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GSE58827: Dynamics of the Mouse Liver

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Results for Isl1

Z-value: 0.37

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Transcription factors associated with Isl1

Gene Symbol Gene ID Gene Info
Isl1
ENSMUSG00000042258.7 ISL1 transcription factor, LIM/homeodomain

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Isl1mm10_v2_chr13_-_116309639_1163096990.086.4e-01Click!

Activity profile of Isl1 motif

Sorted Z-values of Isl1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_105568298 0.98 ENSMUST00000005849.5
Agrp
agouti related protein
chrX_+_164090187 0.93 ENSMUST00000015545.3
Tmem27
transmembrane protein 27
chr10_-_19014549 0.59 ENSMUST00000146388.1
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr12_+_69963452 0.56 ENSMUST00000110560.1
Gm3086
predicted gene 3086
chr6_+_142298419 0.51 ENSMUST00000041993.2
Iapp
islet amyloid polypeptide
chr1_-_79440039 0.48 ENSMUST00000049972.4
Scg2
secretogranin II
chr13_+_76579670 0.45 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1
multiple C2 domains, transmembrane 1
chr18_-_68429235 0.44 ENSMUST00000052347.6
Mc2r
melanocortin 2 receptor
chr9_-_95815389 0.43 ENSMUST00000119760.1
Pls1
plastin 1 (I-isoform)
chr1_-_75133866 0.43 ENSMUST00000027405.4
Slc23a3
solute carrier family 23 (nucleobase transporters), member 3
chr3_-_75270073 0.41 ENSMUST00000039047.4
Serpini2
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr8_-_122460666 0.41 ENSMUST00000006762.5
Snai3
snail homolog 3 (Drosophila)
chr17_-_78684262 0.41 ENSMUST00000145480.1
Strn
striatin, calmodulin binding protein
chr14_+_124005355 0.41 ENSMUST00000166105.1
Gm17615
predicted gene, 17615
chr3_+_109573907 0.40 ENSMUST00000106576.2
Vav3
vav 3 oncogene
chr3_+_121531653 0.40 ENSMUST00000181070.1
A530020G20Rik
RIKEN cDNA A530020G20 gene
chr16_-_22161450 0.37 ENSMUST00000115379.1
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr13_-_23991158 0.36 ENSMUST00000021770.7
Scgn
secretagogin, EF-hand calcium binding protein
chr3_+_10088173 0.33 ENSMUST00000061419.7
Gm9833
predicted gene 9833
chr3_-_7613427 0.33 ENSMUST00000168269.2
Il7
interleukin 7
chr1_-_89933290 0.31 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr17_-_51810866 0.31 ENSMUST00000176669.1
Satb1
special AT-rich sequence binding protein 1
chr9_+_3404058 0.31 ENSMUST00000027027.5
Cwf19l2
CWF19-like 2, cell cycle control (S. pombe)
chr14_-_70630149 0.29 ENSMUST00000022694.9
Dmtn
dematin actin binding protein
chr4_-_82850721 0.28 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr2_+_125152505 0.28 ENSMUST00000110494.2
ENSMUST00000028630.2
ENSMUST00000110495.2
Slc12a1
solute carrier family 12, member 1
chr15_+_103018936 0.26 ENSMUST00000165375.1
Hoxc4
homeobox C4
chr7_-_28547109 0.25 ENSMUST00000057974.3
Nccrp1
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chrX_+_96455359 0.25 ENSMUST00000033553.7
Heph
hephaestin
chr3_+_84666192 0.25 ENSMUST00000107682.1
Tmem154
transmembrane protein 154
chr14_-_62761112 0.24 ENSMUST00000053959.6
Ints6
integrator complex subunit 6
chr6_-_24956106 0.23 ENSMUST00000127247.2
Tmem229a
transmembrane protein 229A
chr18_-_47333311 0.23 ENSMUST00000126684.1
ENSMUST00000156422.1
Sema6a
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr11_+_68692070 0.23 ENSMUST00000108673.1
Myh10
myosin, heavy polypeptide 10, non-muscle
chr9_+_53771499 0.22 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr13_-_103764502 0.22 ENSMUST00000074616.5
Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr10_-_35711891 0.21 ENSMUST00000080898.2
Amd2
S-adenosylmethionine decarboxylase 2
chrX_+_164140447 0.21 ENSMUST00000073973.4
Ace2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr4_-_42084291 0.21 ENSMUST00000177937.1
Gm21968
predicted gene, 21968
chr8_-_26119125 0.21 ENSMUST00000037182.7
Hook3
hook homolog 3 (Drosophila)
chrX_+_114474312 0.21 ENSMUST00000113371.1
ENSMUST00000040504.5
Klhl4
kelch-like 4
chr17_-_24533709 0.20 ENSMUST00000061764.7
Rab26
RAB26, member RAS oncogene family
chr19_-_53371766 0.20 ENSMUST00000086887.1
Gm10197
predicted gene 10197
chr18_+_69925542 0.20 ENSMUST00000080050.5
Ccdc68
coiled-coil domain containing 68
chr4_-_41045381 0.19 ENSMUST00000054945.7
Aqp7
aquaporin 7
chr2_-_58160495 0.18 ENSMUST00000028175.6
Cytip
cytohesin 1 interacting protein
chr15_-_34356421 0.17 ENSMUST00000179647.1
9430069I07Rik
RIKEN cDNA 9430069I07 gene
chr1_+_139422196 0.17 ENSMUST00000039867.7
Zbtb41
zinc finger and BTB domain containing 41 homolog
chrX_+_106920618 0.17 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr2_-_72986716 0.17 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr12_-_27342696 0.17 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chr3_-_127225917 0.16 ENSMUST00000182064.1
ENSMUST00000182662.1
Ank2
ankyrin 2, brain
chr9_+_35423582 0.16 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr3_+_116594959 0.16 ENSMUST00000029571.8
Sass6
spindle assembly 6 homolog (C. elegans)
chr11_-_76509419 0.16 ENSMUST00000094012.4
Abr
active BCR-related gene
chr9_-_112217261 0.15 ENSMUST00000159451.1
ENSMUST00000162796.1
ENSMUST00000161097.1
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr3_-_127225847 0.15 ENSMUST00000182726.1
ENSMUST00000182779.1
Ank2
ankyrin 2, brain
chr13_+_93308006 0.15 ENSMUST00000079086.6
Homer1
homer homolog 1 (Drosophila)
chr9_-_40346290 0.15 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr11_-_86357570 0.15 ENSMUST00000043624.8
Med13
mediator complex subunit 13
chr8_+_84723003 0.15 ENSMUST00000098571.4
G430095P16Rik
RIKEN cDNA G430095P16 gene
chr17_-_45733843 0.15 ENSMUST00000178179.1
1600014C23Rik
RIKEN cDNA 1600014C23 gene
chr5_+_136057267 0.13 ENSMUST00000006303.4
ENSMUST00000156530.1
Upk3bl
uroplakin 3B-like
chr6_+_30568367 0.13 ENSMUST00000049251.5
Cpa4
carboxypeptidase A4
chr13_+_76579681 0.12 ENSMUST00000109589.2
Mctp1
multiple C2 domains, transmembrane 1
chr4_+_108719649 0.12 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr5_-_5266038 0.12 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
Cdk14
cyclin-dependent kinase 14
chr11_-_6230127 0.12 ENSMUST00000004505.2
Npc1l1
NPC1-like 1
chr13_-_75943812 0.12 ENSMUST00000022078.5
ENSMUST00000109606.1
Rhobtb3
Rho-related BTB domain containing 3
chr14_+_52844465 0.12 ENSMUST00000181360.1
ENSMUST00000183652.1
Trav12d-1
T cell receptor alpha variable 12D-1
chr14_+_53640701 0.11 ENSMUST00000179267.2
Trav14-2
T cell receptor alpha variable 14-2
chr15_-_50889691 0.11 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1
trichorhinophalangeal syndrome I (human)
chr1_-_183147461 0.11 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr4_-_137118135 0.11 ENSMUST00000154285.1
Gm13001
predicted gene 13001
chr16_+_36693972 0.11 ENSMUST00000023617.6
ENSMUST00000089618.3
Ildr1
immunoglobulin-like domain containing receptor 1
chr3_-_104818539 0.11 ENSMUST00000106774.1
ENSMUST00000106775.1
ENSMUST00000166979.1
ENSMUST00000136148.1
Mov10
Moloney leukemia virus 10
chr9_+_113812547 0.10 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2
CLIP associating protein 2
chr19_-_8218832 0.10 ENSMUST00000113298.2
Slc22a29
solute carrier family 22. member 29
chr10_-_70655934 0.10 ENSMUST00000162144.1
ENSMUST00000162793.1
Phyhipl
phytanoyl-CoA hydroxylase interacting protein-like
chr18_-_6490808 0.10 ENSMUST00000028100.6
ENSMUST00000050542.5
Epc1
enhancer of polycomb homolog 1 (Drosophila)
chr8_-_33747724 0.10 ENSMUST00000179364.1
Smim18
small integral membrane protein 18
chr10_+_69534208 0.10 ENSMUST00000182439.1
ENSMUST00000092434.5
ENSMUST00000092432.5
ENSMUST00000092431.5
ENSMUST00000054167.8
ENSMUST00000047061.6
Ank3
ankyrin 3, epithelial
chr13_+_56703504 0.10 ENSMUST00000109874.1
Smad5
SMAD family member 5
chr16_+_36694024 0.10 ENSMUST00000119464.1
Ildr1
immunoglobulin-like domain containing receptor 1
chr4_-_14621805 0.09 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr2_+_162943474 0.09 ENSMUST00000035751.5
ENSMUST00000156954.1
L3mbtl1
l(3)mbt-like (Drosophila)
chr11_-_69822144 0.09 ENSMUST00000045771.6
Spem1
sperm maturation 1
chr18_-_15718046 0.08 ENSMUST00000053017.6
Chst9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr3_-_25212720 0.08 ENSMUST00000091289.3
Gm10259
predicted pseudogene 10259
chrX_-_136780141 0.08 ENSMUST00000018739.4
Glra4
glycine receptor, alpha 4 subunit
chr2_+_120476911 0.08 ENSMUST00000110716.1
ENSMUST00000028748.6
ENSMUST00000090028.5
ENSMUST00000110719.2
Capn3
calpain 3
chrX_-_23285532 0.08 ENSMUST00000115319.2
Klhl13
kelch-like 13
chr3_-_150073620 0.08 ENSMUST00000057740.5
Rpsa-ps10
ribosomal protein SA, pseudogene 10
chr15_-_93519499 0.08 ENSMUST00000109255.2
Prickle1
prickle homolog 1 (Drosophila)
chr10_-_13388753 0.08 ENSMUST00000105546.1
Phactr2
phosphatase and actin regulator 2
chr14_-_78536762 0.07 ENSMUST00000123853.1
Akap11
A kinase (PRKA) anchor protein 11
chrX_+_153237748 0.07 ENSMUST00000112574.2
Klf8
Kruppel-like factor 8
chrX_+_56779437 0.07 ENSMUST00000114773.3
Fhl1
four and a half LIM domains 1
chr2_+_158794807 0.07 ENSMUST00000029186.7
ENSMUST00000109478.2
ENSMUST00000156893.1
Dhx35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr10_+_26772477 0.07 ENSMUST00000039557.7
Arhgap18
Rho GTPase activating protein 18
chr8_-_61902669 0.07 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld
palladin, cytoskeletal associated protein
chr9_-_44767792 0.07 ENSMUST00000034607.9
Arcn1
archain 1
chr2_-_71367749 0.07 ENSMUST00000151937.1
Slc25a12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr6_-_129451906 0.07 ENSMUST00000037481.7
Clec1a
C-type lectin domain family 1, member a
chr4_-_137766474 0.07 ENSMUST00000139951.1
Alpl
alkaline phosphatase, liver/bone/kidney
chrX_-_153037549 0.07 ENSMUST00000051484.3
Mageh1
melanoma antigen, family H, 1
chr16_-_64786321 0.06 ENSMUST00000052588.4
Zfp654
zinc finger protein 654
chr19_-_8839181 0.06 ENSMUST00000096259.4
Gng3
guanine nucleotide binding protein (G protein), gamma 3
chr11_+_68692097 0.06 ENSMUST00000018887.8
Myh10
myosin, heavy polypeptide 10, non-muscle
chr4_+_3940747 0.06 ENSMUST00000119403.1
Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr3_+_103832562 0.06 ENSMUST00000062945.5
Bcl2l15
BCLl2-like 15
chr4_+_94739276 0.06 ENSMUST00000073939.6
ENSMUST00000102798.1
Tek
endothelial-specific receptor tyrosine kinase
chr11_-_4594750 0.06 ENSMUST00000109943.3
Mtmr3
myotubularin related protein 3
chr2_-_72813665 0.06 ENSMUST00000136807.1
ENSMUST00000148327.1
6430710C18Rik
RIKEN cDNA 6430710C18 gene
chr4_-_120951664 0.06 ENSMUST00000106280.1
Zfp69
zinc finger protein 69
chr2_+_71211941 0.06 ENSMUST00000112144.2
ENSMUST00000100028.3
ENSMUST00000112136.1
Dync1i2
dynein cytoplasmic 1 intermediate chain 2
chr19_+_55741884 0.06 ENSMUST00000111658.3
ENSMUST00000111654.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr12_-_72408934 0.06 ENSMUST00000078505.7
Rtn1
reticulon 1
chr10_+_40349265 0.05 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19
cyclin-dependent kinase 19
chr11_-_99374895 0.05 ENSMUST00000006963.2
Krt28
keratin 28
chr10_-_44458715 0.04 ENSMUST00000039174.4
Prdm1
PR domain containing 1, with ZNF domain
chr3_+_89520152 0.04 ENSMUST00000000811.7
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr4_-_94650092 0.04 ENSMUST00000107101.1
Lrrc19
leucine rich repeat containing 19
chrX_+_71981522 0.04 ENSMUST00000114569.1
Fate1
fetal and adult testis expressed 1
chrX_+_99975570 0.04 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda
ectodysplasin-A
chr7_-_118116128 0.04 ENSMUST00000128482.1
ENSMUST00000131840.1
Rps15a
ribosomal protein S15A
chr5_+_121777929 0.04 ENSMUST00000160821.1
Atxn2
ataxin 2
chr15_+_44196135 0.04 ENSMUST00000038856.6
ENSMUST00000110289.3
Trhr
thyrotropin releasing hormone receptor
chr5_-_107875035 0.04 ENSMUST00000138111.1
ENSMUST00000112642.1
Evi5
ecotropic viral integration site 5
chr12_-_12941827 0.04 ENSMUST00000043396.7
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr15_-_50882806 0.04 ENSMUST00000184885.1
Trps1
trichorhinophalangeal syndrome I (human)
chr2_-_152398046 0.04 ENSMUST00000063332.8
ENSMUST00000182625.1
Sox12
SRY-box containing gene 12
chr7_-_118116171 0.04 ENSMUST00000131374.1
Rps15a
ribosomal protein S15A
chr4_+_74013442 0.03 ENSMUST00000098006.2
ENSMUST00000084474.5
Frmd3
FERM domain containing 3
chr1_+_87803638 0.03 ENSMUST00000077772.5
ENSMUST00000177757.1
Sag
S-antigen, retina and pineal gland (arrestin)
chr6_+_139843648 0.03 ENSMUST00000087657.6
Pik3c2g
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
chr12_-_113422730 0.03 ENSMUST00000177715.1
ENSMUST00000103426.1
Ighm
immunoglobulin heavy constant mu
chr5_-_93045022 0.03 ENSMUST00000061328.5
Sowahb
sosondowah ankyrin repeat domain family member B
chr19_-_37176055 0.03 ENSMUST00000142973.1
ENSMUST00000154376.1
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr1_-_57970067 0.03 ENSMUST00000164963.1
Kctd18
potassium channel tetramerisation domain containing 18
chr1_-_57970104 0.03 ENSMUST00000114410.3
Kctd18
potassium channel tetramerisation domain containing 18
chr11_-_60913775 0.02 ENSMUST00000019075.3
Gm16515
predicted gene, Gm16515
chr8_+_83666827 0.02 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr19_+_55741810 0.02 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr15_+_102990576 0.02 ENSMUST00000001703.6
Hoxc8
homeobox C8
chr10_+_18469958 0.02 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1
NHS-like 1
chr19_+_55742056 0.02 ENSMUST00000111659.2
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr9_-_112187898 0.02 ENSMUST00000178410.1
ENSMUST00000172380.3
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr17_+_27856443 0.01 ENSMUST00000114849.1
Uhrf1bp1
UHRF1 (ICBP90) binding protein 1
chr2_-_127788854 0.01 ENSMUST00000028857.7
ENSMUST00000110357.1
Nphp1
nephronophthisis 1 (juvenile) homolog (human)
chr1_-_162898484 0.01 ENSMUST00000143123.1
Fmo2
flavin containing monooxygenase 2
chr16_-_97170707 0.01 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr18_+_4375583 0.01 ENSMUST00000025077.6
Mtpap
mitochondrial poly(A) polymerase
chr4_-_126325641 0.01 ENSMUST00000131113.1
Tekt2
tektin 2
chr14_-_52237572 0.01 ENSMUST00000089752.4
Chd8
chromodomain helicase DNA binding protein 8
chr1_+_12718496 0.01 ENSMUST00000088585.3
Sulf1
sulfatase 1
chr8_+_25720054 0.01 ENSMUST00000068916.8
ENSMUST00000139836.1
Ppapdc1b
phosphatidic acid phosphatase type 2 domain containing 1B
chrX_+_169879596 0.01 ENSMUST00000112105.1
ENSMUST00000078947.5
Mid1
midline 1
chr8_-_54718664 0.01 ENSMUST00000144711.2
ENSMUST00000093510.2
Wdr17
WD repeat domain 17
chr4_-_58009117 0.00 ENSMUST00000102897.3
Txndc8
thioredoxin domain containing 8
chr5_-_37824580 0.00 ENSMUST00000063116.9
Msx1
msh homeobox 1
chr17_-_35046539 0.00 ENSMUST00000007250.7
Msh5
mutS homolog 5 (E. coli)

Network of associatons between targets according to the STRING database.

First level regulatory network of Isl1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0070429 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.9 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 1.0 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.3 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.3 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.5 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.3 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 0.2 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.0 0.2 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.3 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.2 GO:0015793 glycerol transport(GO:0015793) renal water absorption(GO:0070295)
0.0 0.5 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.3 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.3 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.0 0.1 GO:0070315 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.1 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.0 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.0 0.8 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 0.0 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.2 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:0097513 myosin II filament(GO:0097513)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 1.2 GO:0031526 brush border membrane(GO:0031526)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.3 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.1 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.4 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 0.2 GO:0019002 GMP binding(GO:0019002)
0.1 0.2 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0019808 polyamine binding(GO:0019808)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.5 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade