GSE58827: Dynamics of the Mouse Liver

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• FOV table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
Gli3 Links Ensembl NCBI MGI UniProt	ENSMUSG00000021318.9	GLI-Kruppel family member GLI3
Zic1 Links Ensembl NCBI MGI UniProt	ENSMUSG00000032368.8	zinc finger protein of the cerebellum 1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Gli3	mm10_v2_chr13_+_15463837_15463980	0.81	2.0e-09	Click!
Zic1	mm10_v2_chr9_-_91365778_91365815	0.49	2.5e-03	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr7_-_142657466 Show fit	14.08	ENSMUST00000097936.2 ENSMUST00000000033.5	Igf2 Links Ensembl NCBI MGI UniProt Show fit	insulin-like growth factor 2
chr12_+_109453455 Show fit	12.87	ENSMUST00000109844.4 ENSMUST00000109842.2 ENSMUST00000109843.1 ENSMUST00000109846.4 ENSMUST00000173539.1 ENSMUST00000109841.2	Dlk1 Links Ensembl NCBI MGI UniProt Show fit	delta-like 1 homolog (Drosophila)
chr11_+_72999069 Show fit	11.20	ENSMUST00000021141.7	P2rx1 Links Ensembl NCBI MGI UniProt Show fit	purinergic receptor P2X, ligand-gated ion channel, 1
chr7_+_24370255 Show fit	11.11	ENSMUST00000171904.1	Kcnn4 Links Ensembl NCBI MGI UniProt Show fit	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr6_+_30738044 Show fit	9.34	ENSMUST00000128398.1 ENSMUST00000163949.2 ENSMUST00000124665.1	Mest Links Ensembl NCBI MGI UniProt Show fit	mesoderm specific transcript
chr11_-_102365111 Show fit	9.10	ENSMUST00000006749.9	Slc4a1 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 4 (anion exchanger), member 1
chr2_+_157560078 Show fit	9.03	ENSMUST00000153739.2 ENSMUST00000173595.1 ENSMUST00000109526.1 ENSMUST00000173839.1 ENSMUST00000173041.1 ENSMUST00000173793.1 ENSMUST00000172487.1 ENSMUST00000088484.5	Nnat Links Ensembl NCBI MGI UniProt Show fit	neuronatin
chr6_+_113531675 Show fit	8.81	ENSMUST00000036340.5 ENSMUST00000101051.2	Fancd2 Links Ensembl NCBI MGI UniProt Show fit	Fanconi anemia, complementation group D2
chr9_-_103480328 Show fit	7.53	ENSMUST00000124310.2	Bfsp2 Links Ensembl NCBI MGI UniProt Show fit	beaded filament structural protein 2, phakinin
chr12_+_109540979 Show fit	7.40	ENSMUST00000129245.1 ENSMUST00000143836.1 ENSMUST00000124106.1	Meg3 Links Ensembl NCBI MGI UniProt Show fit	maternally expressed 3
chr7_-_142656018 Show fit	6.94	ENSMUST00000178921.1	Igf2 Links Ensembl NCBI MGI UniProt Show fit	insulin-like growth factor 2
chr12_+_109545390 Show fit	6.65	ENSMUST00000146701.1	Meg3 Links Ensembl NCBI MGI UniProt Show fit	maternally expressed 3
chr13_+_44729535 Show fit	6.43	ENSMUST00000174068.1	Jarid2 Links Ensembl NCBI MGI UniProt Show fit	jumonji, AT rich interactive domain 2
chr18_-_78142119 Show fit	5.80	ENSMUST00000160639.1	Slc14a1 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 14 (urea transporter), member 1
chr7_-_24760311 Show fit	5.47	ENSMUST00000063956.5	Cd177 Links Ensembl NCBI MGI UniProt Show fit	CD177 antigen
chr8_+_23139064 Show fit	5.41	ENSMUST00000033947.8	Ank1 Links Ensembl NCBI MGI UniProt Show fit	ankyrin 1, erythroid
chr4_-_68954351 Show fit	5.32	ENSMUST00000030036.5	Brinp1 Links Ensembl NCBI MGI UniProt Show fit	bone morphogenic protein/retinoic acid inducible neural specific 1
chr11_+_11684967 Show fit	5.04	ENSMUST00000126058.1 ENSMUST00000141436.1	Ikzf1 Links Ensembl NCBI MGI UniProt Show fit	IKAROS family zinc finger 1
chr8_+_23139030 Show fit	4.94	ENSMUST00000121075.1	Ank1 Links Ensembl NCBI MGI UniProt Show fit	ankyrin 1, erythroid
chr10_-_127341583 Show fit	4.42	ENSMUST00000026474.3	Gli1 Links Ensembl NCBI MGI UniProt Show fit	GLI-Kruppel family member GLI1
chrX_-_7574120 Show fit	4.22	ENSMUST00000045924.7 ENSMUST00000115742.2 ENSMUST00000150787.1	Ppp1r3f Links Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr11_+_101176041 Show fit	4.05	ENSMUST00000103109.3	Cntnap1 Links Ensembl NCBI MGI UniProt Show fit	contactin associated protein-like 1
chr1_-_133801031 Show fit	4.05	ENSMUST00000143567.1	Atp2b4 Links Ensembl NCBI MGI UniProt Show fit	ATPase, Ca++ transporting, plasma membrane 4
chr4_-_148130678 Show fit	3.84	ENSMUST00000030862.4	Draxin Links Ensembl NCBI MGI UniProt Show fit	dorsal inhibitory axon guidance protein
chr7_+_99268338 Show fit	3.68	ENSMUST00000107100.2	Map6 Links Ensembl NCBI MGI UniProt Show fit	microtubule-associated protein 6
chr11_+_72042455 Show fit	3.67	ENSMUST00000021164.3	Fam64a Links Ensembl NCBI MGI UniProt Show fit	family with sequence similarity 64, member A
chr13_-_117025505 Show fit	3.66	ENSMUST00000022239.6	Parp8 Links Ensembl NCBI MGI UniProt Show fit	poly (ADP-ribose) polymerase family, member 8
chr17_+_25366550 Show fit	3.66	ENSMUST00000069616.7	Tpsb2 Links Ensembl NCBI MGI UniProt Show fit	tryptase beta 2
chr18_-_35662180 Show fit	3.65	ENSMUST00000025209.4 ENSMUST00000096573.2	Spata24 Links Ensembl NCBI MGI UniProt Show fit	spermatogenesis associated 24
chr10_-_79788924 Show fit	3.62	ENSMUST00000020573.6	Prss57 Links Ensembl NCBI MGI UniProt Show fit	protease, serine 57
chr15_-_103310425 Show fit	3.61	ENSMUST00000079824.4	Gpr84 Links Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor 84
chr15_-_100669496 Show fit	3.56	ENSMUST00000182814.1 ENSMUST00000182068.1	Bin2 Links Ensembl NCBI MGI UniProt Show fit	bridging integrator 2
chr2_-_150668198 Show fit	3.54	ENSMUST00000028944.3	Acss1 Links Ensembl NCBI MGI UniProt Show fit	acyl-CoA synthetase short-chain family member 1
chr15_-_100669512 Show fit	3.51	ENSMUST00000182574.1 ENSMUST00000182775.1	Bin2 Links Ensembl NCBI MGI UniProt Show fit	bridging integrator 2
chr4_-_83021102 Show fit	3.46	ENSMUST00000071708.5	Frem1 Links Ensembl NCBI MGI UniProt Show fit	Fras1 related extracellular matrix protein 1
chrX_-_7964166 Show fit	3.44	ENSMUST00000128449.1	Gata1 Links Ensembl NCBI MGI UniProt Show fit	GATA binding protein 1
chr8_-_71723308 Show fit	3.42	ENSMUST00000125092.1	Fcho1 Links Ensembl NCBI MGI UniProt Show fit	FCH domain only 1
chr7_+_27499315 Show fit	3.40	ENSMUST00000098644.2 ENSMUST00000108355.1	Prx Links Ensembl NCBI MGI UniProt Show fit	periaxin
chr3_-_69044697 Show fit	3.34	ENSMUST00000136512.1 ENSMUST00000143454.1 ENSMUST00000107802.1	Trim59 Links Ensembl NCBI MGI UniProt Show fit	tripartite motif-containing 59
chr15_+_102296256 Show fit	3.29	ENSMUST00000064924.4	Espl1 Links Ensembl NCBI MGI UniProt Show fit	extra spindle poles-like 1 (S. cerevisiae)
chr13_+_108316395 Show fit	3.21	ENSMUST00000171178.1	Depdc1b Links Ensembl NCBI MGI UniProt Show fit	DEP domain containing 1B
chr9_+_62858085 Show fit	3.20	ENSMUST00000034777.6 ENSMUST00000163820.1	Calml4 Links Ensembl NCBI MGI UniProt Show fit	calmodulin-like 4
chr2_+_35282380 Show fit	3.07	ENSMUST00000028239.6	Gsn Links Ensembl NCBI MGI UniProt Show fit	gelsolin
chrX_+_159303266 Show fit	3.03	ENSMUST00000112491.1	Rps6ka3 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S6 kinase polypeptide 3
chr2_+_118111876 Show fit	3.02	ENSMUST00000039559.8	Thbs1 Links Ensembl NCBI MGI UniProt Show fit	thrombospondin 1
chr7_+_28540863 Show fit	2.96	ENSMUST00000119180.2	Sycn Links Ensembl NCBI MGI UniProt Show fit	syncollin
chr15_+_99074968 Show fit	2.95	ENSMUST00000039665.6	Troap Links Ensembl NCBI MGI UniProt Show fit	trophinin associated protein
chr4_-_4138432 Show fit	2.90	ENSMUST00000070375.7	Penk Links Ensembl NCBI MGI UniProt Show fit	preproenkephalin
chr5_+_5573952 Show fit	2.86	ENSMUST00000101627.2	Gm8773 Links Ensembl NCBI MGI UniProt Show fit	predicted gene 8773
chr9_-_123678782 Show fit	2.86	ENSMUST00000170591.1 ENSMUST00000171647.1	Slc6a20a Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 6 (neurotransmitter transporter), member 20A
chrX_-_150812715 Show fit	2.85	ENSMUST00000112697.3	Maged2 Links Ensembl NCBI MGI UniProt Show fit	melanoma antigen, family D, 2
chr9_-_123678873 Show fit	2.75	ENSMUST00000040960.6	Slc6a20a Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 6 (neurotransmitter transporter), member 20A
chr7_+_5056856 Show fit	2.73	ENSMUST00000131368.1 ENSMUST00000123956.1	Ccdc106 Links Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 106
chr15_-_95528702 Show fit	2.64	ENSMUST00000166170.1	Nell2 Links Ensembl NCBI MGI UniProt Show fit	NEL-like 2
chr15_-_85581809 Show fit	2.63	ENSMUST00000023015.7	Wnt7b Links Ensembl NCBI MGI UniProt Show fit	wingless-related MMTV integration site 7B
chr1_-_75505641 Show fit	2.63	ENSMUST00000155084.1	Obsl1 Links Ensembl NCBI MGI UniProt Show fit	obscurin-like 1
chr17_+_56304313 Show fit	2.63	ENSMUST00000113035.1 ENSMUST00000113039.2 ENSMUST00000142387.1	Uhrf1 Links Ensembl NCBI MGI UniProt Show fit	ubiquitin-like, containing PHD and RING finger domains, 1
chr11_+_69095217 Show fit	2.50	ENSMUST00000101004.2	Per1 Links Ensembl NCBI MGI UniProt Show fit	period circadian clock 1
chr2_-_156839790 Show fit	2.48	ENSMUST00000134838.1 ENSMUST00000137463.1 ENSMUST00000149275.2	Gm14230 Links Ensembl NCBI MGI UniProt Show fit	predicted gene 14230
chr4_-_117178726 Show fit	2.48	ENSMUST00000153953.1 ENSMUST00000106436.1	Kif2c Links Ensembl NCBI MGI UniProt Show fit	kinesin family member 2C
chr11_-_83462961 Show fit	2.47	ENSMUST00000021020.6 ENSMUST00000119346.1 ENSMUST00000103209.3 ENSMUST00000108137.2	Mmp28 Links Ensembl NCBI MGI UniProt Show fit	matrix metallopeptidase 28 (epilysin)
chr4_+_44943727 Show fit	2.45	ENSMUST00000154177.1	Gm12678 Links Ensembl NCBI MGI UniProt Show fit	predicted gene 12678
chr5_-_24730635 Show fit	2.43	ENSMUST00000068693.5	Wdr86 Links Ensembl NCBI MGI UniProt Show fit	WD repeat domain 86
chr1_+_129273344 Show fit	2.41	ENSMUST00000073527.6 ENSMUST00000040311.7	Thsd7b Links Ensembl NCBI MGI UniProt Show fit	thrombospondin, type I, domain containing 7B
chr9_-_35558522 Show fit	2.36	ENSMUST00000034612.5	Ddx25 Links Ensembl NCBI MGI UniProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr4_+_43957401 Show fit	2.35	ENSMUST00000030202.7	Glipr2 Links Ensembl NCBI MGI UniProt Show fit	GLI pathogenesis-related 2
chr9_-_108190352 Show fit	2.33	ENSMUST00000035208.7	Bsn Links Ensembl NCBI MGI UniProt Show fit	bassoon
chr7_-_126704816 Show fit	2.31	ENSMUST00000032949.7	Coro1a Links Ensembl NCBI MGI UniProt Show fit	coronin, actin binding protein 1A
chr2_-_91931675 Show fit	2.30	ENSMUST00000111309.1	Mdk Links Ensembl NCBI MGI UniProt Show fit	midkine
chr8_+_123411424 Show fit	2.26	ENSMUST00000071134.3	Tubb3 Links Ensembl NCBI MGI UniProt Show fit	tubulin, beta 3 class III
chr1_-_75506331 Show fit	2.23	ENSMUST00000113567.2 ENSMUST00000113565.2	Obsl1 Links Ensembl NCBI MGI UniProt Show fit	obscurin-like 1
chr7_-_44227421 Show fit	2.20	ENSMUST00000072123.4	Gm10109 Links Ensembl NCBI MGI UniProt Show fit	predicted gene 10109
chr2_-_92371039 Show fit	2.19	ENSMUST00000068586.6	Gyltl1b Links Ensembl NCBI MGI UniProt Show fit	glycosyltransferase-like 1B
chr10_+_79777261 Show fit	2.18	ENSMUST00000020575.4	Fstl3 Links Ensembl NCBI MGI UniProt Show fit	follistatin-like 3
chr11_+_75656103 Show fit	2.16	ENSMUST00000136935.1	Myo1c Links Ensembl NCBI MGI UniProt Show fit	myosin IC
chr11_+_96282648 Show fit	2.16	ENSMUST00000168043.1	Hoxb8 Links Ensembl NCBI MGI UniProt Show fit	homeobox B8
chr8_-_105637403 Show fit	2.16	ENSMUST00000182046.1	Gm5914 Links Ensembl NCBI MGI UniProt Show fit	predicted gene 5914
chr12_+_103388656 Show fit	2.15	ENSMUST00000101094.2 ENSMUST00000021620.6	Otub2 Links Ensembl NCBI MGI UniProt Show fit	OTU domain, ubiquitin aldehyde binding 2
chr13_-_99516537 Show fit	2.15	ENSMUST00000064762.4	Map1b Links Ensembl NCBI MGI UniProt Show fit	microtubule-associated protein 1B
chr3_+_31149934 Show fit	2.13	ENSMUST00000046174.6	Cldn11 Links Ensembl NCBI MGI UniProt Show fit	claudin 11
chrX_+_74329058 Show fit	2.12	ENSMUST00000004326.3	Plxna3 Links Ensembl NCBI MGI UniProt Show fit	plexin A3
chr11_-_78245942 Show fit	2.08	ENSMUST00000002121.4	Supt6 Links Ensembl NCBI MGI UniProt Show fit	suppressor of Ty 6
chr7_-_126704736 Show fit	2.06	ENSMUST00000131415.1	Coro1a Links Ensembl NCBI MGI UniProt Show fit	coronin, actin binding protein 1A
chr17_-_25727364 Show fit	2.01	ENSMUST00000170070.1 ENSMUST00000048054.7	Chtf18 Links Ensembl NCBI MGI UniProt Show fit	CTF18, chromosome transmission fidelity factor 18
chr7_+_27258725 Show fit	2.01	ENSMUST00000079258.6	Numbl Links Ensembl NCBI MGI UniProt Show fit	numb-like
chr12_-_32953772 Show fit	1.99	ENSMUST00000180391.1 ENSMUST00000181670.1	4933406C10Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 4933406C10 gene
chr11_+_70000578 Show fit	1.95	ENSMUST00000019362.8	Dvl2 Links Ensembl NCBI MGI UniProt Show fit	dishevelled 2, dsh homolog (Drosophila)
chr11_+_100415722 Show fit	1.94	ENSMUST00000107400.2	Fkbp10 Links Ensembl NCBI MGI UniProt Show fit	FK506 binding protein 10
chrX_-_150812932 Show fit	1.93	ENSMUST00000131241.1 ENSMUST00000147152.1 ENSMUST00000143843.1	Maged2 Links Ensembl NCBI MGI UniProt Show fit	melanoma antigen, family D, 2
chr7_-_118443549 Show fit	1.91	ENSMUST00000081574.4	Syt17 Links Ensembl NCBI MGI UniProt Show fit	synaptotagmin XVII
chr5_-_117319242 Show fit	1.91	ENSMUST00000100834.1	Gm10399 Links Ensembl NCBI MGI UniProt Show fit	predicted gene 10399
chr7_+_5056706 Show fit	1.90	ENSMUST00000144802.1	Ccdc106 Links Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 106
chr2_+_29889720 Show fit	1.85	ENSMUST00000113767.1	Odf2 Links Ensembl NCBI MGI UniProt Show fit	outer dense fiber of sperm tails 2
chr18_-_21652362 Show fit	1.82	ENSMUST00000049105.4	Klhl14 Links Ensembl NCBI MGI UniProt Show fit	kelch-like 14
chr6_-_125494754 Show fit	1.80	ENSMUST00000032492.8	Cd9 Links Ensembl NCBI MGI UniProt Show fit	CD9 antigen
chr15_+_78899755 Show fit	1.80	ENSMUST00000001226.3 ENSMUST00000061239.7 ENSMUST00000109698.2	Sh3bp1 Links Ensembl NCBI MGI UniProt Show fit	SH3-domain binding protein 1
chr8_+_68880491 Show fit	1.79	ENSMUST00000015712.8	Lpl Links Ensembl NCBI MGI UniProt Show fit	lipoprotein lipase
chr11_+_115154139 Show fit	1.79	ENSMUST00000021076.5	Rab37 Links Ensembl NCBI MGI UniProt Show fit	RAB37, member of RAS oncogene family
chr15_-_95528228 Show fit	1.78	ENSMUST00000075275.2	Nell2 Links Ensembl NCBI MGI UniProt Show fit	NEL-like 2
chr6_-_118780324 Show fit	1.76	ENSMUST00000112793.3 ENSMUST00000075591.6 ENSMUST00000078320.7 ENSMUST00000112790.2	Cacna1c Links Ensembl NCBI MGI UniProt Show fit	calcium channel, voltage-dependent, L type, alpha 1C subunit
chr4_+_43957678 Show fit	1.76	ENSMUST00000107855.1	Glipr2 Links Ensembl NCBI MGI UniProt Show fit	GLI pathogenesis-related 2
chr8_+_70501116 Show fit	1.76	ENSMUST00000127983.1	Crlf1 Links Ensembl NCBI MGI UniProt Show fit	cytokine receptor-like factor 1
chr3_+_105904377 Show fit	1.71	ENSMUST00000000574.1	Adora3 Links Ensembl NCBI MGI UniProt Show fit	adenosine A3 receptor
chr2_+_29890096 Show fit	1.71	ENSMUST00000113762.1 ENSMUST00000113765.1	Odf2 Links Ensembl NCBI MGI UniProt Show fit	outer dense fiber of sperm tails 2
chr1_+_65311257 Show fit	1.70	ENSMUST00000027083.6	Pth2r Links Ensembl NCBI MGI UniProt Show fit	parathyroid hormone 2 receptor
chr4_+_154869585 Show fit	1.68	ENSMUST00000079269.7 ENSMUST00000163732.1 ENSMUST00000080559.6	Mmel1 Links Ensembl NCBI MGI UniProt Show fit	membrane metallo-endopeptidase-like 1
chr7_+_99535439 Show fit	1.65	ENSMUST00000098266.2 ENSMUST00000179755.1	Arrb1 Links Ensembl NCBI MGI UniProt Show fit	arrestin, beta 1
chr2_+_29889785 Show fit	1.64	ENSMUST00000113763.1 ENSMUST00000113757.1 ENSMUST00000113756.1 ENSMUST00000133233.1 ENSMUST00000113759.2 ENSMUST00000113755.1 ENSMUST00000137558.1 ENSMUST00000046571.7	Odf2 Links Ensembl NCBI MGI UniProt Show fit	outer dense fiber of sperm tails 2
chr11_-_45955465 Show fit	1.64	ENSMUST00000011398.6	Thg1l Links Ensembl NCBI MGI UniProt Show fit	tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr10_+_80016653 Show fit	1.63	ENSMUST00000099501.3	Hmha1 Links Ensembl NCBI MGI UniProt Show fit	histocompatibility (minor) HA-1
chr3_-_92485886 Show fit	1.63	ENSMUST00000054599.7	Sprr1a Links Ensembl NCBI MGI UniProt Show fit	small proline-rich protein 1A
chr8_-_105637350 Show fit	1.61	ENSMUST00000182863.1	Gm5914 Links Ensembl NCBI MGI UniProt Show fit	predicted gene 5914
chr11_+_96282529 Show fit	1.59	ENSMUST00000125410.1	Hoxb8 Links Ensembl NCBI MGI UniProt Show fit	homeobox B8
chr13_+_44729794 Show fit	1.58	ENSMUST00000172830.1	Jarid2 Links Ensembl NCBI MGI UniProt Show fit	jumonji, AT rich interactive domain 2
chr10_+_80016901 Show fit	1.57	ENSMUST00000105373.1	Hmha1 Links Ensembl NCBI MGI UniProt Show fit	histocompatibility (minor) HA-1
chr9_-_54661870 Show fit	1.57	ENSMUST00000034822.5	Acsbg1 Links Ensembl NCBI MGI UniProt Show fit	acyl-CoA synthetase bubblegum family member 1
chr11_-_34833631 Show fit	1.56	ENSMUST00000093191.2	Spdl1 Links Ensembl NCBI MGI UniProt Show fit	spindle apparatus coiled-coil protein 1
chr7_+_125603420 Show fit	1.54	ENSMUST00000033000.6	Il21r Links Ensembl NCBI MGI UniProt Show fit	interleukin 21 receptor
chr14_-_54926784 Show fit	1.54	ENSMUST00000022813.6	Efs Links Ensembl NCBI MGI UniProt Show fit	embryonal Fyn-associated substrate
chr2_+_156840077 Show fit	1.53	ENSMUST00000081335.6 ENSMUST00000073352.3	Tgif2 Links Ensembl NCBI MGI UniProt Show fit	TGFB-induced factor homeobox 2
chr1_+_167001457 Show fit	1.53	ENSMUST00000126198.1	Fam78b Links Ensembl NCBI MGI UniProt Show fit	family with sequence similarity 78, member B
chr13_-_49320219 Show fit	1.52	ENSMUST00000110086.1	Fgd3 Links Ensembl NCBI MGI UniProt Show fit	FYVE, RhoGEF and PH domain containing 3
chr15_-_100669535 Show fit	1.49	ENSMUST00000183211.1	Bin2 Links Ensembl NCBI MGI UniProt Show fit	bridging integrator 2
chr2_+_29890534 Show fit	1.48	ENSMUST00000113764.3	Odf2 Links Ensembl NCBI MGI UniProt Show fit	outer dense fiber of sperm tails 2
chr11_+_87760533 Show fit	1.46	ENSMUST00000039627.5 ENSMUST00000100644.3	Bzrap1 Links Ensembl NCBI MGI UniProt Show fit	benzodiazepine receptor associated protein 1
chr4_-_136956784 Show fit	1.45	ENSMUST00000030420.8	Epha8 Links Ensembl NCBI MGI UniProt Show fit	Eph receptor A8
chr2_+_29890063 Show fit	1.44	ENSMUST00000028128.6	Odf2 Links Ensembl NCBI MGI UniProt Show fit	outer dense fiber of sperm tails 2
chr7_-_25297866 Show fit	1.42	ENSMUST00000148150.1 ENSMUST00000155118.1	Pafah1b3 Links Ensembl NCBI MGI UniProt Show fit	platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr8_+_120002720 Show fit	1.41	ENSMUST00000108972.3	Crispld2 Links Ensembl NCBI MGI UniProt Show fit	cysteine-rich secretory protein LCCL domain containing 2
chr11_-_61494173 Show fit	1.40	ENSMUST00000101085.2 ENSMUST00000079080.6 ENSMUST00000108714.1	Mapk7 Links Ensembl NCBI MGI UniProt Show fit	mitogen-activated protein kinase 7
chr12_-_4233958 Show fit	1.40	ENSMUST00000111169.3 ENSMUST00000020981.5	Cenpo Links Ensembl NCBI MGI UniProt Show fit	centromere protein O
chr14_-_33185066 Show fit	1.37	ENSMUST00000061753.8 ENSMUST00000130509.2	Wdfy4 Links Ensembl NCBI MGI UniProt Show fit	WD repeat and FYVE domain containing 4
chr5_+_43818893 Show fit	1.36	ENSMUST00000101237.4	Bst1 Links Ensembl NCBI MGI UniProt Show fit	bone marrow stromal cell antigen 1
chr11_-_76399107 Show fit	1.36	ENSMUST00000021204.3	Nxn Links Ensembl NCBI MGI UniProt Show fit	nucleoredoxin
chr2_+_105127200 Show fit	1.36	ENSMUST00000139585.1	Wt1 Links Ensembl NCBI MGI UniProt Show fit	Wilms tumor 1 homolog
chr17_+_34039437 Show fit	1.33	ENSMUST00000131134.1 ENSMUST00000087497.4 ENSMUST00000114255.1 ENSMUST00000114252.1	Col11a2 Links Ensembl NCBI MGI UniProt Show fit	collagen, type XI, alpha 2
chrX_+_159697308 Show fit	1.32	ENSMUST00000123433.1	Sh3kbp1 Links Ensembl NCBI MGI UniProt Show fit	SH3-domain kinase binding protein 1
chr13_+_6548154 Show fit	1.32	ENSMUST00000021611.8	Pitrm1 Links Ensembl NCBI MGI UniProt Show fit	pitrilysin metallepetidase 1
chr18_+_62180119 Show fit	1.31	ENSMUST00000067743.1	Gm9949 Links Ensembl NCBI MGI UniProt Show fit	predicted gene 9949
chr7_+_80186835 Show fit	1.30	ENSMUST00000107383.1 ENSMUST00000032754.7	Sema4b Links Ensembl NCBI MGI UniProt Show fit	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr5_-_115300912 Show fit	1.30	ENSMUST00000112090.1	Dynll1 Links Ensembl NCBI MGI UniProt Show fit	dynein light chain LC8-type 1
chr14_+_84443553 Show fit	1.30	ENSMUST00000071370.5	Pcdh17 Links Ensembl NCBI MGI UniProt Show fit	protocadherin 17
chr17_-_15041457 Show fit	1.29	ENSMUST00000097400.4 ENSMUST00000097398.4 ENSMUST00000040746.6	Gm3448 Links Ensembl NCBI MGI UniProt Show fit Tcte3 Links Ensembl NCBI MGI UniProt Show fit	predicted gene 3448 t-complex-associated testis expressed 3
chr5_-_5266038 Show fit	1.28	ENSMUST00000115451.1 ENSMUST00000115452.1 ENSMUST00000131392.1	Cdk14 Links Ensembl NCBI MGI UniProt Show fit	cyclin-dependent kinase 14
chr11_+_53519725 Show fit	1.28	ENSMUST00000108987.1 ENSMUST00000121334.1 ENSMUST00000117061.1	Sept8 Links Ensembl NCBI MGI UniProt Show fit	septin 8
chr5_-_115300957 Show fit	1.28	ENSMUST00000009157.3	Dynll1 Links Ensembl NCBI MGI UniProt Show fit	dynein light chain LC8-type 1
chr1_+_72824482 Show fit	1.27	ENSMUST00000047328.4	Igfbp2 Links Ensembl NCBI MGI UniProt Show fit	insulin-like growth factor binding protein 2
chr1_-_133906973 Show fit	1.26	ENSMUST00000126123.1	Optc Links Ensembl NCBI MGI UniProt Show fit	opticin
chr7_+_25267669 Show fit	1.23	ENSMUST00000169266.1	Cic Links Ensembl NCBI MGI UniProt Show fit	capicua homolog (Drosophila)
chr6_+_125067913 Show fit	1.22	ENSMUST00000088292.5	Lpar5 Links Ensembl NCBI MGI UniProt Show fit	lysophosphatidic acid receptor 5
chr2_-_153444441 Show fit	1.22	ENSMUST00000109784.1	8430427H17Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 8430427H17 gene
chr13_+_44730726 Show fit	1.22	ENSMUST00000173704.1 ENSMUST00000044608.7 ENSMUST00000173367.1	Jarid2 Links Ensembl NCBI MGI UniProt Show fit	jumonji, AT rich interactive domain 2
chr11_+_77982710 Show fit	1.22	ENSMUST00000108360.1 ENSMUST00000049167.7	Phf12 Links Ensembl NCBI MGI UniProt Show fit	PHD finger protein 12
chr3_+_92288566 Show fit	1.22	ENSMUST00000090872.4	Sprr2a3 Links Ensembl NCBI MGI UniProt Show fit	small proline-rich protein 2A3
chr6_+_29694204 Show fit	1.21	ENSMUST00000046750.7 ENSMUST00000115250.3	Tspan33 Links Ensembl NCBI MGI UniProt Show fit	tetraspanin 33
chr2_-_113848655 Show fit	1.21	ENSMUST00000102545.1 ENSMUST00000110948.1	Arhgap11a Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 11A
chr17_-_44735612 Show fit	1.20	ENSMUST00000162373.1 ENSMUST00000162878.1	Runx2 Links Ensembl NCBI MGI UniProt Show fit	runt related transcription factor 2
chr9_-_44234014 Show fit	1.20	ENSMUST00000037644.6	Cbl Links Ensembl NCBI MGI UniProt Show fit	Casitas B-lineage lymphoma
chrX_+_140956892 Show fit	1.20	ENSMUST00000112971.1	Atg4a Links Ensembl NCBI MGI UniProt Show fit	autophagy related 4A, cysteine peptidase
chrX_-_94542037 Show fit	1.19	ENSMUST00000026142.7	Maged1 Links Ensembl NCBI MGI UniProt Show fit	melanoma antigen, family D, 1
chr15_-_56694525 Show fit	1.17	ENSMUST00000050544.7	Has2 Links Ensembl NCBI MGI UniProt Show fit	hyaluronan synthase 2
chr11_-_106349389 Show fit	1.15	ENSMUST00000021056.7	Scn4a Links Ensembl NCBI MGI UniProt Show fit	sodium channel, voltage-gated, type IV, alpha
chr2_+_174643534 Show fit	1.14	ENSMUST00000059452.5	Zfp831 Links Ensembl NCBI MGI UniProt Show fit	zinc finger protein 831
chr7_-_25297967 Show fit	1.13	ENSMUST00000005583.5	Pafah1b3 Links Ensembl NCBI MGI UniProt Show fit	platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr11_+_115462464 Show fit	1.12	ENSMUST00000106532.3 ENSMUST00000092445.5 ENSMUST00000153466.1	Slc16a5 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 16 (monocarboxylic acid transporters), member 5
chr1_+_43445736 Show fit	1.11	ENSMUST00000086421.5 ENSMUST00000114744.1	Nck2 Links Ensembl NCBI MGI UniProt Show fit	non-catalytic region of tyrosine kinase adaptor protein 2
chr8_-_22125030 Show fit	1.11	ENSMUST00000169834.1	Nek5 Links Ensembl NCBI MGI UniProt Show fit	NIMA (never in mitosis gene a)-related expressed kinase 5
chr2_-_113848601 Show fit	1.10	ENSMUST00000110949.2	Arhgap11a Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 11A
chr13_-_23551648 Show fit	1.10	ENSMUST00000102971.1	Hist1h4f Links Ensembl NCBI MGI UniProt Show fit	histone cluster 1, H4f
chrX_-_53114530 Show fit	1.10	ENSMUST00000114843.2	Plac1 Links Ensembl NCBI MGI UniProt Show fit	placental specific protein 1
chr18_-_62179948 Show fit	1.10	ENSMUST00000053640.3	Adrb2 Links Ensembl NCBI MGI UniProt Show fit	adrenergic receptor, beta 2
chr7_+_130865835 Show fit	1.10	ENSMUST00000075181.4 ENSMUST00000048180.5	Plekha1 Links Ensembl NCBI MGI UniProt Show fit	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr9_-_50752348 Show fit	1.09	ENSMUST00000042790.3	Hspb2 Links Ensembl NCBI MGI UniProt Show fit	heat shock protein 2
chr8_+_121127827 Show fit	1.08	ENSMUST00000181609.1	Foxl1 Links Ensembl NCBI MGI UniProt Show fit	forkhead box L1
chr6_-_28830345 Show fit	1.08	ENSMUST00000171353.1	Lrrc4 Links Ensembl NCBI MGI UniProt Show fit	leucine rich repeat containing 4
chr2_+_106693185 Show fit	1.07	ENSMUST00000111063.1	Mpped2 Links Ensembl NCBI MGI UniProt Show fit	metallophosphoesterase domain containing 2
chr7_+_128129536 Show fit	1.07	ENSMUST00000033053.6	Itgax Links Ensembl NCBI MGI UniProt Show fit	integrin alpha X
chr11_-_70229677 Show fit	1.07	ENSMUST00000153449.1 ENSMUST00000000326.5	Bcl6b Links Ensembl NCBI MGI UniProt Show fit	B cell CLL/lymphoma 6, member B
chr6_-_101377342 Show fit	1.07	ENSMUST00000151175.1	Pdzrn3 Links Ensembl NCBI MGI UniProt Show fit	PDZ domain containing RING finger 3
chr15_+_40655020 Show fit	1.06	ENSMUST00000053467.4	Zfpm2 Links Ensembl NCBI MGI UniProt Show fit	zinc finger protein, multitype 2
chr6_-_148944750 Show fit	1.05	ENSMUST00000111562.1 ENSMUST00000081956.5	Fam60a Links Ensembl NCBI MGI UniProt Show fit	family with sequence similarity 60, member A
chr11_+_73018986 Show fit	1.05	ENSMUST00000092937.6	Camkk1 Links Ensembl NCBI MGI UniProt Show fit	calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr5_-_38561658 Show fit	1.04	ENSMUST00000005234.9	Wdr1 Links Ensembl NCBI MGI UniProt Show fit	WD repeat domain 1
chr5_+_117319292 Show fit	1.03	ENSMUST00000086464.4	Vsig10 Links Ensembl NCBI MGI UniProt Show fit	V-set and immunoglobulin domain containing 10
chr8_+_83608175 Show fit	1.03	ENSMUST00000005620.8	Dnajb1 Links Ensembl NCBI MGI UniProt Show fit	DnaJ (Hsp40) homolog, subfamily B, member 1
chr8_+_23139157 Show fit	1.01	ENSMUST00000174435.1	Ank1 Links Ensembl NCBI MGI UniProt Show fit	ankyrin 1, erythroid
chr17_+_34894515 Show fit	1.00	ENSMUST00000052778.8	Zbtb12 Links Ensembl NCBI MGI UniProt Show fit	zinc finger and BTB domain containing 12
chr6_-_52218686 Show fit	1.00	ENSMUST00000134367.2	Hoxa7 Links Ensembl NCBI MGI UniProt Show fit	homeobox A7
chr3_-_116253467 Show fit	1.00	ENSMUST00000090473.5	Gpr88 Links Ensembl NCBI MGI UniProt Show fit	G-protein coupled receptor 88
chr4_+_123233556 Show fit	1.00	ENSMUST00000040821.4	Heyl Links Ensembl NCBI MGI UniProt Show fit	hairy/enhancer-of-split related with YRPW motif-like
chr11_+_49901803 Show fit	0.99	ENSMUST00000093141.5 ENSMUST00000093142.5	Rasgef1c Links Ensembl NCBI MGI UniProt Show fit	RasGEF domain family, member 1C
chr18_+_52767994 Show fit	0.99	ENSMUST00000025413.7 ENSMUST00000163742.2 ENSMUST00000178011.1	Sncaip Links Ensembl NCBI MGI UniProt Show fit	synuclein, alpha interacting protein (synphilin)
chr19_+_8802486 Show fit	0.99	ENSMUST00000172175.1	Zbtb3 Links Ensembl NCBI MGI UniProt Show fit	zinc finger and BTB domain containing 3
chr2_-_59948155 Show fit	0.97	ENSMUST00000153136.1	Baz2b Links Ensembl NCBI MGI UniProt Show fit	bromodomain adjacent to zinc finger domain, 2B
chr7_+_128246953 Show fit	0.96	ENSMUST00000167965.1	Tgfb1i1 Links Ensembl NCBI MGI UniProt Show fit	transforming growth factor beta 1 induced transcript 1
chr12_+_32378692 Show fit	0.96	ENSMUST00000172332.2	Ccdc71l Links Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 71 like
chr19_+_6384395 Show fit	0.96	ENSMUST00000035269.8 ENSMUST00000113483.1	Pygm Links Ensembl NCBI MGI UniProt Show fit	muscle glycogen phosphorylase
chr2_-_33431324 Show fit	0.96	ENSMUST00000113158.1	Zbtb34 Links Ensembl NCBI MGI UniProt Show fit	zinc finger and BTB domain containing 34
chr6_-_41636389 Show fit	0.96	ENSMUST00000031902.5	Trpv6 Links Ensembl NCBI MGI UniProt Show fit	transient receptor potential cation channel, subfamily V, member 6
chr14_+_25607797 Show fit	0.96	ENSMUST00000160229.1	Zmiz1 Links Ensembl NCBI MGI UniProt Show fit	zinc finger, MIZ-type containing 1

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Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.6	21.0	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
2.4	7.1	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
2.2	11.2	GO:0002554	serotonin secretion by platelet(GO:0002554)
1.9	5.8	GO:0071918	urea transmembrane transport(GO:0071918)
1.7	5.0	GO:0045660	positive regulation of neutrophil differentiation(GO:0045660)
1.4	5.6	GO:0035524	proline transmembrane transport(GO:0035524)
1.1	3.4	GO:0030221	basophil differentiation(GO:0030221)
1.1	4.4	GO:0060032	notochord regression(GO:0060032)
1.0	3.1	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of establishment of T cell polarity(GO:1903903)
1.0	5.9	GO:0030913	paranodal junction assembly(GO:0030913)
1.0	9.5	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.9	11.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.9	3.4	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.8	0.8	GO:0060915	fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.8	2.3	GO:0099526	presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.7	4.4	GO:0032796	uropod organization(GO:0032796)
0.7	2.0	GO:0021849	neuroblast division in subventricular zone(GO:0021849)
0.7	2.6	GO:0072054	establishment or maintenance of polarity of embryonic epithelium(GO:0016332) renal outer medulla development(GO:0072054) inner medullary collecting duct development(GO:0072061)
0.6	1.9	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.6	9.2	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.6	4.2	GO:2000465	regulation of glycogen (starch) synthase activity(GO:2000465)
0.6	4.8	GO:0070294	renal sodium ion absorption(GO:0070294)
0.6	3.5	GO:0051790	acetate metabolic process(GO:0006083) short-chain fatty acid biosynthetic process(GO:0051790)
0.5	3.1	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.5	13.5	GO:0045780	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.5	2.5	GO:0097167	circadian regulation of translation(GO:0097167)
0.5	2.5	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.5	2.5	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.5	2.9	GO:2000987	positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.5	8.4	GO:0070307	lens fiber cell development(GO:0070307)
0.5	14.1	GO:0008340	determination of adult lifespan(GO:0008340)
0.5	1.4	GO:0070375	ERK5 cascade(GO:0070375)
0.5	1.4	GO:2001076	negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.4	1.3	GO:1904978	regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.4	2.1	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.4	1.2	GO:0045226	extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.4	3.0	GO:1904378	maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.4	1.8	GO:0055096	lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.4	2.1	GO:0021636	trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.4	1.8	GO:0098912	membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.3	9.1	GO:0015701	bicarbonate transport(GO:0015701)
0.3	7.6	GO:0021516	dorsal spinal cord development(GO:0021516)
0.3	2.3	GO:0030421	defecation(GO:0030421)
0.3	0.3	GO:1904907	negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.3	4.9	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.3	2.8	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.3	0.9	GO:1902283	negative regulation of primary amine oxidase activity(GO:1902283)
0.3	0.9	GO:2000312	regulation of kainate selective glutamate receptor activity(GO:2000312)
0.3	8.7	GO:0097320	membrane tubulation(GO:0097320)
0.3	1.1	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.3	4.4	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.3	1.7	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.3	1.1	GO:1904504	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.3	1.9	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.3	1.1	GO:0007525	somatic muscle development(GO:0007525)
0.3	1.1	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.3	1.1	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.3	11.4	GO:0048821	erythrocyte development(GO:0048821)
0.3	1.0	GO:0030043	actin filament fragmentation(GO:0030043)
0.2	1.0	GO:0061743	motor learning(GO:0061743)
0.2	1.0	GO:0072014	proximal tubule development(GO:0072014)
0.2	1.2	GO:0051697	protein delipidation(GO:0051697)
0.2	2.1	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.2	2.6	GO:2000576	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2	0.9	GO:1904425	negative regulation of GTP binding(GO:1904425)
0.2	1.3	GO:0060023	soft palate development(GO:0060023)
0.2	3.3	GO:0000212	meiotic spindle organization(GO:0000212)
0.2	0.7	GO:0071288	cellular response to mercury ion(GO:0071288) cellular response to water stimulus(GO:0071462)
0.2	1.3	GO:1902748	positive regulation of lens fiber cell differentiation(GO:1902748)
0.2	4.3	GO:0007614	short-term memory(GO:0007614)
0.2	0.6	GO:0046061	dATP catabolic process(GO:0046061)
0.2	0.2	GO:0031335	regulation of sulfur amino acid metabolic process(GO:0031335)
0.2	1.1	GO:0090214	spongiotrophoblast layer developmental growth(GO:0090214)
0.2	0.5	GO:0036292	DNA rewinding(GO:0036292)
0.2	2.9	GO:0090308	regulation of methylation-dependent chromatin silencing(GO:0090308)
0.2	1.7	GO:0002349	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.2	0.8	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.2	0.3	GO:0032765	positive regulation of mast cell cytokine production(GO:0032765)
0.2	1.1	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.2	2.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.2	0.8	GO:0036006	response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.2	0.8	GO:0021993	initiation of neural tube closure(GO:0021993)
0.2	0.3	GO:1901994	negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.2	7.8	GO:0010883	regulation of lipid storage(GO:0010883)
0.2	2.7	GO:0070831	basement membrane assembly(GO:0070831)
0.2	3.5	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.1	0.4	GO:0019046	release from viral latency(GO:0019046)
0.1	1.3	GO:0071231	neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1	1.5	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1	3.3	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.1	1.1	GO:0015871	choline transport(GO:0015871)
0.1	0.6	GO:0008272	sulfate transport(GO:0008272)
0.1	2.6	GO:0001553	luteinization(GO:0001553)
0.1	1.0	GO:0007296	vitellogenesis(GO:0007296)
0.1	0.9	GO:0045196	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1	0.5	GO:0010726	positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1	2.1	GO:0061162	establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1	0.8	GO:0006543	glutamine catabolic process(GO:0006543)
0.1	3.4	GO:0048268	clathrin coat assembly(GO:0048268)
0.1	1.6	GO:0034501	protein localization to kinetochore(GO:0034501)
0.1	0.5	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636)
0.1	0.1	GO:0007521	muscle cell fate determination(GO:0007521)
0.1	1.2	GO:0002051	osteoblast fate commitment(GO:0002051)
0.1	0.2	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.1	1.1	GO:0045656	negative regulation of monocyte differentiation(GO:0045656)
0.1	1.8	GO:0099612	protein localization to axon(GO:0099612)
0.1	8.3	GO:1902017	regulation of cilium assembly(GO:1902017)
0.1	0.7	GO:0060623	regulation of chromosome condensation(GO:0060623)
0.1	0.4	GO:0009436	glyoxylate catabolic process(GO:0009436)
0.1	0.7	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.1	1.0	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.1	0.7	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
0.1	0.3	GO:0001983	baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.1	1.2	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1	0.2	GO:0046077	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1	1.5	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1	0.2	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.1	0.5	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.1	1.0	GO:0098703	calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1	1.9	GO:1903861	positive regulation of dendrite extension(GO:1903861)
0.1	1.1	GO:0097119	postsynaptic density protein 95 clustering(GO:0097119)
0.1	1.4	GO:0034389	lipid particle organization(GO:0034389)
0.1	0.2	GO:0072236	metanephric loop of Henle development(GO:0072236)
0.1	0.3	GO:0010841	regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.1	1.9	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.1	0.4	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	0.3	GO:0009957	epidermal cell fate specification(GO:0009957)
0.1	0.5	GO:0051013	microtubule severing(GO:0051013)
0.1	0.3	GO:1905150	regulation of voltage-gated sodium channel activity(GO:1905150)
0.1	3.0	GO:0010718	positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1	2.1	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.1	1.7	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1	1.1	GO:0038092	nodal signaling pathway(GO:0038092)
0.1	0.8	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1	0.4	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1	2.8	GO:0018149	peptide cross-linking(GO:0018149)
0.1	0.2	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.1	0.1	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.1	0.3	GO:0032811	negative regulation of epinephrine secretion(GO:0032811)
0.1	1.3	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.1	0.8	GO:0046069	cGMP catabolic process(GO:0046069)
0.1	3.8	GO:0032418	lysosome localization(GO:0032418)
0.1	1.1	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.1	0.2	GO:0032241	positive regulation of nucleobase-containing compound transport(GO:0032241)
0.1	1.2	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1	0.3	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.5	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.1	0.7	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.1	0.4	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	4.2	GO:0032024	positive regulation of insulin secretion(GO:0032024)
0.0	0.4	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.3	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.3	GO:1900378	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0	0.5	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0	0.3	GO:0006108	malate metabolic process(GO:0006108)
0.0	1.4	GO:0090022	regulation of neutrophil chemotaxis(GO:0090022)
0.0	1.2	GO:0048266	behavioral response to pain(GO:0048266)
0.0	0.2	GO:2001025	positive regulation of response to drug(GO:2001025)
0.0	1.0	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.4	GO:1900034	regulation of cellular response to heat(GO:1900034)
0.0	1.4	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.7	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	2.3	GO:0071427	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0	0.4	GO:0060347	heart trabecula formation(GO:0060347)
0.0	0.9	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.4	GO:0097623	potassium ion export across plasma membrane(GO:0097623)
0.0	1.5	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	1.1	GO:0050798	activated T cell proliferation(GO:0050798)
0.0	0.1	GO:1905034	regulation of defense response to fungus(GO:1900150) regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035)
0.0	0.6	GO:0090382	phagosome maturation(GO:0090382)
0.0	3.2	GO:0030177	positive regulation of Wnt signaling pathway(GO:0030177)
0.0	0.5	GO:0035428	hexose transmembrane transport(GO:0035428)
0.0	2.4	GO:0002224	toll-like receptor signaling pathway(GO:0002224)
0.0	0.1	GO:0097240	telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	0.6	GO:0034508	centromere complex assembly(GO:0034508)
0.0	1.2	GO:0048286	lung alveolus development(GO:0048286)
0.0	1.0	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.6	GO:0060065	uterus development(GO:0060065)
0.0	0.3	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.3	GO:0051601	exocyst localization(GO:0051601)
0.0	0.2	GO:1900121	negative regulation of receptor binding(GO:1900121)
0.0	0.8	GO:0050919	negative chemotaxis(GO:0050919)
0.0	0.8	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.5	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.1	GO:1902606	regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	1.0	GO:0051591	response to cAMP(GO:0051591)
0.0	0.3	GO:0045109	intermediate filament organization(GO:0045109)
0.0	0.5	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.7	GO:0031397	negative regulation of protein ubiquitination(GO:0031397)
0.0	0.5	GO:0036465	synaptic vesicle recycling(GO:0036465)
0.0	0.5	GO:1901381	positive regulation of potassium ion transmembrane transport(GO:1901381)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.7	11.2	GO:0030312	external encapsulating structure(GO:0030312)
1.2	3.6	GO:0034774	secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.8	2.3	GO:1990257	piccolo-bassoon transport vesicle(GO:1990257)
0.8	3.1	GO:0045160	myosin I complex(GO:0045160)
0.7	2.9	GO:0032280	symmetric synapse(GO:0032280)
0.5	8.1	GO:0097539	ciliary transition fiber(GO:0097539)
0.5	12.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.5	1.8	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.4	12.9	GO:0001891	phagocytic cup(GO:0001891)
0.4	0.9	GO:0043259	laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.4	3.0	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.3	3.0	GO:0005577	fibrinogen complex(GO:0005577)
0.3	9.2	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.3	4.4	GO:0097542	ciliary tip(GO:0097542)
0.3	4.7	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.3	0.9	GO:0005607	laminin-2 complex(GO:0005607)
0.3	2.3	GO:0030478	actin cap(GO:0030478)
0.3	1.0	GO:0099522	region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.3	1.3	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2	4.0	GO:0033270	paranode region of axon(GO:0033270)
0.2	2.0	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.2	1.1	GO:1990769	proximal neuron projection(GO:1990769)
0.2	2.6	GO:1904115	axon cytoplasm(GO:1904115)
0.2	4.9	GO:0005859	muscle myosin complex(GO:0005859)
0.2	1.4	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	3.3	GO:0030992	intraciliary transport particle B(GO:0030992)
0.1	0.9	GO:0005726	perichromatin fibrils(GO:0005726)
0.1	2.4	GO:0033391	chromatoid body(GO:0033391)
0.1	4.0	GO:0097228	sperm principal piece(GO:0097228)
0.1	0.7	GO:0031310	integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1	1.6	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.1	1.2	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.1	1.2	GO:0016600	flotillin complex(GO:0016600)
0.1	9.9	GO:0014704	intercalated disc(GO:0014704)
0.1	0.8	GO:0001652	granular component(GO:0001652)
0.1	2.1	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.1	1.7	GO:0031143	pseudopodium(GO:0031143)
0.1	2.1	GO:0043196	varicosity(GO:0043196)
0.1	0.9	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.1	1.1	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.1	1.6	GO:0016580	Sin3 complex(GO:0016580)
0.1	2.8	GO:0001533	cornified envelope(GO:0001533)
0.1	2.5	GO:0035371	microtubule plus-end(GO:0035371)
0.1	0.3	GO:0032585	multivesicular body membrane(GO:0032585)
0.1	3.8	GO:0016235	aggresome(GO:0016235)
0.1	1.0	GO:0036038	MKS complex(GO:0036038)
0.1	5.9	GO:0005882	intermediate filament(GO:0005882)
0.1	1.3	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.1	0.3	GO:0038039	G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1	0.2	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.6	GO:0036156	inner dynein arm(GO:0036156)
0.0	0.5	GO:0043596	nuclear replication fork(GO:0043596)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	2.6	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.4	GO:0043194	axon initial segment(GO:0043194)
0.0	1.9	GO:0016592	mediator complex(GO:0016592)
0.0	0.6	GO:0045180	basal cortex(GO:0045180)
0.0	3.6	GO:0072686	mitotic spindle(GO:0072686)
0.0	0.6	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	7.7	GO:0000793	condensed chromosome(GO:0000793)
0.0	3.2	GO:0030667	secretory granule membrane(GO:0030667)
0.0	0.4	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	15.3	GO:0016324	apical plasma membrane(GO:0016324)
0.0	0.6	GO:0031011	Ino80 complex(GO:0031011)
0.0	0.3	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.9	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	5.8	GO:0031225	anchored component of membrane(GO:0031225)
0.0	2.5	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.7	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	1.1	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	2.9	GO:0005604	basement membrane(GO:0005604)
0.0	0.6	GO:0000145	exocyst(GO:0000145)
0.0	1.1	GO:0008305	integrin complex(GO:0008305)
0.0	0.4	GO:0030057	desmosome(GO:0030057)
0.0	0.2	GO:0097346	INO80-type complex(GO:0097346)
0.0	7.0	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	2.0	GO:0005581	collagen trimer(GO:0005581)
0.0	1.6	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.2	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	3.1	GO:0005884	actin filament(GO:0005884)
0.0	0.8	GO:0031519	PcG protein complex(GO:0031519)
0.0	3.0	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.7	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	1.0	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.0	0.2	GO:0010369	chromocenter(GO:0010369)
0.0	0.2	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0044294	dendritic growth cone(GO:0044294)
0.0	1.1	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.7	GO:0005902	microvillus(GO:0005902)
0.0	0.1	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	1.3	GO:0030139	endocytic vesicle(GO:0030139)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	11.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
1.6	11.3	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.2	3.5	GO:0003987	acetate-CoA ligase activity(GO:0003987)
1.1	10.6	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
1.1	4.2	GO:2001069	glycogen binding(GO:2001069)
1.0	3.1	GO:0045159	myosin II binding(GO:0045159)
1.0	5.8	GO:0015265	urea channel activity(GO:0015265)
0.9	2.6	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
0.8	2.3	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.8	3.0	GO:0070052	collagen V binding(GO:0070052)
0.7	3.7	GO:0004966	galanin receptor activity(GO:0004966)
0.7	2.6	GO:1902379	chemoattractant activity involved in axon guidance(GO:1902379)
0.6	23.0	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.6	4.0	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.5	5.6	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.4	8.7	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.4	2.9	GO:0001515	opioid peptide activity(GO:0001515)
0.4	6.6	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.4	9.7	GO:0070182	DNA polymerase binding(GO:0070182)
0.4	8.0	GO:0005212	structural constituent of eye lens(GO:0005212)
0.4	2.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.4	1.8	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3	1.4	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.3	1.0	GO:0035939	microsatellite binding(GO:0035939)
0.3	1.6	GO:0030280	structural constituent of epidermis(GO:0030280)
0.3	0.9	GO:0052594	tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.3	1.6	GO:0043515	kinetochore binding(GO:0043515)
0.3	1.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.3	1.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939) bradykinin receptor binding(GO:0031711)
0.3	2.1	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.3	1.3	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.3	1.1	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.3	4.9	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.2	1.9	GO:0048495	Roundabout binding(GO:0048495)
0.2	1.6	GO:0048101	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2	2.1	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.2	1.8	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.2	0.7	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.2	3.4	GO:0008301	DNA binding, bending(GO:0008301)
0.2	4.2	GO:0032036	myosin heavy chain binding(GO:0032036)
0.2	9.0	GO:0032452	histone demethylase activity(GO:0032452)
0.2	1.4	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.2	2.0	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2	3.0	GO:0015643	toxic substance binding(GO:0015643)
0.2	5.4	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
0.2	3.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.2	1.5	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.2	4.0	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2	1.3	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.2	2.5	GO:0051010	microtubule plus-end binding(GO:0051010)
0.2	2.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	2.2	GO:0048185	activin binding(GO:0048185)
0.1	1.5	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	0.7	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	12.3	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	0.8	GO:0004359	glutaminase activity(GO:0004359)
0.1	1.7	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.1	0.5	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.1	1.3	GO:0051870	methotrexate binding(GO:0051870)
0.1	0.7	GO:0001595	angiotensin receptor activity(GO:0001595)
0.1	0.8	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1	0.7	GO:0004111	creatine kinase activity(GO:0004111)
0.1	0.9	GO:0043208	glycosphingolipid binding(GO:0043208)
0.1	1.9	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1	0.3	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.1	0.9	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.1	1.8	GO:0004806	triglyceride lipase activity(GO:0004806)
0.1	0.4	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.1	1.3	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1	0.3	GO:0005119	smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.1	0.7	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.1	0.6	GO:0032554	purine deoxyribonucleotide binding(GO:0032554)
0.1	0.8	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.1	1.7	GO:0004707	MAP kinase activity(GO:0004707)
0.1	0.9	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.2	GO:0009041	uridylate kinase activity(GO:0009041) nucleoside phosphate kinase activity(GO:0050145)
0.1	1.1	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1	0.7	GO:0097322	7SK snRNA binding(GO:0097322)
0.1	0.4	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.1	0.5	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.1	1.4	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1	0.5	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.1	1.6	GO:0001222	transcription corepressor binding(GO:0001222)
0.1	0.7	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.1	0.3	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1	1.2	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1	0.1	GO:0098770	FBXO family protein binding(GO:0098770)
0.1	3.0	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	1.8	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	0.4	GO:0046972	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1	2.2	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	0.4	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	9.6	GO:0017124	SH3 domain binding(GO:0017124)
0.0	4.5	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.4	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0	0.3	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.6	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.5	GO:0036310	annealing helicase activity(GO:0036310)
0.0	1.1	GO:1905030	voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.2	GO:0045322	unmethylated CpG binding(GO:0045322)
0.0	9.0	GO:0008017	microtubule binding(GO:0008017)
0.0	3.5	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	1.3	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.3	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.0	1.9	GO:0043621	protein self-association(GO:0043621)
0.0	1.0	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	1.1	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.2	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.0	1.1	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	1.5	GO:0070888	E-box binding(GO:0070888)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	17.8	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.6	GO:0015026	coreceptor activity(GO:0015026)
0.0	0.5	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.6	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	0.4	GO:0043236	laminin binding(GO:0043236)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.5	GO:0005351	sugar:proton symporter activity(GO:0005351)
0.0	0.2	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.3	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.6	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	6.2	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.2	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.9	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	1.1	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0	0.3	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	1.5	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	0.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.3	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.3	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	2.5	GO:0008236	serine-type peptidase activity(GO:0008236)
0.0	0.3	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.4	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	9.8	PID BARD1 PATHWAY	BARD1 signaling events
0.2	11.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	12.3	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	2.5	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	1.7	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	8.1	PID PLK1 PATHWAY	PLK1 signaling events
0.1	4.7	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.1	4.7	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	3.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	3.1	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	4.6	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.1	1.9	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	3.3	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	2.6	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	3.0	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	2.8	PID AURORA B PATHWAY	Aurora B signaling
0.1	3.0	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	2.9	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	6.0	PID P73PATHWAY	p73 transcription factor network
0.1	1.5	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	1.4	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.1	3.9	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	2.2	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	1.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	2.3	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	1.1	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	2.0	NABA COLLAGENS	Genes encoding collagen proteins
0.0	2.3	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.9	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.9	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.6	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	2.7	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.3	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	5.2	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.7	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	1.0	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.7	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.5	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.3	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.2	PID MYC PATHWAY	C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	10.7	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
1.1	22.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.7	8.8	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.6	3.5	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.4	14.5	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2	9.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.2	2.9	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.2	3.0	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	4.4	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	4.3	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.1	1.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	3.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	1.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	2.6	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	2.5	REACTOME KINESINS	Genes involved in Kinesins
0.1	10.3	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.1	1.5	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.1	1.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	1.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	1.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	4.9	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.1	3.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	11.1	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	0.9	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	0.7	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	5.4	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.8	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	4.0	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	1.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	1.5	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	4.0	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.8	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.8	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.5	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.5	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.2	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.8	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	2.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	1.3	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	1.7	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	1.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	1.9	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.8	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.8	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.3	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	2.0	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	1.1	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)