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GSE58827: Dynamics of the Mouse Liver

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Results for Jun

Z-value: 1.26

Motif logo

Transcription factors associated with Jun

Gene Symbol Gene ID Gene Info
ENSMUSG00000052684.3 jun proto-oncogene

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Junmm10_v2_chr4_-_95052188_950522220.095.9e-01Click!

Activity profile of Jun motif

Sorted Z-values of Jun motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_65968483 14.77 ENSMUST00000022616.6
clusterin
chr9_-_86695897 9.71 ENSMUST00000034989.8
malic enzyme 1, NADP(+)-dependent, cytosolic
chr1_+_182564994 9.64 ENSMUST00000048941.7
ENSMUST00000168514.1
calpain 8
chr7_-_141276729 9.58 ENSMUST00000167263.1
ENSMUST00000080654.5
cadherin-related family member 5
chr4_+_63356152 7.97 ENSMUST00000006687.4
orosomucoid 3
chr8_-_5105232 7.60 ENSMUST00000023835.1
solute carrier family 10, member 2
chr5_-_87254804 7.40 ENSMUST00000075858.3
UDP glucuronosyltransferase 2 family, polypeptide B37
chr9_+_86695542 6.67 ENSMUST00000150367.2
RIKEN cDNA A330041J22 gene
chr10_+_128933782 6.57 ENSMUST00000099112.2
integrin alpha 7
chr1_-_180193475 6.44 ENSMUST00000160482.1
ENSMUST00000170472.1
aarF domain containing kinase 3
chr14_+_66635251 6.36 ENSMUST00000159365.1
ENSMUST00000054661.1
ENSMUST00000159068.1
adrenergic receptor, alpha 1a
chr3_+_138217814 6.32 ENSMUST00000090171.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_-_166309585 6.32 ENSMUST00000168347.1
RIKEN cDNA 5330438I03 gene
chr12_-_103904887 6.26 ENSMUST00000074051.5
serine (or cysteine) peptidase inhibitor, clade A, member 1C
chr12_-_103773592 6.08 ENSMUST00000078869.5
serine (or cysteine) peptidase inhibitor, clade A, member 1D
chr9_+_7445822 6.00 ENSMUST00000034497.6
matrix metallopeptidase 3
chr9_-_120023558 5.92 ENSMUST00000111635.2
xin actin-binding repeat containing 1
chr6_+_17463927 5.74 ENSMUST00000115442.1
met proto-oncogene
chr1_+_107589997 5.48 ENSMUST00000112706.2
ENSMUST00000000514.4
serine (or cysteine) peptidase inhibitor, clade B, member 8
chr7_+_127800844 5.31 ENSMUST00000106271.1
ENSMUST00000138432.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr8_-_110039330 5.11 ENSMUST00000109222.2
carbohydrate (chondroitin 6/keratan) sulfotransferase 4
chr5_-_24758008 5.03 ENSMUST00000047119.4
crystallin, gamma N
chr12_-_103956891 4.90 ENSMUST00000085054.4
serine (or cysteine) peptidase inhibitor, clade A, member 1E
chr7_-_29248375 4.59 ENSMUST00000032808.4
RIKEN cDNA 2200002D01 gene
chr5_-_66080971 4.52 ENSMUST00000127275.1
ENSMUST00000113724.1
RNA binding motif protein 47
chr1_-_180193653 4.51 ENSMUST00000159914.1
aarF domain containing kinase 3
chr3_+_100825452 4.50 ENSMUST00000054791.7
V-set domain containing T cell activation inhibitor 1
chr2_-_25461021 4.46 ENSMUST00000151239.1
cDNA sequence BC029214
chr2_-_25461094 4.45 ENSMUST00000114261.2
cDNA sequence BC029214
chr12_-_103863551 4.41 ENSMUST00000085056.6
ENSMUST00000072876.5
ENSMUST00000124717.1
serine (or cysteine) peptidase inhibitor, clade A, member 1A
chr19_+_8989277 4.33 ENSMUST00000092955.3
ENSMUST00000092956.2
AHNAK nucleoprotein (desmoyokin)
chr19_-_4042165 4.18 ENSMUST00000042700.9
glutathione S-transferase, pi 2
chr7_+_30553263 4.17 ENSMUST00000044048.7
heat shock protein, alpha-crystallin-related, B6
chr10_-_128589650 4.14 ENSMUST00000082059.6
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
chr17_+_43953191 4.10 ENSMUST00000044792.4
regulator of calcineurin 2
chr11_+_76904475 4.02 ENSMUST00000142166.1
transmembrane and immunoglobulin domain containing 1
chr13_+_30659999 4.02 ENSMUST00000091672.6
ENSMUST00000110310.1
ENSMUST00000095914.5
dual specificity phosphatase 22
chr7_-_80401707 3.98 ENSMUST00000120753.1
furin (paired basic amino acid cleaving enzyme)
chr9_+_7347374 3.94 ENSMUST00000065079.5
ENSMUST00000005950.5
matrix metallopeptidase 12
chr3_+_123267445 3.89 ENSMUST00000047923.7
Sec24 related gene family, member D (S. cerevisiae)
chr14_+_27622433 3.88 ENSMUST00000090302.5
ELKS/RAB6-interacting/CAST family member 2
chr2_+_69380431 3.87 ENSMUST00000063690.3
dehydrogenase/reductase (SDR family) member 9
chr15_-_3303521 3.86 ENSMUST00000165386.1
coiled-coil domain containing 152
chr7_+_141338880 3.84 ENSMUST00000026577.6
EPS8-like 2
chr4_-_140665891 3.82 ENSMUST00000069623.5
Rho guanine nucleotide exchange factor (GEF) 10-like
chr6_+_17463749 3.81 ENSMUST00000115443.1
met proto-oncogene
chr12_-_103738158 3.76 ENSMUST00000095450.4
serine (or cysteine) preptidase inhibitor, clade A, member 1B
chr10_+_127776374 3.74 ENSMUST00000136223.1
ENSMUST00000052652.6
retinol dehydrogenase 9
chr7_-_133782721 3.74 ENSMUST00000063669.1
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr7_-_127946725 3.73 ENSMUST00000118755.1
ENSMUST00000094026.3
protease, serine, 36
chr8_+_36489191 3.68 ENSMUST00000171777.1
RIKEN cDNA 6430573F11 gene
chr3_+_121723515 3.66 ENSMUST00000029771.8
coagulation factor III
chr17_+_43952999 3.64 ENSMUST00000177857.1
regulator of calcineurin 2
chr18_-_31820413 3.63 ENSMUST00000165131.2
predicted gene 6665
chr11_-_60036917 3.58 ENSMUST00000102692.3
phosphatidylethanolamine N-methyltransferase
chr18_+_20944607 3.58 ENSMUST00000050004.1
ring finger protein 125
chr15_-_74728011 3.57 ENSMUST00000023261.2
secreted Ly6/Plaur domain containing 1
chr1_+_87594545 3.57 ENSMUST00000165109.1
ENSMUST00000070898.5
neuraminidase 2
chr2_+_162987502 3.52 ENSMUST00000117123.1
serum/glucocorticoid regulated kinase 2
chr1_+_165769392 3.48 ENSMUST00000040298.4
cellular repressor of E1A-stimulated genes 1
chr5_-_86518578 3.43 ENSMUST00000134179.1
transmembrane protease, serine 11g
chr1_-_155527083 3.42 ENSMUST00000097531.2
predicted gene 5532
chr11_+_101082565 3.40 ENSMUST00000001806.3
ENSMUST00000107308.3
Coenzyme A synthase
chr2_+_162987330 3.38 ENSMUST00000018012.7
serum/glucocorticoid regulated kinase 2
chr7_-_44670820 3.37 ENSMUST00000048102.7
myosin, heavy polypeptide 14
chr9_-_106476372 3.34 ENSMUST00000123555.1
ENSMUST00000125850.1
poly (ADP-ribose) polymerase family, member 3
chr10_-_44004846 3.31 ENSMUST00000020017.8
absent in melanoma 1
chr19_+_5877794 3.29 ENSMUST00000145200.1
ENSMUST00000025732.7
ENSMUST00000125114.1
ENSMUST00000155697.1
solute carrier family 25, member 45
chrX_+_98149666 3.27 ENSMUST00000052837.7
androgen receptor
chr3_-_85722474 3.27 ENSMUST00000119077.1
family with sequence similarity 160, member A1
chr18_-_35627223 3.22 ENSMUST00000025212.5
solute carrier family 23 (nucleobase transporters), member 1
chr6_+_17463826 3.19 ENSMUST00000140070.1
met proto-oncogene
chr4_+_152008803 3.07 ENSMUST00000097773.3
kelch-like 21
chr9_-_106476590 3.05 ENSMUST00000112479.2
poly (ADP-ribose) polymerase family, member 3
chr17_-_31165045 3.03 ENSMUST00000024831.6
trefoil factor 1
chr7_-_126584220 2.99 ENSMUST00000128970.1
ENSMUST00000116269.2
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr5_-_108675569 2.96 ENSMUST00000051757.7
solute carrier family 26 (sulfate transporter), member 1
chr17_+_85028347 2.94 ENSMUST00000024944.7
solute carrier family 3, member 1
chr15_-_76014318 2.92 ENSMUST00000060807.5
family with sequence similarity 83, member H
chr6_+_124996681 2.91 ENSMUST00000032479.4
PILR alpha associated neural protein
chr17_+_26113286 2.88 ENSMUST00000025010.7
transmembrane protein 8 (five membrane-spanning domains)
chr7_+_67647405 2.86 ENSMUST00000032774.8
ENSMUST00000107471.1
tetratricopeptide repeat domain 23
chr7_-_4971168 2.85 ENSMUST00000133272.1
predicted gene 1078
chr6_-_3968357 2.80 ENSMUST00000031674.8
tissue factor pathway inhibitor 2
chr4_-_148151646 2.78 ENSMUST00000132083.1
F-box protein 6
chrX_+_7722267 2.74 ENSMUST00000125991.1
ENSMUST00000148624.1
WD repeat domain 45
chr7_+_141338963 2.67 ENSMUST00000143633.1
EPS8-like 2
chrX_-_147429189 2.61 ENSMUST00000033646.2
interleukin 13 receptor, alpha 2
chrX_-_74023745 2.60 ENSMUST00000114353.3
ENSMUST00000101458.2
interleukin-1 receptor-associated kinase 1
chrX_+_7722214 2.55 ENSMUST00000043045.2
ENSMUST00000116634.1
ENSMUST00000115689.3
ENSMUST00000131077.1
ENSMUST00000115688.1
ENSMUST00000116633.1
WD repeat domain 45
chr10_-_81427114 2.53 ENSMUST00000078185.7
ENSMUST00000020461.8
ENSMUST00000105321.3
nuclear factor I/C
chr12_-_85288419 2.47 ENSMUST00000121930.1
acylphosphatase 1, erythrocyte (common) type
chr18_-_35498856 2.46 ENSMUST00000025215.8
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr2_+_25395866 2.42 ENSMUST00000028328.2
ectonucleoside triphosphate diphosphohydrolase 2
chr13_-_8871751 2.40 ENSMUST00000175958.1
WD repeat domain 37
chr9_+_7272514 2.38 ENSMUST00000015394.8
matrix metallopeptidase 13
chr11_-_50210765 2.37 ENSMUST00000143379.1
ENSMUST00000015981.5
ENSMUST00000102774.4
sequestosome 1
chr4_-_140648736 2.36 ENSMUST00000039204.3
ENSMUST00000105799.1
ENSMUST00000097820.2
Rho guanine nucleotide exchange factor (GEF) 10-like
chrX_+_164269371 2.35 ENSMUST00000145412.1
ENSMUST00000033749.7
pirin
chr13_-_54611274 2.31 ENSMUST00000049575.7
clathrin, light polypeptide (Lcb)
chr15_-_3979432 2.30 ENSMUST00000022791.8
F-box protein 4
chr15_-_11399594 2.29 ENSMUST00000022849.5
threonyl-tRNA synthetase
chr11_+_87592145 2.29 ENSMUST00000103179.3
ENSMUST00000092802.5
ENSMUST00000146871.1
myotubularin related protein 4
chr2_+_143915273 2.28 ENSMUST00000103172.3
destrin
chr15_+_44196135 2.26 ENSMUST00000038856.6
ENSMUST00000110289.3
thyrotropin releasing hormone receptor
chr2_+_160880642 2.21 ENSMUST00000109456.2
lipin 3
chr13_+_75839868 2.20 ENSMUST00000022082.7
glutaredoxin
chr9_+_37613806 2.20 ENSMUST00000002007.3
sialic acid acetylesterase
chr16_-_56717446 2.19 ENSMUST00000065515.7
Trk-fused gene
chr13_-_54611332 2.17 ENSMUST00000091609.4
clathrin, light polypeptide (Lcb)
chr17_-_23998094 2.16 ENSMUST00000041649.6
protease, serine, 22
chr4_-_45489794 2.16 ENSMUST00000146236.1
src homology 2 domain-containing transforming protein B
chr14_-_34310503 2.15 ENSMUST00000111917.1
family with sequence similarity 35, member A
chr19_-_11818806 2.14 ENSMUST00000075304.6
syntaxin 3
chr6_+_82052307 2.13 ENSMUST00000149023.1
eva-1 homolog A (C. elegans)
chr2_-_77703252 2.12 ENSMUST00000171063.1
zinc finger protein 385B
chr4_-_141723401 2.10 ENSMUST00000102484.4
ENSMUST00000177592.1
DNA-damage inducible protein 2
regulatory solute carrier protein, family 1, member 1
chr11_+_94328242 2.07 ENSMUST00000021227.5
ankyrin repeat domain 40
chr11_+_121146143 2.04 ENSMUST00000039088.8
ENSMUST00000155694.1
testis expressed gene 19.1
chr16_-_56717286 2.01 ENSMUST00000121554.1
ENSMUST00000128551.1
Trk-fused gene
chr1_+_33908172 1.99 ENSMUST00000182513.1
ENSMUST00000183034.1
dystonin
chr15_-_91049823 1.97 ENSMUST00000088614.5
ENSMUST00000100304.4
ENSMUST00000067205.8
ENSMUST00000109288.2
ENSMUST00000109287.2
kinesin family member 21A
chr3_-_88177671 1.97 ENSMUST00000181837.1
RIKEN cDNA 1700113A16 gene
chr5_-_62766153 1.96 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_+_9118070 1.96 ENSMUST00000020677.1
ENSMUST00000101525.2
ENSMUST00000170444.1
uridine phosphorylase 1
chr16_+_90220742 1.96 ENSMUST00000023707.9
superoxide dismutase 1, soluble
chr1_+_164115264 1.95 ENSMUST00000162746.1
selectin, platelet
chr17_-_24644933 1.94 ENSMUST00000019684.5
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chrX_-_74023908 1.94 ENSMUST00000033769.8
ENSMUST00000114352.1
ENSMUST00000068286.5
ENSMUST00000114360.3
ENSMUST00000114354.3
interleukin-1 receptor-associated kinase 1
chr7_-_126584578 1.93 ENSMUST00000150311.1
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr11_+_94327984 1.89 ENSMUST00000107818.2
ENSMUST00000051221.6
ankyrin repeat domain 40
chr19_-_36736653 1.84 ENSMUST00000087321.2
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr2_-_102400863 1.84 ENSMUST00000102573.1
tripartite motif-containing 44
chr5_-_148552783 1.82 ENSMUST00000079324.7
ENSMUST00000164904.1
ubiquitin-like 3
chr7_-_18432033 1.82 ENSMUST00000019291.6
pregnancy-specific glycoprotein 28
chr13_-_119738394 1.82 ENSMUST00000178973.1
serine/threonine-protein kinase NIM1
chr11_-_120630516 1.80 ENSMUST00000106181.1
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr4_-_148151878 1.80 ENSMUST00000105706.1
ENSMUST00000030858.7
ENSMUST00000134261.1
F-box protein 6
chr2_+_152105722 1.78 ENSMUST00000099225.2
sulfiredoxin 1 homolog (S. cerevisiae)
chr9_-_20728219 1.77 ENSMUST00000034692.7
olfactomedin 2
chr2_+_69670100 1.75 ENSMUST00000100050.3
kelch-like 41
chrX_-_8132770 1.75 ENSMUST00000130832.1
ENSMUST00000033506.6
ENSMUST00000115623.1
ENSMUST00000153839.1
WD repeat domain 13
chrX_+_73675500 1.73 ENSMUST00000171398.1
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr2_+_167421706 1.69 ENSMUST00000047815.6
ENSMUST00000109218.1
ENSMUST00000073873.3
solute carrier family 9 (sodium/hydrogen exchanger), member 8
chr14_-_55758458 1.69 ENSMUST00000001497.7
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chr9_+_108953597 1.68 ENSMUST00000026740.5
collagen, type VII, alpha 1
chr11_+_76904513 1.67 ENSMUST00000072633.3
transmembrane and immunoglobulin domain containing 1
chr7_-_68353182 1.66 ENSMUST00000123509.1
ENSMUST00000129965.1
predicted gene 16158
chr8_-_61591130 1.65 ENSMUST00000135439.1
ENSMUST00000121200.1
palladin, cytoskeletal associated protein
chr11_-_70015346 1.65 ENSMUST00000018718.7
ENSMUST00000102574.3
acyl-Coenzyme A dehydrogenase, very long chain
chr2_+_145785980 1.63 ENSMUST00000110005.1
ENSMUST00000094480.4
Ras and Rab interactor 2
chr3_-_57294880 1.61 ENSMUST00000171384.1
transmembrane 4 superfamily member 1
chr14_+_120478443 1.60 ENSMUST00000062117.6
RAS related protein 2a
chr11_+_87582201 1.60 ENSMUST00000133202.1
septin 4
chr4_+_42158092 1.58 ENSMUST00000098122.2
predicted gene 13306
chr11_+_95842283 1.57 ENSMUST00000107714.2
ENSMUST00000107711.1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr11_+_117232254 1.57 ENSMUST00000106354.2
septin 9
chr2_-_103372725 1.56 ENSMUST00000139065.1
RIKEN cDNA A930006I01 gene
chr7_-_101581161 1.53 ENSMUST00000063920.2
ADP-ribosyltransferase 2b
chr15_-_97767644 1.53 ENSMUST00000128775.2
ENSMUST00000134885.2
Rap guanine nucleotide exchange factor (GEF) 3
chr10_+_26078255 1.52 ENSMUST00000041011.3
predicted gene 9767
chr7_+_127244511 1.51 ENSMUST00000052509.4
zinc finger protein 771
chr7_+_55842071 1.51 ENSMUST00000032629.9
ENSMUST00000173783.1
ENSMUST00000085255.4
ENSMUST00000163845.2
cytoplasmic FMR1 interacting protein 1
chr11_-_120467414 1.49 ENSMUST00000076921.6
ADP-ribosylation factor-like 16
chr15_-_33687840 1.47 ENSMUST00000042021.3
testis-specific protein, Y-encoded-like 5
chr8_+_107293500 1.45 ENSMUST00000151114.1
ENSMUST00000075922.4
ENSMUST00000125721.1
nuclear factor of activated T cells 5
chr8_-_105966038 1.44 ENSMUST00000116429.2
ENSMUST00000034370.9
solute carrier family 12, member 4
chr16_+_20548577 1.41 ENSMUST00000003319.5
ATP-binding cassette, sub-family F (GCN20), member 3
chr14_+_101840602 1.40 ENSMUST00000159314.1
LIM domain only 7
chr9_+_32224246 1.40 ENSMUST00000168954.2
Rho GTPase activating protein 32
chr3_-_89402650 1.40 ENSMUST00000168325.1
ENSMUST00000057431.5
lens epithelial protein
chr17_-_42742167 1.38 ENSMUST00000113614.2
G protein-coupled receptor 111
chr2_+_11705712 1.37 ENSMUST00000138856.1
ENSMUST00000078834.5
ENSMUST00000114834.3
ENSMUST00000114833.3
ENSMUST00000114831.2
ENSMUST00000114832.2
interleukin 15 receptor, alpha chain
chr6_-_113434757 1.37 ENSMUST00000113091.1
cell death-inducing DFFA-like effector c
chr2_+_20737306 1.36 ENSMUST00000114606.1
ENSMUST00000114608.1
enhancer trap locus 4
chr11_-_31671863 1.35 ENSMUST00000058060.7
biorientation of chromosomes in cell division 1
chr6_-_122856151 1.35 ENSMUST00000042081.8
complement component 3a receptor 1
chr1_+_128244122 1.34 ENSMUST00000027592.3
UBX domain protein 4
chr14_-_8259325 1.34 ENSMUST00000164598.1
acyl-Coenzyme A oxidase 2, branched chain
chr11_-_97150025 1.34 ENSMUST00000118375.1
TBK1 binding protein 1
chr11_+_95842668 1.30 ENSMUST00000100532.3
ENSMUST00000036088.4
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr6_-_113434529 1.30 ENSMUST00000133348.1
cell death-inducing DFFA-like effector c
chr5_+_117363513 1.30 ENSMUST00000111959.1
WD repeat and SOCS box-containing 2
chr9_-_109059216 1.29 ENSMUST00000112053.1
three prime repair exonuclease 1
chr7_-_4970961 1.28 ENSMUST00000144863.1
predicted gene 1078
chr11_-_95842409 1.27 ENSMUST00000059026.3
ABI gene family, member 3
chr2_+_11705437 1.25 ENSMUST00000148748.1
interleukin 15 receptor, alpha chain
chr14_-_8258800 1.23 ENSMUST00000022271.7
acyl-Coenzyme A oxidase 2, branched chain
chr11_+_73267388 1.23 ENSMUST00000049676.2
transient receptor potential cation channel, subfamily V, member 3
chr10_+_86779000 1.23 ENSMUST00000099396.2
5'-nucleotidase domain containing 3
chr9_+_108953578 1.22 ENSMUST00000112070.1
collagen, type VII, alpha 1
chr11_+_80428598 1.21 ENSMUST00000173938.1
ENSMUST00000017572.7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr11_-_93968293 1.21 ENSMUST00000170303.1
predicted gene 20390
chr10_+_24447468 1.21 ENSMUST00000134627.1
predicted gene 15271
chr2_+_11705355 1.20 ENSMUST00000128156.2
interleukin 15 receptor, alpha chain
chr11_-_93968242 1.20 ENSMUST00000107844.2
NME/NM23 nucleoside diphosphate kinase 1
chr18_+_61639542 1.19 ENSMUST00000183083.1
ENSMUST00000183087.1
predicted gene, 20748
chr12_+_75308308 1.19 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
ras homolog gene family, member J
chr17_-_45592485 1.17 ENSMUST00000166119.1
solute carrier family 29 (nucleoside transporters), member 1
chr1_-_120074023 1.15 ENSMUST00000056089.7
transmembrane protein 37

Network of associatons between targets according to the STRING database.

First level regulatory network of Jun

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 14.8 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
2.1 6.4 GO:1990166 protein localization to site of double-strand break(GO:1990166)
2.1 6.4 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
1.9 9.6 GO:1904970 brush border assembly(GO:1904970)
1.8 12.7 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
1.7 5.1 GO:0042339 keratan sulfate metabolic process(GO:0042339)
1.6 6.3 GO:0006069 ethanol oxidation(GO:0006069)
1.4 9.7 GO:0006108 malate metabolic process(GO:0006108) regulation of NADP metabolic process(GO:1902031)
1.2 3.7 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
1.1 3.3 GO:0060748 lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
1.1 7.6 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.1 3.2 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
1.0 4.0 GO:0090472 dibasic protein processing(GO:0090472)
1.0 4.9 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.8 2.3 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.7 2.0 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.7 3.9 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.7 2.6 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.6 4.5 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.6 6.0 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.6 3.6 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.6 2.4 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.6 5.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.6 1.7 GO:0015881 creatine transport(GO:0015881)
0.6 2.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.5 4.5 GO:0072602 interleukin-4 secretion(GO:0072602) positive regulation of interleukin-2 secretion(GO:1900042)
0.5 6.0 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.5 4.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.5 14.0 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.4 3.6 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.4 2.6 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.4 2.0 GO:0046133 pyrimidine ribonucleoside catabolic process(GO:0046133)
0.4 1.1 GO:0071873 response to norepinephrine(GO:0071873)
0.4 3.0 GO:0019532 oxalate transport(GO:0019532)
0.3 1.0 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.3 3.7 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.3 2.2 GO:0015862 uridine transport(GO:0015862)
0.3 2.2 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.3 1.5 GO:0019364 pyridine nucleotide catabolic process(GO:0019364)
0.3 1.2 GO:0035938 estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864)
0.3 2.4 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.3 2.6 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.3 7.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.3 2.0 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.3 1.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.3 3.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.3 5.5 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.3 1.1 GO:1902477 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.3 2.1 GO:0098881 synaptic vesicle docking(GO:0016081) exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.3 1.8 GO:1901098 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) positive regulation of autophagosome maturation(GO:1901098)
0.3 3.9 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.3 2.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.3 0.3 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.2 6.0 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.2 4.6 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.2 1.6 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.2 1.3 GO:0002461 complement receptor mediated signaling pathway(GO:0002430) tolerance induction dependent upon immune response(GO:0002461)
0.2 0.9 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.2 2.2 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.2 2.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 3.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 3.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 1.6 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.2 1.1 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 2.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.2 2.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 1.0 GO:0048861 histone H3-K27 acetylation(GO:0043974) leukemia inhibitory factor signaling pathway(GO:0048861) regulation of histone H3-K27 acetylation(GO:1901674)
0.2 0.7 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.2 1.0 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.2 0.3 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.2 1.6 GO:0032486 Rap protein signal transduction(GO:0032486)
0.2 0.3 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.2 0.6 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.2 1.2 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.2 5.0 GO:0071625 vocalization behavior(GO:0071625)
0.1 1.9 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.1 3.6 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.1 1.1 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 2.2 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.3 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 1.7 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 4.2 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 6.0 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.1 2.7 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.4 GO:0009838 abscission(GO:0009838)
0.1 0.3 GO:0072276 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 1.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 3.2 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 1.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 2.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.9 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.7 GO:0051036 regulation of endosome size(GO:0051036) receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.3 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.1 0.5 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.1 0.5 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
0.1 0.3 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 4.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 1.9 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 0.5 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.1 1.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.2 GO:2000851 positive regulation of glucocorticoid secretion(GO:2000851)
0.1 0.4 GO:0006538 glutamate catabolic process(GO:0006538)
0.1 2.4 GO:0030224 monocyte differentiation(GO:0030224)
0.1 0.5 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.1 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.9 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 23.0 GO:0043434 response to peptide hormone(GO:0043434)
0.1 0.8 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.1 0.9 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.6 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 0.5 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 5.9 GO:0032091 negative regulation of protein binding(GO:0032091)
0.1 2.1 GO:0050892 intestinal absorption(GO:0050892)
0.1 2.2 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 0.1 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.1 5.8 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.1 5.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 1.1 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 1.0 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 4.2 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.2 GO:1903121 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.6 GO:0002634 regulation of germinal center formation(GO:0002634)
0.1 0.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 1.8 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.0 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 1.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.0 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 3.6 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 3.6 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 3.1 GO:0007586 digestion(GO:0007586)
0.0 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 1.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:1901909 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 1.7 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.3 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.0 0.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.8 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 1.1 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 1.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.8 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 1.1 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.8 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0033198 response to ATP(GO:0033198)
0.0 0.1 GO:2001179 interleukin-10 secretion(GO:0072608) regulation of interleukin-10 secretion(GO:2001179)
0.0 0.3 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 1.3 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0030049 muscle filament sliding(GO:0030049)
0.0 0.9 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.6 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 0.0 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.0 0.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
1.1 14.8 GO:0097418 neurofibrillary tangle(GO:0097418)
1.0 9.6 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.9 4.7 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.9 6.6 GO:0005927 muscle tendon junction(GO:0005927)
0.8 2.4 GO:0044753 amphisome(GO:0044753)
0.6 3.4 GO:0097513 myosin II filament(GO:0097513)
0.5 8.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.5 2.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.4 3.1 GO:0005827 polar microtubule(GO:0005827)
0.4 5.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.4 4.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.3 5.9 GO:0005916 fascia adherens(GO:0005916)
0.3 2.0 GO:0031673 H zone(GO:0031673)
0.3 3.2 GO:0070545 PeBoW complex(GO:0070545)
0.3 1.1 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.3 3.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 0.7 GO:0098842 postsynaptic early endosome(GO:0098842)
0.2 1.1 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.2 3.3 GO:0031105 septin complex(GO:0031105)
0.2 1.8 GO:0042587 glycogen granule(GO:0042587)
0.2 2.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 4.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 1.8 GO:0044754 autolysosome(GO:0044754)
0.1 6.4 GO:0035861 site of double-strand break(GO:0035861)
0.1 11.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 4.7 GO:0043034 costamere(GO:0043034)
0.1 1.5 GO:0044294 dendritic growth cone(GO:0044294)
0.1 2.0 GO:0031045 dense core granule(GO:0031045)
0.1 1.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 10.8 GO:0000502 proteasome complex(GO:0000502)
0.1 2.0 GO:0031143 pseudopodium(GO:0031143)
0.1 3.3 GO:0045095 keratin filament(GO:0045095)
0.1 0.8 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.9 GO:0000801 central element(GO:0000801)
0.1 0.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 8.0 GO:0005811 lipid particle(GO:0005811)
0.1 6.4 GO:0030315 T-tubule(GO:0030315)
0.1 3.9 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.8 GO:0042629 mast cell granule(GO:0042629)
0.1 1.0 GO:1990635 proximal dendrite(GO:1990635)
0.1 4.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 3.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 3.5 GO:0005776 autophagosome(GO:0005776)
0.0 2.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 4.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.5 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 1.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 4.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 1.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 6.0 GO:0001650 fibrillar center(GO:0001650)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.9 GO:0032420 stereocilium(GO:0032420)
0.0 6.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.5 GO:0005604 basement membrane(GO:0005604)
0.0 2.1 GO:0005903 brush border(GO:0005903)
0.0 2.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.0 GO:0005871 kinesin complex(GO:0005871)
0.0 2.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 12.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 3.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 1.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 3.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 3.2 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.7 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
3.2 12.7 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
2.1 6.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.6 6.4 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
1.3 7.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.3 3.9 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
1.1 3.4 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
1.1 7.6 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.1 3.2 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.9 3.6 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.9 5.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.8 2.3 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.7 2.2 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.7 2.9 GO:1990254 keratin filament binding(GO:1990254)
0.7 3.6 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.7 6.4 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.6 2.5 GO:0003998 acylphosphatase activity(GO:0003998)
0.6 14.8 GO:0051787 misfolded protein binding(GO:0051787)
0.6 3.7 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.6 1.7 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.5 1.6 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.5 3.6 GO:0038132 neuregulin binding(GO:0038132)
0.5 2.0 GO:0042806 fucose binding(GO:0042806)
0.4 10.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 2.0 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.4 2.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.4 1.9 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.4 5.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.4 4.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 2.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.3 3.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 2.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.3 4.3 GO:0044548 S100 protein binding(GO:0044548)
0.3 0.9 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.3 1.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.3 6.9 GO:0017081 chloride channel regulator activity(GO:0017081)
0.3 4.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.3 38.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 1.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.2 2.4 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.2 2.6 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.2 4.7 GO:0031005 filamin binding(GO:0031005)
0.2 3.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 7.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 1.3 GO:0004875 complement receptor activity(GO:0004875)
0.2 0.9 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 1.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 2.0 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.2 3.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 5.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 3.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 0.7 GO:1903135 cupric ion binding(GO:1903135)
0.2 3.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 2.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.2 1.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 4.2 GO:0004602 glutathione peroxidase activity(GO:0004602) glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 4.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 0.5 GO:0051381 histamine binding(GO:0051381)
0.1 1.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.5 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 1.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 2.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 5.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 11.4 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.9 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 3.1 GO:0043236 laminin binding(GO:0043236)
0.1 0.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 2.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 1.0 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 3.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.7 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.1 0.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 2.1 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.4 GO:0070728 leucine binding(GO:0070728)
0.1 0.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 1.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 4.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 4.0 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 2.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.8 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 2.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 6.5 GO:0031072 heat shock protein binding(GO:0031072)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 5.2 GO:0000149 SNARE binding(GO:0000149)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 2.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 2.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 2.3 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 1.8 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 0.2 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 3.2 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.0 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 2.1 GO:0002039 p53 binding(GO:0002039)
0.0 1.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 8.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 2.4 GO:0005262 calcium channel activity(GO:0005262)
0.0 2.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 9.4 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 2.7 GO:0008083 growth factor activity(GO:0008083)
0.0 6.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 5.4 GO:0004175 endopeptidase activity(GO:0004175)
0.0 1.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.7 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 2.5 GO:0051015 actin filament binding(GO:0051015)
0.0 2.9 GO:0048037 cofactor binding(GO:0048037)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.3 14.7 PID ARF6 PATHWAY Arf6 signaling events
0.2 4.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 19.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.2 11.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 7.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 13.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.2 4.5 PID ARF 3PATHWAY Arf1 pathway
0.2 4.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 2.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 2.9 PID CONE PATHWAY Visual signal transduction: Cones
0.1 2.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 4.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.8 7.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.6 8.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.5 5.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.4 15.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.3 2.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.3 4.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 3.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 3.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 5.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 3.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 6.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 2.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 2.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 3.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 3.7 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 1.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 3.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 3.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 2.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 6.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 9.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 9.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 3.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 2.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 3.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.2 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 4.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.6 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 1.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.9 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha