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GSE58827: Dynamics of the Mouse Liver

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Results for Pknox2_Pknox1

Z-value: 0.71

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Transcription factors associated with Pknox2_Pknox1

Gene Symbol Gene ID Gene Info
Pknox2
ENSMUSG00000035934.9 Pbx/knotted 1 homeobox 2
Pknox1
ENSMUSG00000006705.6 Pbx/knotted 1 homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pknox1mm10_v2_chr17_+_31564749_315648540.202.4e-01Click!
Pknox2mm10_v2_chr9_-_37147257_37147323-0.144.3e-01Click!

Activity profile of Pknox2_Pknox1 motif

Sorted Z-values of Pknox2_Pknox1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_66945019 4.60 ENSMUST00000027151.5
Myl1
myosin, light polypeptide 1
chr1_-_66945361 3.80 ENSMUST00000160100.1
Myl1
myosin, light polypeptide 1
chr1_+_136052804 1.95 ENSMUST00000112064.1
Cacna1s
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr1_+_136052750 1.91 ENSMUST00000160641.1
Cacna1s
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr1_+_136052771 1.88 ENSMUST00000112068.3
Cacna1s
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr2_-_76982455 1.68 ENSMUST00000011934.5
ENSMUST00000099981.2
ENSMUST00000099980.3
ENSMUST00000111882.2
ENSMUST00000140091.1
Ttn
titin
chr9_-_31913462 1.44 ENSMUST00000116615.3
Barx2
BarH-like homeobox 2
chr7_-_131410325 1.16 ENSMUST00000154602.1
Ikzf5
IKAROS family zinc finger 5
chr1_-_87101590 1.16 ENSMUST00000113270.2
Alpi
alkaline phosphatase, intestinal
chr5_-_138619653 1.00 ENSMUST00000129832.1
Zfp68
zinc finger protein 68
chr2_+_152911311 0.96 ENSMUST00000028970.7
Mylk2
myosin, light polypeptide kinase 2, skeletal muscle
chr17_-_48432723 0.83 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr10_-_123196916 0.79 ENSMUST00000020334.7
Usp15
ubiquitin specific peptidase 15
chr1_+_87124946 0.77 ENSMUST00000044878.3
Akp3
alkaline phosphatase 3, intestine, not Mn requiring
chr5_-_138619751 0.74 ENSMUST00000085852.4
ENSMUST00000110905.2
Zfp68
zinc finger protein 68
chr2_+_162987502 0.74 ENSMUST00000117123.1
Sgk2
serum/glucocorticoid regulated kinase 2
chr7_-_131410495 0.73 ENSMUST00000121033.1
ENSMUST00000046306.8
Ikzf5
IKAROS family zinc finger 5
chr16_-_11176056 0.71 ENSMUST00000142389.1
ENSMUST00000138185.1
Zc3h7a
zinc finger CCCH type containing 7 A
chr18_+_49832622 0.70 ENSMUST00000180611.1
Dmxl1
Dmx-like 1
chr3_+_107631322 0.69 ENSMUST00000106703.1
Gm10961
predicted gene 10961
chr2_+_162987330 0.66 ENSMUST00000018012.7
Sgk2
serum/glucocorticoid regulated kinase 2
chr10_-_7792795 0.64 ENSMUST00000065124.1
6530403G13Rik
RIKEN cDNA 6530403G13 gene
chr5_-_138619702 0.64 ENSMUST00000063262.4
Zfp68
zinc finger protein 68
chr9_+_113930934 0.63 ENSMUST00000084885.5
ENSMUST00000009885.7
Ubp1
upstream binding protein 1
chr6_-_106800051 0.59 ENSMUST00000013882.7
ENSMUST00000049675.4
ENSMUST00000113239.3
Crbn
cereblon
chr7_-_48881032 0.59 ENSMUST00000058745.8
E2f8
E2F transcription factor 8
chr2_-_132578128 0.58 ENSMUST00000028822.7
Gpcpd1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr17_-_24141542 0.57 ENSMUST00000115411.1
ENSMUST00000115409.2
ENSMUST00000115407.2
ENSMUST00000102927.3
Pdpk1
3-phosphoinositide dependent protein kinase 1
chr2_-_132578244 0.57 ENSMUST00000110142.1
Gpcpd1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr8_+_20136455 0.52 ENSMUST00000179299.1
ENSMUST00000096485.4
Gm21811
predicted gene, 21811
chr10_+_50592669 0.52 ENSMUST00000035606.8
Ascc3
activating signal cointegrator 1 complex subunit 3
chr8_+_3655762 0.51 ENSMUST00000012849.8
ENSMUST00000169234.2
Retn
resistin
chr12_-_24493656 0.50 ENSMUST00000073088.2
Gm16372
predicted pseudogene 16372
chrX_+_49463926 0.49 ENSMUST00000130558.1
Arhgap36
Rho GTPase activating protein 36
chr5_+_93268247 0.48 ENSMUST00000121127.1
Ccng2
cyclin G2
chr13_-_24206281 0.48 ENSMUST00000123076.1
Lrrc16a
leucine rich repeat containing 16A
chr2_-_132578155 0.46 ENSMUST00000110136.1
ENSMUST00000124107.1
ENSMUST00000060955.5
Gpcpd1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr8_+_19682268 0.44 ENSMUST00000153710.1
ENSMUST00000127799.1
Gm6483
predicted gene 6483
chr2_+_130012336 0.44 ENSMUST00000110299.2
Tgm3
transglutaminase 3, E polypeptide
chr9_+_123366921 0.42 ENSMUST00000038863.7
Lars2
leucyl-tRNA synthetase, mitochondrial
chr2_-_113758638 0.41 ENSMUST00000099575.3
Grem1
gremlin 1
chrX_-_109013389 0.39 ENSMUST00000033597.8
Hmgn5
high-mobility group nucleosome binding domain 5
chr10_+_7792891 0.38 ENSMUST00000015901.4
Ppil4
peptidylprolyl isomerase (cyclophilin)-like 4
chr1_-_179546261 0.37 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr14_+_54640952 0.36 ENSMUST00000169818.2
Gm17606
predicted gene, 17606
chr8_+_25601591 0.36 ENSMUST00000155861.1
Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr11_+_78324200 0.34 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr6_-_71262232 0.34 ENSMUST00000129630.2
ENSMUST00000114186.2
ENSMUST00000074301.3
Smyd1
SET and MYND domain containing 1
chr17_-_66077022 0.33 ENSMUST00000150766.1
ENSMUST00000038116.5
Ankrd12
ankyrin repeat domain 12
chr9_+_67840386 0.32 ENSMUST00000077879.5
Vps13c
vacuolar protein sorting 13C (yeast)
chr10_+_34297421 0.32 ENSMUST00000047935.6
Tspyl4
TSPY-like 4
chr5_-_71548190 0.31 ENSMUST00000050129.5
Cox7b2
cytochrome c oxidase subunit VIIb2
chr5_-_100500592 0.31 ENSMUST00000149714.1
ENSMUST00000046154.5
Lin54
lin-54 homolog (C. elegans)
chr10_+_41810528 0.30 ENSMUST00000099931.3
Sesn1
sestrin 1
chr18_+_63708689 0.30 ENSMUST00000072726.5
Wdr7
WD repeat domain 7
chr7_-_48881596 0.30 ENSMUST00000119223.1
E2f8
E2F transcription factor 8
chr19_-_44069690 0.29 ENSMUST00000169092.1
Erlin1
ER lipid raft associated 1
chr10_-_62651194 0.29 ENSMUST00000020270.4
Ddx50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr8_-_111522073 0.29 ENSMUST00000034437.6
ENSMUST00000038193.7
Wdr59
WD repeat domain 59
chr1_-_180195902 0.28 ENSMUST00000161746.1
Adck3
aarF domain containing kinase 3
chr10_-_42276688 0.27 ENSMUST00000175881.1
ENSMUST00000056974.3
Foxo3
forkhead box O3
chr6_-_48445373 0.26 ENSMUST00000114563.1
ENSMUST00000114558.1
ENSMUST00000101443.3
ENSMUST00000114564.1
Zfp467
zinc finger protein 467
chr11_+_23256001 0.26 ENSMUST00000020538.6
ENSMUST00000109551.1
ENSMUST00000102870.1
ENSMUST00000102869.1
Xpo1
exportin 1, CRM1 homolog (yeast)
chr3_-_51560816 0.26 ENSMUST00000037141.7
Setd7
SET domain containing (lysine methyltransferase) 7
chr2_+_146855861 0.26 ENSMUST00000099278.2
ENSMUST00000156232.1
Plk1s1
polo-like kinase 1 substrate 1
chr7_+_13398115 0.26 ENSMUST00000005791.7
Cabp5
calcium binding protein 5
chr1_-_58973421 0.25 ENSMUST00000173590.1
ENSMUST00000027186.5
Trak2
trafficking protein, kinesin binding 2
chr2_-_160872829 0.24 ENSMUST00000176141.1
Zhx3
zinc fingers and homeoboxes 3
chr13_+_109685994 0.24 ENSMUST00000074103.5
Pde4d
phosphodiesterase 4D, cAMP specific
chr8_+_56294552 0.23 ENSMUST00000034026.8
Hpgd
hydroxyprostaglandin dehydrogenase 15 (NAD)
chr13_+_46669517 0.23 ENSMUST00000099547.3
C78339
expressed sequence C78339
chr11_-_78386558 0.23 ENSMUST00000108294.1
Foxn1
forkhead box N1
chr11_-_98022594 0.22 ENSMUST00000103144.3
ENSMUST00000017552.6
ENSMUST00000092736.4
ENSMUST00000107562.1
Cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr15_-_81843699 0.22 ENSMUST00000092020.2
Gm8444
predicted gene 8444
chr16_+_23107413 0.22 ENSMUST00000023599.6
ENSMUST00000168891.1
Eif4a2
eukaryotic translation initiation factor 4A2
chr10_-_42276744 0.21 ENSMUST00000105502.1
ENSMUST00000105501.1
Foxo3
forkhead box O3
chr15_+_99591028 0.21 ENSMUST00000169082.1
Aqp5
aquaporin 5
chr3_-_79567679 0.20 ENSMUST00000076136.4
Fnip2
folliculin interacting protein 2
chr19_+_6047081 0.19 ENSMUST00000025723.8
Syvn1
synovial apoptosis inhibitor 1, synoviolin
chr5_-_25498702 0.19 ENSMUST00000173073.1
ENSMUST00000045291.7
Kmt2c
lysine (K)-specific methyltransferase 2C
chr13_-_58274121 0.19 ENSMUST00000091579.4
Gkap1
G kinase anchoring protein 1
chr4_+_106911517 0.18 ENSMUST00000072753.6
ENSMUST00000097934.3
Ssbp3
single-stranded DNA binding protein 3
chr11_+_3202908 0.18 ENSMUST00000179770.1
ENSMUST00000110048.1
Eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr3_+_116594959 0.18 ENSMUST00000029571.8
Sass6
spindle assembly 6 homolog (C. elegans)
chr14_+_55575617 0.17 ENSMUST00000022826.5
Fitm1
fat storage-inducing transmembrane protein 1
chr19_+_6047055 0.17 ENSMUST00000134667.1
Syvn1
synovial apoptosis inhibitor 1, synoviolin
chr1_+_85793411 0.17 ENSMUST00000113360.1
ENSMUST00000126962.1
Cab39
calcium binding protein 39
chr5_+_137553517 0.16 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
Actl6b
actin-like 6B
chr4_+_11758147 0.16 ENSMUST00000029871.5
ENSMUST00000108303.1
Cdh17
cadherin 17
chr6_+_95117740 0.16 ENSMUST00000032107.7
ENSMUST00000119582.1
Kbtbd8
kelch repeat and BTB (POZ) domain containing 8
chr9_-_71771535 0.15 ENSMUST00000122065.1
ENSMUST00000121322.1
ENSMUST00000072899.2
Cgnl1
cingulin-like 1
chr8_+_47824459 0.15 ENSMUST00000038693.6
Cldn22
claudin 22
chr16_-_43979050 0.15 ENSMUST00000165648.1
ENSMUST00000036321.7
Zdhhc23
zinc finger, DHHC domain containing 23
chr19_-_44069526 0.14 ENSMUST00000170801.1
Erlin1
ER lipid raft associated 1
chr2_-_160872985 0.14 ENSMUST00000109460.1
ENSMUST00000127201.1
Zhx3
zinc fingers and homeoboxes 3
chr19_+_11965817 0.14 ENSMUST00000025590.9
Osbp
oxysterol binding protein
chr1_-_74588117 0.14 ENSMUST00000066986.6
Zfp142
zinc finger protein 142
chr13_-_12106945 0.14 ENSMUST00000021750.7
ENSMUST00000170156.2
Ryr2
ryanodine receptor 2, cardiac
chr4_-_47010781 0.13 ENSMUST00000135777.1
Gm568
predicted gene 568
chr8_+_55940453 0.13 ENSMUST00000000275.7
Glra3
glycine receptor, alpha 3 subunit
chr9_-_82975475 0.13 ENSMUST00000034787.5
Phip
pleckstrin homology domain interacting protein
chr1_+_156558759 0.12 ENSMUST00000173929.1
Abl2
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chr19_-_44069736 0.12 ENSMUST00000172041.1
ENSMUST00000071698.6
ENSMUST00000112028.3
Erlin1
ER lipid raft associated 1
chr7_+_112225856 0.12 ENSMUST00000050149.5
ENSMUST00000106647.1
ENSMUST00000106648.1
Mical2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr17_+_23898717 0.12 ENSMUST00000088598.5
Dcpp2
demilune cell and parotid protein 2
chr11_-_80080928 0.11 ENSMUST00000103233.3
ENSMUST00000061283.8
Crlf3
cytokine receptor-like factor 3
chr4_-_155043143 0.11 ENSMUST00000135665.2
Plch2
phospholipase C, eta 2
chr18_+_56432116 0.10 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr3_-_84270782 0.10 ENSMUST00000054990.4
Trim2
tripartite motif-containing 2
chrX_-_60893430 0.10 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr3_+_51415986 0.10 ENSMUST00000029303.7
Naa15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr17_+_30624354 0.09 ENSMUST00000170651.1
Dnah8
dynein, axonemal, heavy chain 8
chr11_-_49712674 0.09 ENSMUST00000020624.6
ENSMUST00000145353.1
Cnot6
CCR4-NOT transcription complex, subunit 6
chr10_+_82699007 0.09 ENSMUST00000020478.7
Hcfc2
host cell factor C2
chr2_-_91649751 0.08 ENSMUST00000099714.3
Zfp408
zinc finger protein 408
chr4_+_106911470 0.08 ENSMUST00000030367.8
ENSMUST00000149926.1
Ssbp3
single-stranded DNA binding protein 3
chr1_-_52727457 0.08 ENSMUST00000156876.1
ENSMUST00000087701.3
Mfsd6
major facilitator superfamily domain containing 6
chr11_+_72796254 0.08 ENSMUST00000069395.5
Zzef1
zinc finger, ZZ-type with EF hand domain 1
chr7_-_126584578 0.08 ENSMUST00000150311.1
Cln3
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr11_-_72796028 0.08 ENSMUST00000156294.1
Cyb5d2
cytochrome b5 domain containing 2
chr8_+_76899772 0.08 ENSMUST00000109913.2
Nr3c2
nuclear receptor subfamily 3, group C, member 2
chr6_-_48445678 0.07 ENSMUST00000114556.1
Zfp467
zinc finger protein 467
chr11_+_83964419 0.07 ENSMUST00000049714.8
ENSMUST00000092834.5
ENSMUST00000183714.1
ENSMUST00000183456.1
Synrg
synergin, gamma
chr16_+_55973881 0.06 ENSMUST00000050248.8
Rpl24
ribosomal protein L24
chr1_+_58973521 0.06 ENSMUST00000114296.1
ENSMUST00000027185.4
Stradb
STE20-related kinase adaptor beta
chr5_+_138820080 0.06 ENSMUST00000179205.1
Gm5294
predicted gene 5294
chr7_+_98703091 0.06 ENSMUST00000033009.9
Prkrir
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr2_+_111780313 0.06 ENSMUST00000054004.1
Olfr1302
olfactory receptor 1302
chr11_-_72795801 0.06 ENSMUST00000079681.5
Cyb5d2
cytochrome b5 domain containing 2
chr8_+_94386486 0.06 ENSMUST00000034220.7
Herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr2_+_153492790 0.06 ENSMUST00000109783.1
4930404H24Rik
RIKEN cDNA 4930404H24 gene
chr7_+_25221417 0.06 ENSMUST00000055604.4
Zfp526
zinc finger protein 526
chr8_-_91134027 0.06 ENSMUST00000125257.1
Aktip
thymoma viral proto-oncogene 1 interacting protein
chr1_+_106938953 0.05 ENSMUST00000112724.2
Serpinb12
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12
chr3_-_89402650 0.05 ENSMUST00000168325.1
ENSMUST00000057431.5
Lenep
lens epithelial protein
chr2_-_91649785 0.05 ENSMUST00000111333.1
Zfp408
zinc finger protein 408
chr9_+_107928440 0.04 ENSMUST00000085073.1
Actl11
actin-like 11
chr8_-_91133942 0.04 ENSMUST00000120213.1
ENSMUST00000109609.2
Aktip
thymoma viral proto-oncogene 1 interacting protein
chrX_-_102505359 0.04 ENSMUST00000087916.4
Hdac8
histone deacetylase 8
chr11_+_72796164 0.04 ENSMUST00000172220.1
Zzef1
zinc finger, ZZ-type with EF hand domain 1
chr11_-_4594750 0.04 ENSMUST00000109943.3
Mtmr3
myotubularin related protein 3
chr7_+_13398150 0.04 ENSMUST00000117400.1
Cabp5
calcium binding protein 5
chr1_-_36244245 0.04 ENSMUST00000046875.7
Uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr9_+_68653761 0.03 ENSMUST00000034766.7
Rora
RAR-related orphan receptor alpha
chr5_-_122779278 0.03 ENSMUST00000111668.3
Camkk2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr3_-_108445183 0.03 ENSMUST00000090553.5
ENSMUST00000153499.1
Sars
seryl-aminoacyl-tRNA synthetase
chr17_+_35533194 0.02 ENSMUST00000025273.8
Psors1c2
psoriasis susceptibility 1 candidate 2 (human)
chr2_+_128967383 0.02 ENSMUST00000110320.2
ENSMUST00000110319.2
Zc3h6
zinc finger CCCH type containing 6
chr9_+_21424984 0.02 ENSMUST00000172482.1
ENSMUST00000174050.1
Dnm2
dynamin 2
chr17_+_23917455 0.02 ENSMUST00000115428.1
Dcpp3
demilune cell and parotid protein 3
chr19_+_32757497 0.01 ENSMUST00000013807.7
Pten
phosphatase and tensin homolog
chr15_-_59374149 0.01 ENSMUST00000022976.4
E430025E21Rik
RIKEN cDNA E430025E21 gene
chr7_-_126584220 0.01 ENSMUST00000128970.1
ENSMUST00000116269.2
Cln3
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr6_-_48445825 0.01 ENSMUST00000114561.2
Zfp467
zinc finger protein 467
chr18_+_40256960 0.01 ENSMUST00000096572.1
2900055J20Rik
RIKEN cDNA 2900055J20 gene
chr6_+_88724489 0.01 ENSMUST00000113581.1
Mgll
monoglyceride lipase
chr11_+_99857915 0.01 ENSMUST00000107434.1
Gm11568
predicted gene 11568
chr4_-_119218165 0.00 ENSMUST00000030394.2
4930538K18Rik
RIKEN cDNA 4930538K18 gene

Network of associatons between targets according to the STRING database.

First level regulatory network of Pknox2_Pknox1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.7 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.4 1.7 GO:0043056 forward locomotion(GO:0043056)
0.3 0.9 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.2 1.0 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.2 0.4 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.2 0.5 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.2 0.8 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 1.4 GO:0042637 catagen(GO:0042637)
0.1 1.6 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.3 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.8 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.2 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 0.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.5 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.1 0.7 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.6 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.0 0.3 GO:1904923 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734) negative regulation of macromitophagy(GO:1901525) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.0 0.6 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 8.6 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 0.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.4 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.8 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.6 GO:0006972 hyperosmotic response(GO:0006972)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.0 0.3 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:2000327 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 0.4 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.2 GO:0007567 parturition(GO:0007567)
0.0 0.0 GO:1901630 negative regulation of presynaptic membrane organization(GO:1901630)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.0 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.4 GO:0031424 keratinization(GO:0031424)
0.0 1.3 GO:0032411 positive regulation of transporter activity(GO:0032411)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 10.2 GO:0016459 myosin complex(GO:0016459)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.6 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.3 6.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 1.9 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 1.7 GO:0031433 telethonin binding(GO:0031433)
0.1 0.8 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.0 GO:0032027 myosin light chain kinase activity(GO:0004687) myosin light chain binding(GO:0032027)
0.1 0.8 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 1.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.5 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.6 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 9.1 GO:0005509 calcium ion binding(GO:0005509)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 6.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.1 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.4 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis