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GSE58827: Dynamics of the Mouse Liver

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Results for Gsx2_Hoxd3_Vax1

Z-value: 0.82

Motif logo

Transcription factors associated with Gsx2_Hoxd3_Vax1

Gene Symbol Gene ID Gene Info
ENSMUSG00000035946.6 GS homeobox 2
ENSMUSG00000079277.3 homeobox D3
ENSMUSG00000006270.6 ventral anterior homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Vax1mm10_v2_chr19_-_59170978_59170978-0.572.8e-04Click!
Hoxd3mm10_v2_chr2_+_74711911_74711939-0.391.8e-02Click!

Activity profile of Gsx2_Hoxd3_Vax1 motif

Sorted Z-values of Gsx2_Hoxd3_Vax1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_127898515 13.20 ENSMUST00000047134.7
4short chain dehydrogenase/reductase family 9C, member 7
chr1_+_130826762 9.21 ENSMUST00000133792.1
polymeric immunoglobulin receptor
chr19_-_7966000 6.58 ENSMUST00000182102.1
ENSMUST00000075619.4
solute carrier family 22, member 27
chr7_-_48843663 4.80 ENSMUST00000167786.2
cysteine and glycine-rich protein 3
chr2_+_109917639 3.77 ENSMUST00000046548.7
ENSMUST00000111037.2
leucine-rich repeat-containing G protein-coupled receptor 4
chr2_+_116067213 3.72 ENSMUST00000152412.1
RIKEN cDNA G630016G05 gene
chr18_+_56432116 3.24 ENSMUST00000070166.5
GRAM domain containing 3
chr1_+_88211956 2.91 ENSMUST00000073049.6
UDP glucuronosyltransferase 1 family, polypeptide A1
chr15_-_101892916 2.70 ENSMUST00000100179.1
keratin 76
chr10_+_63024315 2.67 ENSMUST00000124784.1
phenazine biosynthesis-like protein domain containing 2
chr18_-_75697639 2.66 ENSMUST00000165559.1
CBP80/20-dependent translation initiation factor
chr17_+_85028347 2.37 ENSMUST00000024944.7
solute carrier family 3, member 1
chr4_+_102589687 2.13 ENSMUST00000097949.4
ENSMUST00000106901.1
phosphodiesterase 4B, cAMP specific
chrX_-_143933089 2.07 ENSMUST00000087313.3
doublecortin
chr3_-_131303144 1.94 ENSMUST00000106337.2
cytochrome P450, family 2, subfamily u, polypeptide 1
chr4_+_133553370 1.91 ENSMUST00000042706.2
nuclear receptor subfamily 0, group B, member 2
chr10_+_63024512 1.87 ENSMUST00000020262.4
phenazine biosynthesis-like protein domain containing 2
chr19_-_8218832 1.82 ENSMUST00000113298.2
solute carrier family 22. member 29
chr16_+_22918378 1.74 ENSMUST00000170805.1
fetuin beta
chr4_-_14621669 1.72 ENSMUST00000143105.1
solute carrier family 26, member 7
chr18_+_12741324 1.58 ENSMUST00000115857.2
ENSMUST00000121018.1
ENSMUST00000119108.1
calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)
chr10_+_128083273 1.57 ENSMUST00000026459.5
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr5_-_62766153 1.47 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_+_114851142 1.44 ENSMUST00000133245.1
ENSMUST00000122967.2
G protein-coupled receptor, family C, group 5, member C
chr11_+_114851507 1.43 ENSMUST00000177952.1
G protein-coupled receptor, family C, group 5, member C
chrX_+_160768179 1.39 ENSMUST00000112368.2
retinoschisis (X-linked, juvenile) 1 (human)
chrM_+_14138 1.36 ENSMUST00000082421.1
mitochondrially encoded cytochrome b
chr12_-_98577940 1.35 ENSMUST00000110113.1
potassium channel, subfamily K, member 10
chrX_+_160768013 1.35 ENSMUST00000033650.7
retinoschisis (X-linked, juvenile) 1 (human)
chrX_+_107255878 1.35 ENSMUST00000101294.2
ENSMUST00000118820.1
ENSMUST00000120971.1
G protein-coupled receptor 174
chr9_+_121950988 1.33 ENSMUST00000043011.7
family with sequence similarity 198, member A
chr6_-_130026954 1.33 ENSMUST00000074056.2
killer cell lectin-like receptor, subfamily A, member 6
chr8_+_36489191 1.32 ENSMUST00000171777.1
RIKEN cDNA 6430573F11 gene
chr8_+_45658666 1.23 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
sorbin and SH3 domain containing 2
chr14_-_64455903 1.22 ENSMUST00000067927.7
methionine sulfoxide reductase A
chr15_+_25773985 1.20 ENSMUST00000125667.1
myosin X
chr3_+_138313279 1.18 ENSMUST00000013455.6
ENSMUST00000106247.1
alcohol dehydrogenase 6A (class V)
chr15_-_101802343 1.17 ENSMUST00000063292.6
keratin 73
chr4_-_42661893 1.17 ENSMUST00000108006.3
interleukin 11 receptor, alpha chain 2
chrM_-_14060 1.15 ENSMUST00000082419.1
mitochondrially encoded NADH dehydrogenase 6
chr5_+_87000838 1.11 ENSMUST00000031186.7
UDP glucuronosyltransferase 2 family, polypeptide B35
chr9_+_32116040 1.10 ENSMUST00000174641.1
Rho GTPase activating protein 32
chr2_+_69897220 1.09 ENSMUST00000055758.9
ENSMUST00000112251.2
ubiquitin protein ligase E3 component n-recognin 3
chr5_+_87666200 1.08 ENSMUST00000094641.4
casein alpha s1
chr14_+_48446128 1.03 ENSMUST00000124720.1
transmembrane protein 260
chr5_-_62765618 1.02 ENSMUST00000159470.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_-_99374895 1.02 ENSMUST00000006963.2
keratin 28
chrM_+_9870 0.94 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr1_+_88055377 0.93 ENSMUST00000138182.1
ENSMUST00000113142.3
UDP glycosyltransferase 1 family, polypeptide A10
chr11_-_49113757 0.93 ENSMUST00000060398.1
olfactory receptor 1396
chr1_+_88055467 0.92 ENSMUST00000173325.1
UDP glycosyltransferase 1 family, polypeptide A10
chr4_-_14621494 0.91 ENSMUST00000149633.1
solute carrier family 26, member 7
chrM_+_10167 0.90 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr2_+_91457501 0.89 ENSMUST00000028689.3
low density lipoprotein receptor-related protein 4
chr19_-_39649046 0.88 ENSMUST00000067328.6
cytochrome P450, family 2, subfamily c, polypeptide 67
chr9_-_97369958 0.84 ENSMUST00000035026.4
tripartite motif-containing 42
chr14_+_47298260 0.82 ENSMUST00000166743.1
mitogen-activated protein kinase 1 interacting protein 1-like
chr4_-_129227883 0.82 ENSMUST00000106051.1
expressed sequence C77080
chr4_+_100478806 0.81 ENSMUST00000133493.2
ENSMUST00000092730.3
ENSMUST00000106979.3
ubiquitin-conjugating enzyme E2U (putative)
chr7_-_24724237 0.80 ENSMUST00000081657.4
predicted gene 4763
chr8_+_45658731 0.80 ENSMUST00000143820.1
ENSMUST00000132139.1
sorbin and SH3 domain containing 2
chr6_-_125380793 0.78 ENSMUST00000042647.6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr15_-_37459327 0.78 ENSMUST00000119730.1
ENSMUST00000120746.1
neurocalcin delta
chr1_-_24612700 0.77 ENSMUST00000088336.1
predicted gene 10222
chr6_-_130193112 0.76 ENSMUST00000112032.1
ENSMUST00000071554.2
killer cell lectin-like receptor subfamily A, member 9
chr13_-_17694729 0.75 ENSMUST00000068545.4
RIKEN cDNA 5033411D12 gene
chr11_-_73326807 0.74 ENSMUST00000134079.1
aspartoacylase
chr2_-_164613600 0.73 ENSMUST00000094351.4
ENSMUST00000109338.1
WAP four-disulfide core domain 8
chr2_+_164613519 0.71 ENSMUST00000094346.2
WAP four-disulfide core domain 6B
chr10_-_8886033 0.69 ENSMUST00000015449.5
SAM and SH3 domain containing 1
chr14_-_100149764 0.69 ENSMUST00000097079.4
Kruppel-like factor 12
chr4_-_148152059 0.68 ENSMUST00000056965.5
ENSMUST00000168503.1
ENSMUST00000152098.1
F-box protein 6
chr2_+_69897255 0.68 ENSMUST00000131553.1
ubiquitin protein ligase E3 component n-recognin 3
chr12_+_31184623 0.66 ENSMUST00000179160.1
RIKEN cDNA 6030469F06 gene
chrX_-_143933204 0.66 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
doublecortin
chr1_-_141257158 0.66 ENSMUST00000179202.1
predicted gene 4845
chr3_+_5218516 0.66 ENSMUST00000175866.1
zinc finger homeodomain 4
chr6_-_136875794 0.66 ENSMUST00000032342.1
matrix Gla protein
chr15_-_8710734 0.65 ENSMUST00000005493.7
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_+_95557494 0.65 ENSMUST00000079223.4
ENSMUST00000177394.1
FGGY carbohydrate kinase domain containing
chr5_-_84417359 0.64 ENSMUST00000113401.1
Eph receptor A5
chr13_+_19342154 0.63 ENSMUST00000103566.3
T cell receptor gamma, constant 4
chr6_+_37870786 0.63 ENSMUST00000120428.1
ENSMUST00000031859.7
tripartite motif-containing 24
chr16_-_45724600 0.63 ENSMUST00000096057.4
transgelin 3
chr6_-_130129898 0.62 ENSMUST00000014476.5
killer cell lectin-like receptor, subfamily A, member 8
chr9_-_70934808 0.62 ENSMUST00000034731.8
lipase, hepatic
chr4_+_95967205 0.62 ENSMUST00000030306.7
hook homolog 1 (Drosophila)
chr1_+_75435930 0.61 ENSMUST00000037796.7
ENSMUST00000113584.1
ENSMUST00000145166.1
ENSMUST00000143730.1
ENSMUST00000133418.1
ENSMUST00000144874.1
ENSMUST00000140287.1
GDP-mannose pyrophosphorylase A
chr1_+_75436002 0.60 ENSMUST00000131545.1
ENSMUST00000141124.1
GDP-mannose pyrophosphorylase A
chr11_-_73326472 0.59 ENSMUST00000155630.2
aspartoacylase
chr8_-_86580664 0.59 ENSMUST00000131423.1
ENSMUST00000152438.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 12
chr14_-_48662740 0.59 ENSMUST00000122009.1
orthodenticle homolog 2 (Drosophila)
chr12_+_111814170 0.59 ENSMUST00000021714.7
zinc finger, FYVE domain containing 21
chr11_+_116843278 0.59 ENSMUST00000106370.3
methyltransferase like 23
chrX_-_99470672 0.58 ENSMUST00000113797.3
ENSMUST00000113790.1
ENSMUST00000036354.6
ENSMUST00000167246.1
praja1, RING-H2 motif containing
chr15_-_82794236 0.57 ENSMUST00000006094.4
cytochrome P450, family 2, subfamily d, polypeptide 26
chr9_-_103222063 0.57 ENSMUST00000170904.1
transferrin
chr4_+_108719649 0.57 ENSMUST00000178992.1
RIKEN cDNA 3110021N24 gene
chr7_-_14123042 0.56 ENSMUST00000098809.2
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 3
chr15_-_8710409 0.54 ENSMUST00000157065.1
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_-_88675190 0.54 ENSMUST00000133532.1
ENSMUST00000150438.1
G-rich RNA sequence binding factor 1
chr4_-_15149755 0.52 ENSMUST00000108273.1
N-terminal EF-hand calcium binding protein 1
chr2_+_91257323 0.52 ENSMUST00000111349.2
ENSMUST00000131711.1
protein kinase C and casein kinase substrate in neurons 3
chr9_+_72958785 0.51 ENSMUST00000098567.2
ENSMUST00000034734.8
dyslexia susceptibility 1 candidate 1 homolog (human)
chr13_-_53473074 0.50 ENSMUST00000021922.8
msh homeobox 2
chrM_+_7759 0.50 ENSMUST00000082407.1
ENSMUST00000082408.1
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr14_+_56887795 0.49 ENSMUST00000022511.8
zinc finger, MYM-type 2
chr9_+_110052016 0.49 ENSMUST00000164930.1
ENSMUST00000163979.1
microtubule-associated protein 4
chr3_-_15426427 0.49 ENSMUST00000099201.3
signal-regulatory protein beta 1A
chr8_-_41016749 0.48 ENSMUST00000117735.1
mitochondrial tumor suppressor 1
chr11_+_75532099 0.48 ENSMUST00000169547.2
solute carrier family 43, member 2
chr11_+_58171648 0.48 ENSMUST00000020820.1
mitochondrial ribosomal protein L22
chr10_-_83648631 0.48 ENSMUST00000146876.2
ENSMUST00000176294.1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr2_-_28916412 0.47 ENSMUST00000050776.2
ENSMUST00000113849.1
BarH-like 1 (Drosophila)
chr16_-_32877723 0.47 ENSMUST00000119810.1
RIKEN cDNA 1700021K19 gene
chr2_+_20737306 0.47 ENSMUST00000114606.1
ENSMUST00000114608.1
enhancer trap locus 4
chr13_-_56482246 0.46 ENSMUST00000022019.3
interleukin 9
chr2_-_28916668 0.46 ENSMUST00000113847.1
BarH-like 1 (Drosophila)
chr7_+_38183217 0.45 ENSMUST00000165308.1
RIKEN cDNA 1600014C10 gene
chr8_-_41041828 0.44 ENSMUST00000051379.7
mitochondrial tumor suppressor 1
chr9_-_55919605 0.44 ENSMUST00000037408.8
S phase cyclin A-associated protein in the ER
chr8_-_13890233 0.44 ENSMUST00000033839.7
coordinator of PRMT5, differentiation stimulator
chr2_+_19371636 0.43 ENSMUST00000023856.8
methionine sulfoxide reductase B2
chr6_-_149101674 0.42 ENSMUST00000111557.1
DENN/MADD domain containing 5B
chr14_+_69347587 0.41 ENSMUST00000064831.5
ectonucleoside triphosphate diphosphohydrolase 4
chr10_+_128337761 0.40 ENSMUST00000005826.7
citrate synthase
chr16_-_16600533 0.40 ENSMUST00000159542.1
FYVE, RhoGEF and PH domain containing 4
chr5_-_108795352 0.40 ENSMUST00000004943.1
transmembrane emp24 protein transport domain containing
chr19_-_39812744 0.40 ENSMUST00000162507.1
ENSMUST00000160476.1
cytochrome P450, family 2, subfamily c, polypeptide 40
chr5_-_3647806 0.39 ENSMUST00000119783.1
ENSMUST00000007559.8
GATA zinc finger domain containing 1
chr15_+_41830921 0.39 ENSMUST00000166917.1
oxidation resistance 1
chr12_+_80644212 0.38 ENSMUST00000085245.5
solute carrier family 39 (zinc transporter), member 9
chr9_+_110476985 0.38 ENSMUST00000084948.4
ENSMUST00000061155.6
ENSMUST00000140686.1
ENSMUST00000084952.5
kinesin family member 9
chr13_-_102905740 0.38 ENSMUST00000167462.1
microtubule associated serine/threonine kinase family member 4
chr7_+_19368498 0.38 ENSMUST00000132655.1
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr14_+_53845234 0.38 ENSMUST00000103674.4
T cell receptor alpha variable 19
chr9_-_50659780 0.37 ENSMUST00000034567.3
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr6_+_8948608 0.37 ENSMUST00000160300.1
neurexophilin 1
chr4_-_150914401 0.37 ENSMUST00000105675.1
Parkinson disease (autosomal recessive, early onset) 7
chr5_+_104202609 0.37 ENSMUST00000066708.5
dentin matrix protein 1
chr13_-_67332525 0.36 ENSMUST00000168892.1
ENSMUST00000109735.2
zinc finger protein 595
chr8_-_121541939 0.35 ENSMUST00000034265.4
RIKEN cDNA 1700018B08 gene
chr6_+_63255971 0.35 ENSMUST00000159561.1
ENSMUST00000095852.3
glutamate receptor, ionotropic, delta 2
chr6_-_30693676 0.34 ENSMUST00000169422.1
ENSMUST00000115131.1
ENSMUST00000115130.2
ENSMUST00000031810.8
centrosomal protein 41
chr18_+_77332394 0.34 ENSMUST00000148341.1
lipoxygenase homology domains 1
chr12_-_84617326 0.34 ENSMUST00000021666.4
ATP-binding cassette, sub-family D (ALD), member 4
chr17_-_70853482 0.33 ENSMUST00000118283.1
TGFB-induced factor homeobox 1
chr13_-_49945335 0.33 ENSMUST00000178715.1
predicted pseudogene 10784
chr5_-_63968867 0.32 ENSMUST00000154169.1
RELT-like 1
chr9_+_37208291 0.31 ENSMUST00000034632.8
transmembrane protein 218
chrX_-_160138375 0.31 ENSMUST00000033662.8
pyruvate dehydrogenase E1 alpha 1
chr14_+_26693267 0.30 ENSMUST00000022433.4
dynein, axonemal, heavy chain 12
chr11_+_59306920 0.30 ENSMUST00000000128.3
ENSMUST00000108783.3
wingless-type MMTV integration site 9A
chr11_+_101087277 0.29 ENSMUST00000107302.1
ENSMUST00000107303.3
ENSMUST00000017945.8
ENSMUST00000149597.1
MAX-like protein X
chr3_-_117077760 0.29 ENSMUST00000029642.5
RIKEN cDNA 1700061I17 gene
chr15_+_39006272 0.29 ENSMUST00000179165.1
ENSMUST00000022906.7
frizzled homolog 6 (Drosophila)
chr4_+_145670685 0.28 ENSMUST00000105738.2
predicted gene 13242
chr4_-_45532470 0.28 ENSMUST00000147448.1
src homology 2 domain-containing transforming protein B
chr9_+_27299205 0.28 ENSMUST00000115247.1
ENSMUST00000133213.1
immunoglobulin superfamily, member 9B
chr16_-_97763712 0.28 ENSMUST00000019386.8
receptor-interacting serine-threonine kinase 4
chrX_+_37493428 0.27 ENSMUST00000115179.3
reproductive homeobox 2D
chr12_+_87874070 0.27 ENSMUST00000110147.2
predicted gene 2016
chr9_+_94669876 0.27 ENSMUST00000033463.9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr14_+_64589802 0.27 ENSMUST00000180610.1
RIKEN cDNA A930011O12 gene
chr18_+_33464163 0.27 ENSMUST00000097634.3
predicted gene 10549
chr1_-_163725123 0.26 ENSMUST00000159679.1
methyltransferase like 11B
chr16_-_92400067 0.25 ENSMUST00000023672.8
regulator of calcineurin 1
chr7_-_8161654 0.25 ENSMUST00000168807.2
vomeronasal 2, receptor 41
chr11_+_73371246 0.24 ENSMUST00000120401.1
ENSMUST00000078952.2
ENSMUST00000170592.1
ENSMUST00000127789.1
olfactory receptor 376
chr3_+_66219909 0.24 ENSMUST00000029421.5
pentraxin related gene
chr8_-_109251698 0.23 ENSMUST00000079189.3
RIKEN cDNA 4922502B01 gene
chr9_-_110476637 0.23 ENSMUST00000111934.1
ENSMUST00000068025.6
kelch-like 18
chr5_-_136986829 0.22 ENSMUST00000034953.7
ENSMUST00000085941.5
zinc finger, HIT domain containing 1
chr1_+_88306731 0.22 ENSMUST00000040210.7
transient receptor potential cation channel, subfamily M, member 8
chrM_+_8600 0.21 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr3_+_19187321 0.21 ENSMUST00000130806.1
ENSMUST00000117529.1
ENSMUST00000119865.1
mitochondrial fission regulator 1
chr1_-_161070613 0.20 ENSMUST00000035430.3
aspartyl-tRNA synthetase 2 (mitochondrial)
chr18_+_37355271 0.20 ENSMUST00000051163.1
protocadherin beta 8
chrX_+_37530452 0.19 ENSMUST00000072167.3
ENSMUST00000184746.1
reproductive homeobox 2E
chr5_-_106926245 0.19 ENSMUST00000117588.1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr6_+_134640940 0.19 ENSMUST00000062755.8
loss of heterozygosity, 12, chromosomal region 1 homolog (human)
chrX_+_37412067 0.19 ENSMUST00000115191.4
reproductive homeobox 2B
chrX_+_37244976 0.18 ENSMUST00000063340.5
ENSMUST00000173650.1
reproductive homeobox 2A
chr16_+_32877775 0.18 ENSMUST00000023489.4
ENSMUST00000171325.1
forty-two-three domain containing 1
chr7_-_9223653 0.17 ENSMUST00000072787.4
vomeronasal 2, receptor 37
chr8_+_21839926 0.17 ENSMUST00000006745.3
defensin beta 2
chr16_-_50330987 0.16 ENSMUST00000114488.1
bobby sox homolog (Drosophila)
chr11_+_90883320 0.16 ENSMUST00000142163.1
ENSMUST00000132218.1
RIKEN cDNA 4930405D11 gene
chr3_+_125404292 0.16 ENSMUST00000144344.1
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr9_-_85749308 0.15 ENSMUST00000039213.8
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr7_-_7689513 0.15 ENSMUST00000173459.1
vomeronasal 2, receptor 34
chr3_+_53488677 0.15 ENSMUST00000029307.3
stomatin (Epb7.2)-like 3
chr18_+_52615908 0.14 ENSMUST00000072666.3
zinc finger protein 474
chr4_-_14621805 0.14 ENSMUST00000042221.7
solute carrier family 26, member 7
chr1_-_83038431 0.14 ENSMUST00000164473.1
ENSMUST00000045560.8
solute carrier family 19, member 3
chr3_-_33082004 0.14 ENSMUST00000108225.3
peroxisomal biogenesis factor 5-like
chr1_-_33814516 0.13 ENSMUST00000044455.5
ENSMUST00000115167.1
zinc finger protein 451
chr18_+_57142782 0.13 ENSMUST00000139892.1
multiple EGF-like-domains 10
chr3_+_92992213 0.13 ENSMUST00000090863.3
late cornified envelope 3F
chr3_-_64565298 0.13 ENSMUST00000176481.1
vomeronasal 2, receptor 6

Network of associatons between targets according to the STRING database.

First level regulatory network of Gsx2_Hoxd3_Vax1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.2 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
1.6 4.8 GO:1903919 regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919)
1.3 3.8 GO:0060995 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
1.0 2.9 GO:0018879 biphenyl metabolic process(GO:0018879)
0.7 2.7 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.6 8.4 GO:0015747 urate transport(GO:0015747)
0.4 1.8 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.3 2.8 GO:0019532 oxalate transport(GO:0019532)
0.3 1.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.3 0.8 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.2 0.7 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.2 1.4 GO:0033762 response to glucagon(GO:0033762)
0.2 1.6 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.2 1.3 GO:0006083 acetate metabolic process(GO:0006083)
0.2 0.9 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.2 2.7 GO:0048733 sebaceous gland development(GO:0048733)
0.2 1.9 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 2.1 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 2.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.4 GO:1903189 enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.1 1.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.4 GO:0030091 protein repair(GO:0030091)
0.1 0.6 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.6 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.7 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.4 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 1.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.4 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.6 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 2.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 0.6 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.1 0.6 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.8 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 1.6 GO:0048240 sperm capacitation(GO:0048240)
0.1 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.4 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.0 0.6 GO:0019321 pentose metabolic process(GO:0019321)
0.0 1.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0001878 response to yeast(GO:0001878)
0.0 0.7 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 1.4 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.3 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:0015888 thiamine transport(GO:0015888)
0.0 0.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.0 0.1 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.0 0.4 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.3 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.5 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 1.3 GO:0043029 T cell homeostasis(GO:0043029)
0.0 1.3 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.9 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.0 0.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 2.9 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816) recognition of apoptotic cell(GO:0043654)
0.0 1.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.5 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 14.0 GO:0055114 oxidation-reduction process(GO:0055114)
0.0 0.6 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.4 GO:0071801 regulation of podosome assembly(GO:0071801)
0.0 1.2 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.8 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.2 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 8.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 1.6 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.4 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.1 0.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 1.4 GO:0045275 respiratory chain complex III(GO:0045275)
0.1 3.9 GO:0045095 keratin filament(GO:0045095)
0.1 0.8 GO:0033503 HULC complex(GO:0033503)
0.1 0.6 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.6 GO:0070695 FHF complex(GO:0070695)
0.1 1.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 2.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.9 GO:0016600 flotillin complex(GO:0016600)
0.1 0.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 3.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 3.4 GO:0070469 respiratory chain(GO:0070469)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0036156 inner dynein arm(GO:0036156)
0.0 4.2 GO:0030018 Z disc(GO:0030018)
0.0 2.4 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 16.7 GO:0005730 nucleolus(GO:0005730)
0.0 1.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0005118 sevenless binding(GO:0005118)
0.9 9.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.8 4.8 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.6 13.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.6 8.4 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.4 1.3 GO:0019807 aspartoacylase activity(GO:0019807)
0.4 1.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.3 1.6 GO:0043532 angiostatin binding(GO:0043532)
0.2 2.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 3.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.2 1.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2 0.6 GO:0019150 D-ribulokinase activity(GO:0019150)
0.2 1.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 1.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 2.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 5.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.7 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.4 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 1.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.6 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 3.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.6 GO:0034056 estrogen response element binding(GO:0034056)
0.1 1.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.6 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.6 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.1 2.5 GO:0070330 aromatase activity(GO:0070330)
0.1 1.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.6 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.4 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 2.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.9 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 2.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 4.6 GO:0016853 isomerase activity(GO:0016853)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 1.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.0 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 9.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 2.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.5 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 1.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 0.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 2.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 2.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 2.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.7 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins