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GSE58827: Dynamics of the Mouse Liver

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Results for Pou3f2

Z-value: 0.85

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Transcription factors associated with Pou3f2

Gene Symbol Gene ID Gene Info
Pou3f2
ENSMUSG00000095139.1 POU domain, class 3, transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou3f2mm10_v2_chr4_-_22488296_224883660.289.6e-02Click!

Activity profile of Pou3f2 motif

Sorted Z-values of Pou3f2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_41302265 5.78 ENSMUST00000031913.4
Try4
trypsin 4
chr2_-_62483637 4.04 ENSMUST00000136686.1
ENSMUST00000102733.3
Gcg
glucagon
chr7_-_142661858 3.57 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr6_+_41354105 3.11 ENSMUST00000072103.5
Try10
trypsin 10
chr8_+_21734490 2.45 ENSMUST00000080533.5
Defa24
defensin, alpha, 24
chr8_+_21391811 2.42 ENSMUST00000120874.3
Gm21002
predicted gene, 21002
chr7_+_13623967 2.21 ENSMUST00000108525.2
Sult2a5
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5
chr8_+_21529031 2.15 ENSMUST00000084041.3
Gm15308
predicted gene 15308
chr6_+_142298419 2.09 ENSMUST00000041993.2
Iapp
islet amyloid polypeptide
chr14_+_80000292 1.97 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr8_+_21509258 1.78 ENSMUST00000084042.3
Defa20
defensin, alpha, 20
chr8_+_21378560 1.57 ENSMUST00000170275.2
Defa2
defensin, alpha, 2
chrX_-_139085230 1.49 ENSMUST00000152457.1
Serpina7
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr18_+_5593566 1.48 ENSMUST00000160910.1
Zeb1
zinc finger E-box binding homeobox 1
chr6_+_40964760 1.35 ENSMUST00000076638.5
1810009J06Rik
RIKEN cDNA 1810009J06 gene
chrX_-_145505175 1.25 ENSMUST00000143610.1
Amot
angiomotin
chr5_-_148392810 1.21 ENSMUST00000138257.1
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chrX_-_139085211 1.20 ENSMUST00000033626.8
ENSMUST00000060824.3
Serpina7
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr7_+_75610038 1.14 ENSMUST00000125771.1
Akap13
A kinase (PRKA) anchor protein 13
chr3_+_88965812 1.09 ENSMUST00000090933.4
Ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr14_+_84443553 1.06 ENSMUST00000071370.5
Pcdh17
protocadherin 17
chr12_-_91384403 0.97 ENSMUST00000141429.1
Cep128
centrosomal protein 128
chr17_+_43389436 0.96 ENSMUST00000113599.1
Gpr116
G protein-coupled receptor 116
chrX_-_95166307 0.96 ENSMUST00000113873.2
ENSMUST00000113876.2
ENSMUST00000113885.1
ENSMUST00000113883.1
ENSMUST00000182001.1
ENSMUST00000113882.1
ENSMUST00000113878.1
ENSMUST00000182562.1
Arhgef9
CDC42 guanine nucleotide exchange factor (GEF) 9
chrX_+_96456362 0.95 ENSMUST00000079322.5
ENSMUST00000113838.1
Heph
hephaestin
chr14_-_103844173 0.94 ENSMUST00000022718.3
Ednrb
endothelin receptor type B
chr14_+_99046406 0.92 ENSMUST00000022656.6
Bora
bora, aurora kinase A activator
chr14_-_47418407 0.91 ENSMUST00000043296.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr14_+_32166104 0.84 ENSMUST00000164341.1
Ncoa4
nuclear receptor coactivator 4
chr14_-_103843685 0.81 ENSMUST00000172237.1
Ednrb
endothelin receptor type B
chr6_-_129740484 0.77 ENSMUST00000050385.5
Klri2
killer cell lectin-like receptor family I member 2
chr2_-_62573813 0.73 ENSMUST00000174234.1
ENSMUST00000000402.9
ENSMUST00000174448.1
Fap
fibroblast activation protein
chr3_-_36571952 0.71 ENSMUST00000029270.3
Ccna2
cyclin A2
chr3_-_30013388 0.71 ENSMUST00000108270.3
Mecom
MDS1 and EVI1 complex locus
chr13_-_21468474 0.70 ENSMUST00000068235.4
Nkapl
NFKB activating protein-like
chr10_-_68541842 0.70 ENSMUST00000020103.2
1700040L02Rik
RIKEN cDNA 1700040L02 gene
chr13_+_44840686 0.68 ENSMUST00000173906.1
Jarid2
jumonji, AT rich interactive domain 2
chr19_+_38930909 0.68 ENSMUST00000025965.5
Hells
helicase, lymphoid specific
chr1_+_34121250 0.66 ENSMUST00000183006.1
Dst
dystonin
chr3_+_84666192 0.65 ENSMUST00000107682.1
Tmem154
transmembrane protein 154
chr11_+_11487671 0.65 ENSMUST00000020410.4
4930415F15Rik
RIKEN cDNA 4930415F15 gene
chr8_+_21249713 0.64 ENSMUST00000098895.2
Gm15292
predicted gene 15292
chr18_+_37400845 0.63 ENSMUST00000057228.1
Pcdhb9
protocadherin beta 9
chr5_+_107497762 0.63 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik
RIKEN cDNA A830010M20 gene
chrX_-_165004829 0.63 ENSMUST00000114890.2
Gm17604
predicted gene, 17604
chr13_-_74376566 0.62 ENSMUST00000091481.2
Zfp72
zinc finger protein 72
chr1_+_74661794 0.62 ENSMUST00000129890.1
Ttll4
tubulin tyrosine ligase-like family, member 4
chr1_+_150392794 0.61 ENSMUST00000124973.2
Tpr
translocated promoter region
chr7_+_16781341 0.59 ENSMUST00000108496.2
Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr6_-_129913166 0.59 ENSMUST00000169901.2
ENSMUST00000167079.2
ENSMUST00000014683.6
Klra5
killer cell lectin-like receptor, subfamily A, member 5
chr5_+_86071734 0.57 ENSMUST00000031171.7
Stap1
signal transducing adaptor family member 1
chr12_+_69241832 0.57 ENSMUST00000063445.6
Klhdc1
kelch domain containing 1
chr11_-_99244058 0.56 ENSMUST00000103132.3
ENSMUST00000038214.6
Krt222
keratin 222
chr18_+_4920509 0.52 ENSMUST00000126977.1
Svil
supervillin
chr10_+_97479470 0.51 ENSMUST00000105287.3
Dcn
decorin
chr16_-_36784784 0.50 ENSMUST00000165531.1
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr11_+_23256001 0.50 ENSMUST00000020538.6
ENSMUST00000109551.1
ENSMUST00000102870.1
ENSMUST00000102869.1
Xpo1
exportin 1, CRM1 homolog (yeast)
chr16_-_76022266 0.50 ENSMUST00000114240.1
Samsn1
SAM domain, SH3 domain and nuclear localization signals, 1
chr2_-_136387929 0.50 ENSMUST00000035264.2
ENSMUST00000077200.3
Pak7
p21 protein (Cdc42/Rac)-activated kinase 7
chrX_-_145505136 0.49 ENSMUST00000112835.1
Amot
angiomotin
chr7_+_30699783 0.49 ENSMUST00000013227.7
2200002J24Rik
RIKEN cDNA 2200002J24 gene
chr13_+_25056206 0.49 ENSMUST00000069614.6
Dcdc2a
doublecortin domain containing 2a
chr12_+_51377560 0.49 ENSMUST00000021335.5
Scfd1
Sec1 family domain containing 1
chr1_-_52490736 0.48 ENSMUST00000170269.1
Nab1
Ngfi-A binding protein 1
chr7_-_128206346 0.47 ENSMUST00000033049.7
Cox6a2
cytochrome c oxidase subunit VIa polypeptide 2
chr1_+_161494649 0.45 ENSMUST00000086084.1
Tnfsf18
tumor necrosis factor (ligand) superfamily, member 18
chr5_+_14025305 0.44 ENSMUST00000073957.6
Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr19_-_4877882 0.44 ENSMUST00000006626.3
Actn3
actinin alpha 3
chr15_-_83149270 0.43 ENSMUST00000129372.1
Poldip3
polymerase (DNA-directed), delta interacting protein 3
chr16_+_44811733 0.42 ENSMUST00000176819.1
ENSMUST00000176321.1
Cd200r4
CD200 receptor 4
chr14_+_73138755 0.42 ENSMUST00000171070.1
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chrX_+_164419782 0.42 ENSMUST00000033754.7
Piga
phosphatidylinositol glycan anchor biosynthesis, class A
chr15_-_75238768 0.41 ENSMUST00000089689.3
Gm10238
predicted pseudogene 10238
chr8_+_21618183 0.40 ENSMUST00000074343.5
Defa26
defensin, alpha, 26
chr5_-_66054499 0.38 ENSMUST00000145625.1
Rbm47
RNA binding motif protein 47
chr2_-_60125651 0.37 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr12_-_31351368 0.37 ENSMUST00000110857.3
Dld
dihydrolipoamide dehydrogenase
chr14_+_79515618 0.35 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr6_-_30958990 0.35 ENSMUST00000101589.3
Klf14
Kruppel-like factor 14
chr16_-_36784924 0.35 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr1_+_74661714 0.33 ENSMUST00000042125.8
ENSMUST00000141119.1
Ttll4
tubulin tyrosine ligase-like family, member 4
chr13_+_108046411 0.33 ENSMUST00000095458.4
Smim15
small integral membrane protein 15
chr16_+_36875119 0.33 ENSMUST00000135406.1
ENSMUST00000114812.1
ENSMUST00000134616.1
ENSMUST00000023534.6
Golgb1
Golgb1
golgi autoantigen, golgin subfamily b, macrogolgin 1
golgi autoantigen, golgin subfamily b, macrogolgin 1
chr3_+_27984145 0.33 ENSMUST00000067757.4
Pld1
phospholipase D1
chr5_+_86804508 0.32 ENSMUST00000038384.7
Ythdc1
YTH domain containing 1
chr2_+_104590453 0.31 ENSMUST00000028599.7
Cstf3
cleavage stimulation factor, 3' pre-RNA, subunit 3
chr7_-_133015248 0.31 ENSMUST00000169570.1
Ctbp2
C-terminal binding protein 2
chr15_-_63997969 0.31 ENSMUST00000164532.1
Fam49b
family with sequence similarity 49, member B
chr4_-_149126688 0.31 ENSMUST00000030815.2
Cort
cortistatin
chr2_+_61593077 0.31 ENSMUST00000112495.1
ENSMUST00000112501.2
Tank
TRAF family member-associated Nf-kappa B activator
chr3_+_95929325 0.30 ENSMUST00000171368.1
ENSMUST00000168106.1
Anp32e
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr17_-_46032366 0.30 ENSMUST00000071648.5
ENSMUST00000142351.2
ENSMUST00000167860.1
Vegfa
vascular endothelial growth factor A
chr6_+_8209216 0.30 ENSMUST00000040017.7
Mios
missing oocyte, meiosis regulator, homolog (Drosophila)
chr2_+_80315461 0.30 ENSMUST00000028392.7
Dnajc10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr14_-_88471396 0.30 ENSMUST00000061628.5
Pcdh20
protocadherin 20
chr9_+_88581036 0.27 ENSMUST00000164661.2
Trim43a
tripartite motif-containing 43A
chr4_+_11758147 0.27 ENSMUST00000029871.5
ENSMUST00000108303.1
Cdh17
cadherin 17
chr14_-_73049107 0.27 ENSMUST00000044664.4
ENSMUST00000169168.1
Cysltr2
cysteinyl leukotriene receptor 2
chr3_+_95929246 0.26 ENSMUST00000165307.1
ENSMUST00000015893.6
Anp32e
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr13_+_96388294 0.26 ENSMUST00000099295.4
Poc5
POC5 centriolar protein homolog (Chlamydomonas)
chr2_-_62573905 0.26 ENSMUST00000102732.3
Fap
fibroblast activation protein
chr17_-_6449571 0.26 ENSMUST00000180035.1
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr6_+_24748325 0.26 ENSMUST00000031691.2
Hyal4
hyaluronoglucosaminidase 4
chr3_+_66985647 0.26 ENSMUST00000162362.1
ENSMUST00000065074.7
Rsrc1
arginine/serine-rich coiled-coil 1
chr8_+_21315546 0.25 ENSMUST00000168340.1
ENSMUST00000167683.2
Gm15299
predicted pseudogene 15299
chr5_+_107497718 0.25 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr4_-_108780503 0.24 ENSMUST00000106658.1
Zfyve9
zinc finger, FYVE domain containing 9
chr6_-_99632376 0.23 ENSMUST00000176255.1
Gm20696
predicted gene 20696
chr10_-_53630439 0.22 ENSMUST00000075540.5
Mcm9
minichromosome maintenance complex component 9
chr1_-_150392719 0.21 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
BC003331
cDNA sequence BC003331
chr3_+_66985947 0.20 ENSMUST00000161726.1
ENSMUST00000160504.1
Rsrc1
arginine/serine-rich coiled-coil 1
chr11_-_50931612 0.20 ENSMUST00000109124.3
Zfp354b
zinc finger protein 354B
chr3_+_66985680 0.20 ENSMUST00000065047.6
Rsrc1
arginine/serine-rich coiled-coil 1
chr12_+_71170589 0.20 ENSMUST00000129376.1
2700049A03Rik
RIKEN cDNA 2700049A03 gene
chr4_-_108780782 0.19 ENSMUST00000106657.1
Zfyve9
zinc finger, FYVE domain containing 9
chr19_+_60144682 0.19 ENSMUST00000065383.4
E330013P04Rik
RIKEN cDNA E330013P04 gene
chr18_-_43477764 0.19 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr3_+_66985700 0.18 ENSMUST00000046542.6
ENSMUST00000162693.1
Rsrc1
arginine/serine-rich coiled-coil 1
chr11_+_23256566 0.18 ENSMUST00000136235.1
Xpo1
exportin 1, CRM1 homolog (yeast)
chr7_+_104218787 0.17 ENSMUST00000098180.3
Trim6
tripartite motif-containing 6
chr3_-_51560816 0.14 ENSMUST00000037141.7
Setd7
SET domain containing (lysine methyltransferase) 7
chr11_+_70023905 0.14 ENSMUST00000124568.2
Dlg4
discs, large homolog 4 (Drosophila)
chr15_+_36179530 0.14 ENSMUST00000171205.1
Spag1
sperm associated antigen 1
chr10_+_56377300 0.13 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chr9_+_88839164 0.12 ENSMUST00000163255.2
Trim43c
tripartite motif-containing 43C
chr19_-_20390944 0.12 ENSMUST00000025561.7
Anxa1
annexin A1
chr6_+_34384218 0.12 ENSMUST00000038383.7
ENSMUST00000115051.1
Akr1b10
aldo-keto reductase family 1, member B10 (aldose reductase)
chr8_+_83608175 0.11 ENSMUST00000005620.8
Dnajb1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr6_+_30512283 0.11 ENSMUST00000031798.7
Ssmem1
serine-rich single-pass membrane protein 1
chr5_+_122284365 0.11 ENSMUST00000053426.8
Pptc7
PTC7 protein phosphatase homolog (S. cerevisiae)
chr2_-_79908428 0.09 ENSMUST00000102652.3
ENSMUST00000102651.3
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr1_-_162813926 0.08 ENSMUST00000144916.1
ENSMUST00000140274.1
Fmo4
flavin containing monooxygenase 4
chr9_-_105521147 0.08 ENSMUST00000176770.1
ENSMUST00000085133.6
Atp2c1
ATPase, Ca++-sequestering
chr1_-_9298499 0.06 ENSMUST00000132064.1
Sntg1
syntrophin, gamma 1
chr7_+_28277706 0.06 ENSMUST00000094651.2
Eid2b
EP300 interacting inhibitor of differentiation 2B
chr19_-_6543019 0.03 ENSMUST00000113451.1
Slc22a12
solute carrier family 22 (organic anion/cation transporter), member 12
chr11_+_72689997 0.02 ENSMUST00000155998.1
Ankfy1
ankyrin repeat and FYVE domain containing 1
chr8_-_41041828 0.02 ENSMUST00000051379.7
Mtus1
mitochondrial tumor suppressor 1
chr2_-_79908389 0.02 ENSMUST00000090756.4
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr10_-_69352886 0.02 ENSMUST00000119827.1
ENSMUST00000020099.5
Cdk1
cyclin-dependent kinase 1
chr2_-_84650676 0.01 ENSMUST00000067232.3
Ctnnd1
catenin (cadherin associated protein), delta 1
chr3_+_141465592 0.01 ENSMUST00000130636.1
Unc5c
unc-5 homolog C (C. elegans)
chr3_+_55461758 0.00 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr2_+_178193075 0.00 ENSMUST00000103065.1
Phactr3
phosphatase and actin regulator 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou3f2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0033189 response to vitamin A(GO:0033189)
0.6 4.0 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.4 3.6 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.4 1.7 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.3 1.0 GO:0010710 regulation of collagen catabolic process(GO:0010710) negative regulation of extracellular matrix disassembly(GO:0010716)
0.3 1.7 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.3 2.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 0.6 GO:0046832 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.2 0.6 GO:1902226 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.2 0.9 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.6 GO:0015825 L-serine transport(GO:0015825)
0.1 0.4 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.1 0.4 GO:1904023 regulation of fermentation(GO:0043465) regulation of bone mineralization involved in bone maturation(GO:1900157) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023)
0.1 1.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 1.5 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 0.4 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 4.2 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 0.3 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.7 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 1.1 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.1 0.3 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.9 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.6 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 1.2 GO:0015809 arginine transport(GO:0015809)
0.1 0.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 8.7 GO:0007586 digestion(GO:0007586)
0.0 0.3 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.7 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0038190 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190)
0.0 0.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.6 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.8 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.5 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 2.0 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.9 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.8 GO:0006825 copper ion transport(GO:0006825)
0.0 1.6 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.6 GO:0043486 histone exchange(GO:0043486)
0.0 0.1 GO:0032468 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.0 0.4 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.8 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.3 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.7 GO:0016572 histone phosphorylation(GO:0016572)
0.0 1.1 GO:0043113 receptor clustering(GO:0043113)
0.0 0.5 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.4 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 0.1 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.1 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0071438 invadopodium membrane(GO:0071438)
0.1 2.0 GO:0042581 specific granule(GO:0042581)
0.1 0.4 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.7 GO:0031673 H zone(GO:0031673)
0.1 0.6 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 0.7 GO:0001940 male pronucleus(GO:0001940)
0.1 0.9 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.7 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.8 GO:0044754 autolysosome(GO:0044754)
0.0 0.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.5 GO:0060091 kinocilium(GO:0060091)
0.0 1.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0099522 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.4 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 2.4 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 21.5 GO:0005615 extracellular space(GO:0005615)
0.0 1.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.5 GO:0043034 costamere(GO:0043034)
0.0 1.2 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0004962 endothelin receptor activity(GO:0004962)
0.3 1.7 GO:0043532 angiostatin binding(GO:0043532)
0.3 2.2 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.3 0.9 GO:0042936 dipeptide transporter activity(GO:0042936)
0.2 0.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2 1.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 1.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.3 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 1.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.3 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 0.9 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.1 0.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 3.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 6.4 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 9.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.3 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0070401 NADP+ binding(GO:0070401)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 2.7 GO:0042562 hormone binding(GO:0042562)
0.0 1.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.1 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.7 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 3.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 2.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.9 PID AURORA A PATHWAY Aurora A signaling
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.0 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 3.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 2.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors