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GSE58827: Dynamics of the Mouse Liver

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Results for Nkx2-4

Z-value: 0.58

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Transcription factors associated with Nkx2-4

Gene Symbol Gene ID Gene Info
Nkx2-4
ENSMUSG00000054160.2 NK2 homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx2-4mm10_v2_chr2_-_147085445_1470854830.316.4e-02Click!

Activity profile of Nkx2-4 motif

Sorted Z-values of Nkx2-4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_41354105 4.00 ENSMUST00000072103.5
Try10
trypsin 10
chr3_-_92588982 3.76 ENSMUST00000098888.5
Smcp
sperm mitochondria-associated cysteine-rich protein
chr6_-_122609964 1.48 ENSMUST00000032211.4
Gdf3
growth differentiation factor 3
chr2_+_131950855 1.21 ENSMUST00000110170.1
ENSMUST00000110172.2
ENSMUST00000110171.2
Prnd
prion protein dublet
chr13_+_108316395 1.16 ENSMUST00000171178.1
Depdc1b
DEP domain containing 1B
chr14_-_47418407 1.15 ENSMUST00000043296.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr19_-_39886730 1.14 ENSMUST00000168838.1
Cyp2c69
cytochrome P450, family 2, subfamily c, polypeptide 69
chr7_-_81566939 1.13 ENSMUST00000042318.5
Fsd2
fibronectin type III and SPRY domain containing 2
chr17_-_57194170 1.13 ENSMUST00000005976.6
Tnfsf14
tumor necrosis factor (ligand) superfamily, member 14
chr3_+_153844209 1.11 ENSMUST00000044089.3
Asb17
ankyrin repeat and SOCS box-containing 17
chr6_+_134929118 1.00 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5
RP23-45G16.5
chr3_-_10301169 0.99 ENSMUST00000119761.1
ENSMUST00000029043.6
Fabp12
fatty acid binding protein 12
chr10_+_20347788 0.98 ENSMUST00000169712.1
Mtfr2
mitochondrial fission regulator 2
chr11_+_110968056 0.90 ENSMUST00000125692.1
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr6_+_134929089 0.88 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5
RP23-45G16.5
chr15_-_26895049 0.85 ENSMUST00000059204.9
Fbxl7
F-box and leucine-rich repeat protein 7
chr1_+_174158722 0.80 ENSMUST00000068403.3
Olfr420
olfactory receptor 420
chr12_+_111406809 0.79 ENSMUST00000150384.1
A230065H16Rik
RIKEN cDNA A230065H16 gene
chr3_+_88629499 0.79 ENSMUST00000175745.1
Arhgef2
rho/rac guanine nucleotide exchange factor (GEF) 2
chr15_-_100669512 0.70 ENSMUST00000182574.1
ENSMUST00000182775.1
Bin2
bridging integrator 2
chr7_-_132813095 0.70 ENSMUST00000106165.1
Fam53b
family with sequence similarity 53, member B
chr15_-_100669535 0.67 ENSMUST00000183211.1
Bin2
bridging integrator 2
chr6_+_29398920 0.67 ENSMUST00000181464.1
ENSMUST00000180829.1
Ccdc136
coiled-coil domain containing 136
chr15_-_100669496 0.66 ENSMUST00000182814.1
ENSMUST00000182068.1
Bin2
bridging integrator 2
chr6_-_98342728 0.64 ENSMUST00000164491.1
Gm765
predicted gene 765
chr7_-_100932140 0.63 ENSMUST00000107032.1
Arhgef17
Rho guanine nucleotide exchange factor (GEF) 17
chr17_+_6689072 0.59 ENSMUST00000160483.1
Sytl3
synaptotagmin-like 3
chr5_+_89028035 0.58 ENSMUST00000113216.2
ENSMUST00000134303.1
Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr9_+_108560422 0.55 ENSMUST00000081111.8
Impdh2
inosine 5'-phosphate dehydrogenase 2
chr5_+_89027959 0.51 ENSMUST00000130041.1
Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr9_-_71896047 0.50 ENSMUST00000184448.1
Tcf12
transcription factor 12
chr2_+_156840966 0.49 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr13_-_105271039 0.48 ENSMUST00000069686.6
Rnf180
ring finger protein 180
chr3_-_110250963 0.48 ENSMUST00000106567.1
Prmt6
protein arginine N-methyltransferase 6
chr10_+_128232065 0.47 ENSMUST00000055539.4
ENSMUST00000105244.1
ENSMUST00000105243.2
ENSMUST00000125289.1
ENSMUST00000105242.1
Timeless
timeless circadian clock 1
chr11_+_70026815 0.45 ENSMUST00000135916.2
Dlg4
discs, large homolog 4 (Drosophila)
chr15_+_103009479 0.45 ENSMUST00000001711.4
Hoxc6
homeobox C6
chr15_+_66670749 0.44 ENSMUST00000065916.7
Tg
thyroglobulin
chr13_+_108860072 0.43 ENSMUST00000177907.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr19_-_39812744 0.43 ENSMUST00000162507.1
ENSMUST00000160476.1
Cyp2c40
cytochrome P450, family 2, subfamily c, polypeptide 40
chr5_-_64932761 0.43 ENSMUST00000059349.4
Tlr1
toll-like receptor 1
chr13_-_66852017 0.42 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr2_-_93046053 0.42 ENSMUST00000111272.1
ENSMUST00000178666.1
ENSMUST00000147339.1
Prdm11
PR domain containing 11
chr1_+_85649988 0.42 ENSMUST00000155094.1
Sp100
nuclear antigen Sp100
chr5_-_120749848 0.42 ENSMUST00000053909.6
ENSMUST00000081491.6
Oas2
2'-5' oligoadenylate synthetase 2
chr1_+_85650008 0.41 ENSMUST00000054279.8
ENSMUST00000147552.1
ENSMUST00000153574.1
ENSMUST00000150967.1
Sp100
nuclear antigen Sp100
chr2_+_157456917 0.41 ENSMUST00000109529.1
Src
Rous sarcoma oncogene
chr11_+_101733011 0.40 ENSMUST00000129741.1
Dhx8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr13_+_65512678 0.40 ENSMUST00000081471.2
Gm10139
predicted gene 10139
chr7_+_128129536 0.38 ENSMUST00000033053.6
Itgax
integrin alpha X
chr2_-_147186389 0.35 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2
NK2 homeobox 2
chr2_+_174643534 0.35 ENSMUST00000059452.5
Zfp831
zinc finger protein 831
chr15_-_98898483 0.35 ENSMUST00000023737.4
Dhh
desert hedgehog
chr6_+_123229843 0.33 ENSMUST00000112554.2
ENSMUST00000024118.4
ENSMUST00000117130.1
Clec4n
C-type lectin domain family 4, member n
chr19_-_39649046 0.33 ENSMUST00000067328.6
Cyp2c67
cytochrome P450, family 2, subfamily c, polypeptide 67
chr3_-_59220150 0.33 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr5_+_34999111 0.30 ENSMUST00000114283.1
Rgs12
regulator of G-protein signaling 12
chr7_-_34812677 0.29 ENSMUST00000078686.6
Chst8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr2_-_85035487 0.27 ENSMUST00000028465.7
P2rx3
purinergic receptor P2X, ligand-gated ion channel, 3
chr7_-_115824699 0.27 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr17_-_51832666 0.25 ENSMUST00000144331.1
Satb1
special AT-rich sequence binding protein 1
chr11_+_101732950 0.25 ENSMUST00000039152.7
Dhx8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr8_-_40308331 0.25 ENSMUST00000118639.1
Fgf20
fibroblast growth factor 20
chr10_-_26373956 0.23 ENSMUST00000105519.3
ENSMUST00000040219.6
L3mbtl3
l(3)mbt-like 3 (Drosophila)
chr1_-_37536232 0.22 ENSMUST00000042161.8
Mgat4a
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr1_+_85650044 0.21 ENSMUST00000066427.4
Sp100
nuclear antigen Sp100
chr9_-_58158498 0.21 ENSMUST00000168864.2
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr14_+_26514554 0.19 ENSMUST00000104927.1
Gm2178
predicted gene 2178
chr19_-_45742873 0.18 ENSMUST00000026241.5
ENSMUST00000026240.7
ENSMUST00000111928.1
Fgf8
fibroblast growth factor 8
chrX_+_107089234 0.17 ENSMUST00000118666.1
ENSMUST00000053375.3
P2ry10
purinergic receptor P2Y, G-protein coupled 10
chrX_+_56447965 0.17 ENSMUST00000079663.6
Gm2174
predicted gene 2174
chr12_+_105685352 0.17 ENSMUST00000051934.5
Gskip
GSK3B interacting protein
chrX_+_112604274 0.16 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chr15_+_54410755 0.14 ENSMUST00000036737.3
Colec10
collectin sub-family member 10
chr12_+_38781093 0.14 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr7_-_80905060 0.13 ENSMUST00000119428.1
ENSMUST00000026817.4
Nmb
neuromedin B
chr2_-_170497141 0.12 ENSMUST00000038824.5
Cyp24a1
cytochrome P450, family 24, subfamily a, polypeptide 1
chr6_+_21986438 0.12 ENSMUST00000115382.1
Cped1
cadherin-like and PC-esterase domain containing 1
chr4_+_48663502 0.09 ENSMUST00000030033.4
Murc
muscle-related coiled-coil protein
chr6_-_91807424 0.09 ENSMUST00000162300.1
Grip2
glutamate receptor interacting protein 2
chr15_+_99670574 0.09 ENSMUST00000023758.7
Asic1
acid-sensing (proton-gated) ion channel 1
chr3_-_108200807 0.09 ENSMUST00000106655.1
ENSMUST00000065664.6
Cyb561d1
cytochrome b-561 domain containing 1
chr2_-_85196697 0.09 ENSMUST00000099930.2
ENSMUST00000111601.1
Lrrc55
leucine rich repeat containing 55
chr9_-_52679429 0.08 ENSMUST00000098768.2
AI593442
expressed sequence AI593442
chr2_+_25180737 0.07 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr5_+_32136458 0.07 ENSMUST00000031017.9
Fosl2
fos-like antigen 2
chr3_+_96696379 0.06 ENSMUST00000107076.3
Pias3
protein inhibitor of activated STAT 3
chr15_+_99055164 0.06 ENSMUST00000047104.7
ENSMUST00000024249.3
Prph
peripherin
chr18_+_43963234 0.05 ENSMUST00000069245.7
Spink5
serine peptidase inhibitor, Kazal type 5
chr12_+_87954475 0.05 ENSMUST00000181843.1
ENSMUST00000180706.1
ENSMUST00000181394.1
ENSMUST00000110145.4
ENSMUST00000181326.1
ENSMUST00000181300.1
Gm2042
predicted gene 2042
chr11_+_49247462 0.05 ENSMUST00000109194.1
Mgat1
mannoside acetylglucosaminyltransferase 1
chr12_+_69963452 0.05 ENSMUST00000110560.1
Gm3086
predicted gene 3086
chr17_+_16972910 0.04 ENSMUST00000071374.5
BC002059
cDNA sequence BC002059
chr12_+_38780817 0.04 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr1_-_34439672 0.04 ENSMUST00000042493.8
Ccdc115
coiled-coil domain containing 115
chr8_+_45627946 0.03 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chr11_+_110968016 0.03 ENSMUST00000106636.1
ENSMUST00000180023.1
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr8_+_11556061 0.02 ENSMUST00000054399.4
Ing1
inhibitor of growth family, member 1
chr7_+_82867327 0.02 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr12_+_87954080 0.01 ENSMUST00000180803.1
ENSMUST00000180707.1
ENSMUST00000181347.1
Gm2042
predicted gene 2042
chr4_+_62525369 0.01 ENSMUST00000062145.1
4933430I17Rik
RIKEN cDNA 4933430I17 gene
chr8_+_45628176 0.01 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chrX_-_73115363 0.01 ENSMUST00000114520.1
Xlr5a
X-linked lymphocyte-regulated 5A
chr5_-_137533297 0.01 ENSMUST00000111020.1
ENSMUST00000111023.1
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr1_-_181853183 0.01 ENSMUST00000070987.7
Gm5533
predicted gene 5533
chr10_+_88091070 0.01 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr8_+_46490968 0.01 ENSMUST00000110372.1
ENSMUST00000130563.1
Acsl1
acyl-CoA synthetase long-chain family member 1
chr19_-_39740999 0.01 ENSMUST00000099472.3
Cyp2c68
cytochrome P450, family 2, subfamily c, polypeptide 68
chr11_-_53859187 0.01 ENSMUST00000117316.1
ENSMUST00000120776.1
ENSMUST00000121435.1
Gm12216
predicted gene 12216
chr1_+_106938953 0.00 ENSMUST00000112724.2
Serpinb12
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12
chr16_+_32419696 0.00 ENSMUST00000014220.8
ENSMUST00000080316.7
Tctex1d2
Tctex1 domain containing 2
chr2_-_34755229 0.00 ENSMUST00000102800.1
Gapvd1
GTPase activating protein and VPS9 domains 1
chr11_-_103697661 0.00 ENSMUST00000107013.2
Gosr2
golgi SNAP receptor complex member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx2-4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.8 GO:0007341 penetration of zona pellucida(GO:0007341)
0.4 1.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2 0.3 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.2 0.5 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.1 1.5 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.4 GO:0070340 detection of bacterial lipopeptide(GO:0070340) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.5 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.4 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.8 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.3 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.4 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.1 0.3 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 2.0 GO:0097320 membrane tubulation(GO:0097320)
0.1 0.3 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 1.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 1.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.1 0.3 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.0 0.4 GO:0015705 iodide transport(GO:0015705)
0.0 1.1 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.4 GO:0098953 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 0.7 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.4 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 4.0 GO:0007586 digestion(GO:0007586)
0.0 0.5 GO:0042428 serotonin metabolic process(GO:0042428)
0.0 0.9 GO:0010107 potassium ion import(GO:0010107)
0.0 0.9 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.5 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0002784 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 1.0 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.8 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 1.9 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.0 0.2 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0033280 response to vitamin D(GO:0033280)
0.0 0.3 GO:0050832 defense response to fungus(GO:0050832)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 GO:0002102 podosome(GO:0002102)
0.1 1.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 4.0 GO:0072562 blood microparticle(GO:0072562)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.7 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.3 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 3.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.1 GO:0044299 C-fiber(GO:0044299)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 1.3 GO:0016605 PML body(GO:0016605)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 0.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.5 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 0.3 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1 0.4 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 1.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.9 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.3 GO:0005113 patched binding(GO:0005113)
0.0 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 1.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 4.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 1.2 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID AURORA A PATHWAY Aurora A signaling
0.0 0.5 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events