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GSE58827: Dynamics of the Mouse Liver
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Results for Ppard
Z-value: 0.54
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Transcription factors associated with Ppard
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Ppard | mm10_v2_chr17_+_28272191_28272205 | -0.17 | 3.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr17_-_46438471 Show fit | 5.85 |
ENSMUST00000087012.5
|
solute carrier family 22 (organic anion transporter), member 7 |
|
| chr9_-_46235260 Show fit | 2.83 |
ENSMUST00000121916.1
ENSMUST00000034586.2 |
apolipoprotein C-III |
|
| chr3_-_79628660 Show fit | 1.81 |
ENSMUST00000120992.1
|
electron transferring flavoprotein, dehydrogenase |
|
| chr9_-_46235631 Show fit | 1.78 |
ENSMUST00000118649.1
|
apolipoprotein C-III |
|
| chr16_+_22951072 Show fit | 1.75 |
ENSMUST00000023590.8
|
histidine-rich glycoprotein |
|
| chr9_+_108662098 Show fit | 1.40 |
ENSMUST00000035222.5
|
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 |
|
| chr3_-_79628859 Show fit | 1.35 |
ENSMUST00000029386.7
|
electron transferring flavoprotein, dehydrogenase |
|
| chr9_-_22002599 Show fit | 1.32 |
ENSMUST00000115336.2
ENSMUST00000044926.5 |
coiled-coil domain containing 151 |
|
| chr9_+_107340593 Show fit | 1.24 |
ENSMUST00000042581.2
|
RIKEN cDNA 6430571L13 gene |
|
| chr10_-_125328957 Show fit | 1.18 |
ENSMUST00000063318.2
|
solute carrier family 16 (monocarboxylic acid transporters), member 7 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Ppard
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.9 | GO:0035634 | response to stilbenoid(GO:0035634) |
| 0.2 | 5.1 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 1.2 | 4.6 | GO:0010982 | regulation of high-density lipoprotein particle clearance(GO:0010982) |
| 0.4 | 2.3 | GO:0006083 | acetate metabolic process(GO:0006083) |
| 0.6 | 1.8 | GO:0034395 | regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) |
| 0.1 | 1.4 | GO:0015879 | carnitine transport(GO:0015879) |
| 0.1 | 1.3 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.3 | 1.2 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
| 0.0 | 1.2 | GO:0060351 | cartilage development involved in endochondral bone morphogenesis(GO:0060351) |
| 0.4 | 1.1 | GO:0042450 | arginine biosynthetic process via ornithine(GO:0042450) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 4.6 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 1.0 | 4.0 | GO:0045251 | mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251) |
| 0.0 | 2.3 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.6 | 1.8 | GO:0032010 | phagolysosome(GO:0032010) |
| 0.1 | 1.8 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
| 0.0 | 1.3 | GO:0005814 | centriole(GO:0005814) |
| 0.1 | 0.9 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.0 | 0.8 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.6 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.0 | 0.4 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.9 | GO:0005452 | inorganic anion exchanger activity(GO:0005452) |
| 1.3 | 5.0 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 0.6 | 3.2 | GO:0016649 | electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649) |
| 0.8 | 2.3 | GO:0019807 | aspartoacylase activity(GO:0019807) |
| 0.2 | 1.4 | GO:0015199 | amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) |
| 0.3 | 1.2 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 0.3 | 1.1 | GO:0016743 | carboxyl- or carbamoyltransferase activity(GO:0016743) |
| 0.2 | 1.1 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.0 | 1.1 | GO:0009055 | electron carrier activity(GO:0009055) |
| 0.0 | 1.1 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 1.1 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 5.9 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.2 | 4.6 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.1 | 4.2 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 2.2 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 1.8 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 1.2 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 1.0 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.1 | 0.9 | REACTOME LIPOPROTEIN METABOLISM | Genes involved in Lipoprotein metabolism |
| 0.1 | 0.9 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 0.9 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |