Project

GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Lhx8

Z-value: 0.88

Motif logo

logo of

Transcription factors associated with Lhx8

Gene Symbol Gene ID Gene Info
Lhx8
ENSMUSG00000096225.2 LIM homeobox protein 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Lhx8mm10_v2_chr3_-_154330543_154330576-0.212.1e-01Click!

Activity profile of Lhx8 motif

Sorted Z-values of Lhx8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_104867488 4.76 ENSMUST00000043209.9
Ces2d-ps
carboxylesterase 2D, pseudogene
chr3_+_130617448 4.69 ENSMUST00000166187.1
ENSMUST00000072271.6
Etnppl
ethanolamine phosphate phospholyase
chr1_-_130661613 4.33 ENSMUST00000027657.7
C4bp
complement component 4 binding protein
chr3_+_130617645 4.23 ENSMUST00000163620.1
Etnppl
ethanolamine phosphate phospholyase
chr13_-_66227573 4.16 ENSMUST00000167981.2
Gm10772
predicted gene 10772
chr19_+_39992424 3.78 ENSMUST00000049178.2
Cyp2c37
cytochrome P450, family 2. subfamily c, polypeptide 37
chr13_+_65512678 3.76 ENSMUST00000081471.2
Gm10139
predicted gene 10139
chr19_-_4042165 3.72 ENSMUST00000042700.9
Gstp2
glutathione S-transferase, pi 2
chr5_-_87254804 3.70 ENSMUST00000075858.3
Ugt2b37
UDP glucuronosyltransferase 2 family, polypeptide B37
chr17_+_79626669 3.68 ENSMUST00000086570.1
4921513D11Rik
RIKEN cDNA 4921513D11 gene
chr4_-_96591555 3.65 ENSMUST00000055693.8
Cyp2j9
cytochrome P450, family 2, subfamily j, polypeptide 9
chr8_-_69373383 3.23 ENSMUST00000072427.4
Gm10033
predicted gene 10033
chr8_+_45627709 2.96 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2
sorbin and SH3 domain containing 2
chr10_-_92375367 2.86 ENSMUST00000182870.1
Gm20757
predicted gene, 20757
chr9_+_119102463 2.85 ENSMUST00000140326.1
ENSMUST00000165231.1
Dlec1
deleted in lung and esophageal cancer 1
chr1_+_21240597 2.52 ENSMUST00000121676.1
Gsta3
glutathione S-transferase, alpha 3
chr1_+_21240581 2.52 ENSMUST00000027067.8
Gsta3
glutathione S-transferase, alpha 3
chr5_-_87424201 2.52 ENSMUST00000072818.5
Ugt2b38
UDP glucuronosyltransferase 2 family, polypeptide B38
chr8_-_93363676 2.41 ENSMUST00000145041.1
Ces1h
carboxylesterase 1H
chr2_-_110305730 2.41 ENSMUST00000046233.2
Bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr2_+_173153048 2.23 ENSMUST00000029017.5
Pck1
phosphoenolpyruvate carboxykinase 1, cytosolic
chr2_-_67433181 2.13 ENSMUST00000180773.1
Gm26727
predicted gene, 26727
chr1_-_72284248 2.13 ENSMUST00000097698.4
ENSMUST00000027381.6
Pecr
peroxisomal trans-2-enoyl-CoA reductase
chr2_-_52558539 2.12 ENSMUST00000102760.3
ENSMUST00000102761.2
Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
chr11_+_94284652 1.98 ENSMUST00000178891.1
Gm21885
predicted gene, 21885
chr10_-_24101951 1.94 ENSMUST00000170267.1
Taar8c
trace amine-associated receptor 8C
chr2_+_177508570 1.77 ENSMUST00000108940.2
Gm14403
predicted gene 14403
chr1_-_59161594 1.67 ENSMUST00000078874.7
ENSMUST00000066374.7
Mpp4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr13_-_66852017 1.67 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr3_+_121953213 1.67 ENSMUST00000037958.7
ENSMUST00000128366.1
Arhgap29
Rho GTPase activating protein 29
chr8_+_104831572 1.48 ENSMUST00000059449.6
Ces2b
carboxyesterase 2B
chr6_+_15185203 1.43 ENSMUST00000154448.1
Foxp2
forkhead box P2
chr3_+_19957240 1.38 ENSMUST00000108325.2
Cp
ceruloplasmin
chr8_-_41054771 1.26 ENSMUST00000093534.4
Mtus1
mitochondrial tumor suppressor 1
chr6_-_71440623 1.26 ENSMUST00000002292.8
Rmnd5a
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr5_+_90518932 1.23 ENSMUST00000113179.2
ENSMUST00000128740.1
Afm
afamin
chr17_-_90088343 1.18 ENSMUST00000173917.1
Nrxn1
neurexin I
chr10_+_58497918 1.17 ENSMUST00000036576.8
Ccdc138
coiled-coil domain containing 138
chr6_-_78378851 1.15 ENSMUST00000089667.1
ENSMUST00000167492.1
Reg3d
regenerating islet-derived 3 delta
chr15_-_99820072 1.14 ENSMUST00000109024.2
Lima1
LIM domain and actin binding 1
chr4_-_96077509 1.12 ENSMUST00000097973.2
ENSMUST00000030305.6
ENSMUST00000107078.2
Cyp2j13
cytochrome P450, family 2, subfamily j, polypeptide 13
chr10_-_4432312 1.09 ENSMUST00000126102.1
ENSMUST00000131853.1
ENSMUST00000042251.4
Rmnd1
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr10_-_4432285 1.06 ENSMUST00000155172.1
Rmnd1
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr4_+_53011916 1.06 ENSMUST00000107665.3
Nipsnap3b
nipsnap homolog 3B (C. elegans)
chr5_-_62765618 1.05 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_-_170867761 1.02 ENSMUST00000027974.6
Atf6
activating transcription factor 6
chr1_+_33908172 0.99 ENSMUST00000182513.1
ENSMUST00000183034.1
Dst
dystonin
chr4_-_62502233 0.99 ENSMUST00000037820.2
Hdhd3
haloacid dehalogenase-like hydrolase domain containing 3
chr3_-_116712696 0.98 ENSMUST00000169530.1
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr15_-_98221056 0.94 ENSMUST00000170618.1
ENSMUST00000141911.1
Olfr287
olfactory receptor 287
chr3_-_116712644 0.88 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr3_-_57692537 0.87 ENSMUST00000099091.3
Gm410
predicted gene 410
chr1_+_88306731 0.87 ENSMUST00000040210.7
Trpm8
transient receptor potential cation channel, subfamily M, member 8
chr9_+_6168601 0.85 ENSMUST00000168039.1
Pdgfd
platelet-derived growth factor, D polypeptide
chr13_+_4574075 0.83 ENSMUST00000021628.3
Akr1c21
aldo-keto reductase family 1, member C21
chr11_+_110968016 0.82 ENSMUST00000106636.1
ENSMUST00000180023.1
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr8_+_72219726 0.81 ENSMUST00000003123.8
Fam32a
family with sequence similarity 32, member A
chr6_-_40999479 0.78 ENSMUST00000166306.1
Gm2663
predicted gene 2663
chr7_-_60005101 0.76 ENSMUST00000059305.10
Snrpn
small nuclear ribonucleoprotein N
chr11_-_102579071 0.74 ENSMUST00000107080.1
Gm11627
predicted gene 11627
chr2_+_73312601 0.74 ENSMUST00000090811.4
ENSMUST00000112050.1
Scrn3
secernin 3
chr6_-_3763618 0.73 ENSMUST00000171613.1
Calcr
calcitonin receptor
chr5_+_67306941 0.71 ENSMUST00000162372.1
ENSMUST00000113676.2
Slc30a9
solute carrier family 30 (zinc transporter), member 9
chr10_-_19907545 0.69 ENSMUST00000134220.1
Pex7
peroxisomal biogenesis factor 7
chr17_+_8182247 0.68 ENSMUST00000161898.1
Fgfr1op
Fgfr1 oncogene partner
chr6_+_40964760 0.66 ENSMUST00000076638.5
1810009J06Rik
RIKEN cDNA 1810009J06 gene
chr3_+_37348645 0.66 ENSMUST00000038885.3
Fgf2
fibroblast growth factor 2
chr14_+_51411001 0.66 ENSMUST00000022438.5
ENSMUST00000163019.1
ENSMUST00000159674.1
Vmn2r88
vomeronasal 2, receptor 88
chr3_-_117077760 0.65 ENSMUST00000029642.5
1700061I17Rik
RIKEN cDNA 1700061I17 gene
chr16_-_48771956 0.64 ENSMUST00000170861.1
Trat1
T cell receptor associated transmembrane adaptor 1
chr8_+_123443288 0.64 ENSMUST00000108830.1
Def8
differentially expressed in FDCP 8
chr12_-_20900867 0.63 ENSMUST00000079237.5
Zfp125
zinc finger protein 125
chr8_+_123442969 0.62 ENSMUST00000093049.3
ENSMUST00000065534.3
ENSMUST00000001522.3
ENSMUST00000124741.1
ENSMUST00000108832.1
ENSMUST00000132063.1
ENSMUST00000128424.1
Def8
differentially expressed in FDCP 8
chr16_+_24721842 0.61 ENSMUST00000115314.2
Lpp
LIM domain containing preferred translocation partner in lipoma
chr5_-_145191566 0.59 ENSMUST00000037056.8
Atp5j2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2
chr14_+_48446340 0.53 ENSMUST00000111735.2
Tmem260
transmembrane protein 260
chr16_+_23429133 0.53 ENSMUST00000038730.6
Rtp1
receptor transporter protein 1
chr14_+_46832127 0.53 ENSMUST00000068532.8
Cgrrf1
cell growth regulator with ring finger domain 1
chr3_-_53017195 0.53 ENSMUST00000036665.4
Cog6
component of oligomeric golgi complex 6
chr13_-_62466709 0.52 ENSMUST00000076195.5
Zfp935
zinc finger protein 935
chr14_+_48446128 0.50 ENSMUST00000124720.1
Tmem260
transmembrane protein 260
chr3_-_73056943 0.49 ENSMUST00000059407.7
Slitrk3
SLIT and NTRK-like family, member 3
chr3_-_100685431 0.49 ENSMUST00000008907.7
Man1a2
mannosidase, alpha, class 1A, member 2
chr6_-_130026954 0.47 ENSMUST00000074056.2
Klra6
killer cell lectin-like receptor, subfamily A, member 6
chr1_+_107361929 0.47 ENSMUST00000027566.2
Serpinb11
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
chr8_+_110079758 0.45 ENSMUST00000058804.8
Zfp612
zinc finger protein 612
chr7_-_60005049 0.44 ENSMUST00000179360.1
Snurf
SNRPN upstream reading frame
chr14_+_60768120 0.42 ENSMUST00000025940.6
C1qtnf9
C1q and tumor necrosis factor related protein 9
chr17_+_17374332 0.41 ENSMUST00000024620.6
Riok2
RIO kinase 2 (yeast)
chr7_-_3169145 0.41 ENSMUST00000171749.1
AU018091
expressed sequence AU018091
chr5_+_137553517 0.40 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
Actl6b
actin-like 6B
chr10_+_24076500 0.40 ENSMUST00000051133.5
Taar8a
trace amine-associated receptor 8A
chr5_+_121795034 0.40 ENSMUST00000162327.1
Atxn2
ataxin 2
chr14_+_52769753 0.40 ENSMUST00000178768.2
Trav7d-4
T cell receptor alpha variable 7D-4
chr18_+_12972225 0.39 ENSMUST00000025290.5
Impact
imprinted and ancient
chr14_+_53461099 0.39 ENSMUST00000181728.1
Trav7-4
T cell receptor alpha variable 7-4
chr11_+_73350839 0.39 ENSMUST00000120137.1
Olfr20
olfactory receptor 20
chr4_-_155645408 0.36 ENSMUST00000115821.2
Gm10563
predicted gene 10563
chr5_+_123930675 0.35 ENSMUST00000094320.3
ENSMUST00000165148.1
Ccdc62
coiled-coil domain containing 62
chr18_-_7297901 0.34 ENSMUST00000081275.4
Armc4
armadillo repeat containing 4
chr2_+_21205719 0.33 ENSMUST00000054591.3
ENSMUST00000102952.1
ENSMUST00000138965.1
ENSMUST00000138914.1
ENSMUST00000102951.1
Thnsl1
threonine synthase-like 1 (bacterial)
chr5_+_87925624 0.32 ENSMUST00000113271.2
Csn3
casein kappa
chr14_+_14820765 0.31 ENSMUST00000112631.2
ENSMUST00000178538.1
ENSMUST00000112630.2
Nek10
NIMA (never in mitosis gene a)- related kinase 10
chrX_+_101640056 0.31 ENSMUST00000119299.1
ENSMUST00000044475.4
Ogt
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
chr18_-_43687695 0.30 ENSMUST00000082254.6
Jakmip2
janus kinase and microtubule interacting protein 2
chr1_+_164048214 0.30 ENSMUST00000027874.5
Sele
selectin, endothelial cell
chr1_-_44218952 0.30 ENSMUST00000054801.3
Mettl21e
methyltransferase like 21E
chr2_+_112284561 0.29 ENSMUST00000053666.7
Slc12a6
solute carrier family 12, member 6
chr18_+_23415400 0.29 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna
dystrobrevin alpha
chr11_-_102407455 0.28 ENSMUST00000107098.1
ENSMUST00000018821.2
Slc25a39
solute carrier family 25, member 39
chr15_+_101115738 0.28 ENSMUST00000070875.6
Ankrd33
ankyrin repeat domain 33
chr4_-_34050077 0.28 ENSMUST00000029927.5
Spaca1
sperm acrosome associated 1
chrY_-_2663658 0.27 ENSMUST00000091178.1
Sry
sex determining region of Chr Y
chr4_-_118489755 0.26 ENSMUST00000184261.1
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr2_-_89024099 0.25 ENSMUST00000099799.2
Olfr1217
olfactory receptor 1217
chr15_+_78935177 0.25 ENSMUST00000145157.1
ENSMUST00000123013.1
Nol12
nucleolar protein 12
chr11_-_102579461 0.25 ENSMUST00000107081.1
Gm11627
predicted gene 11627
chr11_-_75937677 0.24 ENSMUST00000108420.2
Rph3al
rabphilin 3A-like (without C2 domains)
chr4_-_136898803 0.24 ENSMUST00000046285.5
C1qa
complement component 1, q subcomponent, alpha polypeptide
chr6_+_11926758 0.24 ENSMUST00000133776.1
Phf14
PHD finger protein 14
chr3_-_83049797 0.23 ENSMUST00000048246.3
Fgb
fibrinogen beta chain
chr9_+_58129476 0.21 ENSMUST00000133287.1
Stra6
stimulated by retinoic acid gene 6
chr6_-_41772366 0.21 ENSMUST00000050412.4
Olfr459
olfactory receptor 459
chr1_+_86064619 0.21 ENSMUST00000027432.8
Psmd1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr10_+_104142987 0.21 ENSMUST00000181634.1
Gm6763
predicted gene 6763
chr10_+_104151497 0.21 ENSMUST00000181287.1
Gm6763
predicted gene 6763
chr10_+_104160006 0.21 ENSMUST00000181179.1
Gm8764
predicted gene 8764
chr10_+_104168515 0.21 ENSMUST00000181059.1
Gm21304
predicted gene, 21304
chr10_+_104177024 0.21 ENSMUST00000180889.1
Gm21312
predicted gene, 21312
chr10_+_104185533 0.21 ENSMUST00000181703.1
Gm20765
predicted gene, 20765
chr10_+_104194042 0.21 ENSMUST00000181615.1
Gm4340
predicted gene 4340
chr14_-_48662740 0.20 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr6_-_136173492 0.20 ENSMUST00000111905.1
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr10_+_5639210 0.20 ENSMUST00000019906.4
Vip
vasoactive intestinal polypeptide
chr11_-_75937726 0.20 ENSMUST00000121287.1
Rph3al
rabphilin 3A-like (without C2 domains)
chr5_+_87925579 0.20 ENSMUST00000001667.6
ENSMUST00000113267.1
Csn3
casein kappa
chr5_-_76905463 0.20 ENSMUST00000146570.1
ENSMUST00000142450.1
ENSMUST00000120963.1
Aasdh
aminoadipate-semialdehyde dehydrogenase
chrX_-_157415286 0.19 ENSMUST00000079945.4
ENSMUST00000138396.1
Phex
phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)
chr1_+_6487231 0.18 ENSMUST00000140079.1
ENSMUST00000131494.1
St18
suppression of tumorigenicity 18
chr11_+_102285161 0.18 ENSMUST00000156326.1
Tmub2
transmembrane and ubiquitin-like domain containing 2
chr17_+_24632671 0.16 ENSMUST00000047611.2
Nthl1
nth (endonuclease III)-like 1 (E.coli)
chr10_+_104194457 0.15 ENSMUST00000181036.1
Gm4340
predicted gene 4340
chr10_+_104143402 0.15 ENSMUST00000180664.1
Gm6763
predicted gene 6763
chr10_+_104151912 0.15 ENSMUST00000180692.1
Gm6763
predicted gene 6763
chr10_+_104160421 0.15 ENSMUST00000181166.1
Gm8764
predicted gene 8764
chr10_+_104168930 0.15 ENSMUST00000180568.1
Gm21304
predicted gene, 21304
chr10_+_104177439 0.15 ENSMUST00000181239.1
Gm21312
predicted gene, 21312
chr10_+_104185948 0.15 ENSMUST00000181707.1
Gm20765
predicted gene, 20765
chr1_-_134549663 0.15 ENSMUST00000172898.1
4931440L10Rik
RIKEN cDNA 4931440L10 gene
chr3_+_89773562 0.13 ENSMUST00000038356.8
Ube2q1
ubiquitin-conjugating enzyme E2Q (putative) 1
chr7_-_42933789 0.12 ENSMUST00000163803.1
Vmn2r63
vomeronasal 2, receptor 63
chr5_+_34336289 0.11 ENSMUST00000182709.1
ENSMUST00000030992.6
Rnf4
ring finger protein 4
chr13_-_22828114 0.11 ENSMUST00000072044.1
Vmn1r210
vomeronasal 1 receptor 210
chr11_+_110968056 0.11 ENSMUST00000125692.1
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr1_+_131153175 0.11 ENSMUST00000112446.2
ENSMUST00000068805.7
ENSMUST00000068791.4
Eif2d
eukaryotic translation initiation factor 2D
chr2_-_119662756 0.10 ENSMUST00000028768.1
ENSMUST00000110801.1
ENSMUST00000110802.1
Ndufaf1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1
chr1_+_134385938 0.10 ENSMUST00000162187.1
4933406M09Rik
RIKEN cDNA 4933406M09 gene
chrM_+_7759 0.08 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr19_+_44759916 0.07 ENSMUST00000173346.2
Pax2
paired box gene 2
chr15_-_103429547 0.07 ENSMUST00000146736.1
Gtsf1
gametocyte specific factor 1
chrX_+_14211148 0.06 ENSMUST00000079952.2
Gm5382
predicted gene 5382
chr19_-_11336107 0.06 ENSMUST00000056035.2
ENSMUST00000067532.4
Ms4a7
membrane-spanning 4-domains, subfamily A, member 7
chr10_+_34037597 0.06 ENSMUST00000095758.1
Trappc3l
trafficking protein particle complex 3 like
chr15_-_98220897 0.02 ENSMUST00000155603.1
Olfr287
olfactory receptor 287
chr1_+_72307413 0.02 ENSMUST00000027379.8
Xrcc5
X-ray repair complementing defective repair in Chinese hamster cells 5
chr1_-_30999905 0.02 ENSMUST00000152491.1
Gm5699
predicted gene 5699
chr8_+_34054622 0.02 ENSMUST00000149618.1
Gm9951
predicted gene 9951
chr14_-_46831984 0.02 ENSMUST00000181311.1
ENSMUST00000074862.2
Gm10101
predicted gene 10101
chr7_-_103768395 0.01 ENSMUST00000106878.1
Olfr69
olfactory receptor 69
chr5_-_76363787 0.00 ENSMUST00000031146.2
Nmu
neuromedin U
chr14_+_54625305 0.00 ENSMUST00000097177.4
Psmb11
proteasome (prosome, macropain) subunit, beta type, 11

Network of associatons between targets according to the STRING database.

First level regulatory network of Lhx8

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0043387 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377)
0.7 2.2 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.6 2.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.4 1.9 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.3 1.2 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.2 0.9 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.2 2.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 2.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.2 0.7 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.1 2.1 GO:0030497 fatty acid elongation(GO:0030497)
0.1 0.4 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.1 0.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 3.8 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.3 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 4.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.4 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.9 GO:0050955 thermoception(GO:0050955)
0.1 0.7 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.2 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.7 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 1.0 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.4 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.2 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.2 GO:0006296 base-excision repair, AP site formation(GO:0006285) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.1 0.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 3.0 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 3.6 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 1.4 GO:0046688 response to copper ion(GO:0046688)
0.0 1.3 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.3 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.2 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 0.7 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.9 GO:0010107 potassium ion import(GO:0010107)
0.0 1.2 GO:0051180 vitamin transport(GO:0051180)
0.0 0.1 GO:2000595 optic nerve formation(GO:0021634) regulation of metanephros size(GO:0035566) optic chiasma development(GO:0061360) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.6 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.4 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.0 1.1 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.7 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.4 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.3 GO:0030238 male sex determination(GO:0030238)
0.0 0.3 GO:0050901 leukocyte tethering or rolling(GO:0050901)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.4 1.3 GO:0034657 GID complex(GO:0034657)
0.2 1.0 GO:0031673 H zone(GO:0031673)
0.1 0.4 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 1.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.8 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 2.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 2.8 GO:0044438 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 1.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.8 GO:0005844 polysome(GO:0005844)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 8.9 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.7 2.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.4 1.2 GO:0008431 vitamin E binding(GO:0008431)
0.3 0.8 GO:1902121 NADP+ binding(GO:0070401) lithocholic acid binding(GO:1902121)
0.2 0.7 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 2.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 8.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 6.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.5 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 3.8 GO:0070330 aromatase activity(GO:0070330)
0.1 2.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.3 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.1 2.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.9 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 0.7 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.9 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.7 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 2.4 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.9 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.4 GO:0050692 DBD domain binding(GO:0050692)
0.0 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 1.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 2.3 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 5.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 2.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.6 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification