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GSE58827: Dynamics of the Mouse Liver

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Results for Pou5f1

Z-value: 0.80

Motif logo

Transcription factors associated with Pou5f1

Gene Symbol Gene ID Gene Info
ENSMUSG00000024406.10 POU domain, class 5, transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou5f1mm10_v2_chr17_+_35506018_355060490.076.7e-01Click!

Activity profile of Pou5f1 motif

Sorted Z-values of Pou5f1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_69605829 2.25 ENSMUST00000047889.6
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr14_-_20269162 1.88 ENSMUST00000024155.7
potassium channel, subfamily K, member 16
chr7_+_110773658 1.71 ENSMUST00000143786.1
adenosine monophosphate deaminase 3
chr10_+_75948292 1.66 ENSMUST00000000926.2
pre-B lymphocyte gene 3
chr7_+_110774240 1.65 ENSMUST00000147587.1
adenosine monophosphate deaminase 3
chr10_+_127000709 1.57 ENSMUST00000026500.5
ENSMUST00000142698.1
advillin
chr12_-_114416895 1.53 ENSMUST00000179796.1
immunoglobulin heavy variable V6-5
chr5_+_76840597 1.37 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
RIKEN cDNA C530008M17 gene
chr6_-_83536215 1.35 ENSMUST00000075161.5
actin, gamma 2, smooth muscle, enteric
chr6_-_69400097 1.33 ENSMUST00000177795.1
immunoglobulin kappa variable 4-62
chr8_-_122678653 1.32 ENSMUST00000134045.1
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr4_-_64046925 1.23 ENSMUST00000107377.3
tenascin C
chr3_+_130180882 1.23 ENSMUST00000106353.1
ENSMUST00000080335.4
collagen, type XXV, alpha 1
chr6_+_136518820 1.22 ENSMUST00000032335.6
activating transcription factor 7 interacting protein
chr11_-_3504766 1.16 ENSMUST00000044507.5
inositol polyphosphate 5-phosphatase J
chr17_-_35164891 1.11 ENSMUST00000025253.5
proline-rich coiled-coil 2A
chr11_-_116077927 1.06 ENSMUST00000156545.1
unc-13 homolog D (C. elegans)
chr11_-_106314494 1.05 ENSMUST00000167143.1
CD79B antigen
chr13_+_21722057 1.05 ENSMUST00000110476.3
histone cluster 1, H2bm
chr17_+_40811089 1.04 ENSMUST00000024721.7
Rhesus blood group-associated A glycoprotein
chr6_-_69243445 1.04 ENSMUST00000101325.3
immunoglobulin kappa chain variable 4-71
chr11_+_44617310 1.03 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
early B cell factor 1
chr12_-_115790884 0.99 ENSMUST00000081809.5
immunoglobulin heavy variable 1-73
chr2_-_33087169 0.99 ENSMUST00000102810.3
GTPase activating RANGAP domain-like 3
chr17_+_28207778 0.97 ENSMUST00000002327.5
differentially expressed in FDCP 6
chr6_-_92481343 0.96 ENSMUST00000113445.1
prickle homolog 2 (Drosophila)
chr5_+_66676098 0.96 ENSMUST00000031131.9
ubiquitin carboxy-terminal hydrolase L1
chr6_+_145121727 0.96 ENSMUST00000032396.6
lymphoid-restricted membrane protein
chr9_-_95815389 0.94 ENSMUST00000119760.1
plastin 1 (I-isoform)
chr18_+_50051702 0.93 ENSMUST00000134348.1
ENSMUST00000153873.2
tumor necrosis factor, alpha-induced protein 8
chr1_-_45503282 0.93 ENSMUST00000086430.4
collagen, type V, alpha 2
chr3_+_96269695 0.92 ENSMUST00000051089.3
ENSMUST00000177113.1
histone cluster 2, H2bb
chr9_+_106222598 0.91 ENSMUST00000062241.9
toll-like receptor 9
chr11_+_57011798 0.91 ENSMUST00000036315.9
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr5_+_13399309 0.91 ENSMUST00000030714.7
ENSMUST00000141968.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr18_+_65582239 0.90 ENSMUST00000182684.1
zinc finger protein 532
chr16_-_92697315 0.89 ENSMUST00000168195.1
ENSMUST00000113956.3
runt related transcription factor 1
chr1_-_132390301 0.89 ENSMUST00000132435.1
transmembrane and coiled-coil domains 2
chrX_+_93675088 0.89 ENSMUST00000045898.3
phosphate cytidylyltransferase 1, choline, beta isoform
chr4_-_152477433 0.87 ENSMUST00000159186.1
ENSMUST00000162017.1
ENSMUST00000030768.2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr11_+_83850832 0.87 ENSMUST00000021016.3
HNF1 homeobox B
chr7_+_82174796 0.85 ENSMUST00000032874.7
SH3-domain GRB2-like 3
chr13_+_37825975 0.85 ENSMUST00000138043.1
ras responsive element binding protein 1
chr11_+_57011945 0.85 ENSMUST00000094179.4
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr14_+_70890099 0.83 ENSMUST00000022699.8
glial cell line derived neurotrophic factor family receptor alpha 2
chr12_-_36042476 0.83 ENSMUST00000020896.8
tetraspanin 13
chr9_-_51328898 0.82 ENSMUST00000039959.4
RIKEN cDNA 1810046K07 gene
chr2_+_124610573 0.81 ENSMUST00000103239.3
ENSMUST00000103240.2
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr10_+_79927330 0.81 ENSMUST00000105376.1
AT rich interactive domain 3A (BRIGHT-like)
chr1_+_87470258 0.80 ENSMUST00000027476.4
RIKEN cDNA 3110079O15 gene
chr13_-_28953690 0.80 ENSMUST00000067230.5
SRY-box containing gene 4
chr10_+_79927039 0.80 ENSMUST00000019708.5
ENSMUST00000105377.1
AT rich interactive domain 3A (BRIGHT-like)
chr11_+_95337012 0.79 ENSMUST00000037502.6
family with sequence similarity 117, member A
chr19_+_53460610 0.79 ENSMUST00000180442.1
RIKEN cDNA 4833407H14 gene
chr17_+_27057288 0.79 ENSMUST00000049308.8
inositol 1,4,5-triphosphate receptor 3
chr15_-_66831625 0.77 ENSMUST00000164163.1
src-like adaptor
chr11_+_83850863 0.77 ENSMUST00000108114.2
HNF1 homeobox B
chr17_+_47140942 0.75 ENSMUST00000077951.7
transcriptional regulating factor 1
chr8_+_68880491 0.75 ENSMUST00000015712.8
lipoprotein lipase
chr7_+_28982832 0.74 ENSMUST00000085835.6
mitogen-activated protein kinase kinase kinase kinase 1
chr9_+_86743641 0.74 ENSMUST00000179574.1
protease, serine, 35
chr10_-_127620960 0.74 ENSMUST00000121829.1
low density lipoprotein receptor-related protein 1
chr10_-_127620922 0.73 ENSMUST00000118455.1
low density lipoprotein receptor-related protein 1
chr12_+_38780284 0.73 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
ets variant gene 1
chr12_-_46818749 0.73 ENSMUST00000021438.6
neuro-oncological ventral antigen 1
chr8_-_87959560 0.73 ENSMUST00000109655.2
zinc finger protein 423
chr12_+_89812467 0.72 ENSMUST00000110133.2
ENSMUST00000110130.2
neurexin III
chr15_-_100599864 0.72 ENSMUST00000177247.2
ENSMUST00000177505.2
POU domain, class 6, transcription factor 1
chr2_-_170194033 0.72 ENSMUST00000180625.1
predicted gene, 17619
chr6_-_148946146 0.72 ENSMUST00000132696.1
family with sequence similarity 60, member A
chr5_+_66968961 0.71 ENSMUST00000132991.1
LIM and calponin homology domains 1
chr9_+_86743616 0.70 ENSMUST00000036426.6
protease, serine, 35
chr10_+_42860776 0.69 ENSMUST00000105494.1
sex comb on midleg-like 4 (Drosophila)
chr9_-_70421533 0.68 ENSMUST00000034742.6
cyclin B2
chr5_-_122989086 0.68 ENSMUST00000046073.9
lysine (K)-specific demethylase 2B
chr1_+_91540553 0.68 ENSMUST00000027538.7
ankyrin repeat and SOCS box-containing 1
chr13_+_97241096 0.67 ENSMUST00000041623.7
ectodermal-neural cortex 1
chr9_+_35423582 0.65 ENSMUST00000154652.1
cell adhesion molecule-related/down-regulated by oncogenes
chr1_-_168431502 0.65 ENSMUST00000064438.4
pre B cell leukemia homeobox 1
chr1_-_91459254 0.65 ENSMUST00000069620.8
period circadian clock 2
chr3_+_83766300 0.64 ENSMUST00000029625.7
secreted frizzled-related protein 2
chr7_-_102100227 0.64 ENSMUST00000106937.1
ADP-ribosyltransferase 5
chr6_-_69284319 0.63 ENSMUST00000103349.1
immunoglobulin kappa variable 4-69
chr7_-_120982260 0.63 ENSMUST00000033169.8
cerebellar degeneration-related 2
chr8_-_90908415 0.63 ENSMUST00000098517.1
predicted gene 6658
chr5_-_141000590 0.63 ENSMUST00000085786.5
caspase recruitment domain family, member 11
chr17_-_28486082 0.62 ENSMUST00000079413.3
FK506 binding protein 5
chr5_-_122988533 0.61 ENSMUST00000086200.4
ENSMUST00000156474.1
lysine (K)-specific demethylase 2B
chr4_-_128806045 0.61 ENSMUST00000106072.2
ENSMUST00000170934.1
zinc finger protein 362
chr5_+_21543525 0.61 ENSMUST00000035651.4
leucine rich repeat containing 17
chr9_-_71896047 0.60 ENSMUST00000184448.1
transcription factor 12
chr2_+_143546144 0.60 ENSMUST00000028905.9
proprotein convertase subtilisin/kexin type 2
chr8_+_70234613 0.59 ENSMUST00000145078.1
SURP and G patch domain containing 2
chr18_-_43393346 0.59 ENSMUST00000025379.7
dihydropyrimidinase-like 3
chr6_-_67037399 0.59 ENSMUST00000043098.6
growth arrest and DNA-damage-inducible 45 alpha
chr3_+_122044428 0.59 ENSMUST00000013995.8
ATP-binding cassette, sub-family A (ABC1), member 4
chr4_+_97772734 0.58 ENSMUST00000152023.1
nuclear factor I/A
chr13_+_37826018 0.58 ENSMUST00000110238.2
ras responsive element binding protein 1
chr10_+_85386813 0.57 ENSMUST00000105307.1
ENSMUST00000020231.3
BTB (POZ) domain containing 11
chr17_-_35516780 0.56 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
transcription factor 19
chr18_+_65582390 0.55 ENSMUST00000169679.1
ENSMUST00000183326.1
zinc finger protein 532
chr13_-_41358990 0.54 ENSMUST00000163623.1
neural precursor cell expressed, developmentally down-regulated gene 9
chr2_+_72476225 0.54 ENSMUST00000157019.1
cell division cycle associated 7
chr11_-_116077562 0.54 ENSMUST00000174822.1
unc-13 homolog D (C. elegans)
chr1_+_12718496 0.54 ENSMUST00000088585.3
sulfatase 1
chr2_+_72476159 0.53 ENSMUST00000102691.4
cell division cycle associated 7
chrX_-_57338598 0.52 ENSMUST00000033468.4
ENSMUST00000114736.1
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr12_-_101819048 0.52 ENSMUST00000021603.8
fibulin 5
chr11_-_116077954 0.51 ENSMUST00000106451.1
ENSMUST00000075036.2
unc-13 homolog D (C. elegans)
chr17_+_28142267 0.51 ENSMUST00000043503.3
signal peptide, CUB domain, EGF-like 3
chr16_+_17233560 0.51 ENSMUST00000090190.5
ENSMUST00000115698.2
hypermethylated in cancer 2
chr11_-_30198232 0.51 ENSMUST00000102838.3
spectrin beta, non-erythrocytic 1
chr7_+_91090728 0.51 ENSMUST00000074273.3
discs, large homolog 2 (Drosophila)
chr4_+_108479081 0.51 ENSMUST00000155068.1
zinc finger, CCHC domain containing 11
chr7_-_28372597 0.51 ENSMUST00000144700.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr5_-_5265224 0.50 ENSMUST00000115450.1
cyclin-dependent kinase 14
chr16_+_91729281 0.50 ENSMUST00000114001.1
ENSMUST00000113999.1
ENSMUST00000064797.5
ENSMUST00000114002.2
ENSMUST00000095909.3
ENSMUST00000056482.7
ENSMUST00000113996.1
intersectin 1 (SH3 domain protein 1A)
chr11_-_116077606 0.49 ENSMUST00000106450.1
unc-13 homolog D (C. elegans)
chr12_-_114406773 0.48 ENSMUST00000177949.1
immunoglobulin heavy variable V6-4
chr6_-_29216277 0.48 ENSMUST00000162215.1
inosine 5'-phosphate dehydrogenase 1
chr13_+_22043189 0.48 ENSMUST00000110452.1
histone cluster 1, H2bj
chr6_-_52226165 0.48 ENSMUST00000114425.2
homeobox A9
chr2_-_152398046 0.48 ENSMUST00000063332.8
ENSMUST00000182625.1
SRY-box containing gene 12
chr13_+_23746734 0.47 ENSMUST00000099703.2
histone cluster 1, H2bb
chr7_+_91090697 0.47 ENSMUST00000107196.2
discs, large homolog 2 (Drosophila)
chr11_+_108920800 0.47 ENSMUST00000140821.1
axin2
chr17_+_27556641 0.47 ENSMUST00000119486.1
ENSMUST00000118599.1
high mobility group AT-hook 1
chr9_-_102354685 0.47 ENSMUST00000035129.7
ENSMUST00000085169.5
Eph receptor B1
chr5_-_115652974 0.47 ENSMUST00000121746.1
ENSMUST00000118576.1
coiled-coil domain containing 64
chr13_+_5861489 0.46 ENSMUST00000000080.6
Kruppel-like factor 6
chrX_+_166344692 0.46 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
glycoprotein m6b
chr8_+_22808275 0.45 ENSMUST00000068068.4
RIKEN cDNA 1700041G16 gene
chr4_-_133967235 0.45 ENSMUST00000123234.1
high mobility group nucleosomal binding domain 2
chr18_+_37484955 0.45 ENSMUST00000053856.4
protocadherin beta 17
chr3_-_50443603 0.45 ENSMUST00000029297.4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chrX_-_164250368 0.44 ENSMUST00000112263.1
BMX non-receptor tyrosine kinase
chr6_-_13839916 0.44 ENSMUST00000060442.7
G protein-coupled receptor 85
chr10_-_79908891 0.44 ENSMUST00000165684.1
ENSMUST00000164705.1
ENSMUST00000105378.2
ENSMUST00000170409.1
mediator complex subunit 16
chr4_-_140810646 0.44 ENSMUST00000026377.2
peptidyl arginine deiminase, type III
chr16_+_17144600 0.43 ENSMUST00000115702.1
YdjC homolog (bacterial)
chr13_-_54688246 0.43 ENSMUST00000122935.1
ENSMUST00000128257.1
ring finger protein 44
chr2_+_91096744 0.43 ENSMUST00000132741.2
spleen focus forming virus (SFFV) proviral integration oncogene
chr3_-_144819494 0.43 ENSMUST00000029929.7
chloride channel calcium activated 2
chr1_-_126830786 0.42 ENSMUST00000162646.1
NCK-associated protein 5
chr5_-_123865491 0.42 ENSMUST00000057145.5
niacin receptor 1
chr8_+_120488416 0.42 ENSMUST00000034279.9
genetic suppressor element 1
chr3_-_97227364 0.41 ENSMUST00000046521.7
B cell CLL/lymphoma 9
chr13_-_22042949 0.41 ENSMUST00000091741.4
histone cluster 1, H2ag
chr18_-_42899470 0.40 ENSMUST00000120632.1
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr6_+_92092369 0.40 ENSMUST00000113463.1
nuclear receptor subfamily 2, group C, member 2
chr6_-_3498297 0.40 ENSMUST00000183736.1
HEPACAM family member 2
chr8_+_118283719 0.40 ENSMUST00000117160.1
cadherin 13
chr5_+_137629169 0.39 ENSMUST00000176667.1
leucine-rich repeats and calponin homology (CH) domain containing 4
chr7_-_102477902 0.39 ENSMUST00000061482.5
olfactory receptor 543
chr13_-_54688264 0.39 ENSMUST00000150626.1
ENSMUST00000134177.1
ring finger protein 44
chr13_+_102693522 0.38 ENSMUST00000022124.3
ENSMUST00000171267.1
ENSMUST00000167144.1
ENSMUST00000170878.1
CD180 antigen
chr8_+_70234187 0.38 ENSMUST00000164403.1
ENSMUST00000093458.4
SURP and G patch domain containing 2
chr16_-_22439570 0.38 ENSMUST00000170393.1
ets variant gene 5
chr8_-_89147247 0.38 ENSMUST00000177870.1
predicted gene 6625
chr7_-_28372494 0.38 ENSMUST00000119990.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr17_+_27556668 0.37 ENSMUST00000117254.1
ENSMUST00000118570.1
high mobility group AT-hook 1
chr2_+_121289589 0.37 ENSMUST00000094639.3
microtubule-associated protein 1 A
chr2_+_25180737 0.37 ENSMUST00000104999.2
Notch-regulated ankyrin repeat protein
chr7_-_45052865 0.37 ENSMUST00000057293.6
proline rich 12
chr16_-_91728701 0.36 ENSMUST00000114023.2
ENSMUST00000117644.1
crystallin, zeta (quinone reductase)-like 1
chr9_-_54661870 0.36 ENSMUST00000034822.5
acyl-CoA synthetase bubblegum family member 1
chr3_-_61365951 0.35 ENSMUST00000066298.2
RIKEN cDNA B430305J03 gene
chr17_+_27556613 0.35 ENSMUST00000117600.1
ENSMUST00000114888.3
high mobility group AT-hook 1
chr13_+_42680565 0.35 ENSMUST00000128646.1
phosphatase and actin regulator 1
chr4_+_123183722 0.35 ENSMUST00000152194.1
hippocalcin-like 4
chr5_+_92897981 0.35 ENSMUST00000113051.2
shroom family member 3
chr2_+_30595037 0.35 ENSMUST00000102853.3
CSA-conditional, T cell activation-dependent protein
chr19_+_8941865 0.34 ENSMUST00000096240.2
metastasis-associated gene family, member 2
chr1_-_184732444 0.34 ENSMUST00000174257.1
H2.0-like homeobox
chr11_+_51289920 0.34 ENSMUST00000102765.2
collagen, type XXIII, alpha 1
chr6_-_55681257 0.34 ENSMUST00000044767.8
neurogenic differentiation 6
chr12_-_34528844 0.33 ENSMUST00000110819.2
histone deacetylase 9
chr13_+_37826225 0.33 ENSMUST00000128570.1
ras responsive element binding protein 1
chr3_-_102782708 0.33 ENSMUST00000029450.3
ENSMUST00000172026.1
ENSMUST00000170856.1
thyroid stimulating hormone, beta subunit
chr4_-_62360524 0.33 ENSMUST00000107461.1
ENSMUST00000084528.3
FK506 binding protein 15
chr1_+_52008210 0.33 ENSMUST00000027277.5
signal transducer and activator of transcription 4
chr4_-_152128858 0.33 ENSMUST00000049305.7
espin
chr10_+_97479470 0.33 ENSMUST00000105287.3
decorin
chr13_+_40917626 0.32 ENSMUST00000067778.6
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr5_-_74065736 0.32 ENSMUST00000145016.1
ubiquitin specific peptidase 46
chr3_-_87263703 0.32 ENSMUST00000146512.1
Fc receptor-like S, scavenger receptor
chr11_+_98741805 0.32 ENSMUST00000064187.5
thyroid hormone receptor alpha
chr3_+_92316705 0.32 ENSMUST00000061038.2
small proline-rich protein 2B
chr1_-_126830632 0.32 ENSMUST00000112583.1
ENSMUST00000094609.3
NCK-associated protein 5
chr11_+_98741871 0.32 ENSMUST00000103139.4
thyroid hormone receptor alpha
chr2_+_28192971 0.32 ENSMUST00000113920.1
olfactomedin 1
chr9_-_85327110 0.31 ENSMUST00000034802.8
family with sequence similarity 46, member A
chr4_-_43562397 0.31 ENSMUST00000030187.7
talin 1
chr4_+_150997081 0.31 ENSMUST00000030803.1
urotensin 2
chr3_-_87263518 0.31 ENSMUST00000090986.4
Fc receptor-like S, scavenger receptor
chr5_+_66968559 0.30 ENSMUST00000127184.1
LIM and calponin homology domains 1
chr12_+_29528382 0.30 ENSMUST00000049784.9
myelin transcription factor 1-like
chr10_+_115817247 0.30 ENSMUST00000035563.7
ENSMUST00000080630.3
ENSMUST00000179196.1
tetraspanin 8
chr18_+_52767994 0.30 ENSMUST00000025413.7
ENSMUST00000163742.2
ENSMUST00000178011.1
synuclein, alpha interacting protein (synphilin)
chr5_+_137630116 0.30 ENSMUST00000175968.1
leucine-rich repeats and calponin homology (CH) domain containing 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou5f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.4 1.6 GO:0061228 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.4 1.6 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.4 3.4 GO:0032264 IMP salvage(GO:0032264)
0.3 1.0 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.3 1.2 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.3 2.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.3 0.9 GO:0032741 positive regulation of interleukin-18 production(GO:0032741) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.3 0.9 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.3 2.6 GO:0002432 granuloma formation(GO:0002432)
0.3 1.3 GO:0021993 initiation of neural tube closure(GO:0021993)
0.3 1.8 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2 0.9 GO:1902896 terminal web assembly(GO:1902896)
0.2 1.1 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.2 0.6 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.2 0.6 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2 0.6 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.2 0.8 GO:0035910 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.2 1.0 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.2 0.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 1.7 GO:0051025 negative regulation of immunoglobulin secretion(GO:0051025)
0.2 1.0 GO:0007412 axon target recognition(GO:0007412)
0.2 0.5 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.6 GO:0030070 insulin processing(GO:0030070)
0.1 0.3 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1 1.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.8 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 1.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.3 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 1.1 GO:0070970 interleukin-2 secretion(GO:0070970)
0.1 0.4 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.3 GO:0021660 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.1 0.4 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 3.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.5 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.7 GO:0048539 bone marrow development(GO:0048539)
0.1 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.3 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.1 0.5 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.9 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.9 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.5 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.1 1.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.2 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 1.0 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.1 0.7 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.2 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 1.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.5 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.1 0.5 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.8 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.2 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.2 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.3 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0002194 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.3 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.4 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) germline stem cell asymmetric division(GO:0098728)
0.0 0.3 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.8 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.2 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.0 0.6 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.7 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 1.5 GO:0007616 long-term memory(GO:0007616)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:1990743 protein sialylation(GO:1990743)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 1.0 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.1 GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.0 0.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.3 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.3 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0008343 adult feeding behavior(GO:0008343) behavioral response to ethanol(GO:0048149) positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 1.4 GO:0051693 actin filament capping(GO:0051693)
0.0 0.2 GO:0045346 regulation of MHC class II biosynthetic process(GO:0045346)
0.0 0.3 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.4 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.8 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.3 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 1.2 GO:0006284 base-excision repair(GO:0006284)
0.0 0.0 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0 1.0 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 1.0 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0 0.2 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 2.5 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.0 GO:0060853 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.0 GO:0045608 coronary vein morphogenesis(GO:0003169) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of cell adhesion involved in heart morphogenesis(GO:0061344) positive regulation of ephrin receptor signaling pathway(GO:1901189)
0.0 0.5 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.7 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.3 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.9 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.4 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.4 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.7 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.4 GO:0031111 negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 2.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.8 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.0 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 0.3 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.2 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.2 GO:0042756 drinking behavior(GO:0042756)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005588 collagen type V trimer(GO:0005588)
0.3 1.8 GO:0044308 axonal spine(GO:0044308)
0.2 2.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 2.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 0.9 GO:0036019 endolysosome(GO:0036019)
0.2 4.1 GO:0019814 immunoglobulin complex(GO:0019814)
0.2 0.5 GO:0070877 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.1 1.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.5 GO:0071953 elastic fiber(GO:0071953)
0.1 0.9 GO:1990357 terminal web(GO:1990357)
0.1 0.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 1.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.5 GO:0032437 cuticular plate(GO:0032437)
0.0 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.7 GO:0042627 chylomicron(GO:0042627)
0.0 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 2.1 GO:0005581 collagen trimer(GO:0005581)
0.0 2.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 1.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.4 1.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.4 3.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 1.8 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.3 0.8 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.2 1.0 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.2 0.9 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 0.6 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.2 2.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 0.9 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 2.9 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.2 1.2 GO:0045545 syndecan binding(GO:0045545)
0.1 0.5 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.9 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 3.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 1.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.5 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.3 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.1 0.5 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 1.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.4 GO:0055100 adiponectin binding(GO:0055100)
0.1 1.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.4 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.4 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.2 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 0.6 GO:0050700 CARD domain binding(GO:0050700)
0.0 1.0 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 1.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 0.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0019002 GMP binding(GO:0019002)
0.0 0.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.2 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 1.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.0 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 2.4 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.9 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.7 PID ATR PATHWAY ATR signaling pathway
0.0 0.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 2.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID ERBB4 PATHWAY ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 1.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 0.9 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 0.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 1.6 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 0.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.0 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.6 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.7 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains