ISMARA results: Myog

Project

GSE58827: Dynamics of the Mouse Liver

Navigation

Downloads

Results for Myog_Tcf12

Z-value: 1.35

Motif logo

Transcription factors associated with Myog_Tcf12

Gene Symbol	Gene ID	Gene Info
Myog Ensembl NCBI MGI UniProt	ENSMUSG00000026459.4	myogenin
Tcf12 Ensembl NCBI MGI UniProt	ENSMUSG00000032228.10	transcription factor 12

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Tcf12	mm10_v2_chr9_-_72111827_72111895	0.57	2.8e-04	Click!
Myog	mm10_v2_chr1_+_134289997_134290015	0.54	6.2e-04	Click!

Activity profile of Myog_Tcf12 motif

Sorted Z-values of Myog_Tcf12 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr14_-_20269162 Show fit	13.36	ENSMUST00000024155.7	Kcnk16 Ensembl NCBI MGI UniProt Show fit	potassium channel, subfamily K, member 16
chr5_-_107726017 Show fit	12.76	ENSMUST00000159263.2	Gfi1 Ensembl NCBI MGI UniProt Show fit	growth factor independent 1
chr12_+_109459843 Show fit	12.46	ENSMUST00000173812.1	Dlk1 Ensembl NCBI MGI UniProt Show fit	delta-like 1 homolog (Drosophila)
chr2_-_170406501 Show fit	11.39	ENSMUST00000154650.1	Bcas1 Ensembl NCBI MGI UniProt Show fit	breast carcinoma amplified sequence 1
chr8_+_23139064 Show fit	10.38	ENSMUST00000033947.8	Ank1 Ensembl NCBI MGI UniProt Show fit	ankyrin 1, erythroid
chr2_+_84734050 Show fit	10.29	ENSMUST00000090729.2	Ypel4 Ensembl NCBI MGI UniProt Show fit	yippee-like 4 (Drosophila)
chr8_+_23139030 Show fit	9.40	ENSMUST00000121075.1	Ank1 Ensembl NCBI MGI UniProt Show fit	ankyrin 1, erythroid
chr1_-_75133866 Show fit	9.09	ENSMUST00000027405.4	Slc23a3 Ensembl NCBI MGI UniProt Show fit	solute carrier family 23 (nucleobase transporters), member 3
chr1_-_75506331 Show fit	8.72	ENSMUST00000113567.2 ENSMUST00000113565.2	Obsl1 Ensembl NCBI MGI UniProt Show fit	obscurin-like 1
chr1_+_75507077 Show fit	8.72	ENSMUST00000037330.4	Inha Ensembl NCBI MGI UniProt Show fit	inhibin alpha

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Myog_Tcf12

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	27.8	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779)
1.1	18.2	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
1.9	16.9	GO:0036309	protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.1	16.4	GO:0030322	stabilization of membrane potential(GO:0030322)
0.3	15.9	GO:0003009	skeletal muscle contraction(GO:0003009)
5.1	15.3	GO:0035702	monocyte homeostasis(GO:0035702)
2.6	12.8	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.4	12.4	GO:0046852	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1	10.0	GO:0042100	B cell proliferation(GO:0042100)
1.7	8.7	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)

Showing 1 to 10 of 366 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	33.6	GO:0031430	M band(GO:0031430)
1.2	28.3	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.2	18.0	GO:0016363	nuclear matrix(GO:0016363)
0.0	16.6	GO:0009986	cell surface(GO:0009986)
0.9	15.8	GO:0005861	troponin complex(GO:0005861)
0.4	11.8	GO:0031672	A band(GO:0031672)
0.1	10.3	GO:0072562	blood microparticle(GO:0072562)
2.9	8.7	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.8	8.6	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	8.6	GO:0005819	spindle(GO:0005819)

Showing 1 to 10 of 144 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	22.0	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
1.0	18.2	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	16.6	GO:0004896	cytokine receptor activity(GO:0004896)
1.0	16.4	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.3	15.4	GO:0030507	spectrin binding(GO:0030507)
0.4	14.1	GO:0030506	ankyrin binding(GO:0030506)
0.1	12.9	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3	11.8	GO:0003785	actin monomer binding(GO:0003785)
1.1	11.3	GO:0031014	troponin T binding(GO:0031014)
1.2	10.5	GO:0034711	inhibin binding(GO:0034711)

Showing 1 to 10 of 228 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	18.1	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.2	14.4	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.2	11.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.3	11.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.2	9.4	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.2	7.7	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.2	7.5	PID ILK PATHWAY	Integrin-linked kinase signaling
0.2	7.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.2	7.0	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.4	6.8	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway

Showing 1 to 10 of 55 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	30.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.5	27.9	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.3	14.3	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.4	13.9	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
1.0	12.5	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.2	10.9	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.2	10.0	REACTOME G1 PHASE	Genes involved in G1 Phase
0.2	9.9	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	8.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	7.9	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere

Showing 1 to 10 of 81 entries

Results for Myog_Tcf12

Z-value: 1.35

Motif logo

Transcription factors associated with Myog_Tcf12

Activity-expression correlation:

Activity profile of Myog_Tcf12 motif

Sorted Z-values of Myog_Tcf12 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Myog_Tcf12

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: