Project

GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Nr1h2

Z-value: 0.94

Motif logo

Transcription factors associated with Nr1h2

Gene Symbol Gene ID Gene Info
ENSMUSG00000060601.6 nuclear receptor subfamily 1, group H, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr1h2mm10_v2_chr7_-_44553901_44553955-0.473.9e-03Click!

Activity profile of Nr1h2 motif

Sorted Z-values of Nr1h2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_97417730 14.73 ENSMUST00000043077.7
thyroid hormone responsive
chr2_+_102658640 7.28 ENSMUST00000080210.3
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr15_+_82452372 4.97 ENSMUST00000089129.5
cytochrome P450, family 2, subfamily d, polypeptide 9
chr19_-_46672883 4.00 ENSMUST00000026012.7
cytochrome P450, family 17, subfamily a, polypeptide 1
chr15_+_82555087 3.99 ENSMUST00000068861.6
cytochrome P450, family 2, subfamily d, polypeptide 12
chr6_+_125320633 3.79 ENSMUST00000176655.1
ENSMUST00000176110.1
sodium channel, nonvoltage-gated 1 alpha
chr3_+_146597077 3.64 ENSMUST00000029837.7
ENSMUST00000121133.1
urate oxidase
chr4_+_43641262 3.58 ENSMUST00000123351.1
ENSMUST00000128549.1
natriuretic peptide receptor 2
chr11_+_55098104 3.35 ENSMUST00000000608.7
GM2 ganglioside activator protein
chr6_-_119544282 3.22 ENSMUST00000119369.1
ENSMUST00000178696.1
wingless-related MMTV integration site 5B
chr17_-_83846769 3.15 ENSMUST00000000687.7
3-hydroxyanthranilate 3,4-dioxygenase
chr17_+_24804312 2.77 ENSMUST00000024972.5
meiosis specific with OB domains
chr1_-_139560158 2.74 ENSMUST00000160423.1
ENSMUST00000023965.5
complement factor H-related 1
chr16_+_13940630 2.72 ENSMUST00000141971.1
ENSMUST00000124947.1
ENSMUST00000023360.7
ENSMUST00000143697.1
Mpv17 transgene, kidney disease mutant-like
chr11_-_60210410 2.47 ENSMUST00000144942.1
sterol regulatory element binding transcription factor 1
chr3_+_62419668 2.39 ENSMUST00000161057.1
Rho guanine nucleotide exchange factor (GEF) 26
chr13_-_12461432 2.32 ENSMUST00000143693.1
ENSMUST00000144283.1
ENSMUST00000099820.3
ENSMUST00000135166.1
lectin, galactose binding, soluble 8
chr2_+_155382186 2.29 ENSMUST00000134218.1
transformation related protein 53 inducible nuclear protein 2
chr3_-_146596588 2.24 ENSMUST00000029836.4
deoxyribonuclease II beta
chr8_-_70632419 2.24 ENSMUST00000110103.1
growth differentiation factor 15
chr11_+_84179852 2.04 ENSMUST00000136463.2
acetyl-Coenzyme A carboxylase alpha
chr2_+_155381808 1.86 ENSMUST00000043237.7
ENSMUST00000174685.1
transformation related protein 53 inducible nuclear protein 2
chr9_+_77941274 1.83 ENSMUST00000134072.1
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr9_+_46240696 1.80 ENSMUST00000034585.6
apolipoprotein A-IV
chr8_-_106136792 1.78 ENSMUST00000146940.1
epithelial splicing regulatory protein 2
chr6_+_90462562 1.77 ENSMUST00000032174.5
Kruppel-like factor 15
chr11_+_84179792 1.75 ENSMUST00000137500.2
ENSMUST00000130012.2
acetyl-Coenzyme A carboxylase alpha
chr3_-_138186700 1.74 ENSMUST00000012186.4
RIKEN cDNA 4930579F01 gene
chrX_+_10717390 1.72 ENSMUST00000115524.1
ENSMUST00000008179.6
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chrX_+_10717451 1.66 ENSMUST00000156321.1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr2_+_30266721 1.64 ENSMUST00000113645.1
ENSMUST00000133877.1
ENSMUST00000139719.1
ENSMUST00000113643.1
ENSMUST00000150695.1
phytanoyl-CoA dioxygenase domain containing 1
chr8_-_106136890 1.62 ENSMUST00000115979.2
epithelial splicing regulatory protein 2
chr7_-_118705708 1.60 ENSMUST00000038791.8
glycerophosphodiester phosphodiesterase 1
chr2_-_157571270 1.58 ENSMUST00000173378.1
bladder cancer associated protein homolog (human)
chr2_+_155276297 1.58 ENSMUST00000029128.3
microtubule-associated protein 1 light chain 3 alpha
chr14_+_54968781 1.57 ENSMUST00000181782.1
RIKEN cDNA D830015G02 gene
chr16_+_96205719 1.57 ENSMUST00000129904.1
SH3-binding domain glutamic acid-rich protein
chr8_-_84773381 1.54 ENSMUST00000109764.1
nuclear factor I/X
chr2_-_26604267 1.48 ENSMUST00000028286.5
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr1_+_78657825 1.48 ENSMUST00000035779.8
acyl-CoA synthetase long-chain family member 3
chr17_-_35897073 1.47 ENSMUST00000150056.1
ENSMUST00000156817.1
ENSMUST00000146451.1
ENSMUST00000148482.1
RIKEN cDNA 2310061I04 gene
chr6_-_90224438 1.45 ENSMUST00000076086.2
vomeronasal 1 receptor 53
chr1_-_131276914 1.44 ENSMUST00000161764.1
inhibitor of kappaB kinase epsilon
chr1_+_78657874 1.43 ENSMUST00000134566.1
ENSMUST00000142704.1
ENSMUST00000053760.5
acyl-CoA synthetase long-chain family member 3
UTP14, U3 small nucleolar ribonucleoprotein, homolog B (yeast)
chr2_-_155834845 1.40 ENSMUST00000029143.5
family with sequence similarity 83, member C
chr3_+_90514435 1.36 ENSMUST00000048138.6
ENSMUST00000181271.1
S100 calcium binding protein A13
chr3_-_39359128 1.34 ENSMUST00000056409.2
predicted pseudogene 9845
chr2_+_30266513 1.30 ENSMUST00000091132.6
phytanoyl-CoA dioxygenase domain containing 1
chr7_-_133776681 1.30 ENSMUST00000130182.1
ENSMUST00000106139.1
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr10_-_81600857 1.25 ENSMUST00000151858.1
ENSMUST00000142948.1
ENSMUST00000072020.2
transducin-like enhancer of split 6, homolog of Drosophila E(spl)
chr1_+_57377593 1.23 ENSMUST00000042734.2
RIKEN cDNA 1700066M21 gene
chr6_+_54429603 1.21 ENSMUST00000132855.1
ENSMUST00000126637.1
WAS/WASL interacting protein family, member 3
chr5_+_107331157 1.21 ENSMUST00000031215.8
ENSMUST00000112677.3
bromodomain, testis-specific
chr16_-_37384915 1.19 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
syntaxin binding protein 5-like
chr11_-_101119814 1.16 ENSMUST00000107295.3
family with sequence similarity 134, member C
chr17_-_56716788 1.15 ENSMUST00000067931.5
vimentin-type intermediate filament associated coiled-coil protein
chr16_-_37384940 1.11 ENSMUST00000114781.1
ENSMUST00000114780.1
syntaxin binding protein 5-like
chr7_+_67647405 1.11 ENSMUST00000032774.8
ENSMUST00000107471.1
tetratricopeptide repeat domain 23
chr7_-_80371197 1.10 ENSMUST00000098346.3
mannosidase 2, alpha 2
chr10_+_18845071 1.07 ENSMUST00000019998.7
PERP, TP53 apoptosis effector
chr9_-_35199877 1.04 ENSMUST00000176021.1
ENSMUST00000176531.1
ENSMUST00000176685.1
ENSMUST00000177129.1
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
chr15_+_85832301 1.03 ENSMUST00000146088.1
tetratricopeptide repeat domain 38
chr11_-_101119889 1.01 ENSMUST00000017946.5
family with sequence similarity 134, member C
chr17_-_56218881 1.01 ENSMUST00000038794.4
dipeptidylpeptidase 9
chr4_-_42168603 0.99 ENSMUST00000098121.3
predicted gene 13305
chr15_+_65787023 0.96 ENSMUST00000015146.9
ENSMUST00000173858.1
ENSMUST00000172756.1
ENSMUST00000174856.1
EFR3 homolog A (S. cerevisiae)
chr7_+_49759100 0.96 ENSMUST00000085272.5
HIV-1 tat interactive protein 2, homolog (human)
chr2_-_65238573 0.96 ENSMUST00000090896.3
ENSMUST00000155082.1
Cobl-like 1
chr4_-_63154130 0.95 ENSMUST00000030041.4
alpha 1 microglobulin/bikunin
chr19_+_46707443 0.92 ENSMUST00000003655.7
arsenic (+3 oxidation state) methyltransferase
chr15_-_79328201 0.90 ENSMUST00000173163.1
ENSMUST00000047816.8
ENSMUST00000172403.2
ENSMUST00000173632.1
phospholipase A2, group VI
chrX_-_102644210 0.88 ENSMUST00000052012.7
ENSMUST00000043596.5
ENSMUST00000119229.1
ENSMUST00000122022.1
ENSMUST00000120270.1
ENSMUST00000113611.2
phosphorylase kinase alpha 1
chr1_-_164458345 0.86 ENSMUST00000027863.7
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr18_+_17019051 0.84 ENSMUST00000147119.1
ENSMUST00000153022.1
RIKEN cDNA 1700001G01 gene
chr7_-_78783026 0.84 ENSMUST00000032841.5
mitochondrial ribosomal protein L46
chr12_+_87147703 0.83 ENSMUST00000063117.8
glutathione transferase zeta 1 (maleylacetoacetate isomerase)
chr3_-_148989316 0.81 ENSMUST00000098518.2
latrophilin 2
chr15_-_79328154 0.81 ENSMUST00000166977.2
phospholipase A2, group VI
chr11_+_101119938 0.81 ENSMUST00000043680.8
tubulin, gamma 1
chr12_+_108792946 0.78 ENSMUST00000021692.7
YY1 transcription factor
chr1_+_33719863 0.77 ENSMUST00000088287.3
RAB23, member RAS oncogene family
chr10_+_21425342 0.76 ENSMUST00000042671.4
RIKEN cDNA 1700021A07 gene
chr13_+_55600055 0.76 ENSMUST00000133176.1
ENSMUST00000064701.6
xylosylprotein beta1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
chr1_+_58711488 0.72 ENSMUST00000097722.2
ENSMUST00000114313.1
CASP8 and FADD-like apoptosis regulator
chr1_+_131599239 0.72 ENSMUST00000027690.6
arginine vasopressin receptor 1B
chr7_+_78783119 0.71 ENSMUST00000032840.4
mitochondrial ribosomal protein S11
chr17_-_79715034 0.70 ENSMUST00000024894.1
cytochrome P450, family 1, subfamily b, polypeptide 1
chr5_+_124328083 0.70 ENSMUST00000111477.1
ENSMUST00000077376.2
RIKEN cDNA 2810006K23 gene
chr8_-_84237042 0.69 ENSMUST00000039480.5
zinc finger SWIM-type containing 4
chr19_+_42247544 0.66 ENSMUST00000122375.1
golgi autoantigen, golgin subfamily a, 7B
chr11_+_93996082 0.66 ENSMUST00000041956.7
sperm associated antigen 9
chr2_-_65238625 0.66 ENSMUST00000112429.2
ENSMUST00000102726.1
ENSMUST00000112430.1
Cobl-like 1
chr16_-_38550173 0.65 ENSMUST00000036210.6
protein O-glucosyltransferase 1
chr4_-_119422355 0.64 ENSMUST00000106316.1
ENSMUST00000030385.6
phosphopantothenoylcysteine synthetase
chr18_-_9619460 0.64 ENSMUST00000062769.6
centrin 1
chr2_-_6951680 0.63 ENSMUST00000076071.2
predicted gene 10115
chr16_+_87784075 0.61 ENSMUST00000069809.4
RIKEN cDNA 2810407A14 gene
chr11_-_30025915 0.61 ENSMUST00000058902.5
echinoderm microtubule associated protein like 6
chr5_-_122779278 0.60 ENSMUST00000111668.3
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr3_+_89245952 0.57 ENSMUST00000040888.5
keratinocyte associated protein 2
chr7_+_114768767 0.57 ENSMUST00000151464.1
inscuteable homolog (Drosophila)
chr13_-_100552442 0.56 ENSMUST00000159515.1
ENSMUST00000160859.1
ENSMUST00000069756.4
occludin
chr19_-_5845471 0.56 ENSMUST00000174287.1
ENSMUST00000173672.1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr5_-_136565432 0.55 ENSMUST00000176172.1
cut-like homeobox 1
chr5_+_117363513 0.55 ENSMUST00000111959.1
WD repeat and SOCS box-containing 2
chr12_-_87147883 0.53 ENSMUST00000037788.4
protein-O-mannosyltransferase 2
chr9_-_63399216 0.53 ENSMUST00000168665.1
RIKEN cDNA 2300009A05 gene
chr15_+_88600280 0.51 ENSMUST00000066949.7
zinc finger, DHHC domain containing 25
chr3_-_51408925 0.50 ENSMUST00000038108.6
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1
chr11_+_58963790 0.46 ENSMUST00000075141.6
tripartite motif-containing 17
chr17_+_49428359 0.46 ENSMUST00000165390.2
ENSMUST00000024797.9
ENSMUST00000173033.1
molybdenum cofactor synthesis 1
chr3_+_89246397 0.44 ENSMUST00000168900.1
keratinocyte associated protein 2
chr2_+_131210501 0.44 ENSMUST00000110206.1
adaptor-related protein 5 complex, sigma 1 subunit
chr5_+_67306941 0.43 ENSMUST00000162372.1
ENSMUST00000113676.2
solute carrier family 30 (zinc transporter), member 9
chr7_+_114768736 0.42 ENSMUST00000117543.1
inscuteable homolog (Drosophila)
chr6_+_146861798 0.40 ENSMUST00000148099.1
single-pass membrane protein with coiled-coil domains 2
chr5_-_136244865 0.39 ENSMUST00000005188.9
SH2B adaptor protein 2
chr5_+_146481943 0.39 ENSMUST00000179032.1
predicted gene 6408
chr19_+_5041337 0.39 ENSMUST00000116567.2
breast cancer metastasis-suppressor 1
chr13_+_23695791 0.39 ENSMUST00000041052.2
histone cluster 1, H1t
chr9_+_37208291 0.38 ENSMUST00000034632.8
transmembrane protein 218
chr7_+_125318334 0.36 ENSMUST00000060220.1
RIKEN cDNA 4930533L02 gene
chr6_+_124663027 0.35 ENSMUST00000004381.7
lysophosphatidylcholine acyltransferase 3
chr11_+_114091404 0.34 ENSMUST00000129365.1
RIKEN cDNA 1700025D23 gene
chr10_+_21993890 0.33 ENSMUST00000092673.4
serum/glucocorticoid regulated kinase 1
chr13_+_102693596 0.32 ENSMUST00000172138.1
CD180 antigen
chr19_+_11569447 0.31 ENSMUST00000087884.1
predicted pseudogene 10212
chr11_+_115834314 0.30 ENSMUST00000173289.1
ENSMUST00000137900.1
lethal giant larvae homolog 2 (Drosophila)
chr1_+_6214627 0.30 ENSMUST00000027040.6
RB1-inducible coiled-coil 1
chr2_+_131210363 0.30 ENSMUST00000110210.1
ENSMUST00000089506.5
ENSMUST00000110208.1
adaptor-related protein 5 complex, sigma 1 subunit
chr6_-_99632376 0.29 ENSMUST00000176255.1
predicted gene 20696
chr14_-_20730327 0.28 ENSMUST00000047490.5
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr14_+_54686171 0.28 ENSMUST00000038539.6
RIKEN cDNA 1700123O20 gene
chr5_+_31494736 0.28 ENSMUST00000076949.6
ENSMUST00000117700.1
GPN-loop GTPase 1
chr5_+_115466234 0.27 ENSMUST00000145785.1
ENSMUST00000031495.4
ENSMUST00000112071.1
ENSMUST00000125568.1
phospholipase A2, group IB, pancreas
chr12_+_105159690 0.27 ENSMUST00000085043.5
T cell leukemia/lymphoma 1B, 1
chr11_-_103697898 0.27 ENSMUST00000021329.7
golgi SNAP receptor complex member 2
chrX_-_155216444 0.26 ENSMUST00000026318.8
spermidine/spermine N1-acetyl transferase 1
chr9_+_65361049 0.26 ENSMUST00000147185.1
predicted gene 514
chrX_-_155216338 0.25 ENSMUST00000112551.3
spermidine/spermine N1-acetyl transferase 1
chr5_-_146185304 0.23 ENSMUST00000073721.5
RIKEN cDNA 1700001J03 gene
chrX_-_53608979 0.22 ENSMUST00000123034.1
predicted gene 14597
chr1_+_31176404 0.21 ENSMUST00000062560.7
lengsin, lens protein with glutamine synthetase domain
chr11_+_82952095 0.20 ENSMUST00000108158.2
ENSMUST00000067443.2
schlafen 5
chr17_+_44777127 0.20 ENSMUST00000050630.7
suppressor of Ty 3
chr1_+_38987806 0.20 ENSMUST00000027247.5
phosducin-like 3
chr17_-_25985641 0.19 ENSMUST00000041641.8
calpain 15
chr12_+_105563123 0.17 ENSMUST00000001652.5
bradykinin receptor, beta 2
chr14_-_72602945 0.17 ENSMUST00000162825.1
fibronectin type III domain containing 3A
chr5_+_123015010 0.16 ENSMUST00000121652.1
ENSMUST00000051016.4
ORAI calcium release-activated calcium modulator 1
chr10_-_60938123 0.16 ENSMUST00000036304.3
polymorphic derived intron containing
chr12_-_21286097 0.16 ENSMUST00000173729.1
integrin beta 1 binding protein 1
chr7_-_102888151 0.16 ENSMUST00000078191.2
olfactory receptor 569
chr7_-_25718976 0.16 ENSMUST00000002683.2
coiled-coil domain containing 97
chr5_-_145032764 0.16 ENSMUST00000071421.4
predicted gene 4871
chr12_-_21286176 0.14 ENSMUST00000172834.1
ENSMUST00000076260.4
integrin beta 1 binding protein 1
chr16_+_16870829 0.14 ENSMUST00000131063.1
topoisomerase (DNA) III beta
chr15_+_78877172 0.13 ENSMUST00000041587.7
golgi associated, gamma adaptin ear containing, ARF binding protein 1
chr7_-_104129792 0.13 ENSMUST00000053743.4
RIKEN cDNA 4931431F19 gene
chr5_+_130219706 0.12 ENSMUST00000065329.6
transmembrane protein 248
chr7_-_27446599 0.09 ENSMUST00000011895.7
spectrin beta, non-erythrocytic 4
chr2_+_154223737 0.09 ENSMUST00000045959.7
BPI fold containing family B, member 5
chr11_+_78245743 0.08 ENSMUST00000002133.8
stromal cell derived factor 2
chr13_+_68582213 0.07 ENSMUST00000051784.8
FAST kinase domains 3
chr4_-_46389391 0.07 ENSMUST00000086563.4
ENSMUST00000030015.5
RIKEN cDNA 5830415F09 gene
chr9_-_42472198 0.06 ENSMUST00000128959.1
ENSMUST00000066148.5
ENSMUST00000138506.1
tubulin folding cofactor E-like
chr7_-_45179539 0.06 ENSMUST00000179443.1
predicted gene 581
chr4_-_133545906 0.05 ENSMUST00000030665.6
nuclear distribution gene C homolog (Aspergillus)
chr8_+_71592158 0.03 ENSMUST00000034264.4
ENSMUST00000138742.1
ENSMUST00000143441.1
6-phosphogluconolactonase
chr8_+_18846251 0.03 ENSMUST00000149565.1
ENSMUST00000033847.4
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr5_-_17849783 0.03 ENSMUST00000170051.1
ENSMUST00000165232.1
CD36 antigen
chr5_+_117357274 0.02 ENSMUST00000031309.9
WD repeat and SOCS box-containing 2
chr2_+_180589245 0.02 ENSMUST00000029087.3
opioid growth factor receptor
chr16_+_17894197 0.01 ENSMUST00000046937.2
testis-specific serine kinase 1
chr2_-_152596436 0.01 ENSMUST00000109834.2
defensin beta 45
chr13_+_111255010 0.01 ENSMUST00000054716.3
actin, beta-like 2
chr14_+_50944499 0.00 ENSMUST00000178092.1
purine-nucleoside phosphorylase

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr1h2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 7.3 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.0 2.9 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.9 3.8 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.7 2.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.5 2.7 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.4 17.2 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.4 3.4 GO:0009313 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.4 3.1 GO:0046874 quinolinate metabolic process(GO:0046874)
0.4 2.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.4 3.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168) negative regulation of oocyte maturation(GO:1900194)
0.3 2.8 GO:0007144 female meiosis I(GO:0007144)
0.3 1.0 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.3 1.7 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of arachidonic acid secretion(GO:0090238) positive regulation of ceramide biosynthetic process(GO:2000304)
0.3 0.9 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.3 1.0 GO:2000338 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.3 0.8 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.3 2.0 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.2 0.7 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.2 0.7 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) endothelial cell-cell adhesion(GO:0071603)
0.2 1.4 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.2 4.0 GO:0042448 progesterone metabolic process(GO:0042448)
0.2 3.6 GO:0046415 urate metabolic process(GO:0046415)
0.2 5.2 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.2 0.7 GO:1903943 skeletal muscle atrophy(GO:0014732) negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 0.5 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.2 0.7 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 0.8 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.6 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 9.0 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.1 1.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 2.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 1.1 GO:0006013 mannose metabolic process(GO:0006013)
0.1 1.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 1.5 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.7 GO:0048318 protein O-linked glycosylation via serine(GO:0018242) axial mesoderm development(GO:0048318)
0.1 0.5 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 2.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 1.6 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.1 0.7 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 3.8 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.1 1.1 GO:0002934 desmosome organization(GO:0002934)
0.1 3.4 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 0.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 1.5 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 2.2 GO:1901739 regulation of myoblast fusion(GO:1901739) positive regulation of myoblast fusion(GO:1901741)
0.1 1.5 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.1 1.8 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.5 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.1 0.3 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.3 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.2 GO:0007141 male meiosis I(GO:0007141)
0.1 0.4 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.6 GO:0070673 response to interleukin-18(GO:0070673)
0.1 1.6 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.7 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 5.2 GO:0000045 autophagosome assembly(GO:0000045)
0.1 0.9 GO:0009404 toxin metabolic process(GO:0009404)
0.1 0.8 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.2 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 0.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 1.0 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 3.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 1.5 GO:0019236 response to pheromone(GO:0019236)
0.0 0.4 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 2.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.8 GO:0097435 fibril organization(GO:0097435)
0.0 0.2 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.6 GO:0030575 nuclear body organization(GO:0030575)
0.0 1.6 GO:0042439 ethanolamine-containing compound metabolic process(GO:0042439)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.3 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 1.0 GO:0060487 lung epithelial cell differentiation(GO:0060487)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.0 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.4 GO:0006829 zinc II ion transport(GO:0006829)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0097447 dendritic tree(GO:0097447)
0.2 7.3 GO:0030673 axolemma(GO:0030673)
0.2 3.8 GO:0034706 sodium channel complex(GO:0034706)
0.1 1.2 GO:0045098 type III intermediate filament(GO:0045098)
0.1 3.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.9 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.8 GO:0005827 polar microtubule(GO:0005827)
0.1 1.6 GO:0044754 autolysosome(GO:0044754)
0.1 0.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.8 GO:0042627 chylomicron(GO:0042627)
0.1 0.6 GO:0042382 paraspeckles(GO:0042382)
0.1 4.8 GO:0005776 autophagosome(GO:0005776)
0.1 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.8 GO:0031011 Ino80 complex(GO:0031011)
0.1 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.7 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 10.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.5 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 3.7 GO:0072562 blood microparticle(GO:0072562)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.9 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 2.4 GO:0001650 fibrillar center(GO:0001650)
0.0 1.4 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.6 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.8 3.8 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.7 3.6 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.7 3.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.6 2.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.5 2.5 GO:0032810 sterol response element binding(GO:0032810)
0.5 3.6 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.3 1.0 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.3 2.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.3 3.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.3 1.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704) IkappaB kinase activity(GO:0008384)
0.2 4.0 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.2 1.8 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 0.7 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 1.6 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.2 5.7 GO:0070330 aromatase activity(GO:0070330)
0.2 0.7 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 1.7 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.2 1.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 3.1 GO:0019825 oxygen binding(GO:0019825)
0.2 1.8 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 2.9 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.5 GO:0019809 spermidine binding(GO:0019809)
0.1 0.8 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.9 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 4.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.7 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 0.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 1.0 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.1 0.6 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.3 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.7 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 1.2 GO:0019215 intermediate filament binding(GO:0019215)
0.1 3.2 GO:0005109 frizzled binding(GO:0005109)
0.1 0.9 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 1.5 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 1.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 1.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 4.2 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 1.0 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.8 GO:0016859 cis-trans isomerase activity(GO:0016859)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 2.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.0 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 1.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 13.5 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 3.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 3.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.4 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.7 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.2 8.5 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.2 3.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 7.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.3 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.1 3.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 0.8 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 2.5 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.1 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.8 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.7 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis