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GSE58827: Dynamics of the Mouse Liver

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Results for Sox15

Z-value: 0.55

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Transcription factors associated with Sox15

Gene Symbol Gene ID Gene Info
Sox15
ENSMUSG00000041287.5 SRY (sex determining region Y)-box 15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox15mm10_v2_chr11_+_69655314_696553140.625.4e-05Click!

Activity profile of Sox15 motif

Sorted Z-values of Sox15 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_134915512 9.25 ENSMUST00000008987.4
Cldn13
claudin 13
chr6_+_86628174 4.18 ENSMUST00000043400.6
Asprv1
aspartic peptidase, retroviral-like 1
chr9_-_103480328 3.28 ENSMUST00000124310.2
Bfsp2
beaded filament structural protein 2, phakinin
chr16_-_18621366 3.27 ENSMUST00000051160.2
Gp1bb
glycoprotein Ib, beta polypeptide
chr10_+_43579161 3.13 ENSMUST00000058714.8
Cd24a
CD24a antigen
chr12_+_24708984 2.49 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr18_+_82554463 2.13 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
Mbp
myelin basic protein
chr2_-_84822546 2.03 ENSMUST00000028471.5
Smtnl1
smoothelin-like 1
chr11_+_11685909 1.93 ENSMUST00000065433.5
Ikzf1
IKAROS family zinc finger 1
chr11_+_11686213 1.93 ENSMUST00000076700.4
ENSMUST00000048122.6
Ikzf1
IKAROS family zinc finger 1
chr13_+_21722057 1.78 ENSMUST00000110476.3
Hist1h2bm
histone cluster 1, H2bm
chr14_-_70766598 1.77 ENSMUST00000167242.1
ENSMUST00000022696.6
Xpo7
exportin 7
chr10_+_53596936 1.73 ENSMUST00000020004.6
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr2_-_170406501 1.56 ENSMUST00000154650.1
Bcas1
breast carcinoma amplified sequence 1
chr19_+_44293676 1.49 ENSMUST00000026221.5
Scd2
stearoyl-Coenzyme A desaturase 2
chr1_+_136131382 1.49 ENSMUST00000075164.4
Kif21b
kinesin family member 21B
chr18_+_34625009 1.43 ENSMUST00000166044.1
Kif20a
kinesin family member 20A
chr7_+_45216671 1.43 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr10_+_88091070 1.40 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr3_+_131110350 1.37 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1
lymphoid enhancer binding factor 1
chr18_+_34624621 1.35 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr10_-_30655859 1.24 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr16_+_17146937 1.17 ENSMUST00000115706.1
ENSMUST00000069064.4
Ydjc
YdjC homolog (bacterial)
chr6_+_17065129 1.03 ENSMUST00000115467.4
ENSMUST00000154266.2
ENSMUST00000076654.7
Tes
testis derived transcript
chr14_-_54994541 1.00 ENSMUST00000153783.1
ENSMUST00000168485.1
ENSMUST00000102803.3
Myh7
myosin, heavy polypeptide 7, cardiac muscle, beta
chr6_+_86404257 0.97 ENSMUST00000095752.2
ENSMUST00000130967.1
Tia1
cytotoxic granule-associated RNA binding protein 1
chr6_+_86404336 0.95 ENSMUST00000113713.2
ENSMUST00000113708.1
Tia1
cytotoxic granule-associated RNA binding protein 1
chrX_+_112604274 0.91 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chr11_+_87760533 0.90 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1
benzodiazepine receptor associated protein 1
chr5_+_30711564 0.90 ENSMUST00000114729.1
Dpysl5
dihydropyrimidinase-like 5
chr5_-_134946917 0.89 ENSMUST00000051401.2
Cldn4
claudin 4
chr6_-_148944750 0.85 ENSMUST00000111562.1
ENSMUST00000081956.5
Fam60a
family with sequence similarity 60, member A
chr10_+_17796256 0.84 ENSMUST00000037964.6
Txlnb
taxilin beta
chr11_-_106349389 0.84 ENSMUST00000021056.7
Scn4a
sodium channel, voltage-gated, type IV, alpha
chr6_+_86404219 0.83 ENSMUST00000095754.3
ENSMUST00000095753.2
Tia1
cytotoxic granule-associated RNA binding protein 1
chr19_-_46039621 0.83 ENSMUST00000056931.7
Ldb1
LIM domain binding 1
chr4_-_83021102 0.83 ENSMUST00000071708.5
Frem1
Fras1 related extracellular matrix protein 1
chr3_-_64287417 0.81 ENSMUST00000170244.1
ENSMUST00000176328.1
Vmn2r3
vomeronasal 2, receptor 3
chr17_+_47140942 0.80 ENSMUST00000077951.7
Trerf1
transcriptional regulating factor 1
chr9_+_110763646 0.80 ENSMUST00000079784.7
Myl3
myosin, light polypeptide 3
chr14_-_121965128 0.78 ENSMUST00000049872.7
Gpr183
G protein-coupled receptor 183
chr5_+_33983437 0.77 ENSMUST00000114384.1
ENSMUST00000094869.5
ENSMUST00000114383.1
Gm1673
predicted gene 1673
chr6_+_122513643 0.76 ENSMUST00000118626.1
Mfap5
microfibrillar associated protein 5
chr10_-_37138863 0.76 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr18_+_11633276 0.74 ENSMUST00000115861.2
Rbbp8
retinoblastoma binding protein 8
chr6_+_122513583 0.72 ENSMUST00000032210.7
ENSMUST00000148517.1
Mfap5
microfibrillar associated protein 5
chr7_-_115824699 0.72 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr6_+_122513676 0.71 ENSMUST00000142896.1
ENSMUST00000121656.1
Mfap5
microfibrillar associated protein 5
chr5_+_30711849 0.71 ENSMUST00000088081.4
ENSMUST00000101442.3
Dpysl5
dihydropyrimidinase-like 5
chr5_+_33983534 0.70 ENSMUST00000114382.1
Gm1673
predicted gene 1673
chr4_-_129121889 0.68 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
Hpca
hippocalcin
chr7_+_82174796 0.65 ENSMUST00000032874.7
Sh3gl3
SH3-domain GRB2-like 3
chr4_+_5724304 0.65 ENSMUST00000108380.1
Fam110b
family with sequence similarity 110, member B
chr5_+_66968559 0.63 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr14_+_79451791 0.62 ENSMUST00000100359.1
Zbtbd6
kelch repeat and BTB (POZ) domain containing 6
chr19_-_7241216 0.62 ENSMUST00000025675.9
Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr2_+_3114220 0.60 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr6_+_125552948 0.60 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf
Von Willebrand factor homolog
chr11_+_96323253 0.59 ENSMUST00000093944.3
Hoxb3
homeobox B3
chr11_+_67171027 0.59 ENSMUST00000170159.1
Myh2
myosin, heavy polypeptide 2, skeletal muscle, adult
chrX_-_59568068 0.58 ENSMUST00000119833.1
ENSMUST00000131319.1
Fgf13
fibroblast growth factor 13
chr16_-_5013505 0.58 ENSMUST00000023191.10
ENSMUST00000090453.5
Rogdi
rogdi homolog (Drosophila)
chr5_+_19907502 0.57 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_+_4559742 0.53 ENSMUST00000176828.1
Frmd4a
FERM domain containing 4A
chrX_-_167209149 0.53 ENSMUST00000112176.1
Tmsb4x
thymosin, beta 4, X chromosome
chr11_-_49712674 0.52 ENSMUST00000020624.6
ENSMUST00000145353.1
Cnot6
CCR4-NOT transcription complex, subunit 6
chr5_+_66968416 0.51 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr11_-_87074055 0.49 ENSMUST00000020804.7
Gdpd1
glycerophosphodiester phosphodiesterase domain containing 1
chr3_+_94643112 0.47 ENSMUST00000107276.1
Gm10972
predicted gene 10972
chr4_-_129742275 0.46 ENSMUST00000066257.5
Khdrbs1
KH domain containing, RNA binding, signal transduction associated 1
chrX_-_59567348 0.42 ENSMUST00000124402.1
Fgf13
fibroblast growth factor 13
chr17_-_78684262 0.40 ENSMUST00000145480.1
Strn
striatin, calmodulin binding protein
chr15_-_13173607 0.40 ENSMUST00000036439.4
Cdh6
cadherin 6
chrX_+_71556874 0.39 ENSMUST00000123100.1
Hmgb3
high mobility group box 3
chr2_-_84425258 0.39 ENSMUST00000074262.2
Calcrl
calcitonin receptor-like
chr3_+_37639985 0.39 ENSMUST00000108107.1
Spry1
sprouty homolog 1 (Drosophila)
chr18_+_82914632 0.37 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr13_+_118714678 0.33 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr16_+_25801907 0.33 ENSMUST00000040231.6
ENSMUST00000115306.1
ENSMUST00000115304.1
ENSMUST00000115305.1
Trp63
transformation related protein 63
chr1_+_55406163 0.32 ENSMUST00000042986.8
Plcl1
phospholipase C-like 1
chr19_-_46962301 0.32 ENSMUST00000168536.1
Nt5c2
5'-nucleotidase, cytosolic II
chr9_-_75597643 0.31 ENSMUST00000164100.1
Tmod2
tropomodulin 2
chr15_-_79658749 0.29 ENSMUST00000109646.2
Fam227a
family with sequence similarity 227, member A
chr2_-_60125651 0.29 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chrX_+_112600526 0.28 ENSMUST00000113409.1
Zfp711
zinc finger protein 711
chr1_+_87404916 0.28 ENSMUST00000173152.1
ENSMUST00000173663.1
Gigyf2
GRB10 interacting GYF protein 2
chr16_-_46120238 0.28 ENSMUST00000023336.9
Cd96
CD96 antigen
chr2_-_65567465 0.27 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr7_-_78577771 0.26 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chrX_-_57393020 0.25 ENSMUST00000143310.1
ENSMUST00000098470.2
ENSMUST00000114726.1
Rbmx
RNA binding motif protein, X chromosome
chr4_+_19280850 0.25 ENSMUST00000102999.1
Cngb3
cyclic nucleotide gated channel beta 3
chr3_+_58415689 0.24 ENSMUST00000099090.2
Tsc22d2
TSC22 domain family, member 2
chr18_+_37307445 0.24 ENSMUST00000056712.2
Pcdhb4
protocadherin beta 4
chr9_-_108649349 0.23 ENSMUST00000013338.8
Arih2
ariadne homolog 2 (Drosophila)
chr19_-_41848076 0.23 ENSMUST00000059231.2
Frat2
frequently rearranged in advanced T cell lymphomas 2
chr1_+_180330470 0.23 ENSMUST00000070181.6
Itpkb
inositol 1,4,5-trisphosphate 3-kinase B
chr6_-_121003099 0.21 ENSMUST00000098457.2
ENSMUST00000150503.1
Mical3
microtubule associated monooxygenase, calponin and LIM domain containing 3
chr5_+_148265202 0.20 ENSMUST00000110515.2
Mtus2
microtubule associated tumor suppressor candidate 2
chr18_+_33464163 0.19 ENSMUST00000097634.3
Gm10549
predicted gene 10549
chr19_+_55741810 0.19 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr6_-_52240841 0.18 ENSMUST00000121043.1
Hoxa10
homeobox A10
chr9_-_35267746 0.18 ENSMUST00000125087.1
ENSMUST00000121564.1
ENSMUST00000063782.5
ENSMUST00000059057.7
Fam118b
family with sequence similarity 118, member B
chr3_+_31902666 0.16 ENSMUST00000119970.1
ENSMUST00000178668.1
Kcnmb2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chrX_+_73757069 0.16 ENSMUST00000002079.6
Plxnb3
plexin B3
chr5_-_123721007 0.15 ENSMUST00000031376.7
Zcchc8
zinc finger, CCHC domain containing 8
chr6_-_113934679 0.15 ENSMUST00000101044.2
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr6_-_138422898 0.14 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
Lmo3
LIM domain only 3
chr14_+_79515618 0.14 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr18_-_34624562 0.13 ENSMUST00000003876.3
ENSMUST00000115766.1
ENSMUST00000097626.3
ENSMUST00000115765.1
Brd8
bromodomain containing 8
chr19_+_8764934 0.13 ENSMUST00000184663.1
Nxf1
nuclear RNA export factor 1
chr11_-_50292302 0.13 ENSMUST00000059458.4
Maml1
mastermind like 1 (Drosophila)
chr15_+_99702278 0.11 ENSMUST00000023759.4
Smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr2_-_116067391 0.10 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr3_+_31902507 0.10 ENSMUST00000119310.1
Kcnmb2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr3_-_8964037 0.10 ENSMUST00000091354.5
ENSMUST00000094381.4
Tpd52
tumor protein D52
chrX_-_57392962 0.09 ENSMUST00000114730.1
Rbmx
RNA binding motif protein, X chromosome
chr7_+_82175156 0.08 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr8_+_22808275 0.08 ENSMUST00000068068.4
1700041G16Rik
RIKEN cDNA 1700041G16 gene
chr4_+_128688726 0.05 ENSMUST00000106080.1
Phc2
polyhomeotic-like 2 (Drosophila)
chr18_+_43764317 0.04 ENSMUST00000043803.6
Scgb3a2
secretoglobin, family 3A, member 2
chr2_+_29346803 0.04 ENSMUST00000028139.4
ENSMUST00000113830.4
Med27
mediator complex subunit 27
chr7_+_82867327 0.03 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr6_-_52165413 0.02 ENSMUST00000014848.8
Hoxa2
homeobox A2
chr16_-_10796815 0.01 ENSMUST00000023144.5
Prm1
protamine 1
chr14_-_79771305 0.00 ENSMUST00000039568.5
Pcdh8
protocadherin 8

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox15

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
1.0 3.1 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
0.7 2.1 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.5 1.4 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.4 1.5 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.3 1.4 GO:0061153 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.3 0.3 GO:0060667 fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.3 0.3 GO:0060529 squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.3 2.8 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.3 0.8 GO:2000458 astrocyte chemotaxis(GO:0035700) regulation of astrocyte chemotaxis(GO:2000458)
0.2 0.7 GO:0031283 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.2 0.8 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.2 1.0 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.2 3.3 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.7 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 2.8 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 1.0 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 2.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.8 GO:0015871 choline transport(GO:0015871)
0.1 1.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.5 GO:2000325 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.1 0.4 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 2.6 GO:0014823 response to activity(GO:0014823)
0.1 0.6 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.4 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.4 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 2.2 GO:0097435 fibril organization(GO:0097435)
0.1 0.3 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.1 0.7 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.3 GO:0048691 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.1 0.6 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.2 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.1 0.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 1.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.4 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.2 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.3 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.8 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.5 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.2 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.1 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.8 GO:0051764 actin crosslink formation(GO:0051764)
0.0 2.0 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.8 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 1.8 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.0 GO:0021658 rhombomere 3 morphogenesis(GO:0021658)
0.0 3.9 GO:0007596 blood coagulation(GO:0007596)
0.0 0.5 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0006337 nucleosome disassembly(GO:0006337)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.5 1.4 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.3 2.8 GO:0097165 nuclear stress granule(GO:0097165)
0.3 2.1 GO:0033269 internode region of axon(GO:0033269)
0.3 3.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.3 0.8 GO:0042585 germinal vesicle(GO:0042585)
0.1 1.0 GO:0005859 muscle myosin complex(GO:0005859)
0.1 1.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 3.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 2.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 11.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 4.3 GO:0005871 kinesin complex(GO:0005871)
0.1 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.7 GO:0044327 dendritic spine head(GO:0044327)
0.0 2.0 GO:0031430 M band(GO:0031430)
0.0 0.8 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.8 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 3.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.9 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0000812 Swr1 complex(GO:0000812)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.5 2.5 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.4 1.5 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.2 1.4 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 3.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 1.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 0.8 GO:0008142 oxysterol binding(GO:0008142)
0.1 3.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 4.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 4.3 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.1 0.4 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 2.3 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.6 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 2.8 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.7 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 4.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.6 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 1.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID AURORA B PATHWAY Aurora B signaling
0.0 3.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 3.2 PID E2F PATHWAY E2F transcription factor network
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 2.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.4 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.8 REACTOME KINESINS Genes involved in Kinesins
0.1 1.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization