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GSE58827: Dynamics of the Mouse Liver

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Results for Onecut2_Onecut3

Z-value: 0.80

Motif logo

Transcription factors associated with Onecut2_Onecut3

Gene Symbol Gene ID Gene Info
ENSMUSG00000045991.12 one cut domain, family member 2
ENSMUSG00000045518.8 one cut domain, family member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Onecut2mm10_v2_chr18_+_64340225_643403640.202.4e-01Click!
Onecut3mm10_v2_chr10_+_80494835_80494873-0.192.7e-01Click!

Activity profile of Onecut2_Onecut3 motif

Sorted Z-values of Onecut2_Onecut3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_62054112 3.76 ENSMUST00000074018.3
major urinary protein 20
chr4_-_61674094 3.73 ENSMUST00000098040.3
major urinary protein 18
chr4_-_61303802 2.98 ENSMUST00000125461.1
major urinary protein 14
chr4_-_61303998 2.53 ENSMUST00000071005.8
ENSMUST00000075206.5
major urinary protein 14
chr9_-_86695897 2.04 ENSMUST00000034989.8
malic enzyme 1, NADP(+)-dependent, cytosolic
chr7_-_34655500 1.81 ENSMUST00000032709.1
potassium channel tetramerisation domain containing 15
chr4_+_147553277 1.76 ENSMUST00000139784.1
ENSMUST00000143885.1
ENSMUST00000081742.6
predicted gene 13154
chr4_-_147642496 1.70 ENSMUST00000133006.1
ENSMUST00000037565.7
ENSMUST00000105720.1
RIKEN cDNA 2610305D13 gene
chr4_+_147361303 1.57 ENSMUST00000133078.1
ENSMUST00000154154.1
predicted gene 13145
chr17_-_34804546 1.38 ENSMUST00000025223.8
cytochrome P450, family 21, subfamily a, polypeptide 1
chr15_-_89477400 1.26 ENSMUST00000165199.1
arylsulfatase A
chr4_+_146097312 1.16 ENSMUST00000105730.1
ENSMUST00000091878.5
predicted gene 13051
chr15_+_62039216 1.12 ENSMUST00000183297.1
plasmacytoma variant translocation 1
chr3_-_98588807 1.00 ENSMUST00000178221.1
predicted gene 10681
chr7_+_131032061 0.99 ENSMUST00000084509.3
deleted in malignant brain tumors 1
chr5_-_87254804 0.91 ENSMUST00000075858.3
UDP glucuronosyltransferase 2 family, polypeptide B37
chr5_+_109940426 0.88 ENSMUST00000170826.1
predicted gene 15446
chr10_-_63203930 0.77 ENSMUST00000095580.2
myopalladin
chr4_+_109343029 0.77 ENSMUST00000030281.5
epidermal growth factor receptor pathway substrate 15
chr18_-_9282754 0.69 ENSMUST00000041007.3
gap junction protein, delta 4
chr2_+_55411790 0.67 ENSMUST00000155997.1
ENSMUST00000128307.1
predicted gene 14033
chr17_-_33033367 0.66 ENSMUST00000087654.4
zinc finger protein 763
chr17_-_28560704 0.62 ENSMUST00000114785.1
ENSMUST00000025062.3
colipase, pancreatic
chr4_+_147492417 0.61 ENSMUST00000105721.2
predicted gene 13152
chr7_+_123462274 0.61 ENSMUST00000033023.3
aquaporin 8
chr14_+_17981633 0.59 ENSMUST00000022304.8
thyroid hormone receptor beta
chr6_+_78405148 0.58 ENSMUST00000023906.2
regenerating islet-derived 2
chr2_-_175131864 0.56 ENSMUST00000108929.2
predicted gene 14399
chr6_+_29853746 0.56 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
S-adenosylhomocysteine hydrolase-like 2
chr18_+_3471630 0.55 ENSMUST00000179907.1
RIKEN cDNA G430049J08 gene
chr11_+_96282529 0.54 ENSMUST00000125410.1
homeobox B8
chr19_-_9559204 0.54 ENSMUST00000090527.3
syntaxin-binding protein 3B
chr12_+_88083697 0.53 ENSMUST00000177720.1
predicted pseudogene 16368
chr6_-_78468863 0.52 ENSMUST00000032089.2
regenerating islet-derived 3 gamma
chr4_+_147021850 0.51 ENSMUST00000075775.5
reduced expression 2
chr6_-_129876659 0.50 ENSMUST00000014687.4
ENSMUST00000122219.1
killer cell lectin-like receptor, subfamily A, member 17
chr13_-_95478655 0.49 ENSMUST00000022186.3
S100 calcium binding protein, zeta
chr2_-_169962987 0.49 ENSMUST00000087964.2
cDNA sequence AY702102
chr5_+_8422908 0.48 ENSMUST00000170496.1
solute carrier family 25, member 40
chr1_-_5070281 0.48 ENSMUST00000147158.1
ENSMUST00000118000.1
regulator of G-protein signaling 20
chrX_+_42151002 0.47 ENSMUST00000123245.1
stromal antigen 2
chr8_+_4625840 0.47 ENSMUST00000073201.5
zinc finger protein 958
chr2_-_17390953 0.47 ENSMUST00000177966.1
nebulette
chr15_-_103215285 0.46 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
chromobox 5
chr4_+_146156824 0.46 ENSMUST00000168483.2
zinc finger protein 600
chr14_-_56211407 0.46 ENSMUST00000022757.3
granzyme F
chr1_+_138273722 0.46 ENSMUST00000027643.4
ATPase, H+ transporting, lysosomal V1 subunit G3
chr6_+_141524379 0.45 ENSMUST00000032362.9
solute carrier organic anion transporter family, member 1c1
chr3_+_138143846 0.44 ENSMUST00000159481.1
tRNA methyltransferase 10A
chr1_-_170215380 0.43 ENSMUST00000027979.7
ENSMUST00000123399.1
U2AF homology motif (UHM) kinase 1
chr11_+_96282648 0.42 ENSMUST00000168043.1
homeobox B8
chr12_+_59131473 0.41 ENSMUST00000177162.1
CTAGE family, member 5
chr12_+_59131286 0.41 ENSMUST00000176464.1
ENSMUST00000170992.2
ENSMUST00000176322.1
CTAGE family, member 5
chr3_+_153844209 0.41 ENSMUST00000044089.3
ankyrin repeat and SOCS box-containing 17
chr3_+_53845086 0.41 ENSMUST00000108014.1
predicted gene 10985
chr9_-_109162021 0.40 ENSMUST00000120329.1
ENSMUST00000054925.6
F-box and WD-40 domain protein 21
chr1_-_131200089 0.40 ENSMUST00000068564.8
Ras association (RalGDS/AF-6) domain family member 5
chr1_-_64121389 0.39 ENSMUST00000055001.3
Kruppel-like factor 7 (ubiquitous)
chr6_+_139843648 0.39 ENSMUST00000087657.6
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
chrX_-_113185485 0.37 ENSMUST00000026607.8
ENSMUST00000113388.2
choroidermia
chr18_-_24530203 0.37 ENSMUST00000046206.3
regulation of nuclear pre-mRNA domain containing 1A
chr17_+_17316078 0.37 ENSMUST00000105311.3
predicted gene 6712
chr1_-_180256294 0.37 ENSMUST00000111108.3
presenilin 2
chr15_+_102459028 0.37 ENSMUST00000164938.1
ENSMUST00000023810.5
proline rich 13
chr11_-_17953861 0.36 ENSMUST00000076661.6
Ewing's tumor-associated antigen 1
chr16_+_25286810 0.36 ENSMUST00000056087.3
transformation related protein 63 regulated
chr4_+_140701466 0.35 ENSMUST00000038893.5
ENSMUST00000138808.1
regulator of chromosome condensation 2
chrX_-_75161620 0.34 ENSMUST00000165080.1
small integral membrane protein 9
chr5_-_108795352 0.34 ENSMUST00000004943.1
transmembrane emp24 protein transport domain containing
chr17_+_24720063 0.34 ENSMUST00000170715.1
ENSMUST00000054289.6
ENSMUST00000146867.1
ribosomal protein S2
chr5_-_17849783 0.33 ENSMUST00000170051.1
ENSMUST00000165232.1
CD36 antigen
chr6_+_29694204 0.33 ENSMUST00000046750.7
ENSMUST00000115250.3
tetraspanin 33
chr15_-_79328154 0.33 ENSMUST00000166977.2
phospholipase A2, group VI
chr9_+_53771499 0.33 ENSMUST00000048670.8
solute carrier family 35, member F2
chr11_+_74830920 0.33 ENSMUST00000000291.2
max binding protein
chr2_+_104069819 0.32 ENSMUST00000111131.2
ENSMUST00000111132.1
ENSMUST00000129749.1
CD59b antigen
chr8_+_47824459 0.32 ENSMUST00000038693.6
claudin 22
chr8_+_3515378 0.32 ENSMUST00000004681.7
ENSMUST00000111070.2
patatin-like phospholipase domain containing 6
chr11_-_24075054 0.31 ENSMUST00000068360.1
RIKEN cDNA A830031A19 gene
chr15_+_102459193 0.31 ENSMUST00000164957.1
ENSMUST00000171245.1
proline rich 13
chr15_-_79328201 0.30 ENSMUST00000173163.1
ENSMUST00000047816.8
ENSMUST00000172403.2
ENSMUST00000173632.1
phospholipase A2, group VI
chr5_-_147894804 0.29 ENSMUST00000118527.1
ENSMUST00000031655.3
ENSMUST00000138244.1
solute carrier family 46, member 3
chr5_-_138207302 0.29 ENSMUST00000160126.1
predicted gene 454
chr4_+_145510759 0.29 ENSMUST00000105742.1
ENSMUST00000136309.1
predicted gene 13225
chr4_+_43383449 0.28 ENSMUST00000135216.1
ENSMUST00000152322.1
RUN and SH3 domain containing 2
chr17_+_21657582 0.28 ENSMUST00000039726.7
RIKEN cDNA 3110052M02 gene
chr15_-_42676967 0.28 ENSMUST00000022921.5
angiopoietin 1
chr10_-_45470201 0.27 ENSMUST00000079390.6
lin-28 homolog B (C. elegans)
chr18_-_10030017 0.27 ENSMUST00000116669.1
ENSMUST00000092096.6
ubiquitin specific peptidase 14
chr4_+_145670685 0.27 ENSMUST00000105738.2
predicted gene 13242
chr16_-_22657182 0.26 ENSMUST00000023578.7
diacylglycerol kinase, gamma
chrX_-_111536325 0.26 ENSMUST00000156639.1
ribosomal protein S6 kinase polypeptide 6
chr4_-_99654983 0.25 ENSMUST00000136525.1
predicted gene 12688
chr7_-_73541738 0.25 ENSMUST00000169922.2
chromodomain helicase DNA binding protein 2
chrY_+_51126655 0.25 ENSMUST00000180133.1
predicted gene, 21117
chr5_-_129623655 0.25 ENSMUST00000076842.5
predicted gene 6139
chr16_+_48310427 0.25 ENSMUST00000097175.4
developmental pluripotency associated 2
chr6_+_127149389 0.25 ENSMUST00000180811.1
RIKEN cDNA 9330179D12 gene
chr12_+_59080988 0.25 ENSMUST00000085368.3
predicted pseudogene 5786
chr11_+_115334731 0.25 ENSMUST00000106543.1
ENSMUST00000019006.4
otopetrin 3
chr3_+_102010138 0.24 ENSMUST00000066187.4
nescient helix loop helix 2
chr7_-_140507318 0.24 ENSMUST00000064392.6
olfactory receptor 536
chr9_-_20728219 0.24 ENSMUST00000034692.7
olfactomedin 2
chr8_+_93810832 0.24 ENSMUST00000034198.8
ENSMUST00000125716.1
guanine nucleotide binding protein, alpha O
chr15_+_55112317 0.24 ENSMUST00000096433.3
DEP domain containing MTOR-interacting protein
chr10_-_53647080 0.23 ENSMUST00000169866.1
family with sequence similarity 184, member A
chr4_+_146502027 0.22 ENSMUST00000105735.2
predicted gene 13247
chr16_-_22657165 0.22 ENSMUST00000089925.3
diacylglycerol kinase, gamma
chr13_-_55415166 0.21 ENSMUST00000054146.3
profilin 3
chr7_+_35802593 0.21 ENSMUST00000052454.2
RIKEN cDNA E130304I02 gene
chrY_-_35130404 0.21 ENSMUST00000180170.1
predicted gene, 20855
chr15_+_27025386 0.21 ENSMUST00000169678.2
predicted gene 6576
chr14_+_61138445 0.20 ENSMUST00000089394.3
ENSMUST00000119509.1
sacsin
chr2_-_181581996 0.20 ENSMUST00000057816.8
uridine-cytidine kinase 1-like 1
chr13_-_22041352 0.20 ENSMUST00000102977.2
histone cluster 1, H4i
chr4_+_146971976 0.20 ENSMUST00000146688.2
predicted gene 13150
chr16_-_10543028 0.20 ENSMUST00000184863.1
ENSMUST00000038281.5
dexamethasone-induced transcript
chr16_-_36131156 0.20 ENSMUST00000161638.1
ENSMUST00000096090.2
cystatin A
chr14_-_122451109 0.20 ENSMUST00000081580.2
predicted gene 5089
chr7_+_44207307 0.19 ENSMUST00000077354.4
kallikrein 1-related pepidase b4
chr5_+_32458974 0.19 ENSMUST00000015100.8
protein phosphatase 1, catalytic subunit, beta isoform
chr13_-_106936907 0.19 ENSMUST00000080856.7
importin 11
chr18_-_61259987 0.19 ENSMUST00000170335.2
ribosomal protein S2, pseudogene 10
chr18_+_57468478 0.19 ENSMUST00000091892.2
cortexin 3
chr6_-_38109548 0.19 ENSMUST00000114908.1
ATPase, H+ transporting, lysosomal V0 subunit A4
chr1_+_172698046 0.19 ENSMUST00000038495.3
C-reactive protein, pentraxin-related
chr6_-_51469836 0.19 ENSMUST00000090002.7
heterogeneous nuclear ribonucleoprotein A2/B1
chr11_+_108587077 0.18 ENSMUST00000146912.2
centrosomal protein 112
chr8_-_106573461 0.18 ENSMUST00000073722.5
predicted pseudogene 10073
chr11_-_99556846 0.18 ENSMUST00000092699.2
keratin associated protein 3-2
chr6_+_127233756 0.18 ENSMUST00000071458.3
predicted gene 4968
chr17_+_12119274 0.18 ENSMUST00000024594.2
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr5_+_29735688 0.17 ENSMUST00000008733.8
DnaJ (Hsp40) homolog, subfamily B, member 6
chr12_-_34291092 0.17 ENSMUST00000166546.2
predicted gene, 18025
chr15_+_55112420 0.17 ENSMUST00000100660.4
DEP domain containing MTOR-interacting protein
chr3_+_94837702 0.17 ENSMUST00000107266.1
ENSMUST00000042402.5
ENSMUST00000107269.1
pogo transposable element with ZNF domain
chr1_-_63114516 0.17 ENSMUST00000097718.2
INO80 complex subunit D
chr2_-_63184253 0.17 ENSMUST00000075052.3
ENSMUST00000112454.1
potassium voltage-gated channel, subfamily H (eag-related), member 7
chrY_+_80135210 0.16 ENSMUST00000179811.1
predicted gene, 21760
chr7_-_110844350 0.16 ENSMUST00000177462.1
ENSMUST00000176746.1
ENSMUST00000177236.1
ring finger protein 141
chr6_-_135118240 0.16 ENSMUST00000032327.7
ENSMUST00000111922.1
G protein-coupled receptor, family C, group 5, member D
chrX_+_102802963 0.16 ENSMUST00000118218.1
DMRT-like family C1c1
chr3_+_94837533 0.16 ENSMUST00000107270.2
pogo transposable element with ZNF domain
chr9_-_14782964 0.15 ENSMUST00000034406.3
ankyrin repeat domain 49
chr17_+_32468462 0.15 ENSMUST00000003413.6
cytochrome P450, family 4, subfamily f, polypeptide 39
chr2_-_25224653 0.15 ENSMUST00000043584.4
tubulin, beta 4B class IVB
chr14_-_68655804 0.15 ENSMUST00000111072.1
ENSMUST00000022642.5
a disintegrin and metallopeptidase domain 28
chr6_+_48929891 0.15 ENSMUST00000031837.7
RIKEN cDNA 1600015I10 gene
chr12_+_74288735 0.15 ENSMUST00000095617.1
RIKEN cDNA 1700086L19 gene
chr3_+_106034661 0.15 ENSMUST00000170669.2
predicted gene 4540
chr18_-_62756275 0.15 ENSMUST00000067450.1
ENSMUST00000048109.5
RIKEN cDNA 2700046A07 gene
chr5_-_130255525 0.14 ENSMUST00000026387.4
Shwachman-Bodian-Diamond syndrome homolog (human)
chr7_-_57386871 0.14 ENSMUST00000068394.6
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
chr14_-_120042429 0.14 ENSMUST00000058213.5
oxoglutarate (alpha-ketoglutarate) receptor 1
chr1_-_64121456 0.14 ENSMUST00000142009.1
ENSMUST00000114086.1
Kruppel-like factor 7 (ubiquitous)
chr3_-_30140407 0.14 ENSMUST00000108271.3
MDS1 and EVI1 complex locus
chr6_-_82939676 0.14 ENSMUST00000000641.9
ENSMUST00000113982.1
sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain
chr5_-_65335564 0.14 ENSMUST00000172780.1
replication factor C (activator 1) 1
chr3_+_136670076 0.14 ENSMUST00000070198.7
protein phosphatase 3, catalytic subunit, alpha isoform
chr11_-_70669283 0.14 ENSMUST00000129434.1
ENSMUST00000018431.6
sperm associated antigen 7
chr3_-_10183885 0.14 ENSMUST00000029034.7
peripheral myelin protein 2
chr13_+_90923122 0.13 ENSMUST00000051955.7
ribosomal protein S23
chr6_-_127769427 0.13 ENSMUST00000032500.8
protein arginine N-methyltransferase 8
chr5_+_122100951 0.13 ENSMUST00000014080.6
ENSMUST00000111750.1
ENSMUST00000139213.1
ENSMUST00000111751.1
ENSMUST00000155612.1
myosin, light polypeptide 2, regulatory, cardiac, slow
chr6_+_116208030 0.13 ENSMUST00000036759.8
family with sequence similarity 21
chr1_+_153749414 0.13 ENSMUST00000086209.3
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr6_+_134640940 0.13 ENSMUST00000062755.8
loss of heterozygosity, 12, chromosomal region 1 homolog (human)
chr17_+_21566988 0.12 ENSMUST00000088787.5
zinc finger protein 948
chr16_-_43664145 0.12 ENSMUST00000096065.4
T cell immunoreceptor with Ig and ITIM domains
chr18_+_35771574 0.12 ENSMUST00000167406.1
ubiquitin-conjugating enzyme E2D 2A
chr3_-_10351313 0.11 ENSMUST00000108377.1
ENSMUST00000037839.5
zinc finger, AN1-type domain 1
chr2_+_144594054 0.11 ENSMUST00000136628.1
predicted gene 561
chr12_-_84698769 0.11 ENSMUST00000095550.2
synapse differentiation inducing 1 like
chr9_-_64253617 0.11 ENSMUST00000005066.8
mitogen-activated protein kinase kinase 1
chr9_-_50739365 0.11 ENSMUST00000117093.1
ENSMUST00000121634.1
DIX domain containing 1
chr2_+_86297817 0.11 ENSMUST00000054746.2
olfactory receptor 1052
chr18_-_53744509 0.11 ENSMUST00000049811.6
centrosomal protein 120
chr5_+_122101146 0.11 ENSMUST00000147178.1
myosin, light polypeptide 2, regulatory, cardiac, slow
chr6_-_51469869 0.11 ENSMUST00000114459.1
ENSMUST00000069949.6
heterogeneous nuclear ribonucleoprotein A2/B1
chr11_+_29373618 0.11 ENSMUST00000040182.6
ENSMUST00000109477.1
coiled coil domain containing 88A
chr4_-_109156610 0.11 ENSMUST00000161363.1
oxysterol binding protein-like 9
chr10_+_112083345 0.10 ENSMUST00000148897.1
ENSMUST00000020434.3
GLI pathogenesis-related 1 like 2
chr4_+_43384332 0.10 ENSMUST00000136360.1
RUN and SH3 domain containing 2
chr1_+_49244616 0.10 ENSMUST00000056879.8
RIKEN cDNA C230029F24 gene
chr16_+_17619341 0.10 ENSMUST00000006053.6
ENSMUST00000171435.1
ENSMUST00000163476.1
ENSMUST00000168101.1
ENSMUST00000165363.1
ENSMUST00000169662.1
ENSMUST00000090159.4
ENSMUST00000172182.1
ENSMUST00000163592.1
sphingomyelin phosphodiesterase 4
chr18_+_62657285 0.10 ENSMUST00000162511.1
serine peptidase inhibitor, Kazal type 10
chrX_+_119927196 0.10 ENSMUST00000040961.2
ENSMUST00000113366.1
poly(A) binding protein, cytoplasmic 5
chr10_-_64090241 0.10 ENSMUST00000133588.1
leucine rich repeat transmembrane neuronal 3
chr8_-_109251698 0.10 ENSMUST00000079189.3
RIKEN cDNA 4922502B01 gene
chr12_-_31950535 0.10 ENSMUST00000172314.2
high mobility group box transcription factor 1
chr17_+_29660595 0.10 ENSMUST00000024816.6
cap methyltransferase 1
chr6_+_127072902 0.10 ENSMUST00000000186.6
fibroblast growth factor 23
chr11_-_98329641 0.10 ENSMUST00000041685.6
neurogenic differentiation 2
chr12_+_109545390 0.10 ENSMUST00000146701.1
maternally expressed 3
chrX_-_95658416 0.10 ENSMUST00000044382.6
zinc finger, C4H2 domain containing
chr9_-_69451035 0.10 ENSMUST00000071565.5
predicted gene 4978
chr17_-_71459300 0.09 ENSMUST00000183937.1
predicted gene 4707
chr3_+_107090874 0.09 ENSMUST00000060946.3
ENSMUST00000182132.1
RIKEN cDNA A930002I21 gene
chrX_-_95658379 0.09 ENSMUST00000119640.1
zinc finger, C4H2 domain containing
chr1_-_144177259 0.09 ENSMUST00000111941.1
ENSMUST00000052375.1
regulator of G-protein signaling 13

Network of associatons between targets according to the STRING database.

First level regulatory network of Onecut2_Onecut3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.8 GO:0008355 olfactory learning(GO:0008355)
0.3 2.0 GO:0006108 malate metabolic process(GO:0006108) regulation of NADP metabolic process(GO:1902031)
0.2 0.7 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.1 0.6 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.3 GO:0070543 response to linoleic acid(GO:0070543)
0.1 0.6 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.3 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.3 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.6 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 1.4 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705)
0.1 0.8 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 0.6 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.6 GO:0051715 cytolysis in other organism(GO:0051715)
0.1 1.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.3 GO:0001905 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.0 0.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.3 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 1.0 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 1.2 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.6 GO:0001967 suckling behavior(GO:0001967)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.0 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.6 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.4 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.9 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.3 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.1 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.4 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.3 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.0 GO:0070836 caveola assembly(GO:0070836)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.5 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.2 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0046691 intracellular canaliculus(GO:0046691)
0.1 1.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.7 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.8 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.6 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 0.5 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.6 GO:0000800 lateral element(GO:0000800)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0005186 pheromone activity(GO:0005186)
0.7 2.0 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 1.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.6 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.5 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.6 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.6 GO:0015250 water channel activity(GO:0015250)
0.0 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0051430 G-protein coupled serotonin receptor binding(GO:0031821) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.8 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 2.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis