Project

GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Maff

Z-value: 0.89

Motif logo

Transcription factors associated with Maff

Gene Symbol Gene ID Gene Info
ENSMUSG00000042622.7 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Maffmm10_v2_chr15_+_79347534_793475560.617.0e-05Click!

Activity profile of Maff motif

Sorted Z-values of Maff motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_88205674 7.45 ENSMUST00000119972.2
DnaJ (Hsp40) homolog, subfamily B, member 3
chr19_+_58728887 7.13 ENSMUST00000048644.5
pancreatic lipase related protein 1
chr6_-_40999479 6.07 ENSMUST00000166306.1
predicted gene 2663
chr6_+_40964760 5.67 ENSMUST00000076638.5
RIKEN cDNA 1810009J06 gene
chr5_-_67815852 5.20 ENSMUST00000141443.1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr5_+_106964319 4.99 ENSMUST00000031221.5
ENSMUST00000117196.2
ENSMUST00000076467.6
cell division cycle 7 (S. cerevisiae)
chr7_+_35449035 4.94 ENSMUST00000118969.1
ENSMUST00000118383.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr14_+_118787894 4.38 ENSMUST00000047761.6
ENSMUST00000071546.7
claudin 10
chr7_+_35449154 3.46 ENSMUST00000032703.9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chrX_+_93675088 3.29 ENSMUST00000045898.3
phosphate cytidylyltransferase 1, choline, beta isoform
chr6_-_136401830 3.21 ENSMUST00000058713.7
RIKEN cDNA E330021D16 gene
chr6_-_78378851 3.12 ENSMUST00000089667.1
ENSMUST00000167492.1
regenerating islet-derived 3 delta
chr2_-_127831817 3.04 ENSMUST00000028858.7
budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)
chr5_+_140505550 2.68 ENSMUST00000043050.8
ENSMUST00000124142.1
carbohydrate sulfotransferase 12
chr15_-_78572754 2.44 ENSMUST00000043214.6
RAS-related C3 botulinum substrate 2
chr7_-_110862944 2.35 ENSMUST00000033050.3
lymphatic vessel endothelial hyaluronan receptor 1
chr10_-_88605017 2.17 ENSMUST00000119185.1
ENSMUST00000121629.1
myosin binding protein C, slow-type
chr7_+_46861203 2.15 ENSMUST00000014545.4
lactate dehydrogenase C
chr18_+_60963517 1.95 ENSMUST00000115295.2
ENSMUST00000039904.6
calcium/calmodulin-dependent protein kinase II alpha
chr2_-_69206146 1.86 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr2_-_69206133 1.85 ENSMUST00000112320.1
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr7_+_30493622 1.68 ENSMUST00000058280.6
ENSMUST00000133318.1
ENSMUST00000142575.1
ENSMUST00000131040.1
proline dehydrogenase (oxidase) 2
chr3_+_109573907 1.66 ENSMUST00000106576.2
vav 3 oncogene
chr11_-_109473598 1.52 ENSMUST00000070152.5
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr11_+_82101836 1.50 ENSMUST00000000194.3
chemokine (C-C motif) ligand 12
chr7_+_84528964 1.47 ENSMUST00000180387.1
predicted gene 2115
chr17_-_67950908 1.40 ENSMUST00000164647.1
Rho GTPase activating protein 28
chr11_+_119229092 1.38 ENSMUST00000053440.7
coiled-coil domain containing 40
chr2_-_20943413 1.33 ENSMUST00000140230.1
Rho GTPase activating protein 21
chr15_-_25413752 1.31 ENSMUST00000058845.7
brain abundant, membrane attached signal protein 1
chr1_+_75382114 1.25 ENSMUST00000113590.1
ENSMUST00000148515.1
SPEG complex locus
chr18_+_46850034 1.16 ENSMUST00000025358.2
RIKEN cDNA 4833403I15 gene
chr7_-_64925560 1.16 ENSMUST00000149851.1
family with sequence similarity 189, member A1
chr9_-_111690313 1.16 ENSMUST00000035083.7
src homology three (SH3) and cysteine rich domain
chr12_+_16894894 1.06 ENSMUST00000020904.6
Rho-associated coiled-coil containing protein kinase 2
chr7_-_100964371 0.93 ENSMUST00000060174.4
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr8_-_12672135 0.93 ENSMUST00000000776.8
tubulin, gamma complex associated protein 3
chr5_-_135251209 0.92 ENSMUST00000062572.2
frizzled homolog 9 (Drosophila)
chr5_+_110839973 0.90 ENSMUST00000066160.1
checkpoint kinase 2
chr5_+_103754560 0.84 ENSMUST00000153165.1
ENSMUST00000031256.5
AF4/FMR2 family, member 1
chr17_+_86963279 0.82 ENSMUST00000139344.1
ras homolog gene family, member Q
chr1_-_161979636 0.75 ENSMUST00000162676.1
RIKEN cDNA 4930558K02 gene
chr14_+_66784523 0.74 ENSMUST00000071522.2
predicted gene 10032
chr18_+_65582390 0.74 ENSMUST00000169679.1
ENSMUST00000183326.1
zinc finger protein 532
chr3_-_59262825 0.69 ENSMUST00000050360.7
purinergic receptor P2Y, G-protein coupled 12
chr18_-_63387124 0.67 ENSMUST00000047480.6
ENSMUST00000046860.5
piezo-type mechanosensitive ion channel component 2
chr19_+_56722372 0.63 ENSMUST00000038949.4
adrenergic receptor, beta 1
chr15_+_99972780 0.61 ENSMUST00000100206.2
La ribonucleoprotein domain family, member 4
chr6_+_120773633 0.56 ENSMUST00000112682.2
solute carrier family 25 (mitochondrial carrier), member 18
chr7_+_16944645 0.56 ENSMUST00000094807.5
PNMA-like 2
chr17_-_25570678 0.52 ENSMUST00000025003.3
ENSMUST00000173447.1
SRY-box containing gene 8
chr4_+_94556546 0.50 ENSMUST00000094969.1
predicted gene 10306
chr14_+_20929416 0.50 ENSMUST00000022369.7
vinculin
chr5_-_35525691 0.49 ENSMUST00000038676.5
carboxypeptidase Z
chr18_+_33464163 0.43 ENSMUST00000097634.3
predicted gene 10549
chr5_+_7179299 0.40 ENSMUST00000179460.1
tubulin, beta 4B class IVB, pseudogene 1
chr7_+_44052290 0.38 ENSMUST00000079859.5
kallikrein 1-related peptidase b27
chr4_-_143299463 0.37 ENSMUST00000119654.1
podoplanin
chr11_+_75651504 0.35 ENSMUST00000069057.6
myosin IC
chr13_-_54749849 0.30 ENSMUST00000135343.1
G protein-regulated inducer of neurite outgrowth 1
chr1_-_75232093 0.26 ENSMUST00000180101.1
RIKEN cDNA A630095N17 gene
chr6_+_71293765 0.25 ENSMUST00000114185.2
predicted gene 1070
chr17_+_27839974 0.25 ENSMUST00000071006.7
U1 small nuclear ribonucleoprotein C
chr1_+_136017967 0.24 ENSMUST00000063719.8
ENSMUST00000118832.1
transmembrane protein 9
chr4_-_94556737 0.23 ENSMUST00000030313.8
caspase activity and apoptosis inhibitor 1
chr3_+_127791374 0.23 ENSMUST00000171621.1
TRAF-interacting protein with forkhead-associated domain
chr2_+_121866918 0.21 ENSMUST00000078752.3
ENSMUST00000110586.3
cancer susceptibility candidate 4
chr3_+_28805436 0.19 ENSMUST00000043867.5
ribosomal protein L22 like 1
chr11_-_118342500 0.19 ENSMUST00000103024.3
cDNA sequence BC100451
chr5_+_8056527 0.18 ENSMUST00000148633.1
sorcin
chr18_-_33463747 0.17 ENSMUST00000171533.1
neuronal regeneration related protein
chr7_+_46861407 0.17 ENSMUST00000126004.1
lactate dehydrogenase C
chr7_+_30314810 0.16 ENSMUST00000054594.8
ENSMUST00000177078.1
ENSMUST00000176504.1
ENSMUST00000176304.1
spectrin repeat containing, nuclear envelope family member 4
chr4_-_136886187 0.12 ENSMUST00000046384.8
complement component 1, q subcomponent, beta polypeptide
chr2_+_121867083 0.12 ENSMUST00000089912.5
ENSMUST00000089915.3
cancer susceptibility candidate 4
chr3_-_108154871 0.12 ENSMUST00000062028.1
G protein-coupled receptor 61
chr8_+_25532125 0.09 ENSMUST00000167764.1
fibroblast growth factor receptor 1
chr13_+_3924686 0.09 ENSMUST00000021639.6
tubulin, alpha-like 3
chr11_+_83709015 0.08 ENSMUST00000001009.7
WAP four-disulfide core domain 18
chr18_-_33464007 0.08 ENSMUST00000168890.1
neuronal regeneration related protein
chr12_+_104263117 0.08 ENSMUST00000109958.2
serine (or cysteine) peptidase inhibitor, clade A, member 3I
chr10_-_121626316 0.07 ENSMUST00000039810.7
exportin, tRNA (nuclear export receptor for tRNAs)
chr7_+_46861253 0.07 ENSMUST00000148565.1
lactate dehydrogenase C
chr5_-_35525567 0.06 ENSMUST00000132959.1
carboxypeptidase Z
chr6_+_83795022 0.06 ENSMUST00000113851.1
N-acetylglucosamine kinase
chr16_-_22439719 0.06 ENSMUST00000079601.6
ets variant gene 5
chr9_+_65460926 0.06 ENSMUST00000034955.6
spastic paraplegia 21 homolog (human)
chr11_+_76945719 0.05 ENSMUST00000125145.1
bleomycin hydrolase
chr9_-_57765845 0.04 ENSMUST00000065330.6
CDC-like kinase 3
chr13_-_54749627 0.02 ENSMUST00000099506.1
G protein-regulated inducer of neurite outgrowth 1
chr6_+_83794974 0.02 ENSMUST00000037376.7
N-acetylglucosamine kinase
chr18_+_32377176 0.01 ENSMUST00000091967.5
ENSMUST00000025239.7
bridging integrator 1
chr17_+_26138661 0.01 ENSMUST00000074370.3
ENSMUST00000118904.2
ENSMUST00000163421.1
axin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Maff

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.4 GO:0015811 L-cystine transport(GO:0015811)
1.0 3.0 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.9 2.7 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.8 5.0 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.7 5.2 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.6 1.7 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.5 2.4 GO:0019516 lactate oxidation(GO:0019516)
0.4 1.5 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.3 1.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 0.9 GO:1990523 bone regeneration(GO:1990523)
0.3 2.4 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.3 0.9 GO:0098763 mitotic cell cycle phase(GO:0098763)
0.3 1.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.2 1.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.2 1.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.2 0.6 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.2 0.5 GO:0072034 renal vesicle induction(GO:0072034)
0.2 0.7 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 2.0 GO:0098970 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 2.4 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 2.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.9 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.4 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.9 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 1.3 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 1.7 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 3.3 GO:0001541 ovarian follicle development(GO:0001541)
0.0 3.7 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.5 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
0.0 0.2 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.0 0.1 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.7 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 1.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 1.3 GO:0055013 cardiac muscle cell development(GO:0055013)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.7 3.7 GO:0031262 Ndc80 complex(GO:0031262)
0.5 2.0 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.1 0.9 GO:0005827 equatorial microtubule organizing center(GO:0000923) polar microtubule(GO:0005827)
0.1 0.3 GO:0045160 myosin I complex(GO:0045160)
0.1 5.0 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.2 GO:0005859 muscle myosin complex(GO:0005859)
0.1 8.4 GO:0031526 brush border membrane(GO:0031526)
0.1 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 1.3 GO:0031527 filopodium membrane(GO:0031527)
0.1 7.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 1.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 5.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.4 GO:0031514 motile cilium(GO:0031514)
0.0 3.3 GO:0005884 actin filament(GO:0005884)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 2.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640) nuclear membrane part(GO:0044453)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.4 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.9 2.7 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.7 3.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.4 7.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.4 1.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.3 2.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 0.9 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.2 2.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 5.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 0.6 GO:0031694 beta-adrenergic receptor activity(GO:0004939) alpha-2A adrenergic receptor binding(GO:0031694)
0.1 2.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 2.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.8 GO:0005522 profilin binding(GO:0005522)
0.1 12.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.7 GO:0071949 FAD binding(GO:0071949)
0.0 1.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162) alpha-catenin binding(GO:0045294)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.4 GO:0015250 water channel activity(GO:0015250)
0.0 1.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 10.6 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 4.1 PID PLK1 PATHWAY PLK1 signaling events
0.1 2.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID ATM PATHWAY ATM pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 2.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 5.0 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 2.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 0.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 5.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 3.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 3.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 0.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 2.0 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 6.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.7 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators