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GSE58827: Dynamics of the Mouse Liver

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Results for Pitx2_Otx2

Z-value: 2.18

Motif logo

Transcription factors associated with Pitx2_Otx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000028023.10 paired-like homeodomain transcription factor 2
ENSMUSG00000021848.9 orthodenticle homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pitx2mm10_v2_chr3_+_129199919_1291999430.626.1e-05Click!
Otx2mm10_v2_chr14_-_48662740_486628720.241.5e-01Click!

Activity profile of Pitx2_Otx2 motif

Sorted Z-values of Pitx2_Otx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_36184082 30.10 ENSMUST00000114858.1
predicted gene 5483
chr16_-_36367623 27.57 ENSMUST00000096089.2
cDNA sequence BC100530
chr14_-_70630149 17.93 ENSMUST00000022694.9
dematin actin binding protein
chrX_-_7978027 16.81 ENSMUST00000125418.1
GATA binding protein 1
chr5_+_90490714 15.58 ENSMUST00000042755.3
alpha fetoprotein
chr2_-_126500631 15.04 ENSMUST00000129187.1
ATPase, class I, type 8B, member 4
chr16_+_36277145 14.88 ENSMUST00000042097.9
stefin A1
chrX_-_7967817 14.50 ENSMUST00000033502.7
GATA binding protein 1
chr10_+_79886302 14.14 ENSMUST00000046091.5
elastase, neutrophil expressed
chr6_-_88898664 13.92 ENSMUST00000058011.6
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr15_-_76669811 13.79 ENSMUST00000037824.4
forkhead box H1
chr16_-_36334330 11.61 ENSMUST00000114850.2
cDNA sequence BC1179090
chr11_-_83286722 11.44 ENSMUST00000163961.2
schlafen family member 14
chr17_-_35085609 11.00 ENSMUST00000038507.6
lymphocyte antigen 6 complex, locus G6F
chr9_-_70421533 10.88 ENSMUST00000034742.6
cyclin B2
chr6_-_115762346 10.80 ENSMUST00000166254.1
ENSMUST00000170625.1
transmembrane protein 40
chr16_+_32186192 10.40 ENSMUST00000099990.3
brain expressed gene 6
chr17_+_48232755 10.09 ENSMUST00000113251.3
ENSMUST00000048782.6
triggering receptor expressed on myeloid cells 1
chr19_-_45812291 10.05 ENSMUST00000086993.4
Kv channel-interacting protein 2
chr11_-_55185029 9.96 ENSMUST00000039305.5
solute carrier family 36 (proton/amino acid symporter), member 2
chr17_+_29114142 9.87 ENSMUST00000141797.1
ENSMUST00000132262.1
ENSMUST00000141239.1
ENSMUST00000138816.1
predicted gene 16194
chr15_-_78855517 9.81 ENSMUST00000044584.4
lectin, galactose-binding, soluble 2
chr7_+_16781341 9.63 ENSMUST00000108496.2
solute carrier family 1 (neutral amino acid transporter), member 5
chrX_+_164140447 9.37 ENSMUST00000073973.4
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr17_-_35188427 9.30 ENSMUST00000097336.4
leukocyte specific transcript 1
chr11_+_61956779 9.27 ENSMUST00000049836.7
sperm antigen with calponin homology and coiled-coil domains 1
chr11_+_117782281 9.27 ENSMUST00000050874.7
ENSMUST00000106334.2
transmembrane channel-like gene family 8
chr3_-_90695706 9.22 ENSMUST00000069960.5
ENSMUST00000117167.1
S100 calcium binding protein A9 (calgranulin B)
chr11_+_117782076 9.13 ENSMUST00000127080.1
transmembrane channel-like gene family 8
chr11_-_6520894 9.10 ENSMUST00000003459.3
myosin IG
chr11_-_97996171 8.99 ENSMUST00000042971.9
ADP-ribosylation factor-like 5C
chr7_-_75782080 8.93 ENSMUST00000181224.1
expressed sequence AU020206
chr10_-_62342674 8.86 ENSMUST00000143179.1
ENSMUST00000130422.1
hexokinase 1
chr7_-_47528862 8.83 ENSMUST00000172559.1
MAS-related GPR, member A2B
chr7_+_141131268 8.60 ENSMUST00000026568.8
phosphatidylserine synthase 2
chr17_-_25944932 8.52 ENSMUST00000085027.3
NHL repeat containing 4
chr4_-_117182623 8.37 ENSMUST00000065896.2
kinesin family member 2C
chr18_-_60501983 8.29 ENSMUST00000042710.6
small integral membrane protein 3
chr17_+_35861318 8.22 ENSMUST00000074259.8
ENSMUST00000174873.1
nurim (nuclear envelope membrane protein)
chr14_-_47411666 8.16 ENSMUST00000111778.3
discs, large (Drosophila) homolog-associated protein 5
chr16_+_36210403 8.10 ENSMUST00000089628.3
predicted gene 5416
chr13_-_22009730 8.05 ENSMUST00000006341.2
protease, serine, 16 (thymus)
chr13_+_54701457 7.97 ENSMUST00000037145.7
cadherin-related family member 2
chr9_+_110419750 7.86 ENSMUST00000035061.6
neutrophilic granule protein
chr14_+_32166104 7.82 ENSMUST00000164341.1
nuclear receptor coactivator 4
chr3_-_36571952 7.56 ENSMUST00000029270.3
cyclin A2
chr8_-_10928449 7.48 ENSMUST00000040608.3
RIKEN cDNA 3930402G23 gene
chr8_+_23139064 7.45 ENSMUST00000033947.8
ankyrin 1, erythroid
chr7_-_6696423 7.40 ENSMUST00000002336.8
zinc finger, imprinted 1
chr6_+_86628174 7.24 ENSMUST00000043400.6
aspartic peptidase, retroviral-like 1
chr8_+_84901928 7.24 ENSMUST00000067060.7
Kruppel-like factor 1 (erythroid)
chr7_+_35449035 7.18 ENSMUST00000118969.1
ENSMUST00000118383.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr11_+_95010277 7.14 ENSMUST00000124735.1
sterile alpha motif domain containing 14
chr8_+_23139030 7.08 ENSMUST00000121075.1
ankyrin 1, erythroid
chr11_-_117782182 7.05 ENSMUST00000152304.1
transmembrane channel-like gene family 6
chr14_-_47418407 6.75 ENSMUST00000043296.3
discs, large (Drosophila) homolog-associated protein 5
chr5_+_76656512 6.75 ENSMUST00000086909.4
predicted gene 10430
chr9_+_107992463 6.72 ENSMUST00000177173.1
cadherin-related family member 4
chr10_+_20347788 6.66 ENSMUST00000169712.1
mitochondrial fission regulator 2
chr17_+_35861343 6.66 ENSMUST00000172931.1
nurim (nuclear envelope membrane protein)
chr16_+_38362205 6.65 ENSMUST00000023494.6
popeye domain containing 2
chr8_-_85386310 6.63 ENSMUST00000137290.1
myosin light chain kinase 3
chr1_+_134111233 6.60 ENSMUST00000159963.1
ENSMUST00000160060.1
chitinase 1 (chitotriosidase)
chr3_-_105932664 6.58 ENSMUST00000098758.2
RIKEN cDNA I830077J02 gene
chr11_-_116581446 6.57 ENSMUST00000082152.4
ubiquitin-conjugating enzyme E2O
chr10_+_75948292 6.49 ENSMUST00000000926.2
pre-B lymphocyte gene 3
chr12_+_79208928 6.47 ENSMUST00000122227.1
retinol dehydrogenase 12
chr12_+_79208904 6.40 ENSMUST00000021548.5
retinol dehydrogenase 12
chr10_-_128401218 6.37 ENSMUST00000042666.5
solute carrier family 39 (metal ion transporter), member 5
chrX_+_8271642 6.37 ENSMUST00000115590.1
solute carrier family 38, member 5
chr7_-_45526146 6.33 ENSMUST00000167273.1
ENSMUST00000042105.8
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr12_+_109734969 6.31 ENSMUST00000182268.1
ENSMUST00000181543.2
ENSMUST00000183116.1
miRNA containing gene
chr7_-_143460989 6.30 ENSMUST00000167912.1
ENSMUST00000037287.6
cyclin-dependent kinase inhibitor 1C (P57)
chr16_+_32756336 6.30 ENSMUST00000135753.1
mucin 4
chr14_+_27000362 6.22 ENSMUST00000035433.8
homeobox gene expressed in ES cells
chr6_+_134929089 6.16 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5
chr17_+_6430112 6.05 ENSMUST00000179569.1
dynein light chain Tctex-type 1B
chr6_+_134929118 6.03 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5
chr16_+_38362234 6.01 ENSMUST00000114739.1
popeye domain containing 2
chr18_-_74207771 5.99 ENSMUST00000040188.8
ENSMUST00000177604.1
spindle and kinetochore associated complex subunit 1
chr9_-_123678873 5.94 ENSMUST00000040960.6
solute carrier family 6 (neurotransmitter transporter), member 20A
chr7_+_45554893 5.84 ENSMUST00000107752.3
hydroxysteroid (17-beta) dehydrogenase 14
chr7_+_35449154 5.84 ENSMUST00000032703.9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr18_+_64254359 5.74 ENSMUST00000025477.7
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr9_-_67832325 5.69 ENSMUST00000054500.5
C2 calcium-dependent domain containing 4A
chr9_+_21029373 5.61 ENSMUST00000001040.5
intercellular adhesion molecule 4, Landsteiner-Wiener blood group
chr7_-_30823766 5.54 ENSMUST00000053156.3
free fatty acid receptor 2
chr15_+_76879232 5.53 ENSMUST00000023179.5
zinc finger protein 7
chr6_-_136401830 5.52 ENSMUST00000058713.7
RIKEN cDNA E330021D16 gene
chr3_-_54915867 5.52 ENSMUST00000070342.3
serine rich and transmembrane domain containing 1
chr11_-_5152218 5.49 ENSMUST00000163299.1
ENSMUST00000062821.6
EMI domain containing 1
chr7_-_118116128 5.47 ENSMUST00000128482.1
ENSMUST00000131840.1
ribosomal protein S15A
chr7_+_28441026 5.46 ENSMUST00000135686.1
glia maturation factor, gamma
chr15_-_76639840 5.44 ENSMUST00000166974.1
ENSMUST00000168185.1
tonsoku-like, DNA repair protein
chr15_+_99006056 5.41 ENSMUST00000079818.3
predicted gene 8973
chr7_-_100514800 5.40 ENSMUST00000054923.7
DnaJ (Hsp40) related, subfamily B, member 13
chr3_+_105870898 5.38 ENSMUST00000010279.5
adenosine A3 receptor
chr4_-_149137536 5.37 ENSMUST00000176124.1
ENSMUST00000177408.1
ENSMUST00000105695.1
ENSMUST00000030813.3
apoptosis-inducing, TAF9-like domain 1
chr4_+_108579445 5.33 ENSMUST00000102744.3
origin recognition complex, subunit 1
chr9_-_123678782 5.33 ENSMUST00000170591.1
ENSMUST00000171647.1
solute carrier family 6 (neurotransmitter transporter), member 20A
chr13_+_45507438 5.29 ENSMUST00000000260.6
guanosine monophosphate reductase
chr17_-_33713372 5.23 ENSMUST00000173392.1
membrane-associated ring finger (C3HC4) 2
chr19_-_5986143 5.22 ENSMUST00000041827.7
solute carrier family 22 (organic anion transporter), member 20
chr2_+_164940742 5.22 ENSMUST00000137626.1
matrix metallopeptidase 9
chr13_-_66851513 5.13 ENSMUST00000169322.1
predicted gene, 17404
chr9_-_107985863 5.12 ENSMUST00000048568.4
family with sequence similarity 212, member A
chr7_+_43427622 5.04 ENSMUST00000177164.2
lens intrinsic membrane protein 2
chr1_+_86303221 5.03 ENSMUST00000113306.2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr11_+_72961163 5.02 ENSMUST00000108486.1
ENSMUST00000108484.1
ENSMUST00000021142.7
ENSMUST00000108485.2
ENSMUST00000163326.1
ATPase, Ca++ transporting, ubiquitous
chr9_-_44344159 4.98 ENSMUST00000077353.7
hydroxymethylbilane synthase
chrX_+_136666375 4.97 ENSMUST00000060904.4
ENSMUST00000113100.1
ENSMUST00000128040.1
transcription elongation factor A (SII)-like 3
chr15_+_101293196 4.90 ENSMUST00000071328.6
RIKEN cDNA 6030408B16 gene
chr7_+_43440782 4.89 ENSMUST00000040227.1
claudin domain containing 2
chr7_+_46861203 4.80 ENSMUST00000014545.4
lactate dehydrogenase C
chrX_-_162964557 4.77 ENSMUST00000038769.2
S100 calcium binding protein G
chr13_-_113100971 4.73 ENSMUST00000023897.5
granzyme A
chr2_-_34913976 4.71 ENSMUST00000028232.3
PHD finger protein 19
chr11_-_106998483 4.66 ENSMUST00000124541.1
karyopherin (importin) alpha 2
chr10_+_128908907 4.63 ENSMUST00000105229.1
CD63 antigen
chr4_-_43483696 4.62 ENSMUST00000030180.6
suppression inducing transmembrane adaptor 1
chr17_-_25727364 4.60 ENSMUST00000170070.1
ENSMUST00000048054.7
CTF18, chromosome transmission fidelity factor 18
chr9_+_111004811 4.59 ENSMUST00000080872.4
predicted gene 10030
chr11_+_101078411 4.59 ENSMUST00000019445.5
hydroxysteroid (17-beta) dehydrogenase 1
chr7_+_19291070 4.50 ENSMUST00000108468.3
reticulon 2 (Z-band associated protein)
chrX_-_9469288 4.50 ENSMUST00000015484.3
cytochrome b-245, beta polypeptide
chrX_-_136203637 4.45 ENSMUST00000151592.1
ENSMUST00000131510.1
ENSMUST00000066819.4
transcription elongation factor A (SII)-like 5
chr11_+_4236411 4.42 ENSMUST00000075221.2
oncostatin M
chr10_+_128238034 4.41 ENSMUST00000105245.2
timeless circadian clock 1
chr7_-_141655319 4.37 ENSMUST00000062451.7
mucin 6, gastric
chr11_-_102925086 4.36 ENSMUST00000021311.9
kinesin family member 18B
chr10_-_79788924 4.35 ENSMUST00000020573.6
protease, serine 57
chr7_-_133702515 4.32 ENSMUST00000153698.1
uroporphyrinogen III synthase
chr1_+_135232045 4.31 ENSMUST00000110798.3
predicted gene 4204
chr3_+_105870858 4.30 ENSMUST00000164730.1
adenosine A3 receptor
chr8_+_71406003 4.26 ENSMUST00000119976.1
ENSMUST00000120725.1
ankyrin repeat and LEM domain containing 1
chr1_-_93342734 4.24 ENSMUST00000027493.3
PAS domain containing serine/threonine kinase
chr6_+_40964760 4.22 ENSMUST00000076638.5
RIKEN cDNA 1810009J06 gene
chr7_-_110982443 4.15 ENSMUST00000005751.6
MRV integration site 1
chr18_+_34751803 4.14 ENSMUST00000181453.1
ENSMUST00000181641.1
RIKEN cDNA 2010110K18 gene
chr17_-_28942255 4.11 ENSMUST00000051526.4
peroxisomal, testis specific 1
chr13_+_120263114 4.09 ENSMUST00000181748.1
ENSMUST00000179905.1
cDNA sequence AF067061
chr11_-_102897146 4.08 ENSMUST00000077902.4
glial fibrillary acidic protein
chr11_+_44617310 4.08 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
early B cell factor 1
chr19_-_42086338 4.06 ENSMUST00000051772.8
MORN repeat containing 4
chr4_+_154011731 4.04 ENSMUST00000169622.1
ENSMUST00000030894.8
leucine rich repeat containing 47
chr2_+_101624734 4.01 ENSMUST00000111227.1
recombination activating gene 2
chr6_+_72544391 4.00 ENSMUST00000071044.6
ENSMUST00000114072.1
capping protein (actin filament), gelsolin-like
chr9_-_108190352 3.98 ENSMUST00000035208.7
bassoon
chr16_+_17276291 3.94 ENSMUST00000164950.1
ENSMUST00000159242.1
transmembrane protein 191C
chr6_-_122801639 3.94 ENSMUST00000165884.1
solute carrier family 2 (facilitated glucose transporter), member 3
chr16_+_17208135 3.91 ENSMUST00000169803.1
RIMS binding protein 3
chr7_-_19676749 3.79 ENSMUST00000003074.9
apolipoprotein C-II
chr7_-_128418154 3.77 ENSMUST00000033133.5
regulator of G-protein signalling 10
chr10_-_60696471 3.76 ENSMUST00000105461.3
ENSMUST00000105464.2
ENSMUST00000105463.2
cadherin 23 (otocadherin)
chr7_+_28440927 3.76 ENSMUST00000078845.6
glia maturation factor, gamma
chr16_-_57071346 3.75 ENSMUST00000067173.6
RIKEN cDNA 2310005G13 gene
chrX_-_164250368 3.70 ENSMUST00000112263.1
BMX non-receptor tyrosine kinase
chr5_-_100572192 3.69 ENSMUST00000031264.5
placenta-specific 8
chr8_-_121907678 3.68 ENSMUST00000045557.9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
chr3_-_152340350 3.68 ENSMUST00000073089.6
ENSMUST00000068243.6
family with sequence similarity 73, member A
chr5_+_47984793 3.67 ENSMUST00000170109.2
ENSMUST00000174421.1
ENSMUST00000173702.1
ENSMUST00000173107.1
slit homolog 2 (Drosophila)
chr7_-_38107490 3.66 ENSMUST00000108023.3
cyclin E1
chr1_+_166130238 3.65 ENSMUST00000060833.7
ENSMUST00000166159.1
glycoprotein A33 (transmembrane)
chr12_-_28582515 3.65 ENSMUST00000110917.1
ENSMUST00000020965.7
allantoicase
chr11_+_117782358 3.64 ENSMUST00000117781.1
transmembrane channel-like gene family 8
chr8_-_123983120 3.63 ENSMUST00000075578.6
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr16_+_10170228 3.61 ENSMUST00000044103.5
ribosomal protein L39-like
chr7_-_116084635 3.59 ENSMUST00000111755.3
predicted gene 4353
chr16_+_10170216 3.57 ENSMUST00000121292.1
ribosomal protein L39-like
chr14_+_65806066 3.57 ENSMUST00000139644.1
PDZ binding kinase
chr6_+_34354119 3.55 ENSMUST00000038406.6
aldo-keto reductase family 1, member B8
chr4_+_156109971 3.51 ENSMUST00000072554.6
ENSMUST00000169550.1
ENSMUST00000105576.1
RIKEN cDNA 9430015G10 gene
chr2_+_174415804 3.51 ENSMUST00000109075.1
ENSMUST00000016397.6
negative elongation factor complex member C/D, Th1l
chr12_+_87816577 3.51 ENSMUST00000110149.1
expressed sequence BB287469
chr17_+_6601671 3.49 ENSMUST00000092966.4
dynein light chain Tctex-type 1C
chr3_-_27896360 3.48 ENSMUST00000058077.3
transmembrane protein 212
chr11_+_32205411 3.48 ENSMUST00000039601.3
ENSMUST00000149043.1
small nuclear ribonucleoprotein 25 (U11/U12)
chr17_-_6655939 3.47 ENSMUST00000179554.1
dynein light chain Tctex-type 1F
chr15_-_89425856 3.46 ENSMUST00000109313.2
carnitine palmitoyltransferase 1b, muscle
chr6_-_83527452 3.44 ENSMUST00000141904.1
actin, gamma 2, smooth muscle, enteric
chr7_-_99238564 3.43 ENSMUST00000064231.7
monoacylglycerol O-acyltransferase 2
chr11_+_69966896 3.42 ENSMUST00000151515.1
claudin 7
chr11_+_96931387 3.41 ENSMUST00000107633.1
proline rich 15-like
chr10_+_128225830 3.36 ENSMUST00000026455.7
major intrinsic protein of eye lens fiber
chr4_-_116994354 3.34 ENSMUST00000130273.1
uroporphyrinogen decarboxylase
chr3_+_129878571 3.32 ENSMUST00000029629.8
phospholipase A2, group XIIA
chr5_+_110330697 3.32 ENSMUST00000112481.1
polymerase (DNA directed), epsilon
chr7_+_28267809 3.32 ENSMUST00000059596.6
EP300 interacting inhibitor of differentiation 2
chr7_-_30445508 3.30 ENSMUST00000006828.7
amyloid beta (A4) precursor-like protein 1
chr19_+_4154606 3.29 ENSMUST00000061086.8
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr6_+_113531675 3.28 ENSMUST00000036340.5
ENSMUST00000101051.2
Fanconi anemia, complementation group D2
chr7_-_118116171 3.27 ENSMUST00000131374.1
ribosomal protein S15A
chr7_-_25297866 3.27 ENSMUST00000148150.1
ENSMUST00000155118.1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr17_+_35067317 3.27 ENSMUST00000173478.1
ENSMUST00000174876.1
lymphocyte antigen 6 complex, locus G6C
chr7_+_17087934 3.25 ENSMUST00000152671.1
pregnancy specific glycoprotein 16
chr5_+_138280516 3.24 ENSMUST00000048028.8
stromal antigen 3
chr6_-_41446062 3.23 ENSMUST00000095999.5
predicted gene 10334
chr6_+_28427789 3.23 ENSMUST00000031719.6
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)
chr8_-_105707933 3.22 ENSMUST00000013299.9
enkurin domain containing 1
chr12_-_78980758 3.22 ENSMUST00000174072.1
transmembrane protein 229B

Network of associatons between targets according to the STRING database.

First level regulatory network of Pitx2_Otx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.4 31.3 GO:0030221 basophil differentiation(GO:0030221)
6.0 17.9 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
5.3 21.2 GO:0035524 proline transmembrane transport(GO:0035524)
4.7 14.1 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
4.3 13.0 GO:0015811 L-cystine transport(GO:0015811)
3.4 13.8 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
3.1 9.2 GO:0070488 neutrophil aggregation(GO:0070488)
3.1 9.2 GO:0071846 actin filament debranching(GO:0071846)
2.3 9.4 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
2.3 9.2 GO:0015825 L-serine transport(GO:0015825)
2.1 8.6 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
2.1 6.4 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
2.1 12.7 GO:0060931 sinoatrial node cell development(GO:0060931)
2.1 6.3 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
2.0 10.0 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
2.0 7.9 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
1.8 5.5 GO:0002879 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
1.8 9.1 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
1.8 5.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
1.8 5.3 GO:0001928 regulation of exocyst assembly(GO:0001928)
1.8 10.5 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
1.7 5.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
1.7 8.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.7 10.0 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
1.6 6.6 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
1.6 8.0 GO:1904970 brush border assembly(GO:1904970)
1.5 4.4 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
1.4 5.7 GO:1990743 protein sialylation(GO:1990743)
1.4 13.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.4 4.1 GO:0002358 B cell homeostatic proliferation(GO:0002358)
1.3 4.0 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
1.3 10.1 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
1.2 3.7 GO:0090260 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
1.2 12.1 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
1.2 3.6 GO:0006714 sesquiterpenoid metabolic process(GO:0006714)
1.2 3.5 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
1.1 5.6 GO:0019516 lactate oxidation(GO:0019516)
1.1 3.3 GO:0045004 DNA replication proofreading(GO:0045004)
1.1 6.6 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
1.1 3.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
1.1 3.3 GO:0071873 response to norepinephrine(GO:0071873)
1.1 4.2 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
1.0 6.3 GO:0002835 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
1.0 3.1 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
1.0 3.0 GO:0006597 spermine biosynthetic process(GO:0006597)
1.0 3.0 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
1.0 15.6 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.9 4.6 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.9 2.7 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.9 4.5 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.9 5.3 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.9 2.6 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.9 2.6 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.9 2.6 GO:0006434 seryl-tRNA aminoacylation(GO:0006434) negative regulation of vascular endothelial growth factor production(GO:1904046)
0.8 2.5 GO:1990523 bone regeneration(GO:1990523)
0.8 0.8 GO:0071035 nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.8 2.4 GO:0009726 detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726)
0.8 4.0 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.8 4.7 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.8 6.3 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.8 3.8 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.7 3.0 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.7 3.7 GO:2000359 regulation of binding of sperm to zona pellucida(GO:2000359)
0.7 2.2 GO:0036233 glycine import(GO:0036233)
0.7 4.3 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
0.7 18.7 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.7 8.5 GO:0015816 glycine transport(GO:0015816)
0.7 6.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.7 2.8 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.7 2.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.7 4.8 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.7 1.4 GO:0001802 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.7 1.3 GO:0015675 nickel cation transport(GO:0015675)
0.7 3.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.6 1.3 GO:0033189 response to vitamin A(GO:0033189)
0.6 8.9 GO:1904659 glucose transmembrane transport(GO:1904659)
0.6 6.2 GO:0030916 otic vesicle formation(GO:0030916)
0.6 3.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.6 2.4 GO:0033575 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.6 2.4 GO:1904747 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.6 1.8 GO:0002355 detection of tumor cell(GO:0002355)
0.6 10.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.6 22.1 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.6 2.9 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.6 5.2 GO:0071231 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.6 1.7 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.6 2.2 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.5 2.2 GO:2000426 TRIF-dependent toll-like receptor signaling pathway(GO:0035666) interleukin-4-mediated signaling pathway(GO:0035771) negative regulation of apoptotic cell clearance(GO:2000426)
0.5 2.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.5 3.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.5 2.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.5 7.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.5 4.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.5 11.3 GO:0042572 retinol metabolic process(GO:0042572)
0.5 12.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.5 2.0 GO:0061153 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895)
0.5 5.5 GO:0071294 cellular response to zinc ion(GO:0071294)
0.5 3.9 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.5 3.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.5 2.4 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.5 2.8 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.5 1.8 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.5 1.8 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.5 4.1 GO:1904714 chaperone-mediated autophagy(GO:0061684) regulation of chaperone-mediated autophagy(GO:1904714)
0.5 2.3 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.4 1.3 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.4 1.7 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.4 2.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.4 1.2 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.4 1.2 GO:0036292 DNA rewinding(GO:0036292)
0.4 2.0 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087) regulation of ovarian follicle development(GO:2000354)
0.4 2.0 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.4 4.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.4 1.5 GO:1902896 terminal web assembly(GO:1902896)
0.4 1.2 GO:1901355 response to rapamycin(GO:1901355)
0.4 1.9 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.4 2.6 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.4 3.8 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.4 0.4 GO:0097503 sialylation(GO:0097503)
0.4 1.5 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.4 5.2 GO:0015747 urate transport(GO:0015747)
0.4 1.9 GO:0015966 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.4 0.4 GO:0042335 cuticle development(GO:0042335)
0.4 1.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.4 1.8 GO:0000103 sulfate assimilation(GO:0000103)
0.4 5.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.4 2.8 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.4 1.1 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.3 2.1 GO:0035026 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) leading edge cell differentiation(GO:0035026)
0.3 2.4 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.3 1.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.3 1.7 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.3 1.7 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.3 5.7 GO:0006999 nuclear pore organization(GO:0006999)
0.3 1.7 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.3 4.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.3 3.6 GO:0000255 allantoin metabolic process(GO:0000255)
0.3 1.0 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.3 3.0 GO:0048539 bone marrow development(GO:0048539)
0.3 3.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.3 3.3 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.3 1.3 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.3 1.3 GO:0061386 closure of optic fissure(GO:0061386)
0.3 1.6 GO:0009597 detection of virus(GO:0009597)
0.3 2.9 GO:0016180 snRNA processing(GO:0016180)
0.3 0.6 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.3 1.0 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.3 4.4 GO:0070269 pyroptosis(GO:0070269)
0.3 1.0 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.3 0.9 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.3 2.4 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.3 1.8 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.3 14.4 GO:0043029 T cell homeostasis(GO:0043029)
0.3 4.1 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.3 1.8 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.3 1.7 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.3 1.7 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.3 1.4 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.3 2.3 GO:0016139 fucose metabolic process(GO:0006004) glycoside catabolic process(GO:0016139)
0.3 3.7 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.3 1.7 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.3 2.2 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.3 2.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.3 4.8 GO:0046599 regulation of centriole replication(GO:0046599)
0.3 0.8 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
0.3 1.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.3 1.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 8.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 2.6 GO:1902969 mitotic DNA replication(GO:1902969)
0.3 3.1 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.3 0.8 GO:1904980 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.3 2.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 1.2 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.2 0.5 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) negative regulation of hypersensitivity(GO:0002884)
0.2 0.7 GO:0009233 menaquinone metabolic process(GO:0009233)
0.2 2.2 GO:0008343 adult feeding behavior(GO:0008343)
0.2 5.4 GO:0031297 replication fork processing(GO:0031297)
0.2 1.0 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 2.5 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.2 6.6 GO:0006270 DNA replication initiation(GO:0006270)
0.2 0.7 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.2 1.2 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.2 0.5 GO:0090172 microtubule cytoskeleton organization involved in homologous chromosome segregation(GO:0090172)
0.2 1.9 GO:0019532 oxalate transport(GO:0019532)
0.2 0.5 GO:0032849 regulation of cellular pH reduction(GO:0032847) positive regulation of cellular pH reduction(GO:0032849)
0.2 0.5 GO:0002344 B cell selection(GO:0002339) peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.2 0.9 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.2 1.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 0.9 GO:0035547 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.2 0.9 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.2 0.7 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 1.3 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.2 0.4 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.2 1.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.2 0.6 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.2 1.4 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 0.6 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.2 5.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 0.8 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.2 1.6 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.2 1.0 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.2 0.8 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.2 0.8 GO:0043137 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.2 1.4 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.2 3.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 0.4 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.2 0.8 GO:0030576 Cajal body organization(GO:0030576)
0.2 1.3 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.2 1.1 GO:0018094 protein polyglycylation(GO:0018094)
0.2 1.5 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.2 1.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.2 2.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 2.0 GO:2001204 regulation of osteoclast development(GO:2001204)
0.2 4.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 1.4 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 2.8 GO:0015804 neutral amino acid transport(GO:0015804)
0.2 0.9 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.2 1.8 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.2 1.8 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 1.4 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.2 0.7 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 3.5 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.2 0.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.2 0.7 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.2 2.8 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.2 1.0 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.2 1.5 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.2 3.4 GO:0006833 water transport(GO:0006833)
0.2 2.7 GO:0030049 muscle filament sliding(GO:0030049)
0.2 6.4 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.2 1.6 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.2 0.3 GO:0032499 detection of peptidoglycan(GO:0032499) negative regulation of interleukin-18 production(GO:0032701) negative regulation of toll-like receptor 2 signaling pathway(GO:0034136)
0.2 1.4 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.2 7.1 GO:0016572 histone phosphorylation(GO:0016572)
0.2 0.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 1.1 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832)
0.2 1.5 GO:0035878 nail development(GO:0035878)
0.2 5.5 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.2 0.9 GO:0034227 tRNA thio-modification(GO:0034227)
0.1 0.9 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 2.0 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.3 GO:1902336 positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.1 2.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 1.0 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.1 0.4 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.4 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 5.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 3.8 GO:0006706 steroid catabolic process(GO:0006706)
0.1 0.8 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.1 0.6 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 0.8 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 0.6 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 0.4 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 0.4 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 1.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 2.0 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 1.0 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.1 0.8 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 1.5 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 1.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 1.4 GO:0097435 fibril organization(GO:0097435)
0.1 5.0 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.1 0.8 GO:0051025 negative regulation of immunoglobulin secretion(GO:0051025)
0.1 0.7 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 1.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 1.3 GO:0098953 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 3.3 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 6.2 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 1.8 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.5 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.1 0.6 GO:0036005 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.1 4.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.2 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1 0.3 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.1 0.8 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 3.0 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 2.0 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 3.9 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 4.2 GO:0007140 male meiosis(GO:0007140)
0.1 5.0 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.5 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.1 1.2 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.1 2.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 1.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.4 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.1 0.5 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 3.3 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.1 0.8 GO:1901799 negative regulation of proteasomal protein catabolic process(GO:1901799)
0.1 1.0 GO:0043485 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.1 5.4 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.3 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 2.0 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 2.7 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.1 0.6 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.1 1.0 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.4 GO:0009624 response to nematode(GO:0009624)
0.1 0.6 GO:0071280 cellular response to copper ion(GO:0071280)
0.1 1.0 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 1.9 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.2 GO:0021764 amygdala development(GO:0021764)
0.1 10.5 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.2 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 1.6 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 0.7 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 2.7 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.1 0.9 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 1.6 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 2.0 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.3 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 1.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.7 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 0.1 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.1 1.3 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 0.2 GO:0071314 cellular response to cocaine(GO:0071314)
0.1 0.5 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 4.8 GO:0001824 blastocyst development(GO:0001824)
0.1 0.5 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 1.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 0.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.5 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.5 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 1.6 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 1.6 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.6 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.5 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.5 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.1 1.6 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.1 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.8 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.5 GO:0006449 regulation of translational termination(GO:0006449)
0.1 3.1 GO:0016925 protein sumoylation(GO:0016925)
0.1 1.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 3.4 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 1.2 GO:0030225 macrophage differentiation(GO:0030225)
0.1 0.3 GO:0046103 ADP biosynthetic process(GO:0006172) inosine biosynthetic process(GO:0046103)
0.1 3.0 GO:0007088 regulation of mitotic nuclear division(GO:0007088)
0.1 1.2 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.8 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.3 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.5 GO:2000809 nerve growth factor signaling pathway(GO:0038180) neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 3.7 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 3.5 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 0.6 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 0.6 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.4 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.8 GO:1990089 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0 0.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.5 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.0 1.7 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.3 GO:0097421 liver regeneration(GO:0097421)
0.0 0.4 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 4.0 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 1.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.0 2.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.1 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 1.2 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 3.8 GO:0007030 Golgi organization(GO:0007030)
0.0 5.8 GO:0008360 regulation of cell shape(GO:0008360)
0.0 1.2 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 3.0 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 1.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.0 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.2 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.5 GO:0070849 response to epidermal growth factor(GO:0070849) cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 1.7 GO:0046324 regulation of glucose import(GO:0046324)
0.0 1.2 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 1.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:0009068 aspartate family amino acid catabolic process(GO:0009068)
0.0 0.3 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.8 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.9 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.3 GO:2000582 regulation of microtubule motor activity(GO:2000574) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0007398 ectoderm development(GO:0007398)
0.0 1.5 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 0.4 GO:0042993 positive regulation of transcription factor import into nucleus(GO:0042993)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.3 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.0 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 1.0 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.1 GO:0016598 protein arginylation(GO:0016598)
0.0 4.2 GO:0043588 skin development(GO:0043588)
0.0 0.5 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.8 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.5 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 2.7 GO:0009566 fertilization(GO:0009566)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.8 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.4 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.4 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.5 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 1.0 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 2.1 GO:0032496 response to lipopolysaccharide(GO:0032496)
0.0 1.2 GO:0031497 chromatin assembly(GO:0031497)
0.0 0.4 GO:0042509 regulation of tyrosine phosphorylation of STAT protein(GO:0042509)
0.0 0.3 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.6 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.1 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 1.4 GO:0021915 neural tube development(GO:0021915)
0.0 0.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 17.9 GO:0031095 platelet dense tubular network membrane(GO:0031095)
2.8 13.8 GO:0032444 activin responsive factor complex(GO:0032444)
2.4 19.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.8 5.4 GO:0035101 FACT complex(GO:0035101)
1.5 4.6 GO:0046691 intracellular canaliculus(GO:0046691)
1.5 4.4 GO:0034774 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
1.3 4.0 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
1.2 4.6 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
1.1 9.0 GO:0001940 male pronucleus(GO:0001940)
1.1 4.5 GO:0014802 terminal cisterna(GO:0014802)
1.0 3.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
1.0 4.1 GO:0097450 astrocyte end-foot(GO:0097450)
1.0 3.9 GO:0032021 NELF complex(GO:0032021)
0.9 5.6 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.9 16.8 GO:0005652 nuclear lamina(GO:0005652)
0.9 4.4 GO:0000235 astral microtubule(GO:0000235)
0.8 16.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.8 11.5 GO:0044754 autolysosome(GO:0044754)
0.8 8.0 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.8 13.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.7 2.9 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.7 6.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.7 2.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.7 3.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.6 4.4 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.6 1.8 GO:0000811 GINS complex(GO:0000811)
0.6 1.7 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.5 2.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.5 7.8 GO:0032039 integrator complex(GO:0032039)
0.5 2.4 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.5 2.9 GO:1990393 3M complex(GO:1990393)
0.5 1.9 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.5 6.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.5 36.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.5 6.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.4 4.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.4 2.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.4 1.8 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.4 6.5 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.4 12.1 GO:0001891 phagocytic cup(GO:0001891)
0.4 0.8 GO:0070557 PCNA-p21 complex(GO:0070557)
0.4 20.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.4 3.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.4 1.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.4 42.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 3.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.3 3.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 1.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.3 11.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.3 1.0 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.3 1.3 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.3 1.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.3 3.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.3 1.2 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.3 2.0 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 2.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 4.0 GO:0090543 Flemming body(GO:0090543)
0.3 5.1 GO:0032426 stereocilium tip(GO:0032426)
0.3 8.2 GO:0097228 sperm principal piece(GO:0097228)
0.3 0.8 GO:1990047 spindle matrix(GO:1990047)
0.3 2.9 GO:0036156 inner dynein arm(GO:0036156)
0.3 0.5 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.2 1.2 GO:0071797 LUBAC complex(GO:0071797)
0.2 1.2 GO:0044316 cone cell pedicle(GO:0044316)
0.2 1.7 GO:0019815 B cell receptor complex(GO:0019815)
0.2 1.7 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 1.7 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 3.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2 1.4 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 2.8 GO:0042575 DNA polymerase complex(GO:0042575)
0.2 2.6 GO:0005688 U6 snRNP(GO:0005688)
0.2 1.8 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 2.1 GO:0031415 NatA complex(GO:0031415)
0.2 2.4 GO:0042629 mast cell granule(GO:0042629)
0.2 5.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 5.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 1.5 GO:0005796 Golgi lumen(GO:0005796)
0.2 1.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 10.6 GO:0005871 kinesin complex(GO:0005871)
0.2 2.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 1.7 GO:0002177 manchette(GO:0002177)
0.2 3.6 GO:0005686 U2 snRNP(GO:0005686)
0.2 0.7 GO:0030891 VCB complex(GO:0030891)
0.2 1.8 GO:0042788 polysomal ribosome(GO:0042788)
0.2 1.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 3.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 0.8 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 1.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.0 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 1.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 2.8 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.3 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 3.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 2.3 GO:0031528 microvillus membrane(GO:0031528)
0.1 15.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 2.1 GO:0000974 Prp19 complex(GO:0000974)
0.1 0.8 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 1.3 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 1.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.4 GO:0000814 ESCRT II complex(GO:0000814)
0.1 1.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.5 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.6 GO:0071914 prominosome(GO:0071914)
0.1 1.0 GO:0042382 paraspeckles(GO:0042382)
0.1 0.7 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 1.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.8 GO:0033202 DNA helicase complex(GO:0033202)
0.1 0.9 GO:0070652 HAUS complex(GO:0070652)
0.1 1.3 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 1.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 2.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 2.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 6.3 GO:0031941 filamentous actin(GO:0031941)
0.1 0.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 1.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 4.3 GO:0015030 Cajal body(GO:0015030)
0.1 1.5 GO:0032433 filopodium tip(GO:0032433)
0.1 0.4 GO:0016342 catenin complex(GO:0016342)
0.1 4.5 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 2.1 GO:0030914 STAGA complex(GO:0030914)
0.1 0.6 GO:0070847 core mediator complex(GO:0070847)
0.1 0.6 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.5 GO:0033010 paranodal junction(GO:0033010)
0.1 3.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 2.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 8.4 GO:0031526 brush border membrane(GO:0031526)
0.1 1.5 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 2.9 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.8 GO:0032009 early phagosome(GO:0032009)
0.1 0.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 1.2 GO:0005916 fascia adherens(GO:0005916)
0.1 2.0 GO:0043596 nuclear replication fork(GO:0043596)
0.1 4.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 5.7 GO:0005643 nuclear pore(GO:0005643)
0.1 1.0 GO:0042555 MCM complex(GO:0042555)
0.1 3.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 1.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 2.1 GO:0032982 myosin filament(GO:0032982)
0.1 16.5 GO:0031965 nuclear membrane(GO:0031965)
0.1 0.7 GO:0031209 SCAR complex(GO:0031209)
0.1 6.8 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 2.4 GO:0043198 dendritic shaft(GO:0043198)
0.1 4.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.3 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 0.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 3.1 GO:0034704 calcium channel complex(GO:0034704)
0.1 5.7 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 7.5 GO:0042383 sarcolemma(GO:0042383)
0.1 1.4 GO:0014704 intercalated disc(GO:0014704)
0.1 0.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 72.8 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 1.4 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.1 GO:0000791 euchromatin(GO:0000791)
0.1 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 1.2 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 1.2 GO:0001741 XY body(GO:0001741)
0.1 1.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 4.6 GO:0016605 PML body(GO:0016605)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 5.5 GO:0031514 motile cilium(GO:0031514)
0.0 1.2 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 11.1 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.7 GO:0030686 90S preribosome(GO:0030686)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 3.7 GO:0043679 axon terminus(GO:0043679)
0.0 6.8 GO:0005925 focal adhesion(GO:0005925)
0.0 2.1 GO:0005814 centriole(GO:0005814)
0.0 1.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.3 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 2.0 GO:0005840 ribosome(GO:0005840)
0.0 1.3 GO:0000776 kinetochore(GO:0000776)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.0 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 13.0 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
3.9 15.6 GO:0004566 beta-glucuronidase activity(GO:0004566)
3.3 10.0 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
2.1 6.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
2.0 10.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
2.0 31.7 GO:0008301 DNA binding, bending(GO:0008301)
2.0 13.7 GO:0016936 galactoside binding(GO:0016936)
1.7 16.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.6 6.6 GO:0004568 chitinase activity(GO:0004568)
1.5 9.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
1.5 4.6 GO:0070401 NADP+ binding(GO:0070401)
1.5 12.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
1.5 10.5 GO:0050786 RAGE receptor binding(GO:0050786)
1.4 5.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
1.3 9.4 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
1.3 7.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
1.2 1.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
1.2 6.2 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
1.2 6.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
1.2 6.0 GO:0030171 voltage-gated proton channel activity(GO:0030171)
1.1 12.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
1.1 7.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
1.1 8.6 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
1.0 13.9 GO:0003688 DNA replication origin binding(GO:0003688)
1.0 3.0 GO:0090556 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
1.0 8.8 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.0 5.7 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
1.0 8.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.9 6.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.9 5.5 GO:0042731 PH domain binding(GO:0042731)
0.9 2.6 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.8 3.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.8 2.3 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.7 8.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.7 2.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.7 9.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.7 2.8 GO:0004074 biliverdin reductase activity(GO:0004074)
0.7 3.4 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.7 4.8 GO:0005499 vitamin D binding(GO:0005499)
0.7 1.3 GO:0015099 nickel cation transmembrane transporter activity(GO:0015099)
0.7 11.1 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.6 5.8 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.6 1.8 GO:0036004 GAF domain binding(GO:0036004)
0.6 7.0 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.6 2.9 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.6 4.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.6 4.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.5 1.6 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.5 3.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.5 8.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.5 3.6 GO:0001758 retinal dehydrogenase activity(GO:0001758) alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.5 7.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.5 13.1 GO:0070410 co-SMAD binding(GO:0070410)
0.5 1.4 GO:0004948 calcitonin receptor activity(GO:0004948)
0.5 1.9 GO:0038025 reelin receptor activity(GO:0038025)
0.5 2.4 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.5 9.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.4 12.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.4 1.3 GO:0032190 acrosin binding(GO:0032190)
0.4 1.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.4 2.5 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.4 1.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.4 1.7 GO:0050436 microfibril binding(GO:0050436)
0.4 5.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.4 3.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.4 14.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.4 2.4 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.4 1.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.4 1.1 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.4 4.9 GO:0016004 phospholipase activator activity(GO:0016004)
0.4 2.2 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.4 1.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.4 2.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.4 14.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.4 2.1 GO:0004985 opioid receptor activity(GO:0004985)
0.4 2.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.3 5.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 2.7 GO:0001849 complement component C1q binding(GO:0001849)
0.3 1.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.3 2.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3 7.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 1.0 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.3 4.5 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.3 1.0 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.3 2.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.3 1.6 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.3 1.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.3 0.9 GO:0098770 FBXO family protein binding(GO:0098770)
0.3 4.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.3 1.8 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.3 1.5 GO:0008422 beta-glucosidase activity(GO:0008422)
0.3 3.0 GO:0016918 retinal binding(GO:0016918)
0.3 13.3 GO:0030552 cAMP binding(GO:0030552)
0.3 2.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.3 1.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.3 6.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.3 1.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.3 1.7 GO:0097016 L27 domain binding(GO:0097016)
0.3 1.4 GO:0030620 U2 snRNA binding(GO:0030620)
0.3 1.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.3 16.9 GO:0030507 spectrin binding(GO:0030507)
0.3 1.4 GO:0019770 IgG receptor activity(GO:0019770)
0.3 3.5 GO:0050897 cobalt ion binding(GO:0050897)
0.3 7.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.3 3.7 GO:0002162 dystroglycan binding(GO:0002162)
0.3 1.8 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.3 0.8 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.3 46.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 2.0 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.3 5.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 2.7 GO:0051870 methotrexate binding(GO:0051870)
0.2 1.5 GO:0019211 phosphatase activator activity(GO:0019211)
0.2 1.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 1.7 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 1.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 0.7 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.2 6.4 GO:0045503 dynein light chain binding(GO:0045503)
0.2 1.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.2 6.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 1.8 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 2.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 0.9 GO:0004802 transketolase activity(GO:0004802)
0.2 2.5 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.2 1.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 6.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 0.6 GO:0034618 arginine binding(GO:0034618)
0.2 4.2 GO:0030275 LRR domain binding(GO:0030275)
0.2 5.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 12.0 GO:0004521 endoribonuclease activity(GO:0004521)
0.2 9.2 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.2 0.8 GO:0016842 amidine-lyase activity(GO:0016842)
0.2 1.4 GO:0019808 polyamine binding(GO:0019808)
0.2 4.7 GO:0031005 filamin binding(GO:0031005)
0.2 1.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.2 0.8 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.2 0.4 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.2 0.8 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 0.6 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.2 5.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 1.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 0.5 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.2 6.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 2.1 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 4.7 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.2 2.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 0.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 1.3 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 0.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 12.1 GO:0097110 scaffold protein binding(GO:0097110)
0.2 2.1 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 1.8 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 9.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 7.2 GO:0050699 WW domain binding(GO:0050699)
0.2 0.8 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2 1.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.9 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 1.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 3.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 1.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 1.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.6 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 3.2 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 1.2 GO:0003691 double-stranded telomeric DNA binding(GO:0003691) 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 1.0 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 3.9 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 3.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 6.6 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.8 GO:0000150 recombinase activity(GO:0000150)
0.1 0.4 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.5 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 1.3 GO:0051434 BH3 domain binding(GO:0051434)
0.1 2.8 GO:0043274 phospholipase binding(GO:0043274)
0.1 4.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 2.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.4 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.4 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.5 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 1.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.6 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 0.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.2 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.3 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1 3.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 3.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 2.1 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 1.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 3.1 GO:0008198 ferrous iron binding(GO:0008198)
0.1 1.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.9 GO:0008494 translation activator activity(GO:0008494)
0.1 3.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.3 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 0.5 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 2.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 2.6 GO:0005550 pheromone binding(GO:0005550)
0.1 2.1 GO:0000146 microfilament motor activity(GO:0000146)
0.1 3.5 GO:0003777 microtubule motor activity(GO:0003777)
0.1 2.1 GO:0034061 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.1 1.9 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 2.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 1.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 2.6 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.1 1.0 GO:0043495 protein anchor(GO:0043495)
0.1 0.3 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 3.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 3.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.2 GO:0048185 activin binding(GO:0048185)
0.1 1.2 GO:0030551 cyclic nucleotide binding(GO:0030551)
0.1 0.5 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 1.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.9 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 0.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 7.8 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 0.9 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.4 GO:0016594 glycine binding(GO:0016594)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.4 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 2.3 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.1 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.1 3.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 1.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 4.1 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 1.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.1 1.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 4.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 2.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.2 GO:0070840 dynein complex binding(GO:0070840)
0.1 3.1 GO:0005518 collagen binding(GO:0005518)
0.1 3.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 2.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.5 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 0.2 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 9.8 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.4 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 1.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 1.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.0 1.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.7 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 1.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0034212 peptide N-acetyltransferase activity(GO:0034212)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 3.0 GO:0004519 endonuclease activity(GO:0004519)
0.0 18.9 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.7 GO:0000049 tRNA binding(GO:0000049)
0.0 2.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 1.8 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0 0.6 GO:0001848 complement binding(GO:0001848)
0.0 1.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.0 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 2.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 2.1 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 6.2 GO:0004866 endopeptidase inhibitor activity(GO:0004866) endopeptidase regulator activity(GO:0061135)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 3.0 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 3.7 GO:0042393 histone binding(GO:0042393)
0.0 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 2.0 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.7 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 1.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.8 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.5 GO:0004620 phospholipase activity(GO:0004620)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 9.5 GO:0003682 chromatin binding(GO:0003682)
0.0 0.1 GO:0035586 purinergic receptor activity(GO:0035586)
0.0 8.9 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 2.4 GO:0051015 actin filament binding(GO:0051015)
0.0 2.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 3.1 GO:0008017 microtubule binding(GO:0008017)
0.0 0.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.6 GO:0046332 SMAD binding(GO:0046332)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 2.8 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 3.7 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.5 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.2 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 11.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5 25.5 PID ATR PATHWAY ATR signaling pathway
0.5 50.1 PID P73PATHWAY p73 transcription factor network
0.5 10.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.4 11.2 PID CONE PATHWAY Visual signal transduction: Cones
0.4 15.8 PID AURORA A PATHWAY Aurora A signaling
0.3 2.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3 14.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3 9.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 6.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 7.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 12.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 11.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 5.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 5.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 4.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 6.8 PID AURORA B PATHWAY Aurora B signaling
0.2 5.7 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.2 8.0 ST GA13 PATHWAY G alpha 13 Pathway
0.2 1.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 6.2 PID BMP PATHWAY BMP receptor signaling
0.1 4.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 4.4 PID IL3 PATHWAY IL3-mediated signaling events
0.1 11.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 10.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 5.5 PID E2F PATHWAY E2F transcription factor network
0.1 1.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 3.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 5.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 8.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 3.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 5.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 1.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 5.7 PID P53 REGULATION PATHWAY p53 pathway
0.1 2.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 21.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 4.2 PID FGF PATHWAY FGF signaling pathway
0.1 1.8 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 1.3 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 1.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 2.6 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.8 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 5.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 0.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 0.8 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 0.5 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.2 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 7.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 18.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
1.0 15.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.9 5.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.8 39.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.8 17.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.6 12.8 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.6 13.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.6 17.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.6 12.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.5 9.0 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.5 5.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.5 48.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.4 1.7 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.4 11.4 REACTOME KINESINS Genes involved in Kinesins
0.4 21.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.4 16.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 3.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.4 9.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.4 2.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.3 17.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.3 8.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 33.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.3 5.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.3 2.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.3 3.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 5.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.3 5.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.3 7.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 3.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 1.8 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 9.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 5.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 10.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 1.9 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.2 9.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 3.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.2 0.9 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.2 3.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 2.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 13.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 7.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 4.8 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 3.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 6.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 2.9 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.1 1.7 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 10.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 2.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 8.6 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 3.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 2.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 4.9 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 5.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 5.4 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.1 2.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 4.2 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 2.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 8.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 2.0 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.3 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.4 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 5.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.0 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 2.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.5 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.1 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex