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GSE58827: Dynamics of the Mouse Liver

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Results for Plagl1

Z-value: 0.76

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Transcription factors associated with Plagl1

Gene Symbol Gene ID Gene Info
Plagl1
ENSMUSG00000019817.12 pleiomorphic adenoma gene-like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Plagl1mm10_v2_chr10_+_13090788_13090843-0.828.2e-10Click!

Activity profile of Plagl1 motif

Sorted Z-values of Plagl1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_99695809 6.01 ENSMUST00000107086.2
Slco2b1
solute carrier organic anion transporter family, member 2b1
chr8_-_93079965 5.14 ENSMUST00000109582.1
Ces1b
carboxylesterase 1B
chr17_-_84682932 4.60 ENSMUST00000066175.3
Abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr15_+_75993756 4.19 ENSMUST00000089669.4
Mapk15
mitogen-activated protein kinase 15
chr19_+_4711153 3.48 ENSMUST00000008991.6
Sptbn2
spectrin beta, non-erythrocytic 2
chr4_+_47288057 3.13 ENSMUST00000140413.1
ENSMUST00000107731.2
Col15a1
collagen, type XV, alpha 1
chr3_-_108017806 3.13 ENSMUST00000126593.1
Gstm1
glutathione S-transferase, mu 1
chr4_+_47288287 3.12 ENSMUST00000146967.1
Col15a1
collagen, type XV, alpha 1
chr4_-_104876383 3.05 ENSMUST00000064873.8
ENSMUST00000106808.3
ENSMUST00000048947.8
C8a
complement component 8, alpha polypeptide
chr11_-_120727226 2.96 ENSMUST00000106148.3
ENSMUST00000026144.4
Dcxr
dicarbonyl L-xylulose reductase
chr17_+_79626669 2.90 ENSMUST00000086570.1
4921513D11Rik
RIKEN cDNA 4921513D11 gene
chr15_-_50890396 2.87 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr3_-_108017877 2.71 ENSMUST00000004140.4
Gstm1
glutathione S-transferase, mu 1
chr17_+_84683131 2.67 ENSMUST00000171915.1
Abcg8
ATP-binding cassette, sub-family G (WHITE), member 8
chr17_+_84683113 2.59 ENSMUST00000045714.8
Abcg8
ATP-binding cassette, sub-family G (WHITE), member 8
chr5_+_137981512 2.50 ENSMUST00000035390.5
Azgp1
alpha-2-glycoprotein 1, zinc
chr5_-_34187670 2.34 ENSMUST00000042701.6
ENSMUST00000119171.1
Mxd4
Max dimerization protein 4
chrX_-_75874536 2.32 ENSMUST00000033547.7
Pls3
plastin 3 (T-isoform)
chr2_-_3419019 2.25 ENSMUST00000115084.1
ENSMUST00000115083.1
Meig1
meiosis expressed gene 1
chr19_+_6497772 2.23 ENSMUST00000113458.1
ENSMUST00000113459.1
Nrxn2
neurexin II
chr5_-_87538188 2.17 ENSMUST00000031199.4
Sult1b1
sulfotransferase family 1B, member 1
chr5_+_125475814 1.89 ENSMUST00000031445.3
Aacs
acetoacetyl-CoA synthetase
chr2_-_3419066 1.88 ENSMUST00000115082.3
Meig1
meiosis expressed gene 1
chr17_+_24736639 1.77 ENSMUST00000115262.1
Msrb1
methionine sulfoxide reductase B1
chr17_+_37193889 1.75 ENSMUST00000038844.6
Ubd
ubiquitin D
chr17_+_24736673 1.61 ENSMUST00000101800.5
Msrb1
methionine sulfoxide reductase B1
chr2_+_25428699 1.57 ENSMUST00000102919.3
Abca2
ATP-binding cassette, sub-family A (ABC1), member 2
chr8_-_13974715 1.56 ENSMUST00000119182.1
ENSMUST00000062613.4
Tdrp
testis development related protein
chr5_-_120467296 1.41 ENSMUST00000132916.1
Sdsl
serine dehydratase-like
chr3_-_107239707 1.39 ENSMUST00000049852.8
Prok1
prokineticin 1
chr10_-_95415484 1.38 ENSMUST00000172070.1
ENSMUST00000150432.1
Socs2
suppressor of cytokine signaling 2
chr4_-_130275213 1.38 ENSMUST00000122374.1
Serinc2
serine incorporator 2
chrX_-_19237841 1.31 ENSMUST00000180592.1
Gm26652
predicted gene, 26652
chr2_-_130642770 1.21 ENSMUST00000045761.6
Lzts3
leucine zipper, putative tumor suppressor family member 3
chr1_-_179546261 1.13 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr17_-_24644933 1.12 ENSMUST00000019684.5
Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr4_+_148160613 1.12 ENSMUST00000047951.8
Fbxo2
F-box protein 2
chr5_+_24393640 1.10 ENSMUST00000138168.1
ENSMUST00000115077.1
Abcb8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr6_-_128438673 1.07 ENSMUST00000032508.4
Fkbp4
FK506 binding protein 4
chr12_-_56535047 1.05 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr1_-_131279544 1.04 ENSMUST00000062108.3
Ikbke
inhibitor of kappaB kinase epsilon
chr5_-_136567242 1.03 ENSMUST00000175975.2
ENSMUST00000176216.2
ENSMUST00000176745.1
Cux1
cut-like homeobox 1
chr12_-_103443653 1.03 ENSMUST00000055071.8
Ifi27l2a
interferon, alpha-inducible protein 27 like 2A
chr13_-_35027077 1.01 ENSMUST00000170538.1
ENSMUST00000163280.1
Eci2
enoyl-Coenzyme A delta isomerase 2
chr4_+_106561027 1.01 ENSMUST00000047973.3
Dhcr24
24-dehydrocholesterol reductase
chr12_+_59129757 1.00 ENSMUST00000069430.8
ENSMUST00000177370.1
Ctage5
CTAGE family, member 5
chr1_-_120074023 0.98 ENSMUST00000056089.7
Tmem37
transmembrane protein 37
chr18_-_61400363 0.98 ENSMUST00000063307.5
ENSMUST00000075299.6
Ppargc1b
peroxisome proliferative activated receptor, gamma, coactivator 1 beta
chr13_-_74350206 0.97 ENSMUST00000022062.7
Sdha
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr16_-_56717182 0.94 ENSMUST00000141404.1
Tfg
Trk-fused gene
chr4_-_22488296 0.93 ENSMUST00000178174.1
Pou3f2
POU domain, class 3, transcription factor 2
chr17_-_25868727 0.90 ENSMUST00000026828.5
Fam195a
family with sequence similarity 195, member A
chr1_+_162639148 0.87 ENSMUST00000028020.9
Myoc
myocilin
chr16_-_56717286 0.87 ENSMUST00000121554.1
ENSMUST00000128551.1
Tfg
Trk-fused gene
chr5_-_123012874 0.85 ENSMUST00000172729.1
Kdm2b
lysine (K)-specific demethylase 2B
chr6_-_134887783 0.85 ENSMUST00000066107.6
Gpr19
G protein-coupled receptor 19
chr16_+_10488175 0.84 ENSMUST00000023147.6
Ciita
class II transactivator
chr9_+_108662098 0.82 ENSMUST00000035222.5
Slc25a20
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
chr9_+_62342059 0.81 ENSMUST00000135395.1
Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr12_+_59129720 0.81 ENSMUST00000175912.1
ENSMUST00000176892.1
Ctage5
CTAGE family, member 5
chr10_-_95415283 0.80 ENSMUST00000119917.1
Socs2
suppressor of cytokine signaling 2
chr10_-_81350389 0.79 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
Hmg20b
high mobility group 20B
chr10_+_99420522 0.79 ENSMUST00000060657.2
B530045E10Rik
RIKEN cDNA B530045E10 gene
chr9_+_46273064 0.78 ENSMUST00000156440.1
ENSMUST00000034583.6
ENSMUST00000114552.3
Zfp259
zinc finger protein 259
chrX_+_99821021 0.78 ENSMUST00000096363.2
Tmem28
transmembrane protein 28
chr7_+_5015466 0.78 ENSMUST00000086349.3
Zfp524
zinc finger protein 524
chr5_+_35041539 0.76 ENSMUST00000030985.6
Hgfac
hepatocyte growth factor activator
chr10_-_81350305 0.76 ENSMUST00000167481.1
Hmg20b
high mobility group 20B
chr5_-_92083667 0.75 ENSMUST00000113127.3
G3bp2
GTPase activating protein (SH3 domain) binding protein 2
chr4_-_45489794 0.72 ENSMUST00000146236.1
Shb
src homology 2 domain-containing transforming protein B
chr1_+_74588347 0.71 ENSMUST00000113732.1
Bcs1l
BCS1-like (yeast)
chr9_+_57998036 0.71 ENSMUST00000181289.1
Gm17322
predicted gene, 17322
chr5_-_92083455 0.70 ENSMUST00000169094.1
ENSMUST00000167918.1
G3bp2
GTPase activating protein (SH3 domain) binding protein 2
chr2_-_65567505 0.69 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr4_+_155249960 0.68 ENSMUST00000178473.1
ENSMUST00000105627.1
ENSMUST00000097747.2
2610002J02Rik
RIKEN cDNA 2610002J02 gene
chr6_-_91807318 0.65 ENSMUST00000159684.1
Grip2
glutamate receptor interacting protein 2
chr6_-_91807424 0.63 ENSMUST00000162300.1
Grip2
glutamate receptor interacting protein 2
chr10_+_38965515 0.62 ENSMUST00000019992.5
Lama4
laminin, alpha 4
chr1_-_5019342 0.61 ENSMUST00000002533.8
Rgs20
regulator of G-protein signaling 20
chr17_+_35126316 0.61 ENSMUST00000061859.6
D17H6S53E
DNA segment, Chr 17, human D6S53E
chr12_+_100199435 0.61 ENSMUST00000110082.3
Calm1
calmodulin 1
chr9_+_102506072 0.59 ENSMUST00000039390.4
Ky
kyphoscoliosis peptidase
chr1_+_74588289 0.59 ENSMUST00000113733.3
ENSMUST00000027358.4
Bcs1l
BCS1-like (yeast)
chr6_-_128200598 0.59 ENSMUST00000071101.6
Gm10010
predicted gene 10010
chr2_-_132145057 0.58 ENSMUST00000028815.8
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr9_+_62342449 0.57 ENSMUST00000156461.1
Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chrX_+_120290259 0.56 ENSMUST00000113358.3
ENSMUST00000050239.9
ENSMUST00000113364.3
Pcdh11x
protocadherin 11 X-linked
chr5_-_134456227 0.55 ENSMUST00000111244.1
Gtf2ird1
general transcription factor II I repeat domain-containing 1
chr1_-_59094885 0.55 ENSMUST00000097080.3
Als2cr11
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11 (human)
chr18_-_38601268 0.54 ENSMUST00000025295.6
Spry4
sprouty homolog 4 (Drosophila)
chr7_+_45872772 0.54 ENSMUST00000002855.5
ENSMUST00000107719.1
Kdelr1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr6_-_48086530 0.53 ENSMUST00000073124.6
Zfp746
zinc finger protein 746
chr5_-_143269958 0.52 ENSMUST00000161448.1
Zfp316
zinc finger protein 316
chr9_-_59486610 0.51 ENSMUST00000171975.1
Arih1
ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)
chr8_+_20615097 0.51 ENSMUST00000178438.1
Gm21119
predicted gene, 21119
chr4_-_134203004 0.50 ENSMUST00000097849.2
Gm7534
predicted gene 7534
chr11_+_67966442 0.48 ENSMUST00000021286.4
ENSMUST00000108675.1
Stx8
syntaxin 8
chr8_+_20828015 0.48 ENSMUST00000178524.1
Gm20946
predicted gene, 20946
chr5_-_124352233 0.46 ENSMUST00000111472.1
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr8_-_20363210 0.45 ENSMUST00000084046.5
Gm15319
predicted gene 15319
chr8_-_40634776 0.44 ENSMUST00000048898.10
ENSMUST00000174205.1
Mtmr7
myotubularin related protein 7
chr17_-_29549588 0.43 ENSMUST00000114683.2
ENSMUST00000168339.1
Tmem217
transmembrane protein 217
chr1_-_52490736 0.42 ENSMUST00000170269.1
Nab1
Ngfi-A binding protein 1
chr7_+_15882617 0.42 ENSMUST00000125993.1
ENSMUST00000130566.1
Crxos1
Crx opposite strand transcript 1
chr9_+_108953597 0.41 ENSMUST00000026740.5
Col7a1
collagen, type VII, alpha 1
chr3_+_83007850 0.40 ENSMUST00000048486.7
Fgg
fibrinogen gamma chain
chr16_-_34262830 0.40 ENSMUST00000114947.1
Kalrn
kalirin, RhoGEF kinase
chr5_-_86676346 0.37 ENSMUST00000038448.6
Tmprss11bnl
transmembrane protease, serine 11b N terminal like
chr5_+_119834663 0.36 ENSMUST00000018407.6
Tbx5
T-box 5
chr8_+_19729746 0.35 ENSMUST00000098909.3
4930467E23Rik
RIKEN cDNA 4930467E23 gene
chr10_-_82285278 0.35 ENSMUST00000171401.1
4932415D10Rik
RIKEN cDNA 4932415D10 gene
chr3_-_96727436 0.34 ENSMUST00000154679.1
Polr3c
polymerase (RNA) III (DNA directed) polypeptide C
chr7_+_142533012 0.33 ENSMUST00000038675.6
Mrpl23
mitochondrial ribosomal protein L23
chr14_+_64588112 0.32 ENSMUST00000181808.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr5_-_24577467 0.32 ENSMUST00000030795.8
Abcf2
ATP-binding cassette, sub-family F (GCN20), member 2
chr6_+_110645572 0.32 ENSMUST00000071076.6
ENSMUST00000172951.1
Grm7
glutamate receptor, metabotropic 7
chr9_+_108953578 0.31 ENSMUST00000112070.1
Col7a1
collagen, type VII, alpha 1
chr10_-_60831571 0.31 ENSMUST00000077925.5
Unc5b
unc-5 homolog B (C. elegans)
chr9_-_117251801 0.31 ENSMUST00000172564.1
Rbms3
RNA binding motif, single stranded interacting protein
chr12_+_110889231 0.31 ENSMUST00000169597.1
ENSMUST00000165978.1
Tecpr2
tectonin beta-propeller repeat containing 2
chr17_+_46297406 0.29 ENSMUST00000061722.6
ENSMUST00000166280.1
Dlk2
delta-like 2 homolog (Drosophila)
chr16_+_32099781 0.28 ENSMUST00000115168.2
Cep19
centrosomal protein 19
chr14_-_54864055 0.28 ENSMUST00000142283.2
Homez
homeodomain leucine zipper-encoding gene
chr4_+_129136948 0.27 ENSMUST00000102600.3
Fndc5
fibronectin type III domain containing 5
chr4_+_33132552 0.26 ENSMUST00000182186.1
Gabrr1
gamma-aminobutyric acid (GABA) C receptor, subunit rho 1
chr16_-_19706365 0.25 ENSMUST00000081880.5
Lamp3
lysosomal-associated membrane protein 3
chrX_+_36328353 0.24 ENSMUST00000016383.3
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr12_-_17324703 0.23 ENSMUST00000020884.9
ENSMUST00000095820.5
ENSMUST00000127185.1
Atp6v1c2
ATPase, H+ transporting, lysosomal V1 subunit C2
chr11_+_87699897 0.22 ENSMUST00000040089.4
Rnf43
ring finger protein 43
chr6_-_124712131 0.21 ENSMUST00000004379.5
Emg1
EMG1 nucleolar protein homolog (S. cerevisiae)
chr6_+_124712279 0.21 ENSMUST00000004375.9
Phb2
prohibitin 2
chr5_-_122264378 0.20 ENSMUST00000111738.3
Tctn1
tectonic family member 1
chr6_-_128143525 0.20 ENSMUST00000032503.5
ENSMUST00000112173.1
Tspan9
tetraspanin 9
chr15_-_78206391 0.19 ENSMUST00000120592.1
Pvalb
parvalbumin
chr5_-_103655744 0.19 ENSMUST00000120108.1
1700016H13Rik
RIKEN cDNA 1700016H13 gene
chr4_+_33132503 0.17 ENSMUST00000029947.5
Gabrr1
gamma-aminobutyric acid (GABA) C receptor, subunit rho 1
chr5_-_103655709 0.17 ENSMUST00000120688.1
ENSMUST00000134926.1
1700016H13Rik
RIKEN cDNA 1700016H13 gene
chr11_+_115334731 0.16 ENSMUST00000106543.1
ENSMUST00000019006.4
Otop3
otopetrin 3
chr6_+_42286709 0.15 ENSMUST00000163936.1
Clcn1
chloride channel 1
chr6_+_42286676 0.15 ENSMUST00000031894.6
Clcn1
chloride channel 1
chr2_+_86034765 0.15 ENSMUST00000062360.4
Olfr1033
olfactory receptor 1033
chr10_-_128547722 0.14 ENSMUST00000040572.3
Zc3h10
zinc finger CCCH type containing 10
chr2_-_155592567 0.14 ENSMUST00000155347.1
ENSMUST00000130881.1
ENSMUST00000079691.6
Gss
glutathione synthetase
chr16_-_32099697 0.14 ENSMUST00000155966.1
ENSMUST00000096109.4
Pigx
phosphatidylinositol glycan anchor biosynthesis, class X
chr6_+_40325471 0.13 ENSMUST00000031977.8
Agk
acylglycerol kinase
chr16_+_32099904 0.09 ENSMUST00000042869.6
Cep19
centrosomal protein 19
chr11_-_120047144 0.09 ENSMUST00000103020.1
Aatk
apoptosis-associated tyrosine kinase
chr9_+_106453838 0.07 ENSMUST00000024260.6
Pcbp4
poly(rC) binding protein 4
chr10_+_128377086 0.07 ENSMUST00000014642.3
Ankrd52
ankyrin repeat domain 52
chr12_-_103675464 0.06 ENSMUST00000095451.1
Gm46
predicted gene 46
chr2_-_65567465 0.06 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr10_-_81482655 0.04 ENSMUST00000120508.1
ENSMUST00000118763.1
Celf5
CUGBP, Elav-like family member 5
chr6_-_92481343 0.03 ENSMUST00000113445.1
Prickle2
prickle homolog 2 (Drosophila)
chr9_+_38930173 0.03 ENSMUST00000058789.5
Olfr930
olfactory receptor 930
chr2_-_104257400 0.03 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr2_-_25214616 0.02 ENSMUST00000043774.4
ENSMUST00000114363.1
4933433C11Rik
RIKEN cDNA 4933433C11 gene
chrX_-_123029669 0.01 ENSMUST00000165345.1
Gm17521
predicted gene, 17521
chr10_+_127501672 0.01 ENSMUST00000160019.1
ENSMUST00000160610.1
Stac3
SH3 and cysteine rich domain 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Plagl1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.9 GO:0060752 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
1.5 6.0 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
1.0 3.0 GO:0042732 D-xylose metabolic process(GO:0042732)
0.8 3.4 GO:0030091 protein repair(GO:0030091)
0.4 2.2 GO:0006068 ethanol catabolic process(GO:0006068)
0.3 1.0 GO:0021759 globus pallidus development(GO:0021759)
0.3 5.8 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.2 1.0 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.2 2.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 1.6 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.2 0.9 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.2 1.4 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.2 0.6 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.2 3.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 0.7 GO:0046684 response to pyrethroid(GO:0046684)
0.2 0.9 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 4.2 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.1 1.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 1.8 GO:0070842 aggresome assembly(GO:0070842)
0.1 3.5 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.1 0.4 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.1 2.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.6 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 1.3 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.1 2.9 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 0.8 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.1 2.3 GO:0051639 actin filament network formation(GO:0051639)
0.1 2.2 GO:0098596 vocal learning(GO:0042297) imitative learning(GO:0098596)
0.1 2.2 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 1.6 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.8 GO:0015879 carnitine transport(GO:0015879)
0.1 0.5 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 1.5 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.7 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.9 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.8 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 1.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 1.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 1.4 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.4 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.9 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 1.0 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.2 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.3 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.3 GO:0014850 response to muscle activity(GO:0014850)
0.0 1.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 1.9 GO:0007584 response to nutrient(GO:0007584)
0.0 4.1 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 0.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.4 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 1.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 1.4 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.5 GO:0008333 endosome to lysosome transport(GO:0008333)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.9 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.5 3.5 GO:0008091 spectrin(GO:0008091)
0.4 1.6 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.3 3.1 GO:0005579 membrane attack complex(GO:0005579)
0.2 1.0 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.2 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 6.6 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.9 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.1 0.5 GO:0097413 Lewy body(GO:0097413)
0.1 1.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 6.3 GO:0005604 basement membrane(GO:0005604)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 3.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.0 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.8 GO:0016235 aggresome(GO:0016235)
0.0 2.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.9 GO:0032420 stereocilium(GO:0032420)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 1.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.7 GO:0016605 PML body(GO:0016605)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.9 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 4.0 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.5 5.8 GO:0016151 nickel cation binding(GO:0016151)
0.5 1.4 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.4 2.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.4 2.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.3 9.9 GO:0017127 cholesterol transporter activity(GO:0017127)
0.3 1.0 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.3 6.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.3 1.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3 0.8 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.2 1.9 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.2 1.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.2 4.2 GO:0004707 MAP kinase activity(GO:0004707)
0.2 1.0 GO:0008384 NF-kappaB-inducing kinase activity(GO:0004704) IkappaB kinase activity(GO:0008384)
0.2 1.0 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.2 0.6 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.2 0.6 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 0.8 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 0.5 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.9 GO:0032027 myosin light chain binding(GO:0032027)
0.1 3.1 GO:0001848 complement binding(GO:0001848)
0.1 0.3 GO:0070905 serine binding(GO:0070905)
0.1 1.4 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 1.8 GO:0070628 proteasome binding(GO:0070628)
0.1 1.0 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 3.0 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.1 1.6 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.0 0.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 2.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 1.0 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.7 GO:0031402 sodium ion binding(GO:0031402)
0.0 1.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 5.1 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.9 GO:0071837 HMG box domain binding(GO:0071837)
0.0 2.9 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.0 GO:0030546 receptor activator activity(GO:0030546)
0.0 0.2 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 1.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 2.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 4.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 1.1 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.0 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.5 11.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 2.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 6.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 3.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 6.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 3.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 1.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 2.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.4 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.1 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 1.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression