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GSE58827: Dynamics of the Mouse Liver

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Results for Zbtb12

Z-value: 0.78

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Transcription factors associated with Zbtb12

Gene Symbol Gene ID Gene Info
Zbtb12
ENSMUSG00000049823.8 zinc finger and BTB domain containing 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb12mm10_v2_chr17_+_34894515_34894573-0.702.5e-06Click!

Activity profile of Zbtb12 motif

Sorted Z-values of Zbtb12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_60921270 6.85 ENSMUST00000096418.3
A1bg
alpha-1-B glycoprotein
chr17_+_36942910 5.86 ENSMUST00000040498.5
Rnf39
ring finger protein 39
chr7_-_25539950 5.79 ENSMUST00000044547.8
Ceacam2
carcinoembryonic antigen-related cell adhesion molecule 2
chr7_-_25539845 5.79 ENSMUST00000066503.7
ENSMUST00000064862.6
Ceacam2
carcinoembryonic antigen-related cell adhesion molecule 2
chr17_+_36943025 5.27 ENSMUST00000173072.1
Rnf39
ring finger protein 39
chr7_-_48843663 4.68 ENSMUST00000167786.2
Csrp3
cysteine and glycine-rich protein 3
chr17_+_79626669 3.77 ENSMUST00000086570.1
4921513D11Rik
RIKEN cDNA 4921513D11 gene
chr7_-_25477607 3.14 ENSMUST00000098669.1
ENSMUST00000098668.1
ENSMUST00000098666.2
Ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr2_+_43555321 2.37 ENSMUST00000028223.2
Kynu
kynureninase (L-kynurenine hydrolase)
chr2_+_43555342 2.12 ENSMUST00000112826.1
ENSMUST00000050511.6
Kynu
kynureninase (L-kynurenine hydrolase)
chr18_-_46728342 2.12 ENSMUST00000035804.7
Cdo1
cysteine dioxygenase 1, cytosolic
chr5_+_95956916 2.11 ENSMUST00000023840.5
Cxcl13
chemokine (C-X-C motif) ligand 13
chr19_-_57182293 2.06 ENSMUST00000133369.1
Ablim1
actin-binding LIM protein 1
chr2_+_30364262 1.82 ENSMUST00000142801.1
ENSMUST00000100214.3
Fam73b
family with sequence similarity 73, member B
chr2_+_30364227 1.77 ENSMUST00000077977.7
ENSMUST00000140075.2
Fam73b
family with sequence similarity 73, member B
chr6_+_90462562 1.65 ENSMUST00000032174.5
Klf15
Kruppel-like factor 15
chr5_-_24447587 1.59 ENSMUST00000127194.1
ENSMUST00000115033.1
ENSMUST00000123167.1
ENSMUST00000030799.8
Tmub1
transmembrane and ubiquitin-like domain containing 1
chr4_-_45489794 1.54 ENSMUST00000146236.1
Shb
src homology 2 domain-containing transforming protein B
chr8_-_45382198 1.53 ENSMUST00000093526.6
Fam149a
family with sequence similarity 149, member A
chr7_+_101317073 1.46 ENSMUST00000163799.2
ENSMUST00000164479.2
Stard10
START domain containing 10
chr11_-_50916136 1.39 ENSMUST00000116378.1
ENSMUST00000109128.1
Zfp2
zinc finger protein 2
chr6_-_124814288 1.26 ENSMUST00000172132.2
Tpi1
triosephosphate isomerase 1
chr3_-_131344892 1.24 ENSMUST00000090246.4
ENSMUST00000126569.1
Sgms2
sphingomyelin synthase 2
chr7_+_140847801 1.16 ENSMUST00000026555.5
Odf3
outer dense fiber of sperm tails 3
chr15_-_88954400 1.10 ENSMUST00000109371.1
Ttll8
tubulin tyrosine ligase-like family, member 8
chr6_-_24528013 1.03 ENSMUST00000023851.5
Ndufa5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr17_-_32189457 1.02 ENSMUST00000087721.3
ENSMUST00000162117.1
Ephx3
epoxide hydrolase 3
chr15_-_82690499 0.98 ENSMUST00000100380.3
Cyp2d37-ps
cytochrome P450, family 2, subfamily d, polypeptide 37, pseudogene
chr4_-_119173849 0.98 ENSMUST00000052715.4
ENSMUST00000179290.1
ENSMUST00000154226.1
Zfp691
zinc finger protein 691
chr7_+_140847816 0.98 ENSMUST00000106049.1
Odf3
outer dense fiber of sperm tails 3
chr14_+_53845234 0.96 ENSMUST00000103674.4
Trav19
T cell receptor alpha variable 19
chr13_+_9276477 0.90 ENSMUST00000174552.1
Dip2c
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr2_+_109692436 0.89 ENSMUST00000111050.3
Bdnf
brain derived neurotrophic factor
chr16_-_94856682 0.78 ENSMUST00000165538.1
Kcnj6
potassium inwardly-rectifying channel, subfamily J, member 6
chr6_+_108065035 0.78 ENSMUST00000049246.6
Setmar
SET domain without mariner transposase fusion
chr4_-_138624001 0.77 ENSMUST00000030533.5
Vwa5b1
von Willebrand factor A domain containing 5B1
chr11_+_98446826 0.76 ENSMUST00000019456.4
Grb7
growth factor receptor bound protein 7
chr6_-_33060172 0.75 ENSMUST00000115091.1
ENSMUST00000127666.1
Chchd3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr11_+_108381164 0.75 ENSMUST00000146050.1
ENSMUST00000152958.1
Apoh
apolipoprotein H
chr6_-_143947061 0.70 ENSMUST00000124233.1
Sox5
SRY-box containing gene 5
chr10_-_75822521 0.69 ENSMUST00000160211.1
Gstt4
glutathione S-transferase, theta 4
chr2_-_150689360 0.63 ENSMUST00000046095.8
Vsx1
visual system homeobox 1 homolog (zebrafish)
chr3_+_5218516 0.62 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr3_+_5218546 0.62 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr7_+_100176663 0.61 ENSMUST00000178946.1
Kcne3
potassium voltage-gated channel, Isk-related subfamily, gene 3
chr9_+_36693217 0.61 ENSMUST00000034620.4
Acrv1
acrosomal vesicle protein 1
chr14_-_13914478 0.60 ENSMUST00000144914.1
Gm281
predicted gene 281
chr10_-_86011833 0.60 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc
BPI fold containing family C
chr2_-_28916668 0.58 ENSMUST00000113847.1
Barhl1
BarH-like 1 (Drosophila)
chr19_+_46573362 0.56 ENSMUST00000026011.6
Sfxn2
sideroflexin 2
chr9_+_18404418 0.54 ENSMUST00000164441.1
ENSMUST00000169398.1
Ubtfl1
upstream binding transcription factor, RNA polymerase I-like 1
chr4_+_43669266 0.52 ENSMUST00000107864.1
Tmem8b
transmembrane protein 8B
chr6_-_143947092 0.52 ENSMUST00000144289.1
ENSMUST00000111748.1
Sox5
SRY-box containing gene 5
chr13_-_92483996 0.52 ENSMUST00000040106.7
Fam151b
family with sequence similarity 151, member B
chr7_+_126976338 0.52 ENSMUST00000032920.3
Cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr4_-_133633419 0.51 ENSMUST00000084238.4
Zdhhc18
zinc finger, DHHC domain containing 18
chr17_-_15375969 0.49 ENSMUST00000014917.7
Dll1
delta-like 1 (Drosophila)
chr1_+_69826986 0.47 ENSMUST00000065425.5
ENSMUST00000113940.2
Spag16
sperm associated antigen 16
chr9_-_78481724 0.42 ENSMUST00000042235.8
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr11_+_48978889 0.40 ENSMUST00000179282.1
ENSMUST00000056759.4
Olfr56
olfactory receptor 56
chr3_-_40522909 0.39 ENSMUST00000035860.4
1700017G19Rik
RIKEN cDNA 1700017G19 gene
chr19_-_6080311 0.38 ENSMUST00000159832.1
Vps51
vacuolar protein sorting 51 homolog (S. cerevisiae)
chr15_-_99474696 0.37 ENSMUST00000040313.4
Bcdin3d
BCDIN3 domain containing
chr11_+_49050733 0.34 ENSMUST00000102785.1
Olfr56
olfactory receptor 56
chr13_+_76098734 0.34 ENSMUST00000091466.3
Ttc37
tetratricopeptide repeat domain 37
chr3_+_5218589 0.34 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr5_+_67260696 0.33 ENSMUST00000161233.1
ENSMUST00000160352.1
Tmem33
transmembrane protein 33
chr17_+_27029259 0.32 ENSMUST00000053683.6
Ggnbp1
gametogenetin binding protein 1
chr11_+_69991061 0.32 ENSMUST00000018711.8
Gabarap
gamma-aminobutyric acid receptor associated protein
chr5_+_10867186 0.30 ENSMUST00000168057.2
Gm6455
predicted gene 6455
chr14_-_59297510 0.30 ENSMUST00000062307.4
Phf11a
PHD finger protein 11A
chr4_+_119539716 0.30 ENSMUST00000137560.1
Foxj3
forkhead box J3
chr11_+_51085087 0.30 ENSMUST00000101255.1
9230009I02Rik
RIKEN cDNA 9230009I02 gene
chr5_+_11184207 0.29 ENSMUST00000168407.2
Gm5861
predicted gene 5861
chr12_+_105784694 0.29 ENSMUST00000109901.2
ENSMUST00000168186.1
ENSMUST00000163473.1
ENSMUST00000170540.1
ENSMUST00000166735.1
ENSMUST00000170002.1
Papola
poly (A) polymerase alpha
chr17_-_56874421 0.28 ENSMUST00000043062.4
Acsbg2
acyl-CoA synthetase bubblegum family member 2
chr15_-_76374926 0.28 ENSMUST00000071119.6
Tssk5
testis-specific serine kinase 5
chrX_-_140956675 0.26 ENSMUST00000033805.8
ENSMUST00000112978.1
Psmd10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr7_-_141918481 0.26 ENSMUST00000151890.1
Tollip
toll interacting protein
chr6_+_37900477 0.25 ENSMUST00000120238.1
Trim24
tripartite motif-containing 24
chr1_-_75232093 0.24 ENSMUST00000180101.1
A630095N17Rik
RIKEN cDNA A630095N17 gene
chr5_-_21865604 0.23 ENSMUST00000030878.1
Slc26a5
solute carrier family 26, member 5
chr6_+_24528144 0.22 ENSMUST00000031696.3
Asb15
ankyrin repeat and SOCS box-containing 15
chr17_-_33068035 0.22 ENSMUST00000024121.4
4921501E09Rik
RIKEN cDNA 4921501E09 gene
chrX_+_107792583 0.21 ENSMUST00000101292.2
Fam46d
family with sequence similarity 46, member D
chr5_+_92603039 0.21 ENSMUST00000050952.3
Stbd1
starch binding domain 1
chr1_+_37997975 0.20 ENSMUST00000027252.7
Eif5b
eukaryotic translation initiation factor 5B
chr8_+_129072644 0.20 ENSMUST00000148234.1
1700008F21Rik
RIKEN cDNA 1700008F21 gene
chr19_-_10240689 0.20 ENSMUST00000088013.5
Myrf
myelin regulatory factor
chr11_+_102885160 0.20 ENSMUST00000100369.3
Fam187a
family with sequence similarity 187, member A
chr5_+_30281377 0.18 ENSMUST00000101448.3
Drc1
dynein regulatory complex subunit 1
chr16_-_33967032 0.17 ENSMUST00000023510.6
Umps
uridine monophosphate synthetase
chr19_-_46573059 0.17 ENSMUST00000026009.8
Arl3
ADP-ribosylation factor-like 3
chr14_+_79481164 0.15 ENSMUST00000040131.5
Elf1
E74-like factor 1
chr8_+_40752208 0.14 ENSMUST00000096663.3
Adam25
a disintegrin and metallopeptidase domain 25 (testase 2)
chr9_+_110844497 0.14 ENSMUST00000176403.1
Prss46
protease, serine, 46
chrX_-_134476479 0.13 ENSMUST00000009740.2
Taf7l
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr17_-_27909206 0.13 ENSMUST00000114848.1
Taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr14_+_26693267 0.12 ENSMUST00000022433.4
Dnah12
dynein, axonemal, heavy chain 12
chr1_+_153891646 0.12 ENSMUST00000050660.4
Teddm1
transmembrane epididymal protein 1
chr4_-_41723129 0.11 ENSMUST00000171641.1
ENSMUST00000030158.4
Dctn3
dynactin 3
chr13_-_64497792 0.10 ENSMUST00000180282.1
1190003K10Rik
RIKEN cDNA 1190003K10 gene
chr3_-_84155762 0.08 ENSMUST00000047368.6
Mnd1
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr9_+_37367354 0.08 ENSMUST00000051839.7
Hepacam
hepatocyte cell adhesion molecule
chr10_+_63457505 0.06 ENSMUST00000105440.1
Ctnna3
catenin (cadherin associated protein), alpha 3
chr11_-_59079710 0.05 ENSMUST00000133040.1
Obscn
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr12_-_101958148 0.04 ENSMUST00000159883.1
ENSMUST00000160251.1
ENSMUST00000161011.1
ENSMUST00000021606.5
Atxn3
ataxin 3
chr17_+_27909337 0.02 ENSMUST00000114842.1
ENSMUST00000025058.7
ENSMUST00000088027.5
Anks1
ankyrin repeat and SAM domain containing 1
chr15_-_98898483 0.02 ENSMUST00000023737.4
Dhh
desert hedgehog
chrX_-_123029669 0.01 ENSMUST00000165345.1
Gm17521
predicted gene, 17521
chr2_+_130012336 0.01 ENSMUST00000110299.2
Tgm3
transglutaminase 3, E polypeptide
chr4_-_43669141 0.01 ENSMUST00000056474.6
Fam221b
family with sequence similarity 221, member B

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.6 GO:0070347 brown fat cell proliferation(GO:0070342) regulation of brown fat cell proliferation(GO:0070347)
1.6 4.7 GO:1903918 regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919)
1.5 4.5 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
1.0 3.1 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.7 2.1 GO:0046439 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.5 2.1 GO:2001027 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.4 1.3 GO:0046166 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.3 0.9 GO:0061193 taste bud development(GO:0061193)
0.2 0.5 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
0.2 1.1 GO:0018094 protein polyglycylation(GO:0018094)
0.2 1.5 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.2 0.5 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.2 1.5 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.2 0.6 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.2 1.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 1.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.7 GO:0034196 blood coagulation, intrinsic pathway(GO:0007597) acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.3 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.3 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.1 0.2 GO:0015755 fructose transport(GO:0015755)
0.1 1.6 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.2 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1 0.6 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.8 GO:0042407 cristae formation(GO:0042407)
0.0 0.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.8 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.8 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 1.0 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 2.1 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.4 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0 1.6 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.5 GO:0001832 blastocyst growth(GO:0001832)
0.0 0.3 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.3 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.4 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 14.2 GO:0042101 T cell receptor complex(GO:0042101)
0.2 2.1 GO:0001520 outer dense fiber(GO:0001520)
0.2 0.5 GO:1990716 axonemal central apparatus(GO:1990716)
0.1 0.3 GO:0055087 Ski complex(GO:0055087)
0.1 1.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.8 GO:0061617 MICOS complex(GO:0061617)
0.1 0.4 GO:1990745 EARP complex(GO:1990745)
0.0 0.9 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.7 GO:0042627 chylomicron(GO:0042627)
0.0 1.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.0 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 3.3 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.2 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.8 4.7 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.7 14.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.5 2.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.4 1.1 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.3 0.9 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.2 1.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 2.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.5 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.2 GO:2001069 glycogen binding(GO:2001069)
0.1 0.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.0 1.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.8 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 1.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 2.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.9 PID SHP2 PATHWAY SHP2 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport