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GSE58827: Dynamics of the Mouse Liver

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Results for Hoxa11_Hoxc12

Z-value: 0.69

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Transcription factors associated with Hoxa11_Hoxc12

Gene Symbol Gene ID Gene Info
Hoxa11
ENSMUSG00000038210.9 homeobox A11
Hoxc12
ENSMUSG00000050328.2 homeobox C12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxa11mm10_v2_chr6_-_52246214_52246214-0.009.9e-01Click!

Activity profile of Hoxa11_Hoxc12 motif

Sorted Z-values of Hoxa11_Hoxc12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_39287074 4.54 ENSMUST00000003137.8
Cyp2c29
cytochrome P450, family 2, subfamily c, polypeptide 29
chr4_-_62150810 1.99 ENSMUST00000077719.3
Mup21
major urinary protein 21
chr3_+_81996922 1.79 ENSMUST00000029641.3
Asic5
acid-sensing (proton-gated) ion channel family member 5
chr2_+_23068168 1.34 ENSMUST00000028121.7
ENSMUST00000114523.2
ENSMUST00000144088.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr17_+_22361453 1.33 ENSMUST00000149699.1
ENSMUST00000088765.2
ENSMUST00000072477.4
ENSMUST00000121315.1
Zfp758
zinc finger protein 758
chr16_-_16600533 1.28 ENSMUST00000159542.1
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr11_-_30986326 1.25 ENSMUST00000020553.4
ENSMUST00000101394.4
Chac2
ChaC, cation transport regulator 2
chr17_-_21845759 1.15 ENSMUST00000084141.4
Zfp820
zinc finger protein 820
chr18_-_38209762 1.09 ENSMUST00000057185.6
Pcdh1
protocadherin 1
chr18_-_10706688 1.04 ENSMUST00000002549.7
ENSMUST00000117726.1
ENSMUST00000117828.1
Abhd3
abhydrolase domain containing 3
chr16_-_57231434 1.00 ENSMUST00000023431.6
Tbc1d23
TBC1 domain family, member 23
chr12_+_78226627 1.00 ENSMUST00000110388.2
ENSMUST00000052472.4
Gphn
gephyrin
chr5_-_123666682 0.95 ENSMUST00000149410.1
Clip1
CAP-GLY domain containing linker protein 1
chr11_-_62457772 0.91 ENSMUST00000127471.2
Ncor1
nuclear receptor co-repressor 1
chr19_+_5406815 0.91 ENSMUST00000174412.1
ENSMUST00000153017.2
4930481A15Rik
RIKEN cDNA 4930481A15 gene
chr2_-_180824596 0.89 ENSMUST00000148700.1
Gm14340
predicted gene 14340
chr6_+_149141638 0.88 ENSMUST00000166416.1
ENSMUST00000111551.1
Mettl20
methyltransferase like 20
chr7_-_135528645 0.88 ENSMUST00000053716.7
Clrn3
clarin 3
chr2_+_131133497 0.87 ENSMUST00000110225.1
Gm11037
predicted gene 11037
chr7_-_73537621 0.86 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr8_-_69373914 0.82 ENSMUST00000095282.1
Gm10311
predicted gene 10311
chr9_+_3404058 0.81 ENSMUST00000027027.5
Cwf19l2
CWF19-like 2, cell cycle control (S. pombe)
chr14_+_49172202 0.80 ENSMUST00000153488.1
Naa30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr1_-_182409020 0.79 ENSMUST00000097444.1
Gm10517
predicted gene 10517
chr6_+_149141513 0.78 ENSMUST00000047531.9
ENSMUST00000179873.1
ENSMUST00000111548.1
ENSMUST00000111547.1
ENSMUST00000134306.1
Mettl20
methyltransferase like 20
chr8_+_45069374 0.76 ENSMUST00000130141.1
Mtnr1a
melatonin receptor 1A
chr9_-_50659780 0.75 ENSMUST00000034567.3
Dlat
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr5_+_119625939 0.75 ENSMUST00000156235.1
Gm16063
predicted gene 16063
chr1_+_88087802 0.71 ENSMUST00000113139.1
Ugt1a8
UDP glucuronosyltransferase 1 family, polypeptide A8
chr7_-_120145286 0.69 ENSMUST00000033207.4
Zp2
zona pellucida glycoprotein 2
chr9_+_37613806 0.69 ENSMUST00000002007.3
Siae
sialic acid acetylesterase
chr5_+_32611171 0.68 ENSMUST00000072311.6
ENSMUST00000168707.2
Yes1
Yamaguchi sarcoma viral (v-yes) oncogene homolog 1
chr13_+_65512678 0.68 ENSMUST00000081471.2
Gm10139
predicted gene 10139
chrX_-_165004829 0.65 ENSMUST00000114890.2
Gm17604
predicted gene, 17604
chr1_-_136960427 0.65 ENSMUST00000027649.7
Nr5a2
nuclear receptor subfamily 5, group A, member 2
chr9_+_75441518 0.64 ENSMUST00000048937.4
Leo1
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr18_+_37655891 0.64 ENSMUST00000097608.2
3222401L13Rik
RIKEN cDNA 3222401L13 gene
chr1_+_178529113 0.62 ENSMUST00000161017.1
Kif26b
kinesin family member 26B
chr6_+_29471437 0.62 ENSMUST00000171317.1
Gm9047
predicted gene 9047
chr1_-_173227229 0.59 ENSMUST00000049706.5
Fcer1a
Fc receptor, IgE, high affinity I, alpha polypeptide
chr14_+_27622433 0.59 ENSMUST00000090302.5
Erc2
ELKS/RAB6-interacting/CAST family member 2
chr11_-_72267141 0.57 ENSMUST00000137701.1
Slc13a5
solute carrier family 13 (sodium-dependent citrate transporter), member 5
chr13_-_12464925 0.56 ENSMUST00000124888.1
Lgals8
lectin, galactose binding, soluble 8
chr17_+_75465538 0.56 ENSMUST00000095204.4
Rasgrp3
RAS, guanyl releasing protein 3
chr8_-_69625503 0.54 ENSMUST00000121886.1
Zfp868
zinc finger protein 868
chr11_-_23895208 0.54 ENSMUST00000102863.2
ENSMUST00000020513.3
Papolg
poly(A) polymerase gamma
chr7_-_119895446 0.52 ENSMUST00000098080.2
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr19_+_4097392 0.50 ENSMUST00000174514.1
ENSMUST00000174149.1
Cdk2ap2
CDK2-associated protein 2
chr11_-_115627948 0.48 ENSMUST00000154623.1
ENSMUST00000106503.3
ENSMUST00000141614.1
Slc25a19
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr7_-_141435327 0.48 ENSMUST00000138865.1
Slc25a22
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr14_-_34503323 0.47 ENSMUST00000171343.1
Bmpr1a
bone morphogenetic protein receptor, type 1A
chr6_+_91878034 0.47 ENSMUST00000037783.5
Ccdc174
coiled-coil domain containing 174
chr19_+_29945782 0.47 ENSMUST00000025724.8
Il33
interleukin 33
chr17_+_8182247 0.46 ENSMUST00000161898.1
Fgfr1op
Fgfr1 oncogene partner
chr3_+_32436376 0.45 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr3_+_69721985 0.44 ENSMUST00000029358.8
Nmd3
NMD3 homolog (S. cerevisiae)
chr4_+_136143497 0.44 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr13_+_98263242 0.43 ENSMUST00000022164.8
ENSMUST00000150352.1
Ankra2
ankyrin repeat, family A (RFXANK-like), 2
chr6_+_108213086 0.43 ENSMUST00000032192.6
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr7_-_141434532 0.42 ENSMUST00000133021.1
ENSMUST00000106007.3
ENSMUST00000150026.1
ENSMUST00000133206.2
Slc25a22
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr1_+_88070765 0.42 ENSMUST00000073772.4
Ugt1a9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr9_-_106247730 0.40 ENSMUST00000112524.2
ENSMUST00000074082.6
Alas1
aminolevulinic acid synthase 1
chr9_-_55919605 0.40 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr8_+_11840474 0.38 ENSMUST00000033909.7
Tex29
testis expressed 29
chr13_+_47193942 0.37 ENSMUST00000110111.2
Rnf144b
ring finger protein 144B
chrX_+_20364481 0.37 ENSMUST00000033372.6
ENSMUST00000115391.1
ENSMUST00000115387.1
Rp2h
retinitis pigmentosa 2 homolog (human)
chr2_-_120970706 0.37 ENSMUST00000028728.5
Ubr1
ubiquitin protein ligase E3 component n-recognin 1
chr11_-_5542177 0.36 ENSMUST00000020776.4
Ccdc117
coiled-coil domain containing 117
chr3_+_66219909 0.36 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr1_-_136131171 0.35 ENSMUST00000146091.3
ENSMUST00000165464.1
ENSMUST00000166747.1
ENSMUST00000134998.1
Gm15850
predicted gene 15850
chr13_+_98263187 0.35 ENSMUST00000091356.3
ENSMUST00000123924.1
Ankra2
ankyrin repeat, family A (RFXANK-like), 2
chr3_+_132634725 0.35 ENSMUST00000163241.1
Gm5549
predicted gene 5549
chr1_+_182409162 0.34 ENSMUST00000117245.1
Trp53bp2
transformation related protein 53 binding protein 2
chr7_-_41448641 0.34 ENSMUST00000165029.1
Vmn2r57
vomeronasal 2, receptor 57
chr8_+_33653238 0.33 ENSMUST00000033992.8
Gsr
glutathione reductase
chr13_+_98263105 0.33 ENSMUST00000150916.1
Ankra2
ankyrin repeat, family A (RFXANK-like), 2
chr6_+_96115249 0.33 ENSMUST00000075080.5
Fam19a1
family with sequence similarity 19, member A1
chr11_+_60479915 0.33 ENSMUST00000126522.1
Myo15
myosin XV
chr11_-_115628125 0.32 ENSMUST00000155709.1
ENSMUST00000021089.4
Slc25a19
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr4_-_138367966 0.32 ENSMUST00000030535.3
Cda
cytidine deaminase
chr2_-_26516620 0.31 ENSMUST00000132820.1
Notch1
notch 1
chr5_-_20951769 0.30 ENSMUST00000036489.5
Rsbn1l
round spermatid basic protein 1-like
chr14_+_54883377 0.30 ENSMUST00000022806.3
ENSMUST00000172844.1
ENSMUST00000133397.2
ENSMUST00000134077.1
Bcl2l2
Gm20521
BCL2-like 2
predicted gene 20521
chr16_-_23225334 0.30 ENSMUST00000055369.4
BC106179
cDNA sequence BC106179
chr7_-_140507318 0.29 ENSMUST00000064392.6
Olfr536
olfactory receptor 536
chr6_+_40471352 0.28 ENSMUST00000114779.2
ENSMUST00000031971.6
ENSMUST00000121360.1
ENSMUST00000117411.1
ENSMUST00000117830.1
Ssbp1
single-stranded DNA binding protein 1
chr16_-_56024628 0.28 ENSMUST00000119981.1
ENSMUST00000096021.3
Pcnp
PEST proteolytic signal containing nuclear protein
chr11_-_115628260 0.28 ENSMUST00000178003.1
Slc25a19
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr3_-_142881942 0.28 ENSMUST00000043812.8
Pkn2
protein kinase N2
chr2_+_166805506 0.27 ENSMUST00000099078.3
Arfgef2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr5_-_38502079 0.27 ENSMUST00000147664.1
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr18_+_69346143 0.27 ENSMUST00000114980.1
Tcf4
transcription factor 4
chr6_-_55681257 0.26 ENSMUST00000044767.8
Neurod6
neurogenic differentiation 6
chr12_-_20900867 0.26 ENSMUST00000079237.5
Zfp125
zinc finger protein 125
chr19_-_7483212 0.26 ENSMUST00000088169.5
Rtn3
reticulon 3
chr3_-_88458876 0.25 ENSMUST00000147200.1
ENSMUST00000169222.1
Sema4a
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr9_+_53771499 0.25 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr1_+_106980979 0.25 ENSMUST00000027564.1
Serpinb13
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13
chr18_-_46280820 0.24 ENSMUST00000025354.3
Pggt1b
protein geranylgeranyltransferase type I, beta subunit
chr12_+_59066908 0.24 ENSMUST00000021381.4
Pnn
pinin
chr1_+_58646608 0.24 ENSMUST00000081455.4
Gm10068
predicted gene 10068
chr9_-_71168657 0.24 ENSMUST00000113570.1
Aqp9
aquaporin 9
chr17_-_13761441 0.23 ENSMUST00000127032.1
Tcte2
t-complex-associated testis expressed 2
chr13_-_35027077 0.23 ENSMUST00000170538.1
ENSMUST00000163280.1
Eci2
enoyl-Coenzyme A delta isomerase 2
chr13_-_99344652 0.21 ENSMUST00000022153.6
Ptcd2
pentatricopeptide repeat domain 2
chr3_-_144849301 0.21 ENSMUST00000159989.1
Clca4
chloride channel calcium activated 4
chr18_+_36744656 0.21 ENSMUST00000007042.5
Ik
IK cytokine
chr16_+_75592844 0.21 ENSMUST00000114249.1
ENSMUST00000046378.7
ENSMUST00000114253.1
Rbm11
RNA binding motif protein 11
chr7_-_46795881 0.20 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr15_-_100424092 0.20 ENSMUST00000154676.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr11_-_102697710 0.19 ENSMUST00000164506.2
ENSMUST00000092569.6
Ccdc43
coiled-coil domain containing 43
chr1_+_161395409 0.19 ENSMUST00000028024.4
Tnfsf4
tumor necrosis factor (ligand) superfamily, member 4
chr6_+_42286709 0.19 ENSMUST00000163936.1
Clcn1
chloride channel 1
chrX_+_73064787 0.19 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chr17_+_8283762 0.18 ENSMUST00000155364.1
ENSMUST00000046754.8
ENSMUST00000124023.1
Mpc1
mitochondrial pyruvate carrier 1
chr5_-_143138200 0.18 ENSMUST00000164536.2
Olfr718-ps1
olfactory receptor 718, pseudogene 1
chrX_-_7319291 0.18 ENSMUST00000128319.1
Clcn5
chloride channel 5
chr3_-_88459047 0.18 ENSMUST00000165898.1
ENSMUST00000127436.1
Sema4a
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr16_-_45408955 0.17 ENSMUST00000163230.1
Cd200
CD200 antigen
chr6_+_42286676 0.17 ENSMUST00000031894.6
Clcn1
chloride channel 1
chr10_-_120979327 0.17 ENSMUST00000119944.1
ENSMUST00000119093.1
Lemd3
LEM domain containing 3
chr3_+_79885930 0.17 ENSMUST00000029567.8
Fam198b
family with sequence similarity 198, member B
chr11_+_55213783 0.17 ENSMUST00000108867.1
Slc36a1
solute carrier family 36 (proton/amino acid symporter), member 1
chr7_+_126649297 0.16 ENSMUST00000032956.8
Ccdc101
coiled-coil domain containing 101
chr5_+_3543812 0.16 ENSMUST00000115527.3
Fam133b
family with sequence similarity 133, member B
chr12_-_23780265 0.15 ENSMUST00000072014.4
Gm10330
predicted gene 10330
chr13_+_58281183 0.15 ENSMUST00000180882.1
ENSMUST00000180452.1
Gm26555
predicted gene, 26555
chr3_+_89177463 0.14 ENSMUST00000029684.8
ENSMUST00000120697.1
ENSMUST00000098941.4
Scamp3
secretory carrier membrane protein 3
chr11_-_102407315 0.14 ENSMUST00000149777.1
ENSMUST00000154001.1
Slc25a39
solute carrier family 25, member 39
chr6_-_87809757 0.13 ENSMUST00000032134.7
Rab43
RAB43, member RAS oncogene family
chr7_+_140247267 0.13 ENSMUST00000059882.6
5830411N06Rik
RIKEN cDNA 5830411N06 gene
chr11_+_77216180 0.12 ENSMUST00000037912.5
ENSMUST00000156488.1
Ssh2
slingshot homolog 2 (Drosophila)
chr3_+_145576196 0.12 ENSMUST00000098534.4
Znhit6
zinc finger, HIT type 6
chr7_-_126649556 0.12 ENSMUST00000084587.1
2510046G10Rik
RIKEN cDNA 2510046G10 gene
chr4_+_39450268 0.12 ENSMUST00000029955.4
1700009N14Rik
RIKEN cDNA 1700009N14 gene
chr3_+_126597299 0.11 ENSMUST00000106400.2
ENSMUST00000106401.1
Camk2d
calcium/calmodulin-dependent protein kinase II, delta
chr1_+_72307413 0.11 ENSMUST00000027379.8
Xrcc5
X-ray repair complementing defective repair in Chinese hamster cells 5
chr9_+_40873981 0.11 ENSMUST00000067375.3
Bsx
brain specific homeobox
chr2_-_147085445 0.11 ENSMUST00000067020.2
Nkx2-4
NK2 homeobox 4
chr16_-_74411776 0.11 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr7_+_43634718 0.10 ENSMUST00000032663.8
Ceacam18
carcinoembryonic antigen-related cell adhesion molecule 18
chr13_-_66852017 0.10 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr7_-_46795661 0.09 ENSMUST00000123725.1
Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr2_+_74711911 0.09 ENSMUST00000111983.2
Hoxd3
homeobox D3
chr4_+_108328136 0.09 ENSMUST00000131656.1
Selrc1
Sel1 repeat containing 1
chr4_+_109235262 0.08 ENSMUST00000106631.2
Calr4
calreticulin 4
chr10_-_67912620 0.08 ENSMUST00000064656.7
Zfp365
zinc finger protein 365
chrX_+_133908441 0.08 ENSMUST00000113304.1
Srpx2
sushi-repeat-containing protein, X-linked 2
chr9_-_14782964 0.08 ENSMUST00000034406.3
Ankrd49
ankyrin repeat domain 49
chr17_+_19362135 0.08 ENSMUST00000176107.1
Vmn2r99
vomeronasal 2, receptor 99
chr3_+_126597415 0.07 ENSMUST00000066452.7
ENSMUST00000171289.1
ENSMUST00000106399.1
Camk2d
calcium/calmodulin-dependent protein kinase II, delta
chr4_+_102741287 0.07 ENSMUST00000097948.2
Sgip1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr6_+_40325471 0.07 ENSMUST00000031977.8
Agk
acylglycerol kinase
chr11_-_4441082 0.06 ENSMUST00000109949.1
ENSMUST00000130174.1
Hormad2
HORMA domain containing 2
chr9_-_110946158 0.06 ENSMUST00000035075.8
Tdgf1
teratocarcinoma-derived growth factor 1
chr12_-_27160311 0.05 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866
predicted gene 9866
chr13_-_19732929 0.05 ENSMUST00000151029.1
A530099J19Rik
RIKEN cDNA A530099J19 gene
chr11_+_59306920 0.05 ENSMUST00000000128.3
ENSMUST00000108783.3
Wnt9a
wingless-type MMTV integration site 9A
chr8_+_40307458 0.05 ENSMUST00000068999.7
Micu3
mitochondrial calcium uptake family, member 3
chr18_-_43393346 0.04 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr8_+_105225145 0.04 ENSMUST00000034361.3
D230025D16Rik
RIKEN cDNA D230025D16 gene
chr7_+_125318334 0.04 ENSMUST00000060220.1
4930533L02Rik
RIKEN cDNA 4930533L02 gene
chr16_+_87354185 0.04 ENSMUST00000054442.4
ENSMUST00000118310.1
ENSMUST00000120284.1
ENSMUST00000118115.1
N6amt1
N-6 adenine-specific DNA methyltransferase 1 (putative)
chr17_-_6477102 0.03 ENSMUST00000167717.2
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr15_+_100423193 0.03 ENSMUST00000148928.1
Gm5475
predicted gene 5475
chr12_-_27160498 0.03 ENSMUST00000182592.1
Gm9866
predicted gene 9866
chr5_+_73651376 0.02 ENSMUST00000071077.7
ENSMUST00000178631.1
ENSMUST00000041422.8
Spata18
spermatogenesis associated 18
chr11_-_65159890 0.01 ENSMUST00000020855.3
ENSMUST00000108696.1
1700086D15Rik
RIKEN cDNA 1700086D15 gene
chr11_+_75732869 0.01 ENSMUST00000067664.3
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr18_+_37333853 0.01 ENSMUST00000061717.2
Pcdhb6
protocadherin beta 6
chr14_-_55671873 0.00 ENSMUST00000163750.1
ENSMUST00000010520.8
Nedd8
neural precursor cell expressed, developmentally down-regulated gene 8
chr11_+_62458414 0.00 ENSMUST00000014389.5
Pigl
phosphatidylinositol glycan anchor biosynthesis, class L

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa11_Hoxc12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.3 1.1 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.2 1.0 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.2 0.9 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.2 1.3 GO:0030242 pexophagy(GO:0030242)
0.2 0.5 GO:0048338 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) positive regulation of cardiac ventricle development(GO:1904414)
0.2 0.5 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.6 GO:0045425 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.1 0.6 GO:0015744 succinate transport(GO:0015744)
0.1 1.3 GO:0030035 microspike assembly(GO:0030035)
0.1 4.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.9 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.4 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1 0.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.3 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 0.6 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.7 GO:0060468 prevention of polyspermy(GO:0060468)
0.1 1.1 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.6 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.5 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.1 0.6 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.4 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 1.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.4 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.1 0.3 GO:0061344 atrioventricular node development(GO:0003162) coronary vein morphogenesis(GO:0003169) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of cell adhesion involved in heart morphogenesis(GO:0061344) positive regulation of ephrin receptor signaling pathway(GO:1901189) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.2 GO:0035709 defense response to nematode(GO:0002215) memory T cell activation(GO:0035709) positive regulation of memory T cell differentiation(GO:0043382) negative regulation of T-helper 1 cell differentiation(GO:0045626) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.3 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.2 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.0 0.3 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 1.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.6 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.8 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.2 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.7 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.4 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.9 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.5 GO:0010225 response to UV-C(GO:0010225)
0.0 0.2 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.5 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.0 0.1 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 1.0 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.5 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.3 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.4 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.3 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.3 GO:0021542 dentate gyrus development(GO:0021542)
0.0 1.8 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.5 GO:0006378 mRNA polyadenylation(GO:0006378)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0031417 NatC complex(GO:0031417)
0.3 0.8 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 1.1 GO:1990393 3M complex(GO:1990393)
0.2 0.5 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 1.0 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.3 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.9 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 1.3 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.0 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.7 GO:0005771 multivesicular body(GO:0005771)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 1.3 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.5 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.3 1.0 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.3 1.0 GO:0008940 nitrate reductase activity(GO:0008940)
0.2 1.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 0.7 GO:0032190 acrosin binding(GO:0032190)
0.2 1.8 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.2 0.6 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.2 0.6 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.2 1.1 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.2 0.8 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 0.8 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.6 GO:0019767 IgE receptor activity(GO:0019767)
0.1 0.4 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.9 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.5 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.9 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.4 GO:0070728 leucine binding(GO:0070728)
0.1 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.2 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.1 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.0 0.2 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.5 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.5 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 1.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0015100 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 1.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0070698 nodal binding(GO:0038100) type I activin receptor binding(GO:0070698)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism