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GSE58827: Dynamics of the Mouse Liver

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Results for Nr2c1

Z-value: 0.69

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Transcription factors associated with Nr2c1

Gene Symbol Gene ID Gene Info
Nr2c1
ENSMUSG00000005897.8 nuclear receptor subfamily 2, group C, member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr2c1mm10_v2_chr10_+_94147982_941480230.038.8e-01Click!

Activity profile of Nr2c1 motif

Sorted Z-values of Nr2c1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_123894736 5.23 ENSMUST00000034453.4
Acta1
actin, alpha 1, skeletal muscle
chr15_+_80091320 4.63 ENSMUST00000009728.6
ENSMUST00000009727.5
Syngr1
synaptogyrin 1
chr9_+_65101453 4.23 ENSMUST00000077696.6
ENSMUST00000035499.4
ENSMUST00000166273.1
Igdcc4
immunoglobulin superfamily, DCC subclass, member 4
chr11_-_3504766 4.18 ENSMUST00000044507.5
Inpp5j
inositol polyphosphate 5-phosphatase J
chr8_-_122460666 3.74 ENSMUST00000006762.5
Snai3
snail homolog 3 (Drosophila)
chr17_-_8101228 3.44 ENSMUST00000097422.4
Gm1604A
predicted gene 1604A
chr7_+_110768169 3.37 ENSMUST00000170374.1
Ampd3
adenosine monophosphate deaminase 3
chr7_+_140093388 3.06 ENSMUST00000026540.8
Prap1
proline-rich acidic protein 1
chr15_-_89425856 2.66 ENSMUST00000109313.2
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr5_-_137741601 2.29 ENSMUST00000119498.1
ENSMUST00000061789.7
Nyap1
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr11_+_115877497 2.26 ENSMUST00000144032.1
Myo15b
myosin XVB
chr1_-_58973421 2.12 ENSMUST00000173590.1
ENSMUST00000027186.5
Trak2
trafficking protein, kinesin binding 2
chr2_+_29869484 1.88 ENSMUST00000047521.6
ENSMUST00000134152.1
Cercam
cerebral endothelial cell adhesion molecule
chr11_-_100207507 1.80 ENSMUST00000007272.7
Krt14
keratin 14
chr4_-_41048124 1.59 ENSMUST00000030136.6
Aqp7
aquaporin 7
chr15_-_89425795 1.51 ENSMUST00000168376.1
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr2_+_164805082 1.48 ENSMUST00000052107.4
Zswim3
zinc finger SWIM-type containing 3
chr5_-_137072254 1.45 ENSMUST00000077523.3
ENSMUST00000041388.4
Serpine1
serine (or cysteine) peptidase inhibitor, clade E, member 1
chr13_+_113342548 1.39 ENSMUST00000078163.7
BC067074
cDNA sequence BC067074
chr1_+_12718496 1.35 ENSMUST00000088585.3
Sulf1
sulfatase 1
chr6_-_83054415 1.28 ENSMUST00000113962.1
ENSMUST00000089645.6
ENSMUST00000113963.1
Htra2
HtrA serine peptidase 2
chr4_+_156215920 1.26 ENSMUST00000105572.1
2310042D19Rik
RIKEN cDNA 2310042D19 gene
chr7_+_30493622 1.23 ENSMUST00000058280.6
ENSMUST00000133318.1
ENSMUST00000142575.1
ENSMUST00000131040.1
Prodh2
proline dehydrogenase (oxidase) 2
chr4_-_83021102 1.20 ENSMUST00000071708.5
Frem1
Fras1 related extracellular matrix protein 1
chr14_-_70176787 1.17 ENSMUST00000153735.1
Pdlim2
PDZ and LIM domain 2
chr12_+_4082574 1.16 ENSMUST00000020986.7
Dnajc27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr2_-_30830333 1.16 ENSMUST00000041726.3
Asb6
ankyrin repeat and SOCS box-containing 6
chr7_-_45921418 1.13 ENSMUST00000038876.5
Emp3
epithelial membrane protein 3
chr12_-_83487708 1.10 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3
D4, zinc and double PHD fingers, family 3
chr13_+_44729794 1.08 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr2_-_62573813 1.08 ENSMUST00000174234.1
ENSMUST00000000402.9
ENSMUST00000174448.1
Fap
fibroblast activation protein
chr9_-_60687459 1.07 ENSMUST00000114032.1
ENSMUST00000166168.1
ENSMUST00000132366.1
Lrrc49
leucine rich repeat containing 49
chr2_-_54085542 1.04 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr4_-_129440800 1.04 ENSMUST00000053042.5
ENSMUST00000106046.1
Zbtb8b
zinc finger and BTB domain containing 8b
chr7_+_80186835 1.01 ENSMUST00000107383.1
ENSMUST00000032754.7
Sema4b
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr5_+_105519388 1.00 ENSMUST00000067924.6
ENSMUST00000150981.1
Lrrc8c
leucine rich repeat containing 8 family, member C
chr7_-_45920830 0.92 ENSMUST00000164119.1
Emp3
epithelial membrane protein 3
chr8_-_111393810 0.92 ENSMUST00000038475.8
Fa2h
fatty acid 2-hydroxylase
chr11_+_98383811 0.92 ENSMUST00000008021.2
Tcap
titin-cap
chr19_+_10937154 0.91 ENSMUST00000037261.3
Gpr44
G protein-coupled receptor 44
chr15_-_102366314 0.91 ENSMUST00000078508.5
Sp7
Sp7 transcription factor 7
chr4_+_127172866 0.88 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr10_+_127705170 0.85 ENSMUST00000079590.5
Myo1a
myosin IA
chr3_+_129213920 0.83 ENSMUST00000042587.10
Pitx2
paired-like homeodomain transcription factor 2
chr10_-_93589621 0.83 ENSMUST00000020203.6
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr5_+_117120120 0.83 ENSMUST00000111978.1
Taok3
TAO kinase 3
chrX_+_100729917 0.82 ENSMUST00000019503.7
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr1_-_74544275 0.81 ENSMUST00000044260.4
Usp37
ubiquitin specific peptidase 37
chr7_-_28598140 0.81 ENSMUST00000040531.8
ENSMUST00000108283.1
Samd4b
Pak4
sterile alpha motif domain containing 4B
p21 protein (Cdc42/Rac)-activated kinase 4
chr7_+_108934405 0.79 ENSMUST00000033342.6
Eif3f
eukaryotic translation initiation factor 3, subunit F
chr1_+_74506044 0.78 ENSMUST00000087215.5
Rqcd1
rcd1 (required for cell differentiation) homolog 1 (S. pombe)
chr2_+_22895482 0.78 ENSMUST00000053729.7
Pdss1
prenyl (solanesyl) diphosphate synthase, subunit 1
chrX_+_10485121 0.78 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7
tetraspanin 7
chr2_+_22895583 0.76 ENSMUST00000152170.1
Pdss1
prenyl (solanesyl) diphosphate synthase, subunit 1
chr9_-_65391652 0.76 ENSMUST00000068307.3
Kbtbd13
kelch repeat and BTB (POZ) domain containing 13
chr11_-_76577701 0.76 ENSMUST00000176179.1
Abr
active BCR-related gene
chr19_+_45998131 0.76 ENSMUST00000181820.1
4930505N22Rik
RIKEN cDNA 4930505N22 gene
chr11_+_4986824 0.75 ENSMUST00000009234.9
ENSMUST00000109897.1
Ap1b1
adaptor protein complex AP-1, beta 1 subunit
chr2_-_62573905 0.73 ENSMUST00000102732.3
Fap
fibroblast activation protein
chr7_-_19950729 0.72 ENSMUST00000043440.6
Igsf23
immunoglobulin superfamily, member 23
chr17_-_51810866 0.68 ENSMUST00000176669.1
Satb1
special AT-rich sequence binding protein 1
chr6_+_125145235 0.68 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
Iffo1
intermediate filament family orphan 1
chr11_+_3488275 0.67 ENSMUST00000064265.6
Pla2g3
phospholipase A2, group III
chr6_-_128275577 0.65 ENSMUST00000130454.1
Tead4
TEA domain family member 4
chr4_+_129461581 0.64 ENSMUST00000048162.8
ENSMUST00000138013.1
Bsdc1
BSD domain containing 1
chr2_+_106695594 0.64 ENSMUST00000016530.7
Mpped2
metallophosphoesterase domain containing 2
chr3_+_68572245 0.61 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr9_+_118506226 0.60 ENSMUST00000084820.4
Golga4
golgi autoantigen, golgin subfamily a, 4
chr4_-_117251879 0.59 ENSMUST00000165128.1
ENSMUST00000077500.4
Gm1661
predicted gene 1661
chr2_+_130406478 0.58 ENSMUST00000055421.4
Tmem239
transmembrane 239
chr10_-_119240006 0.56 ENSMUST00000020315.6
Cand1
cullin associated and neddylation disassociated 1
chrX_-_12160355 0.55 ENSMUST00000043441.6
Bcor
BCL6 interacting corepressor
chrX_-_102189371 0.54 ENSMUST00000033683.7
Rps4x
ribosomal protein S4, X-linked
chr4_+_131873608 0.53 ENSMUST00000053819.3
Srsf4
serine/arginine-rich splicing factor 4
chr17_+_35194502 0.51 ENSMUST00000173600.1
Ltb
lymphotoxin B
chr12_+_83987854 0.50 ENSMUST00000021649.7
Acot2
acyl-CoA thioesterase 2
chr19_-_45998479 0.48 ENSMUST00000045396.7
9130011E15Rik
RIKEN cDNA 9130011E15 gene
chrX_-_59567348 0.47 ENSMUST00000124402.1
Fgf13
fibroblast growth factor 13
chr5_+_135187251 0.47 ENSMUST00000002825.5
Baz1b
bromodomain adjacent to zinc finger domain, 1B
chr1_-_167285110 0.47 ENSMUST00000027839.8
Uck2
uridine-cytidine kinase 2
chr1_-_156939387 0.46 ENSMUST00000171292.1
Ralgps2
Ral GEF with PH domain and SH3 binding motif 2
chr9_-_14614949 0.44 ENSMUST00000013220.6
ENSMUST00000160770.1
Amotl1
angiomotin-like 1
chr3_+_90654253 0.42 ENSMUST00000079286.2
S100a7a
S100 calcium binding protein A7A
chr17_-_12992227 0.41 ENSMUST00000007007.7
Wtap
Wilms' tumour 1-associating protein
chr9_-_21037775 0.36 ENSMUST00000180870.1
Gm26592
predicted gene, 26592
chr3_+_58525821 0.35 ENSMUST00000029387.8
Eif2a
eukaryotic translation initiation factor 2A
chr5_+_137630116 0.35 ENSMUST00000175968.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr10_+_13008442 0.35 ENSMUST00000105139.3
Sf3b5
splicing factor 3b, subunit 5
chr3_+_58526303 0.35 ENSMUST00000138848.1
Eif2a
eukaryotic translation initiation factor 2A
chr15_-_79141197 0.35 ENSMUST00000169604.1
1700088E04Rik
RIKEN cDNA 1700088E04 gene
chr2_+_158794807 0.31 ENSMUST00000029186.7
ENSMUST00000109478.2
ENSMUST00000156893.1
Dhx35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr3_+_96830069 0.31 ENSMUST00000058865.7
Pdzk1
PDZ domain containing 1
chr10_+_93589413 0.30 ENSMUST00000181835.1
4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr14_+_20674311 0.29 ENSMUST00000048657.8
Sec24c
Sec24 related gene family, member C (S. cerevisiae)
chr3_+_129214269 0.29 ENSMUST00000174623.1
Pitx2
paired-like homeodomain transcription factor 2
chr11_-_64079444 0.26 ENSMUST00000049091.8
Cox10
cytochrome c oxidase assembly protein 10
chr14_+_57798182 0.25 ENSMUST00000111269.1
Sap18
Sin3-associated polypeptide 18
chr14_+_75136326 0.24 ENSMUST00000145303.1
Lcp1
lymphocyte cytosolic protein 1
chr9_-_107606656 0.24 ENSMUST00000073448.5
Sema3b
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr17_-_12992188 0.23 ENSMUST00000159986.1
Wtap
Wilms' tumour 1-associating protein
chr14_+_75136475 0.23 ENSMUST00000122840.1
Lcp1
lymphocyte cytosolic protein 1
chr11_-_107337556 0.22 ENSMUST00000040380.6
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr11_-_115808068 0.20 ENSMUST00000132780.1
Caskin2
CASK-interacting protein 2
chr11_+_83850863 0.19 ENSMUST00000108114.2
Hnf1b
HNF1 homeobox B
chr17_-_12992487 0.19 ENSMUST00000159551.1
ENSMUST00000160781.1
Wtap
Wilms' tumour 1-associating protein
chr10_+_4432467 0.19 ENSMUST00000095893.4
ENSMUST00000118544.1
ENSMUST00000117489.1
1700052N19Rik
RIKEN cDNA 1700052N19 gene
chr13_-_93192270 0.18 ENSMUST00000048702.5
Papd4
PAP associated domain containing 4
chr12_+_61523889 0.17 ENSMUST00000119481.1
ENSMUST00000055815.7
Lrfn5
leucine rich repeat and fibronectin type III domain containing 5
chr5_-_5265224 0.17 ENSMUST00000115450.1
Cdk14
cyclin-dependent kinase 14
chr11_+_83850832 0.17 ENSMUST00000021016.3
Hnf1b
HNF1 homeobox B
chr2_+_153345809 0.15 ENSMUST00000109790.1
Asxl1
additional sex combs like 1
chr14_+_57798620 0.15 ENSMUST00000111268.1
Sap18
Sin3-associated polypeptide 18
chr1_-_74284636 0.15 ENSMUST00000178235.1
ENSMUST00000006462.7
Aamp
angio-associated migratory protein
chr16_-_4523056 0.15 ENSMUST00000090500.3
ENSMUST00000023161.7
Srl
sarcalumenin
chr5_-_110779937 0.14 ENSMUST00000112426.1
Pus1
pseudouridine synthase 1
chr15_-_79505241 0.13 ENSMUST00000057801.6
Kcnj4
potassium inwardly-rectifying channel, subfamily J, member 4
chr10_-_67548944 0.13 ENSMUST00000075686.4
Ado
2-aminoethanethiol (cysteamine) dioxygenase
chr4_-_121109199 0.13 ENSMUST00000106268.3
Tmco2
transmembrane and coiled-coil domains 2
chr2_-_26237368 0.12 ENSMUST00000036187.8
Qsox2
quiescin Q6 sulfhydryl oxidase 2
chr9_-_106158109 0.12 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
Glyctk
glycerate kinase
chr5_-_110780569 0.12 ENSMUST00000149208.1
ENSMUST00000031483.8
ENSMUST00000086643.5
ENSMUST00000170468.1
ENSMUST00000031481.6
Pus1
pseudouridine synthase 1
chr17_+_75465538 0.10 ENSMUST00000095204.4
Rasgrp3
RAS, guanyl releasing protein 3
chr17_+_34850373 0.10 ENSMUST00000097343.4
ENSMUST00000173357.1
ENSMUST00000173065.1
ENSMUST00000165953.2
Nelfe
negative elongation factor complex member E, Rdbp
chr8_+_95825353 0.09 ENSMUST00000074053.4
Gm10094
predicted gene 10094
chr15_+_101224207 0.08 ENSMUST00000000543.4
Grasp
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr6_+_22875496 0.08 ENSMUST00000090568.3
Ptprz1
protein tyrosine phosphatase, receptor type Z, polypeptide 1
chr16_+_44139821 0.08 ENSMUST00000159514.1
ENSMUST00000161326.1
ENSMUST00000063520.8
ENSMUST00000063542.7
Naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr19_-_5688149 0.07 ENSMUST00000068169.5
Pcnxl3
pecanex-like 3 (Drosophila)
chr4_-_130174691 0.07 ENSMUST00000132545.2
ENSMUST00000175992.1
ENSMUST00000105999.2
Tinagl1
tubulointerstitial nephritis antigen-like 1
chr1_+_93215899 0.06 ENSMUST00000138595.1
E030010N08Rik
RIKEN cDNA E030010N08 gene
chr15_+_79141324 0.06 ENSMUST00000040077.6
Polr2f
polymerase (RNA) II (DNA directed) polypeptide F
chr2_+_110597298 0.06 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr14_+_57798156 0.06 ENSMUST00000128764.1
Sap18
Sin3-associated polypeptide 18
chr15_+_86214431 0.05 ENSMUST00000063414.8
Tbc1d22a
TBC1 domain family, member 22a
chr9_+_77046680 0.05 ENSMUST00000184488.1
RP23-282G22.2
RP23-282G22.2
chr6_+_22288221 0.04 ENSMUST00000128245.1
ENSMUST00000031681.3
ENSMUST00000148639.1
Wnt16
wingless-related MMTV integration site 16
chr7_+_45897429 0.04 ENSMUST00000140243.1
Tmem143
transmembrane protein 143
chr6_+_124663027 0.04 ENSMUST00000004381.7
Lpcat3
lysophosphatidylcholine acyltransferase 3
chr1_-_156718989 0.04 ENSMUST00000122424.1
Fam20b
family with sequence similarity 20, member B
chr7_+_82648595 0.03 ENSMUST00000141726.1
ENSMUST00000179489.1
ENSMUST00000039881.3
Eftud1
elongation factor Tu GTP binding domain containing 1
chr1_+_133309778 0.03 ENSMUST00000094557.4
ENSMUST00000183457.1
ENSMUST00000183738.1
ENSMUST00000185157.1
ENSMUST00000184603.1
Golt1a
Kiss1
GOLT1A
golgi transport 1 homolog A (S. cerevisiae)
KiSS-1 metastasis-suppressor
KISS1 isoform e
chr1_+_180726019 0.00 ENSMUST00000027780.4
Acbd3
acyl-Coenzyme A binding domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2c1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0010710 regulation of collagen catabolic process(GO:0010710) negative regulation of extracellular matrix disassembly(GO:0010716)
0.6 6.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.5 1.4 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.4 1.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.4 1.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.4 3.4 GO:0032264 IMP salvage(GO:0032264)
0.3 1.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 1.6 GO:0015793 glycerol transport(GO:0015793) renal water absorption(GO:0070295)
0.3 1.8 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.2 1.1 GO:0060578 subthalamic nucleus development(GO:0021763) superior vena cava morphogenesis(GO:0060578)
0.2 2.1 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.2 4.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.2 1.3 GO:1904923 negative regulation of macromitophagy(GO:1901525) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.2 3.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 0.5 GO:0009173 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.2 0.8 GO:0060313 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.1 0.5 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.7 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 0.7 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.4 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 2.1 GO:0032060 bleb assembly(GO:0032060)
0.1 0.9 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.5 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.4 GO:0061295 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.1 1.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 0.8 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.8 GO:0090527 actin filament reorganization(GO:0090527)
0.1 1.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.8 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.7 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.5 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.8 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 0.5 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.3 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.5 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0 1.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.3 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.9 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.9 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.6 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.3 GO:0015879 carnitine transport(GO:0015879)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.8 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 2.2 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.1 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.0 0.6 GO:0001553 luteinization(GO:0001553)
0.0 1.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.4 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.0 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.5 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.6 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0042583 chromaffin granule(GO:0042583)
0.2 1.8 GO:0071438 invadopodium membrane(GO:0071438)
0.2 0.8 GO:0036396 MIS complex(GO:0036396)
0.2 0.8 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.1 5.2 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.8 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.8 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0061574 ASAP complex(GO:0061574)
0.0 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.1 GO:0071565 nBAF complex(GO:0071565)
0.0 4.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 4.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 1.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 4.7 GO:0005903 brush border(GO:0005903)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 3.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 1.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 5.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.8 4.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.4 1.5 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.4 3.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.4 1.8 GO:1990254 keratin filament binding(GO:1990254)
0.3 1.6 GO:0015254 glycerol channel activity(GO:0015254)
0.3 1.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.9 GO:0051373 FATZ binding(GO:0051373)
0.2 1.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 2.1 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.8 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 1.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.9 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 1.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.3 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.3 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 1.2 GO:0071949 FAD binding(GO:0071949)
0.0 0.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 1.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 3.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.5 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 1.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 2.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 3.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 4.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 0.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing