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GSE58827: Dynamics of the Mouse Liver

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Results for Sox5_Sry

Z-value: 0.90

Motif logo

Transcription factors associated with Sox5_Sry

Gene Symbol Gene ID Gene Info
ENSMUSG00000041540.10 SRY (sex determining region Y)-box 5
ENSMUSG00000069036.3 sex determining region of Chr Y

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox5mm10_v2_chr6_-_144209448_1442094690.307.5e-02Click!
Srymm10_v2_chrY_-_2663658_2663658-0.038.8e-01Click!

Activity profile of Sox5_Sry motif

Sorted Z-values of Sox5_Sry motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_102658640 3.09 ENSMUST00000080210.3
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr11_+_94044241 2.88 ENSMUST00000103168.3
sperm associated antigen 9
chr11_+_94044194 2.85 ENSMUST00000092777.4
ENSMUST00000075695.6
sperm associated antigen 9
chr6_+_15185203 2.50 ENSMUST00000154448.1
forkhead box P2
chr11_+_94044111 2.34 ENSMUST00000132079.1
sperm associated antigen 9
chr11_+_94044331 2.24 ENSMUST00000024979.8
sperm associated antigen 9
chr12_-_99393010 2.06 ENSMUST00000177451.1
forkhead box N3
chr6_+_17491216 1.74 ENSMUST00000080469.5
met proto-oncogene
chr5_+_42067960 1.73 ENSMUST00000087332.4
predicted gene 16223
chr10_+_87859593 1.71 ENSMUST00000126490.1
insulin-like growth factor 1
chr2_+_126034967 1.58 ENSMUST00000110442.1
fibroblast growth factor 7
chr10_+_87859481 1.58 ENSMUST00000121952.1
insulin-like growth factor 1
chr7_+_16310412 1.33 ENSMUST00000136781.1
BCL2 binding component 3
chr10_+_87859062 1.32 ENSMUST00000095360.4
insulin-like growth factor 1
chr2_+_126034647 1.30 ENSMUST00000064794.7
fibroblast growth factor 7
chr10_+_87859255 1.24 ENSMUST00000105300.2
insulin-like growth factor 1
chr2_-_6722187 1.21 ENSMUST00000182657.1
CUGBP, Elav-like family member 2
chr19_-_56822161 1.21 ENSMUST00000118592.1
RIKEN cDNA A630007B06 gene
chr7_+_16309577 1.03 ENSMUST00000002152.6
BCL2 binding component 3
chr14_-_54994541 1.01 ENSMUST00000153783.1
ENSMUST00000168485.1
ENSMUST00000102803.3
myosin, heavy polypeptide 7, cardiac muscle, beta
chr3_-_92083132 1.00 ENSMUST00000058150.6
loricrin
chr16_-_16560046 0.99 ENSMUST00000172181.2
FYVE, RhoGEF and PH domain containing 4
chr4_-_82505274 0.99 ENSMUST00000050872.8
ENSMUST00000064770.2
nuclear factor I/B
chr5_-_86518578 0.94 ENSMUST00000134179.1
transmembrane protease, serine 11g
chr1_-_72212249 0.94 ENSMUST00000048860.7
melanoregulin
chr3_+_63295815 0.91 ENSMUST00000029400.1
membrane metallo endopeptidase
chr18_+_44334062 0.88 ENSMUST00000025349.5
ENSMUST00000115498.1
myotilin
chr4_-_70534904 0.88 ENSMUST00000107359.2
multiple EGF-like-domains 9
chr8_+_12385769 0.88 ENSMUST00000080795.8
predicted gene 5607
chr12_+_40446050 0.87 ENSMUST00000037488.6
dedicator of cytokinesis 4
chr10_+_87861309 0.87 ENSMUST00000122100.1
insulin-like growth factor 1
chr6_+_15185456 0.87 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
forkhead box P2
chr19_-_4334001 0.86 ENSMUST00000176653.1
lysine (K)-specific demethylase 2A
chr9_+_110763646 0.84 ENSMUST00000079784.7
myosin, light polypeptide 3
chr2_-_37703275 0.83 ENSMUST00000072186.5
spermatid perinuclear RNA binding protein
chr11_-_3863895 0.81 ENSMUST00000070552.7
oxysterol binding protein 2
chr8_-_84773381 0.81 ENSMUST00000109764.1
nuclear factor I/X
chr16_-_57754707 0.80 ENSMUST00000089332.4
collagen, type VIII, alpha 1
chr11_-_98329641 0.80 ENSMUST00000041685.6
neurogenic differentiation 2
chr11_-_5950018 0.79 ENSMUST00000102920.3
glucokinase
chr9_-_29412204 0.78 ENSMUST00000115237.1
neurotrimin
chr6_+_120364094 0.77 ENSMUST00000100996.3
ENSMUST00000005108.7
lysine (K)-specific demethylase 5A
chr9_-_29411736 0.76 ENSMUST00000115236.1
neurotrimin
chr16_-_95459245 0.76 ENSMUST00000176345.1
ENSMUST00000121809.2
ENSMUST00000118113.1
ENSMUST00000122199.1
avian erythroblastosis virus E-26 (v-ets) oncogene related
chr16_-_4213404 0.75 ENSMUST00000023165.6
CREB binding protein
chr10_+_34483400 0.74 ENSMUST00000019913.7
ENSMUST00000170771.1
fyn-related kinase
chr19_+_23141183 0.72 ENSMUST00000036884.1
Kruppel-like factor 9
chr12_-_83597140 0.71 ENSMUST00000048319.4
zinc finger, FYVE domain containing 1
chr6_-_71440623 0.71 ENSMUST00000002292.8
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr3_+_129532386 0.70 ENSMUST00000071402.2
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr1_-_130940073 0.70 ENSMUST00000112465.1
interleukin 19
chr4_-_83486178 0.69 ENSMUST00000130626.1
PC4 and SFRS1 interacting protein 1
chr5_+_122100951 0.69 ENSMUST00000014080.6
ENSMUST00000111750.1
ENSMUST00000139213.1
ENSMUST00000111751.1
ENSMUST00000155612.1
myosin, light polypeptide 2, regulatory, cardiac, slow
chr2_+_4718145 0.69 ENSMUST00000056914.6
BEN domain containing 7
chr1_+_51289106 0.67 ENSMUST00000051572.6
serum deprivation response
chr18_-_84086379 0.67 ENSMUST00000060303.8
teashirt zinc finger family member 1
chr5_-_92083667 0.67 ENSMUST00000113127.3
GTPase activating protein (SH3 domain) binding protein 2
chr9_+_47530173 0.66 ENSMUST00000114548.1
ENSMUST00000152459.1
ENSMUST00000143026.1
ENSMUST00000085909.2
ENSMUST00000114547.1
ENSMUST00000034581.3
cell adhesion molecule 1
chr14_+_61607455 0.65 ENSMUST00000051184.8
potassium channel regulator
chr6_-_28126125 0.65 ENSMUST00000115324.2
ENSMUST00000090512.3
glutamate receptor, metabotropic 8
chr2_-_169405435 0.65 ENSMUST00000131509.1
RIKEN cDNA 4930529I22 gene
chr4_-_82505707 0.65 ENSMUST00000107248.1
ENSMUST00000107247.1
nuclear factor I/B
chr4_+_129335593 0.64 ENSMUST00000141235.1
zinc finger and BTB domain containing 8 opposite strand
chr19_+_40831296 0.64 ENSMUST00000119316.1
cyclin J
chr1_+_7088917 0.64 ENSMUST00000061280.10
ENSMUST00000182114.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr16_+_20097554 0.63 ENSMUST00000023509.3
kelch-like 24
chr2_-_71750083 0.63 ENSMUST00000180494.1
predicted gene, 17250
chr15_+_25773985 0.63 ENSMUST00000125667.1
myosin X
chr11_+_67171095 0.62 ENSMUST00000018641.7
myosin, heavy polypeptide 2, skeletal muscle, adult
chr6_-_97205549 0.62 ENSMUST00000164744.1
ENSMUST00000089287.5
ubiquitin-like modifier activating enzyme 3
chrX_+_56963325 0.60 ENSMUST00000096431.3
G protein-coupled receptor 112
chr7_+_119900099 0.60 ENSMUST00000106516.1
LYR motif containing 1
chr12_-_40445754 0.60 ENSMUST00000069692.8
ENSMUST00000069637.7
zinc finger protein 277
chr9_-_13446753 0.60 ENSMUST00000167906.2
predicted gene, 17571
chr18_-_3337539 0.60 ENSMUST00000142690.1
ENSMUST00000025069.4
ENSMUST00000082141.5
ENSMUST00000165086.1
ENSMUST00000149803.1
cAMP responsive element modulator
chrX_+_42151002 0.60 ENSMUST00000123245.1
stromal antigen 2
chr4_-_73950834 0.59 ENSMUST00000095023.1
ENSMUST00000030101.3
RIKEN cDNA 2310002L09 gene
chr2_-_6721890 0.59 ENSMUST00000114927.2
CUGBP, Elav-like family member 2
chr3_+_135825788 0.59 ENSMUST00000167390.1
solute carrier family 39 (metal ion transporter), member 8
chr4_+_43641262 0.58 ENSMUST00000123351.1
ENSMUST00000128549.1
natriuretic peptide receptor 2
chr18_-_3337614 0.58 ENSMUST00000150235.1
ENSMUST00000154470.1
cAMP responsive element modulator
chr9_+_74976096 0.58 ENSMUST00000081746.5
family with sequence similarity 214, member A
chr19_+_53903351 0.57 ENSMUST00000025931.6
ENSMUST00000165617.1
programmed cell death 4
chr1_-_153900198 0.57 ENSMUST00000123490.1
RIKEN cDNA 5830403L16 gene
chr11_+_67171027 0.57 ENSMUST00000170159.1
myosin, heavy polypeptide 2, skeletal muscle, adult
chr13_-_111490028 0.56 ENSMUST00000091236.4
GC-rich promoter binding protein 1
chr4_-_82705735 0.56 ENSMUST00000155821.1
nuclear factor I/B
chr18_-_3337467 0.55 ENSMUST00000154135.1
cAMP responsive element modulator
chr7_-_119895446 0.55 ENSMUST00000098080.2
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr6_-_144209558 0.55 ENSMUST00000111749.1
ENSMUST00000170367.2
SRY-box containing gene 5
chr4_+_108460000 0.55 ENSMUST00000097925.2
zinc finger, CCHC domain containing 11
chr10_+_69706326 0.54 ENSMUST00000182992.1
ankyrin 3, epithelial
chr4_-_58499398 0.54 ENSMUST00000107570.1
lysophosphatidic acid receptor 1
chr16_-_64786321 0.53 ENSMUST00000052588.4
zinc finger protein 654
chr10_-_5069044 0.53 ENSMUST00000095899.3
spectrin repeat containing, nuclear envelope 1
chr9_-_50727921 0.53 ENSMUST00000118707.1
ENSMUST00000034566.8
DIX domain containing 1
chr3_-_97297778 0.53 ENSMUST00000181368.1
predicted gene, 17608
chr10_+_123264076 0.53 ENSMUST00000050756.7
family with sequence similarity 19, member A2
chr4_-_83486453 0.52 ENSMUST00000107214.2
ENSMUST00000107215.2
ENSMUST00000030207.8
PC4 and SFRS1 interacting protein 1
chr8_-_67818284 0.52 ENSMUST00000120071.1
pleckstrin and Sec7 domain containing 3
chr3_-_96926020 0.51 ENSMUST00000062944.5
gap junction protein, alpha 8
chr3_+_53488677 0.50 ENSMUST00000029307.3
stomatin (Epb7.2)-like 3
chr5_+_122101146 0.50 ENSMUST00000147178.1
myosin, light polypeptide 2, regulatory, cardiac, slow
chr4_+_97777780 0.50 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
nuclear factor I/A
chr19_-_29753600 0.49 ENSMUST00000175764.1
RIKEN cDNA 9930021J03 gene
chr7_-_110061319 0.49 ENSMUST00000098110.2
expressed sequence AA474408
chr8_+_56551090 0.48 ENSMUST00000040218.5
ENSMUST00000110322.3
F-box protein 8
chr9_-_50728067 0.48 ENSMUST00000117646.1
DIX domain containing 1
chr4_+_11579647 0.48 ENSMUST00000180239.1
fibrinogen silencer binding protein
chr9_+_120149733 0.47 ENSMUST00000068698.7
ENSMUST00000093773.1
ENSMUST00000111627.1
myelin-associated oligodendrocytic basic protein
chr18_+_24205937 0.47 ENSMUST00000164998.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr6_+_134035691 0.47 ENSMUST00000081028.6
ENSMUST00000111963.1
ets variant gene 6 (TEL oncogene)
chr1_+_160906372 0.46 ENSMUST00000161609.1
RING CCCH (C3H) domains 1
chr6_+_34709610 0.46 ENSMUST00000031775.6
caldesmon 1
chrX_-_143933089 0.46 ENSMUST00000087313.3
doublecortin
chr6_+_29859686 0.46 ENSMUST00000134438.1
S-adenosylhomocysteine hydrolase-like 2
chr13_+_65512678 0.46 ENSMUST00000081471.2
predicted gene 10139
chr2_+_112284561 0.45 ENSMUST00000053666.7
solute carrier family 12, member 6
chr6_+_29859374 0.45 ENSMUST00000115238.3
S-adenosylhomocysteine hydrolase-like 2
chrX_+_140907602 0.45 ENSMUST00000033806.4
V-set and immunoglobulin domain containing 1
chr9_+_99470440 0.45 ENSMUST00000056103.4
RIKEN cDNA 1600029I14 gene
chr6_+_91684061 0.44 ENSMUST00000032185.7
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr6_+_29859662 0.44 ENSMUST00000128927.2
S-adenosylhomocysteine hydrolase-like 2
chr13_-_111490111 0.44 ENSMUST00000047627.7
GC-rich promoter binding protein 1
chr13_+_46669517 0.44 ENSMUST00000099547.3
expressed sequence C78339
chr11_-_58330319 0.44 ENSMUST00000065533.2
predicted gene 9900
chr10_-_18234930 0.43 ENSMUST00000052648.8
ENSMUST00000080860.6
ENSMUST00000173243.1
coiled-coil domain containing 28A
chr10_-_68278713 0.43 ENSMUST00000020106.7
AT rich interactive domain 5B (MRF1-like)
chr9_+_52047150 0.43 ENSMUST00000163153.1
radixin
chr1_+_133045984 0.43 ENSMUST00000077730.5
phosphoinositide-3-kinase, class 2, beta polypeptide
chrM_-_14060 0.42 ENSMUST00000082419.1
mitochondrially encoded NADH dehydrogenase 6
chr15_+_102102926 0.42 ENSMUST00000169627.1
ENSMUST00000046144.9
tensin like C1 domain-containing phosphatase
chr9_-_60838200 0.42 ENSMUST00000063858.7
predicted gene 9869
chr13_-_67360509 0.42 ENSMUST00000185002.1
ENSMUST00000081582.6
Protein Zfp953
zinc finger protein 953
chr4_-_109156610 0.42 ENSMUST00000161363.1
oxysterol binding protein-like 9
chr16_-_16560201 0.41 ENSMUST00000162045.1
ENSMUST00000162124.1
ENSMUST00000161861.1
FYVE, RhoGEF and PH domain containing 4
chr4_+_108459389 0.41 ENSMUST00000106673.1
ENSMUST00000043368.5
zinc finger, CCHC domain containing 11
chr18_+_69344503 0.41 ENSMUST00000114985.3
transcription factor 4
chrX_-_160735747 0.41 ENSMUST00000135856.1
protein phosphatase with EF hand calcium-binding domain 1
chr14_-_68655804 0.40 ENSMUST00000111072.1
ENSMUST00000022642.5
a disintegrin and metallopeptidase domain 28
chr4_-_45489794 0.39 ENSMUST00000146236.1
src homology 2 domain-containing transforming protein B
chr3_+_34649987 0.39 ENSMUST00000099151.2
SRY-box containing gene 2
chr1_+_53061637 0.39 ENSMUST00000027269.5
myostatin
chr10_+_116301374 0.39 ENSMUST00000092167.5
protein tyrosine phosphatase, receptor type, B
chr15_-_58214882 0.38 ENSMUST00000022986.6
F-box protein 32
chr8_-_45382198 0.38 ENSMUST00000093526.6
family with sequence similarity 149, member A
chr1_-_133921393 0.38 ENSMUST00000048432.5
proline arginine-rich end leucine-rich repeat
chr10_-_14718191 0.38 ENSMUST00000020016.4
gap junction protein, epsilon 1
chrX_-_103981242 0.37 ENSMUST00000121153.1
ENSMUST00000070705.4
ring finger protein, LIM domain interacting
chr19_+_40831248 0.37 ENSMUST00000025983.6
ENSMUST00000120057.1
cyclin J
chr10_+_69925766 0.37 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
ankyrin 3, epithelial
chr1_+_16105774 0.37 ENSMUST00000027053.7
retinol dehydrogenase 10 (all-trans)
chr17_+_55445550 0.37 ENSMUST00000025000.3
beta galactoside alpha 2,6 sialyltransferase 2
chr10_+_69925484 0.37 ENSMUST00000182692.1
ENSMUST00000092433.5
ankyrin 3, epithelial
chr2_+_18055203 0.37 ENSMUST00000028076.8
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr1_-_97761538 0.37 ENSMUST00000171129.1
diphosphoinositol pentakisphosphate kinase 2
chr2_+_116067933 0.37 ENSMUST00000156095.1
RIKEN cDNA G630016G05 gene
chr6_-_71632897 0.36 ENSMUST00000065509.4
lysine (K)-specific demethylase 3A
chr9_+_7764041 0.36 ENSMUST00000052865.9
transmembrane protein 123
chr3_+_135825648 0.36 ENSMUST00000180196.1
solute carrier family 39 (metal ion transporter), member 8
chr2_-_58052832 0.36 ENSMUST00000090940.5
ermin, ERM-like protein
chr10_+_69925800 0.36 ENSMUST00000182029.1
ankyrin 3, epithelial
chr8_+_65967157 0.35 ENSMUST00000072482.6
membrane-associated ring finger (C3HC4) 1
chr8_-_60954726 0.35 ENSMUST00000110302.1
chloride channel 3
chr4_+_109343029 0.35 ENSMUST00000030281.5
epidermal growth factor receptor pathway substrate 15
chr10_+_97607166 0.34 ENSMUST00000105286.2
keratocan
chr5_-_86373413 0.34 ENSMUST00000031175.5
transmembrane protease, serine 11d
chr17_+_47436731 0.34 ENSMUST00000150819.2
expressed sequence AI661453
chr14_-_21714570 0.34 ENSMUST00000073870.5
dual specificity phosphatase and pro isomerase domain containing 1
chrX_+_42150672 0.34 ENSMUST00000069619.7
stromal antigen 2
chr12_+_100779074 0.34 ENSMUST00000110073.1
ENSMUST00000110070.1
RIKEN cDNA 9030617O03 gene
chr9_-_72111651 0.34 ENSMUST00000185117.1
transcription factor 12
chr5_-_123140135 0.34 ENSMUST00000160099.1
expressed sequence AI480526
chr9_-_48835932 0.33 ENSMUST00000093852.3
zinc finger and BTB domain containing 16
chr12_+_100779088 0.33 ENSMUST00000110069.1
RIKEN cDNA 9030617O03 gene
chr19_-_40187277 0.33 ENSMUST00000051846.6
cytochrome P450, family 2, subfamily c, polypeptide 70
chr4_+_144893127 0.33 ENSMUST00000142808.1
dehydrogenase/reductase (SDR family) member 3
chr4_+_144893077 0.33 ENSMUST00000154208.1
dehydrogenase/reductase (SDR family) member 3
chr15_+_34082664 0.33 ENSMUST00000022865.9
metadherin
chr12_+_100779055 0.33 ENSMUST00000069782.4
RIKEN cDNA 9030617O03 gene
chr5_+_124862674 0.33 ENSMUST00000111417.2
zinc finger protein 664
chr5_+_14514918 0.33 ENSMUST00000030691.10
ENSMUST00000182407.1
piccolo (presynaptic cytomatrix protein)
chr10_+_69925954 0.32 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
ankyrin 3, epithelial
chr1_+_86526688 0.32 ENSMUST00000045897.8
prothymosin alpha
chr1_-_64121389 0.32 ENSMUST00000055001.3
Kruppel-like factor 7 (ubiquitous)
chr14_-_46575847 0.32 ENSMUST00000151828.1
predicted gene 15219
chr12_-_98577940 0.32 ENSMUST00000110113.1
potassium channel, subfamily K, member 10
chr6_+_139843648 0.32 ENSMUST00000087657.6
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
chr12_-_85270564 0.31 ENSMUST00000019378.6
ENSMUST00000166821.1
mutL homolog 3 (E coli)
chr9_+_54980880 0.31 ENSMUST00000093844.3
cholinergic receptor, nicotinic, alpha polypeptide 5
chr10_+_18407658 0.31 ENSMUST00000037341.7
NHS-like 1
chr15_+_25622525 0.31 ENSMUST00000110457.1
ENSMUST00000137601.1
myosin X
chr11_-_60352869 0.30 ENSMUST00000095254.5
ENSMUST00000102683.4
ENSMUST00000093048.6
ENSMUST00000093046.6
ENSMUST00000064019.8
ENSMUST00000102682.4
target of myb1-like 2 (chicken)
chr6_+_15185439 0.30 ENSMUST00000118133.1
forkhead box P2
chr6_+_15196949 0.30 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
forkhead box P2
chr17_+_4994904 0.30 ENSMUST00000092723.4
ENSMUST00000115797.2
AT rich interactive domain 1B (SWI-like)
chr15_-_44428303 0.30 ENSMUST00000038719.6
NudC domain containing 1
chr16_+_42907563 0.30 ENSMUST00000151244.1
ENSMUST00000114694.2
zinc finger and BTB domain containing 20
chr5_-_123141067 0.30 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
expressed sequence AI480526
chr4_-_103215147 0.29 ENSMUST00000150285.1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox5_Sry

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 10.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
1.1 6.7 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
1.0 2.9 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.6 2.4 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.5 2.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4 3.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 0.9 GO:0071492 cellular response to UV-A(GO:0071492)
0.3 4.0 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.3 0.8 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.3 0.8 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.2 1.7 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.2 0.7 GO:0009826 unidimensional cell growth(GO:0009826)
0.2 0.9 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2 2.4 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.6 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 1.0 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.2 0.6 GO:0036446 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.2 0.8 GO:0045358 negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.2 1.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 1.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 0.8 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.2 1.4 GO:0030035 microspike assembly(GO:0030035)
0.2 0.6 GO:0007113 endomitotic cell cycle(GO:0007113)
0.2 1.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 0.5 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 1.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.4 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.1 0.5 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.5 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.4 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.1 0.4 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.1 0.4 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1 0.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.7 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 0.5 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 0.3 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 0.7 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.7 GO:0060023 soft palate development(GO:0060023)
0.1 0.7 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.3 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.1 0.9 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.1 1.0 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.1 0.9 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.6 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 0.3 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.1 0.2 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.1 0.8 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.3 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 0.7 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.1 0.4 GO:0060431 primary lung bud formation(GO:0060431)
0.1 0.5 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 1.7 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.3 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.3 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.4 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 0.7 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 2.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.1 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.1 0.6 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 1.1 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 0.1 GO:0007403 glial cell fate determination(GO:0007403)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.2 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.3 GO:0007144 female meiosis I(GO:0007144)
0.1 0.4 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.1 0.2 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.5 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.2 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 1.2 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.1 0.7 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.9 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.2 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 0.4 GO:0060613 fat pad development(GO:0060613)
0.1 0.4 GO:0098885 modification of postsynaptic actin cytoskeleton(GO:0098885)
0.1 0.4 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.2 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.1 0.1 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.2 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.0 0.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.3 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.5 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.9 GO:0042640 anagen(GO:0042640)
0.0 0.1 GO:0070543 response to linoleic acid(GO:0070543)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.5 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.3 GO:0048852 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) diencephalon morphogenesis(GO:0048852)
0.0 0.3 GO:0097475 motor neuron migration(GO:0097475)
0.0 1.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0042253 granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0 0.3 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.7 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.7 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.7 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.3 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 1.0 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.7 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.4 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.7 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.3 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.2 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.7 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 0.1 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0 0.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.8 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.6 GO:0010225 response to UV-C(GO:0010225)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 1.0 GO:0031424 keratinization(GO:0031424)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 1.9 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.2 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.8 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.2 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.4 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.0 0.1 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920) regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.0 0.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:2000292 negative regulation of eating behavior(GO:1903999) regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.0 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.3 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.2 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0035802 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802) embryonic heart tube left/right pattern formation(GO:0060971) pulmonary artery morphogenesis(GO:0061156) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.1 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.0 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.0 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.4 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.4 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.2 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.3 GO:0043486 histone exchange(GO:0043486)
0.0 0.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.1 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.1 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.7 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:0070922 small RNA loading onto RISC(GO:0070922)
0.0 0.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.7 GO:0042567 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) insulin-like growth factor ternary complex(GO:0042567)
0.3 1.0 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.2 0.7 GO:0034657 GID complex(GO:0034657)
0.2 1.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.3 GO:0044317 rod spherule(GO:0044317)
0.1 2.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 2.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 3.1 GO:0030673 axolemma(GO:0030673)
0.1 0.8 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 1.2 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.7 GO:0030478 actin cap(GO:0030478)
0.1 0.2 GO:0032437 cuticular plate(GO:0032437)
0.1 0.6 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.7 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.4 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.8 GO:0045180 basal cortex(GO:0045180)
0.0 0.7 GO:0070852 cell body fiber(GO:0070852)
0.0 1.0 GO:0032982 myosin filament(GO:0032982)
0.0 0.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.3 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.4 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 0.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0042581 specific granule(GO:0042581)
0.0 1.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0097386 glial cell projection(GO:0097386)
0.0 0.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.8 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.2 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 12.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.7 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.8 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.7 GO:0042734 presynaptic membrane(GO:0042734)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 10.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.5 3.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 1.7 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.4 2.9 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.3 1.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.3 0.3 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2 1.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 1.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 1.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 0.8 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.2 6.7 GO:0043539 insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539)
0.2 0.5 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.2 1.2 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.1 1.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.4 GO:0030977 taurine binding(GO:0030977)
0.1 0.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.9 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.6 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.7 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.4 GO:0052723 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 0.8 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.1 0.4 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 2.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.2 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.1 0.7 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.6 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0008506 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 2.5 GO:0030507 spectrin binding(GO:0030507)
0.0 1.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 1.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 1.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.7 GO:0005521 lamin binding(GO:0005521)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.2 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 2.7 GO:0051117 ATPase binding(GO:0051117)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.0 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 1.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 1.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.9 GO:0003725 double-stranded RNA binding(GO:0003725)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 10.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 4.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 0.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 3.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID FOXO PATHWAY FoxO family signaling
0.0 0.9 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 3.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.6 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 2.3 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 2.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.0 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 0.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.7 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.8 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 2.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 2.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.7 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1