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GSE58827: Dynamics of the Mouse Liver

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Results for Zfp110

Z-value: 2.60

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Transcription factors associated with Zfp110

Gene Symbol Gene ID Gene Info
Zfp110
ENSMUSG00000058638.7 zinc finger protein 110

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp110mm10_v2_chr7_+_12834743_128348110.096.1e-01Click!

Activity profile of Zfp110 motif

Sorted Z-values of Zfp110 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_21691860 35.91 ENSMUST00000072133.4
Gm10226
predicted gene 10226
chr17_+_21690766 32.91 ENSMUST00000097384.1
Gm10509
predicted gene 10509
chr9_-_124493793 32.54 ENSMUST00000178787.1
Gm21836
predicted gene, 21836
chr19_-_61297069 28.25 ENSMUST00000179346.1
Gm21060
predicted gene, 21060
chr2_+_177508570 21.58 ENSMUST00000108940.2
Gm14403
predicted gene 14403
chr17_+_16972910 19.03 ENSMUST00000071374.5
BC002059
cDNA sequence BC002059
chr13_-_66852017 18.04 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr13_-_66851513 17.48 ENSMUST00000169322.1
Gm17404
predicted gene, 17404
chr8_-_69373383 15.40 ENSMUST00000072427.4
Gm10033
predicted gene 10033
chr2_-_175131864 13.84 ENSMUST00000108929.2
Gm14399
predicted gene 14399
chr5_-_110046486 13.68 ENSMUST00000167969.1
Gm17655
predicted gene, 17655
chr2_+_176236860 11.23 ENSMUST00000166464.1
2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr2_-_176917518 9.91 ENSMUST00000108931.2
Gm14296
predicted gene 14296
chr12_-_20900867 9.40 ENSMUST00000079237.5
Zfp125
zinc finger protein 125
chr13_-_66227573 9.05 ENSMUST00000167981.2
Gm10772
predicted gene 10772
chr7_-_42578588 8.92 ENSMUST00000179470.1
Gm21028
predicted gene, 21028
chr12_-_23780265 7.70 ENSMUST00000072014.4
Gm10330
predicted gene 10330
chr13_+_65512678 6.28 ENSMUST00000081471.2
Gm10139
predicted gene 10139
chr17_-_22007301 4.13 ENSMUST00000075018.3
Gm9772
predicted gene 9772
chr8_-_69373914 2.81 ENSMUST00000095282.1
Gm10311
predicted gene 10311
chr2_-_150255591 2.04 ENSMUST00000063463.5
Gm21994
predicted gene 21994
chr17_+_25370575 1.47 ENSMUST00000024999.8
Tpsg1
tryptase gamma 1
chr17_+_25370550 1.36 ENSMUST00000162021.1
Tpsg1
tryptase gamma 1
chrX_-_93632113 1.30 ENSMUST00000006856.2
Pola1
polymerase (DNA directed), alpha 1
chr2_-_59160644 1.28 ENSMUST00000077687.5
Ccdc148
coiled-coil domain containing 148
chr12_-_103675464 1.23 ENSMUST00000095451.1
Gm46
predicted gene 46
chr10_+_69925484 1.19 ENSMUST00000182692.1
ENSMUST00000092433.5
Ank3
ankyrin 3, epithelial
chr9_+_4309719 1.16 ENSMUST00000049648.7
Kbtbd3
kelch repeat and BTB (POZ) domain containing 3
chr2_-_32775330 1.12 ENSMUST00000161089.1
ENSMUST00000066478.2
ENSMUST00000161950.1
Ttc16
tetratricopeptide repeat domain 16
chr15_-_103215285 0.83 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
Cbx5
chromobox 5
chr4_-_94979063 0.80 ENSMUST00000075872.3
Mysm1
myb-like, SWIRM and MPN domains 1
chr6_+_17306415 0.80 ENSMUST00000150901.1
Cav1
caveolin 1, caveolae protein
chrY_+_897782 0.78 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr4_-_43669141 0.75 ENSMUST00000056474.6
Fam221b
family with sequence similarity 221, member B
chr7_-_24333959 0.59 ENSMUST00000069562.4
Tescl
tescalcin-like
chr2_-_150485091 0.59 ENSMUST00000109914.1
Zfp345
zinc finger protein 345
chr12_-_16800674 0.56 ENSMUST00000162112.1
Greb1
gene regulated by estrogen in breast cancer protein
chr14_-_55116935 0.53 ENSMUST00000022819.5
Jph4
junctophilin 4
chr7_-_104288094 0.37 ENSMUST00000098179.2
Trim5
tripartite motif-containing 5
chr7_+_92062392 0.33 ENSMUST00000098308.2
Dlg2
discs, large homolog 2 (Drosophila)
chr6_+_22288221 0.32 ENSMUST00000128245.1
ENSMUST00000031681.3
ENSMUST00000148639.1
Wnt16
wingless-related MMTV integration site 16
chr4_+_90223625 0.30 ENSMUST00000080541.4
Zfp352
zinc finger protein 352
chr7_-_122021143 0.21 ENSMUST00000033160.8
Gga2
golgi associated, gamma adaptin ear containing, ARF binding protein 2
chr2_-_119541513 0.18 ENSMUST00000171024.1
Exd1
exonuclease 3'-5' domain containing 1
chr2_+_59160838 0.17 ENSMUST00000102754.4
ENSMUST00000168631.1
ENSMUST00000123908.1
Pkp4
plakophilin 4
chr4_+_134864536 0.16 ENSMUST00000030627.7
Rhd
Rh blood group, D antigen
chr6_-_53978662 0.16 ENSMUST00000166545.1
Cpvl
carboxypeptidase, vitellogenic-like
chr4_+_43669266 0.13 ENSMUST00000107864.1
Tmem8b
transmembrane protein 8B
chr5_-_66173051 0.11 ENSMUST00000113726.1
Rbm47
RNA binding motif protein 47
chr9_-_4309432 0.10 ENSMUST00000051589.7
Aasdhppt
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp110

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269) leading strand elongation(GO:0006272)
0.2 0.8 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.7 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1 0.8 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 1.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0006553 lysine metabolic process(GO:0006553)
0.0 0.3 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 50.9 GO:0006355 regulation of transcription, DNA-templated(GO:0006355)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.4 GO:1990462 omegasome(GO:1990462)
0.1 1.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.8 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.8 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 1.3 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 53.7 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.4 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 1.2 GO:0030507 spectrin binding(GO:0030507)
0.0 2.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 2.1 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins