600 0.81 ENSMUST00000171143.1
Fam102b
family with sequence similarity 102, member B
chrX_-_106485214 0.80 ENSMUST00000039447.7
Fndc3c1
fibronectin type III domain containing 3C1
chr11_+_104550663 0.80 ENSMUST00000018800.2
Myl4
myosin, light polypeptide 4
chr11_+_96282529 0.80 ENSMUST00000125410.1
Hoxb8
homeobox B8
chr5_+_62813823 0.77 ENSMUST00000170704.1
Gm17384
predicted gene, 17384
chr6_-_135118240 0.77 ENSMUST00000032327.7
ENSMUST00000111922.1
Gprc5d
G protein-coupled receptor, family C, group 5, member D
chr7_-_116084635 0.77 ENSMUST00000111755.3
Gm4353
predicted gene 4353
chr3_+_87906321 0.74 ENSMUST00000005017.8
Hdgf
hepatoma-derived growth factor
chr6_-_129533267 0.74 ENSMUST00000181594.1
1700101I11Rik
RIKEN cDNA 1700101I11 gene
chr14_-_98169542 0.69 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1
dachshund 1 (Drosophila)
chr10_+_53596936 0.68 ENSMUST00000020004.6
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr12_-_32208609 0.65 ENSMUST00000053215.7
Pik3cg
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr12_+_69963452 0.61 ENSMUST00000110560.1
Gm3086
predicted gene 3086
chr18_+_34751803 0.61 ENSMUST00000181453.1
ENSMUST00000181641.1
2010110K18Rik
RIKEN cDNA 2010110K18 gene
chr5_+_120589003 0.59 ENSMUST00000069259.2
Iqcd
IQ motif containing D
chr2_-_127729872 0.59 ENSMUST00000028856.2
Mall
mal, T cell differentiation protein-like
chr11_-_68973840 0.59 ENSMUST00000038644.4
Rangrf
RAN guanine nucleotide release factor
chr10_-_128549102 0.58 ENSMUST00000176906.1
Rpl41
ribosomal protein L41
chr12_-_83984849 0.58 ENSMUST00000164935.2
Gm17673
predicted gene, 17673
chr5_-_135394499 0.57 ENSMUST00000065638.4
ENSMUST00000111171.2
Pom121
nuclear pore membrane protein 121
chr9_-_61372187 0.55 ENSMUST00000098658.2
Gm10655
predicted gene 10655
chr2_-_69206146 0.55 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr17_-_24527925 0.55 ENSMUST00000176652.1
Traf7
TNF receptor-associated factor 7
chr17_-_24527830 0.54 ENSMUST00000176353.1
ENSMUST00000176237.1
Traf7
TNF receptor-associated factor 7
chrX_+_163911401 0.54 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr18_-_77767752 0.54 ENSMUST00000048192.7
Haus1
HAUS augmin-like complex, subunit 1
chr3_+_87906842 0.52 ENSMUST00000159492.1
Hdgf
hepatoma-derived growth factor
chr7_+_58658181 0.51 ENSMUST00000168747.1
Atp10a
ATPase, class V, type 10A
chr5_-_124354671 0.51 ENSMUST00000031341.4
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr11_-_102319093 0.50 ENSMUST00000174302.1
ENSMUST00000178839.1
ENSMUST00000006754.7
Ubtf
upstream binding transcription factor, RNA polymerase I
chr18_+_35536539 0.48 ENSMUST00000081864.3
Gm5239
predicted pseudogene 5239
chrX_+_94636066 0.48 ENSMUST00000096368.3
Gspt2
G1 to S phase transition 2
chr17_+_35049966 0.47 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chr19_+_53140430 0.46 ENSMUST00000111741.2
Add3
adducin 3 (gamma)
chr2_-_156992021 0.44 ENSMUST00000109558.1
ENSMUST00000069600.6
ENSMUST00000072298.6
Ndrg3
N-myc downstream regulated gene 3
chr2_+_104069819 0.43 ENSMUST00000111131.2
ENSMUST00000111132.1
ENSMUST00000129749.1
Cd59b
CD59b antigen
chr17_+_27057288 0.42 ENSMUST00000049308.8
Itpr3
inositol 1,4,5-triphosphate receptor 3
chr6_+_134920401 0.41 ENSMUST00000067327.4
ENSMUST00000003115.6
Cdkn1b
cyclin-dependent kinase inhibitor 1B
chr9_+_109875541 0.41 ENSMUST00000094324.3
Cdc25a
cell division cycle 25A
chr4_+_147361303 0.41 ENSMUST00000133078.1
ENSMUST00000154154.1
Gm13145
predicted gene 13145
chr4_-_94650092 0.40 ENSMUST00000107101.1
Lrrc19
leucine rich repeat containing 19
chr6_+_83165920 0.39 ENSMUST00000077407.5
ENSMUST00000113913.1
ENSMUST00000130212.1
Dctn1
dynactin 1
chr3_+_122924353 0.38 ENSMUST00000106429.3
1810037I17Rik
RIKEN cDNA 1810037I17 gene
chr5_-_73632421 0.38 ENSMUST00000087177.2
Lrrc66
leucine rich repeat containing 66
chr14_+_51129055 0.37 ENSMUST00000095923.3
Rnase6
ribonuclease, RNase A family, 6
chr1_-_173277756 0.37 ENSMUST00000111224.3
Mptx2
mucosal pentraxin 2
chr2_+_111378967 0.37 ENSMUST00000062407.2
Olfr1284
olfactory receptor 1284
chr19_+_4192129 0.34 ENSMUST00000046094.4
Ppp1ca
protein phosphatase 1, catalytic subunit, alpha isoform
chr10_-_53630439 0.33 ENSMUST00000075540.5
Mcm9
minichromosome maintenance complex component 9
chr2_-_45110336 0.33 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2
zinc finger E-box binding homeobox 2
chr2_-_69206133 0.32 ENSMUST00000112320.1
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr3_+_84952146 0.32 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr17_-_44736648 0.30 ENSMUST00000113572.2
Runx2
runt related transcription factor 2
chr11_+_99857915 0.30 ENSMUST00000107434.1
Gm11568
predicted gene 11568
chr4_-_11965699 0.30 ENSMUST00000108301.1
ENSMUST00000095144.3
ENSMUST00000108302.1
Pdp1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr2_+_10372426 0.29 ENSMUST00000114864.2
ENSMUST00000116594.2
ENSMUST00000041105.6
Sfmbt2
Scm-like with four mbt domains 2
chr13_-_78196373 0.29 ENSMUST00000125176.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr18_-_31911903 0.28 ENSMUST00000054984.6
Sft2d3
SFT2 domain containing 3
chr5_+_147430153 0.28 ENSMUST00000031651.8
Pan3
PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr13_-_96435952 0.28 ENSMUST00000181761.1
Ankdd1b
ankyrin repeat and death domain containing 1B
chr19_-_40994133 0.26 ENSMUST00000117695.1
Blnk
B cell linker
chr1_-_154725920 0.25 ENSMUST00000004214.8
Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr1_+_34005872 0.25 ENSMUST00000182296.1
Dst
dystonin
chr4_+_109343029 0.24 ENSMUST00000030281.5
Eps15
epidermal growth factor receptor pathway substrate 15
chr6_+_17307632 0.24 ENSMUST00000115453.1
Cav1
caveolin 1, caveolae protein
chr4_-_55532453 0.23 ENSMUST00000132746.1
ENSMUST00000107619.2
Klf4
Kruppel-like factor 4 (gut)
chr8_+_66386292 0.22 ENSMUST00000039540.5
ENSMUST00000110253.2
March1
membrane-associated ring finger (C3HC4) 1
chr17_+_26252903 0.22 ENSMUST00000025023.7
Luc7l
Luc7 homolog (S. cerevisiae)-like
chr5_+_48242549 0.21 ENSMUST00000172493.1
Slit2
slit homolog 2 (Drosophila)
chr12_-_91590009 0.21 ENSMUST00000021345.6
Gtf2a1
general transcription factor II A, 1
chr1_+_107361929 0.21 ENSMUST00000027566.2
Serpinb11
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
chr15_+_77084367 0.20 ENSMUST00000181870.1
1700109K24Rik
RIKEN cDNA 1700109K24 gene
chr7_+_75643223 0.20 ENSMUST00000137959.1
Akap13
A kinase (PRKA) anchor protein 13
chr1_+_153905301 0.20 ENSMUST00000105679.3
A930039A15Rik
RIKEN cDNA A930039A15 gene
chr11_+_4895328 0.20 ENSMUST00000038237.1
Thoc5
THO complex 5
chr2_+_65845767 0.20 ENSMUST00000122912.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr11_+_4895316 0.19 ENSMUST00000101615.2
Thoc5
THO complex 5
chr12_+_3365108 0.18 ENSMUST00000020999.5
Kif3c
kinesin family member 3C
chr12_+_87954475 0.18 ENSMUST00000181843.1
ENSMUST00000180706.1
ENSMUST00000181394.1
ENSMUST00000110145.4
ENSMUST00000181326.1
ENSMUST00000181300.1
Gm2042
predicted gene 2042
chrX_-_103623648 0.18 ENSMUST00000156211.1
Ftx
Ftx transcript, Xist regulator (non-protein coding)
chr2_+_88817173 0.17 ENSMUST00000072057.1
Olfr1202
olfactory receptor 1202
chr18_+_86711059 0.17 ENSMUST00000068423.3
Cbln2
cerebellin 2 precursor protein
chr9_+_61372359 0.17 ENSMUST00000178113.1
ENSMUST00000159386.1
Tle3
transducin-like enhancer of split 3, homolog of Drosophila E(spl)
chrX_-_103623704 0.16 ENSMUST00000130063.1
ENSMUST00000125419.1
Ftx
Ftx transcript, Xist regulator (non-protein coding)
chr19_-_56548013 0.16 ENSMUST00000182059.1
Dclre1a
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
chr19_-_56548122 0.16 ENSMUST00000026063.5
ENSMUST00000182276.1
Dclre1a
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
chr1_-_134955908 0.16 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr7_+_103184803 0.16 ENSMUST00000106893.1
Olfr592
olfactory receptor 592
chr15_+_78983041 0.15 ENSMUST00000109687.1
ENSMUST00000109688.1
ENSMUST00000130663.2
Triobp
TRIO and F-actin binding protein
chr19_+_44562841 0.15 ENSMUST00000040455.4
Hif1an
hypoxia-inducible factor 1, alpha subunit inhibitor
chr13_+_119462752 0.15 ENSMUST00000026519.8
4833420G17Rik
RIKEN cDNA 4833420G17 gene
chr3_+_14480692 0.15 ENSMUST00000037321.7
ENSMUST00000120484.1
ENSMUST00000120801.1
Slc7a12
solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr4_-_94650134 0.14 ENSMUST00000053419.2
Lrrc19
leucine rich repeat containing 19
chr3_+_96629919 0.14 ENSMUST00000048915.6
Rbm8a
RNA binding motif protein 8a
chr10_+_94576254 0.13 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr14_+_61599493 0.12 ENSMUST00000039562.6
Trim13
tripartite motif-containing 13
chr19_+_8617991 0.12 ENSMUST00000010250.2
Slc22a6
solute carrier family 22 (organic anion transporter), member 6
chr5_-_110269816 0.11 ENSMUST00000059229.9
ENSMUST00000112505.2
Pgam5
phosphoglycerate mutase family member 5
chr9_+_106821874 0.11 ENSMUST00000159645.1
Vprbp
Vpr (HIV-1) binding protein
chr1_-_138175126 0.11 ENSMUST00000183301.1
Ptprc
protein tyrosine phosphatase, receptor type, C
chr1_-_138175238 0.11 ENSMUST00000182536.1
Ptprc
protein tyrosine phosphatase, receptor type, C
chr4_+_133369702 0.10 ENSMUST00000030669.7
Slc9a1
solute carrier family 9 (sodium/hydrogen exchanger), member 1
chr17_-_27204357 0.10 ENSMUST00000055117.7
Lemd2
LEM domain containing 2
chr17_+_26252915 0.10 ENSMUST00000114976.2
ENSMUST00000140427.1
ENSMUST00000119928.1
Luc7l
Luc7 homolog (S. cerevisiae)-like
chr5_+_66968416 0.10 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr19_+_12798574 0.09 ENSMUST00000025601.6
Lpxn
leupaxin
chr12_+_35925620 0.09 ENSMUST00000042101.4
ENSMUST00000154042.1
Agr3
anterior gradient 3
chr1_+_174430430 0.09 ENSMUST00000053178.4
Olfr414
olfactory receptor 414
chr5_-_5266038 0.08 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
Cdk14
cyclin-dependent kinase 14
chr4_-_118409219 0.08 ENSMUST00000075406.5
Szt2
seizure threshold 2
chr2_-_151476153 0.08 ENSMUST00000080132.2
4921509C19Rik
RIKEN cDNA 4921509C19 gene
chr10_+_39420009 0.08 ENSMUST00000157009.1
Fyn
Fyn proto-oncogene
chr5_-_145010643 0.07 ENSMUST00000110673.1
Kpna7
karyopherin alpha 7 (importin alpha 8)
chr5_-_32854185 0.07 ENSMUST00000130134.2
ENSMUST00000120129.2
Prr14l
proline rich 14-like
chr2_-_42653598 0.07 ENSMUST00000052550.6
Lrp1b
low density lipoprotein-related protein 1B (deleted in tumors)
chr10_-_33624587 0.07 ENSMUST00000160299.1
ENSMUST00000019920.6
Clvs2
clavesin 2
chr3_+_138352378 0.07 ENSMUST00000090166.4
Adh6b
alcohol dehydrogenase 6B (class V)
chr5_+_135369942 0.06 ENSMUST00000000940.8
Nsun5
NOL1/NOP2/Sun domain family, member 5
chr8_+_21938352 0.06 ENSMUST00000076786.2
Defb35
defensin beta 35
chr2_+_104590453 0.06 ENSMUST00000028599.7
Cstf3
cleavage stimulation factor, 3' pre-RNA, subunit 3
chr11_-_69681903 0.05 ENSMUST00000066760.1
Senp3
SUMO/sentrin specific peptidase 3
chr5_+_88487982 0.05 ENSMUST00000031222.8
Enam
enamelin
chr5_+_122391878 0.04 ENSMUST00000102525.4
Arpc3
actin related protein 2/3 complex, subunit 3
chr4_+_146514920 0.04 ENSMUST00000140089.1
ENSMUST00000179175.1
Gm13247
predicted gene 13247
chr7_+_6961160 0.03 ENSMUST00000054055.6
Usp29
ubiquitin specific peptidase 29
chr15_+_102954427 0.03 ENSMUST00000001701.3
Hoxc11
homeobox C11
chr1_-_134955847 0.03 ENSMUST00000168381.1
Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr4_+_118409331 0.02 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
Med8
mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)
chr10_+_50895651 0.02 ENSMUST00000020071.3
Sim1
single-minded homolog 1 (Drosophila)
chr9_+_88839164 0.02 ENSMUST00000163255.2
Trim43c
tripartite motif-containing 43C
chr8_-_60954726 0.01 ENSMUST00000110302.1
Clcn3
chloride channel 3
chr16_-_94370647 0.01 ENSMUST00000113910.1
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr7_+_31059342 0.01 ENSMUST00000039775.7
Lgi4
leucine-rich repeat LGI family, member 4
chr11_-_107348130 0.01 ENSMUST00000134763.1
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr4_-_101893789 0.01 ENSMUST00000051043.3
C130073F10Rik
RIKEN cDNA C130073F10 gene
chr6_-_113377510 0.01 ENSMUST00000099118.2
Tada3
transcriptional adaptor 3
chr2_+_65845833 0.00 ENSMUST00000053910.3
Csrnp3
cysteine-serine-rich nuclear protein 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Fubp1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.4 6.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.3 0.9 GO:0098763 mitotic cell cycle phase(GO:0098763)
0.3 0.9 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.3 2.3 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.2 1.0 GO:1903375 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.2 1.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.2 0.5 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.7 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 1.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.6 GO:0030049 muscle filament sliding(GO:0030049)
0.1 0.7 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.6 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.1 1.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.9 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.4 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.6 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.2 GO:0071676 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 0.4 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.3 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 0.4 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.1 1.1 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 0.4 GO:0001905 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.1 0.2 GO:0014900 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.1 0.5 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.1 0.3 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 1.5 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.3 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.5 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.2 GO:2000473 immunoglobulin biosynthetic process(GO:0002378) regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.0 1.4 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.3 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 2.8 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.6 GO:0006999 nuclear pore organization(GO:0006999)
0.0 3.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.8 GO:0031424 keratinization(GO:0031424)
0.0 0.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.1 GO:0044821 telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.6 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.4 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.0 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) regulation of enamel mineralization(GO:0070173)
0.0 1.0 GO:0061515 myeloid cell development(GO:0061515)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.2 0.6 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 0.5 GO:0018444 translation release factor complex(GO:0018444)
0.1 1.6 GO:0032982 myosin filament(GO:0032982)
0.1 0.9 GO:0031262 Ndc80 complex(GO:0031262)
0.1 3.2 GO:0043196 varicosity(GO:0043196)
0.1 2.9 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 1.5 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.5 GO:0070652 HAUS complex(GO:0070652)
0.1 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 3.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 1.0 GO:0031672 A band(GO:0031672)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 2.0 GO:0014704 intercalated disc(GO:0014704)
0.0 1.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 1.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 7.0 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 0.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 2.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 6.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.9 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.5 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.2 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.5 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 1.6 GO:0000146 microfilament motor activity(GO:0000146)
0.1 0.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 1.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 1.1 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 2.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.1 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0050733 RS domain binding(GO:0050733)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.0 GO:0050699 WW domain binding(GO:0050699)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0031404 chloride ion binding(GO:0031404)
0.0 2.5 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 0.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 2.3 PID ATM PATHWAY ATM pathway
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 1.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 3.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 4.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.4 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 3.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases