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GSE58827: Dynamics of the Mouse Liver

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Results for Myf6

Z-value: 2.25

Motif logo

Transcription factors associated with Myf6

Gene Symbol Gene ID Gene Info
ENSMUSG00000035923.3 myogenic factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Myf6mm10_v2_chr10_-_107494719_107494742-0.391.8e-02Click!

Activity profile of Myf6 motif

Sorted Z-values of Myf6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_62087261 23.15 ENSMUST00000107488.3
ENSMUST00000107472.1
ENSMUST00000084531.4
major urinary protein 3
chr4_-_60070411 21.57 ENSMUST00000079697.3
ENSMUST00000125282.1
ENSMUST00000166098.1
major urinary protein 7
chr4_-_60501903 21.25 ENSMUST00000084548.4
ENSMUST00000103012.3
ENSMUST00000107499.3
major urinary protein 1
chr4_-_60662358 21.17 ENSMUST00000084544.4
ENSMUST00000098046.3
major urinary protein 11
chr4_-_61674094 21.13 ENSMUST00000098040.3
major urinary protein 18
chr4_-_60421933 20.71 ENSMUST00000107506.2
ENSMUST00000122381.1
ENSMUST00000118759.1
ENSMUST00000122177.1
major urinary protein 9
chr4_-_61303998 20.43 ENSMUST00000071005.8
ENSMUST00000075206.5
major urinary protein 14
chr4_-_60741275 19.90 ENSMUST00000117932.1
major urinary protein 12
chr4_-_60222580 19.64 ENSMUST00000095058.4
ENSMUST00000163931.1
major urinary protein 8
chr4_-_61303802 19.56 ENSMUST00000125461.1
major urinary protein 14
chr10_+_128971191 19.54 ENSMUST00000181142.1
RIKEN cDNA 9030616G12 gene
chr10_+_87860030 19.51 ENSMUST00000062862.6
insulin-like growth factor 1
chr4_-_60139857 18.00 ENSMUST00000107490.4
ENSMUST00000074700.2
major urinary protein 2
chr10_-_128960965 14.03 ENSMUST00000026398.3
methyltransferase like 7B
chr4_-_60582152 12.14 ENSMUST00000098047.2
major urinary protein 10
chr6_-_85707858 11.29 ENSMUST00000179613.1
predicted gene 4477
chr16_+_91269759 11.02 ENSMUST00000056882.5
oligodendrocyte transcription factor 1
chr15_-_86033777 9.71 ENSMUST00000016172.7
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr7_-_114562945 9.31 ENSMUST00000119712.1
ENSMUST00000032908.8
cytochrome P450, family 2, subfamily r, polypeptide 1
chr4_+_60003438 9.12 ENSMUST00000107517.1
ENSMUST00000107520.1
major urinary protein 6
chr1_+_167598450 9.09 ENSMUST00000111386.1
ENSMUST00000111384.1
retinoid X receptor gamma
chr12_+_108334341 8.61 ENSMUST00000021684.4
cytochrome P450, family 46, subfamily a, polypeptide 1
chr1_+_167598384 8.43 ENSMUST00000015987.3
retinoid X receptor gamma
chr16_-_46496772 8.35 ENSMUST00000149901.1
ENSMUST00000096052.2
poliovirus receptor-related 3
chr11_+_99879187 8.28 ENSMUST00000078442.3
predicted gene 11567
chr15_-_3582596 8.19 ENSMUST00000161770.1
growth hormone receptor
chr10_+_127866457 8.06 ENSMUST00000092058.3
cDNA sequence BC089597
chr7_+_51879041 7.98 ENSMUST00000107591.2
growth arrest specific 2
chr1_+_72824482 7.79 ENSMUST00000047328.4
insulin-like growth factor binding protein 2
chr11_+_99864476 7.73 ENSMUST00000092694.3
predicted gene 11559
chr16_-_18089022 7.38 ENSMUST00000132241.1
ENSMUST00000139861.1
ENSMUST00000003620.5
proline dehydrogenase
chr18_+_60803838 7.00 ENSMUST00000050487.8
ENSMUST00000097563.2
ENSMUST00000167610.1
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
chr7_+_51878967 6.96 ENSMUST00000051912.6
growth arrest specific 2
chr15_-_89373810 6.83 ENSMUST00000167643.2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr1_-_121327672 6.77 ENSMUST00000159085.1
ENSMUST00000159125.1
ENSMUST00000161818.1
insulin induced gene 2
chr14_+_65968483 6.71 ENSMUST00000022616.6
clusterin
chr2_+_34772089 6.59 ENSMUST00000028222.6
ENSMUST00000100171.2
heat shock protein 5
chr17_-_34000257 6.44 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
histocompatibility 2, K1, K region
chr1_-_121327734 6.36 ENSMUST00000160968.1
ENSMUST00000162582.1
insulin induced gene 2
chr2_-_24048857 6.35 ENSMUST00000114497.1
histamine N-methyltransferase
chr10_+_116301374 6.32 ENSMUST00000092167.5
protein tyrosine phosphatase, receptor type, B
chr1_-_121328024 6.26 ENSMUST00000003818.7
insulin induced gene 2
chr9_-_43239816 6.18 ENSMUST00000034512.5
OAF homolog (Drosophila)
chr14_-_79662084 6.09 ENSMUST00000165835.1
leukocyte cell derived chemotaxin 1
chr5_+_30588078 6.04 ENSMUST00000066295.2
potassium channel, subfamily K, member 3
chr7_-_142229971 6.02 ENSMUST00000097942.2
keratin associated protein 5-5
chr16_-_46496955 6.02 ENSMUST00000023335.6
ENSMUST00000023334.8
poliovirus receptor-related 3
chr1_+_57377593 5.94 ENSMUST00000042734.2
RIKEN cDNA 1700066M21 gene
chr3_+_94372794 5.83 ENSMUST00000029795.3
RAR-related orphan receptor gamma
chr1_-_121327776 5.79 ENSMUST00000160688.1
insulin induced gene 2
chr15_-_39857459 5.70 ENSMUST00000022915.3
ENSMUST00000110306.1
dihydropyrimidinase
chr3_-_89322883 5.61 ENSMUST00000029673.5
ephrin A3
chr2_-_181043540 5.50 ENSMUST00000124400.1
cholinergic receptor, nicotinic, alpha polypeptide 4
chr19_+_26605106 5.44 ENSMUST00000025862.7
ENSMUST00000176030.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr8_-_84011442 5.37 ENSMUST00000056686.5
RIKEN cDNA 2210011C24 gene
chr14_-_79662148 5.35 ENSMUST00000022603.7
leukocyte cell derived chemotaxin 1
chr7_-_99626936 5.30 ENSMUST00000178124.1
predicted gene 4980
chr5_-_53213447 5.27 ENSMUST00000031090.6
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr17_+_35320529 5.24 ENSMUST00000105041.3
ENSMUST00000073208.5
histocompatibility 2, Q region locus 1
chr17_+_4994904 5.20 ENSMUST00000092723.4
ENSMUST00000115797.2
AT rich interactive domain 1B (SWI-like)
chr7_+_44590886 5.20 ENSMUST00000107906.3
potassium voltage gated channel, Shaw-related subfamily, member 3
chr1_-_180195981 5.20 ENSMUST00000027766.6
ENSMUST00000161814.1
aarF domain containing kinase 3
chr1_-_136260873 5.15 ENSMUST00000086395.5
G protein-coupled receptor 25
chr11_+_104231390 5.15 ENSMUST00000106992.3
microtubule-associated protein tau
chr10_-_20548361 5.07 ENSMUST00000164195.1
phosphodiesterase 7B
chr6_-_120294559 5.07 ENSMUST00000057283.7
beta-1,4-N-acetyl-galactosaminyl transferase 3
chr5_+_43233928 5.06 ENSMUST00000114066.1
ENSMUST00000114065.1
cytoplasmic polyadenylation element binding protein 2
chrX_-_72656135 5.05 ENSMUST00000055966.6
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr17_-_46752170 5.05 ENSMUST00000121671.1
ENSMUST00000059844.6
canopy 3 homolog (zebrafish)
chr14_+_65971164 4.96 ENSMUST00000144619.1
clusterin
chr18_-_61536522 4.90 ENSMUST00000171629.1
Rho guanine nucleotide exchange factor (GEF) 37
chr8_-_94696223 4.83 ENSMUST00000034227.4
plasma membrane proteolipid
chr9_+_55326913 4.80 ENSMUST00000085754.3
ENSMUST00000034862.4
expressed sequence AI118078
chr5_+_43233463 4.80 ENSMUST00000169035.1
ENSMUST00000166713.1
cytoplasmic polyadenylation element binding protein 2
chr11_+_115163333 4.76 ENSMUST00000021077.3
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr4_+_133553370 4.75 ENSMUST00000042706.2
nuclear receptor subfamily 0, group B, member 2
chr19_-_42202150 4.67 ENSMUST00000018966.7
secreted frizzled-related sequence protein 5
chr15_+_88819584 4.49 ENSMUST00000024042.3
cysteine-rich with EGF-like domains 2
chr17_-_57228003 4.48 ENSMUST00000177046.1
ENSMUST00000024988.8
complement component 3
chr19_+_7056731 4.48 ENSMUST00000040261.5
MACRO domain containing 1
chr10_-_20548320 4.47 ENSMUST00000169404.1
phosphodiesterase 7B
chr1_-_133921393 4.44 ENSMUST00000048432.5
proline arginine-rich end leucine-rich repeat
chr5_-_87591582 4.41 ENSMUST00000031201.7
sulfotransferase family 1E, member 1
chr7_+_24481991 4.40 ENSMUST00000068023.7
cell adhesion molecule 4
chr11_+_99785191 4.36 ENSMUST00000105059.2
keratin associated protein 4-9
chr10_+_127776374 4.33 ENSMUST00000136223.1
ENSMUST00000052652.6
retinol dehydrogenase 9
chr4_-_66404512 4.32 ENSMUST00000068214.4
astrotactin 2
chr11_+_99873389 4.26 ENSMUST00000093936.3
keratin associated protein 9-1
chr17_-_34804546 4.12 ENSMUST00000025223.8
cytochrome P450, family 21, subfamily a, polypeptide 1
chr17_-_87282793 4.06 ENSMUST00000146560.2
RIKEN cDNA 4833418N02 gene
chr7_-_12998140 3.96 ENSMUST00000032539.7
solute carrier family 27 (fatty acid transporter), member 5
chr10_-_114801364 3.87 ENSMUST00000061632.7
TRH-degrading enzyme
chr15_+_76268076 3.85 ENSMUST00000074173.3
spermatogenesis and centriole associated 1
chr10_+_7589885 3.85 ENSMUST00000130590.1
ENSMUST00000135907.1
low density lipoprotein receptor-related protein 11
chr2_-_26604267 3.80 ENSMUST00000028286.5
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr11_-_99620432 3.71 ENSMUST00000073853.2
predicted gene 11562
chr10_-_81545175 3.69 ENSMUST00000043604.5
guanine nucleotide binding protein, alpha 11
chr13_+_93771656 3.64 ENSMUST00000091403.4
arylsulfatase B
chr9_-_114844090 3.64 ENSMUST00000047013.3
CKLF-like MARVEL transmembrane domain containing 8
chr4_+_135920731 3.62 ENSMUST00000030434.4
fucosidase, alpha-L- 1, tissue
chr17_+_43801823 3.61 ENSMUST00000044895.5
regulator of calcineurin 2
chr11_+_102435285 3.60 ENSMUST00000125819.2
ENSMUST00000177428.1
granulin
chr11_+_99041237 3.59 ENSMUST00000017637.6
insulin-like growth factor binding protein 4
chr11_+_104231573 3.59 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
microtubule-associated protein tau
chr19_+_5038826 3.58 ENSMUST00000053705.6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr4_-_124850670 3.57 ENSMUST00000163946.1
ENSMUST00000106190.3
RIKEN cDNA 1110065P20 gene
chr10_+_7589788 3.57 ENSMUST00000134346.1
ENSMUST00000019931.5
low density lipoprotein receptor-related protein 11
chr13_+_64161862 3.49 ENSMUST00000021929.8
hyaluronic acid binding protein 4
chr7_-_19149189 3.43 ENSMUST00000032566.1
glutaminyl-peptide cyclotransferase-like
chr17_+_35262730 3.41 ENSMUST00000172785.1
histocompatibility 2, D region locus 1
chr19_+_36554661 3.37 ENSMUST00000169036.2
ENSMUST00000047247.5
HECT domain containing 2
chr17_+_32506446 3.36 ENSMUST00000165999.1
cytochrome P450, family 4, subfamily f, polypeptide 17
chr4_-_138367966 3.35 ENSMUST00000030535.3
cytidine deaminase
chr2_-_71750083 3.33 ENSMUST00000180494.1
predicted gene, 17250
chr2_+_173153048 3.31 ENSMUST00000029017.5
phosphoenolpyruvate carboxykinase 1, cytosolic
chr5_-_34187670 3.27 ENSMUST00000042701.6
ENSMUST00000119171.1
Max dimerization protein 4
chr4_-_124850473 3.26 ENSMUST00000137769.2
RIKEN cDNA 1110065P20 gene
chr4_+_152008803 3.25 ENSMUST00000097773.3
kelch-like 21
chr18_+_12333953 3.22 ENSMUST00000092070.6
laminin, alpha 3
chr1_+_88200601 3.21 ENSMUST00000049289.8
UDP glucuronosyltransferase 1 family, polypeptide A2
chr2_-_181039286 3.20 ENSMUST00000067120.7
cholinergic receptor, nicotinic, alpha polypeptide 4
chr9_-_97018823 3.19 ENSMUST00000055433.4
splA/ryanodine receptor domain and SOCS box containing 4
chr1_-_106759727 3.17 ENSMUST00000010049.4
3-ketodihydrosphingosine reductase
chr6_-_147087023 3.12 ENSMUST00000100780.2
MANSC domain containing 4
chr7_+_35119285 3.11 ENSMUST00000042985.9
CCAAT/enhancer binding protein (C/EBP), alpha
chr2_+_18672384 3.09 ENSMUST00000171845.1
ENSMUST00000061158.4
COMM domain containing 3
chr5_-_140830430 3.08 ENSMUST00000000153.4
guanine nucleotide binding protein, alpha 12
chr7_+_16309577 3.08 ENSMUST00000002152.6
BCL2 binding component 3
chr11_-_106487833 3.04 ENSMUST00000106801.1
endoplasmic reticulum (ER) to nucleus signalling 1
chr2_-_181039160 3.02 ENSMUST00000108851.1
cholinergic receptor, nicotinic, alpha polypeptide 4
chr4_+_105157339 3.02 ENSMUST00000064139.7
phosphatidic acid phosphatase type 2B
chr5_+_87000838 3.01 ENSMUST00000031186.7
UDP glucuronosyltransferase 2 family, polypeptide B35
chr2_+_25428699 3.01 ENSMUST00000102919.3
ATP-binding cassette, sub-family A (ABC1), member 2
chr16_+_37868383 3.00 ENSMUST00000078717.6
leucine rich repeat containing 58
chr17_+_35470083 2.99 ENSMUST00000174525.1
ENSMUST00000068291.6
histocompatibility 2, Q region locus 10
chr11_-_106487796 2.98 ENSMUST00000001059.2
ENSMUST00000106799.1
ENSMUST00000106800.1
endoplasmic reticulum (ER) to nucleus signalling 1
chr10_+_75893398 2.95 ENSMUST00000009236.4
Der1-like domain family, member 3
chr2_+_23069210 2.94 ENSMUST00000155602.1
acyl-Coenzyme A binding domain containing 5
chr4_+_144893077 2.94 ENSMUST00000154208.1
dehydrogenase/reductase (SDR family) member 3
chr17_-_45595842 2.92 ENSMUST00000164618.1
ENSMUST00000097317.3
ENSMUST00000170113.1
solute carrier family 29 (nucleoside transporters), member 1
chr2_-_164443177 2.91 ENSMUST00000017153.3
syndecan 4
chr10_+_61695503 2.87 ENSMUST00000020284.4
trypsin domain containing 1
chr11_-_120784183 2.86 ENSMUST00000026156.7
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr10_-_127888688 2.85 ENSMUST00000047199.4
retinol dehydrogenase 7
chr1_+_88095054 2.85 ENSMUST00000150634.1
ENSMUST00000058237.7
UDP glucuronosyltransferase 1 family, polypeptide A7C
chr9_+_65265173 2.85 ENSMUST00000048762.1
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr3_+_95318782 2.85 ENSMUST00000139866.1
ceramide synthase 2
chr4_-_124850652 2.84 ENSMUST00000125776.1
RIKEN cDNA 1110065P20 gene
chr5_-_92505518 2.83 ENSMUST00000031377.7
scavenger receptor class B, member 2
chr8_-_70857008 2.81 ENSMUST00000110081.3
ENSMUST00000110078.3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
chr13_-_43480973 2.80 ENSMUST00000144326.2
RAN binding protein 9
chr19_-_6067785 2.80 ENSMUST00000162575.1
ENSMUST00000159084.1
ENSMUST00000161718.1
ENSMUST00000162810.1
ENSMUST00000025713.5
ENSMUST00000113543.2
ENSMUST00000161528.1
transmembrane 7 superfamily member 2
chr2_+_23069057 2.80 ENSMUST00000114526.1
ENSMUST00000114529.2
acyl-Coenzyme A binding domain containing 5
chr5_+_35041539 2.79 ENSMUST00000030985.6
hepatocyte growth factor activator
chr6_-_47813512 2.79 ENSMUST00000077290.7
protein disulfide isomerase associated 4
chr17_+_26113286 2.77 ENSMUST00000025010.7
transmembrane protein 8 (five membrane-spanning domains)
chr2_-_91195097 2.77 ENSMUST00000002177.2
ENSMUST00000111354.1
nuclear receptor subfamily 1, group H, member 3
chr17_-_32947372 2.75 ENSMUST00000139353.1
cytochrome P450, family 4, subfamily f, polypeptide 13
chrX_+_100767719 2.74 ENSMUST00000000901.6
ENSMUST00000113736.2
ENSMUST00000087984.4
discs, large homolog 3 (Drosophila)
chr4_+_144892813 2.73 ENSMUST00000105744.1
ENSMUST00000171001.1
dehydrogenase/reductase (SDR family) member 3
chr7_+_130936172 2.73 ENSMUST00000006367.7
HtrA serine peptidase 1
chr6_-_72617000 2.71 ENSMUST00000070524.4
trans-golgi network protein
chr11_+_50602072 2.70 ENSMUST00000040523.8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr10_-_127351753 2.68 ENSMUST00000059718.4
inhibin beta E
chr7_+_101394361 2.67 ENSMUST00000154239.1
ENSMUST00000098243.2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr17_-_32947389 2.67 ENSMUST00000075253.6
cytochrome P450, family 4, subfamily f, polypeptide 13
chr3_+_135826075 2.66 ENSMUST00000029810.5
solute carrier family 39 (metal ion transporter), member 8
chr6_-_11907419 2.65 ENSMUST00000031637.5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4
chr4_+_144893127 2.65 ENSMUST00000142808.1
dehydrogenase/reductase (SDR family) member 3
chr11_-_95587691 2.63 ENSMUST00000000122.6
nerve growth factor receptor (TNFR superfamily, member 16)
chr11_+_104231465 2.63 ENSMUST00000145227.1
microtubule-associated protein tau
chr11_+_104231515 2.62 ENSMUST00000106993.3
microtubule-associated protein tau
chr7_+_3694512 2.61 ENSMUST00000108627.3
tRNA splicing endonuclease 34 homolog (S. cerevisiae)
chr1_-_72212249 2.61 ENSMUST00000048860.7
melanoregulin
chr17_-_36129425 2.61 ENSMUST00000046131.9
ENSMUST00000173322.1
ENSMUST00000172968.1
predicted gene 7030
chr2_+_55437100 2.57 ENSMUST00000112633.2
ENSMUST00000112632.1
potassium inwardly-rectifying channel, subfamily J, member 3
chr10_-_24101951 2.56 ENSMUST00000170267.1
trace amine-associated receptor 8C
chr8_-_69890967 2.56 ENSMUST00000152938.1
YjeF N-terminal domain containing 3
chr9_+_6168638 2.55 ENSMUST00000058692.7
platelet-derived growth factor, D polypeptide
chr11_-_115187827 2.55 ENSMUST00000103041.1
N-acetyltransferase 9 (GCN5-related, putative)
chr3_+_54735536 2.53 ENSMUST00000044567.3
asparagine-linked glycosylation 5 (dolichyl-phosphate beta-glucosyltransferase)
chrX_-_112698642 2.53 ENSMUST00000039887.3
premature ovarian failure 1B
chr10_-_24836165 2.52 ENSMUST00000020169.7
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr19_+_4855129 2.52 ENSMUST00000119694.1
cathepsin F
chr17_+_35342242 2.51 ENSMUST00000074806.5
histocompatibility 2, Q region locus 2
chr16_+_93607831 2.51 ENSMUST00000039659.8
carbonyl reductase 1
chr6_-_124863877 2.51 ENSMUST00000046893.7
G protein-coupled receptor 162
chr1_-_82291370 2.49 ENSMUST00000069799.2
insulin receptor substrate 1
chr7_+_107370728 2.49 ENSMUST00000137663.1
ENSMUST00000073459.5
synaptotagmin IX
chr8_-_84773381 2.49 ENSMUST00000109764.1
nuclear factor I/X
chr16_-_10543028 2.49 ENSMUST00000184863.1
ENSMUST00000038281.5
dexamethasone-induced transcript
chr15_-_74728011 2.49 ENSMUST00000023261.2
secreted Ly6/Plaur domain containing 1
chr4_+_149545102 2.48 ENSMUST00000105692.1
catenin beta interacting protein 1
chr17_+_87282880 2.48 ENSMUST00000041110.5
ENSMUST00000125875.1
tetratricopeptide repeat domain 7
chr9_-_54501496 2.47 ENSMUST00000118600.1
ENSMUST00000118163.1
Dmx-like 2
chr10_-_127621107 2.47 ENSMUST00000049149.8
low density lipoprotein receptor-related protein 1
chr11_-_99851608 2.47 ENSMUST00000107437.1
keratin associated protein 4-16
chr6_-_119330668 2.47 ENSMUST00000112756.1
leucine-rich repeats and transmembrane domains 2
chr7_-_27337667 2.46 ENSMUST00000038618.6
ENSMUST00000108369.2
latent transforming growth factor beta binding protein 4
chr5_+_102845007 2.45 ENSMUST00000070000.4
Rho GTPase activating protein 24

Network of associatons between targets according to the STRING database.

First level regulatory network of Myf6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.7 GO:1903048 regulation of acetylcholine-gated cation channel activity(GO:1903048)
3.9 42.4 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
3.3 19.5 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
3.2 9.7 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
2.5 12.6 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
2.5 7.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
2.3 11.7 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
2.1 6.4 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
1.9 11.7 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
1.9 5.7 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
1.7 5.2 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
1.7 30.5 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
1.6 4.8 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
1.6 4.7 GO:2000041 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
1.6 14.0 GO:1900034 regulation of cellular response to heat(GO:1900034)
1.5 6.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
1.5 7.4 GO:0009414 response to water deprivation(GO:0009414)
1.4 7.0 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
1.3 5.2 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
1.3 3.9 GO:0018199 peptidyl-glutamine modification(GO:0018199)
1.3 6.3 GO:0001692 histamine metabolic process(GO:0001692)
1.3 10.0 GO:0045900 negative regulation of translational elongation(GO:0045900)
1.2 9.6 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
1.1 3.3 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
1.1 3.3 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
1.0 4.1 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
1.0 4.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
1.0 1.9 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
1.0 2.9 GO:0009804 coumarin metabolic process(GO:0009804) phenylpropanoid catabolic process(GO:0046271)
0.9 2.8 GO:1903334 positive regulation of protein folding(GO:1903334)
0.9 3.7 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.9 4.6 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.9 4.5 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.9 1.8 GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
0.9 2.6 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.8 10.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.8 2.5 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.8 5.7 GO:0030242 pexophagy(GO:0030242)
0.8 8.2 GO:0046449 creatinine metabolic process(GO:0046449)
0.8 22.0 GO:0035634 response to stilbenoid(GO:0035634)
0.8 2.4 GO:0009826 unidimensional cell growth(GO:0009826)
0.8 3.1 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.8 1.5 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.8 2.3 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.8 2.3 GO:1904173 regulation of histone demethylase activity (H3-K4 specific)(GO:1904173)
0.8 5.3 GO:0015862 uridine transport(GO:0015862)
0.8 2.3 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.7 3.7 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.7 4.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.7 4.3 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.7 2.8 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.7 2.7 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.7 2.0 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.7 3.3 GO:0035262 gonad morphogenesis(GO:0035262)
0.7 14.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.6 4.5 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.6 2.5 GO:0042373 vitamin K metabolic process(GO:0042373)
0.6 3.8 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.6 1.2 GO:1900673 olefin metabolic process(GO:1900673)
0.6 5.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.6 3.6 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.6 2.4 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.6 1.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.6 2.9 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.6 0.6 GO:1901662 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.5 6.5 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
0.5 1.1 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.5 8.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.5 2.5 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.5 2.4 GO:0072236 metanephric loop of Henle development(GO:0072236)
0.5 6.6 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.5 2.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.5 3.6 GO:0006004 fucose metabolic process(GO:0006004)
0.4 2.2 GO:0015886 heme transport(GO:0015886)
0.4 0.4 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.4 2.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.4 2.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.4 2.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.4 4.1 GO:0042448 progesterone metabolic process(GO:0042448)
0.4 2.9 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.4 16.9 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.4 1.6 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.4 1.9 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.4 0.8 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.4 3.8 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.4 2.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.4 1.8 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.4 2.8 GO:0015871 choline transport(GO:0015871)
0.3 1.0 GO:0060066 oviduct development(GO:0060066) response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.3 13.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.3 6.8 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.3 1.7 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.3 1.7 GO:0010040 response to iron(II) ion(GO:0010040)
0.3 1.0 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.3 1.0 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.3 1.3 GO:0021660 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.3 3.8 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.3 5.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 3.8 GO:0060134 prepulse inhibition(GO:0060134)
0.3 1.9 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.3 2.7 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.3 3.6 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.3 1.5 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.3 3.2 GO:0052697 flavonoid metabolic process(GO:0009812) flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.3 2.0 GO:0035754 B cell chemotaxis(GO:0035754)
0.3 0.9 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.3 5.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.3 1.4 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.3 4.0 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.3 3.1 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.3 2.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.3 1.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.3 2.8 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.3 5.2 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.3 0.8 GO:1902868 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.3 2.5 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.3 9.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.3 0.8 GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635)
0.3 2.7 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.3 1.8 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.3 0.8 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.3 0.8 GO:0060220 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) negative regulation of immature T cell proliferation in thymus(GO:0033088) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.3 0.8 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.2 1.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.2 3.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 1.7 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.2 2.4 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.2 1.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 1.0 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.2 2.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 0.9 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.2 1.4 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.2 1.2 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.2 3.3 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.2 1.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.2 1.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 2.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 2.5 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 1.5 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2 3.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 1.3 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.2 3.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.2 1.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 1.0 GO:1990034 calcium ion export from cell(GO:1990034)
0.2 0.8 GO:0061056 sclerotome development(GO:0061056)
0.2 1.2 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.2 0.8 GO:0090168 Golgi reassembly(GO:0090168)
0.2 1.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.2 1.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 0.4 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.2 1.9 GO:0099638 endosome to plasma membrane protein transport(GO:0099638)
0.2 0.2 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
0.2 0.8 GO:0072014 proximal tubule development(GO:0072014)
0.2 1.9 GO:0098885 maternal process involved in parturition(GO:0060137) modification of postsynaptic actin cytoskeleton(GO:0098885)
0.2 0.4 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.2 1.7 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.2 2.5 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.2 0.9 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 1.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 1.2 GO:0048102 autophagic cell death(GO:0048102)
0.2 0.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.2 0.5 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2 1.0 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 2.5 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.2 0.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.2 1.8 GO:0007320 insemination(GO:0007320)
0.2 2.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 1.0 GO:0015808 L-alanine transport(GO:0015808)
0.2 1.6 GO:0060268 negative regulation of respiratory burst(GO:0060268)
0.2 2.7 GO:0000338 protein deneddylation(GO:0000338)
0.2 0.5 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2 0.5 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.2 0.9 GO:0015889 cobalamin transport(GO:0015889)
0.2 0.8 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.2 1.2 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.2 0.9 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.4 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.1 3.5 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 0.6 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.6 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) positive regulation of G0 to G1 transition(GO:0070318)
0.1 2.7 GO:0046519 sphingoid metabolic process(GO:0046519)
0.1 1.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.8 GO:1901907 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 1.0 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.6 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.6 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.1 1.9 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.1 2.6 GO:0032402 melanosome transport(GO:0032402)
0.1 0.8 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1 1.2 GO:0006013 mannose metabolic process(GO:0006013)
0.1 4.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 1.9 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.8 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 0.8 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 1.0 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.1 0.5 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.1 1.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 2.1 GO:0070571 negative regulation of neuron projection regeneration(GO:0070571)
0.1 1.0 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.1 4.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.5 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 2.9 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.1 2.7 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 1.0 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 1.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.3 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) activation of meiosis involved in egg activation(GO:0060466)
0.1 0.7 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.1 0.6 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.6 GO:0070459 prolactin secretion(GO:0070459)
0.1 1.1 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.9 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 0.9 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.1 0.3 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.1 2.0 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.1 4.3 GO:0043171 peptide catabolic process(GO:0043171)
0.1 1.7 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.1 0.4 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 5.5 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 1.0 GO:0043144 snoRNA processing(GO:0043144)
0.1 0.8 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.1 1.2 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 2.1 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 0.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 2.3 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 2.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.6 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.2 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 6.8 GO:0048663 neuron fate commitment(GO:0048663)
0.1 0.4 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 3.3 GO:0034629 cellular protein complex localization(GO:0034629)
0.1 0.9 GO:0097421 liver regeneration(GO:0097421)
0.1 1.4 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 1.0 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.2 GO:0010840 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.1 1.2 GO:0030238 male sex determination(GO:0030238)
0.1 0.1 GO:2000646 positive regulation of low-density lipoprotein particle receptor catabolic process(GO:0032805) positive regulation of receptor catabolic process(GO:2000646)
0.1 1.4 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 0.4 GO:0060023 soft palate development(GO:0060023)
0.1 0.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 2.5 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.1 0.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.9 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 2.8 GO:0009268 response to pH(GO:0009268)
0.1 0.2 GO:0003310 pancreatic A cell differentiation(GO:0003310) noradrenergic neuron development(GO:0003358)
0.1 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.7 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 0.9 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 1.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.2 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.1 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 1.5 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.1 1.2 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.1 2.3 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.6 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 2.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 3.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.3 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.1 1.6 GO:0097320 membrane tubulation(GO:0097320)
0.1 1.1 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 2.2 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.1 2.8 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 0.8 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.9 GO:0055078 sodium ion homeostasis(GO:0055078)
0.1 0.4 GO:0033572 transferrin transport(GO:0033572)
0.0 0.5 GO:0030953 positive regulation of centrosome duplication(GO:0010825) astral microtubule organization(GO:0030953)
0.0 1.0 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 1.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 2.4 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.5 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 1.6 GO:0009409 response to cold(GO:0009409)
0.0 6.3 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032434)
0.0 0.7 GO:0006691 leukotriene metabolic process(GO:0006691)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631) positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 5.5 GO:0007050 cell cycle arrest(GO:0007050)
0.0 2.1 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 1.8 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.5 GO:0008272 sulfate transport(GO:0008272)
0.0 1.0 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.7 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 4.2 GO:0008033 tRNA processing(GO:0008033)
0.0 0.5 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.3 GO:0050957 equilibrioception(GO:0050957)
0.0 1.4 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 1.9 GO:0043473 pigmentation(GO:0043473)
0.0 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0 0.9 GO:0016239 positive regulation of macroautophagy(GO:0016239) positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0 0.6 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.4 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 1.0 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 3.3 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 1.8 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.0 1.2 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.4 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.4 GO:0015992 proton transport(GO:0015992)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 3.2 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.0 0.0 GO:0045991 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite activation of transcription(GO:0045991) positive regulation of transcription by glucose(GO:0046016)
0.0 1.0 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.8 GO:0007569 cell aging(GO:0007569)
0.0 2.4 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 1.0 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.8 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.9 GO:0015698 inorganic anion transport(GO:0015698)
0.0 0.4 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.4 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 25.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
2.7 8.2 GO:0070195 growth hormone receptor complex(GO:0070195)
2.2 19.7 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
1.9 24.2 GO:0097418 neurofibrillary tangle(GO:0097418)
1.9 22.3 GO:0042612 MHC class I protein complex(GO:0042612)
1.6 6.4 GO:0060187 cell pole(GO:0060187)
1.1 3.2 GO:0005608 laminin-3 complex(GO:0005608)
1.0 3.1 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.9 6.0 GO:1990597 AIP1-IRE1 complex(GO:1990597) IRE1-TRAF2-ASK1 complex(GO:1990604)
0.8 2.5 GO:0005899 insulin receptor complex(GO:0005899)
0.8 2.3 GO:0032010 phagolysosome(GO:0032010)
0.7 9.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.6 1.9 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.6 12.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.6 4.9 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.6 7.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.6 2.8 GO:0043202 lysosomal lumen(GO:0043202)
0.5 1.5 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.5 9.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.5 1.9 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.5 3.3 GO:0005827 polar microtubule(GO:0005827)
0.4 9.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.4 1.7 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.4 6.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.4 2.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.3 1.6 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.3 1.6 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.3 1.2 GO:0044307 dendritic branch(GO:0044307)
0.3 3.3 GO:0016011 dystroglycan complex(GO:0016011)
0.3 7.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.3 1.7 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.3 11.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.3 0.8 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.2 2.2 GO:0005883 neurofilament(GO:0005883)
0.2 2.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2 1.9 GO:1990357 terminal web(GO:1990357)
0.2 3.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 1.8 GO:0042825 TAP complex(GO:0042825)
0.2 4.8 GO:0031528 microvillus membrane(GO:0031528)
0.2 1.0 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.2 2.3 GO:0000812 Swr1 complex(GO:0000812)
0.2 1.8 GO:0030478 actin cap(GO:0030478)
0.2 0.6 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 2.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 1.8 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.2 1.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 1.0 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 1.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 1.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 2.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.9 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.7 GO:0072487 MSL complex(GO:0072487)
0.1 0.4 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 0.6 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.1 6.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 2.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 4.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 3.3 GO:0043218 compact myelin(GO:0043218)
0.1 0.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 2.1 GO:0043034 costamere(GO:0043034)
0.1 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.0 GO:0016342 catenin complex(GO:0016342)
0.1 0.9 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.1 GO:0019034 viral replication complex(GO:0019034)
0.1 2.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.5 GO:0030057 desmosome(GO:0030057)
0.1 0.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.7 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.9 GO:0097386 glial cell projection(GO:0097386)
0.1 1.0 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 3.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.5 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.4 GO:1902710 GABA receptor complex(GO:1902710)
0.1 2.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.5 GO:0005652 nuclear lamina(GO:0005652)
0.1 1.0 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.3 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.3 GO:0005745 m-AAA complex(GO:0005745)
0.1 2.1 GO:0045095 keratin filament(GO:0045095)
0.1 6.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.5 GO:0000145 exocyst(GO:0000145)
0.1 2.1 GO:0060077 inhibitory synapse(GO:0060077)
0.1 3.3 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.5 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 1.4 GO:0010369 chromocenter(GO:0010369)
0.1 2.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 2.5 GO:0035861 site of double-strand break(GO:0035861)
0.1 2.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 5.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 0.5 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 1.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.1 3.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.4 GO:0000152 nuclear ubiquitin ligase complex(GO:0000152)
0.0 0.6 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 2.2 GO:0005882 intermediate filament(GO:0005882)
0.0 8.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 3.2 GO:0031526 brush border membrane(GO:0031526)
0.0 8.8 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 4.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0061700 Seh1-associated complex(GO:0035859) GATOR2 complex(GO:0061700)
0.0 10.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.9 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:0042629 mast cell granule(GO:0042629)
0.0 15.5 GO:0005740 mitochondrial envelope(GO:0005740)
0.0 7.0 GO:0043235 receptor complex(GO:0043235)
0.0 0.1 GO:0005713 recombination nodule(GO:0005713)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.9 GO:0005902 microvillus(GO:0005902)
0.0 2.0 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.1 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 1.1 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.0 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.8 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0097512 cardiac myofibril(GO:0097512)
0.0 2.2 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0097546 ciliary base(GO:0097546)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 21.3 GO:0005009 insulin-activated receptor activity(GO:0005009) pheromone activity(GO:0005186)
2.7 8.2 GO:0004903 growth hormone receptor activity(GO:0004903)
2.0 6.1 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
2.0 14.0 GO:0099609 microtubule lateral binding(GO:0099609)
1.9 24.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
1.8 17.5 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
1.6 4.8 GO:0045159 myosin II binding(GO:0045159)
1.3 10.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
1.3 6.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
1.2 3.7 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
1.2 3.6 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
1.2 8.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.2 5.8 GO:0008142 oxysterol binding(GO:0008142)
1.0 5.2 GO:0032810 sterol response element binding(GO:0032810)
1.0 3.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
1.0 7.0 GO:0042289 MHC class II protein binding(GO:0042289)
1.0 23.1 GO:0005550 pheromone binding(GO:0005550)
0.8 5.7 GO:0002054 nucleobase binding(GO:0002054) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.8 3.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.8 18.3 GO:0051787 misfolded protein binding(GO:0051787)
0.7 13.5 GO:0042166 acetylcholine binding(GO:0042166)
0.7 9.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.7 10.0 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.7 2.8 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.7 4.0 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.6 4.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.6 12.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.6 2.5 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.6 22.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.6 3.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.6 3.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.6 1.8 GO:0005110 frizzled-2 binding(GO:0005110)
0.6 1.7 GO:0030350 iron-responsive element binding(GO:0030350) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.6 3.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.6 4.4 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.5 2.2 GO:0015232 heme transporter activity(GO:0015232)
0.5 1.5 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.5 2.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.5 1.4 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.5 2.3 GO:0042895 antibiotic transporter activity(GO:0042895)
0.4 2.2 GO:2001070 starch binding(GO:2001070)
0.4 2.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.4 2.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.4 2.5 GO:0004528 phosphodiesterase I activity(GO:0004528) NADH pyrophosphatase activity(GO:0035529)
0.4 1.7 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.4 1.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.4 2.8 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.4 1.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.4 2.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.4 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.4 6.0 GO:0044548 S100 protein binding(GO:0044548)
0.4 1.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.4 1.8 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.4 3.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.4 3.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.3 1.0 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.3 2.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.3 1.7 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3 12.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 1.0 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.3 1.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.3 1.2 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.3 14.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.3 2.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.3 1.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.3 2.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.3 1.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.3 5.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.3 4.0 GO:0015245 fatty acid transporter activity(GO:0015245)
0.3 3.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.3 1.3 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.2 4.0 GO:0001972 retinoic acid binding(GO:0001972)
0.2 1.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 7.4 GO:0071949 FAD binding(GO:0071949)
0.2 0.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 14.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 1.7 GO:0039706 co-receptor binding(GO:0039706)
0.2 1.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.2 0.9 GO:0004645 phosphorylase activity(GO:0004645)
0.2 4.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 0.8 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.2 2.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 1.4 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 2.8 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.2 1.0 GO:0004966 galanin receptor activity(GO:0004966)
0.2 1.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 2.7 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.2 0.8 GO:0005113 patched binding(GO:0005113)
0.2 3.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 1.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.2 4.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 5.7 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.2 1.7 GO:0031404 chloride ion binding(GO:0031404)
0.2 7.6 GO:0071837 HMG box domain binding(GO:0071837)
0.2 0.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 1.6 GO:0043237 laminin-1 binding(GO:0043237)
0.2 3.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 3.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 1.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 2.2 GO:0042301 phosphate ion binding(GO:0042301)
0.2 3.4 GO:0042605 peptide antigen binding(GO:0042605)
0.2 0.8 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.2 3.9 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.2 5.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.2 0.9 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.2 2.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 1.1 GO:0032027 myosin light chain binding(GO:0032027)
0.1 3.0 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 3.7 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 5.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 2.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 1.5 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.6 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.9 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.8 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 3.9 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 1.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 2.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 1.2 GO:1901612 cardiolipin binding(GO:1901612)
0.1 1.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.8 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 3.0 GO:1905030 voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 2.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 2.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.2 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 1.9 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.1 0.9 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.5 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 1.8 GO:0070628 proteasome binding(GO:0070628)
0.1 2.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 8.2 GO:0005507 copper ion binding(GO:0005507)
0.1 0.6 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 3.9 GO:0005504 fatty acid binding(GO:0005504)
0.1 2.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 2.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 2.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 2.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.2 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 2.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 2.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 3.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.5 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 2.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.3 GO:0051431 histone deacetylase regulator activity(GO:0035033) corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 1.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 5.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.5 GO:0097643 amylin receptor activity(GO:0097643)
0.1 1.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.7 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.7 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 0.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 2.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.3 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.5 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.1 0.8 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 0.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 1.5 GO:0032183 SUMO binding(GO:0032183)
0.1 3.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 16.4 GO:0008168 methyltransferase activity(GO:0008168)
0.1 1.0 GO:0030955 potassium ion binding(GO:0030955)
0.1 5.2 GO:0002039 p53 binding(GO:0002039)
0.1 0.6 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 2.0 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 2.1 GO:0043274 phospholipase binding(GO:0043274)
0.1 1.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.4 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 18.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 0.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.9 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 0.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.5 GO:0009374 biotin binding(GO:0009374)
0.1 0.7 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 3.0 GO:0019213 deacetylase activity(GO:0019213)
0.1 1.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.7 GO:0070402 NADPH binding(GO:0070402)
0.1 0.8 GO:0015250 water channel activity(GO:0015250)
0.1 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 1.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.9 GO:0030332 cyclin binding(GO:0030332)
0.0 1.3 GO:0015295 solute:proton symporter activity(GO:0015295)
0.0 0.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237) extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 1.6 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.4 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.6 GO:0046030 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 2.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.1 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.0 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.5 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0071074 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024) transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 2.1 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 1.0 GO:0000049 tRNA binding(GO:0000049)
0.0 1.4 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.9 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 6.9 GO:0045296 cadherin binding(GO:0045296)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 4.5 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 1.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.6 GO:0030276 clathrin binding(GO:0030276)
0.0 0.9 GO:0008080 N-acetyltransferase activity(GO:0008080)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 14.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.5 9.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.4 3.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.4 22.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.4 21.2 PID IGF1 PATHWAY IGF1 pathway
0.4 16.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.4 2.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 5.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.2 7.6 PID IL1 PATHWAY IL1-mediated signaling events
0.2 10.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 6.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 10.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.2 1.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 2.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 2.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 9.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 5.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 3.2 ST ADRENERGIC Adrenergic Pathway
0.1 1.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 3.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 5.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 1.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 0.4 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 1.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 0.4 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 2.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.4 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 1.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 3.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.3 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 6.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID SHP2 PATHWAY SHP2 signaling
0.0 0.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.3 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.5 PID IL4 2PATHWAY IL4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 1.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
1.0 29.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.0 12.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.0 13.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.7 6.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.6 5.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.6 11.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 9.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.5 19.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 5.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.4 8.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.4 4.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.4 8.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.4 34.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 3.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.3 4.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 5.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.3 4.6 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.3 4.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 2.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 3.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 3.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.2 7.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2 3.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.2 1.9 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 8.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 2.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 2.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.2 1.2 REACTOME SIGNALLING BY NGF Genes involved in Signalling by NGF
0.2 3.6 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.2 1.3 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.2 3.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 3.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 5.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 2.5 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 1.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 3.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 4.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.9 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 7.1 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.1 1.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 2.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 2.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 6.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 0.6 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 0.6 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 0.2 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 2.1 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.7 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 3.8 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.1 2.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 5.4 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 0.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 1.6 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 9.0 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 1.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 2.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.2 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 2.4 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 8.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.7 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.6 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 2.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 1.0 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 2.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes