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GSE58827: Dynamics of the Mouse Liver

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Results for Ptf1a

Z-value: 1.45

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Transcription factors associated with Ptf1a

Gene Symbol Gene ID Gene Info
Ptf1a
ENSMUSG00000026735.2 pancreas specific transcription factor, 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ptf1amm10_v2_chr2_+_19445632_194456630.782.7e-08Click!

Activity profile of Ptf1a motif

Sorted Z-values of Ptf1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_41314700 29.30 ENSMUST00000064324.5
Try5
trypsin 5
chr6_+_41458923 22.61 ENSMUST00000031910.7
Prss1
protease, serine, 1 (trypsin 1)
chr6_+_41392356 22.34 ENSMUST00000049079.7
Gm5771
predicted gene 5771
chr7_+_28540863 18.76 ENSMUST00000119180.2
Sycn
syncollin
chr6_+_41354105 18.51 ENSMUST00000072103.5
Try10
trypsin 10
chr6_+_41302265 16.94 ENSMUST00000031913.4
Try4
trypsin 4
chr7_-_131322292 15.52 ENSMUST00000046611.7
Cuzd1
CUB and zona pellucida-like domains 1
chr2_+_173153048 7.25 ENSMUST00000029017.5
Pck1
phosphoenolpyruvate carboxykinase 1, cytosolic
chr6_-_69243445 6.43 ENSMUST00000101325.3
Igkv4-71
immunoglobulin kappa chain variable 4-71
chr1_-_90153396 3.53 ENSMUST00000113094.2
Iqca
IQ motif containing with AAA domain
chr10_+_95417352 3.53 ENSMUST00000181781.1
5730420D15Rik
RIKEN cDNA 5730420D15 gene
chr14_-_63417125 3.36 ENSMUST00000014597.3
Blk
B lymphoid kinase
chr11_+_101330605 3.03 ENSMUST00000103105.3
Aoc3
amine oxidase, copper containing 3
chr8_+_105048592 2.91 ENSMUST00000093222.5
ENSMUST00000093223.3
Ces3a
carboxylesterase 3A
chrX_+_160390684 2.64 ENSMUST00000112408.2
ENSMUST00000112402.1
ENSMUST00000112401.1
ENSMUST00000112400.1
ENSMUST00000112405.2
ENSMUST00000112404.2
ENSMUST00000146805.1
Gpr64
G protein-coupled receptor 64
chrX_-_162964557 2.07 ENSMUST00000038769.2
S100g
S100 calcium binding protein G
chr7_-_3249711 1.92 ENSMUST00000108653.2
Nlrp12
NLR family, pyrin domain containing 12
chr15_-_77399086 1.74 ENSMUST00000175919.1
ENSMUST00000176074.1
Apol7a
apolipoprotein L 7a
chr14_-_33185489 1.72 ENSMUST00000159606.1
Wdfy4
WD repeat and FYVE domain containing 4
chr11_+_120633719 1.67 ENSMUST00000181502.1
Gm17586
predicted gene, 17586
chr3_+_138277489 1.54 ENSMUST00000004232.9
Adh1
alcohol dehydrogenase 1 (class I)
chr11_+_4031770 1.51 ENSMUST00000019512.7
Sec14l4
SEC14-like 4 (S. cerevisiae)
chr11_-_99155067 1.40 ENSMUST00000103134.3
Ccr7
chemokine (C-C motif) receptor 7
chr10_-_95417099 1.36 ENSMUST00000135822.1
Socs2
suppressor of cytokine signaling 2
chr2_+_164948219 1.35 ENSMUST00000017881.2
Mmp9
matrix metallopeptidase 9
chr16_+_91269759 1.24 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr7_-_30944017 1.20 ENSMUST00000062620.7
Hamp
hepcidin antimicrobial peptide
chr7_-_140102367 1.14 ENSMUST00000142105.1
Fuom
fucose mutarotase
chr2_+_11705712 1.03 ENSMUST00000138856.1
ENSMUST00000078834.5
ENSMUST00000114834.3
ENSMUST00000114833.3
ENSMUST00000114831.2
ENSMUST00000114832.2
Il15ra
interleukin 15 receptor, alpha chain
chr10_-_77089428 1.01 ENSMUST00000156009.1
Col18a1
collagen, type XVIII, alpha 1
chr2_-_148038270 1.00 ENSMUST00000132070.1
9030622O22Rik
RIKEN cDNA 9030622O22 gene
chr14_-_55944536 0.97 ENSMUST00000022834.6
Cma1
chymase 1, mast cell
chr11_-_90390895 0.92 ENSMUST00000004051.7
Hlf
hepatic leukemia factor
chr11_+_78465697 0.87 ENSMUST00000001126.3
Slc46a1
solute carrier family 46, member 1
chr14_+_52792208 0.85 ENSMUST00000178426.2
Trav9d-1
T cell receptor alpha variable 9D-1
chr17_-_28517509 0.85 ENSMUST00000114792.1
ENSMUST00000177939.1
Fkbp5
FK506 binding protein 5
chr11_-_6444352 0.84 ENSMUST00000093346.5
ENSMUST00000109737.2
H2afv
H2A histone family, member V
chr14_-_70207637 0.84 ENSMUST00000022682.5
Sorbs3
sorbin and SH3 domain containing 3
chr6_-_136781718 0.83 ENSMUST00000078095.6
ENSMUST00000032338.7
Gucy2c
guanylate cyclase 2c
chr10_+_127048235 0.82 ENSMUST00000165764.1
Cyp27b1
cytochrome P450, family 27, subfamily b, polypeptide 1
chr5_-_120887582 0.82 ENSMUST00000086368.5
Oas1g
2'-5' oligoadenylate synthetase 1G
chr5_-_99252839 0.77 ENSMUST00000168092.1
ENSMUST00000031276.8
Rasgef1b
RasGEF domain family, member 1B
chr2_-_30415302 0.77 ENSMUST00000132981.2
ENSMUST00000129494.1
Crat
carnitine acetyltransferase
chr10_-_75932468 0.72 ENSMUST00000120281.1
ENSMUST00000000924.6
Mmp11
matrix metallopeptidase 11
chr9_-_106476590 0.68 ENSMUST00000112479.2
Parp3
poly (ADP-ribose) polymerase family, member 3
chr4_-_155010984 0.66 ENSMUST00000105631.2
ENSMUST00000139976.2
ENSMUST00000145662.2
Plch2
phospholipase C, eta 2
chr7_+_104329471 0.63 ENSMUST00000180136.1
ENSMUST00000178316.1
Trim34b
tripartite motif-containing 34B
chr15_+_31276491 0.61 ENSMUST00000068987.5
Fam136b-ps
family with sequence similarity 136, member B, pseudogene
chr9_-_108597558 0.59 ENSMUST00000006853.5
P4htm
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr19_+_7056731 0.56 ENSMUST00000040261.5
Macrod1
MACRO domain containing 1
chr7_+_118600152 0.55 ENSMUST00000121744.1
Tmc5
transmembrane channel-like gene family 5
chr11_+_66957894 0.54 ENSMUST00000127166.1
9130409J20Rik
RIKEN cDNA 9130409J20 gene
chr13_-_60864373 0.54 ENSMUST00000091569.5
4930486L24Rik
RIKEN cDNA 4930486L24 gene
chr5_-_31048014 0.53 ENSMUST00000137223.1
Slc5a6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
chr7_+_28756138 0.52 ENSMUST00000178767.1
Gm6537
predicted gene 6537
chr15_-_99087817 0.52 ENSMUST00000064462.3
C1ql4
complement component 1, q subcomponent-like 4
chr11_+_82911253 0.52 ENSMUST00000164945.1
ENSMUST00000018989.7
Unc45b
unc-45 homolog B (C. elegans)
chr7_-_13054514 0.51 ENSMUST00000182087.1
Mzf1
myeloid zinc finger 1
chr8_+_22283441 0.50 ENSMUST00000077194.1
Tpte
transmembrane phosphatase with tensin homology
chr4_+_155839675 0.47 ENSMUST00000141883.1
Mxra8
matrix-remodelling associated 8
chr4_-_64046925 0.46 ENSMUST00000107377.3
Tnc
tenascin C
chr1_+_20951666 0.43 ENSMUST00000038447.4
Efhc1
EF-hand domain (C-terminal) containing 1
chr11_-_118355496 0.42 ENSMUST00000017610.3
Timp2
tissue inhibitor of metalloproteinase 2
chr14_-_33185066 0.42 ENSMUST00000061753.8
ENSMUST00000130509.2
Wdfy4
WD repeat and FYVE domain containing 4
chr9_+_123021315 0.42 ENSMUST00000084733.5
Tmem42
transmembrane protein 42
chr17_-_27513341 0.42 ENSMUST00000118161.1
Grm4
glutamate receptor, metabotropic 4
chr9_-_108305941 0.41 ENSMUST00000044725.7
Tcta
T cell leukemia translocation altered gene
chr8_-_105295934 0.40 ENSMUST00000057855.3
Exoc3l
exocyst complex component 3-like
chr11_-_96916448 0.38 ENSMUST00000103152.4
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr10_+_112083345 0.38 ENSMUST00000148897.1
ENSMUST00000020434.3
Glipr1l2
GLI pathogenesis-related 1 like 2
chr16_-_44332925 0.36 ENSMUST00000136381.1
Sidt1
SID1 transmembrane family, member 1
chr11_-_103344651 0.36 ENSMUST00000041385.7
Arhgap27
Rho GTPase activating protein 27
chr3_-_141931523 0.34 ENSMUST00000106232.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr11_+_118443471 0.33 ENSMUST00000133558.1
C1qtnf1
C1q and tumor necrosis factor related protein 1
chr11_-_59079710 0.32 ENSMUST00000133040.1
Obscn
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr9_-_44735189 0.31 ENSMUST00000034611.8
Phldb1
pleckstrin homology-like domain, family B, member 1
chr5_+_134099704 0.30 ENSMUST00000016088.8
Gatsl2
GATS protein-like 2
chr8_-_120177440 0.28 ENSMUST00000048786.6
Fam92b
family with sequence similarity 92, member B
chr15_-_76616841 0.27 ENSMUST00000073428.5
Slc39a4
solute carrier family 39 (zinc transporter), member 4
chr8_-_79248537 0.27 ENSMUST00000034109.4
1700011L22Rik
RIKEN cDNA 1700011L22 gene
chr12_+_78691516 0.26 ENSMUST00000077968.4
Fam71d
family with sequence similarity 71, member D
chr11_-_96916407 0.26 ENSMUST00000130774.1
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr7_-_99182681 0.26 ENSMUST00000033001.4
Dgat2
diacylglycerol O-acyltransferase 2
chr2_+_71981184 0.24 ENSMUST00000090826.5
ENSMUST00000102698.3
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr8_+_70863127 0.22 ENSMUST00000050921.2
A230052G05Rik
RIKEN cDNA A230052G05 gene
chr7_-_25718976 0.22 ENSMUST00000002683.2
Ccdc97
coiled-coil domain containing 97
chr6_-_5256226 0.21 ENSMUST00000125686.1
ENSMUST00000031773.2
Pon3
paraoxonase 3
chr4_+_152297205 0.21 ENSMUST00000048892.7
Icmt
isoprenylcysteine carboxyl methyltransferase
chr11_+_49247462 0.20 ENSMUST00000109194.1
Mgat1
mannoside acetylglucosaminyltransferase 1
chrX_+_101383726 0.19 ENSMUST00000119190.1
Gjb1
gap junction protein, beta 1
chr11_-_96916366 0.19 ENSMUST00000144731.1
ENSMUST00000127048.1
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr17_+_47769191 0.17 ENSMUST00000160373.1
ENSMUST00000159641.1
Tfeb
transcription factor EB
chr15_-_79774408 0.15 ENSMUST00000023055.6
Dnal4
dynein, axonemal, light chain 4
chr18_+_37477768 0.15 ENSMUST00000051442.5
Pcdhb16
protocadherin beta 16
chr9_+_106477269 0.14 ENSMUST00000047721.8
Rrp9
RRP9, small subunit (SSU) processome component, homolog (yeast)
chr1_-_171607321 0.14 ENSMUST00000111277.1
ENSMUST00000004827.7
Ly9
lymphocyte antigen 9
chr1_+_92910805 0.13 ENSMUST00000179711.1
Rnpepl1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr15_-_79774383 0.13 ENSMUST00000069877.5
Dnal4
dynein, axonemal, light chain 4
chr15_-_98004695 0.10 ENSMUST00000023123.8
Col2a1
collagen, type II, alpha 1
chr11_-_70322520 0.10 ENSMUST00000019051.2
Alox12e
arachidonate lipoxygenase, epidermal
chr11_-_100441058 0.09 ENSMUST00000107399.2
ENSMUST00000092688.5
Nt5c3b
5'-nucleotidase, cytosolic IIIB
chr10_+_88201158 0.09 ENSMUST00000171151.2
Ccdc53
coiled-coil domain containing 53
chr15_-_98004634 0.08 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1
collagen, type II, alpha 1
chr9_-_106476372 0.07 ENSMUST00000123555.1
ENSMUST00000125850.1
Parp3
poly (ADP-ribose) polymerase family, member 3
chr7_-_4532419 0.06 ENSMUST00000094897.4
Dnaaf3
dynein, axonemal assembly factor 3
chr11_+_50131342 0.06 ENSMUST00000093138.6
ENSMUST00000101270.4
Tbc1d9b
TBC1 domain family, member 9B
chr11_+_66956620 0.05 ENSMUST00000150220.1
9130409J20Rik
RIKEN cDNA 9130409J20 gene
chr6_+_83078339 0.04 ENSMUST00000165164.2
ENSMUST00000092614.2
Pcgf1
polycomb group ring finger 1
chr19_-_7241216 0.04 ENSMUST00000025675.9
Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chrY_-_40391443 0.03 ENSMUST00000178865.1
Gm21801
predicted gene, 21801
chrY_-_40457264 0.03 ENSMUST00000178452.1
Gm21914
predicted gene, 21914
chr4_-_12087912 0.03 ENSMUST00000050686.3
Tmem67
transmembrane protein 67
chr1_-_171607378 0.03 ENSMUST00000068878.7
Ly9
lymphocyte antigen 9
chr10_+_79034723 0.02 ENSMUST00000082244.2
Olfr57
olfactory receptor 57
chrY_+_32159845 0.01 ENSMUST00000178692.1
Gm21723
predicted gene, 21723
chrY_+_32221125 0.01 ENSMUST00000179646.1
Gm21821
predicted gene, 21821
chrY_+_32283545 0.01 ENSMUST00000177552.1
Gm21842
predicted gene, 21842
chrY_-_30906508 0.01 ENSMUST00000177925.1
Gm21539
predicted gene, 21539
chrY_-_31736484 0.01 ENSMUST00000177888.1
Gm21562
predicted gene, 21562
chrY_-_31802731 0.01 ENSMUST00000180134.1
Gm21572
predicted gene, 21572
chrY_-_32779761 0.01 ENSMUST00000178249.1
Gm21599
predicted gene, 21599
chrY_-_33636191 0.01 ENSMUST00000177791.1
Gm21626
predicted gene, 21626
chrY_-_33702857 0.01 ENSMUST00000178941.1
Gm21633
predicted gene, 21633
chr11_+_70017085 0.01 ENSMUST00000108589.2
Dlg4
discs, large homolog 4 (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of Ptf1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
1.0 3.0 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.7 109.6 GO:0007586 digestion(GO:0007586)
0.6 1.9 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.5 1.4 GO:2000412 lymphocyte migration into lymphoid organs(GO:0097021) positive regulation of thymocyte migration(GO:2000412) regulation of dendritic cell dendrite assembly(GO:2000547)
0.5 1.4 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.4 0.8 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.4 1.5 GO:0006069 ethanol oxidation(GO:0006069)
0.3 1.0 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
0.3 1.2 GO:0034760 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.3 0.5 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.2 0.7 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.2 0.9 GO:0015886 heme transport(GO:0015886)
0.1 1.1 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.5 GO:0060857 establishment of glial blood-brain barrier(GO:0060857)
0.1 0.5 GO:0060447 peripheral nervous system axon regeneration(GO:0014012) bud outgrowth involved in lung branching(GO:0060447)
0.1 0.8 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 15.0 GO:0031638 zymogen activation(GO:0031638)
0.1 0.8 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.3 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.4 GO:0072675 osteoclast fusion(GO:0072675)
0.1 0.2 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.1 0.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.2 GO:0046271 coumarin metabolic process(GO:0009804) phenylpropanoid catabolic process(GO:0046271)
0.1 0.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.4 GO:1905049 negative regulation of metallopeptidase activity(GO:1905049)
0.1 1.4 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 1.0 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.1 0.2 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 1.0 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 18.2 GO:0006887 exocytosis(GO:0006887)
0.0 3.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 6.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0009814 defense response, incompatible interaction(GO:0009814) defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.0 0.4 GO:0033227 dsRNA transport(GO:0033227)
0.0 1.0 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.3 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.2 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.8 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.2 GO:0060174 limb bud formation(GO:0060174)
0.0 0.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 1.2 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.6 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 15.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 18.8 GO:0030667 secretory granule membrane(GO:0030667)
0.1 16.8 GO:0072562 blood microparticle(GO:0072562)
0.1 101.5 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 2.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.4 GO:0031526 brush border membrane(GO:0031526)
0.0 0.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.5 112.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.5 1.5 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.3 2.1 GO:0005499 vitamin D binding(GO:0005499)
0.3 1.1 GO:0042806 fucose binding(GO:0042806)
0.3 1.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 5.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.2 0.9 GO:0015232 heme transporter activity(GO:0015232)
0.2 0.8 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.1 1.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.3 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.7 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.2 GO:0004063 aryldialkylphosphatase activity(GO:0004063)
0.1 0.4 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.4 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 0.5 GO:0045545 syndecan binding(GO:0045545)
0.1 0.2 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 3.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.5 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.8 GO:0017166 vinculin binding(GO:0017166)
0.0 0.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.6 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 2.9 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 1.2 GO:0005507 copper ion binding(GO:0005507)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 23.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.7 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 1.4 PID IL2 1PATHWAY IL2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 26.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.6 7.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 3.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.4 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.8 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP