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GSE58827: Dynamics of the Mouse Liver

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Results for Hmx1

Z-value: 1.48

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Transcription factors associated with Hmx1

Gene Symbol Gene ID Gene Info
Hmx1
ENSMUSG00000067438.3 H6 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hmx1mm10_v2_chr5_+_35388844_353888820.326.0e-02Click!

Activity profile of Hmx1 motif

Sorted Z-values of Hmx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_56102458 16.48 ENSMUST00000015583.1
Ctsg
cathepsin G
chr12_+_109459843 12.74 ENSMUST00000173812.1
Dlk1
delta-like 1 homolog (Drosophila)
chr14_-_79301623 10.44 ENSMUST00000022595.7
Rgcc
regulator of cell cycle
chr7_+_18884679 8.14 ENSMUST00000032573.6
Pglyrp1
peptidoglycan recognition protein 1
chr4_+_120666562 6.98 ENSMUST00000094814.4
Cited4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr17_-_33890539 6.74 ENSMUST00000173386.1
Kifc1
kinesin family member C1
chr6_+_30738044 6.68 ENSMUST00000128398.1
ENSMUST00000163949.2
ENSMUST00000124665.1
Mest
mesoderm specific transcript
chr13_+_91461050 6.61 ENSMUST00000004094.8
ENSMUST00000042122.8
Ssbp2
single-stranded DNA binding protein 2
chr17_-_33890584 6.46 ENSMUST00000114361.2
ENSMUST00000173492.1
Kifc1
kinesin family member C1
chr11_+_69965396 6.27 ENSMUST00000018713.6
Cldn7
claudin 7
chr8_-_122460666 5.65 ENSMUST00000006762.5
Snai3
snail homolog 3 (Drosophila)
chr1_-_75505641 5.54 ENSMUST00000155084.1
Obsl1
obscurin-like 1
chr1_-_75506331 5.24 ENSMUST00000113567.2
ENSMUST00000113565.2
Obsl1
obscurin-like 1
chr11_+_61956779 5.10 ENSMUST00000049836.7
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chrX_+_50841434 5.08 ENSMUST00000114887.2
2610018G03Rik
RIKEN cDNA 2610018G03 gene
chr6_+_90619241 5.08 ENSMUST00000032177.8
Slc41a3
solute carrier family 41, member 3
chr4_-_152477433 5.02 ENSMUST00000159186.1
ENSMUST00000162017.1
ENSMUST00000030768.2
Kcnab2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr17_-_71310952 4.94 ENSMUST00000024849.9
Emilin2
elastin microfibril interfacer 2
chr1_+_43730593 4.83 ENSMUST00000027217.8
1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr11_+_11686213 4.79 ENSMUST00000076700.4
ENSMUST00000048122.6
Ikzf1
IKAROS family zinc finger 1
chr6_+_29433248 4.78 ENSMUST00000101617.2
ENSMUST00000065090.5
Flnc
filamin C, gamma
chr17_+_26917091 4.76 ENSMUST00000078961.4
Kifc5b
kinesin family member C5B
chr14_-_56234650 4.51 ENSMUST00000015585.2
Gzmc
granzyme C
chr3_-_152166230 4.51 ENSMUST00000046614.9
Gipc2
GIPC PDZ domain containing family, member 2
chrX_-_7671341 4.42 ENSMUST00000033486.5
Plp2
proteolipid protein 2
chr6_-_67535783 4.41 ENSMUST00000058178.4
Tacstd2
tumor-associated calcium signal transducer 2
chr2_+_153492790 4.20 ENSMUST00000109783.1
4930404H24Rik
RIKEN cDNA 4930404H24 gene
chr12_+_35992900 4.18 ENSMUST00000020898.5
Agr2
anterior gradient 2
chr6_+_29433131 3.81 ENSMUST00000090474.4
Flnc
filamin C, gamma
chr3_+_28781305 3.75 ENSMUST00000060500.7
Eif5a2
eukaryotic translation initiation factor 5A2
chrX_-_134808984 3.74 ENSMUST00000035559.4
Armcx2
armadillo repeat containing, X-linked 2
chr9_-_42124276 3.67 ENSMUST00000060989.8
Sorl1
sortilin-related receptor, LDLR class A repeats-containing
chr9_+_108560422 3.64 ENSMUST00000081111.8
Impdh2
inosine 5'-phosphate dehydrogenase 2
chr2_-_92370999 3.56 ENSMUST00000176810.1
ENSMUST00000090582.4
Gyltl1b
glycosyltransferase-like 1B
chr14_+_54640952 3.52 ENSMUST00000169818.2
Gm17606
predicted gene, 17606
chr12_+_110279228 3.48 ENSMUST00000097228.4
Dio3
deiodinase, iodothyronine type III
chr2_-_92371039 3.47 ENSMUST00000068586.6
Gyltl1b
glycosyltransferase-like 1B
chr11_-_46312220 3.41 ENSMUST00000129474.1
ENSMUST00000093166.4
ENSMUST00000165599.2
Cyfip2
cytoplasmic FMR1 interacting protein 2
chr11_+_3290300 3.34 ENSMUST00000057089.6
ENSMUST00000093402.5
Patz1
POZ (BTB) and AT hook containing zinc finger 1
chrX_-_74246364 3.26 ENSMUST00000130007.1
Flna
filamin, alpha
chr2_+_129198757 3.23 ENSMUST00000028880.3
Slc20a1
solute carrier family 20, member 1
chr8_+_105297663 3.22 ENSMUST00000015003.8
E2f4
E2F transcription factor 4
chrX_-_74246534 3.22 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna
filamin, alpha
chr7_-_126369543 3.17 ENSMUST00000032997.6
Lat
linker for activation of T cells
chr10_-_61273242 3.12 ENSMUST00000120336.1
Adamts14
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 14
chr6_-_124733067 3.04 ENSMUST00000173647.1
Ptpn6
protein tyrosine phosphatase, non-receptor type 6
chr6_-_127151044 3.04 ENSMUST00000000188.8
Ccnd2
cyclin D2
chr2_+_92915080 3.01 ENSMUST00000028648.2
Syt13
synaptotagmin XIII
chr2_-_92370968 2.99 ENSMUST00000176774.1
Gyltl1b
glycosyltransferase-like 1B
chr17_-_23684019 2.92 ENSMUST00000085989.5
Cldn9
claudin 9
chr3_+_145292472 2.87 ENSMUST00000029848.4
ENSMUST00000139001.1
Col24a1
collagen, type XXIV, alpha 1
chr13_+_55369732 2.87 ENSMUST00000063771.7
Rgs14
regulator of G-protein signaling 14
chr15_-_79834261 2.80 ENSMUST00000148358.1
Cbx6
chromobox 6
chr15_-_78572754 2.77 ENSMUST00000043214.6
Rac2
RAS-related C3 botulinum substrate 2
chr15_-_79834224 2.72 ENSMUST00000109623.1
ENSMUST00000109625.1
ENSMUST00000023060.6
ENSMUST00000089299.5
Cbx6
Npcd
chromobox 6
neuronal pentraxin chromo domain
chr6_+_34476207 2.70 ENSMUST00000045372.5
ENSMUST00000138668.1
ENSMUST00000139067.1
Bpgm
2,3-bisphosphoglycerate mutase
chr1_+_52008210 2.69 ENSMUST00000027277.5
Stat4
signal transducer and activator of transcription 4
chr18_-_62179948 2.68 ENSMUST00000053640.3
Adrb2
adrenergic receptor, beta 2
chr17_+_48462355 2.68 ENSMUST00000162132.1
Unc5cl
unc-5 homolog C (C. elegans)-like
chr18_+_62180119 2.67 ENSMUST00000067743.1
Gm9949
predicted gene 9949
chr7_+_118712516 2.63 ENSMUST00000106557.1
Ccp110
centriolar coiled coil protein 110
chr5_+_121220191 2.61 ENSMUST00000119892.2
ENSMUST00000042614.6
Gm15800
predicted gene 15800
chr2_-_73453918 2.56 ENSMUST00000102679.1
Wipf1
WAS/WASL interacting protein family, member 1
chr3_-_127499095 2.54 ENSMUST00000182594.1
Ank2
ankyrin 2, brain
chr4_+_129985098 2.43 ENSMUST00000106017.1
ENSMUST00000121049.1
Bai2
brain-specific angiogenesis inhibitor 2
chr9_-_61976563 2.43 ENSMUST00000113990.1
Paqr5
progestin and adipoQ receptor family member V
chr19_-_4615453 2.37 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr11_-_69858723 2.34 ENSMUST00000001626.3
ENSMUST00000108626.1
Tnk1
tyrosine kinase, non-receptor, 1
chr9_+_62838767 2.32 ENSMUST00000034776.6
Cln6
ceroid-lipofuscinosis, neuronal 6
chr8_+_88272403 2.28 ENSMUST00000169037.1
Adcy7
adenylate cyclase 7
chr4_+_94556546 2.25 ENSMUST00000094969.1
Gm10306
predicted gene 10306
chr8_+_70315759 2.24 ENSMUST00000165819.2
ENSMUST00000140239.1
Gdf1
Cers1
growth differentiation factor 1
ceramide synthase 1
chr10_-_61273409 2.24 ENSMUST00000092486.4
Adamts14
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 14
chr16_+_49699198 2.23 ENSMUST00000046777.4
ENSMUST00000142682.1
Ift57
intraflagellar transport 57
chr17_-_47833169 2.20 ENSMUST00000131971.1
ENSMUST00000129360.1
ENSMUST00000113280.1
ENSMUST00000132125.1
Mdfi
MyoD family inhibitor
chr11_+_44518959 2.19 ENSMUST00000019333.3
Rnf145
ring finger protein 145
chr11_+_68692070 2.18 ENSMUST00000108673.1
Myh10
myosin, heavy polypeptide 10, non-muscle
chr17_-_47833256 2.16 ENSMUST00000152455.1
ENSMUST00000035375.7
Mdfi
MyoD family inhibitor
chr16_+_11984581 2.12 ENSMUST00000170672.2
ENSMUST00000023138.7
Shisa9
shisa homolog 9 (Xenopus laevis)
chr3_-_92485886 2.11 ENSMUST00000054599.7
Sprr1a
small proline-rich protein 1A
chr2_+_165595009 2.11 ENSMUST00000088132.6
Eya2
eyes absent 2 homolog (Drosophila)
chr10_-_76961788 2.10 ENSMUST00000001148.4
ENSMUST00000105411.2
Pcbp3
poly(rC) binding protein 3
chr3_-_89418287 2.10 ENSMUST00000029679.3
Cks1b
CDC28 protein kinase 1b
chr13_+_20090538 2.09 ENSMUST00000072519.5
Elmo1
engulfment and cell motility 1
chr10_+_80264942 2.08 ENSMUST00000105362.1
ENSMUST00000105361.3
Dazap1
DAZ associated protein 1
chr8_+_120537423 2.08 ENSMUST00000118136.1
Gse1
genetic suppressor element 1
chrX_+_159255919 2.02 ENSMUST00000112492.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr9_-_21312255 1.97 ENSMUST00000115433.3
ENSMUST00000003397.7
Ap1m2
adaptor protein complex AP-1, mu 2 subunit
chr7_-_79715669 1.97 ENSMUST00000184137.1
ENSMUST00000183846.1
Kif7
kinesin family member 7
chr3_+_108085976 1.96 ENSMUST00000070502.1
Gm12500
predicted gene 12500
chr15_+_54745702 1.96 ENSMUST00000050027.8
Nov
nephroblastoma overexpressed gene
chr2_+_130274437 1.95 ENSMUST00000141872.1
Nop56
NOP56 ribonucleoprotein
chrY_+_90843934 1.91 ENSMUST00000178550.1
Gm21742
predicted gene, 21742
chr11_+_3289880 1.90 ENSMUST00000110043.1
ENSMUST00000094471.3
Patz1
POZ (BTB) and AT hook containing zinc finger 1
chr15_-_98778150 1.89 ENSMUST00000023732.5
Wnt10b
wingless related MMTV integration site 10b
chr5_-_140565060 1.89 ENSMUST00000042993.6
Grifin
galectin-related inter-fiber protein
chr11_+_68691906 1.88 ENSMUST00000102611.3
Myh10
myosin, heavy polypeptide 10, non-muscle
chr2_+_153108468 1.83 ENSMUST00000109799.1
ENSMUST00000003370.7
Hck
hemopoietic cell kinase
chr18_-_24603791 1.82 ENSMUST00000070726.3
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr13_+_20090500 1.80 ENSMUST00000165249.2
Elmo1
engulfment and cell motility 1
chr8_+_94152607 1.79 ENSMUST00000034211.8
Mt3
metallothionein 3
chr1_+_135729147 1.79 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr2_+_25242227 1.77 ENSMUST00000154498.1
Rnf208
ring finger protein 208
chr11_+_77982710 1.76 ENSMUST00000108360.1
ENSMUST00000049167.7
Phf12
PHD finger protein 12
chr13_-_32338565 1.76 ENSMUST00000041859.7
Gmds
GDP-mannose 4, 6-dehydratase
chr7_-_83735503 1.73 ENSMUST00000001792.4
Il16
interleukin 16
chr7_-_126160992 1.73 ENSMUST00000164741.1
Xpo6
exportin 6
chr18_+_65581704 1.71 ENSMUST00000182979.1
Zfp532
zinc finger protein 532
chr17_+_34592248 1.71 ENSMUST00000038149.6
Pbx2
pre B cell leukemia homeobox 2
chr5_-_134614953 1.70 ENSMUST00000036362.6
ENSMUST00000077636.4
Lat2
linker for activation of T cells family, member 2
chr15_-_102231920 1.69 ENSMUST00000001327.3
ENSMUST00000127014.1
Itgb7
integrin beta 7
chr19_-_4615647 1.68 ENSMUST00000113822.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chrX_-_166585679 1.68 ENSMUST00000000412.2
Egfl6
EGF-like-domain, multiple 6
chr15_+_102503722 1.67 ENSMUST00000096145.4
Gm10337
predicted gene 10337
chr15_-_74709535 1.65 ENSMUST00000050234.2
Jrk
jerky
chr6_-_137169678 1.64 ENSMUST00000119610.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr2_+_32876114 1.64 ENSMUST00000028135.8
Fam129b
family with sequence similarity 129, member B
chr1_-_87156127 1.59 ENSMUST00000160810.1
Ecel1
endothelin converting enzyme-like 1
chr3_+_131112785 1.55 ENSMUST00000098611.3
Lef1
lymphoid enhancer binding factor 1
chr4_+_129984833 1.53 ENSMUST00000120204.1
Bai2
brain-specific angiogenesis inhibitor 2
chr14_-_54686926 1.53 ENSMUST00000022793.8
ENSMUST00000111484.2
Acin1
apoptotic chromatin condensation inducer 1
chr11_+_68692097 1.50 ENSMUST00000018887.8
Myh10
myosin, heavy polypeptide 10, non-muscle
chr6_-_91116785 1.48 ENSMUST00000113509.1
ENSMUST00000032179.7
Nup210
nucleoporin 210
chr2_-_38287174 1.47 ENSMUST00000130472.1
Dennd1a
DENN/MADD domain containing 1A
chr4_+_134468320 1.47 ENSMUST00000030636.4
ENSMUST00000127279.1
ENSMUST00000105867.1
Stmn1
stathmin 1
chr8_+_83389846 1.44 ENSMUST00000002259.6
Clgn
calmegin
chr6_+_86849488 1.43 ENSMUST00000089519.6
ENSMUST00000113668.1
Aak1
AP2 associated kinase 1
chr3_-_56183678 1.41 ENSMUST00000029374.6
Nbea
neurobeachin
chr2_+_130274424 1.40 ENSMUST00000103198.4
Nop56
NOP56 ribonucleoprotein
chr4_+_140986873 1.38 ENSMUST00000168047.1
ENSMUST00000037055.7
ENSMUST00000127833.2
Atp13a2
ATPase type 13A2
chr8_+_83389878 1.37 ENSMUST00000109831.2
Clgn
calmegin
chrX_+_9272756 1.36 ENSMUST00000015486.6
Xk
Kell blood group precursor (McLeod phenotype) homolog
chr17_-_36867187 1.36 ENSMUST00000025329.6
ENSMUST00000174195.1
Trim15
tripartite motif-containing 15
chr15_+_32244801 1.36 ENSMUST00000067458.6
Sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr11_+_115974709 1.31 ENSMUST00000021107.7
ENSMUST00000106461.1
ENSMUST00000169928.1
Itgb4
integrin beta 4
chr9_+_32696005 1.29 ENSMUST00000034534.6
ENSMUST00000050797.7
ENSMUST00000184887.1
Ets1
E26 avian leukemia oncogene 1, 5' domain
chr15_-_79141197 1.29 ENSMUST00000169604.1
1700088E04Rik
RIKEN cDNA 1700088E04 gene
chr14_-_54686605 1.28 ENSMUST00000147714.1
Acin1
apoptotic chromatin condensation inducer 1
chr11_-_69858687 1.28 ENSMUST00000125571.1
Tnk1
tyrosine kinase, non-receptor, 1
chr15_+_103503261 1.28 ENSMUST00000023132.3
Pde1b
phosphodiesterase 1B, Ca2+-calmodulin dependent
chr1_+_166130467 1.24 ENSMUST00000166860.1
Gpa33
glycoprotein A33 (transmembrane)
chr15_-_79834323 1.23 ENSMUST00000177316.2
ENSMUST00000175858.2
Nptxr
neuronal pentraxin receptor
chr11_+_62820469 1.23 ENSMUST00000108703.1
Trim16
tripartite motif-containing 16
chr10_+_80265035 1.22 ENSMUST00000092305.5
Dazap1
DAZ associated protein 1
chr8_+_83900706 1.18 ENSMUST00000045393.8
ENSMUST00000132500.1
ENSMUST00000152978.1
Lphn1
latrophilin 1
chr1_+_166130238 1.18 ENSMUST00000060833.7
ENSMUST00000166159.1
Gpa33
glycoprotein A33 (transmembrane)
chrX_+_159255782 1.16 ENSMUST00000126686.1
ENSMUST00000033671.6
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr5_-_39644597 1.12 ENSMUST00000152057.1
Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr7_-_46179929 1.09 ENSMUST00000033123.6
Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr2_-_162661075 1.08 ENSMUST00000109442.1
ENSMUST00000109445.2
ENSMUST00000109443.1
ENSMUST00000109441.1
Ptprt
protein tyrosine phosphatase, receptor type, T
chr9_+_106170918 1.07 ENSMUST00000020490.5
Wdr82
WD repeat domain containing 82
chr15_-_32244632 1.05 ENSMUST00000181536.1
0610007N19Rik
RIKEN cDNA 0610007N19
chr11_+_68432112 1.05 ENSMUST00000021283.7
Pik3r5
phosphoinositide-3-kinase, regulatory subunit 5, p101
chr11_-_94242701 1.04 ENSMUST00000061469.3
Wfikkn2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr15_-_13173607 1.04 ENSMUST00000036439.4
Cdh6
cadherin 6
chr18_+_34220890 1.03 ENSMUST00000171187.1
Apc
adenomatosis polyposis coli
chr17_-_24073479 1.03 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5
chr2_-_164404606 1.02 ENSMUST00000109359.1
ENSMUST00000109358.1
ENSMUST00000103103.3
Matn4
matrilin 4
chr15_+_59374198 1.01 ENSMUST00000079703.3
ENSMUST00000168722.1
Nsmce2
non-SMC element 2 homolog (MMS21, S. cerevisiae)
chr6_-_137169710 1.00 ENSMUST00000117919.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr1_-_153186447 0.98 ENSMUST00000027753.6
Lamc2
laminin, gamma 2
chr14_-_52237791 0.97 ENSMUST00000149975.1
Chd8
chromodomain helicase DNA binding protein 8
chr5_+_100518309 0.96 ENSMUST00000045993.8
ENSMUST00000151414.1
Cops4
COP9 (constitutive photomorphogenic) homolog, subunit 4 (Arabidopsis thaliana)
chr15_-_79687776 0.96 ENSMUST00000023061.5
Josd1
Josephin domain containing 1
chr5_-_33274966 0.96 ENSMUST00000079746.6
Ctbp1
C-terminal binding protein 1
chr2_+_118926496 0.92 ENSMUST00000099546.4
ENSMUST00000110837.1
Chst14
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr15_-_85578070 0.91 ENSMUST00000109424.2
Wnt7b
wingless-related MMTV integration site 7B
chr9_-_44735189 0.91 ENSMUST00000034611.8
Phldb1
pleckstrin homology-like domain, family B, member 1
chr2_+_28513105 0.90 ENSMUST00000135803.1
Ralgds
ral guanine nucleotide dissociation stimulator
chr11_+_115974930 0.90 ENSMUST00000106460.2
Itgb4
integrin beta 4
chr11_-_102319093 0.89 ENSMUST00000174302.1
ENSMUST00000178839.1
ENSMUST00000006754.7
Ubtf
upstream binding transcription factor, RNA polymerase I
chr5_-_139130159 0.88 ENSMUST00000129851.1
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr17_+_86963279 0.87 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr4_+_116221689 0.86 ENSMUST00000106490.2
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr5_+_147430407 0.84 ENSMUST00000176600.1
Pan3
PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr9_-_110654161 0.84 ENSMUST00000133191.1
ENSMUST00000167320.1
Nbeal2
neurobeachin-like 2
chr17_-_12769605 0.81 ENSMUST00000024599.7
Igf2r
insulin-like growth factor 2 receptor
chr5_+_115429944 0.79 ENSMUST00000067168.5
Msi1
musashi RNA-binding protein 1
chr13_-_38658991 0.78 ENSMUST00000001757.7
Eef1e1
eukaryotic translation elongation factor 1 epsilon 1
chr15_+_60822947 0.78 ENSMUST00000180730.1
9930014A18Rik
RIKEN cDNA 9930014A18 gene
chrX_-_74373260 0.77 ENSMUST00000073067.4
ENSMUST00000037967.5
Slc10a3
solute carrier family 10 (sodium/bile acid cotransporter family), member 3
chr1_-_143702832 0.77 ENSMUST00000018337.7
Cdc73
cell division cycle 73, Paf1/RNA polymerase II complex component
chr3_-_108085346 0.77 ENSMUST00000078912.5
Ampd2
adenosine monophosphate deaminase 2
chr5_-_39644634 0.76 ENSMUST00000053116.6
Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr11_-_116110211 0.76 ENSMUST00000106441.1
ENSMUST00000021120.5
Trim47
tripartite motif-containing 47
chr17_-_35979679 0.76 ENSMUST00000173724.1
ENSMUST00000172900.1
ENSMUST00000174849.1
Prr3
proline-rich polypeptide 3
chr10_-_80844025 0.75 ENSMUST00000053986.7
Lingo3
leucine rich repeat and Ig domain containing 3
chr12_-_24493656 0.73 ENSMUST00000073088.2
Gm16372
predicted pseudogene 16372
chr2_+_28192971 0.72 ENSMUST00000113920.1
Olfm1
olfactomedin 1
chr4_+_156013835 0.70 ENSMUST00000030952.5
Tnfrsf4
tumor necrosis factor receptor superfamily, member 4
chr8_+_82863351 0.69 ENSMUST00000078525.5
Rnf150
ring finger protein 150
chr2_-_119271202 0.69 ENSMUST00000037360.7
Rhov
ras homolog gene family, member V
chr14_-_52237572 0.69 ENSMUST00000089752.4
Chd8
chromodomain helicase DNA binding protein 8
chr17_-_33824346 0.67 ENSMUST00000173879.1
ENSMUST00000166693.2
ENSMUST00000173019.1
ENSMUST00000087342.6
ENSMUST00000173844.1
Rps28
ribosomal protein S28
chr5_-_34288318 0.66 ENSMUST00000094868.3
Zfyve28
zinc finger, FYVE domain containing 28
chr15_-_79254737 0.65 ENSMUST00000039752.3
Slc16a8
solute carrier family 16 (monocarboxylic acid transporters), member 8
chr7_-_30914327 0.63 ENSMUST00000040548.7
Mag
myelin-associated glycoprotein
chr17_+_35194502 0.61 ENSMUST00000173600.1
Ltb
lymphotoxin B
chr1_-_9700209 0.61 ENSMUST00000088658.4
Mybl1
myeloblastosis oncogene-like 1
chr3_-_88548249 0.61 ENSMUST00000131775.1
ENSMUST00000008745.6
Rab25
RAB25, member RAS oncogene family

Network of associatons between targets according to the STRING database.

First level regulatory network of Hmx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 13.2 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
3.5 10.4 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
2.7 8.1 GO:0051714 regulation of cytolysis in other organism(GO:0051710) positive regulation of cytolysis in other organism(GO:0051714)
2.2 6.5 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
1.9 5.6 GO:0070650 actin filament bundle distribution(GO:0070650)
1.8 16.5 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
1.6 4.8 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
1.0 4.2 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.9 3.7 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) positive regulation of endocytic recycling(GO:2001137)
0.9 4.5 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.9 1.8 GO:0097212 lysosomal membrane organization(GO:0097212)
0.7 2.2 GO:0071492 cellular response to UV-A(GO:0071492) response to dithiothreitol(GO:0072720)
0.7 3.6 GO:0006177 GMP biosynthetic process(GO:0006177)
0.7 3.4 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.7 10.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.7 2.7 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.7 2.6 GO:0032053 ciliary basal body organization(GO:0032053)
0.7 2.0 GO:0071603 negative regulation of SMAD protein import into nucleus(GO:0060392) endothelial cell-cell adhesion(GO:0071603) negative regulation of sensory perception of pain(GO:1904057) bone regeneration(GO:1990523)
0.6 3.8 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.5 2.7 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.5 4.8 GO:0070314 G1 to G0 transition(GO:0070314)
0.5 2.4 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.5 1.9 GO:0051885 positive regulation of anagen(GO:0051885)
0.4 3.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.4 12.2 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.4 1.6 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.4 5.0 GO:0070995 NADPH oxidation(GO:0070995)
0.4 1.1 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.4 2.8 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.3 3.5 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.3 1.4 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.3 1.0 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.3 6.3 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.3 1.0 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.3 0.9 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.3 0.9 GO:0061642 chemoattraction of axon(GO:0061642)
0.3 2.5 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.3 1.4 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.3 2.1 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.3 2.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.3 2.9 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.3 1.3 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.2 1.2 GO:0023041 neuronal signal transduction(GO:0023041)
0.2 3.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.2 3.9 GO:0006968 cellular defense response(GO:0006968)
0.2 1.4 GO:0031133 regulation of axon diameter(GO:0031133)
0.2 1.4 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.2 1.5 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.2 0.8 GO:0070889 platelet alpha granule organization(GO:0070889)
0.2 2.2 GO:0035878 nail development(GO:0035878)
0.2 1.8 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.2 2.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 4.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.2 1.3 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.2 0.8 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.2 0.3 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.2 2.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 1.8 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 1.7 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 7.0 GO:0010883 regulation of lipid storage(GO:0010883)
0.1 0.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 2.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 1.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 1.0 GO:0044337 canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337) positive regulation of protein localization to centrosome(GO:1904781)
0.1 3.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.6 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 8.3 GO:0048747 muscle fiber development(GO:0048747)
0.1 1.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 5.1 GO:0030199 collagen fibril organization(GO:0030199)
0.1 2.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.0 GO:0032264 IMP salvage(GO:0032264)
0.1 1.9 GO:0070831 basement membrane assembly(GO:0070831)
0.1 1.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 0.9 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.1 0.8 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 3.3 GO:0000154 rRNA modification(GO:0000154)
0.1 2.2 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.3 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 1.6 GO:0032274 gonadotropin secretion(GO:0032274)
0.1 3.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 2.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 0.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.3 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 5.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 2.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 1.1 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 2.1 GO:0031424 keratinization(GO:0031424)
0.1 1.0 GO:0000338 protein deneddylation(GO:0000338)
0.1 2.0 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 3.4 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.1 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.6 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.1 0.8 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.1 0.6 GO:0031268 pseudopodium organization(GO:0031268)
0.0 1.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.9 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 1.7 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 1.6 GO:0003016 respiratory system process(GO:0003016)
0.0 0.2 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.5 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 1.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 1.0 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.4 GO:0071044 histone mRNA catabolic process(GO:0071044) RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 3.9 GO:0043627 response to estrogen(GO:0043627)
0.0 1.7 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.9 GO:1903077 cortical actin cytoskeleton organization(GO:0030866) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 3.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.1 GO:1905034 regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035)
0.0 2.4 GO:0048477 oogenesis(GO:0048477)
0.0 0.8 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.1 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.5 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 1.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 1.0 GO:0048678 response to axon injury(GO:0048678)
0.0 1.1 GO:0070527 platelet aggregation(GO:0070527)
0.0 4.2 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.1 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.1 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.4 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 2.6 GO:0030217 T cell differentiation(GO:0030217)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.5 GO:0031523 Myb complex(GO:0031523)
0.9 5.6 GO:0097513 myosin II filament(GO:0097513)
0.8 3.0 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.6 12.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.5 3.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.4 10.8 GO:0005859 muscle myosin complex(GO:0005859)
0.4 3.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.3 1.0 GO:0005607 laminin-2 complex(GO:0005607)
0.3 2.8 GO:0061574 ASAP complex(GO:0061574)
0.3 4.8 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.3 4.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.3 0.8 GO:0031251 PAN complex(GO:0031251)
0.3 1.4 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.3 1.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.3 1.0 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.3 4.8 GO:0031045 dense core granule(GO:0031045)
0.3 5.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 3.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 2.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 14.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 1.0 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.2 1.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.0 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.4 GO:0044299 C-fiber(GO:0044299)
0.1 1.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 3.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.7 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 1.4 GO:0071439 clathrin complex(GO:0071439)
0.1 2.2 GO:0044292 dendrite terminus(GO:0044292)
0.1 7.1 GO:0005871 kinesin complex(GO:0005871)
0.1 2.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 4.1 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.8 GO:0016580 Sin3 complex(GO:0016580)
0.1 2.5 GO:0031430 M band(GO:0031430)
0.1 0.6 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 0.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 5.5 GO:0031519 PcG protein complex(GO:0031519)
0.1 5.1 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.9 GO:0045180 basal cortex(GO:0045180)
0.1 2.1 GO:0001533 cornified envelope(GO:0001533)
0.1 5.0 GO:0016528 sarcoplasm(GO:0016528)
0.1 3.5 GO:0005844 polysome(GO:0005844)
0.1 4.9 GO:0005643 nuclear pore(GO:0005643)
0.1 2.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.7 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 1.7 GO:0008305 integrin complex(GO:0008305)
0.0 3.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.8 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 0.8 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 3.8 GO:0005581 collagen trimer(GO:0005581)
0.0 5.6 GO:0005884 actin filament(GO:0005884)
0.0 1.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 2.6 GO:0005814 centriole(GO:0005814)
0.0 2.9 GO:0000922 spindle pole(GO:0000922)
0.0 3.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 8.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 18.4 GO:0005615 extracellular space(GO:0005615)
0.0 0.3 GO:0072686 mitotic spindle(GO:0072686)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 8.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
1.3 6.5 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
1.2 3.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
1.1 3.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.9 3.6 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.9 2.7 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.7 2.7 GO:0004939 beta-adrenergic receptor activity(GO:0004939) bradykinin receptor binding(GO:0031711)
0.6 10.8 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.5 2.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.5 3.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.5 13.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.5 1.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.4 2.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.4 2.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.3 3.7 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.3 2.2 GO:0038132 neuregulin binding(GO:0038132)
0.3 1.2 GO:0001847 opsonin receptor activity(GO:0001847)
0.3 5.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.3 1.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 4.2 GO:0002162 dystroglycan binding(GO:0002162)
0.2 0.9 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 10.0 GO:0070412 R-SMAD binding(GO:0070412)
0.2 2.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 8.0 GO:0030506 ankyrin binding(GO:0030506)
0.2 1.6 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 1.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 3.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 5.0 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.2 4.4 GO:0019956 chemokine binding(GO:0019956)
0.2 0.9 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.2 1.3 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 0.9 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 5.6 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.2 1.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.2 1.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 3.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 3.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 2.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 1.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 2.9 GO:0001618 virus receptor activity(GO:0001618)
0.1 2.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 1.0 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 7.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 2.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.3 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.1 7.1 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 18.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 5.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 3.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 3.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.9 GO:0005522 profilin binding(GO:0005522)
0.1 0.3 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 2.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.4 GO:0051880 G-quadruplex RNA binding(GO:0002151) G-quadruplex DNA binding(GO:0051880)
0.1 5.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.6 GO:0033691 sialic acid binding(GO:0033691)
0.1 6.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 3.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.5 GO:0043426 MRF binding(GO:0043426)
0.1 3.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.9 GO:0005109 frizzled binding(GO:0005109)
0.0 1.0 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 1.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.8 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 1.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 5.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.1 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 16.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3 15.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 3.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 3.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 13.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 8.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 2.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.6 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 1.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 2.3 PID IL27 PATHWAY IL27-mediated signaling events
0.1 3.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 3.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.4 PID ARF6 PATHWAY Arf6 signaling events
0.1 4.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 2.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 2.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 3.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 4.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 1.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 4.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.4 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 3.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 16.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 13.2 REACTOME KINESINS Genes involved in Kinesins
0.3 12.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.3 8.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 7.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 3.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.2 7.7 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.2 3.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 2.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 2.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 3.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 5.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 3.8 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 3.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 8.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 5.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.0 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 2.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.0 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 2.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 2.8 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 2.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 2.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.7 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 1.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.2 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.9 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 2.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex