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GSE58827: Dynamics of the Mouse Liver

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Results for Tfap2c

Z-value: 1.68

Motif logo

Transcription factors associated with Tfap2c

Gene Symbol Gene ID Gene Info
ENSMUSG00000028640.5 transcription factor AP-2, gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfap2cmm10_v2_chr2_+_172550761_1725507820.582.4e-04Click!

Activity profile of Tfap2c motif

Sorted Z-values of Tfap2c motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_7268296 15.71 ENSMUST00000066646.4
REST corepressor 2
chr12_+_109459843 15.31 ENSMUST00000173812.1
delta-like 1 homolog (Drosophila)
chr12_-_76709997 12.08 ENSMUST00000166101.1
spectrin beta, erythrocytic
chrX_-_142306170 11.23 ENSMUST00000134825.2
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr5_+_33658123 11.01 ENSMUST00000074849.6
ENSMUST00000079534.4
transforming, acidic coiled-coil containing protein 3
chr2_-_170427828 9.29 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
breast carcinoma amplified sequence 1
chr8_+_105518736 9.06 ENSMUST00000034363.5
hydroxysteroid 11-beta dehydrogenase 2
chr17_+_48359891 8.93 ENSMUST00000024792.6
triggering receptor expressed on myeloid cells-like 1
chr9_+_65101453 8.14 ENSMUST00000077696.6
ENSMUST00000035499.4
ENSMUST00000166273.1
immunoglobulin superfamily, DCC subclass, member 4
chr8_+_84901928 7.70 ENSMUST00000067060.7
Kruppel-like factor 1 (erythroid)
chr17_+_56303321 7.52 ENSMUST00000001258.8
ubiquitin-like, containing PHD and RING finger domains, 1
chrX_-_7671341 7.14 ENSMUST00000033486.5
proteolipid protein 2
chr2_+_29869484 7.02 ENSMUST00000047521.6
ENSMUST00000134152.1
cerebral endothelial cell adhesion molecule
chr17_+_56303396 6.96 ENSMUST00000113038.1
ubiquitin-like, containing PHD and RING finger domains, 1
chr11_+_76998595 6.75 ENSMUST00000108402.2
ENSMUST00000021195.4
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
chr11_-_94474088 6.49 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr13_+_73467197 6.24 ENSMUST00000022099.8
lysophosphatidylcholine acyltransferase 1
chr2_+_103957976 6.24 ENSMUST00000156813.1
ENSMUST00000170926.1
LIM domain only 2
chr11_-_59964936 6.22 ENSMUST00000062405.7
RAS, dexamethasone-induced 1
chr7_-_126414855 6.09 ENSMUST00000032968.5
CD19 antigen
chr1_-_193201435 6.08 ENSMUST00000043550.4
TRAF3 interacting protein 3
chr2_-_29869785 6.06 ENSMUST00000047607.1
RIKEN cDNA 2600006K01 gene
chr2_-_32083783 6.05 ENSMUST00000056406.6
family with sequence similarity 78, member A
chr7_+_99535652 5.89 ENSMUST00000032995.8
ENSMUST00000162404.1
arrestin, beta 1
chr2_-_152415044 5.76 ENSMUST00000099207.3
zinc finger, CCHC domain containing 3
chr10_-_45470201 5.56 ENSMUST00000079390.6
lin-28 homolog B (C. elegans)
chr1_+_75479529 5.40 ENSMUST00000113575.2
ENSMUST00000148980.1
ENSMUST00000050899.6
transmembrane protein 198
chr2_-_34913976 5.36 ENSMUST00000028232.3
PHD finger protein 19
chr4_-_116464151 5.35 ENSMUST00000106486.1
ENSMUST00000106485.1
microtubule associated serine/threonine kinase 2
chr7_-_29518566 5.25 ENSMUST00000181975.1
signal-induced proliferation-associated 1 like 3
chr4_+_123282778 4.89 ENSMUST00000106243.1
ENSMUST00000106241.1
ENSMUST00000080178.6
poly(A) binding protein, cytoplasmic 4
chr2_+_91945703 4.69 ENSMUST00000178895.1
predicted gene 9821
chr7_+_30421724 4.68 ENSMUST00000108176.1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr4_+_135120640 4.51 ENSMUST00000056977.7
runt related transcription factor 3
chr2_-_160912292 4.47 ENSMUST00000109454.1
ENSMUST00000057169.4
elastin microfibril interfacer 3
chr2_-_32353247 4.24 ENSMUST00000078352.5
ENSMUST00000113352.2
ENSMUST00000113365.1
dynamin 1
chr7_+_25627604 4.20 ENSMUST00000076034.6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chrX_+_71962971 4.18 ENSMUST00000048790.6
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chrX_-_133688978 4.02 ENSMUST00000149154.1
ENSMUST00000167944.1
protocadherin 19
chr14_-_65262391 3.95 ENSMUST00000131309.1
frizzled homolog 3 (Drosophila)
chr1_-_75479271 3.91 ENSMUST00000079205.7
ENSMUST00000094818.2
chondroitin polymerizing factor
chr6_+_4504814 3.89 ENSMUST00000141483.1
collagen, type I, alpha 2
chr5_+_137758133 3.82 ENSMUST00000141733.1
ENSMUST00000110985.1
TSC22 domain family, member 4
chr10_-_127341583 3.80 ENSMUST00000026474.3
GLI-Kruppel family member GLI1
chr8_+_70493156 3.75 ENSMUST00000008032.7
cytokine receptor-like factor 1
chr4_+_111414959 3.74 ENSMUST00000030274.6
BEN domain containing 5
chr15_-_101712891 3.69 ENSMUST00000023709.5
keratin 5
chr6_-_83033422 3.60 ENSMUST00000089651.5
docking protein 1
chr13_-_49248146 3.58 ENSMUST00000119721.1
ENSMUST00000058196.6
sushi domain containing 3
chr3_-_88503187 3.38 ENSMUST00000120377.1
lamin A
chr6_+_88198656 3.37 ENSMUST00000015197.7
GATA binding protein 2
chr1_-_172027251 3.25 ENSMUST00000138714.1
vang-like 2 (van gogh, Drosophila)
chr6_-_28831747 3.25 ENSMUST00000062304.5
leucine rich repeat containing 4
chr7_-_4812351 3.24 ENSMUST00000079496.7
ubiquitin-conjugating enzyme E2S
chr11_+_61684419 3.24 ENSMUST00000093019.5
family with sequence similarity 83, member G
chr17_+_24473884 3.23 ENSMUST00000054946.3
ENSMUST00000164508.1
BRICHOS domain containing 5
chr11_-_120348475 3.23 ENSMUST00000062147.7
ENSMUST00000128055.1
actin, gamma, cytoplasmic 1
chr11_-_103356324 3.19 ENSMUST00000136491.2
ENSMUST00000107023.2
Rho GTPase activating protein 27
chr1_-_44061936 3.17 ENSMUST00000168641.1
predicted gene 8251
chr2_-_153529941 3.16 ENSMUST00000035346.7
RIKEN cDNA 8430427H17 gene
chr1_-_172027269 3.15 ENSMUST00000027837.6
ENSMUST00000111264.1
vang-like 2 (van gogh, Drosophila)
chr9_-_65391652 3.12 ENSMUST00000068307.3
kelch repeat and BTB (POZ) domain containing 13
chr1_-_75264195 3.08 ENSMUST00000027404.5
protein tyrosine phosphatase, receptor type, N
chr10_-_88379051 3.06 ENSMUST00000138159.1
DNA-damage regulated autophagy modulator 1
chr2_+_167062934 2.96 ENSMUST00000125674.1
RIKEN cDNA 1500012F01 gene
chr1_+_82839449 2.95 ENSMUST00000113444.1
ENSMUST00000063380.4
ArfGAP with FG repeats 1
chr4_+_104367549 2.93 ENSMUST00000106830.2
disabled 1
chr12_-_103242143 2.91 ENSMUST00000074416.3
proline rich membrane anchor 1
chr13_+_55445301 2.90 ENSMUST00000001115.8
ENSMUST00000099482.3
G protein-coupled receptor kinase 6
chr4_+_45203921 2.86 ENSMUST00000107804.1
FERM and PDZ domain containing 1
chr14_+_79451791 2.86 ENSMUST00000100359.1
kelch repeat and BTB (POZ) domain containing 6
chr11_+_3289880 2.82 ENSMUST00000110043.1
ENSMUST00000094471.3
POZ (BTB) and AT hook containing zinc finger 1
chr15_+_76457438 2.80 ENSMUST00000043089.7
scleraxis
chr3_-_88503331 2.79 ENSMUST00000029699.6
lamin A
chr2_+_76406529 2.78 ENSMUST00000111929.1
ENSMUST00000077972.4
ENSMUST00000111930.2
oxysterol binding protein-like 6
chr19_+_7417586 2.77 ENSMUST00000159348.1
RIKEN cDNA 2700081O15 gene
chrX_-_101085352 2.77 ENSMUST00000101362.1
ENSMUST00000073927.4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
chr8_+_122282117 2.76 ENSMUST00000054052.8
zinc finger protein, multitype 1
chr5_+_147430407 2.59 ENSMUST00000176600.1
PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr19_+_5068077 2.55 ENSMUST00000070630.6
CD248 antigen, endosialin
chr6_+_4505493 2.53 ENSMUST00000031668.8
collagen, type I, alpha 2
chr2_+_130274437 2.50 ENSMUST00000141872.1
NOP56 ribonucleoprotein
chrX_+_56447965 2.48 ENSMUST00000079663.6
predicted gene 2174
chr10_+_62252325 2.46 ENSMUST00000020278.5
tachykinin receptor 2
chr2_+_156421083 2.46 ENSMUST00000125153.2
ENSMUST00000103136.1
ENSMUST00000109577.2
erythrocyte protein band 4.1-like 1
chr17_+_35866606 2.43 ENSMUST00000113814.4
protein phosphatase 1, regulatory subunit 18
chr6_-_12749193 2.42 ENSMUST00000046121.6
ENSMUST00000172356.1
thrombospondin, type I, domain containing 7A
chr2_-_152398046 2.42 ENSMUST00000063332.8
ENSMUST00000182625.1
SRY-box containing gene 12
chr10_+_11281583 2.42 ENSMUST00000070300.4
F-box protein 30
chr2_+_156421048 2.39 ENSMUST00000109574.1
erythrocyte protein band 4.1-like 1
chr18_+_86394952 2.39 ENSMUST00000058829.2
neuropilin (NRP) and tolloid (TLL)-like 1
chr5_-_149051300 2.38 ENSMUST00000110505.1
high mobility group box 1
chr19_-_46039621 2.35 ENSMUST00000056931.7
LIM domain binding 1
chr14_-_24245913 2.35 ENSMUST00000073687.6
ENSMUST00000090398.4
discs, large homolog 5 (Drosophila)
chr11_-_78183551 2.34 ENSMUST00000102483.4
ribosomal protein L23A
chr9_-_105828085 2.31 ENSMUST00000166431.2
ENSMUST00000098441.3
collagen, type VI, alpha 6
chr5_-_35679416 2.30 ENSMUST00000114233.2
HtrA serine peptidase 3
chr4_-_136835843 2.29 ENSMUST00000105846.2
ENSMUST00000059287.7
ENSMUST00000105845.2
Eph receptor B2
chr6_+_38663061 2.26 ENSMUST00000114874.3
C-type lectin domain family 2, member L
chr2_+_156420837 2.24 ENSMUST00000103137.3
erythrocyte protein band 4.1-like 1
chr4_+_133480126 2.24 ENSMUST00000051676.6
family with sequence similarity 46, member B
chr19_-_7341433 2.24 ENSMUST00000165965.1
ENSMUST00000051711.9
ENSMUST00000169541.1
ENSMUST00000165989.1
MAP/microtubule affinity-regulating kinase 2
chr4_-_154636831 2.20 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
PR domain containing 16
chr7_+_127777095 2.12 ENSMUST00000144406.1
SET domain containing 1A
chr7_+_25221417 2.10 ENSMUST00000055604.4
zinc finger protein 526
chr10_+_11281304 2.07 ENSMUST00000129456.1
F-box protein 30
chr17_+_29660710 2.07 ENSMUST00000130423.1
cap methyltransferase 1
chr19_-_3929723 2.07 ENSMUST00000051803.6
aldehyde dehydrogenase 3 family, member B1
chr4_-_136602641 2.06 ENSMUST00000105847.1
ENSMUST00000116273.2
lysine (K)-specific demethylase 1A
chr2_+_130274424 2.01 ENSMUST00000103198.4
NOP56 ribonucleoprotein
chr13_-_23622502 2.01 ENSMUST00000062045.2
histone cluster 1, H1e
chr8_-_85067982 2.00 ENSMUST00000177563.1
predicted gene 5741
chr5_-_122989086 1.95 ENSMUST00000046073.9
lysine (K)-specific demethylase 2B
chr8_-_102785093 1.95 ENSMUST00000075190.3
cadherin 11
chr15_+_98634743 1.93 ENSMUST00000003442.7
calcium channel, voltage-dependent, beta 3 subunit
chr3_+_59006978 1.92 ENSMUST00000040325.7
ENSMUST00000164225.1
ENSMUST00000040846.8
ENSMUST00000029393.8
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)-like
chr13_+_54371340 1.91 ENSMUST00000026985.8
complexin 2
chr11_+_3289168 1.90 ENSMUST00000134089.1
POZ (BTB) and AT hook containing zinc finger 1
chr4_+_40473130 1.89 ENSMUST00000179526.1
transmembrane protein 215
chr7_-_104390586 1.87 ENSMUST00000106828.1
tripartite motif-containing 30C
chr7_+_90130227 1.83 ENSMUST00000049537.7
phosphatidylinositol binding clathrin assembly protein
chr18_-_60848911 1.81 ENSMUST00000177172.1
ENSMUST00000175934.1
ENSMUST00000176630.1
Treacher Collins Franceschetti syndrome 1, homolog
chr5_-_122989260 1.81 ENSMUST00000118027.1
lysine (K)-specific demethylase 2B
chr7_-_19604444 1.80 ENSMUST00000086041.5
CLK4-associating serine/arginine rich protein
chr9_-_76567092 1.79 ENSMUST00000183437.1
family with sequence similarity 83, member B
chr4_+_131873608 1.77 ENSMUST00000053819.3
serine/arginine-rich splicing factor 4
chr11_-_69413675 1.74 ENSMUST00000094077.4
KDM1 lysine (K)-specific demethylase 6B
chr18_-_61036189 1.72 ENSMUST00000025521.8
caudal type homeobox 1
chr5_-_122900267 1.70 ENSMUST00000031435.7
lysine (K)-specific demethylase 2B
chrX_-_73824938 1.69 ENSMUST00000114438.2
ENSMUST00000002080.5
PDZ domain containing 4
chr8_-_87959560 1.66 ENSMUST00000109655.2
zinc finger protein 423
chr14_+_31251454 1.64 ENSMUST00000022458.4
Brca1 associated protein 1
chr5_+_139352607 1.57 ENSMUST00000031521.8
cytochrome P450, family 2, subfamily w, polypeptide 1
chr3_-_9610074 1.56 ENSMUST00000041124.7
zinc finger protein 704
chr2_+_119897212 1.54 ENSMUST00000046717.6
ENSMUST00000110774.1
ENSMUST00000110773.2
ENSMUST00000079934.5
ENSMUST00000156510.1
MAX gene associated
chr10_+_24223517 1.52 ENSMUST00000095784.2
monooxygenase, DBH-like 1
chr11_-_120990871 1.51 ENSMUST00000154483.1
casein kinase 1, delta
chr3_-_27710413 1.51 ENSMUST00000046157.4
fibronectin type III domain containing 3B
chr9_+_108002501 1.51 ENSMUST00000035214.4
ENSMUST00000175874.1
inositol hexaphosphate kinase 1
chr7_-_25788635 1.50 ENSMUST00000002677.4
ENSMUST00000085948.4
AXL receptor tyrosine kinase
chr5_+_144545883 1.48 ENSMUST00000071782.6
neuronal pentraxin 2
chr8_-_116732991 1.48 ENSMUST00000109102.2
chromodomain protein, Y chromosome-like 2
chr2_+_74704861 1.47 ENSMUST00000019749.3
homeobox D8
chr6_+_118066356 1.46 ENSMUST00000164960.1
RasGEF domain family, member 1A
chr6_-_42693087 1.45 ENSMUST00000121083.1
family with sequence similarity 115, member A
chr4_-_44711446 1.44 ENSMUST00000014174.7
paired box gene 5
chr2_+_74705145 1.42 ENSMUST00000074721.5
homeobox D8
chr5_-_147307264 1.41 ENSMUST00000031650.3
caudal type homeobox 2
chr3_-_61365951 1.41 ENSMUST00000066298.2
RIKEN cDNA B430305J03 gene
chr8_-_84687839 1.40 ENSMUST00000001975.4
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr4_-_120287349 1.40 ENSMUST00000102656.3
forkhead box O6
chr7_+_25282784 1.39 ENSMUST00000165239.1
capicua homolog (Drosophila)
chr15_+_76351288 1.37 ENSMUST00000161527.1
ENSMUST00000160853.1
MAF1 homolog (S. cerevisiae)
chr5_-_149051604 1.36 ENSMUST00000093196.4
high mobility group box 1
chr1_-_167466780 1.36 ENSMUST00000036643.4
leucine rich repeat containing 52
chr17_+_29660595 1.34 ENSMUST00000024816.6
cap methyltransferase 1
chrX_-_48034842 1.33 ENSMUST00000039026.7
apelin
chr18_-_6490808 1.31 ENSMUST00000028100.6
ENSMUST00000050542.5
enhancer of polycomb homolog 1 (Drosophila)
chr2_+_152736244 1.28 ENSMUST00000038368.8
ENSMUST00000109824.1
inhibitor of DNA binding 1
chr16_+_35154870 1.27 ENSMUST00000114913.1
adenylate cyclase 5
chr3_-_154597045 1.26 ENSMUST00000052774.1
ENSMUST00000170461.1
ENSMUST00000122976.1
tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
chr1_-_161788489 1.24 ENSMUST00000000834.2
Fas ligand (TNF superfamily, member 6)
chr18_+_74216118 1.22 ENSMUST00000025444.6
CXXC finger 1 (PHD domain)
chr11_-_69398226 1.20 ENSMUST00000050140.5
transmembrane protein 88
chr3_-_108086590 1.18 ENSMUST00000102638.1
ENSMUST00000102637.1
adenosine monophosphate deaminase 2
chr7_+_127777376 1.18 ENSMUST00000126761.1
ENSMUST00000047157.6
SET domain containing 1A
chr6_-_42693030 1.17 ENSMUST00000045140.4
family with sequence similarity 115, member A
chr11_-_65162904 1.16 ENSMUST00000093002.5
ENSMUST00000047463.8
Rho GTPase activating protein 44
chrX_+_71556874 1.14 ENSMUST00000123100.1
high mobility group box 3
chr2_-_157204483 1.14 ENSMUST00000029170.7
retinoblastoma-like 1 (p107)
chr2_+_3118335 1.14 ENSMUST00000115099.2
family with sequence similarity 171, member A1
chr15_-_36608959 1.09 ENSMUST00000001809.8
poly(A) binding protein, cytoplasmic 1
chr15_+_100761741 1.03 ENSMUST00000023776.6
solute carrier family 4 (anion exchanger), member 8
chr9_+_89909775 1.02 ENSMUST00000034912.4
ENSMUST00000034909.4
RAS protein-specific guanine nucleotide-releasing factor 1
chr17_+_35866056 1.01 ENSMUST00000122899.1
protein phosphatase 1, regulatory subunit 18
chr4_+_152338619 0.97 ENSMUST00000030775.5
ENSMUST00000164662.1
chromodomain helicase DNA binding protein 5
chr4_+_63215402 0.95 ENSMUST00000036300.6
collagen, type XXVII, alpha 1
chr5_-_124354671 0.93 ENSMUST00000031341.4
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr19_-_28680077 0.91 ENSMUST00000162022.1
ENSMUST00000112612.2
GLIS family zinc finger 3
chr4_-_142084221 0.91 ENSMUST00000036572.3
transmembrane protein 51
chr14_+_119138415 0.90 ENSMUST00000065904.3
heparan sulfate 6-O-sulfotransferase 3
chr5_-_131307848 0.89 ENSMUST00000086023.5
Williams-Beuren syndrome chromosome region 17 homolog (human)
chr13_-_112652295 0.89 ENSMUST00000099166.2
ENSMUST00000075748.5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr19_-_45998479 0.89 ENSMUST00000045396.7
RIKEN cDNA 9130011E15 gene
chr8_-_104631312 0.89 ENSMUST00000034351.6
Ras-related associated with diabetes
chr11_-_116110211 0.87 ENSMUST00000106441.1
ENSMUST00000021120.5
tripartite motif-containing 47
chr7_+_3290553 0.85 ENSMUST00000096744.5
myeloid-associated differentiation marker
chr11_-_120991039 0.85 ENSMUST00000070575.7
casein kinase 1, delta
chr16_+_17070220 0.82 ENSMUST00000141959.1
yippee-like 1 (Drosophila)
chr5_+_150952607 0.82 ENSMUST00000078856.6
klotho
chr19_+_5568002 0.81 ENSMUST00000096318.3
adaptor-related protein complex 5, beta 1 subunit
chr19_+_10041548 0.79 ENSMUST00000115995.2
fatty acid desaturase 3
chrX_+_163909132 0.78 ENSMUST00000033734.7
ENSMUST00000112294.2
adaptor-related protein complex 1, sigma 2 subunit
chr3_+_103914560 0.78 ENSMUST00000106806.1
rosbin, round spermatid basic protein 1
chr1_-_63114516 0.78 ENSMUST00000097718.2
INO80 complex subunit D
chr7_+_105736702 0.77 ENSMUST00000163389.1
ENSMUST00000136687.1
integrin linked kinase
chr2_+_165503787 0.77 ENSMUST00000029196.4
solute carrier family 2 (facilitated glucose transporter), member 10
chr12_-_81333129 0.76 ENSMUST00000085238.6
ENSMUST00000182208.1
solute carrier family 8 (sodium/calcium exchanger), member 3
chr11_+_102189620 0.74 ENSMUST00000070334.3
ENSMUST00000078975.7
glucose 6 phosphatase, catalytic, 3
chr8_+_105605220 0.73 ENSMUST00000043531.8
family with sequence similarity 65, member A

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2c

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.1 GO:0002017 regulation of blood volume by renal aldosterone(GO:0002017)
1.7 10.4 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
1.7 6.8 GO:0021941 negative regulation of cerebellar granule cell precursor proliferation(GO:0021941)
1.6 6.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
1.6 6.2 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
1.4 2.8 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
1.2 3.7 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
1.2 6.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.1 8.0 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
1.1 3.4 GO:0097309 cap1 mRNA methylation(GO:0097309)
1.1 5.5 GO:0021993 initiation of neural tube closure(GO:0021993)
1.1 5.4 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725)
1.1 4.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.0 5.9 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
1.0 14.5 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.9 3.8 GO:0060032 notochord regression(GO:0060032)
0.8 3.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.8 2.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.7 2.9 GO:0097477 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) lateral motor column neuron migration(GO:0097477)
0.7 2.9 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.7 1.3 GO:0051466 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.6 5.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.6 4.2 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.6 2.3 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.6 4.7 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.6 9.9 GO:0030953 astral microtubule organization(GO:0030953)
0.6 2.8 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.5 3.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.5 15.3 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.5 6.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.5 3.6 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.5 7.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.5 1.5 GO:0006589 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.5 0.5 GO:0033122 negative regulation of purine nucleotide catabolic process(GO:0033122)
0.5 2.5 GO:0070459 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) operant conditioning(GO:0035106) prolactin secretion(GO:0070459)
0.5 2.8 GO:0015819 lysine transport(GO:0015819) ornithine transport(GO:0015822)
0.4 6.5 GO:0043589 skin morphogenesis(GO:0043589)
0.4 1.6 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.4 6.1 GO:0006968 cellular defense response(GO:0006968)
0.4 1.6 GO:1901376 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.4 3.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.4 5.4 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.4 3.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.4 1.5 GO:0097350 neutrophil clearance(GO:0097350)
0.4 1.8 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) negative regulation of metalloendopeptidase activity(GO:1904684) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.3 2.3 GO:0035331 negative regulation of hippo signaling(GO:0035331) protein localization to adherens junction(GO:0071896)
0.3 3.3 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.3 1.2 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.3 2.6 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.3 2.0 GO:0016584 nucleosome positioning(GO:0016584)
0.3 2.3 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.3 1.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.3 12.1 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.3 1.3 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.2 1.2 GO:0035617 stress granule disassembly(GO:0035617)
0.2 6.2 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.2 1.2 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.2 3.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 3.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 3.3 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.2 0.7 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.2 1.8 GO:0014029 neural crest formation(GO:0014029)
0.2 0.9 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 1.7 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 1.4 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.2 0.6 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 0.9 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 1.9 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.2 1.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 2.5 GO:0060033 anatomical structure regression(GO:0060033)
0.2 0.5 GO:1903406 regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.2 1.0 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.2 1.5 GO:0006020 inositol metabolic process(GO:0006020)
0.2 0.9 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.4 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 2.9 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.6 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 2.2 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.1 1.2 GO:0032264 IMP salvage(GO:0032264)
0.1 4.5 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.1 1.9 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.1 4.5 GO:0000154 rRNA modification(GO:0000154)
0.1 0.7 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.8 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.1 4.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.4 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.5 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.1 1.5 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.1 2.2 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 0.4 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 2.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.1 11.2 GO:0030168 platelet activation(GO:0030168)
0.1 1.4 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 4.9 GO:0061515 myeloid cell development(GO:0061515)
0.1 0.4 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.6 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 1.0 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 1.4 GO:0021670 lateral ventricle development(GO:0021670)
0.1 0.2 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382) regulation of metaphase plate congression(GO:0090235)
0.1 0.3 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 1.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.5 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.2 GO:0007308 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.1 0.8 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 5.0 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.1 2.2 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 2.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.8 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 1.7 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.5 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.9 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.8 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 2.3 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 4.7 GO:0046546 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.9 GO:0060325 face morphogenesis(GO:0060325)
0.0 2.0 GO:0048286 lung alveolus development(GO:0048286)
0.0 1.1 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.2 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 2.3 GO:0008306 associative learning(GO:0008306)
0.0 1.7 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.4 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.9 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.8 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 2.4 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 1.0 GO:0051453 regulation of intracellular pH(GO:0051453)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0005584 collagen type I trimer(GO:0005584)
1.7 12.1 GO:0008091 spectrin(GO:0008091)
1.6 6.4 GO:0060187 cell pole(GO:0060187)
0.9 3.7 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.9 6.2 GO:0005638 lamin filament(GO:0005638)
0.9 2.6 GO:0031251 PAN complex(GO:0031251)
0.7 5.2 GO:0061689 tricellular tight junction(GO:0061689)
0.6 4.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.6 1.8 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.5 1.8 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.4 8.9 GO:0031091 platelet alpha granule(GO:0031091)
0.3 5.9 GO:0031143 pseudopodium(GO:0031143)
0.3 17.8 GO:0000791 euchromatin(GO:0000791)
0.3 3.8 GO:0097542 ciliary tip(GO:0097542)
0.3 1.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 2.2 GO:0097427 microtubule bundle(GO:0097427)
0.2 3.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 1.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 22.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 3.9 GO:0032433 filopodium tip(GO:0032433)
0.2 4.2 GO:0043196 varicosity(GO:0043196)
0.2 3.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 6.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.9 GO:0071547 piP-body(GO:0071547)
0.1 2.3 GO:0031932 TORC2 complex(GO:0031932)
0.1 3.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 5.7 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.6 GO:0070820 cytolytic granule(GO:0044194) tertiary granule(GO:0070820)
0.1 2.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.0 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 2.4 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 6.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 4.0 GO:0043034 costamere(GO:0043034)
0.1 6.2 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.1 7.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.5 GO:0033643 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.1 1.2 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 2.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.9 GO:0016592 mediator complex(GO:0016592)
0.0 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 14.3 GO:0014069 postsynaptic density(GO:0014069)
0.0 14.4 GO:0000790 nuclear chromatin(GO:0000790)
0.0 2.1 GO:0005876 spindle microtubule(GO:0005876)
0.0 15.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 2.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 2.4 GO:0032993 protein-DNA complex(GO:0032993)
0.0 2.1 GO:0043197 dendritic spine(GO:0043197)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.6 GO:0045095 keratin filament(GO:0045095)
0.0 0.5 GO:0005771 multivesicular body(GO:0005771)
0.0 9.4 GO:0005813 centrosome(GO:0005813)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 4.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.4 GO:0097610 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
2.4 14.5 GO:0031493 nucleosomal histone binding(GO:0031493)
2.3 6.8 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
2.1 6.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
2.0 5.9 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
1.6 6.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
1.4 4.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
1.3 3.9 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
1.2 3.7 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.9 1.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.9 3.4 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.8 2.5 GO:0004995 tachykinin receptor activity(GO:0004995)
0.8 8.0 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.7 2.9 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.7 3.3 GO:1990188 euchromatin binding(GO:1990188)
0.6 1.8 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.6 2.8 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) L-lysine transmembrane transporter activity(GO:0015189)
0.5 1.5 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.5 3.7 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.4 1.8 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.4 4.7 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.4 6.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.4 2.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.3 1.5 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.3 2.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.3 2.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.3 5.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.3 2.0 GO:0032564 dATP binding(GO:0032564)
0.3 7.1 GO:0019956 chemokine binding(GO:0019956)
0.3 4.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 1.4 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.3 5.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 0.7 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.2 1.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.2 6.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 2.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 0.9 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 1.3 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 0.8 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.2 0.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 2.3 GO:0030274 LIM domain binding(GO:0030274)
0.2 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 1.8 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 6.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 3.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 2.9 GO:0043495 protein anchor(GO:0043495)
0.2 9.0 GO:0070888 E-box binding(GO:0070888)
0.2 6.2 GO:0030506 ankyrin binding(GO:0030506)
0.2 0.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 3.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.4 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.1 2.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 4.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 12.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 1.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 5.3 GO:0035064 methylated histone binding(GO:0035064)
0.1 5.2 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 2.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 3.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 3.6 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.2 GO:0005123 death receptor binding(GO:0005123)
0.1 0.5 GO:0000293 ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 3.6 GO:0097110 scaffold protein binding(GO:0097110)
0.1 1.3 GO:0070628 proteasome binding(GO:0070628)
0.1 1.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 1.6 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 4.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0070878 primary miRNA binding(GO:0070878)
0.0 9.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 2.2 GO:0030507 spectrin binding(GO:0030507)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 3.1 GO:0046332 SMAD binding(GO:0046332)
0.0 1.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 3.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 7.3 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.8 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 1.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 8.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.6 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 1.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.9 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 10.9 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0 3.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 3.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.9 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 11.0 PID AURORA A PATHWAY Aurora A signaling
0.2 15.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 8.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.2 8.4 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.2 6.4 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 0.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 6.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 4.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 3.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 5.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 0.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 4.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 3.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 8.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 3.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 1.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 6.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 3.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.3 PID IL3 PATHWAY IL3-mediated signaling events
0.1 2.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 3.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 3.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.7 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.9 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 21.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.5 6.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 6.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.3 4.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.3 11.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 4.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 3.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.2 3.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 6.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 8.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 4.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 5.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 6.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 2.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 6.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.8 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 2.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 3.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.5 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation