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GSE58827: Dynamics of the Mouse Liver

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Results for Tbx20

Z-value: 0.39

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Transcription factors associated with Tbx20

Gene Symbol Gene ID Gene Info
Tbx20
ENSMUSG00000031965.8 T-box 20

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbx20mm10_v2_chr9_-_24774276_247743030.316.3e-02Click!

Activity profile of Tbx20 motif

Sorted Z-values of Tbx20 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_105933832 5.60 ENSMUST00000034368.6
Ctrl
chymotrypsin-like
chr7_+_79660196 1.89 ENSMUST00000035977.7
Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr5_-_53707532 1.48 ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chr4_-_118437331 1.15 ENSMUST00000006565.6
Cdc20
cell division cycle 20
chr19_+_38055002 1.01 ENSMUST00000096096.4
ENSMUST00000116506.1
ENSMUST00000169673.1
Cep55
centrosomal protein 55
chr12_+_51348265 0.77 ENSMUST00000119211.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr12_+_51348370 0.67 ENSMUST00000121521.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chrX_-_134751331 0.66 ENSMUST00000113194.1
ENSMUST00000052431.5
Armcx6
armadillo repeat containing, X-linked 6
chr17_-_29237759 0.59 ENSMUST00000137727.1
ENSMUST00000024805.7
Cpne5
copine V
chr5_-_120777628 0.39 ENSMUST00000044833.8
Oas3
2'-5' oligoadenylate synthetase 3
chr17_-_12868126 0.37 ENSMUST00000089015.3
Mas1
MAS1 oncogene
chr6_-_122340499 0.37 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr8_+_83900706 0.29 ENSMUST00000045393.8
ENSMUST00000132500.1
ENSMUST00000152978.1
Lphn1
latrophilin 1
chr15_+_75268379 0.25 ENSMUST00000023247.6
Ly6f
lymphocyte antigen 6 complex, locus F
chr8_-_22694061 0.21 ENSMUST00000131767.1
Ikbkb
inhibitor of kappaB kinase beta
chr6_-_122340525 0.17 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chr15_-_78495059 0.13 ENSMUST00000089398.1
Il2rb
interleukin 2 receptor, beta chain
chrX_+_99042581 0.10 ENSMUST00000036606.7
Stard8
START domain containing 8
chr7_-_105787544 0.10 ENSMUST00000078482.5
ENSMUST00000154659.1
Dchs1
dachsous 1 (Drosophila)
chr2_+_74681991 0.09 ENSMUST00000142312.1
Hoxd11
homeobox D11
chr1_+_24177610 0.08 ENSMUST00000054588.8
Col9a1
collagen, type IX, alpha 1
chr9_+_112227443 0.08 ENSMUST00000161216.1
2310075C17Rik
RIKEN cDNA 2310075C17 gene
chr11_-_61720795 0.06 ENSMUST00000051552.4
Slc5a10
solute carrier family 5 (sodium/glucose cotransporter), member 10
chr4_+_152116312 0.05 ENSMUST00000035275.7
Tnfrsf25
tumor necrosis factor receptor superfamily, member 25
chr8_-_85555261 0.02 ENSMUST00000034138.5
Dnaja2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr13_+_23011249 0.02 ENSMUST00000076897.1
Vmn1r213
vomeronasal 1 receptor 213

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx20

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.4 1.1 GO:0098763 mitotic cell cycle phase(GO:0098763)
0.2 1.9 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 1.0 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.4 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.4 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.6 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 1.4 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0090543 Flemming body(GO:0090543)
0.1 0.5 GO:0001739 sex chromatin(GO:0001739)
0.0 1.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.4 GO:0001595 angiotensin receptor activity(GO:0001595)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 5.6 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 1.5 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1