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GSE58827: Dynamics of the Mouse Liver

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Results for Tead1

Z-value: 0.80

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Transcription factors associated with Tead1

Gene Symbol Gene ID Gene Info
Tead1
ENSMUSG00000055320.10 TEA domain family member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tead1mm10_v2_chr7_+_112679327_1126793730.124.9e-01Click!

Activity profile of Tead1 motif

Sorted Z-values of Tead1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_125320633 4.35 ENSMUST00000176655.1
ENSMUST00000176110.1
Scnn1a
sodium channel, nonvoltage-gated 1 alpha
chr8_+_45627946 3.49 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chr16_+_43363855 3.35 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr6_-_98342728 3.10 ENSMUST00000164491.1
Gm765
predicted gene 765
chr8_-_47990535 3.08 ENSMUST00000057561.7
Wwc2
WW, C2 and coiled-coil domain containing 2
chr8_+_45627709 2.60 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2
sorbin and SH3 domain containing 2
chr10_+_28074813 2.36 ENSMUST00000166468.1
Ptprk
protein tyrosine phosphatase, receptor type, K
chr8_-_95306585 2.33 ENSMUST00000119870.2
ENSMUST00000093268.4
Cngb1
cyclic nucleotide gated channel beta 1
chr11_+_70700473 2.30 ENSMUST00000152618.2
ENSMUST00000102554.1
ENSMUST00000094499.4
ENSMUST00000072187.5
Kif1c
kinesin family member 1C
chr4_-_118544010 2.21 ENSMUST00000128098.1
Tmem125
transmembrane protein 125
chr11_+_70700606 2.07 ENSMUST00000137119.2
Kif1c
kinesin family member 1C
chr8_+_45628176 2.05 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr11_-_101170327 2.00 ENSMUST00000123864.1
Plekhh3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr19_-_4439388 1.98 ENSMUST00000117462.1
ENSMUST00000048197.3
Rhod
ras homolog gene family, member D
chr10_+_122448499 1.88 ENSMUST00000020323.5
Avpr1a
arginine vasopressin receptor 1A
chr6_+_88724667 1.87 ENSMUST00000163271.1
Mgll
monoglyceride lipase
chr19_-_42128982 1.83 ENSMUST00000161873.1
Avpi1
arginine vasopressin-induced 1
chr6_+_88724828 1.82 ENSMUST00000089449.2
Mgll
monoglyceride lipase
chr13_+_112464070 1.68 ENSMUST00000183663.1
ENSMUST00000184311.1
ENSMUST00000183886.1
Il6st
interleukin 6 signal transducer
chr4_+_43267165 1.59 ENSMUST00000107942.2
ENSMUST00000102953.3
Atp8b5
ATPase, class I, type 8B, member 5
chr19_-_42129043 1.59 ENSMUST00000018965.3
Avpi1
arginine vasopressin-induced 1
chr5_+_76951382 1.58 ENSMUST00000141687.1
Paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase
chr3_-_113258837 1.58 ENSMUST00000098673.3
Amy2a5
amylase 2a5
chr7_-_68264201 1.57 ENSMUST00000032770.2
Pgpep1l
pyroglutamyl-peptidase I-like
chr1_+_106171752 1.56 ENSMUST00000061047.6
Phlpp1
PH domain and leucine rich repeat protein phosphatase 1
chr17_+_86167777 1.55 ENSMUST00000097275.2
Prkce
protein kinase C, epsilon
chr1_+_4808237 1.55 ENSMUST00000131119.1
Lypla1
lysophospholipase 1
chr11_+_21239279 1.42 ENSMUST00000006221.7
ENSMUST00000109578.1
Vps54
vacuolar protein sorting 54 (yeast)
chr2_-_164857542 1.42 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
Pltp
phospholipid transfer protein
chr15_-_76009440 1.40 ENSMUST00000170153.1
Fam83h
family with sequence similarity 83, member H
chr17_-_28350600 1.36 ENSMUST00000114799.1
Tead3
TEA domain family member 3
chr14_-_122913751 1.34 ENSMUST00000160401.1
Ggact
gamma-glutamylamine cyclotransferase
chr10_+_93641041 1.33 ENSMUST00000020204.4
Ntn4
netrin 4
chr1_+_193301953 1.29 ENSMUST00000016315.9
Lamb3
laminin, beta 3
chr17_-_28350747 1.24 ENSMUST00000080572.7
ENSMUST00000156862.1
Tead3
TEA domain family member 3
chr14_-_61556746 1.23 ENSMUST00000100496.4
Spryd7
SPRY domain containing 7
chr4_+_62360695 1.22 ENSMUST00000084526.5
Slc31a1
solute carrier family 31, member 1
chr17_-_24209377 1.21 ENSMUST00000024931.4
Ntn3
netrin 3
chr14_-_122913085 1.20 ENSMUST00000162164.1
ENSMUST00000110679.2
ENSMUST00000038075.5
Ggact
gamma-glutamylamine cyclotransferase
chr5_+_76951307 1.19 ENSMUST00000031160.9
ENSMUST00000120912.1
ENSMUST00000117536.1
Paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase
chr9_-_96752822 1.18 ENSMUST00000152594.1
Zbtb38
zinc finger and BTB domain containing 38
chr7_+_141216626 1.18 ENSMUST00000141804.1
ENSMUST00000148975.1
Rassf7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr6_+_34598500 1.17 ENSMUST00000079391.3
ENSMUST00000142512.1
Cald1
caldesmon 1
chr17_+_3397189 1.17 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr2_+_91457501 1.13 ENSMUST00000028689.3
Lrp4
low density lipoprotein receptor-related protein 4
chr5_+_117363513 1.12 ENSMUST00000111959.1
Wsb2
WD repeat and SOCS box-containing 2
chr7_+_114745685 1.11 ENSMUST00000136645.1
ENSMUST00000169913.1
Insc
inscuteable homolog (Drosophila)
chr6_+_34598530 1.09 ENSMUST00000115027.1
ENSMUST00000115026.1
Cald1
caldesmon 1
chr4_+_149545102 1.09 ENSMUST00000105692.1
Ctnnbip1
catenin beta interacting protein 1
chr10_+_24595434 1.09 ENSMUST00000020171.5
Ctgf
connective tissue growth factor
chr2_+_55437100 1.06 ENSMUST00000112633.2
ENSMUST00000112632.1
Kcnj3
potassium inwardly-rectifying channel, subfamily J, member 3
chr16_+_43364145 1.04 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr14_-_54966925 1.00 ENSMUST00000111456.1
Myh6
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr19_-_57197377 1.00 ENSMUST00000111546.1
Ablim1
actin-binding LIM protein 1
chr13_-_34077992 0.99 ENSMUST00000056427.8
Tubb2a
tubulin, beta 2A class IIA
chr10_+_24595623 0.96 ENSMUST00000176228.1
ENSMUST00000129142.1
Ctgf
connective tissue growth factor
chr14_-_61556881 0.96 ENSMUST00000022497.8
Spryd7
SPRY domain containing 7
chr14_+_30879257 0.94 ENSMUST00000040715.6
Mustn1
musculoskeletal, embryonic nuclear protein 1
chr4_+_134065897 0.94 ENSMUST00000137053.1
Aim1l
absent in melanoma 1-like
chr3_-_57575760 0.92 ENSMUST00000029380.7
Wwtr1
WW domain containing transcription regulator 1
chr3_-_69127098 0.91 ENSMUST00000029353.2
Kpna4
karyopherin (importin) alpha 4
chr2_-_90580578 0.90 ENSMUST00000168621.2
Ptprj
protein tyrosine phosphatase, receptor type, J
chr11_+_77462605 0.89 ENSMUST00000130255.1
Coro6
coronin 6
chr5_+_24426831 0.87 ENSMUST00000155598.1
Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr6_-_115592571 0.87 ENSMUST00000112957.1
2510049J12Rik
RIKEN cDNA 2510049J12 gene
chr19_-_57197435 0.86 ENSMUST00000111550.1
Ablim1
actin-binding LIM protein 1
chr4_+_152297205 0.84 ENSMUST00000048892.7
Icmt
isoprenylcysteine carboxyl methyltransferase
chr6_+_146888481 0.82 ENSMUST00000016631.7
ENSMUST00000111623.2
Ppfibp1
PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr14_+_70577839 0.80 ENSMUST00000089049.2
Nudt18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr4_-_139968026 0.80 ENSMUST00000105031.2
Klhdc7a
kelch domain containing 7A
chr12_+_8973892 0.79 ENSMUST00000085745.6
ENSMUST00000111113.2
Wdr35
WD repeat domain 35
chr4_+_141278433 0.79 ENSMUST00000142429.1
Gm13056
predicted gene 13056
chrX_+_20848543 0.78 ENSMUST00000001155.4
ENSMUST00000122312.1
ENSMUST00000120356.1
ENSMUST00000122850.1
Araf
v-raf murine sarcoma 3611 viral oncogene homolog
chr6_-_134566913 0.76 ENSMUST00000032322.8
Lrp6
low density lipoprotein receptor-related protein 6
chr12_-_86988676 0.76 ENSMUST00000095521.2
Zdhhc22
zinc finger, DHHC-type containing 22
chr6_-_128124312 0.73 ENSMUST00000127105.1
Tspan9
tetraspanin 9
chr1_-_168432270 0.72 ENSMUST00000072863.4
Pbx1
pre B cell leukemia homeobox 1
chr12_-_98737405 0.72 ENSMUST00000170188.1
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr7_-_90129339 0.71 ENSMUST00000181189.1
2310010J17Rik
RIKEN cDNA 2310010J17 gene
chrX_+_152178945 0.69 ENSMUST00000096275.4
Iqsec2
IQ motif and Sec7 domain 2
chr19_-_57197496 0.68 ENSMUST00000111544.1
Ablim1
actin-binding LIM protein 1
chr11_-_5381734 0.64 ENSMUST00000172492.1
Znrf3
zinc and ring finger 3
chr2_+_20519776 0.61 ENSMUST00000114604.2
ENSMUST00000066509.3
Etl4
enhancer trap locus 4
chr6_+_113458765 0.60 ENSMUST00000101065.1
ENSMUST00000053569.4
Il17re
interleukin 17 receptor E
chr2_-_168230575 0.58 ENSMUST00000109193.1
Dpm1
dolichol-phosphate (beta-D) mannosyltransferase 1
chr9_-_96752653 0.58 ENSMUST00000062899.3
E030011O05Rik
RIKEN cDNA E030011O05 gene
chr7_-_65370908 0.57 ENSMUST00000032729.6
Tjp1
tight junction protein 1
chr6_+_87428986 0.57 ENSMUST00000032125.5
Bmp10
bone morphogenetic protein 10
chr2_+_91118136 0.55 ENSMUST00000169776.1
ENSMUST00000111430.3
ENSMUST00000137942.1
Mybpc3
myosin binding protein C, cardiac
chr13_-_74376566 0.55 ENSMUST00000091481.2
Zfp72
zinc finger protein 72
chr16_-_89508313 0.55 ENSMUST00000056118.2
Krtap7-1
keratin associated protein 7-1
chr9_+_102717668 0.54 ENSMUST00000035121.7
Amotl2
angiomotin-like 2
chr11_+_101984270 0.54 ENSMUST00000176722.1
ENSMUST00000175972.1
1700006E09Rik
RIKEN cDNA 1700006E09 gene
chr2_+_120404757 0.53 ENSMUST00000135074.1
Ganc
glucosidase, alpha; neutral C
chr5_-_30196418 0.52 ENSMUST00000125367.1
Gpr113
G protein-coupled receptor 113
chr9_-_8004585 0.50 ENSMUST00000086580.5
ENSMUST00000065353.6
Yap1
yes-associated protein 1
chr15_+_78842632 0.50 ENSMUST00000059619.1
Cdc42ep1
CDC42 effector protein (Rho GTPase binding) 1
chr11_+_77462325 0.48 ENSMUST00000102493.1
Coro6
coronin 6
chr2_+_19658055 0.48 ENSMUST00000052168.4
Otud1
OTU domain containing 1
chr8_-_105966038 0.47 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4
solute carrier family 12, member 4
chr16_+_91225550 0.45 ENSMUST00000035608.8
Olig2
oligodendrocyte transcription factor 2
chr18_-_9450097 0.45 ENSMUST00000053917.4
Ccny
cyclin Y
chr14_-_16575456 0.45 ENSMUST00000063750.6
Rarb
retinoic acid receptor, beta
chr14_-_54577578 0.44 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr4_-_115781012 0.44 ENSMUST00000106521.1
Tex38
testis expressed 38
chr9_+_107299152 0.40 ENSMUST00000171568.1
Cish
cytokine inducible SH2-containing protein
chr16_+_34651188 0.40 ENSMUST00000023530.4
Ropn1
ropporin, rhophilin associated protein 1
chr16_-_34262830 0.39 ENSMUST00000114947.1
Kalrn
kalirin, RhoGEF kinase
chr6_+_17306415 0.38 ENSMUST00000150901.1
Cav1
caveolin 1, caveolae protein
chr4_-_47057296 0.38 ENSMUST00000107747.1
ENSMUST00000084616.2
Anks6
ankyrin repeat and sterile alpha motif domain containing 6
chr6_-_99632376 0.37 ENSMUST00000176255.1
Gm20696
predicted gene 20696
chr6_+_17306335 0.36 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
Cav1
caveolin 1, caveolae protein
chr8_+_70302761 0.36 ENSMUST00000150968.1
Cope
coatomer protein complex, subunit epsilon
chr6_-_37442095 0.35 ENSMUST00000041093.5
Creb3l2
cAMP responsive element binding protein 3-like 2
chr5_+_31116702 0.35 ENSMUST00000013771.8
Trim54
tripartite motif-containing 54
chr4_-_103290853 0.35 ENSMUST00000168664.1
ENSMUST00000030245.3
ENSMUST00000097944.3
4921539E11Rik
RIKEN cDNA 4921539E11 gene
chr9_-_16378231 0.35 ENSMUST00000082170.5
Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr1_+_189728264 0.34 ENSMUST00000097442.2
Ptpn14
protein tyrosine phosphatase, non-receptor type 14
chr5_-_24601961 0.34 ENSMUST00000030791.7
Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr9_+_38752796 0.32 ENSMUST00000074740.2
Olfr920
olfactory receptor 920
chr9_+_102739648 0.30 ENSMUST00000178539.1
Gm5627
predicted gene 5627
chr4_+_45965327 0.30 ENSMUST00000107777.2
Tdrd7
tudor domain containing 7
chr9_-_44713196 0.30 ENSMUST00000144251.1
ENSMUST00000156918.1
Phldb1
pleckstrin homology-like domain, family B, member 1
chr16_-_34262945 0.29 ENSMUST00000114953.1
Kalrn
kalirin, RhoGEF kinase
chr11_-_60115226 0.29 ENSMUST00000130746.1
4930412M03Rik
RIKEN cDNA 4930412M03 gene
chr11_-_95225631 0.29 ENSMUST00000150818.1
Gm11515
predicted gene 11515
chr5_+_31116722 0.28 ENSMUST00000114637.1
Trim54
tripartite motif-containing 54
chr8_+_84415348 0.28 ENSMUST00000121390.1
ENSMUST00000122053.1
Cacna1a
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chrX_-_104413825 0.27 ENSMUST00000033695.5
Abcb7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr2_-_32775625 0.27 ENSMUST00000161958.1
Ttc16
tetratricopeptide repeat domain 16
chr6_-_134887783 0.26 ENSMUST00000066107.6
Gpr19
G protein-coupled receptor 19
chr8_+_70302518 0.24 ENSMUST00000066469.7
Cope
coatomer protein complex, subunit epsilon
chr19_+_22692613 0.24 ENSMUST00000099564.2
ENSMUST00000099566.3
Trpm3
transient receptor potential cation channel, subfamily M, member 3
chr4_+_15265798 0.24 ENSMUST00000062684.8
Tmem64
transmembrane protein 64
chr7_-_109616548 0.22 ENSMUST00000077909.1
ENSMUST00000084738.3
St5
suppression of tumorigenicity 5
chr6_+_145934113 0.22 ENSMUST00000032383.7
Sspn
sarcospan
chr3_+_89831352 0.21 ENSMUST00000050401.5
She
src homology 2 domain-containing transforming protein E
chr8_-_104310109 0.21 ENSMUST00000159039.1
Cmtm1
CKLF-like MARVEL transmembrane domain containing 1
chr19_+_44756049 0.21 ENSMUST00000174490.2
Pax2
paired box gene 2
chr4_-_62360524 0.20 ENSMUST00000107461.1
ENSMUST00000084528.3
Fkbp15
FK506 binding protein 15
chr13_+_65512678 0.18 ENSMUST00000081471.2
Gm10139
predicted gene 10139
chr11_+_120721452 0.18 ENSMUST00000018156.5
Rac3
RAS-related C3 botulinum substrate 3
chr9_-_65391652 0.16 ENSMUST00000068307.3
Kbtbd13
kelch repeat and BTB (POZ) domain containing 13
chr19_-_57197556 0.16 ENSMUST00000099294.2
Ablim1
actin-binding LIM protein 1
chr10_-_87493651 0.15 ENSMUST00000020243.7
Ascl1
achaete-scute complex homolog 1 (Drosophila)
chr9_-_107609215 0.12 ENSMUST00000102532.3
Sema3b
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr12_+_85746539 0.10 ENSMUST00000040461.3
Mfsd7c
major facilitator superfamily domain containing 7C
chr9_-_107609182 0.10 ENSMUST00000102531.1
Sema3b
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr1_-_3671498 0.08 ENSMUST00000070533.4
Xkr4
X Kell blood group precursor related family member 4
chr11_+_115974930 0.07 ENSMUST00000106460.2
Itgb4
integrin beta 4
chr4_+_115828061 0.07 ENSMUST00000030477.3
Mob3c
MOB kinase activator 3C
chr2_-_39190687 0.05 ENSMUST00000142872.1
ENSMUST00000038874.5
Scai
suppressor of cancer cell invasion
chrX_-_64276937 0.04 ENSMUST00000114679.1
ENSMUST00000069926.7
Slitrk4
SLIT and NTRK-like family, member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Tead1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.6 1.7 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.6 2.8 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.5 3.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.4 2.0 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.4 1.5 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.3 0.9 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.3 1.6 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.3 1.4 GO:0042360 vitamin E metabolic process(GO:0042360)
0.3 0.8 GO:0046710 GDP metabolic process(GO:0046710)
0.3 1.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.3 1.5 GO:0098734 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.3 0.8 GO:0061348 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.2 1.2 GO:0072719 cellular response to cisplatin(GO:0072719)
0.2 0.8 GO:0006481 C-terminal protein methylation(GO:0006481)
0.2 0.6 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 2.6 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 2.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.2 1.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.2 2.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.2 0.9 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.2 1.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.3 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 1.6 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 8.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.6 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1 0.6 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 5.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.6 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 1.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 4.3 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.1 0.6 GO:0019348 dolichol metabolic process(GO:0019348) GDP-mannose metabolic process(GO:0019673)
0.1 0.9 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 2.5 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.1 0.7 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 3.1 GO:0046621 negative regulation of organ growth(GO:0046621)
0.1 0.6 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 5.1 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.3 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 4.4 GO:0032760 positive regulation of tumor necrosis factor production(GO:0032760)
0.0 0.7 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 1.4 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 1.1 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.3 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 2.3 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 1.6 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.3 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.7 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.8 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.2 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 1.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.3 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:0010842 retina layer formation(GO:0010842)
0.0 0.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.3 1.3 GO:0005610 laminin-5 complex(GO:0005610)
0.3 2.3 GO:0030478 actin cap(GO:0030478)
0.2 1.4 GO:0000938 GARP complex(GO:0000938)
0.2 0.8 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.2 4.3 GO:0034706 sodium channel complex(GO:0034706)
0.2 0.5 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.6 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.4 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 0.6 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.8 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.1 GO:0016600 flotillin complex(GO:0016600)
0.1 1.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 2.0 GO:0043196 varicosity(GO:0043196)
0.1 0.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 4.4 GO:0005871 kinesin complex(GO:0005871)
0.0 4.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.4 GO:0045095 keratin filament(GO:0045095)
0.0 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 2.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 10.8 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.9 GO:0001772 immunological synapse(GO:0001772)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0004923 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.5 2.5 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.5 1.9 GO:0031893 vasopressin receptor binding(GO:0031893)
0.4 4.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.4 1.5 GO:0035276 ethanol binding(GO:0035276)
0.3 1.4 GO:1990254 keratin filament binding(GO:1990254)
0.3 0.8 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.3 0.8 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.2 3.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 1.6 GO:0004556 alpha-amylase activity(GO:0004556)
0.2 0.8 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.2 1.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 1.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.3 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.6 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 3.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 2.3 GO:0043855 cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.6 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.5 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.1 1.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 1.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 2.8 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 0.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 1.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.6 GO:0071253 connexin binding(GO:0071253)
0.1 0.6 GO:0031433 telethonin binding(GO:0031433)
0.1 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 2.4 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 4.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.7 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 1.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 0.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.7 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 2.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 4.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 5.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 2.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 1.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 3.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.9 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.4 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides