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GSE58827: Dynamics of the Mouse Liver

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Results for Tlx2

Z-value: 0.63

Motif logo

Transcription factors associated with Tlx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000068327.3 T cell leukemia, homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tlx2mm10_v2_chr6_-_83070225_83070377-0.202.4e-01Click!

Activity profile of Tlx2 motif

Sorted Z-values of Tlx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_105933832 2.41 ENSMUST00000034368.6
chymotrypsin-like
chr7_-_30924169 2.18 ENSMUST00000074671.6
hepcidin antimicrobial peptide 2
chr1_-_150466165 1.98 ENSMUST00000162367.1
ENSMUST00000161611.1
ENSMUST00000161320.1
ENSMUST00000159035.1
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
chr8_-_111691002 1.94 ENSMUST00000034435.5
chymotrypsinogen B1
chr3_-_98630309 1.89 ENSMUST00000044094.4
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5
chr17_-_31144271 1.88 ENSMUST00000024826.7
trefoil factor 2 (spasmolytic protein 1)
chr8_+_105048592 1.74 ENSMUST00000093222.5
ENSMUST00000093223.3
carboxylesterase 3A
chr17_-_84682932 1.63 ENSMUST00000066175.3
ATP-binding cassette, sub-family G (WHITE), member 5
chr15_+_77729091 1.58 ENSMUST00000109775.2
apolipoprotein L 9b
chr5_+_137981512 1.48 ENSMUST00000035390.5
alpha-2-glycoprotein 1, zinc
chr4_-_60499332 1.47 ENSMUST00000135953.1
major urinary protein 1
chr19_-_7802578 1.46 ENSMUST00000120522.1
ENSMUST00000065634.7
solute carrier family 22 (organic cation transporter), member 26
chr17_+_84683113 1.39 ENSMUST00000045714.8
ATP-binding cassette, sub-family G (WHITE), member 8
chr1_-_162898665 1.38 ENSMUST00000111510.1
ENSMUST00000045902.6
flavin containing monooxygenase 2
chr17_+_84683131 1.37 ENSMUST00000171915.1
ATP-binding cassette, sub-family G (WHITE), member 8
chr4_+_63362443 1.36 ENSMUST00000075341.3
orosomucoid 2
chr18_+_60376029 1.31 ENSMUST00000066912.5
ENSMUST00000032473.6
interferon inducible GTPase 1
chr15_-_100687908 1.31 ENSMUST00000023775.7
chymotrypsin-like elastase family, member 1
chr13_-_55426783 1.29 ENSMUST00000021948.8
coagulation factor XII (Hageman factor)
chr5_-_145879857 1.21 ENSMUST00000035918.7
cytochrome P450, family 3, subfamily a, polypeptide 11
chr9_-_71168657 1.18 ENSMUST00000113570.1
aquaporin 9
chr11_+_115462464 1.15 ENSMUST00000106532.3
ENSMUST00000092445.5
ENSMUST00000153466.1
solute carrier family 16 (monocarboxylic acid transporters), member 5
chr9_+_111439063 1.11 ENSMUST00000111879.3
doublecortin-like kinase 3
chr5_-_105343929 1.04 ENSMUST00000183149.1
guanylate binding protein 11
chr13_+_23807027 1.03 ENSMUST00000006786.4
ENSMUST00000099697.2
solute carrier family 17 (sodium phosphate), member 2
chr1_-_139858684 1.03 ENSMUST00000094489.3
complement factor H-related 2
chr3_-_98753465 0.98 ENSMUST00000094050.4
ENSMUST00000090743.6
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
chr4_+_63356152 0.97 ENSMUST00000006687.4
orosomucoid 3
chr9_-_48605147 0.96 ENSMUST00000034808.5
ENSMUST00000119426.1
nicotinamide N-methyltransferase
chr6_-_21851914 0.94 ENSMUST00000134635.1
ENSMUST00000123116.1
ENSMUST00000120965.1
tetraspanin 12
chr13_-_55426769 0.93 ENSMUST00000170921.1
coagulation factor XII (Hageman factor)
chr2_+_25054396 0.88 ENSMUST00000102931.4
ENSMUST00000074422.7
ENSMUST00000132172.1
ENSMUST00000114388.1
ENSMUST00000114386.1
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr4_-_104876383 0.88 ENSMUST00000064873.8
ENSMUST00000106808.3
ENSMUST00000048947.8
complement component 8, alpha polypeptide
chr2_+_25054355 0.88 ENSMUST00000100334.4
ENSMUST00000152122.1
ENSMUST00000116574.3
ENSMUST00000006646.8
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr3_-_113574758 0.87 ENSMUST00000106540.1
amylase 1, salivary
chr18_+_20247340 0.87 ENSMUST00000054128.6
desmoglein 1 gamma
chr9_+_121642716 0.87 ENSMUST00000035115.4
vasoactive intestinal peptide receptor 1
chr4_-_141846277 0.83 ENSMUST00000105781.1
chymotrypsin C (caldecrin)
chr13_+_19342154 0.82 ENSMUST00000103566.3
T cell receptor gamma, constant 4
chr4_-_49506538 0.82 ENSMUST00000043056.2
bile acid-Coenzyme A: amino acid N-acyltransferase
chrX_+_20549780 0.81 ENSMUST00000023832.6
regucalcin
chr19_-_11266122 0.80 ENSMUST00000169159.1
membrane-spanning 4-domains, subfamily A, member 1
chr18_-_3337467 0.80 ENSMUST00000154135.1
cAMP responsive element modulator
chr6_-_124636085 0.79 ENSMUST00000068797.2
predicted gene 5077
chr4_-_141846359 0.78 ENSMUST00000037059.10
chymotrypsin C (caldecrin)
chr4_-_108071327 0.76 ENSMUST00000106701.1
sterol carrier protein 2, liver
chr9_-_103219823 0.75 ENSMUST00000168142.1
transferrin
chr12_-_98577940 0.75 ENSMUST00000110113.1
potassium channel, subfamily K, member 10
chr8_+_70083509 0.72 ENSMUST00000007738.9
hyaluronan and proteoglycan link protein 4
chrX_-_139782353 0.72 ENSMUST00000101217.3
ripply1 homolog (zebrafish)
chr10_-_115362191 0.70 ENSMUST00000092170.5
transmembrane protein 19
chr3_-_113574242 0.70 ENSMUST00000142505.2
amylase 1, salivary
chr18_-_34720269 0.70 ENSMUST00000025224.7
glial cell line derived neurotrophic factor family receptor alpha 3
chr2_+_23069057 0.67 ENSMUST00000114526.1
ENSMUST00000114529.2
acyl-Coenzyme A binding domain containing 5
chr1_-_182409020 0.65 ENSMUST00000097444.1
predicted gene 10517
chr6_+_122513583 0.65 ENSMUST00000032210.7
ENSMUST00000148517.1
microfibrillar associated protein 5
chr11_+_51763682 0.65 ENSMUST00000020653.5
SAR1 gene homolog B (S. cerevisiae)
chr18_-_3337614 0.64 ENSMUST00000150235.1
ENSMUST00000154470.1
cAMP responsive element modulator
chr14_-_61360395 0.64 ENSMUST00000022494.8
emopamil binding protein-like
chr1_+_132298606 0.64 ENSMUST00000046071.4
kelch domain containing 8A
chr14_+_52824340 0.64 ENSMUST00000103648.2
T cell receptor alpha variable 11D
chr15_+_75596645 0.63 ENSMUST00000023243.4
GPI-anchored HDL-binding protein 1
chr11_+_102041509 0.62 ENSMUST00000123895.1
ENSMUST00000017453.5
ENSMUST00000107163.2
ENSMUST00000107164.2
CD300 antigen like family member G
chr7_+_79273201 0.61 ENSMUST00000037315.6
abhydrolase domain containing 2
chr2_+_23069210 0.61 ENSMUST00000155602.1
acyl-Coenzyme A binding domain containing 5
chr18_-_3281036 0.60 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
cAMP responsive element modulator
chr16_+_38902305 0.60 ENSMUST00000023478.7
immunoglobulin superfamily, member 11
chr11_+_102836296 0.60 ENSMUST00000021302.8
ENSMUST00000107072.1
HIG1 domain family, member 1B
chr2_-_25493432 0.59 ENSMUST00000114245.1
lipocalin 12
chr9_-_21989427 0.59 ENSMUST00000045726.6
ral guanine nucleotide dissociation stimulator-like 3
chr18_-_3337539 0.58 ENSMUST00000142690.1
ENSMUST00000025069.4
ENSMUST00000082141.5
ENSMUST00000165086.1
ENSMUST00000149803.1
cAMP responsive element modulator
chr13_-_56548534 0.57 ENSMUST00000062806.4
leukocyte cell-derived chemotaxin 2
chr12_+_100779088 0.57 ENSMUST00000110069.1
RIKEN cDNA 9030617O03 gene
chr12_+_100779074 0.56 ENSMUST00000110073.1
ENSMUST00000110070.1
RIKEN cDNA 9030617O03 gene
chr2_-_172458596 0.56 ENSMUST00000099060.1
glucosaminyl (N-acetyl) transferase family member 7
chr17_-_36058371 0.56 ENSMUST00000113742.2
predicted gene 11127
chr16_+_20733104 0.54 ENSMUST00000115423.1
ENSMUST00000007171.6
chordin
chr19_+_45076105 0.54 ENSMUST00000026234.4
Kazal-type serine peptidase inhibitor domain 1
chr9_-_51328898 0.53 ENSMUST00000039959.4
RIKEN cDNA 1810046K07 gene
chr17_+_43667389 0.53 ENSMUST00000170988.1
cytochrome P450, family 39, subfamily a, polypeptide 1
chr7_-_30598863 0.53 ENSMUST00000108150.1
zinc finger and BTB domain containing 32
chr8_+_13037802 0.51 ENSMUST00000152034.1
ENSMUST00000128418.1
coagulation factor X
chrX_+_10252305 0.51 ENSMUST00000049910.6
ornithine transcarbamylase
chr10_+_127849917 0.50 ENSMUST00000077530.2
retinol dehydrogenase 19
chr11_-_21572193 0.50 ENSMUST00000102874.4
malate dehydrogenase 1, NAD (soluble)
chr6_-_35326123 0.50 ENSMUST00000051176.7
family with sequence similarity 180, member A
chr9_-_21927515 0.50 ENSMUST00000178988.1
ENSMUST00000046831.9
transmembrane protein 205
chrX_+_10252361 0.48 ENSMUST00000115528.2
ornithine transcarbamylase
chr3_+_121723515 0.48 ENSMUST00000029771.8
coagulation factor III
chr16_-_18413452 0.47 ENSMUST00000165430.1
ENSMUST00000147720.1
catechol-O-methyltransferase
chr18_-_60273267 0.47 ENSMUST00000090260.4
predicted gene 4841
chr9_+_108080436 0.45 ENSMUST00000035211.7
ENSMUST00000162886.1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr1_-_132139605 0.45 ENSMUST00000112362.2
cyclin-dependent kinase 18
chr2_+_30364262 0.45 ENSMUST00000142801.1
ENSMUST00000100214.3
family with sequence similarity 73, member B
chr9_-_50728067 0.45 ENSMUST00000117646.1
DIX domain containing 1
chr9_-_50727921 0.45 ENSMUST00000118707.1
ENSMUST00000034566.8
DIX domain containing 1
chrX_+_141475385 0.44 ENSMUST00000112931.1
ENSMUST00000112930.1
collagen, type IV, alpha 5
chr17_+_35439155 0.44 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
histocompatibility 2, Q region locus 7
chr12_+_41024329 0.44 ENSMUST00000134965.1
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr7_+_131410601 0.44 ENSMUST00000015829.7
ENSMUST00000117518.1
acyl-Coenzyme A dehydrogenase, short/branched chain
chr10_+_18845071 0.43 ENSMUST00000019998.7
PERP, TP53 apoptosis effector
chr6_-_23839137 0.43 ENSMUST00000166458.2
ENSMUST00000142913.2
ENSMUST00000115357.1
ENSMUST00000069074.7
ENSMUST00000115361.2
ENSMUST00000018122.7
ENSMUST00000115355.1
ENSMUST00000115356.2
Ca2+-dependent activator protein for secretion 2
chr14_-_66868572 0.43 ENSMUST00000022629.8
dihydropyrimidinase-like 2
chr10_+_13966268 0.43 ENSMUST00000015645.4
human immunodeficiency virus type I enhancer binding protein 2
chr17_+_34263209 0.43 ENSMUST00000040828.5
histocompatibility 2, class II antigen A, beta 1
chr11_-_4160286 0.42 ENSMUST00000093381.4
ENSMUST00000101626.2
coiled-coil domain containing 157
chr9_+_44107268 0.42 ENSMUST00000114821.2
ENSMUST00000114818.2
C1q and tumor necrosis factor related protein 5
chr4_+_134396320 0.42 ENSMUST00000105869.2
platelet-activating factor acetylhydrolase 2
chr19_+_36554661 0.42 ENSMUST00000169036.2
ENSMUST00000047247.5
HECT domain containing 2
chr15_+_54745702 0.41 ENSMUST00000050027.8
nephroblastoma overexpressed gene
chr10_+_116301374 0.41 ENSMUST00000092167.5
protein tyrosine phosphatase, receptor type, B
chr3_-_101604580 0.41 ENSMUST00000036493.6
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr7_-_48456331 0.41 ENSMUST00000094384.3
MAS-related GPR, member B1
chr13_-_36734450 0.40 ENSMUST00000037623.8
neuritin 1
chr12_+_41024090 0.40 ENSMUST00000132121.1
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr2_+_34772089 0.40 ENSMUST00000028222.6
ENSMUST00000100171.2
heat shock protein 5
chr9_+_44107286 0.40 ENSMUST00000152956.1
ENSMUST00000114815.1
C1q and tumor necrosis factor related protein 5
chr6_+_117168535 0.40 ENSMUST00000112866.1
ENSMUST00000112871.1
ENSMUST00000073043.4
chemokine (C-X-C motif) ligand 12
chr16_+_43363855 0.39 ENSMUST00000156367.1
zinc finger and BTB domain containing 20
chr9_-_45204083 0.39 ENSMUST00000034599.8
transmembrane protease, serine 4
chr1_-_162859684 0.39 ENSMUST00000131058.1
flavin containing monooxygenase 1
chr6_+_122513643 0.39 ENSMUST00000118626.1
microfibrillar associated protein 5
chr4_-_41517326 0.39 ENSMUST00000030152.6
ENSMUST00000095126.4
RIKEN cDNA 1110017D15 gene
chr16_+_22892035 0.38 ENSMUST00000023583.5
alpha-2-HS-glycoprotein
chr18_+_60293372 0.38 ENSMUST00000171297.1
RIKEN cDNA F830016B08 gene
chr2_+_30364227 0.38 ENSMUST00000077977.7
ENSMUST00000140075.2
family with sequence similarity 73, member B
chr14_+_32028989 0.38 ENSMUST00000022460.4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr10_-_127121125 0.38 ENSMUST00000164259.1
ENSMUST00000080975.4
amplified in osteosarcoma
chr2_-_150362708 0.38 ENSMUST00000051153.5
RIKEN cDNA 3300002I08 gene
chr9_-_107710475 0.37 ENSMUST00000080560.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr16_-_45408955 0.37 ENSMUST00000163230.1
CD200 antigen
chr9_-_29412204 0.37 ENSMUST00000115237.1
neurotrimin
chr16_-_23029062 0.37 ENSMUST00000115349.2
kininogen 2
chr8_+_94472763 0.37 ENSMUST00000053085.5
NLR family, CARD domain containing 5
chr10_+_79890853 0.37 ENSMUST00000061653.7
complement factor D (adipsin)
chr10_-_86705485 0.37 ENSMUST00000020238.7
heat shock protein 90, beta (Grp94), member 1
chr8_+_46492789 0.36 ENSMUST00000110371.1
acyl-CoA synthetase long-chain family member 1
chr18_+_56432116 0.36 ENSMUST00000070166.5
GRAM domain containing 3
chr17_+_24850515 0.36 ENSMUST00000154363.1
ENSMUST00000169200.1
hydroxyacyl glutathione hydrolase
chr1_-_106759727 0.36 ENSMUST00000010049.4
3-ketodihydrosphingosine reductase
chr2_-_168741898 0.36 ENSMUST00000109176.1
ENSMUST00000178504.1
ATPase, class II, type 9A
chr15_+_32920723 0.36 ENSMUST00000022871.5
syndecan 2
chr11_+_6658510 0.35 ENSMUST00000045374.7
receptor (calcitonin) activity modifying protein 3
chr2_-_69342600 0.35 ENSMUST00000102709.1
ENSMUST00000102710.3
ENSMUST00000180142.1
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr9_+_21927471 0.35 ENSMUST00000170304.1
ENSMUST00000006403.6
coiled-coil domain containing 159
chr12_-_44210061 0.35 ENSMUST00000015049.3
DnaJ (Hsp40) homolog, subfamily B, member 9
chr16_-_23029080 0.35 ENSMUST00000100046.2
kininogen 2
chr18_+_20376723 0.34 ENSMUST00000076737.6
desmoglein 1 beta
chr16_-_23029012 0.34 ENSMUST00000039338.6
kininogen 2
chr2_+_177768044 0.34 ENSMUST00000108942.3
predicted gene 14322
chr5_-_86518578 0.34 ENSMUST00000134179.1
transmembrane protease, serine 11g
chr2_+_4717825 0.34 ENSMUST00000184139.1
ENSMUST00000115022.1
BEN domain containing 7
chr10_+_4710119 0.33 ENSMUST00000105588.1
ENSMUST00000105589.1
estrogen receptor 1 (alpha)
chr7_+_45617575 0.33 ENSMUST00000008605.5
fucosyltransferase 1
chr1_+_16688405 0.33 ENSMUST00000026881.4
lymphocyte antigen 96
chr17_-_56109775 0.33 ENSMUST00000002908.7
perilipin 4
chr4_-_120747248 0.33 ENSMUST00000030376.7
potassium voltage-gated channel, subfamily Q, member 4
chr7_-_44306903 0.32 ENSMUST00000004587.9
C-type lectin domain family 11, member a
chr19_+_4003334 0.32 ENSMUST00000025806.3
double C2, gamma
chr2_-_163419508 0.32 ENSMUST00000046908.3
oxidative stress responsive serine rich 1
chr11_-_110251736 0.32 ENSMUST00000044003.7
ATP-binding cassette, sub-family A (ABC1), member 6
chr2_-_130424242 0.32 ENSMUST00000089581.4
PC-esterase domain containing 1A
chr8_-_61760067 0.32 ENSMUST00000121493.1
palladin, cytoskeletal associated protein
chr5_+_28071356 0.32 ENSMUST00000059155.10
insulin induced gene 1
chr11_+_43474276 0.32 ENSMUST00000173002.1
ENSMUST00000057679.3
C1q and tumor necrosis factor related protein 2
chr5_+_114146525 0.31 ENSMUST00000102582.1
acetyl-Coenzyme A carboxylase beta
chr12_+_44269145 0.31 ENSMUST00000043082.8
patatin-like phospholipase domain containing 8
chr17_-_73950172 0.31 ENSMUST00000024866.4
xanthine dehydrogenase
chr10_+_94036001 0.31 ENSMUST00000020208.4
FYVE, RhoGEF and PH domain containing 6
chr9_-_58313189 0.31 ENSMUST00000061799.8
lysyl oxidase-like 1
chr9_-_71771535 0.30 ENSMUST00000122065.1
ENSMUST00000121322.1
ENSMUST00000072899.2
cingulin-like 1
chr19_-_24031006 0.30 ENSMUST00000096164.4
family with sequence similarity 189, member A2
chr9_+_44107226 0.30 ENSMUST00000114816.1
C1q and tumor necrosis factor related protein 5
chr17_+_24850484 0.30 ENSMUST00000118788.1
hydroxyacyl glutathione hydrolase
chr3_-_151749877 0.30 ENSMUST00000029671.7
interferon-induced protein 44
chr17_+_34240015 0.30 ENSMUST00000173764.1
histocompatibility 2, O region beta locus
chr9_+_124121534 0.30 ENSMUST00000111442.1
ENSMUST00000171499.2
chemokine (C-C motif) receptor 5
chr5_+_22550391 0.29 ENSMUST00000181374.1
ENSMUST00000181764.1
ENSMUST00000181209.1
RIKEN cDNA 6030443J06 gene
chr11_+_51650954 0.29 ENSMUST00000117859.1
ENSMUST00000064493.5
RIKEN cDNA D930048N14 gene
chr5_-_123141067 0.29 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
expressed sequence AI480526
chr1_+_4808237 0.29 ENSMUST00000131119.1
lysophospholipase 1
chr7_+_130774069 0.29 ENSMUST00000048453.5
BTB (POZ) domain containing 16
chr2_-_30205772 0.29 ENSMUST00000113662.1
cysteine conjugate-beta lyase 1
chr6_-_119330723 0.29 ENSMUST00000068351.7
leucine-rich repeats and transmembrane domains 2
chr6_-_119330668 0.29 ENSMUST00000112756.1
leucine-rich repeats and transmembrane domains 2
chr18_+_20310738 0.29 ENSMUST00000077146.3
desmoglein 1 alpha
chr2_-_30205794 0.28 ENSMUST00000113663.2
ENSMUST00000044038.3
cysteine conjugate-beta lyase 1
chr14_-_33447142 0.28 ENSMUST00000111944.3
ENSMUST00000022504.5
ENSMUST00000111945.2
mitogen-activated protein kinase 8
chr7_-_126897424 0.28 ENSMUST00000120007.1
transmembrane protein 219
chr15_+_54571358 0.28 ENSMUST00000025356.2
mal, T cell differentiation protein 2
chr14_+_65837302 0.28 ENSMUST00000022614.5
coiled-coil domain containing 25
chr7_+_25619404 0.28 ENSMUST00000077338.5
ENSMUST00000085953.3
ATP5S-like
chr5_-_91402905 0.27 ENSMUST00000121044.2
betacellulin, epidermal growth factor family member
chr5_-_62766153 0.27 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_+_50110186 0.27 ENSMUST00000166318.1
ENSMUST00000036236.8
ENSMUST00000036225.8
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr17_+_24850742 0.27 ENSMUST00000149716.2
hydroxyacyl glutathione hydrolase
chr7_-_128740471 0.27 ENSMUST00000119081.1
ENSMUST00000057557.7
MCM (minichromosome maintenance deficient) binding protein
chr17_+_24850654 0.27 ENSMUST00000130989.1
ENSMUST00000024974.9
hydroxyacyl glutathione hydrolase
chr4_-_155345696 0.27 ENSMUST00000103178.4
protein kinase C, zeta
chr7_-_45061706 0.27 ENSMUST00000107832.1
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Tlx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0045796 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
0.9 2.7 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.5 2.2 GO:0034757 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.4 1.7 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.3 1.0 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.3 1.2 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.3 0.8 GO:0061300 cerebellum vasculature development(GO:0061300)
0.3 1.3 GO:0051541 elastin metabolic process(GO:0051541)
0.2 1.7 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.2 2.0 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.2 1.4 GO:0072592 oxygen metabolic process(GO:0072592)
0.2 0.8 GO:1901896 L-ascorbic acid biosynthetic process(GO:0019853) positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.2 0.8 GO:0032379 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.2 1.3 GO:0030242 pexophagy(GO:0030242)
0.2 0.5 GO:0030573 bile acid catabolic process(GO:0030573)
0.2 0.3 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.2 0.6 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.2 0.5 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.1 0.4 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.1 0.4 GO:1990523 negative regulation of sensory perception of pain(GO:1904057) bone regeneration(GO:1990523)
0.1 0.4 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 1.5 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.1 0.6 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1 1.2 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.5 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 0.3 GO:2001293 fatty-acyl-CoA biosynthetic process(GO:0046949) malonyl-CoA metabolic process(GO:2001293)
0.1 0.4 GO:1903416 response to glycoside(GO:1903416)
0.1 0.4 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.8 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 0.5 GO:0090005 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.1 0.3 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157)
0.1 0.4 GO:0046618 drug export(GO:0046618)
0.1 0.3 GO:0097494 regulation of vesicle size(GO:0097494)
0.1 0.3 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 1.2 GO:0015747 urate transport(GO:0015747)
0.1 2.2 GO:0035634 response to stilbenoid(GO:0035634)
0.1 0.2 GO:0021998 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) positive regulation of cardiac ventricle development(GO:1904414)
0.1 0.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 1.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.2 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 0.4 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.3 GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.1 0.5 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.3 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.1 0.3 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.3 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.1 0.9 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.3 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.1 0.2 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.1 0.3 GO:0009115 xanthine catabolic process(GO:0009115)
0.1 0.4 GO:0021636 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 0.6 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.2 GO:0032470 positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470) maintenance of mitochondrion location(GO:0051659) relaxation of skeletal muscle(GO:0090076)
0.1 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.2 GO:0036233 glycine import(GO:0036233)
0.1 0.2 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.3 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.4 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 0.4 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.4 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.1 0.7 GO:0032570 response to progesterone(GO:0032570)
0.1 0.3 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 2.3 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.3 GO:1901317 regulation of sperm motility(GO:1901317)
0.0 0.3 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.4 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0007521 muscle cell fate determination(GO:0007521)
0.0 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.4 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.5 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.0 0.4 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 1.2 GO:0097435 fibril organization(GO:0097435)
0.0 0.7 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.0 0.8 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.3 GO:0031622 positive regulation of fever generation(GO:0031622) negative regulation of macrophage apoptotic process(GO:2000110)
0.0 2.8 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.3 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 1.7 GO:0006953 acute-phase response(GO:0006953)
0.0 0.3 GO:0030035 microspike assembly(GO:0030035)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.2 GO:0018992 germ-line sex determination(GO:0018992)
0.0 0.3 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.2 GO:0070253 somatostatin secretion(GO:0070253)
0.0 0.4 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.7 GO:0048485 sympathetic nervous system development(GO:0048485)
0.0 0.2 GO:0045423 granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0 0.4 GO:0071318 cellular response to ATP(GO:0071318)
0.0 1.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.4 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.4 GO:0002934 desmosome organization(GO:0002934)
0.0 0.2 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.0 0.1 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.0 0.1 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:1903059 regulation of protein lipidation(GO:1903059)
0.0 0.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.4 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.3 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.0 0.4 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.1 GO:2001025 positive regulation of response to drug(GO:2001025)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.1 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.2 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.0 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 1.8 GO:0007586 digestion(GO:0007586)
0.0 0.2 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.0 GO:0006296 base-excision repair, AP site formation(GO:0006285) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.1 GO:1903301 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.0 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.4 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.7 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.2 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.3 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0015874 norepinephrine transport(GO:0015874)
0.0 0.4 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0015744 succinate transport(GO:0015744)
0.0 0.1 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.0 0.2 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 0.3 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.0 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.0 GO:0043056 forward locomotion(GO:0043056)
0.0 0.0 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.2 GO:0001967 suckling behavior(GO:0001967)
0.0 0.8 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.7 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.0 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.0 0.2 GO:0036065 fucosylation(GO:0036065)
0.0 1.0 GO:0035725 sodium ion transmembrane transport(GO:0035725)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3 0.8 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.3 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 0.8 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.9 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.8 GO:0097433 dense body(GO:0097433)
0.1 0.4 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.3 GO:1902636 kinociliary basal body(GO:1902636)
0.1 1.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 0.4 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.4 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.2 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 1.5 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 1.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0002177 manchette(GO:0002177)
0.0 0.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.8 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.6 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.4 GO:0072562 blood microparticle(GO:0072562)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0005009 insulin-activated receptor activity(GO:0005009) pheromone activity(GO:0005186)
0.3 1.0 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.2 1.0 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.2 1.2 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.2 1.6 GO:0004556 alpha-amylase activity(GO:0004556)
0.2 0.9 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.2 3.0 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 0.8 GO:1904121 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.2 1.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 2.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 0.5 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.2 4.1 GO:0017127 cholesterol transporter activity(GO:0017127)
0.2 0.5 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.2 1.2 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.1 1.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.3 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1 0.8 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.6 GO:0035473 lipase binding(GO:0035473)
0.1 1.5 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.4 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 0.3 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.4 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 2.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.5 GO:0045545 syndecan binding(GO:0045545)
0.1 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.3 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.3 GO:0016726 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.1 0.2 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 0.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.4 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.9 GO:0046977 TAP binding(GO:0046977)
0.1 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 0.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.8 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.1 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 11.4 GO:0017171 serine hydrolase activity(GO:0017171)
0.0 1.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.4 GO:0046790 virion binding(GO:0046790)
0.0 1.0 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.4 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 1.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.7 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391) steroid hormone binding(GO:1990239)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0097001 ceramide binding(GO:0097001)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 1.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.6 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 2.5 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.0 GO:0033265 choline binding(GO:0033265)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 1.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 2.8 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.2 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.9 GO:0008170 N-methyltransferase activity(GO:0008170)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.1 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 3.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.5 PID FOXO PATHWAY FoxO family signaling
0.0 0.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.1 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 2.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.5 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.0 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.0 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation