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GSE58827: Dynamics of the Mouse Liver

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Results for Zbtb16

Z-value: 1.04

Motif logo

Transcription factors associated with Zbtb16

Gene Symbol Gene ID Gene Info
ENSMUSG00000066687.4 zinc finger and BTB domain containing 16

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb16mm10_v2_chr9_-_48835932_488359620.048.1e-01Click!

Activity profile of Zbtb16 motif

Sorted Z-values of Zbtb16 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_14492926 10.13 ENSMUST00000108524.3
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 7
chr1_-_150465563 9.68 ENSMUST00000164600.1
ENSMUST00000111902.2
ENSMUST00000111901.2
ENSMUST00000006171.9
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
chr1_-_150466165 9.66 ENSMUST00000162367.1
ENSMUST00000161611.1
ENSMUST00000161320.1
ENSMUST00000159035.1
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
chr4_-_61674094 7.90 ENSMUST00000098040.3
major urinary protein 18
chr1_-_139560158 5.10 ENSMUST00000160423.1
ENSMUST00000023965.5
complement factor H-related 1
chr11_-_5950018 4.97 ENSMUST00000102920.3
glucokinase
chr15_-_5063741 4.89 ENSMUST00000110689.3
complement component 7
chr8_-_93337195 4.05 ENSMUST00000044602.7
carboxylesterase 1G
chr7_-_14446570 3.91 ENSMUST00000063509.4
RIKEN cDNA 2810007J24 gene
chr4_-_108118504 3.86 ENSMUST00000149106.1
sterol carrier protein 2, liver
chr1_-_139858684 3.75 ENSMUST00000094489.3
complement factor H-related 2
chr12_-_103457195 3.72 ENSMUST00000044687.6
interferon, alpha-inducible protein 27 like 2B
chr1_+_127729405 3.52 ENSMUST00000038006.6
amino carboxymuconate semialdehyde decarboxylase
chr16_+_43510267 3.33 ENSMUST00000114695.2
zinc finger and BTB domain containing 20
chr4_-_108118528 3.19 ENSMUST00000030340.8
sterol carrier protein 2, liver
chr5_+_119671011 3.03 ENSMUST00000018748.8
T-box 3
chr10_+_63024512 2.94 ENSMUST00000020262.4
phenazine biosynthesis-like protein domain containing 2
chr19_-_8218832 2.86 ENSMUST00000113298.2
solute carrier family 22. member 29
chr6_-_129237948 2.83 ENSMUST00000181238.1
ENSMUST00000180379.1
RIKEN cDNA 2310001H17 gene
chr19_-_23075853 2.82 ENSMUST00000181623.1
RIKEN cDNA C330002G04 gene
chr5_-_139814025 2.79 ENSMUST00000146780.1
transmembrane protein 184a
chr9_+_119102463 2.47 ENSMUST00000140326.1
ENSMUST00000165231.1
deleted in lung and esophageal cancer 1
chr4_-_119383732 2.46 ENSMUST00000044781.2
ENSMUST00000084307.3
coiled-coil domain containing 30
chr7_+_141029131 2.43 ENSMUST00000170892.1
predicted gene, 17387
chr4_-_141846277 2.26 ENSMUST00000105781.1
chymotrypsin C (caldecrin)
chrX_-_75843063 2.24 ENSMUST00000114057.1
plastin 3 (T-isoform)
chr3_-_157925056 2.04 ENSMUST00000118539.1
cystathionase (cystathionine gamma-lyase)
chr3_-_113574242 2.03 ENSMUST00000142505.2
amylase 1, salivary
chr9_-_119157055 2.01 ENSMUST00000010795.4
acetyl-Coenzyme A acyltransferase 1B
chr18_-_3299537 1.99 ENSMUST00000129435.1
ENSMUST00000122958.1
cAMP responsive element modulator
chr5_-_139814231 1.97 ENSMUST00000044002.4
transmembrane protein 184a
chr5_+_114923234 1.91 ENSMUST00000031540.4
ENSMUST00000112143.3
2'-5' oligoadenylate synthetase-like 1
chr19_-_40187277 1.86 ENSMUST00000051846.6
cytochrome P450, family 2, subfamily c, polypeptide 70
chr4_-_19922599 1.79 ENSMUST00000029900.5
ATPase, H+ transporting, lysosomal V0 subunit D2
chr19_-_30175414 1.74 ENSMUST00000025778.7
glycine decarboxylase
chr8_+_27042555 1.70 ENSMUST00000033875.8
ENSMUST00000098851.4
proline synthetase co-transcribed
chr4_-_141846359 1.69 ENSMUST00000037059.10
chymotrypsin C (caldecrin)
chr5_+_90518932 1.67 ENSMUST00000113179.2
ENSMUST00000128740.1
afamin
chr6_+_137754529 1.65 ENSMUST00000087675.6
2-deoxyribose-5-phosphate aldolase homolog (C. elegans)
chr7_-_133782721 1.61 ENSMUST00000063669.1
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr7_-_127935429 1.60 ENSMUST00000141385.1
ENSMUST00000156152.1
protease, serine, 36
chr11_+_23665615 1.58 ENSMUST00000109525.1
ENSMUST00000020520.4
pseudouridylate synthase 10
chr8_-_72443772 1.51 ENSMUST00000019876.5
calreticulin 3
chr13_+_55152640 1.47 ENSMUST00000005452.5
fibroblast growth factor receptor 4
chr5_-_92215345 1.46 ENSMUST00000031356.4
cDNA sequence U90926
chr17_-_36032682 1.44 ENSMUST00000102678.4
histocompatibility 2, T region locus 23
chr7_-_41448641 1.42 ENSMUST00000165029.1
vomeronasal 2, receptor 57
chrX_-_97377190 1.41 ENSMUST00000037353.3
ectodysplasin A2 receptor
chr6_-_124636085 1.38 ENSMUST00000068797.2
predicted gene 5077
chr9_-_107679592 1.37 ENSMUST00000010205.7
guanine nucleotide binding protein, alpha transducing 1
chr13_+_93674403 1.33 ENSMUST00000048001.6
dimethylglycine dehydrogenase precursor
chr13_-_8871751 1.33 ENSMUST00000175958.1
WD repeat domain 37
chr7_+_119896292 1.32 ENSMUST00000106517.1
LYR motif containing 1
chr18_-_3299452 1.31 ENSMUST00000126578.1
cAMP responsive element modulator
chr9_-_57440084 1.30 ENSMUST00000085709.4
phosphopantothenoylcysteine decarboxylase
chr2_+_29761528 1.28 ENSMUST00000113810.2
ENSMUST00000113809.2
ENSMUST00000113808.2
predicted gene 13547
chr9_-_71168657 1.28 ENSMUST00000113570.1
aquaporin 9
chr15_+_3270767 1.27 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
selenoprotein P, plasma, 1
chr16_-_87432597 1.26 ENSMUST00000039449.7
listerin E3 ubiquitin protein ligase 1
chr11_-_5707658 1.25 ENSMUST00000154330.1
mitochondrial ribosomal protein S24
chr4_+_155582476 1.22 ENSMUST00000105612.1
NAD kinase
chr6_-_114921778 1.22 ENSMUST00000032459.7
vestigial like 4 (Drosophila)
chr1_+_165788681 1.22 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
CD247 antigen
chr8_+_88174560 1.22 ENSMUST00000074808.2
RIKEN cDNA 9430002A10 gene
chr17_-_45685973 1.22 ENSMUST00000145873.1
transmembrane protein 63b
chr4_-_19570073 1.19 ENSMUST00000029885.4
copine III
chr11_-_50202954 1.15 ENSMUST00000136936.1
sequestosome 1
chr4_+_129287614 1.13 ENSMUST00000102599.3
syncoilin
chr19_+_29945782 1.11 ENSMUST00000025724.8
interleukin 33
chr7_+_80246529 1.09 ENSMUST00000107381.1
tubulin tyrosine ligase-like family, member 13
chr13_+_55727345 1.08 ENSMUST00000124968.1
ENSMUST00000021958.5
pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr7_+_25619404 1.07 ENSMUST00000077338.5
ENSMUST00000085953.3
ATP5S-like
chr18_+_37435602 1.05 ENSMUST00000055495.5
protocadherin beta 12
chr9_-_64341145 1.05 ENSMUST00000120760.1
ENSMUST00000168844.2
DIS3 mitotic control homolog (S. cerevisiae)-like
chr5_+_3845171 1.04 ENSMUST00000044039.1
ENSMUST00000143027.1
leucine rich repeats and death domain containing 1
chr11_-_73326807 1.04 ENSMUST00000134079.1
aspartoacylase
chr1_+_165788746 1.03 ENSMUST00000161559.2
CD247 antigen
chr7_+_80246375 1.03 ENSMUST00000058266.6
tubulin tyrosine ligase-like family, member 13
chr13_-_67081503 1.01 ENSMUST00000109742.3
zinc finger protein 708
chr18_+_33464163 1.00 ENSMUST00000097634.3
predicted gene 10549
chr13_+_54071815 0.99 ENSMUST00000021930.8
sideroflexin 1
chr17_+_94873986 0.98 ENSMUST00000108007.4
predicted gene, 20939
chr17_+_46496753 0.97 ENSMUST00000046497.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr9_-_64341288 0.96 ENSMUST00000068367.7
DIS3 mitotic control homolog (S. cerevisiae)-like
chr5_-_24704656 0.94 ENSMUST00000181925.1
predicted gene, 26648
chr15_-_36164872 0.94 ENSMUST00000058643.3
F-box protein 43
chr6_-_131247342 0.94 ENSMUST00000032306.8
ENSMUST00000088867.6
killer cell lectin-like receptor, subfamily A, member 2
chr4_+_155451570 0.93 ENSMUST00000135407.1
ENSMUST00000105619.1
RIKEN cDNA C030017K20 gene
chr13_-_93674300 0.92 ENSMUST00000015941.7
betaine-homocysteine methyltransferase 2
chr8_+_94532990 0.91 ENSMUST00000048653.2
ENSMUST00000109537.1
copine II
chr11_-_106779483 0.90 ENSMUST00000021060.5
polymerase (DNA directed), gamma 2, accessory subunit
chr1_-_9962809 0.89 ENSMUST00000097824.2
predicted gene 10567
chr16_+_20097554 0.88 ENSMUST00000023509.3
kelch-like 24
chr11_-_77787747 0.87 ENSMUST00000092883.2
predicted gene 10277
chr5_-_104021919 0.87 ENSMUST00000031251.9
hydroxysteroid (17-beta) dehydrogenase 11
chrX_-_97377150 0.86 ENSMUST00000113832.1
ectodysplasin A2 receptor
chr5_-_86327736 0.85 ENSMUST00000122377.1
transmembrane protease, serine 11d
chr3_+_19985612 0.85 ENSMUST00000172860.1
ceruloplasmin
chr4_+_80910646 0.85 ENSMUST00000055922.3
leucine rich adaptor protein 1-like
chr11_-_115627948 0.84 ENSMUST00000154623.1
ENSMUST00000106503.3
ENSMUST00000141614.1
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr1_+_74391479 0.84 ENSMUST00000027367.7
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr6_-_99632376 0.84 ENSMUST00000176255.1
predicted gene 20696
chr1_+_157506777 0.83 ENSMUST00000027881.8
SEC16 homolog B (S. cerevisiae)
chr1_+_157506728 0.83 ENSMUST00000086130.2
SEC16 homolog B (S. cerevisiae)
chr6_-_98342728 0.82 ENSMUST00000164491.1
predicted gene 765
chr2_-_121380940 0.82 ENSMUST00000038389.8
stereocilin
chr1_-_133701881 0.81 ENSMUST00000167348.1
predicted gene, 17678
chr17_+_46110982 0.81 ENSMUST00000024763.3
ENSMUST00000123646.1
mitochondrial ribosomal protein S18A
chr10_-_127751707 0.80 ENSMUST00000079692.5
G protein-coupled receptor 182
chr11_-_83578496 0.79 ENSMUST00000019266.5
chemokine (C-C motif) ligand 9
chr10_-_20724696 0.79 ENSMUST00000170265.1
phosphodiesterase 7B
chr9_+_123806468 0.75 ENSMUST00000049810.7
chemokine (C-X-C motif) receptor 6
chr3_-_87748619 0.74 ENSMUST00000023846.4
leucine rich repeat containing 71
chr2_-_6130117 0.73 ENSMUST00000126551.1
ENSMUST00000054254.5
ENSMUST00000114942.2
proline and serine rich 2
chr14_-_55643800 0.71 ENSMUST00000122358.1
transmembrane 9 superfamily member 1
chr2_-_32431104 0.71 ENSMUST00000127961.1
ENSMUST00000136361.1
ENSMUST00000052119.7
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr14_-_55643523 0.71 ENSMUST00000132338.1
transmembrane 9 superfamily member 1
chr6_+_94500313 0.71 ENSMUST00000061118.8
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26
chr17_-_34305715 0.70 ENSMUST00000174074.1
predicted gene 20513
chr17_+_23853519 0.70 ENSMUST00000061725.7
protease, serine, 32
chr17_+_44188564 0.70 ENSMUST00000024755.5
chloride intracellular channel 5
chr11_+_4620067 0.69 ENSMUST00000109941.1
predicted gene 11032
chr3_+_138143846 0.68 ENSMUST00000159481.1
tRNA methyltransferase 10A
chr10_-_20725023 0.67 ENSMUST00000020165.7
phosphodiesterase 7B
chr3_+_138143888 0.67 ENSMUST00000161141.1
tRNA methyltransferase 10A
chr2_+_11705287 0.67 ENSMUST00000135341.1
ENSMUST00000138349.1
ENSMUST00000123600.2
interleukin 15 receptor, alpha chain
chr6_-_42472200 0.65 ENSMUST00000170504.1
olfactory receptor 457
chr3_-_101924378 0.65 ENSMUST00000106928.3
solute carrier family 22 (organic anion/cation transporter), member 15
chr6_-_42461017 0.65 ENSMUST00000090156.1
olfactory receptor 458
chr9_+_43829963 0.63 ENSMUST00000180221.1
predicted gene 3898
chr4_-_141139727 0.62 ENSMUST00000148204.1
ENSMUST00000102487.3
SUZ RNA binding domain containing 1
chr13_-_21402688 0.62 ENSMUST00000117721.1
ENSMUST00000070785.8
ENSMUST00000116433.1
ENSMUST00000116434.3
zinc finger with KRAB and SCAN domains 3
chr5_-_115134907 0.62 ENSMUST00000060798.5
unc-119 homolog B (C. elegans)
chr10_+_75589363 0.62 ENSMUST00000072217.2
gamma-glutamyltransferase 5
chr16_-_62786742 0.61 ENSMUST00000152553.1
ENSMUST00000063089.5
NOL1/NOP2/Sun domain family member 3
chr14_-_55643720 0.61 ENSMUST00000138085.1
transmembrane 9 superfamily member 1
chrX_+_170009892 0.59 ENSMUST00000180251.1
predicted gene, 21887
chr13_-_46191048 0.58 ENSMUST00000072437.3
predicted gene 10113
chr5_+_121803008 0.58 ENSMUST00000161159.1
ataxin 2
chr5_-_121527186 0.57 ENSMUST00000152270.1
MAP kinase-activated protein kinase 5
chr10_-_127522428 0.57 ENSMUST00000026470.4
serine hydroxymethyltransferase 2 (mitochondrial)
chr3_+_89202916 0.56 ENSMUST00000077367.4
ENSMUST00000167998.1
glucosidase, beta, acid
chr9_+_19641224 0.55 ENSMUST00000079042.6
zinc finger protein 317
chr2_-_151432392 0.55 ENSMUST00000127020.1
predicted gene 14152
chr9_-_37712277 0.54 ENSMUST00000104875.1
olfactory receptor 160
chr4_+_15957923 0.52 ENSMUST00000029879.8
ENSMUST00000149069.1
nibrin
chr4_+_88850087 0.52 ENSMUST00000094972.1
interferon alpha 1
chr13_-_32781716 0.52 ENSMUST00000134352.1
ENSMUST00000057428.4
myosin light chain kinase family, member 4
chr5_+_121802230 0.52 ENSMUST00000162995.1
ataxin 2
chr13_-_74376566 0.52 ENSMUST00000091481.2
zinc finger protein 72
chr17_-_53539411 0.51 ENSMUST00000056198.3
protein phosphatase 2C-like domain containing 1
chr4_-_116821501 0.51 ENSMUST00000055436.3
4-hydroxyphenylpyruvate dioxygenase-like
chr8_+_83566671 0.51 ENSMUST00000036996.5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
chr15_-_96699698 0.51 ENSMUST00000023099.6
solute carrier family 38, member 2
chr13_+_66904914 0.50 ENSMUST00000168767.2
predicted gene 10767
chr6_+_113333304 0.50 ENSMUST00000147945.1
8-oxoguanine DNA-glycosylase 1
chr7_-_121981669 0.50 ENSMUST00000057576.7
component of oligomeric golgi complex 7
chr5_-_130255525 0.50 ENSMUST00000026387.4
Shwachman-Bodian-Diamond syndrome homolog (human)
chr1_+_180109192 0.49 ENSMUST00000143176.1
ENSMUST00000135056.1
CDC42 binding protein kinase alpha
chr11_-_115048372 0.49 ENSMUST00000092459.3
CD300 antigen like family member H
chr14_+_44197661 0.49 ENSMUST00000166350.1
predicted gene 8212
chr17_+_29274078 0.49 ENSMUST00000149405.2
cDNA sequence BC004004
chr9_+_18409094 0.49 ENSMUST00000098973.2
upstream binding transcription factor, RNA polymerase I-like 1
chr2_-_126151968 0.47 ENSMUST00000110448.2
ENSMUST00000110446.2
family with sequence similarity 227, member B
chr5_-_143138200 0.47 ENSMUST00000164536.2
olfactory receptor 718, pseudogene 1
chr3_+_30746325 0.47 ENSMUST00000108262.3
sterile alpha motif domain containing 7
chr2_+_136713444 0.46 ENSMUST00000028727.4
ENSMUST00000110098.3
synaptosomal-associated protein 25
chr5_-_76905463 0.46 ENSMUST00000146570.1
ENSMUST00000142450.1
ENSMUST00000120963.1
aminoadipate-semialdehyde dehydrogenase
chr10_+_123264076 0.46 ENSMUST00000050756.7
family with sequence similarity 19, member A2
chr11_+_101627942 0.46 ENSMUST00000010506.3
RAD52 motif 1
chr11_-_100613334 0.45 ENSMUST00000146840.1
DnaJ (Hsp40) homolog, subfamily C, member 7
chr7_+_127470354 0.45 ENSMUST00000106292.1
proline rich 14
chrX_-_134111852 0.45 ENSMUST00000033610.6
NADPH oxidase 1
chr5_-_65335597 0.45 ENSMUST00000172660.1
ENSMUST00000172732.1
ENSMUST00000031092.8
replication factor C (activator 1) 1
chrX_-_7907835 0.44 ENSMUST00000085330.4
predicted gene 10491
chr16_+_17331371 0.43 ENSMUST00000023450.6
ENSMUST00000161034.1
serine (or cysteine) peptidase inhibitor, clade D, member 1
chr11_-_93965957 0.43 ENSMUST00000021220.3
NME/NM23 nucleoside diphosphate kinase 1
chr6_-_130233322 0.43 ENSMUST00000032286.6
killer cell lectin-like receptor, subfamily A, member 7
chr10_+_104195397 0.42 ENSMUST00000163113.2
predicted gene 4340
chr10_+_104178378 0.42 ENSMUST00000179258.1
predicted gene, 21312
chr10_+_104186887 0.42 ENSMUST00000177792.1
predicted gene, 20765
chr1_+_58802492 0.42 ENSMUST00000165549.1
caspase 8
chrX_-_126833977 0.41 ENSMUST00000180241.1
RIKEN cDNA 4932411N23 gene
chr10_-_100382539 0.41 ENSMUST00000164322.2
predicted gene 4312
chr2_+_126152141 0.41 ENSMUST00000170908.1
DTW domain containing 1
chr17_-_28915314 0.41 ENSMUST00000062357.4
RIKEN cDNA 4930539E08 gene
chr7_-_11166148 0.41 ENSMUST00000067210.4
ENSMUST00000094850.4
ENSMUST00000165848.2
zinc finger and SCAN domain containing 4D
chr7_-_47310241 0.40 ENSMUST00000179005.1
MAS-related GPR, member X3, pseudogene
chr14_-_26442824 0.40 ENSMUST00000136635.1
ENSMUST00000125437.1
sarcolemma associated protein
chr6_+_6863269 0.40 ENSMUST00000160937.2
ENSMUST00000171311.1
distal-less homeobox 6
chr1_+_60181495 0.39 ENSMUST00000160834.1
neurobeachin like 1
chr9_+_56937462 0.39 ENSMUST00000034827.8
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chrX_-_7041619 0.39 ENSMUST00000115752.1
cyclin B3
chr3_+_41742615 0.39 ENSMUST00000146165.1
ENSMUST00000119572.1
ENSMUST00000108065.2
ENSMUST00000120167.1
ENSMUST00000026867.7
ENSMUST00000026868.7
DNA segment, Chr 3, ERATO Doi 751, expressed
chr18_+_56562443 0.37 ENSMUST00000130163.1
ENSMUST00000132628.1
phosphorylated adaptor for RNA export
chr2_-_37647199 0.37 ENSMUST00000028279.3
spermatid perinuclear RNA binding protein
chr9_+_50617516 0.37 ENSMUST00000141366.1
PIH1 domain containing 2
chr5_-_145010643 0.37 ENSMUST00000110673.1
karyopherin alpha 7 (importin alpha 8)
chr6_-_39377681 0.36 ENSMUST00000090243.4
solute carrier family 37 (glycerol-3-phosphate transporter), member 3
chr17_+_49428359 0.36 ENSMUST00000165390.2
ENSMUST00000024797.9
ENSMUST00000173033.1
molybdenum cofactor synthesis 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb16

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 19.3 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
1.8 7.1 GO:0032379 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
1.0 3.0 GO:0003167 atrioventricular bundle cell differentiation(GO:0003167)
1.0 5.0 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.8 4.8 GO:0018992 germ-line sex determination(GO:0018992)
0.7 2.0 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343)
0.6 3.5 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.6 1.7 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.6 5.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.5 1.5 GO:0061144 alveolar secondary septum development(GO:0061144)
0.4 1.6 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.4 4.1 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.4 1.4 GO:0002488 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.3 1.3 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.3 0.9 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.3 1.4 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342)
0.2 4.9 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.2 1.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.2 0.9 GO:0006710 androgen catabolic process(GO:0006710)
0.2 0.8 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.2 2.9 GO:0015747 urate transport(GO:0015747)
0.2 1.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 0.6 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.2 1.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.2 2.0 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.2 1.0 GO:0006083 acetate metabolic process(GO:0006083)
0.2 1.3 GO:0019695 choline metabolic process(GO:0019695)
0.2 1.7 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.2 0.6 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 1.6 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.2 0.3 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.2 0.9 GO:0071265 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.1 0.7 GO:0051182 coenzyme transport(GO:0051182)
0.1 0.6 GO:1903061 positive regulation of protein lipidation(GO:1903061) positive regulation of neuronal action potential(GO:1904457)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.9 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 0.4 GO:0051030 snRNA transport(GO:0051030)
0.1 1.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.1 0.6 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.2 GO:0046066 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.1 1.0 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.3 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.1 0.5 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 1.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.3 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.1 2.2 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.5 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.9 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.1 0.6 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 1.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.5 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.1 1.5 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.1 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.3 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.5 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 1.8 GO:0007035 vacuolar acidification(GO:0007035)
0.1 0.3 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 1.0 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.5 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.4 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.1 1.3 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.5 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 3.3 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 0.6 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 1.8 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 2.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:1904305 negative regulation of gastro-intestinal system smooth muscle contraction(GO:1904305) regulation of small intestine smooth muscle contraction(GO:1904347) negative regulation of small intestine smooth muscle contraction(GO:1904348) small intestine smooth muscle contraction(GO:1990770)
0.0 0.6 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 1.3 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0060618 nipple development(GO:0060618)
0.0 0.5 GO:0032328 alanine transport(GO:0032328)
0.0 2.1 GO:0070207 protein homotrimerization(GO:0070207)
0.0 1.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.4 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.3 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 2.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.4 GO:0046037 GMP metabolic process(GO:0046037)
0.0 1.7 GO:0051180 vitamin transport(GO:0051180)
0.0 0.8 GO:0046688 response to copper ion(GO:0046688)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.7 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.7 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.6 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.7 GO:0014823 response to activity(GO:0014823)
0.0 0.8 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.4 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.5 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.0 1.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.5 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 2.3 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.8 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.8 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.0 0.9 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 1.9 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.0 0.5 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 2.2 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.4 4.9 GO:0005579 membrane attack complex(GO:0005579)
0.4 1.2 GO:0044753 amphisome(GO:0044753)
0.3 5.0 GO:0045180 basal cortex(GO:0045180)
0.3 2.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 2.0 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.6 GO:0070552 BRISC complex(GO:0070552)
0.1 0.4 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.1 1.8 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 1.3 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.4 GO:0034457 Mpp10 complex(GO:0034457)
0.1 1.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 0.6 GO:0043202 lysosomal lumen(GO:0043202)
0.1 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.1 4.8 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.8 GO:0060091 kinocilium(GO:0060091)
0.1 2.1 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 7.6 GO:0072562 blood microparticle(GO:0072562)
0.0 2.9 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.6 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 1.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.0 0.9 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.8 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.9 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 1.4 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.1 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.7 19.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.6 1.7 GO:0008431 vitamin E binding(GO:0008431)
0.5 5.0 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.3 1.0 GO:0019807 aspartoacylase activity(GO:0019807)
0.3 1.3 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.3 2.0 GO:0004556 alpha-amylase activity(GO:0004556)
0.3 1.3 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.2 1.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.2 2.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 2.9 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 0.6 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2 0.6 GO:0004348 glucosylceramidase activity(GO:0004348)
0.2 2.0 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.2 0.5 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.2 1.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.9 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 1.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.4 GO:0030519 snoRNP binding(GO:0030519)
0.1 1.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 0.8 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.1 0.8 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.1 0.7 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 1.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.4 GO:0035877 death effector domain binding(GO:0035877)
0.1 4.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 1.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.8 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 1.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.8 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 0.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.7 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 1.7 GO:0016594 glycine binding(GO:0016594)
0.1 0.7 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 1.4 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.1 0.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.3 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 1.2 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 1.9 GO:0070330 aromatase activity(GO:0070330)
0.1 0.9 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 0.3 GO:0043532 angiostatin binding(GO:0043532)
0.1 1.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 0.3 GO:0004043 L-aminoadipate-semialdehyde dehydrogenase activity(GO:0004043)
0.1 0.6 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 1.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.0 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 1.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 1.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 3.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 3.4 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 6.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.3 GO:0050733 RS domain binding(GO:0050733)
0.0 1.1 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.7 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.6 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 2.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.6 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.0 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 2.5 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.0 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 1.8 GO:0016853 isomerase activity(GO:0016853)
0.0 0.1 GO:0008301 DNA binding, bending(GO:0008301)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 19.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 0.4 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 5.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 2.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 3.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 3.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.2 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.6 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 1.6 PID FGF PATHWAY FGF signaling pathway
0.0 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.2 2.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 3.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 4.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 5.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.5 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 1.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 2.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.0 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.4 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.3 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.8 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.5 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import