ISMARA results: Lhx2

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GSE58827: Dynamics of the Mouse Liver

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Results for Lhx2_Hoxc5

Z-value: 1.10

Motif logo

Transcription factors associated with Lhx2_Hoxc5

Gene Symbol	Gene ID	Gene Info
Lhx2 Ensembl NCBI MGI UniProt	ENSMUSG00000000247.5	LIM homeobox protein 2
Hoxc5 Ensembl NCBI MGI UniProt	ENSMUSG00000022485.3	homeobox C5

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Lhx2	mm10_v2_chr2_+_38339258_38339281	-0.79	1.3e-08	Click!
Hoxc5	mm10_v2_chr15_+_103013815_103013815	-0.45	5.8e-03	Click!

Activity profile of Lhx2_Hoxc5 motif

Sorted Z-values of Lhx2_Hoxc5 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr12_+_104338372 Show fit	10.56	ENSMUST00000101078.5 ENSMUST00000043058.3	Serpina3m Ensembl NCBI MGI UniProt Show fit Serpina3k Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade A, member 3M serine (or cysteine) peptidase inhibitor, clade A, member 3K
chr5_-_87254804 Show fit	8.01	ENSMUST00000075858.3	Ugt2b37 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide B37
chr7_-_14492926 Show fit	7.73	ENSMUST00000108524.3	Sult2a7 Ensembl NCBI MGI UniProt Show fit	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 7
chr4_-_61674094 Show fit	7.71	ENSMUST00000098040.3	Mup18 Ensembl NCBI MGI UniProt Show fit	major urinary protein 18
chr4_-_60499332 Show fit	7.66	ENSMUST00000135953.1	Mup1 Ensembl NCBI MGI UniProt Show fit	major urinary protein 1
chr4_-_60222580 Show fit	6.84	ENSMUST00000095058.4 ENSMUST00000163931.1	Mup8 Ensembl NCBI MGI UniProt Show fit	major urinary protein 8
chr4_-_60582152 Show fit	6.46	ENSMUST00000098047.2	Mup10 Ensembl NCBI MGI UniProt Show fit	major urinary protein 10
chr4_-_60421933 Show fit	6.17	ENSMUST00000107506.2 ENSMUST00000122381.1 ENSMUST00000118759.1 ENSMUST00000122177.1	Mup9 Ensembl NCBI MGI UniProt Show fit	major urinary protein 9
chr3_+_63295815 Show fit	6.16	ENSMUST00000029400.1	Mme Ensembl NCBI MGI UniProt Show fit	membrane metallo endopeptidase
chr3_+_138374121 Show fit	6.08	ENSMUST00000171054.1	Adh6-ps1 Ensembl NCBI MGI UniProt Show fit	alcohol dehydrogenase 6 (class V), pseudogene 1
chr4_-_60662358 Show fit	5.98	ENSMUST00000084544.4 ENSMUST00000098046.3	Mup11 Ensembl NCBI MGI UniProt Show fit	major urinary protein 11
chrM_+_10167 Show fit	5.94	ENSMUST00000082414.1	mt-Nd4 Ensembl NCBI MGI UniProt Show fit	mitochondrially encoded NADH dehydrogenase 4
chr4_-_60139857 Show fit	5.67	ENSMUST00000107490.4 ENSMUST00000074700.2	Mup2 Ensembl NCBI MGI UniProt Show fit	major urinary protein 2
chr19_-_39649046 Show fit	5.50	ENSMUST00000067328.6	Cyp2c67 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 2, subfamily c, polypeptide 67
chr13_+_4434306 Show fit	5.01	ENSMUST00000021630.8	Akr1c6 Ensembl NCBI MGI UniProt Show fit	aldo-keto reductase family 1, member C6
chr3_-_67515487 Show fit	4.44	ENSMUST00000178314.1 ENSMUST00000054825.4	Rarres1 Ensembl NCBI MGI UniProt Show fit	retinoic acid receptor responder (tazarotene induced) 1
chr5_+_29195983 Show fit	4.18	ENSMUST00000160888.1 ENSMUST00000159272.1 ENSMUST00000001247.5 ENSMUST00000161398.1 ENSMUST00000160246.1	Rnf32 Ensembl NCBI MGI UniProt Show fit	ring finger protein 32
chr8_+_46010596 Show fit	4.16	ENSMUST00000110381.2	Lrp2bp Ensembl NCBI MGI UniProt Show fit	Lrp2 binding protein
chrM_+_9870 Show fit	4.06	ENSMUST00000084013.1	mt-Nd4l Ensembl NCBI MGI UniProt Show fit	mitochondrially encoded NADH dehydrogenase 4L
chr2_-_155074447 Show fit	3.72	ENSMUST00000137242.1 ENSMUST00000054607.9	Ahcy Ensembl NCBI MGI UniProt Show fit	S-adenosylhomocysteine hydrolase
chr5_+_137981512 Show fit	3.65	ENSMUST00000035390.5	Azgp1 Ensembl NCBI MGI UniProt Show fit	alpha-2-glycoprotein 1, zinc
chr5_-_87424201 Show fit	3.55	ENSMUST00000072818.5	Ugt2b38 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide B38
chr4_-_108118504 Show fit	3.46	ENSMUST00000149106.1	Scp2 Ensembl NCBI MGI UniProt Show fit	sterol carrier protein 2, liver
chr2_-_86347764 Show fit	3.45	ENSMUST00000099894.2	Olfr1055 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 1055
chr5_-_87140318 Show fit	3.44	ENSMUST00000067790.6 ENSMUST00000113327.1	Ugt2b5 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide B5
chr16_+_22918378 Show fit	3.40	ENSMUST00000170805.1	Fetub Ensembl NCBI MGI UniProt Show fit	fetuin beta
chr6_-_141946960 Show fit	3.28	ENSMUST00000042119.5	Slco1a1 Ensembl NCBI MGI UniProt Show fit	solute carrier organic anion transporter family, member 1a1
chr7_-_100656953 Show fit	3.22	ENSMUST00000107046.1 ENSMUST00000107045.1 ENSMUST00000139708.1	Plekhb1 Ensembl NCBI MGI UniProt Show fit	pleckstrin homology domain containing, family B (evectins) member 1
chr1_+_88070765 Show fit	3.20	ENSMUST00000073772.4	Ugt1a9 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 1 family, polypeptide A9
chr14_-_64455903 Show fit	3.12	ENSMUST00000067927.7	Msra Ensembl NCBI MGI UniProt Show fit	methionine sulfoxide reductase A
chr3_-_85722474 Show fit	3.10	ENSMUST00000119077.1	Fam160a1 Ensembl NCBI MGI UniProt Show fit	family with sequence similarity 160, member A1
chr1_-_24612700 Show fit	3.07	ENSMUST00000088336.1	Gm10222 Ensembl NCBI MGI UniProt Show fit	predicted gene 10222
chr7_-_119523477 Show fit	3.07	ENSMUST00000033267.2	Pdilt Ensembl NCBI MGI UniProt Show fit	protein disulfide isomerase-like, testis expressed
chr16_-_10543028 Show fit	3.06	ENSMUST00000184863.1 ENSMUST00000038281.5	Dexi Ensembl NCBI MGI UniProt Show fit	dexamethasone-induced transcript
chr3_+_60081861 Show fit	3.05	ENSMUST00000029326.5	Sucnr1 Ensembl NCBI MGI UniProt Show fit	succinate receptor 1
chr6_-_141946791 Show fit	2.97	ENSMUST00000168119.1	Slco1a1 Ensembl NCBI MGI UniProt Show fit	solute carrier organic anion transporter family, member 1a1
chr1_-_150466165 Show fit	2.77	ENSMUST00000162367.1 ENSMUST00000161611.1 ENSMUST00000161320.1 ENSMUST00000159035.1	Prg4 Ensembl NCBI MGI UniProt Show fit	proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
chr2_+_109917639 Show fit	2.70	ENSMUST00000046548.7 ENSMUST00000111037.2	Lgr4 Ensembl NCBI MGI UniProt Show fit	leucine-rich repeat-containing G protein-coupled receptor 4
chrX_+_103356464 Show fit	2.64	ENSMUST00000116547.2	Chic1 Ensembl NCBI MGI UniProt Show fit	cysteine-rich hydrophobic domain 1
chr3_+_81999461 Show fit	2.64	ENSMUST00000107736.1	Asic5 Ensembl NCBI MGI UniProt Show fit	acid-sensing (proton-gated) ion channel family member 5
chr4_+_43493345 Show fit	2.61	ENSMUST00000030181.5 ENSMUST00000107922.2	Ccdc107 Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 107
chr15_-_60921270 Show fit	2.56	ENSMUST00000096418.3	A1bg Ensembl NCBI MGI UniProt Show fit	alpha-1-B glycoprotein
chrM_+_9452 Show fit	2.56	ENSMUST00000082411.1	mt-Nd3 Ensembl NCBI MGI UniProt Show fit	mitochondrially encoded NADH dehydrogenase 3
chr11_-_113710017 Show fit	2.55	ENSMUST00000018871.1	Cpsf4l Ensembl NCBI MGI UniProt Show fit	cleavage and polyadenylation specific factor 4-like
chr9_-_15301555 Show fit	2.54	ENSMUST00000034414.8	4931406C07Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 4931406C07 gene
chr10_+_93488766 Show fit	2.51	ENSMUST00000129421.1	Hal Ensembl NCBI MGI UniProt Show fit	histidine ammonia lyase
chr13_+_67833235 Show fit	2.50	ENSMUST00000060609.7	Gm10037 Ensembl NCBI MGI UniProt Show fit	predicted gene 10037
chr5_+_87000838 Show fit	2.48	ENSMUST00000031186.7	Ugt2b35 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide B35
chr13_+_34734837 Show fit	2.43	ENSMUST00000039605.6	Fam50b Ensembl NCBI MGI UniProt Show fit	family with sequence similarity 50, member B
chr3_+_142594847 Show fit	2.43	ENSMUST00000029936.4	Gbp2b Ensembl NCBI MGI UniProt Show fit	guanylate binding protein 2b
chr15_+_4727175 Show fit	2.42	ENSMUST00000162585.1	C6 Ensembl NCBI MGI UniProt Show fit	complement component 6
chrX_-_143933089 Show fit	2.40	ENSMUST00000087313.3	Dcx Ensembl NCBI MGI UniProt Show fit	doublecortin
chr15_+_4727202 Show fit	2.35	ENSMUST00000161997.1 ENSMUST00000022788.8	C6 Ensembl NCBI MGI UniProt Show fit	complement component 6
chr2_-_5676046 Show fit	2.30	ENSMUST00000114987.3	Camk1d Ensembl NCBI MGI UniProt Show fit	calcium/calmodulin-dependent protein kinase ID
chr1_+_58113136 Show fit	2.30	ENSMUST00000040999.7	Aox3 Ensembl NCBI MGI UniProt Show fit	aldehyde oxidase 3
chr15_+_4727265 Show fit	2.28	ENSMUST00000162350.1	C6 Ensembl NCBI MGI UniProt Show fit	complement component 6
chr16_+_11406618 Show fit	2.26	ENSMUST00000122168.1	Snx29 Ensembl NCBI MGI UniProt Show fit	sorting nexin 29
chr17_-_59013264 Show fit	2.25	ENSMUST00000174122.1 ENSMUST00000025065.5	Nudt12 Ensembl NCBI MGI UniProt Show fit	nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr6_-_115592571 Show fit	2.24	ENSMUST00000112957.1	2510049J12Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 2510049J12 gene
chr18_+_37435602 Show fit	2.21	ENSMUST00000055495.5	Pcdhb12 Ensembl NCBI MGI UniProt Show fit	protocadherin beta 12
chr10_-_92375367 Show fit	2.17	ENSMUST00000182870.1	Gm20757 Ensembl NCBI MGI UniProt Show fit	predicted gene, 20757
chr14_-_68533689 Show fit	2.15	ENSMUST00000022640.7	Adam7 Ensembl NCBI MGI UniProt Show fit	a disintegrin and metallopeptidase domain 7
chr8_+_56551090 Show fit	2.09	ENSMUST00000040218.5 ENSMUST00000110322.3	Fbxo8 Ensembl NCBI MGI UniProt Show fit	F-box protein 8
chr15_-_3303521 Show fit	2.05	ENSMUST00000165386.1	Ccdc152 Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 152
chr1_+_167618246 Show fit	1.99	ENSMUST00000111380.1	Rxrg Ensembl NCBI MGI UniProt Show fit	retinoid X receptor gamma
chr10_+_63024315 Show fit	1.98	ENSMUST00000124784.1	Pbld2 Ensembl NCBI MGI UniProt Show fit	phenazine biosynthesis-like protein domain containing 2
chr5_-_87092546 Show fit	1.88	ENSMUST00000132667.1 ENSMUST00000145617.1 ENSMUST00000094649.4	Ugt2b36 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide B36
chr19_-_46672883 Show fit	1.88	ENSMUST00000026012.7	Cyp17a1 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 17, subfamily a, polypeptide 1
chr11_-_121388186 Show fit	1.85	ENSMUST00000106107.2	Rab40b Ensembl NCBI MGI UniProt Show fit	Rab40b, member RAS oncogene family
chr2_-_69712461 Show fit	1.84	ENSMUST00000102706.3 ENSMUST00000073152.6	Fastkd1 Ensembl NCBI MGI UniProt Show fit	FAST kinase domains 1
chr2_-_17460610 Show fit	1.83	ENSMUST00000145492.1	Nebl Ensembl NCBI MGI UniProt Show fit	nebulette
chr17_-_36032682 Show fit	1.77	ENSMUST00000102678.4	H2-T23 Ensembl NCBI MGI UniProt Show fit	histocompatibility 2, T region locus 23
chr10_+_80249441 Show fit	1.76	ENSMUST00000020361.6	Ndufs7 Ensembl NCBI MGI UniProt Show fit	NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr1_+_88055377 Show fit	1.75	ENSMUST00000138182.1 ENSMUST00000113142.3	Ugt1a10 Ensembl NCBI MGI UniProt Show fit	UDP glycosyltransferase 1 family, polypeptide A10
chr12_+_55303241 Show fit	1.75	ENSMUST00000184766.1 ENSMUST00000183475.1 ENSMUST00000183654.1	1110008L16Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 1110008L16 gene
chr11_-_100762928 Show fit	1.74	ENSMUST00000107360.2 ENSMUST00000055083.3	Hcrt Ensembl NCBI MGI UniProt Show fit	hypocretin
chr5_+_146079254 Show fit	1.73	ENSMUST00000035571.8	Cyp3a59 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 3, subfamily a, polypeptide 59
chr9_+_74861888 Show fit	1.72	ENSMUST00000056006.9	Onecut1 Ensembl NCBI MGI UniProt Show fit	one cut domain, family member 1
chr12_-_75735729 Show fit	1.72	ENSMUST00000021450.4	Sgpp1 Ensembl NCBI MGI UniProt Show fit	sphingosine-1-phosphate phosphatase 1
chr14_+_65970804 Show fit	1.71	ENSMUST00000138191.1	Clu Ensembl NCBI MGI UniProt Show fit	clusterin
chr7_+_51879041 Show fit	1.70	ENSMUST00000107591.2	Gas2 Ensembl NCBI MGI UniProt Show fit	growth arrest specific 2
chr9_+_72958785 Show fit	1.67	ENSMUST00000098567.2 ENSMUST00000034734.8	Dyx1c1 Ensembl NCBI MGI UniProt Show fit	dyslexia susceptibility 1 candidate 1 homolog (human)
chr12_-_79190955 Show fit	1.66	ENSMUST00000085254.6	Rdh11 Ensembl NCBI MGI UniProt Show fit	retinol dehydrogenase 11
chr19_+_12695783 Show fit	1.65	ENSMUST00000025598.3 ENSMUST00000138545.1 ENSMUST00000154822.1	Keg1 Ensembl NCBI MGI UniProt Show fit	kidney expressed gene 1
chr9_+_80165079 Show fit	1.64	ENSMUST00000184480.1	Myo6 Ensembl NCBI MGI UniProt Show fit	myosin VI
chr4_+_147492417 Show fit	1.62	ENSMUST00000105721.2	Gm13152 Ensembl NCBI MGI UniProt Show fit	predicted gene 13152
chr7_+_132610620 Show fit	1.60	ENSMUST00000033241.5	Lhpp Ensembl NCBI MGI UniProt Show fit	phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr1_-_65186456 Show fit	1.58	ENSMUST00000169032.1	Idh1 Ensembl NCBI MGI UniProt Show fit	isocitrate dehydrogenase 1 (NADP+), soluble
chr7_-_68275098 Show fit	1.58	ENSMUST00000135564.1	Gm16157 Ensembl NCBI MGI UniProt Show fit	predicted gene 16157
chr4_+_115600975 Show fit	1.58	ENSMUST00000084342.5	Cyp4a32 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 4, subfamily a, polypeptide 32
chr1_+_177729814 Show fit	1.57	ENSMUST00000016106.5	1700016C15Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 1700016C15 gene
chr11_-_80377975 Show fit	1.56	ENSMUST00000179332.1 ENSMUST00000103225.4 ENSMUST00000134274.1	5730455P16Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 5730455P16 gene
chr18_-_56572888 Show fit	1.55	ENSMUST00000174518.1	Aldh7a1 Ensembl NCBI MGI UniProt Show fit	aldehyde dehydrogenase family 7, member A1
chr12_-_85824506 Show fit	1.55	ENSMUST00000021676.5 ENSMUST00000142331.1	0610007P14Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 0610007P14 gene
chr3_-_96452306 Show fit	1.52	ENSMUST00000093126.4 ENSMUST00000098841.3	BC107364 Ensembl NCBI MGI UniProt Show fit	cDNA sequence BC107364
chr11_+_58171648 Show fit	1.52	ENSMUST00000020820.1	Mrpl22 Ensembl NCBI MGI UniProt Show fit	mitochondrial ribosomal protein L22
chr1_+_88055467 Show fit	1.51	ENSMUST00000173325.1	Ugt1a10 Ensembl NCBI MGI UniProt Show fit	UDP glycosyltransferase 1 family, polypeptide A10
chrX_+_160768013 Show fit	1.48	ENSMUST00000033650.7	Rs1 Ensembl NCBI MGI UniProt Show fit	retinoschisis (X-linked, juvenile) 1 (human)
chr5_-_106926245 Show fit	1.47	ENSMUST00000117588.1	Hfm1 Ensembl NCBI MGI UniProt Show fit	HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr14_+_65970610 Show fit	1.46	ENSMUST00000127387.1	Clu Ensembl NCBI MGI UniProt Show fit	clusterin
chr19_-_39812744 Show fit	1.45	ENSMUST00000162507.1 ENSMUST00000160476.1	Cyp2c40 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 2, subfamily c, polypeptide 40
chr6_+_116650674 Show fit	1.43	ENSMUST00000067354.5 ENSMUST00000178241.1	8430408G22Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 8430408G22 gene
chr2_-_130424673 Show fit	1.43	ENSMUST00000110277.1	Pced1a Ensembl NCBI MGI UniProt Show fit	PC-esterase domain containing 1A
chr4_+_145670685 Show fit	1.42	ENSMUST00000105738.2	Gm13242 Ensembl NCBI MGI UniProt Show fit	predicted gene 13242
chr7_-_12998172 Show fit	1.40	ENSMUST00000120903.1	Slc27a5 Ensembl NCBI MGI UniProt Show fit	solute carrier family 27 (fatty acid transporter), member 5
chrM_-_14060 Show fit	1.40	ENSMUST00000082419.1	mt-Nd6 Ensembl NCBI MGI UniProt Show fit	mitochondrially encoded NADH dehydrogenase 6
chr3_-_157925056 Show fit	1.38	ENSMUST00000118539.1	Cth Ensembl NCBI MGI UniProt Show fit	cystathionase (cystathionine gamma-lyase)
chr16_+_88728828 Show fit	1.38	ENSMUST00000060494.6	Krtap13-1 Ensembl NCBI MGI UniProt Show fit	keratin associated protein 13-1
chr3_+_89459118 Show fit	1.37	ENSMUST00000029564.5	Pmvk Ensembl NCBI MGI UniProt Show fit	phosphomevalonate kinase
chr12_-_98577940 Show fit	1.37	ENSMUST00000110113.1	Kcnk10 Ensembl NCBI MGI UniProt Show fit	potassium channel, subfamily K, member 10
chr4_-_14621669 Show fit	1.36	ENSMUST00000143105.1	Slc26a7 Ensembl NCBI MGI UniProt Show fit	solute carrier family 26, member 7
chr12_+_116275386 Show fit	1.36	ENSMUST00000090195.4	Gm11027 Ensembl NCBI MGI UniProt Show fit	predicted gene 11027
chr9_-_16378231 Show fit	1.36	ENSMUST00000082170.5	Fat3 Ensembl NCBI MGI UniProt Show fit	FAT tumor suppressor homolog 3 (Drosophila)
chrX_-_8193387 Show fit	1.35	ENSMUST00000143223.1 ENSMUST00000033509.8	Ebp Ensembl NCBI MGI UniProt Show fit	phenylalkylamine Ca2+ antagonist (emopamil) binding protein
chrX_+_57212110 Show fit	1.32	ENSMUST00000033466.1	Cd40lg Ensembl NCBI MGI UniProt Show fit	CD40 ligand
chr1_-_187215454 Show fit	1.32	ENSMUST00000183819.1	Spata17 Ensembl NCBI MGI UniProt Show fit	spermatogenesis associated 17
chr10_-_8886033 Show fit	1.32	ENSMUST00000015449.5	Sash1 Ensembl NCBI MGI UniProt Show fit	SAM and SH3 domain containing 1
chr7_+_51880312 Show fit	1.32	ENSMUST00000145049.1	Gas2 Ensembl NCBI MGI UniProt Show fit	growth arrest specific 2
chrM_+_8600 Show fit	1.32	ENSMUST00000082409.1	mt-Co3 Ensembl NCBI MGI UniProt Show fit	mitochondrially encoded cytochrome c oxidase III
chr2_-_35100677 Show fit	1.31	ENSMUST00000045776.4 ENSMUST00000113050.3	AI182371 Ensembl NCBI MGI UniProt Show fit	expressed sequence AI182371
chr8_-_123236198 Show fit	1.30	ENSMUST00000166768.1 ENSMUST00000098327.1	Spata2l Ensembl NCBI MGI UniProt Show fit	spermatogenesis associated 2-like
chr2_-_132247747 Show fit	1.29	ENSMUST00000110163.1 ENSMUST00000180286.1 ENSMUST00000028816.2	Tmem230 Ensembl NCBI MGI UniProt Show fit	transmembrane protein 230
chrM_+_2743 Show fit	1.29	ENSMUST00000082392.1	mt-Nd1 Ensembl NCBI MGI UniProt Show fit	mitochondrially encoded NADH dehydrogenase 1
chr2_+_152669461 Show fit	1.29	ENSMUST00000125366.1 ENSMUST00000109825.1 ENSMUST00000089059.2 ENSMUST00000079247.3	H13 Ensembl NCBI MGI UniProt Show fit	histocompatibility 13
chr4_+_95557494 Show fit	1.28	ENSMUST00000079223.4 ENSMUST00000177394.1	Fggy Ensembl NCBI MGI UniProt Show fit	FGGY carbohydrate kinase domain containing
chr5_-_3647806 Show fit	1.27	ENSMUST00000119783.1 ENSMUST00000007559.8	Gatad1 Ensembl NCBI MGI UniProt Show fit	GATA zinc finger domain containing 1
chr6_+_124304646 Show fit	1.24	ENSMUST00000112541.2 ENSMUST00000032234.2	Cd163 Ensembl NCBI MGI UniProt Show fit	CD163 antigen
chr12_+_16653470 Show fit	1.23	ENSMUST00000111064.1	Ntsr2 Ensembl NCBI MGI UniProt Show fit	neurotensin receptor 2
chr7_-_24724237 Show fit	1.22	ENSMUST00000081657.4	Gm4763 Ensembl NCBI MGI UniProt Show fit	predicted gene 4763
chr13_-_81710937 Show fit	1.20	ENSMUST00000161920.1 ENSMUST00000048993.5	Polr3g Ensembl NCBI MGI UniProt Show fit	polymerase (RNA) III (DNA directed) polypeptide G
chrM_+_7005 Show fit	1.20	ENSMUST00000082405.1	mt-Co2 Ensembl NCBI MGI UniProt Show fit	mitochondrially encoded cytochrome c oxidase II
chrX_+_16619698 Show fit	1.20	ENSMUST00000026013.5	Maoa Ensembl NCBI MGI UniProt Show fit	monoamine oxidase A
chr7_-_140154712 Show fit	1.19	ENSMUST00000059241.7	Sprn Ensembl NCBI MGI UniProt Show fit	shadow of prion protein
chrX_+_170009892 Show fit	1.18	ENSMUST00000180251.1	Gm21887 Ensembl NCBI MGI UniProt Show fit	predicted gene, 21887
chr1_-_175979114 Show fit	1.17	ENSMUST00000104983.1	B020018G12Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA B020018G12 gene
chr2_-_62412219 Show fit	1.17	ENSMUST00000047812.7	Dpp4 Ensembl NCBI MGI UniProt Show fit	dipeptidylpeptidase 4
chr15_-_67113909 Show fit	1.17	ENSMUST00000092640.5	St3gal1 Ensembl NCBI MGI UniProt Show fit	ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr6_+_134640940 Show fit	1.16	ENSMUST00000062755.8	Loh12cr1 Ensembl NCBI MGI UniProt Show fit	loss of heterozygosity, 12, chromosomal region 1 homolog (human)
chr8_+_72219726 Show fit	1.16	ENSMUST00000003123.8	Fam32a Ensembl NCBI MGI UniProt Show fit	family with sequence similarity 32, member A
chr16_-_35363842 Show fit	1.15	ENSMUST00000043521.4	Sec22a Ensembl NCBI MGI UniProt Show fit	SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
chrX_-_143933204 Show fit	1.15	ENSMUST00000112851.1 ENSMUST00000112856.2 ENSMUST00000033642.3	Dcx Ensembl NCBI MGI UniProt Show fit	doublecortin
chr3_+_94372794 Show fit	1.15	ENSMUST00000029795.3	Rorc Ensembl NCBI MGI UniProt Show fit	RAR-related orphan receptor gamma
chr4_+_47208005 Show fit	1.15	ENSMUST00000082303.6 ENSMUST00000102917.4	Col15a1 Ensembl NCBI MGI UniProt Show fit	collagen, type XV, alpha 1
chr1_-_153851189 Show fit	1.14	ENSMUST00000059607.6	5830403L16Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 5830403L16 gene
chr10_+_29143996 Show fit	1.14	ENSMUST00000092629.2	Soga3 Ensembl NCBI MGI UniProt Show fit	SOGA family member 3
chr6_-_85762480 Show fit	1.13	ENSMUST00000168531.1	Cml3 Ensembl NCBI MGI UniProt Show fit	camello-like 3
chr2_-_164638789 Show fit	1.13	ENSMUST00000109336.1	Wfdc16 Ensembl NCBI MGI UniProt Show fit	WAP four-disulfide core domain 16
chr7_+_130774069 Show fit	1.13	ENSMUST00000048453.5	Btbd16 Ensembl NCBI MGI UniProt Show fit	BTB (POZ) domain containing 16
chr16_+_44867097 Show fit	1.13	ENSMUST00000102805.3	Cd200r2 Ensembl NCBI MGI UniProt Show fit	Cd200 receptor 2
chr2_+_91257323 Show fit	1.12	ENSMUST00000111349.2 ENSMUST00000131711.1	Pacsin3 Ensembl NCBI MGI UniProt Show fit	protein kinase C and casein kinase substrate in neurons 3
chr17_+_26715644 Show fit	1.12	ENSMUST00000062519.7 ENSMUST00000144221.1 ENSMUST00000142539.1 ENSMUST00000151681.1	Crebrf Ensembl NCBI MGI UniProt Show fit	CREB3 regulatory factor
chr12_+_111039334 Show fit	1.11	ENSMUST00000084968.7	Rcor1 Ensembl NCBI MGI UniProt Show fit	REST corepressor 1
chr4_+_102589687 Show fit	1.11	ENSMUST00000097949.4 ENSMUST00000106901.1	Pde4b Ensembl NCBI MGI UniProt Show fit	phosphodiesterase 4B, cAMP specific
chr11_+_116843278 Show fit	1.11	ENSMUST00000106370.3	Mettl23 Ensembl NCBI MGI UniProt Show fit	methyltransferase like 23
chr18_+_12741324 Show fit	1.10	ENSMUST00000115857.2 ENSMUST00000121018.1 ENSMUST00000119108.1	Cabyr Ensembl NCBI MGI UniProt Show fit	calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)
chrX_-_139782353 Show fit	1.10	ENSMUST00000101217.3	Ripply1 Ensembl NCBI MGI UniProt Show fit	ripply1 homolog (zebrafish)
chr11_-_106612928 Show fit	1.10	ENSMUST00000042780.7	Tex2 Ensembl NCBI MGI UniProt Show fit	testis expressed gene 2
chr7_-_5413145 Show fit	1.09	ENSMUST00000108569.2	Vmn1r58 Ensembl NCBI MGI UniProt Show fit	vomeronasal 1 receptor 58
chr4_-_129227883 Show fit	1.09	ENSMUST00000106051.1	C77080 Ensembl NCBI MGI UniProt Show fit	expressed sequence C77080
chrY_+_80135210 Show fit	1.08	ENSMUST00000179811.1	Gm21760 Ensembl NCBI MGI UniProt Show fit	predicted gene, 21760
chr14_-_50681645 Show fit	1.08	ENSMUST00000078075.4	Olfr747 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 747
chr16_+_18836573 Show fit	1.07	ENSMUST00000055413.6	2510002D24Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 2510002D24 gene
chr5_-_4104654 Show fit	1.07	ENSMUST00000001507.4	Cyp51 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 51
chr2_+_68104671 Show fit	1.06	ENSMUST00000042456.3	B3galt1 Ensembl NCBI MGI UniProt Show fit	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr11_-_115419917 Show fit	1.06	ENSMUST00000106537.1 ENSMUST00000043931.2 ENSMUST00000073791.3	Atp5h Ensembl NCBI MGI UniProt Show fit	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d
chr9_-_97369958 Show fit	1.05	ENSMUST00000035026.4	Trim42 Ensembl NCBI MGI UniProt Show fit	tripartite motif-containing 42
chr2_+_32606946 Show fit	1.04	ENSMUST00000113290.1	St6galnac6 Ensembl NCBI MGI UniProt Show fit	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr19_-_7802578 Show fit	1.04	ENSMUST00000120522.1 ENSMUST00000065634.7	Slc22a26 Ensembl NCBI MGI UniProt Show fit	solute carrier family 22 (organic cation transporter), member 26
chr2_+_32606979 Show fit	1.03	ENSMUST00000113289.1 ENSMUST00000095044.3	St6galnac6 Ensembl NCBI MGI UniProt Show fit	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr3_-_113577743 Show fit	1.02	ENSMUST00000067980.5	Amy1 Ensembl NCBI MGI UniProt Show fit	amylase 1, salivary
chr1_+_88306731 Show fit	1.02	ENSMUST00000040210.7	Trpm8 Ensembl NCBI MGI UniProt Show fit	transient receptor potential cation channel, subfamily M, member 8
chr14_-_66124482 Show fit	1.02	ENSMUST00000070515.1	Ephx2 Ensembl NCBI MGI UniProt Show fit	epoxide hydrolase 2, cytoplasmic
chrM_+_5319 Show fit	1.01	ENSMUST00000082402.1	mt-Co1 Ensembl NCBI MGI UniProt Show fit	mitochondrially encoded cytochrome c oxidase I
chr10_-_77166545 Show fit	1.01	ENSMUST00000081654.6	Col18a1 Ensembl NCBI MGI UniProt Show fit	collagen, type XVIII, alpha 1
chrM_+_14138 Show fit	1.00	ENSMUST00000082421.1	mt-Cytb Ensembl NCBI MGI UniProt Show fit	mitochondrially encoded cytochrome b
chr19_+_24875679 Show fit	1.00	ENSMUST00000073080.5	Gm10053 Ensembl NCBI MGI UniProt Show fit	predicted gene 10053
chr10_-_81407641 Show fit	1.00	ENSMUST00000140916.1	Nfic Ensembl NCBI MGI UniProt Show fit	nuclear factor I/C
chr11_+_101665541 Show fit	0.99	ENSMUST00000039388.2	Arl4d Ensembl NCBI MGI UniProt Show fit	ADP-ribosylation factor-like 4D
chrX_-_60893430 Show fit	0.99	ENSMUST00000135107.2	Sox3 Ensembl NCBI MGI UniProt Show fit	SRY-box containing gene 3
chr13_+_4191163 Show fit	0.99	ENSMUST00000021634.2	Akr1c13 Ensembl NCBI MGI UniProt Show fit	aldo-keto reductase family 1, member C13
chr12_+_8771317 Show fit	0.98	ENSMUST00000020911.7	Sdc1 Ensembl NCBI MGI UniProt Show fit	syndecan 1
chr9_+_57697612 Show fit	0.97	ENSMUST00000034865.4	Cyp1a1 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 1, subfamily a, polypeptide 1
chr19_-_44107447 Show fit	0.97	ENSMUST00000119591.1 ENSMUST00000026217.4	Chuk Ensembl NCBI MGI UniProt Show fit	conserved helix-loop-helix ubiquitous kinase
chr7_+_24270420 Show fit	0.97	ENSMUST00000108438.3	Zfp93 Ensembl NCBI MGI UniProt Show fit	zinc finger protein 93
chr3_-_92827239 Show fit	0.96	ENSMUST00000072363.4	Kprp Ensembl NCBI MGI UniProt Show fit	keratinocyte expressed, proline-rich
chr11_+_114675431 Show fit	0.96	ENSMUST00000045779.5	Ttyh2 Ensembl NCBI MGI UniProt Show fit	tweety homolog 2 (Drosophila)
chr2_+_103566304 Show fit	0.96	ENSMUST00000076212.3	Abtb2 Ensembl NCBI MGI UniProt Show fit	ankyrin repeat and BTB (POZ) domain containing 2
chr1_+_16688405 Show fit	0.95	ENSMUST00000026881.4	Ly96 Ensembl NCBI MGI UniProt Show fit	lymphocyte antigen 96
chr19_-_19001099 Show fit	0.94	ENSMUST00000040153.8 ENSMUST00000112828.1	Rorb Ensembl NCBI MGI UniProt Show fit	RAR-related orphan receptor beta
chr12_-_84617326 Show fit	0.94	ENSMUST00000021666.4	Abcd4 Ensembl NCBI MGI UniProt Show fit	ATP-binding cassette, sub-family D (ALD), member 4
chr4_+_99030946 Show fit	0.94	ENSMUST00000030280.6	Angptl3 Ensembl NCBI MGI UniProt Show fit	angiopoietin-like 3
chr2_+_162987330 Show fit	0.93	ENSMUST00000018012.7	Sgk2 Ensembl NCBI MGI UniProt Show fit	serum/glucocorticoid regulated kinase 2
chr4_+_104913456 Show fit	0.93	ENSMUST00000106803.2 ENSMUST00000106804.1	1700024P16Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 1700024P16 gene
chr8_+_70527829 Show fit	0.93	ENSMUST00000119698.1	Fkbp8 Ensembl NCBI MGI UniProt Show fit	FK506 binding protein 8
chr19_-_41933276 Show fit	0.92	ENSMUST00000075280.4 ENSMUST00000112123.2	Exosc1 Ensembl NCBI MGI UniProt Show fit	exosome component 1
chr17_-_40319205 Show fit	0.92	ENSMUST00000026498.4	Crisp1 Ensembl NCBI MGI UniProt Show fit	cysteine-rich secretory protein 1
chr2_+_162987502 Show fit	0.91	ENSMUST00000117123.1	Sgk2 Ensembl NCBI MGI UniProt Show fit	serum/glucocorticoid regulated kinase 2
chr19_-_10830045 Show fit	0.91	ENSMUST00000080292.5	Cd6 Ensembl NCBI MGI UniProt Show fit	CD6 antigen
chrX_-_7899220 Show fit	0.90	ENSMUST00000033497.2	Pqbp1 Ensembl NCBI MGI UniProt Show fit	polyglutamine binding protein 1
chr15_-_76229492 Show fit	0.89	ENSMUST00000074834.5	Plec Ensembl NCBI MGI UniProt Show fit	plectin

Network of associatons between targets according to the STRING database.

First level regulatory network of Lhx2_Hoxc5

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	6.2	GO:0071492	cellular response to UV-A(GO:0071492)
1.7	5.0	GO:0009753	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
1.4	7.0	GO:0001970	positive regulation of activation of membrane attack complex(GO:0001970)
1.2	13.6	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.9	3.7	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
0.9	2.7	GO:0061289	cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.9	3.6	GO:0016062	adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.9	3.5	GO:0032382	positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.7	2.0	GO:0009698	phenylpropanoid metabolic process(GO:0009698)
0.6	2.3	GO:0006742	NADP catabolic process(GO:0006742)
0.5	6.5	GO:0052696	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.5	3.2	GO:1902998	regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.5	1.6	GO:0006097	glyoxylate cycle(GO:0006097)
0.5	2.5	GO:0006548	histidine catabolic process(GO:0006548)
0.5	0.5	GO:0019364	pyridine nucleotide catabolic process(GO:0019364)
0.5	1.4	GO:0019343	cysteine biosynthetic process via cystathionine(GO:0019343)
0.4	1.8	GO:2000566	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.4	1.3	GO:2001200	positive regulation of dendritic cell differentiation(GO:2001200)
0.4	1.3	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.4	1.3	GO:1904211	membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.4	1.7	GO:0006668	sphinganine-1-phosphate metabolic process(GO:0006668)
0.4	0.8	GO:0071332	cellular response to fructose stimulus(GO:0071332)
0.4	1.2	GO:0010716	negative regulation of extracellular matrix disassembly(GO:0010716)
0.4	7.2	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.4	2.9	GO:0019532	oxalate transport(GO:0019532)
0.4	1.4	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.3	2.8	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.3	1.4	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.3	1.0	GO:0048627	myoblast development(GO:0048627)
0.3	1.6	GO:0009115	xanthine catabolic process(GO:0009115)
0.3	0.9	GO:1903903	regulation of establishment of T cell polarity(GO:1903903)
0.3	1.7	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.3	0.8	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.3	2.3	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.2	0.7	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.2	0.7	GO:0019085	early viral transcription(GO:0019085)
0.2	0.7	GO:0014901	regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.2	3.5	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.2	2.5	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2	0.6	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.2	0.8	GO:1901382	chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.2	2.7	GO:0042448	progesterone metabolic process(GO:0042448)
0.2	0.6	GO:0052564	response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.2	0.6	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.2	1.0	GO:0015788	UDP-N-acetylglucosamine transport(GO:0015788)
0.2	0.4	GO:1904339	negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.2	0.9	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.2	1.1	GO:0038161	prolactin signaling pathway(GO:0038161) negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.2	4.2	GO:0035634	response to stilbenoid(GO:0035634)
0.2	5.8	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.2	3.6	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2	0.9	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.2	2.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.2	0.3	GO:0071725	response to diacyl bacterial lipopeptide(GO:0071724) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to diacyl bacterial lipopeptide(GO:0071726) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.2	1.2	GO:0042420	dopamine catabolic process(GO:0042420)
0.2	1.0	GO:0033762	response to glucagon(GO:0033762)
0.2	0.8	GO:0052695	cellular glucuronidation(GO:0052695)
0.2	0.9	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	1.9	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.1	6.6	GO:0042773	ATP synthesis coupled electron transport(GO:0042773)
0.1	1.8	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.1	0.7	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.1	0.8	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
0.1	0.7	GO:0061622	glycolytic process through glucose-1-phosphate(GO:0061622)
0.1	0.9	GO:0009235	cobalamin metabolic process(GO:0009235)
0.1	0.7	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1	3.8	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1	0.7	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.1	0.4	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.1	0.4	GO:0045726	positive regulation of integrin biosynthetic process(GO:0045726)
0.1	0.4	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.1	1.3	GO:0046549	retinal cone cell development(GO:0046549)
0.1	1.6	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.1	0.6	GO:0090168	Golgi reassembly(GO:0090168)
0.1	0.4	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
0.1	1.2	GO:0070933	histone H4 deacetylation(GO:0070933)
0.1	0.8	GO:0036438	maintenance of lens transparency(GO:0036438)
0.1	1.1	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1	1.6	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.1	0.4	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1	0.6	GO:0009946	proximal/distal axis specification(GO:0009946) specification of axis polarity(GO:0065001)
0.1	0.3	GO:0006011	UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
0.1	2.4	GO:0002438	acute inflammatory response to antigenic stimulus(GO:0002438)
0.1	1.3	GO:0072615	interleukin-17 secretion(GO:0072615)
0.1	0.6	GO:0036476	neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1	2.4	GO:0044406	adhesion of symbiont to host(GO:0044406)
0.1	1.4	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1	3.4	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
0.1	0.3	GO:1990705	intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
0.1	1.0	GO:1902741	type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1	0.6	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1	2.8	GO:0034063	stress granule assembly(GO:0034063)
0.1	1.5	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.1	1.0	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	1.7	GO:0036158	outer dynein arm assembly(GO:0036158)
0.1	1.5	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1	0.7	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1	0.4	GO:0070268	cornification(GO:0070268)
0.1	1.0	GO:0050955	thermoception(GO:0050955)
0.1	0.5	GO:1903232	melanosome assembly(GO:1903232)
0.1	0.6	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1	0.4	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.1	0.4	GO:0030026	cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1	0.6	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1	0.5	GO:1902714	negative regulation of interferon-gamma secretion(GO:1902714)
0.1	0.6	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.1	0.4	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.7	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.1	0.4	GO:1902938	regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.1	1.4	GO:0030322	stabilization of membrane potential(GO:0030322)
0.1	0.4	GO:0015855	nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.1	0.3	GO:0046462	monoacylglycerol metabolic process(GO:0046462)
0.1	0.2	GO:0015755	fructose transport(GO:0015755)
0.1	0.5	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.1	0.4	GO:1902045	regulation of Fas signaling pathway(GO:1902044) negative regulation of Fas signaling pathway(GO:1902045)
0.1	1.3	GO:0019321	pentose metabolic process(GO:0019321)
0.1	0.5	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.1	0.6	GO:0007144	female meiosis I(GO:0007144)
0.1	0.5	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.1	0.8	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.1	0.3	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.1	0.7	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.4	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.1	1.6	GO:0033194	response to hydroperoxide(GO:0033194)
0.1	0.7	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1	0.6	GO:0098967	synaptic vesicle docking(GO:0016081) exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1	0.7	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1	0.2	GO:1904753	negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
0.1	2.0	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1	1.1	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.1	1.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.1	1.7	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1	2.1	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1	0.6	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.1	0.6	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1	0.8	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1	0.4	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.1	0.4	GO:0045918	negative regulation of cytolysis(GO:0045918)
0.1	0.5	GO:1901317	regulation of sperm motility(GO:1901317)
0.1	0.3	GO:0030091	protein repair(GO:0030091)
0.1	0.3	GO:0070814	hydrogen sulfide biosynthetic process(GO:0070814)
0.1	0.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.1	0.2	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1	2.6	GO:0071385	cellular response to glucocorticoid stimulus(GO:0071385)
0.1	2.7	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.1	2.1	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1	1.0	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1	1.3	GO:0022904	respiratory electron transport chain(GO:0022904)
0.1	1.9	GO:0018345	protein palmitoylation(GO:0018345)
0.1	0.3	GO:0006083	acetate metabolic process(GO:0006083)
0.1	0.1	GO:0046619	optic placode formation involved in camera-type eye formation(GO:0046619)
0.1	0.2	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.1	0.3	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.1	1.0	GO:0097237	cellular response to toxic substance(GO:0097237)
0.1	0.3	GO:0021564	vagus nerve development(GO:0021564)
0.1	0.5	GO:0060770	epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1	0.2	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1	0.3	GO:0034372	very-low-density lipoprotein particle remodeling(GO:0034372)
0.1	0.4	GO:2000628	regulation of miRNA metabolic process(GO:2000628)
0.1	0.2	GO:0061402	positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.1	0.7	GO:0035810	positive regulation of urine volume(GO:0035810)
0.0	0.2	GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0	0.1	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0	0.2	GO:0070173	regulation of enamel mineralization(GO:0070173)
0.0	0.4	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0	0.4	GO:0035376	sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0	1.7	GO:0021904	dorsal/ventral neural tube patterning(GO:0021904)
0.0	0.2	GO:0007207	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	1.4	GO:0008206	bile acid metabolic process(GO:0008206)
0.0	0.6	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.0	0.3	GO:0097210	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0	0.3	GO:0045002	double-strand break repair via single-strand annealing(GO:0045002)
0.0	1.4	GO:0010842	retina layer formation(GO:0010842)
0.0	0.2	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0	2.4	GO:1902653	cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0	0.3	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.2	GO:0043201	response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0	0.7	GO:0097066	response to thyroid hormone(GO:0097066)
0.0	0.5	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:1903406	regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.0	1.7	GO:0031018	endocrine pancreas development(GO:0031018)
0.0	0.5	GO:0021756	striatum development(GO:0021756)
0.0	0.2	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0	0.5	GO:0021984	adenohypophysis development(GO:0021984)
0.0	0.4	GO:0009133	nucleoside diphosphate biosynthetic process(GO:0009133)
0.0	1.2	GO:0050907	detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0	1.0	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.7	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.0	0.3	GO:0009162	deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0	0.6	GO:0002227	innate immune response in mucosa(GO:0002227)
0.0	0.4	GO:2000576	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0	0.1	GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress(GO:0036003)
0.0	1.2	GO:0006953	acute-phase response(GO:0006953)
0.0	0.2	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0	10.5	GO:0043434	response to peptide hormone(GO:0043434)
0.0	0.3	GO:2001138	regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0	1.2	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.2	GO:0031000	response to caffeine(GO:0031000)
0.0	0.6	GO:0097340	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0	0.5	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.4	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.3	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.3	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.4	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	5.0	GO:0007608	sensory perception of smell(GO:0007608)
0.0	0.1	GO:0002188	translation reinitiation(GO:0002188)
0.0	0.4	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.3	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.5	GO:0032825	positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.4	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0	0.5	GO:0010960	magnesium ion homeostasis(GO:0010960)
0.0	0.4	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.0	0.3	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	3.0	GO:0035725	sodium ion transmembrane transport(GO:0035725)
0.0	0.2	GO:0050691	regulation of defense response to virus by host(GO:0050691)
0.0	1.0	GO:0006805	xenobiotic metabolic process(GO:0006805)
0.0	0.4	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.2	GO:0035280	miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0	0.2	GO:0002070	epithelial cell maturation(GO:0002070)
0.0	0.1	GO:1901994	negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0	0.2	GO:1905216	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0	0.2	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.1	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.2	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.1	GO:0032439	endosome localization(GO:0032439)
0.0	0.5	GO:0007616	long-term memory(GO:0007616)
0.0	0.2	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.0	0.2	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.0	GO:0035553	oxidative single-stranded RNA demethylation(GO:0035553)
0.0	0.4	GO:0001967	suckling behavior(GO:0001967)
0.0	0.1	GO:0015881	creatine transport(GO:0015881)
0.0	0.2	GO:0042427	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0	0.6	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.0	0.2	GO:1903204	negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0	0.1	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:0035754	B cell chemotaxis(GO:0035754)
0.0	0.4	GO:0090662	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0	0.1	GO:0000960	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0	0.3	GO:0039694	viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0	0.3	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0	0.3	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.2	GO:0015838	amino-acid betaine transport(GO:0015838)
0.0	0.3	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.1	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.8	GO:0051438	regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0	0.8	GO:0050982	detection of mechanical stimulus(GO:0050982)
0.0	0.2	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.0	0.2	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0	0.2	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.8	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.1	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.2	GO:0030539	male genitalia development(GO:0030539)
0.0	0.2	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
0.0	1.0	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0	0.3	GO:1904427	positive regulation of calcium ion transmembrane transport(GO:1904427)
0.0	0.2	GO:0046688	response to copper ion(GO:0046688)
0.0	0.2	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.7	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.1	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.5	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	0.4	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.0	GO:0021934	hindbrain tangential cell migration(GO:0021934)
0.0	0.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0032917	polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0	0.1	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.8	GO:0032411	positive regulation of transporter activity(GO:0032411)
0.0	0.3	GO:0031424	keratinization(GO:0031424)
0.0	0.3	GO:0032288	myelin assembly(GO:0032288)
0.0	0.3	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.0	0.9	GO:0007006	mitochondrial membrane organization(GO:0007006)
0.0	1.1	GO:0019722	calcium-mediated signaling(GO:0019722)
0.0	0.5	GO:0007218	neuropeptide signaling pathway(GO:0007218)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	7.0	GO:0005579	membrane attack complex(GO:0005579)
0.5	1.9	GO:0002111	BRCA2-BRAF35 complex(GO:0002111)
0.3	0.8	GO:0097637	intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.3	3.5	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2	22.8	GO:0070469	respiratory chain(GO:0070469)
0.2	3.2	GO:0097418	neurofibrillary tangle(GO:0097418)
0.2	2.4	GO:0089717	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.2	0.7	GO:0098830	presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.2	0.7	GO:0044279	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.2	3.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2	1.3	GO:0071556	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2	2.5	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.2	2.4	GO:0020005	symbiont-containing vacuole membrane(GO:0020005)
0.2	1.6	GO:0071438	invadopodium membrane(GO:0071438)
0.2	1.3	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.2	0.5	GO:0032783	ELL-EAF complex(GO:0032783)
0.2	0.7	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.2	0.5	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.1	1.8	GO:0042612	MHC class I protein complex(GO:0042612)
0.1	0.5	GO:0045251	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1	0.6	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
0.1	1.7	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.1	1.0	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1	0.8	GO:0072588	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1	2.5	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	0.4	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1	1.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.1	0.3	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1	0.4	GO:0070552	BRISC complex(GO:0070552)
0.1	0.5	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.1	1.5	GO:0035686	sperm fibrous sheath(GO:0035686)
0.1	0.5	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1	0.6	GO:0045261	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1	0.5	GO:0070695	FHF complex(GO:0070695)
0.1	0.9	GO:0031254	uropod(GO:0001931) flotillin complex(GO:0016600) cell trailing edge(GO:0031254)
0.1	4.0	GO:0016235	aggresome(GO:0016235)
0.1	0.6	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.1	0.8	GO:0000178	exosome (RNase complex)(GO:0000178)
0.1	0.6	GO:0097413	Lewy body(GO:0097413)
0.1	1.0	GO:0008385	IkappaB kinase complex(GO:0008385)
0.1	0.5	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.1	0.4	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1	3.1	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1	1.8	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.1	0.6	GO:0016272	prefoldin complex(GO:0016272)
0.1	1.3	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.1	1.5	GO:0000930	gamma-tubulin complex(GO:0000930)
0.1	0.4	GO:0005787	signal peptidase complex(GO:0005787)
0.1	0.3	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	0.8	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1	0.6	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.1	8.0	GO:0072562	blood microparticle(GO:0072562)
0.0	2.8	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.4	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.6	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	9.4	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	9.7	GO:0008021	synaptic vesicle(GO:0008021)
0.0	0.7	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.4	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.4	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.3	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	13.0	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.0	0.3	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.2	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0	1.9	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	10.9	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	0.2	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.0	1.2	GO:0031201	SNARE complex(GO:0031201)
0.0	0.4	GO:0005688	U6 snRNP(GO:0005688)
0.0	0.5	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.1	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.2	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	1.2	GO:0016592	mediator complex(GO:0016592)
0.0	0.9	GO:0001533	cornified envelope(GO:0001533)
0.0	0.2	GO:0070578	RISC-loading complex(GO:0070578)
0.0	0.2	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.2	GO:0042588	zymogen granule(GO:0042588)
0.0	0.2	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.3	GO:0032433	filopodium tip(GO:0032433)
0.0	3.0	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.3	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.0	1.1	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.3	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	1.3	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	1.2	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.2	GO:0002177	manchette(GO:0002177)
0.0	1.3	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.5	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.5	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.4	GO:0045095	keratin filament(GO:0045095)
0.0	0.3	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.4	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	1.0	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.3	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.7	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	2.6	GO:0030426	growth cone(GO:0030426)
0.0	0.6	GO:0032420	stereocilium(GO:0032420)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.2	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	17.5	GO:0005783	endoplasmic reticulum(GO:0005783)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	2.0	GO:0000139	Golgi membrane(GO:0000139)
0.0	1.0	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.2	GO:0032982	myosin filament(GO:0032982)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.6	7.7	GO:0005186	insulin-activated receptor activity(GO:0005009) pheromone activity(GO:0005186)
1.7	5.0	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
1.0	3.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.9	3.5	GO:0050632	propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.8	2.4	GO:0019002	GMP binding(GO:0019002)
0.7	26.7	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.6	17.5	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.5	3.7	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.5	1.6	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.4	1.3	GO:0019150	D-ribulokinase activity(GO:0019150)
0.4	1.7	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.4	1.6	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.4	1.6	GO:0008802	betaine-aldehyde dehydrogenase activity(GO:0008802)
0.4	2.3	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.4	2.5	GO:0016841	ammonia-lyase activity(GO:0016841)
0.3	1.7	GO:0008390	testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.3	3.7	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.3	3.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.3	1.6	GO:0016623	aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.3	2.8	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.3	1.8	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.3	1.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3	1.1	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993)
0.3	1.1	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.3	1.3	GO:0008502	melatonin receptor activity(GO:0008502)
0.2	2.0	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.2	1.7	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.2	2.1	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2	1.2	GO:0008142	oxysterol binding(GO:0008142)
0.2	0.9	GO:1903135	cupric ion binding(GO:1903135)
0.2	1.4	GO:0016453	acetyl-CoA C-acetyltransferase activity(GO:0003985) CoA-transferase activity(GO:0008410) palmitoyl-CoA oxidase activity(GO:0016401) C-acetyltransferase activity(GO:0016453)
0.2	3.6	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.2	2.0	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.2	0.8	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2	0.8	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2	1.0	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.2	2.0	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.2	2.6	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.2	0.6	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.2	1.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.2	5.8	GO:0008392	arachidonic acid epoxygenase activity(GO:0008392)
0.2	0.4	GO:0034235	GPI anchor binding(GO:0034235)
0.2	0.9	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.2	3.2	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.2	3.0	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2	1.9	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.2	0.7	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.2	2.5	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.2	1.3	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2	1.8	GO:0004526	ribonuclease P activity(GO:0004526)
0.2	0.8	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2	1.8	GO:0051378	serotonin binding(GO:0051378)
0.1	4.1	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	0.6	GO:0043758	acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1	2.2	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.1	1.4	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.1	5.2	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1	0.4	GO:0047874	dolichyldiphosphatase activity(GO:0047874)
0.1	0.7	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.1	0.9	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	3.2	GO:0051787	misfolded protein binding(GO:0051787)
0.1	0.4	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.1	0.7	GO:0034602	oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1	1.7	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.1	1.8	GO:0015245	fatty acid transporter activity(GO:0015245)
0.1	0.5	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.1	0.8	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.1	0.8	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.1	1.0	GO:0031404	chloride ion binding(GO:0031404)
0.1	0.8	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.1	1.4	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.1	2.1	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1	2.8	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.3	GO:0016608	growth hormone-releasing hormone activity(GO:0016608)
0.1	0.3	GO:0019807	aspartoacylase activity(GO:0019807)
0.1	0.4	GO:0015410	manganese-transporting ATPase activity(GO:0015410)
0.1	0.5	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221)
0.1	0.3	GO:0004771	sterol esterase activity(GO:0004771)
0.1	0.8	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1	1.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.1	0.5	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1	0.3	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.1	0.7	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	0.3	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.1	1.4	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.1	0.5	GO:0005223	intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223)
0.1	0.5	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.1	0.3	GO:0050479	glyceryl-ether monooxygenase activity(GO:0050479)
0.1	0.8	GO:0051400	BH domain binding(GO:0051400)
0.1	0.2	GO:0001156	TFIIIC-class transcription factor binding(GO:0001156)
0.1	0.7	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1	0.3	GO:0005093	Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1	0.5	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1	1.9	GO:0017081	chloride channel regulator activity(GO:0017081)
0.1	0.5	GO:0051185	coenzyme transporter activity(GO:0051185)
0.1	0.2	GO:0071568	UFM1 transferase activity(GO:0071568)
0.1	0.2	GO:0004816	asparagine-tRNA ligase activity(GO:0004816)
0.1	8.5	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	0.4	GO:0005350	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.1	0.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.1	9.5	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	1.6	GO:0000400	four-way junction DNA binding(GO:0000400)
0.1	0.3	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1	0.6	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.1	1.3	GO:0035497	cAMP response element binding(GO:0035497)
0.1	2.1	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	2.0	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.1	0.5	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
0.1	1.6	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1	0.4	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1	1.9	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	0.7	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.1	0.2	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
0.1	0.6	GO:0050544	icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544)
0.1	0.7	GO:1990405	protein antigen binding(GO:1990405)
0.1	0.8	GO:0070513	death domain binding(GO:0070513)
0.0	1.0	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0	0.4	GO:0032052	bile acid binding(GO:0032052)
0.0	0.2	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.7	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.3	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0	1.6	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.6	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.2	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.2	GO:0004510	tryptophan 5-monooxygenase activity(GO:0004510)
0.0	1.4	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	1.6	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.0	1.8	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.0	0.4	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	1.5	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	1.0	GO:0005351	sugar:proton symporter activity(GO:0005351)
0.0	0.2	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.3	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.1	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.0	1.7	GO:0004521	endoribonuclease activity(GO:0004521)
0.0	1.7	GO:0032813	tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0	0.5	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.3	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.3	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0	0.3	GO:0070569	pyrimidine ribonucleotide binding(GO:0032557) uridylyltransferase activity(GO:0070569)
0.0	0.5	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0	0.9	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.1	GO:0030519	snoRNP binding(GO:0030519)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.2	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	1.2	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.4	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.2	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	4.6	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.4	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.4	GO:0048156	tau protein binding(GO:0048156)
0.0	0.4	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.4	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.0	0.3	GO:0015248	sterol transporter activity(GO:0015248)
0.0	0.8	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0	0.2	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.0	0.7	GO:0009055	electron carrier activity(GO:0009055)
0.0	0.4	GO:0048038	quinone binding(GO:0048038)
0.0	0.2	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.5	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0052795	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	0.3	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.6	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.2	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0	0.3	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0005308	creatine transmembrane transporter activity(GO:0005308)
0.0	0.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.4	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.1	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.1	GO:0089720	caspase binding(GO:0089720)
0.0	0.3	GO:0070402	NADPH binding(GO:0070402)
0.0	0.4	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.7	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.0	0.5	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.3	GO:0001618	virus receptor activity(GO:0001618)
0.0	1.2	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	2.0	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0	0.4	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.0	0.7	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.7	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:1990715	mRNA CDS binding(GO:1990715)
0.0	0.3	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.3	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.3	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0	3.5	GO:0005516	calmodulin binding(GO:0005516)
0.0	1.2	GO:0004004	RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.3	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.9	GO:0016776	phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0	0.1	GO:0019809	spermidine binding(GO:0019809)
0.0	0.6	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.5	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.6	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	1.1	GO:0005254	chloride channel activity(GO:0005254)
0.0	0.2	GO:0035198	miRNA binding(GO:0035198)
0.0	0.6	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.2	GO:0005132	type I interferon receptor binding(GO:0005132)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	3.5	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.1	2.8	PID ARF6 PATHWAY	Arf6 signaling events
0.1	4.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	1.7	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.1	3.8	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	1.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	0.4	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	2.0	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	2.2	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	1.0	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	1.4	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.7	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	1.7	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.5	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.6	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	1.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	1.0	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.8	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.5	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	1.9	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.8	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	1.1	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.6	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.6	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.5	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.7	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.2	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.6	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.4	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	1.8	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.7	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.3	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.5	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.3	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.8	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.6	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.3	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.3	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.4	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.3	PID PTP1B PATHWAY	Signaling events mediated by PTP1B

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	4.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.3	1.0	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.2	5.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.2	7.0	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.2	1.9	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.2	5.1	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.2	2.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.2	3.0	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	1.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	3.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	1.0	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	1.4	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	1.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	2.7	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.1	1.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	1.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	1.0	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.1	1.6	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	1.0	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	0.6	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	0.6	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	3.8	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.1	0.6	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	1.1	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	4.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	1.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.5	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.6	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	1.8	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.4	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.6	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.7	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.5	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	1.4	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.5	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	1.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.5	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	1.4	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.3	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.4	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.6	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.7	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.9	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.7	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.3	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	1.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	3.4	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.3	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.7	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.6	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.3	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.5	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.6	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0	0.2	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.5	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.5	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.2	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.2	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.1	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins

Results for Lhx2_Hoxc5

Z-value: 1.10

Motif logo

Transcription factors associated with Lhx2_Hoxc5

Activity-expression correlation:

Activity profile of Lhx2_Hoxc5 motif

Sorted Z-values of Lhx2_Hoxc5 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Lhx2_Hoxc5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: