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GSE58827: Dynamics of the Mouse Liver
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Results for Spib
Z-value: 2.80
Motif logo
Transcription factors associated with Spib
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
Spib
|
ENSMUSG00000008193.7 | Spi-B transcription factor (Spi-1/PU.1 related) |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Spib | mm10_v2_chr7_-_44532064_44532078 | 0.81 | 2.3e-09 | Click! |
Activity profile of Spib motif
Sorted Z-values of Spib motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr14_+_80000292 | 24.32 |
ENSMUST00000088735.3
|
Olfm4
|
olfactomedin 4 |
| chrX_-_7964166 | 23.13 |
ENSMUST00000128449.1
|
Gata1
|
GATA binding protein 1 |
| chr17_+_48232755 | 17.08 |
ENSMUST00000113251.3
ENSMUST00000048782.6 |
Trem1
|
triggering receptor expressed on myeloid cells 1 |
| chr15_-_66812593 | 14.79 |
ENSMUST00000100572.3
|
Sla
|
src-like adaptor |
| chr1_+_174172738 | 14.52 |
ENSMUST00000027817.7
|
Spta1
|
spectrin alpha, erythrocytic 1 |
| chr11_-_17008647 | 14.24 |
ENSMUST00000102881.3
|
Plek
|
pleckstrin |
| chr7_-_100856289 | 14.13 |
ENSMUST00000139604.1
|
Relt
|
RELT tumor necrosis factor receptor |
| chr11_+_11685909 | 13.18 |
ENSMUST00000065433.5
|
Ikzf1
|
IKAROS family zinc finger 1 |
| chr1_+_171767123 | 12.76 |
ENSMUST00000015460.4
|
Slamf1
|
signaling lymphocytic activation molecule family member 1 |
| chr9_+_56089962 | 12.39 |
ENSMUST00000059206.7
|
Pstpip1
|
proline-serine-threonine phosphatase-interacting protein 1 |
| chr5_-_134229581 | 12.18 |
ENSMUST00000111275.1
ENSMUST00000016094.6 ENSMUST00000144086.1 |
Ncf1
|
neutrophil cytosolic factor 1 |
| chr5_+_149265035 | 11.42 |
ENSMUST00000130144.1
ENSMUST00000071130.3 |
Alox5ap
|
arachidonate 5-lipoxygenase activating protein |
| chr7_-_126704736 | 11.16 |
ENSMUST00000131415.1
|
Coro1a
|
coronin, actin binding protein 1A |
| chr2_+_25423234 | 10.96 |
ENSMUST00000134259.1
ENSMUST00000100320.4 |
Fut7
|
fucosyltransferase 7 |
| chr2_-_181691771 | 10.90 |
ENSMUST00000108778.1
ENSMUST00000165416.1 |
Rgs19
|
regulator of G-protein signaling 19 |
| chr2_-_165400398 | 10.26 |
ENSMUST00000029213.4
|
Ocstamp
|
osteoclast stimulatory transmembrane protein |
| chr8_+_72189613 | 10.20 |
ENSMUST00000072097.6
|
Hsh2d
|
hematopoietic SH2 domain containing |
| chr16_-_22657182 | 10.09 |
ENSMUST00000023578.7
|
Dgkg
|
diacylglycerol kinase, gamma |
| chr15_-_78305603 | 9.85 |
ENSMUST00000096356.3
|
Csf2rb2
|
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) |
| chr13_+_30749226 | 9.77 |
ENSMUST00000021784.2
ENSMUST00000110307.1 |
Irf4
|
interferon regulatory factor 4 |
| chr12_-_32208470 | 9.50 |
ENSMUST00000085469.5
|
Pik3cg
|
phosphoinositide-3-kinase, catalytic, gamma polypeptide |
| chr13_-_23465872 | 9.22 |
ENSMUST00000041674.7
|
Btn1a1
|
butyrophilin, subfamily 1, member A1 |
| chr1_-_170927567 | 9.16 |
ENSMUST00000046322.7
ENSMUST00000159171.1 |
Fcrla
|
Fc receptor-like A |
| chr3_-_105932664 | 9.14 |
ENSMUST00000098758.2
|
I830077J02Rik
|
RIKEN cDNA I830077J02 gene |
| chr6_-_136941694 | 9.12 |
ENSMUST00000032344.5
|
Arhgdib
|
Rho, GDP dissociation inhibitor (GDI) beta |
| chr2_+_24345282 | 9.02 |
ENSMUST00000114485.2
|
Il1rn
|
interleukin 1 receptor antagonist |
| chr7_+_99535439 | 9.00 |
ENSMUST00000098266.2
ENSMUST00000179755.1 |
Arrb1
|
arrestin, beta 1 |
| chr9_-_66919646 | 8.88 |
ENSMUST00000041139.7
|
Rab8b
|
RAB8B, member RAS oncogene family |
| chr7_+_43408187 | 8.84 |
ENSMUST00000005592.6
|
Siglecg
|
sialic acid binding Ig-like lectin G |
| chr16_-_22657165 | 8.68 |
ENSMUST00000089925.3
|
Dgkg
|
diacylglycerol kinase, gamma |
| chr7_-_126704522 | 8.62 |
ENSMUST00000135087.1
|
Coro1a
|
coronin, actin binding protein 1A |
| chr2_+_24345305 | 8.54 |
ENSMUST00000114482.1
|
Il1rn
|
interleukin 1 receptor antagonist |
| chr13_-_113100971 | 8.37 |
ENSMUST00000023897.5
|
Gzma
|
granzyme A |
| chr1_-_170927540 | 8.30 |
ENSMUST00000162136.1
ENSMUST00000162887.1 |
Fcrla
|
Fc receptor-like A |
| chr13_+_104228929 | 8.20 |
ENSMUST00000070761.3
|
Cenpk
|
centromere protein K |
| chr10_-_6980376 | 8.15 |
ENSMUST00000105617.1
|
Ipcef1
|
interaction protein for cytohesin exchange factors 1 |
| chr17_+_34604262 | 8.11 |
ENSMUST00000174041.1
|
Agpat1
|
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) |
| chr7_-_45239041 | 8.00 |
ENSMUST00000131290.1
|
Cd37
|
CD37 antigen |
| chr12_-_32208609 | 7.99 |
ENSMUST00000053215.7
|
Pik3cg
|
phosphoinositide-3-kinase, catalytic, gamma polypeptide |
| chr4_-_116123618 | 7.95 |
ENSMUST00000102704.3
ENSMUST00000102705.3 |
Rad54l
|
RAD54 like (S. cerevisiae) |
| chr7_-_45238794 | 7.86 |
ENSMUST00000098461.1
ENSMUST00000107797.1 |
Cd37
|
CD37 antigen |
| chr7_-_126704179 | 7.68 |
ENSMUST00000106364.1
|
Coro1a
|
coronin, actin binding protein 1A |
| chr19_+_6084983 | 7.67 |
ENSMUST00000025704.2
|
Cdca5
|
cell division cycle associated 5 |
| chrX_+_20703906 | 7.61 |
ENSMUST00000033383.2
|
Usp11
|
ubiquitin specific peptidase 11 |
| chr10_+_130322845 | 7.50 |
ENSMUST00000042586.8
|
Tespa1
|
thymocyte expressed, positive selection associated 1 |
| chr1_-_38664947 | 7.23 |
ENSMUST00000039827.7
ENSMUST00000027250.7 |
Aff3
|
AF4/FMR2 family, member 3 |
| chr2_-_181693810 | 7.21 |
ENSMUST00000108776.1
ENSMUST00000108771.1 ENSMUST00000108779.1 ENSMUST00000108769.1 ENSMUST00000108772.1 ENSMUST00000002532.2 |
Rgs19
|
regulator of G-protein signaling 19 |
| chr19_+_4154606 | 7.20 |
ENSMUST00000061086.8
|
Ptprcap
|
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein |
| chr15_+_78325990 | 7.05 |
ENSMUST00000096355.3
|
Csf2rb
|
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| chr11_-_34783850 | 6.96 |
ENSMUST00000093193.5
ENSMUST00000101365.2 |
Dock2
|
dedicator of cyto-kinesis 2 |
| chr7_-_45239108 | 6.95 |
ENSMUST00000033063.6
|
Cd37
|
CD37 antigen |
| chr5_+_134676490 | 6.95 |
ENSMUST00000100641.2
|
Gm10369
|
predicted gene 10369 |
| chr2_+_36216749 | 6.94 |
ENSMUST00000147012.1
ENSMUST00000122948.1 |
Gm13431
|
predicted gene 13431 |
| chr17_+_57279094 | 6.92 |
ENSMUST00000169220.2
ENSMUST00000005889.9 ENSMUST00000112870.4 |
Vav1
|
vav 1 oncogene |
| chr10_+_81257277 | 6.85 |
ENSMUST00000117488.1
ENSMUST00000105328.3 ENSMUST00000121205.1 |
Matk
|
megakaryocyte-associated tyrosine kinase |
| chr6_-_136941494 | 6.67 |
ENSMUST00000111892.1
|
Arhgdib
|
Rho, GDP dissociation inhibitor (GDI) beta |
| chr15_+_103453782 | 6.61 |
ENSMUST00000047405.7
|
Nckap1l
|
NCK associated protein 1 like |
| chr6_+_38918969 | 6.57 |
ENSMUST00000003017.6
|
Tbxas1
|
thromboxane A synthase 1, platelet |
| chr5_+_118560719 | 6.56 |
ENSMUST00000100816.4
|
Med13l
|
mediator complex subunit 13-like |
| chr2_+_22774081 | 6.54 |
ENSMUST00000014290.8
|
Apbb1ip
|
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| chr2_+_91650116 | 6.47 |
ENSMUST00000111331.2
|
Arhgap1
|
Rho GTPase activating protein 1 |
| chr6_+_60944472 | 6.43 |
ENSMUST00000129603.1
|
Mmrn1
|
multimerin 1 |
| chr13_+_20794119 | 6.27 |
ENSMUST00000021757.3
|
Aoah
|
acyloxyacyl hydrolase |
| chr15_-_78572754 | 6.20 |
ENSMUST00000043214.6
|
Rac2
|
RAS-related C3 botulinum substrate 2 |
| chr8_+_79028317 | 6.14 |
ENSMUST00000087927.4
ENSMUST00000098614.2 |
Zfp827
|
zinc finger protein 827 |
| chr13_-_23465895 | 6.12 |
ENSMUST00000110434.1
|
Btn1a1
|
butyrophilin, subfamily 1, member A1 |
| chrX_+_159708593 | 6.07 |
ENSMUST00000080394.6
|
Sh3kbp1
|
SH3-domain kinase binding protein 1 |
| chr15_-_83033294 | 6.03 |
ENSMUST00000100377.4
|
Nfam1
|
Nfat activating molecule with ITAM motif 1 |
| chr3_+_83766300 | 6.02 |
ENSMUST00000029625.7
|
Sfrp2
|
secreted frizzled-related protein 2 |
| chr1_-_171059390 | 5.95 |
ENSMUST00000164044.1
ENSMUST00000169017.1 |
Fcgr3
|
Fc receptor, IgG, low affinity III |
| chr1_-_173333503 | 5.91 |
ENSMUST00000038227.4
|
Darc
|
Duffy blood group, chemokine receptor |
| chr6_+_129350237 | 5.91 |
ENSMUST00000065289.4
|
Clec12a
|
C-type lectin domain family 12, member a |
| chr1_-_45503282 | 5.89 |
ENSMUST00000086430.4
|
Col5a2
|
collagen, type V, alpha 2 |
| chr2_+_156840966 | 5.87 |
ENSMUST00000109564.1
|
Tgif2
|
TGFB-induced factor homeobox 2 |
| chr12_-_78980758 | 5.87 |
ENSMUST00000174072.1
|
Tmem229b
|
transmembrane protein 229B |
| chr11_+_70130329 | 5.82 |
ENSMUST00000041550.5
ENSMUST00000165951.1 |
Mgl2
|
macrophage galactose N-acetyl-galactosamine specific lectin 2 |
| chr7_-_80387935 | 5.66 |
ENSMUST00000080932.6
|
Fes
|
feline sarcoma oncogene |
| chr2_+_43748802 | 5.62 |
ENSMUST00000112824.1
ENSMUST00000055776.7 |
Arhgap15
|
Rho GTPase activating protein 15 |
| chr15_-_36608959 | 5.62 |
ENSMUST00000001809.8
|
Pabpc1
|
poly(A) binding protein, cytoplasmic 1 |
| chr17_+_7925990 | 5.59 |
ENSMUST00000036370.7
|
Tagap
|
T cell activation Rho GTPase activating protein |
| chr17_+_35049966 | 5.54 |
ENSMUST00000007257.9
|
Clic1
|
chloride intracellular channel 1 |
| chr10_-_62508097 | 5.52 |
ENSMUST00000159020.1
|
Srgn
|
serglycin |
| chr7_-_3720382 | 5.48 |
ENSMUST00000078451.6
|
Pirb
|
paired Ig-like receptor B |
| chr16_-_89960815 | 5.47 |
ENSMUST00000002588.3
|
Tiam1
|
T cell lymphoma invasion and metastasis 1 |
| chr4_+_140701466 | 5.38 |
ENSMUST00000038893.5
ENSMUST00000138808.1 |
Rcc2
|
regulator of chromosome condensation 2 |
| chr11_-_103344651 | 5.32 |
ENSMUST00000041385.7
|
Arhgap27
|
Rho GTPase activating protein 27 |
| chr3_+_99253754 | 5.30 |
ENSMUST00000029462.5
|
Tbx15
|
T-box 15 |
| chr6_-_124733067 | 5.22 |
ENSMUST00000173647.1
|
Ptpn6
|
protein tyrosine phosphatase, non-receptor type 6 |
| chr2_+_91650169 | 5.18 |
ENSMUST00000090614.4
|
Arhgap1
|
Rho GTPase activating protein 1 |
| chr2_+_120463566 | 4.95 |
ENSMUST00000028749.7
ENSMUST00000110721.1 |
Capn3
|
calpain 3 |
| chr8_-_88636117 | 4.93 |
ENSMUST00000034087.7
|
Snx20
|
sorting nexin 20 |
| chr15_-_9529868 | 4.92 |
ENSMUST00000003981.4
|
Il7r
|
interleukin 7 receptor |
| chr2_+_24386604 | 4.90 |
ENSMUST00000166388.1
|
Psd4
|
pleckstrin and Sec7 domain containing 4 |
| chr17_-_67950908 | 4.86 |
ENSMUST00000164647.1
|
Arhgap28
|
Rho GTPase activating protein 28 |
| chr14_+_67745229 | 4.83 |
ENSMUST00000111095.2
|
Gnrh1
|
gonadotropin releasing hormone 1 |
| chr15_-_81045467 | 4.81 |
ENSMUST00000135047.1
|
Mkl1
|
MKL (megakaryoblastic leukemia)/myocardin-like 1 |
| chr2_-_39005574 | 4.74 |
ENSMUST00000080861.5
|
Rpl35
|
ribosomal protein L35 |
| chr11_+_46454957 | 4.73 |
ENSMUST00000109229.1
|
Havcr2
|
hepatitis A virus cellular receptor 2 |
| chr5_-_116024475 | 4.65 |
ENSMUST00000111999.1
|
Prkab1
|
protein kinase, AMP-activated, beta 1 non-catalytic subunit |
| chr11_+_46454921 | 4.56 |
ENSMUST00000020668.8
|
Havcr2
|
hepatitis A virus cellular receptor 2 |
| chr9_+_124101944 | 4.55 |
ENSMUST00000171719.1
|
Ccr2
|
chemokine (C-C motif) receptor 2 |
| chr16_-_36642742 | 4.55 |
ENSMUST00000135280.1
|
Cd86
|
CD86 antigen |
| chr4_+_130913264 | 4.50 |
ENSMUST00000156225.1
ENSMUST00000156742.1 |
Laptm5
|
lysosomal-associated protein transmembrane 5 |
| chr9_+_106203108 | 4.48 |
ENSMUST00000024047.5
|
Twf2
|
twinfilin, actin-binding protein, homolog 2 (Drosophila) |
| chr2_-_93046053 | 4.45 |
ENSMUST00000111272.1
ENSMUST00000178666.1 ENSMUST00000147339.1 |
Prdm11
|
PR domain containing 11 |
| chr16_-_92826004 | 4.43 |
ENSMUST00000023673.7
|
Runx1
|
runt related transcription factor 1 |
| chr1_+_87620306 | 4.41 |
ENSMUST00000169754.1
|
Inpp5d
|
inositol polyphosphate-5-phosphatase D |
| chr9_+_124102110 | 4.39 |
ENSMUST00000168841.1
ENSMUST00000055918.6 |
Ccr2
|
chemokine (C-C motif) receptor 2 |
| chr5_-_38876693 | 4.37 |
ENSMUST00000169819.1
ENSMUST00000171633.1 |
Clnk
|
cytokine-dependent hematopoietic cell linker |
| chr1_+_87620334 | 4.36 |
ENSMUST00000042275.8
ENSMUST00000168783.1 |
Inpp5d
|
inositol polyphosphate-5-phosphatase D |
| chr11_+_46810792 | 4.27 |
ENSMUST00000068877.6
|
Timd4
|
T cell immunoglobulin and mucin domain containing 4 |
| chr13_+_23544052 | 4.26 |
ENSMUST00000075558.2
|
Hist1h3f
|
histone cluster 1, H3f |
| chr19_+_12846773 | 4.25 |
ENSMUST00000164001.1
|
Gm5244
|
predicted pseudogene 5244 |
| chr15_+_58510037 | 4.22 |
ENSMUST00000161028.1
|
Fer1l6
|
fer-1-like 6 (C. elegans) |
| chr3_-_59210881 | 4.17 |
ENSMUST00000040622.1
|
P2ry13
|
purinergic receptor P2Y, G-protein coupled 13 |
| chr3_-_101029543 | 4.16 |
ENSMUST00000147399.2
|
Cd101
|
CD101 antigen |
| chr3_-_95142346 | 4.13 |
ENSMUST00000013851.3
|
Tnfaip8l2
|
tumor necrosis factor, alpha-induced protein 8-like 2 |
| chr7_-_29232478 | 4.12 |
ENSMUST00000085818.4
|
Kcnk6
|
potassium inwardly-rectifying channel, subfamily K, member 6 |
| chr5_+_86071734 | 4.10 |
ENSMUST00000031171.7
|
Stap1
|
signal transducing adaptor family member 1 |
| chr7_-_3898120 | 4.09 |
ENSMUST00000070639.7
|
Gm14548
|
predicted gene 14548 |
| chrX_+_166344692 | 3.99 |
ENSMUST00000112223.1
ENSMUST00000112224.1 ENSMUST00000112229.2 ENSMUST00000112228.1 ENSMUST00000112227.2 ENSMUST00000112226.2 |
Gpm6b
|
glycoprotein m6b |
| chr4_-_92191749 | 3.98 |
ENSMUST00000123179.1
|
Gm12666
|
predicted gene 12666 |
| chr4_+_119195496 | 3.90 |
ENSMUST00000097908.3
|
Ccdc23
|
coiled-coil domain containing 23 |
| chr8_+_10006656 | 3.89 |
ENSMUST00000033892.7
|
Tnfsf13b
|
tumor necrosis factor (ligand) superfamily, member 13b |
| chr1_-_149961230 | 3.81 |
ENSMUST00000070200.8
|
Pla2g4a
|
phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| chr19_+_6399857 | 3.80 |
ENSMUST00000146601.1
ENSMUST00000150713.1 |
Rasgrp2
|
RAS, guanyl releasing protein 2 |
| chr5_+_81021202 | 3.75 |
ENSMUST00000117253.1
ENSMUST00000120128.1 |
Lphn3
|
latrophilin 3 |
| chr8_+_94745590 | 3.73 |
ENSMUST00000034231.3
|
Ccl22
|
chemokine (C-C motif) ligand 22 |
| chr4_+_119195279 | 3.59 |
ENSMUST00000030395.2
|
Ccdc23
|
coiled-coil domain containing 23 |
| chr7_-_126463100 | 3.53 |
ENSMUST00000032974.6
|
Atp2a1
|
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
| chr1_-_171234290 | 3.53 |
ENSMUST00000079957.6
|
Fcer1g
|
Fc receptor, IgE, high affinity I, gamma polypeptide |
| chr7_-_99483645 | 3.52 |
ENSMUST00000107096.1
ENSMUST00000032998.6 |
Rps3
|
ribosomal protein S3 |
| chr4_+_130913120 | 3.51 |
ENSMUST00000151698.1
|
Laptm5
|
lysosomal-associated protein transmembrane 5 |
| chr2_+_91096744 | 3.51 |
ENSMUST00000132741.2
|
Spi1
|
spleen focus forming virus (SFFV) proviral integration oncogene |
| chr4_+_119195353 | 3.47 |
ENSMUST00000106345.2
|
Ccdc23
|
coiled-coil domain containing 23 |
| chr1_-_173227229 | 3.45 |
ENSMUST00000049706.5
|
Fcer1a
|
Fc receptor, IgE, high affinity I, alpha polypeptide |
| chr9_+_106222598 | 3.45 |
ENSMUST00000062241.9
|
Tlr9
|
toll-like receptor 9 |
| chr2_-_105399286 | 3.42 |
ENSMUST00000006128.6
|
Rcn1
|
reticulocalbin 1 |
| chr16_-_36666067 | 3.41 |
ENSMUST00000089620.4
|
Cd86
|
CD86 antigen |
| chr2_-_91649785 | 3.33 |
ENSMUST00000111333.1
|
Zfp408
|
zinc finger protein 408 |
| chr14_-_51988829 | 3.31 |
ENSMUST00000181008.1
|
Gm16617
|
predicted gene, 16617 |
| chrX_-_48454152 | 3.31 |
ENSMUST00000114958.1
|
Elf4
|
E74-like factor 4 (ets domain transcription factor) |
| chr5_-_116024452 | 3.30 |
ENSMUST00000031486.7
|
Prkab1
|
protein kinase, AMP-activated, beta 1 non-catalytic subunit |
| chr13_+_5861489 | 3.28 |
ENSMUST00000000080.6
|
Klf6
|
Kruppel-like factor 6 |
| chr11_-_69323768 | 3.27 |
ENSMUST00000092973.5
|
Cntrob
|
centrobin, centrosomal BRCA2 interacting protein |
| chr3_-_87263518 | 3.23 |
ENSMUST00000090986.4
|
Fcrls
|
Fc receptor-like S, scavenger receptor |
| chr11_+_68432112 | 3.14 |
ENSMUST00000021283.7
|
Pik3r5
|
phosphoinositide-3-kinase, regulatory subunit 5, p101 |
| chr10_+_80265035 | 3.10 |
ENSMUST00000092305.5
|
Dazap1
|
DAZ associated protein 1 |
| chr7_-_127286385 | 3.07 |
ENSMUST00000172206.2
|
Gm17511
|
predicted gene, 17511 |
| chr4_+_115839192 | 3.07 |
ENSMUST00000019677.5
ENSMUST00000144427.1 ENSMUST00000106513.3 ENSMUST00000130819.1 ENSMUST00000151203.1 ENSMUST00000140315.1 |
Mknk1
|
MAP kinase-interacting serine/threonine kinase 1 |
| chr18_+_75000469 | 3.06 |
ENSMUST00000079716.5
|
Rpl17
|
ribosomal protein L17 |
| chr3_-_87263703 | 3.04 |
ENSMUST00000146512.1
|
Fcrls
|
Fc receptor-like S, scavenger receptor |
| chr10_+_81393610 | 3.04 |
ENSMUST00000118206.1
|
2210404O07Rik
|
RIKEN cDNA 2210404O07 gene |
| chr13_-_13393592 | 2.96 |
ENSMUST00000021738.8
|
Gpr137b
|
G protein-coupled receptor 137B |
| chr2_-_91649751 | 2.95 |
ENSMUST00000099714.3
|
Zfp408
|
zinc finger protein 408 |
| chr11_+_87737530 | 2.93 |
ENSMUST00000093955.5
|
Supt4a
|
suppressor of Ty 4A |
| chr1_+_171682004 | 2.92 |
ENSMUST00000015499.7
ENSMUST00000068584.5 |
Cd48
|
CD48 antigen |
| chr11_+_120458093 | 2.88 |
ENSMUST00000058370.7
ENSMUST00000175970.1 ENSMUST00000176120.1 |
Ccdc137
|
coiled-coil domain containing 137 |
| chrX_-_136085206 | 2.81 |
ENSMUST00000138878.1
ENSMUST00000080929.6 |
Nxf3
|
nuclear RNA export factor 3 |
| chr2_+_164074122 | 2.77 |
ENSMUST00000018353.7
|
Stk4
|
serine/threonine kinase 4 |
| chr7_-_3845050 | 2.76 |
ENSMUST00000108615.3
ENSMUST00000119469.1 |
Pira2
|
paired-Ig-like receptor A2 |
| chrX_+_42149288 | 2.73 |
ENSMUST00000115073.2
ENSMUST00000115072.1 |
Stag2
|
stromal antigen 2 |
| chr2_-_26640230 | 2.69 |
ENSMUST00000181621.1
ENSMUST00000180659.1 |
Snhg7
|
small nucleolar RNA host gene (non-protein coding) 7 |
| chr2_+_112265809 | 2.69 |
ENSMUST00000110991.2
|
Slc12a6
|
solute carrier family 12, member 6 |
| chr19_+_10605625 | 2.67 |
ENSMUST00000025649.8
|
Ddb1
|
damage specific DNA binding protein 1 |
| chr17_-_35516780 | 2.61 |
ENSMUST00000160885.1
ENSMUST00000159009.1 ENSMUST00000161012.1 |
Tcf19
|
transcription factor 19 |
| chr4_+_109343029 | 2.60 |
ENSMUST00000030281.5
|
Eps15
|
epidermal growth factor receptor pathway substrate 15 |
| chr7_-_81345189 | 2.53 |
ENSMUST00000080813.4
|
Rps17
|
ribosomal protein S17 |
| chr15_+_39745926 | 2.53 |
ENSMUST00000022913.4
|
Dcstamp
|
dentrocyte expressed seven transmembrane protein |
| chr8_+_121127827 | 2.51 |
ENSMUST00000181609.1
|
Foxl1
|
forkhead box L1 |
| chr8_+_120488416 | 2.51 |
ENSMUST00000034279.9
|
Gse1
|
genetic suppressor element 1 |
| chr2_+_121358591 | 2.48 |
ENSMUST00000000317.6
ENSMUST00000129130.1 |
Ckmt1
|
creatine kinase, mitochondrial 1, ubiquitous |
| chr4_+_133176336 | 2.46 |
ENSMUST00000105912.1
|
Wasf2
|
WAS protein family, member 2 |
| chrX_+_42149534 | 2.43 |
ENSMUST00000127618.1
|
Stag2
|
stromal antigen 2 |
| chr12_+_98268626 | 2.42 |
ENSMUST00000075072.4
|
Gpr65
|
G-protein coupled receptor 65 |
| chr16_+_36934976 | 2.35 |
ENSMUST00000023531.8
|
Hcls1
|
hematopoietic cell specific Lyn substrate 1 |
| chr9_+_21526144 | 2.32 |
ENSMUST00000086361.5
ENSMUST00000179459.1 ENSMUST00000173769.2 |
AB124611
|
cDNA sequence AB124611 |
| chr7_-_47008397 | 2.29 |
ENSMUST00000061639.7
|
Spty2d1
|
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) |
| chr7_-_19118357 | 2.29 |
ENSMUST00000141380.1
|
Gm4969
|
predicted gene 4969 |
| chr18_+_15832772 | 2.28 |
ENSMUST00000079733.5
|
Gm10036
|
predicted gene 10036 |
| chr13_-_78199757 | 2.27 |
ENSMUST00000091458.6
|
Nr2f1
|
nuclear receptor subfamily 2, group F, member 1 |
| chr6_-_34955903 | 2.27 |
ENSMUST00000147169.1
|
2010107G12Rik
|
RIKEN cDNA 2010107G12 gene |
| chr7_-_127208423 | 2.24 |
ENSMUST00000120705.1
|
Tbc1d10b
|
TBC1 domain family, member 10b |
| chr19_+_6399746 | 2.22 |
ENSMUST00000113468.1
|
Rasgrp2
|
RAS, guanyl releasing protein 2 |
| chr13_+_102693522 | 2.21 |
ENSMUST00000022124.3
ENSMUST00000171267.1 ENSMUST00000167144.1 ENSMUST00000170878.1 |
Cd180
|
CD180 antigen |
| chr3_-_146839365 | 2.17 |
ENSMUST00000084614.3
|
Gm10288
|
predicted gene 10288 |
| chr4_+_124714776 | 2.10 |
ENSMUST00000030734.4
|
Sf3a3
|
splicing factor 3a, subunit 3 |
| chr3_-_123672321 | 2.08 |
ENSMUST00000172537.1
ENSMUST00000029602.6 |
Ndst3
|
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 |
| chr17_-_13052280 | 2.04 |
ENSMUST00000091648.2
|
Gpr31b
|
G protein-coupled receptor 31, D17Leh66b region |
| chr3_-_90052463 | 2.03 |
ENSMUST00000029553.9
ENSMUST00000064639.8 ENSMUST00000090908.6 |
Ubap2l
|
ubiquitin associated protein 2-like |
| chr8_-_106573461 | 2.03 |
ENSMUST00000073722.5
|
Gm10073
|
predicted pseudogene 10073 |
| chr14_+_60378242 | 2.00 |
ENSMUST00000022561.6
|
Amer2
|
APC membrane recruitment 2 |
| chr11_-_77188968 | 2.00 |
ENSMUST00000108400.1
|
Efcab5
|
EF-hand calcium binding domain 5 |
| chr15_-_99705490 | 1.92 |
ENSMUST00000163472.2
|
Gm17349
|
predicted gene, 17349 |
| chr4_+_62663620 | 1.91 |
ENSMUST00000126338.1
|
Rgs3
|
regulator of G-protein signaling 3 |
| chr5_-_25498702 | 1.89 |
ENSMUST00000173073.1
ENSMUST00000045291.7 |
Kmt2c
|
lysine (K)-specific methyltransferase 2C |
| chr8_+_94923687 | 1.87 |
ENSMUST00000153448.1
ENSMUST00000074570.3 ENSMUST00000166802.1 |
Gpr114
|
G protein-coupled receptor 114 |
| chr6_+_122952515 | 1.85 |
ENSMUST00000117173.1
ENSMUST00000088468.4 |
Clec4a3
|
C-type lectin domain family 4, member a3 |
| chrX_-_94123359 | 1.80 |
ENSMUST00000137853.1
ENSMUST00000088102.5 ENSMUST00000113927.1 |
Zfx
|
zinc finger protein X-linked |
| chr7_-_45896656 | 1.78 |
ENSMUST00000120299.1
|
Syngr4
|
synaptogyrin 4 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Spib
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.7 | 23.1 | GO:0030221 | basophil differentiation(GO:0030221) |
| 6.6 | 19.7 | GO:0002277 | myeloid dendritic cell activation involved in immune response(GO:0002277) |
| 4.6 | 27.5 | GO:0032796 | uropod organization(GO:0032796) |
| 4.4 | 13.2 | GO:0045660 | positive regulation of neutrophil differentiation(GO:0045660) |
| 4.1 | 12.2 | GO:0070947 | neutrophil mediated killing of fungus(GO:0070947) |
| 3.5 | 17.6 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
| 3.3 | 9.8 | GO:0042231 | interleukin-10 biosynthetic process(GO:0042091) interleukin-13 biosynthetic process(GO:0042231) regulation of interleukin-10 biosynthetic process(GO:0045074) positive regulation of interleukin-4 biosynthetic process(GO:0045404) |
| 3.2 | 32.1 | GO:0030886 | negative regulation of myeloid dendritic cell activation(GO:0030886) |
| 3.2 | 12.8 | GO:0034241 | positive regulation of macrophage fusion(GO:0034241) |
| 3.0 | 8.9 | GO:2000458 | immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458) |
| 2.9 | 11.4 | GO:0002540 | leukotriene production involved in inflammatory response(GO:0002540) |
| 2.8 | 14.2 | GO:0070560 | negative regulation of inositol phosphate biosynthetic process(GO:0010920) protein secretion by platelet(GO:0070560) |
| 2.8 | 17.1 | GO:0070945 | neutrophil mediated killing of gram-negative bacterium(GO:0070945) |
| 2.7 | 10.9 | GO:0001803 | type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) |
| 2.7 | 8.0 | GO:0002644 | negative regulation of tolerance induction(GO:0002644) |
| 2.6 | 7.7 | GO:0071921 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
| 2.5 | 7.5 | GO:0010387 | COP9 signalosome assembly(GO:0010387) |
| 2.5 | 17.5 | GO:0010897 | negative regulation of triglyceride catabolic process(GO:0010897) |
| 2.2 | 8.8 | GO:0045659 | negative regulation of neutrophil differentiation(GO:0045659) |
| 2.0 | 10.2 | GO:0051902 | negative regulation of mitochondrial depolarization(GO:0051902) |
| 2.0 | 6.0 | GO:2000040 | dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) |
| 2.0 | 15.8 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 1.9 | 11.7 | GO:0032439 | endosome localization(GO:0032439) negative regulation of vacuolar transport(GO:1903336) |
| 1.8 | 5.5 | GO:1900149 | positive regulation of Schwann cell migration(GO:1900149) |
| 1.7 | 6.6 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 1.6 | 4.9 | GO:0014718 | positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) G1 to G0 transition involved in cell differentiation(GO:0070315) |
| 1.6 | 6.6 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 1.5 | 9.0 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
| 1.5 | 4.4 | GO:2000872 | positive regulation of progesterone secretion(GO:2000872) |
| 1.5 | 5.9 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 1.4 | 5.5 | GO:0033373 | protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382) |
| 1.4 | 4.1 | GO:1903972 | regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) |
| 1.3 | 6.7 | GO:0033277 | abortive mitotic cell cycle(GO:0033277) |
| 1.2 | 3.5 | GO:0051659 | positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470) maintenance of mitochondrion location(GO:0051659) relaxation of skeletal muscle(GO:0090076) |
| 1.2 | 3.5 | GO:1905051 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
| 1.1 | 3.4 | GO:0001812 | positive regulation of type I hypersensitivity(GO:0001812) |
| 1.1 | 3.4 | GO:0032741 | positive regulation of interleukin-18 production(GO:0032741) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165) |
| 1.1 | 5.6 | GO:2000622 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 1.1 | 8.9 | GO:0045046 | peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046) |
| 1.1 | 6.5 | GO:0002291 | T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291) |
| 1.0 | 14.6 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 1.0 | 11.0 | GO:0002361 | CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) |
| 1.0 | 3.9 | GO:0031296 | B cell costimulation(GO:0031296) |
| 0.9 | 8.4 | GO:0032074 | negative regulation of nuclease activity(GO:0032074) |
| 0.9 | 5.4 | GO:0051987 | positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) |
| 0.9 | 6.0 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
| 0.8 | 4.8 | GO:2000354 | regulation of ovarian follicle development(GO:2000354) |
| 0.8 | 4.8 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
| 0.8 | 4.7 | GO:0001866 | NK T cell proliferation(GO:0001866) |
| 0.8 | 2.3 | GO:0071477 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 0.8 | 6.2 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 0.7 | 6.6 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.7 | 3.5 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
| 0.7 | 2.8 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.7 | 4.1 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
| 0.7 | 2.7 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
| 0.6 | 3.8 | GO:0031394 | positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280) |
| 0.6 | 2.5 | GO:0061146 | Peyer's patch morphogenesis(GO:0061146) |
| 0.6 | 6.9 | GO:0035878 | nail development(GO:0035878) |
| 0.6 | 4.9 | GO:0001915 | negative regulation of T cell mediated cytotoxicity(GO:0001915) |
| 0.6 | 2.3 | GO:0010847 | regulation of chromatin assembly(GO:0010847) |
| 0.6 | 1.7 | GO:0003218 | cardiac left ventricle formation(GO:0003218) |
| 0.6 | 4.5 | GO:0032532 | regulation of microvillus length(GO:0032532) |
| 0.5 | 5.2 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.5 | 4.0 | GO:0051581 | negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612) |
| 0.5 | 18.1 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.5 | 3.3 | GO:1902410 | mitotic cytokinetic process(GO:1902410) |
| 0.5 | 25.7 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
| 0.4 | 5.5 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.4 | 4.7 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.4 | 2.1 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 0.3 | 1.7 | GO:2000435 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
| 0.3 | 2.1 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.3 | 14.5 | GO:0006779 | porphyrin-containing compound biosynthetic process(GO:0006779) |
| 0.3 | 1.4 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 0.3 | 2.4 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.3 | 1.9 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
| 0.3 | 0.9 | GO:2000793 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) cell proliferation involved in heart valve development(GO:2000793) |
| 0.3 | 7.9 | GO:0008340 | determination of adult lifespan(GO:0008340) |
| 0.3 | 5.7 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.3 | 1.6 | GO:0003105 | negative regulation of glomerular filtration(GO:0003105) |
| 0.3 | 2.6 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
| 0.3 | 5.9 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.2 | 0.7 | GO:0001928 | regulation of exocyst assembly(GO:0001928) |
| 0.2 | 1.2 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
| 0.2 | 2.0 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
| 0.2 | 2.9 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 0.2 | 2.8 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
| 0.2 | 6.9 | GO:0045954 | positive regulation of natural killer cell mediated cytotoxicity(GO:0045954) |
| 0.2 | 4.2 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.2 | 3.2 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.2 | 13.5 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.2 | 4.9 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.2 | 1.5 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
| 0.2 | 0.8 | GO:2001166 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
| 0.2 | 3.1 | GO:0009651 | response to salt stress(GO:0009651) |
| 0.1 | 2.5 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 0.1 | 2.3 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.1 | 2.8 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.1 | 3.2 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.1 | 0.8 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 0.1 | 7.2 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
| 0.1 | 3.1 | GO:0061029 | eyelid development in camera-type eye(GO:0061029) |
| 0.1 | 0.8 | GO:1905244 | regulation of modification of synaptic structure(GO:1905244) |
| 0.1 | 0.9 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 0.1 | 0.5 | GO:0002587 | negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587) |
| 0.1 | 0.4 | GO:0043686 | co-translational protein modification(GO:0043686) |
| 0.1 | 3.7 | GO:0002763 | positive regulation of myeloid leukocyte differentiation(GO:0002763) |
| 0.1 | 3.1 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.1 | 0.9 | GO:0086023 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) adrenergic receptor signaling pathway involved in heart process(GO:0086023) |
| 0.1 | 5.3 | GO:0048701 | embryonic cranial skeleton morphogenesis(GO:0048701) |
| 0.1 | 6.0 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.1 | 5.5 | GO:0070527 | platelet aggregation(GO:0070527) |
| 0.1 | 2.6 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
| 0.1 | 3.1 | GO:0043551 | regulation of phosphatidylinositol 3-kinase activity(GO:0043551) |
| 0.1 | 2.4 | GO:0010447 | response to acidic pH(GO:0010447) |
| 0.1 | 0.4 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 0.1 | 3.6 | GO:0070098 | chemokine-mediated signaling pathway(GO:0070098) |
| 0.1 | 0.5 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
| 0.1 | 0.9 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.1 | 0.2 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
| 0.1 | 1.5 | GO:0060746 | parental behavior(GO:0060746) |
| 0.1 | 0.4 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) germline stem cell asymmetric division(GO:0098728) |
| 0.1 | 1.1 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
| 0.1 | 0.5 | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) |
| 0.1 | 0.2 | GO:1901301 | pulmonary artery morphogenesis(GO:0061156) regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 0.1 | 7.2 | GO:0000910 | cytokinesis(GO:0000910) |
| 0.0 | 0.5 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
| 0.0 | 6.3 | GO:1903509 | liposaccharide metabolic process(GO:1903509) |
| 0.0 | 4.2 | GO:0032091 | negative regulation of protein binding(GO:0032091) |
| 0.0 | 14.0 | GO:0019221 | cytokine-mediated signaling pathway(GO:0019221) |
| 0.0 | 1.3 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 1.8 | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) |
| 0.0 | 0.2 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
| 0.0 | 0.4 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.0 | 5.0 | GO:0016579 | protein deubiquitination(GO:0016579) |
| 0.0 | 7.6 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
| 0.0 | 7.1 | GO:0032496 | response to lipopolysaccharide(GO:0032496) |
| 0.0 | 0.6 | GO:0043586 | tongue development(GO:0043586) |
| 0.0 | 0.1 | GO:0014735 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) regulation of muscle atrophy(GO:0014735) |
| 0.0 | 4.8 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
| 0.0 | 1.5 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.0 | 2.0 | GO:0090090 | negative regulation of canonical Wnt signaling pathway(GO:0090090) |
| 0.0 | 3.1 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 1.0 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 1.6 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.0 | 0.5 | GO:0045761 | regulation of adenylate cyclase activity(GO:0045761) |
| 0.0 | 0.1 | GO:0070253 | somatostatin secretion(GO:0070253) |
| 0.0 | 0.1 | GO:0071910 | determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910) |
| 0.0 | 0.3 | GO:0060008 | Sertoli cell differentiation(GO:0060008) |
| 0.0 | 0.5 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.2 | 20.6 | GO:0005944 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) |
| 2.4 | 14.5 | GO:0032437 | cuticular plate(GO:0032437) |
| 2.0 | 5.9 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 1.9 | 11.7 | GO:0097443 | sorting endosome(GO:0097443) |
| 1.5 | 12.4 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 1.5 | 24.3 | GO:0042581 | specific granule(GO:0042581) |
| 1.2 | 27.5 | GO:0032426 | stereocilium tip(GO:0032426) |
| 1.1 | 12.2 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.9 | 2.8 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
| 0.9 | 3.4 | GO:0036019 | endolysosome(GO:0036019) |
| 0.9 | 7.7 | GO:0008278 | cohesin complex(GO:0008278) |
| 0.8 | 13.2 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.7 | 6.7 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.7 | 9.1 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.7 | 6.5 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.6 | 4.8 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.6 | 3.5 | GO:0031673 | H zone(GO:0031673) |
| 0.5 | 5.3 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 0.5 | 5.5 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.5 | 9.0 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.5 | 5.5 | GO:0060091 | kinocilium(GO:0060091) |
| 0.5 | 27.1 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.5 | 8.9 | GO:0051286 | cell tip(GO:0051286) |
| 0.4 | 5.4 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 0.4 | 2.7 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.3 | 1.3 | GO:0097450 | astrocyte end-foot(GO:0097450) |
| 0.3 | 7.9 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.3 | 4.5 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 0.3 | 9.3 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.3 | 3.1 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.2 | 24.8 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.2 | 11.5 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.2 | 5.6 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.2 | 2.6 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.2 | 3.8 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.2 | 6.9 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.1 | 17.9 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.1 | 5.1 | GO:0016592 | mediator complex(GO:0016592) |
| 0.1 | 9.6 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 4.5 | GO:0032420 | stereocilium(GO:0032420) |
| 0.1 | 19.8 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.1 | 2.8 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 4.9 | GO:0000786 | nucleosome(GO:0000786) |
| 0.1 | 0.8 | GO:0033503 | HULC complex(GO:0033503) |
| 0.1 | 9.8 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.1 | 4.9 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.1 | 0.8 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 0.1 | 0.9 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.1 | 5.5 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.1 | 31.3 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.1 | 0.4 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.1 | 1.6 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.1 | 10.9 | GO:0005884 | actin filament(GO:0005884) |
| 0.1 | 9.4 | GO:0000776 | kinetochore(GO:0000776) |
| 0.1 | 3.5 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
| 0.1 | 0.5 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 2.9 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.1 | 6.3 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 2.0 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 6.2 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 11.0 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.0 | 3.6 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 0.7 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 1.9 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 15.5 | GO:0005911 | cell-cell junction(GO:0005911) |
| 0.0 | 1.6 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 3.1 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 0.3 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.4 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.2 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) COPII vesicle coat(GO:0030127) |
| 0.0 | 1.1 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 2.8 | GO:0016324 | apical plasma membrane(GO:0016324) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.9 | 17.6 | GO:0005151 | interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353) |
| 3.8 | 11.4 | GO:0004051 | arachidonate 5-lipoxygenase activity(GO:0004051) |
| 3.0 | 9.0 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 3.0 | 8.9 | GO:0035717 | chemokine (C-C motif) ligand 7 binding(GO:0035717) |
| 2.0 | 15.8 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 1.8 | 11.0 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 1.7 | 7.0 | GO:0019767 | IgE receptor activity(GO:0019767) |
| 1.6 | 17.5 | GO:0052813 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
| 1.5 | 8.8 | GO:0051425 | PTB domain binding(GO:0051425) |
| 1.4 | 23.1 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 1.4 | 4.1 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 1.4 | 12.2 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 1.3 | 18.8 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 1.2 | 27.5 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 1.2 | 3.5 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
| 1.1 | 8.9 | GO:0030911 | TPR domain binding(GO:0030911) |
| 0.8 | 6.7 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.8 | 2.3 | GO:0035827 | rubidium ion transmembrane transporter activity(GO:0035827) |
| 0.7 | 4.2 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.7 | 6.0 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.7 | 7.9 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.6 | 20.3 | GO:0008187 | poly-pyrimidine tract binding(GO:0008187) |
| 0.6 | 19.4 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.5 | 2.1 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) |
| 0.5 | 3.4 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 0.5 | 21.0 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.4 | 3.1 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.4 | 14.1 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.4 | 3.8 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.4 | 14.2 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.4 | 3.1 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 0.3 | 18.1 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.3 | 7.9 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.3 | 1.0 | GO:0016608 | growth hormone-releasing hormone activity(GO:0016608) |
| 0.3 | 4.8 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.3 | 4.9 | GO:0031432 | titin binding(GO:0031432) |
| 0.3 | 4.3 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.3 | 3.5 | GO:0005338 | nucleotide-sugar transmembrane transporter activity(GO:0005338) |
| 0.3 | 3.5 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.3 | 1.7 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 0.3 | 4.1 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.2 | 12.7 | GO:0016279 | lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279) |
| 0.2 | 5.7 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.2 | 0.8 | GO:0035851 | Krueppel-associated box domain binding(GO:0035851) |
| 0.2 | 21.3 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.2 | 2.1 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.2 | 17.1 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.2 | 0.9 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.2 | 2.3 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.1 | 4.9 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.1 | 5.3 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.1 | 4.4 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.1 | 4.5 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 5.9 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 4.2 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.1 | 0.3 | GO:0050429 | calcium-dependent phospholipase C activity(GO:0050429) |
| 0.1 | 3.6 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.1 | 37.1 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.1 | 2.3 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.1 | 18.3 | GO:0019903 | protein phosphatase binding(GO:0019903) |
| 0.1 | 2.7 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.1 | 4.3 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.1 | 1.4 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 0.9 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 4.3 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.1 | 4.2 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.1 | 32.0 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.1 | 7.6 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.1 | 3.6 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 5.5 | GO:0005518 | collagen binding(GO:0005518) |
| 0.1 | 2.8 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.1 | 6.6 | GO:0020037 | heme binding(GO:0020037) |
| 0.0 | 0.2 | GO:0016842 | amidine-lyase activity(GO:0016842) |
| 0.0 | 1.5 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 2.7 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.0 | 4.9 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 0.5 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 1.1 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.0 | 2.1 | GO:0004177 | aminopeptidase activity(GO:0004177) |
| 0.0 | 0.5 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.0 | 6.3 | GO:0052689 | carboxylic ester hydrolase activity(GO:0052689) |
| 0.0 | 2.3 | GO:0003823 | antigen binding(GO:0003823) |
| 0.0 | 0.9 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.0 | 4.2 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 1.3 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.0 | 0.4 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 4.5 | GO:0008168 | methyltransferase activity(GO:0008168) |
| 0.0 | 3.5 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
| 0.0 | 0.5 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) |
| 0.0 | 2.0 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 1.8 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 3.9 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.0 | 3.9 | GO:0019887 | protein kinase regulator activity(GO:0019887) |
| 0.0 | 1.0 | GO:0004004 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) |
| 0.0 | 0.9 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 0.7 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 6.7 | GO:0005509 | calcium ion binding(GO:0005509) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 7.1 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.8 | 39.0 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.4 | 8.2 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.4 | 14.7 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.4 | 30.4 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.4 | 34.7 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.4 | 21.4 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.3 | 24.9 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.3 | 4.8 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.3 | 11.7 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.2 | 21.7 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.2 | 5.7 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.2 | 9.8 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.2 | 13.5 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.2 | 7.9 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.2 | 8.7 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.2 | 9.7 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.2 | 4.2 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.1 | 7.9 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 3.6 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.1 | 5.5 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 9.8 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.1 | 5.9 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.1 | 1.9 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.1 | 5.2 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 0.7 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.1 | 0.4 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 0.9 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 0.7 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 3.1 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 6.4 | NABA CORE MATRISOME | Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans |
| 0.0 | 0.5 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 0.5 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.2 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 0.5 | PID FGF PATHWAY | FGF signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 8.9 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 1.0 | 12.4 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.8 | 14.3 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.8 | 3.8 | REACTOME ADP SIGNALLING THROUGH P2RY1 | Genes involved in ADP signalling through P2Y purinoceptor 1 |
| 0.7 | 3.4 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.6 | 30.4 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.6 | 24.8 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.6 | 4.8 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
| 0.5 | 7.9 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.5 | 5.7 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.5 | 6.7 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.5 | 6.5 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 0.5 | 9.0 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.4 | 4.3 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.4 | 7.1 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.3 | 4.1 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.3 | 4.3 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.3 | 14.5 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.3 | 15.4 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.3 | 5.8 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.3 | 3.5 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.3 | 18.0 | REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 0.3 | 2.4 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.3 | 51.2 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.3 | 20.5 | REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | Genes involved in Cell surface interactions at the vascular wall |
| 0.3 | 18.1 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.2 | 6.6 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.2 | 7.0 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.2 | 17.4 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.2 | 6.7 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.2 | 17.3 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.2 | 7.6 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.2 | 7.1 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.1 | 9.5 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
| 0.1 | 16.1 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.1 | 2.7 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.1 | 5.9 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 1.0 | REACTOME GLUCAGON TYPE LIGAND RECEPTORS | Genes involved in Glucagon-type ligand receptors |
| 0.1 | 6.6 | REACTOME INTEGRATION OF ENERGY METABOLISM | Genes involved in Integration of energy metabolism |
| 0.1 | 0.7 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.1 | 0.5 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.1 | 4.2 | REACTOME SIGNALING BY ERBB2 | Genes involved in Signaling by ERBB2 |
| 0.1 | 2.1 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 1.5 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.1 | 7.6 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 0.8 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 0.3 | REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
| 0.0 | 0.5 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
| 0.0 | 2.5 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 0.5 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 0.7 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.0 | 0.6 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.2 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 0.2 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 0.9 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |