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GSE58827: Dynamics of the Mouse Liver

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Results for Gsc2_Dmbx1

Z-value: 0.75

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Transcription factors associated with Gsc2_Dmbx1

Gene Symbol Gene ID Gene Info
Gsc2
ENSMUSG00000022738.6 goosecoid homebox 2
Dmbx1
ENSMUSG00000028707.9 diencephalon/mesencephalon homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Dmbx1mm10_v2_chr4_-_115939923_115939928-0.344.4e-02Click!
Gsc2mm10_v2_chr16_-_17915059_17915059-0.202.5e-01Click!

Activity profile of Gsc2_Dmbx1 motif

Sorted Z-values of Gsc2_Dmbx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_37054818 5.65 ENSMUST00000120052.1
Lrit1
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
chr14_+_37068042 5.35 ENSMUST00000057176.3
Lrit2
leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
chr2_-_24049389 4.44 ENSMUST00000051416.5
Hnmt
histamine N-methyltransferase
chr2_+_102658640 3.96 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr2_+_102659213 3.88 ENSMUST00000111213.1
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr16_-_46010212 2.85 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr6_+_3993776 2.80 ENSMUST00000031673.5
Gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr7_-_15879844 2.51 ENSMUST00000172758.1
ENSMUST00000044434.6
Crx
cone-rod homeobox containing gene
chr14_-_118052235 2.43 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr7_+_43712505 2.33 ENSMUST00000066834.6
Klk13
kallikrein related-peptidase 13
chr14_+_29018205 2.03 ENSMUST00000055662.2
Lrtm1
leucine-rich repeats and transmembrane domains 1
chr7_+_13398115 1.81 ENSMUST00000005791.7
Cabp5
calcium binding protein 5
chr6_-_29380426 1.78 ENSMUST00000147483.2
Opn1sw
opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
chr15_-_101892916 1.72 ENSMUST00000100179.1
Krt76
keratin 76
chr4_-_59960659 1.68 ENSMUST00000075973.2
Mup4
major urinary protein 4
chr14_-_31640878 1.65 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
Hacl1
2-hydroxyacyl-CoA lyase 1
chr6_-_29380513 1.63 ENSMUST00000080428.6
Opn1sw
opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
chr16_-_17915059 1.59 ENSMUST00000012279.4
Gsc2
goosecoid homebox 2
chr5_-_87140318 1.51 ENSMUST00000067790.6
ENSMUST00000113327.1
Ugt2b5
UDP glucuronosyltransferase 2 family, polypeptide B5
chr9_+_50617516 1.42 ENSMUST00000141366.1
Pih1d2
PIH1 domain containing 2
chr8_+_13405080 1.34 ENSMUST00000033827.7
Grk1
G protein-coupled receptor kinase 1
chr7_-_80403315 1.29 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr6_+_136954521 1.15 ENSMUST00000137768.1
Pde6h
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr11_-_43901187 1.13 ENSMUST00000067258.2
ENSMUST00000139906.1
Adra1b
adrenergic receptor, alpha 1b
chr11_+_4031770 1.10 ENSMUST00000019512.7
Sec14l4
SEC14-like 4 (S. cerevisiae)
chrM_+_8600 1.05 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr11_-_68973840 0.99 ENSMUST00000038644.4
Rangrf
RAN guanine nucleotide release factor
chr8_-_95306585 0.92 ENSMUST00000119870.2
ENSMUST00000093268.4
Cngb1
cyclic nucleotide gated channel beta 1
chr7_-_25398697 0.90 ENSMUST00000105177.2
ENSMUST00000149349.1
Lipe
lipase, hormone sensitive
chr2_+_91259822 0.85 ENSMUST00000138470.1
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chrX_+_74424632 0.84 ENSMUST00000114129.2
ENSMUST00000132749.1
Ikbkg
inhibitor of kappaB kinase gamma
chr11_-_99285260 0.84 ENSMUST00000017255.3
Krt24
keratin 24
chr11_+_70459940 0.83 ENSMUST00000147289.1
ENSMUST00000126105.1
Zmynd15
zinc finger, MYND-type containing 15
chr19_-_12765447 0.82 ENSMUST00000112933.1
Cntf
ciliary neurotrophic factor
chr10_-_22149270 0.80 ENSMUST00000179054.1
ENSMUST00000069372.6
E030030I06Rik
RIKEN cDNA E030030I06 gene
chrX_+_160768013 0.78 ENSMUST00000033650.7
Rs1
retinoschisis (X-linked, juvenile) 1 (human)
chrX_+_160768179 0.75 ENSMUST00000112368.2
Rs1
retinoschisis (X-linked, juvenile) 1 (human)
chr7_-_19280032 0.74 ENSMUST00000032560.4
Ppm1n
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr2_+_121456963 0.74 ENSMUST00000126764.1
Hypk
huntingtin interacting protein K
chr9_-_50746501 0.71 ENSMUST00000034564.1
2310030G06Rik
RIKEN cDNA 2310030G06 gene
chr1_-_44218952 0.70 ENSMUST00000054801.3
Mettl21e
methyltransferase like 21E
chr8_+_78509319 0.65 ENSMUST00000034111.8
Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr2_+_105092018 0.65 ENSMUST00000111107.1
Gm11060
predicted gene 11060
chr11_+_5099406 0.63 ENSMUST00000134267.1
ENSMUST00000036320.5
ENSMUST00000150632.1
Rhbdd3
rhomboid domain containing 3
chr2_+_86297817 0.63 ENSMUST00000054746.2
Olfr1052
olfactory receptor 1052
chrM_+_7759 0.63 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chrX_+_38600626 0.62 ENSMUST00000000365.2
Mcts1
malignant T cell amplified sequence 1
chr14_+_64588112 0.62 ENSMUST00000181808.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr18_-_3299452 0.60 ENSMUST00000126578.1
Crem
cAMP responsive element modulator
chr9_+_99470440 0.60 ENSMUST00000056103.4
1600029I14Rik
RIKEN cDNA 1600029I14 gene
chr11_+_5099608 0.59 ENSMUST00000139742.1
Rhbdd3
rhomboid domain containing 3
chr18_-_20059478 0.56 ENSMUST00000075214.2
ENSMUST00000039247.4
Dsc2
desmocollin 2
chr15_+_4375462 0.54 ENSMUST00000061925.4
Plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr6_-_124840192 0.54 ENSMUST00000024206.5
Gnb3
guanine nucleotide binding protein (G protein), beta 3
chr19_+_26605106 0.52 ENSMUST00000025862.7
ENSMUST00000176030.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_164562579 0.52 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2
WAP four-disulfide core domain 2
chrX_+_7728439 0.51 ENSMUST00000033489.7
Praf2
PRA1 domain family 2
chr11_-_70459957 0.50 ENSMUST00000019064.2
Cxcl16
chemokine (C-X-C motif) ligand 16
chr7_-_127725616 0.49 ENSMUST00000076091.2
Ctf2
cardiotrophin 2
chr19_+_4139799 0.48 ENSMUST00000096338.3
Gpr152
G protein-coupled receptor 152
chr11_+_19924354 0.47 ENSMUST00000093299.6
Spred2
sprouty-related, EVH1 domain containing 2
chr1_-_168431695 0.47 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chr6_+_90269106 0.47 ENSMUST00000058039.2
Vmn1r54
vomeronasal 1 receptor 54
chr8_-_106136890 0.46 ENSMUST00000115979.2
Esrp2
epithelial splicing regulatory protein 2
chr11_+_109649376 0.45 ENSMUST00000106677.1
Prkar1a
protein kinase, cAMP dependent regulatory, type I, alpha
chr2_+_23068168 0.45 ENSMUST00000028121.7
ENSMUST00000114523.2
ENSMUST00000144088.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chrX_-_43167817 0.42 ENSMUST00000115058.1
ENSMUST00000115059.1
Tenm1
teneurin transmembrane protein 1
chr4_+_136622612 0.42 ENSMUST00000178843.1
Lactbl1
lactamase, beta-like 1
chr3_-_88461182 0.42 ENSMUST00000166237.1
Sema4a
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr6_-_59426279 0.40 ENSMUST00000051065.4
Gprin3
GPRIN family member 3
chr3_-_144849301 0.40 ENSMUST00000159989.1
Clca4
chloride channel calcium activated 4
chr5_-_96161990 0.39 ENSMUST00000155901.1
Cnot6l
CCR4-NOT transcription complex, subunit 6-like
chr11_-_70619194 0.39 ENSMUST00000102556.3
ENSMUST00000014753.8
Chrne
cholinergic receptor, nicotinic, epsilon polypeptide
chr2_-_51973219 0.38 ENSMUST00000028314.2
Nmi
N-myc (and STAT) interactor
chrX_+_48623737 0.38 ENSMUST00000114936.1
Slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr11_+_78322965 0.38 ENSMUST00000017534.8
Aldoc
aldolase C, fructose-bisphosphate
chr14_-_54617993 0.38 ENSMUST00000022803.4
Psmb5
proteasome (prosome, macropain) subunit, beta type 5
chr8_-_106136792 0.38 ENSMUST00000146940.1
Esrp2
epithelial splicing regulatory protein 2
chr7_+_126976338 0.35 ENSMUST00000032920.3
Cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr5_-_134456702 0.34 ENSMUST00000073161.5
ENSMUST00000171794.2
ENSMUST00000111245.2
ENSMUST00000100654.3
ENSMUST00000167084.2
ENSMUST00000100652.3
ENSMUST00000100650.3
ENSMUST00000074114.5
Gtf2ird1
general transcription factor II I repeat domain-containing 1
chr13_-_64497792 0.34 ENSMUST00000180282.1
1190003K10Rik
RIKEN cDNA 1190003K10 gene
chr2_-_30093642 0.34 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr7_-_107625161 0.34 ENSMUST00000060348.2
5330417H12Rik
RIKEN cDNA 5330417H12 gene
chr4_+_80834123 0.33 ENSMUST00000133655.1
ENSMUST00000006151.6
Tyrp1
tyrosinase-related protein 1
chrX_+_74424534 0.32 ENSMUST00000135165.1
ENSMUST00000114128.1
ENSMUST00000114133.2
ENSMUST00000004330.3
Ikbkg
inhibitor of kappaB kinase gamma
chr1_+_177444653 0.32 ENSMUST00000094276.3
Zbtb18
zinc finger and BTB domain containing 18
chr7_-_4514609 0.31 ENSMUST00000166959.1
Tnnt1
troponin T1, skeletal, slow
chr2_-_51972990 0.31 ENSMUST00000145481.1
ENSMUST00000112705.2
Nmi
N-myc (and STAT) interactor
chr5_+_3344194 0.31 ENSMUST00000042410.4
Cdk6
cyclin-dependent kinase 6
chr7_-_4514558 0.31 ENSMUST00000163538.1
Tnnt1
troponin T1, skeletal, slow
chr11_-_59187738 0.30 ENSMUST00000170895.2
Guk1
guanylate kinase 1
chr10_+_59403644 0.30 ENSMUST00000009790.7
Pla2g12b
phospholipase A2, group XIIB
chr3_-_8964037 0.29 ENSMUST00000091354.5
ENSMUST00000094381.4
Tpd52
tumor protein D52
chr11_+_113659283 0.28 ENSMUST00000137878.1
Cog1
component of oligomeric golgi complex 1
chr2_+_85769803 0.27 ENSMUST00000065626.2
Olfr1013
olfactory receptor 1013
chr6_+_119236507 0.26 ENSMUST00000037434.6
Cacna2d4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr2_-_104257400 0.25 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr3_+_103809520 0.24 ENSMUST00000076599.1
ENSMUST00000106824.1
ENSMUST00000106823.1
ENSMUST00000047285.2
Ap4b1
adaptor-related protein complex AP-4, beta 1
chr10_+_90576872 0.24 ENSMUST00000182550.1
ENSMUST00000099364.5
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr7_+_13398150 0.24 ENSMUST00000117400.1
Cabp5
calcium binding protein 5
chr2_-_30093607 0.23 ENSMUST00000081838.6
Zdhhc12
zinc finger, DHHC domain containing 12
chr16_-_35490873 0.22 ENSMUST00000023550.7
Pdia5
protein disulfide isomerase associated 5
chr14_-_55524938 0.22 ENSMUST00000178694.1
Nrl
neural retina leucine zipper gene
chrX_+_133908418 0.21 ENSMUST00000033606.8
ENSMUST00000113303.1
ENSMUST00000165805.1
Srpx2
sushi-repeat-containing protein, X-linked 2
chr7_-_105752193 0.21 ENSMUST00000033184.4
Tpp1
tripeptidyl peptidase I
chr14_-_55524975 0.21 ENSMUST00000062232.7
Nrl
neural retina leucine zipper gene
chr11_+_4186789 0.19 ENSMUST00000041042.6
ENSMUST00000180088.1
Tbc1d10a
TBC1 domain family, member 10a
chr2_+_67445994 0.19 ENSMUST00000112347.1
ENSMUST00000028410.3
Xirp2
xin actin-binding repeat containing 2
chr4_+_80834298 0.19 ENSMUST00000102831.1
Tyrp1
tyrosinase-related protein 1
chr5_+_3343893 0.19 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr2_+_101624696 0.19 ENSMUST00000044031.3
Rag2
recombination activating gene 2
chr17_-_71752867 0.18 ENSMUST00000057405.7
BC027072
cDNA sequence BC027072
chr13_-_21783391 0.17 ENSMUST00000099704.3
Hist1h3i
histone cluster 1, H3i
chr4_-_139833524 0.17 ENSMUST00000030508.7
Pax7
paired box gene 7
chr11_-_90687572 0.17 ENSMUST00000107869.2
ENSMUST00000154599.1
ENSMUST00000107868.1
ENSMUST00000020849.2
Tom1l1
target of myb1-like 1 (chicken)
chr4_+_102589687 0.17 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b
phosphodiesterase 4B, cAMP specific
chrX_+_57089312 0.17 ENSMUST00000114745.2
ENSMUST00000114746.1
Vgll1
vestigial like 1 homolog (Drosophila)
chr1_-_92473801 0.16 ENSMUST00000027478.6
Ndufa10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10
chr17_+_46910452 0.15 ENSMUST00000024773.5
Prph2
peripherin 2
chr11_-_69237022 0.15 ENSMUST00000021259.2
ENSMUST00000108665.1
ENSMUST00000108664.1
Gucy2e
guanylate cyclase 2e
chr5_+_77265454 0.15 ENSMUST00000080359.5
Rest
RE1-silencing transcription factor
chr13_-_116309639 0.13 ENSMUST00000036060.6
Isl1
ISL1 transcription factor, LIM/homeodomain
chr1_-_110977366 0.13 ENSMUST00000094626.3
Cdh19
cadherin 19, type 2
chr16_-_76403673 0.11 ENSMUST00000052867.7
Gm9843
predicted gene 9843
chr13_+_23752267 0.11 ENSMUST00000091703.2
Hist1h3b
histone cluster 1, H3b
chr6_-_142322941 0.10 ENSMUST00000128446.1
Slco1a5
solute carrier organic anion transporter family, member 1a5
chr10_+_21993890 0.10 ENSMUST00000092673.4
Sgk1
serum/glucocorticoid regulated kinase 1
chr11_+_67695314 0.10 ENSMUST00000021290.1
Rcvrn
recoverin
chr18_-_75697639 0.10 ENSMUST00000165559.1
Ctif
CBP80/20-dependent translation initiation factor
chr19_+_36083696 0.10 ENSMUST00000025714.7
Rpp30
ribonuclease P/MRP 30 subunit
chr10_+_18407658 0.09 ENSMUST00000037341.7
Nhsl1
NHS-like 1
chr10_+_80292453 0.08 ENSMUST00000068408.7
ENSMUST00000062674.6
Rps15
ribosomal protein S15
chr3_-_145099024 0.07 ENSMUST00000040465.6
Clca5
chloride channel calcium activated 5
chr7_-_109493627 0.07 ENSMUST00000106739.1
Trim66
tripartite motif-containing 66
chr19_+_43752996 0.06 ENSMUST00000026199.7
ENSMUST00000112047.3
ENSMUST00000153295.1
Cutc
cutC copper transporter homolog (E.coli)
chr19_+_12883855 0.05 ENSMUST00000049624.2
Olfr1445
olfactory receptor 1445
chr11_+_23256566 0.03 ENSMUST00000136235.1
Xpo1
exportin 1, CRM1 homolog (yeast)
chr7_-_98656530 0.03 ENSMUST00000038359.4
2210018M11Rik
RIKEN cDNA 2210018M11 gene
chr7_+_101969796 0.03 ENSMUST00000084852.5
Numa1
nuclear mitotic apparatus protein 1
chr7_+_64153916 0.02 ENSMUST00000107527.2
Trpm1
transient receptor potential cation channel, subfamily M, member 1
chr4_+_19280850 0.02 ENSMUST00000102999.1
Cngb3
cyclic nucleotide gated channel beta 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Gsc2_Dmbx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 7.8 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.0 3.0 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.9 4.4 GO:0001692 histamine metabolic process(GO:0001692)
0.4 1.3 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.4 1.5 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.4 1.1 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.3 1.3 GO:0090472 dibasic protein processing(GO:0090472)
0.3 3.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.3 1.6 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.2 0.7 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.2 0.9 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.2 0.8 GO:0048691 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.2 0.3 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.2 0.6 GO:0002188 translation reinitiation(GO:0002188)
0.1 3.7 GO:0007602 phototransduction(GO:0007602)
0.1 1.0 GO:0098909 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 1.7 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.4 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.1 1.2 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.1 0.3 GO:0046710 purine deoxyribonucleotide biosynthetic process(GO:0009153) GDP metabolic process(GO:0046710)
0.1 0.5 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.5 GO:0044838 cell quiescence(GO:0044838)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.1 GO:0071655 macrophage colony-stimulating factor production(GO:0036301) granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655) regulation of macrophage colony-stimulating factor production(GO:1901256)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.5 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 1.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.6 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.0 0.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 1.1 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.5 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 2.0 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.8 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.4 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.5 GO:0019236 response to pheromone(GO:0019236)
0.0 1.1 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 3.1 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.4 GO:0007274 synaptic transmission, cholinergic(GO:0007271) neuromuscular synaptic transmission(GO:0007274)
0.0 3.7 GO:0016042 lipid catabolic process(GO:0016042)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 7.8 GO:0030673 axolemma(GO:0030673)
0.1 3.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 7.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.3 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 1.7 GO:0045095 keratin filament(GO:0045095)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 5.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.5 GO:0005861 troponin complex(GO:0005861)
0.0 2.7 GO:0014704 intercalated disc(GO:0014704)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 7.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 3.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.4 1.2 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.3 1.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.3 1.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.2 2.9 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 1.6 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.2 0.9 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 0.5 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 1.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 1.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 2.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.5 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.5 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 1.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.5 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.5 GO:0031014 troponin T binding(GO:0031014)
0.1 0.8 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.7 GO:0005550 pheromone binding(GO:0005550)
0.1 1.1 GO:0030553 cGMP binding(GO:0030553)
0.1 1.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.9 GO:0043855 cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 4.4 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.3 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 1.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.9 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 3.5 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.4 GO:0042166 acetylcholine binding(GO:0042166)
0.0 1.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.6 GO:0005549 odorant binding(GO:0005549)
0.0 2.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0030332 cyclin binding(GO:0030332)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.7 GO:0030145 manganese ion binding(GO:0030145)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 1.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.4 3.4 REACTOME OPSINS Genes involved in Opsins
0.1 7.8 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.7 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME G1 PHASE Genes involved in G1 Phase