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GSE58827: Dynamics of the Mouse Liver

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Results for Zfp282

Z-value: 0.91

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Transcription factors associated with Zfp282

Gene Symbol Gene ID Gene Info
Zfp282
ENSMUSG00000025821.9 zinc finger protein 282

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp282mm10_v2_chr6_+_47877204_478772040.782.6e-08Click!

Activity profile of Zfp282 motif

Sorted Z-values of Zfp282 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_90669063 11.77 ENSMUST00000069927.8
S100a8
S100 calcium binding protein A8 (calgranulin A)
chr11_-_69617879 11.72 ENSMUST00000005334.2
Shbg
sex hormone binding globulin
chr14_+_80000292 10.89 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr7_-_103843154 10.34 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr14_-_70627008 9.89 ENSMUST00000110984.2
Dmtn
dematin actin binding protein
chr7_+_143005046 8.77 ENSMUST00000009396.6
Tspan32
tetraspanin 32
chr10_-_19851459 7.76 ENSMUST00000059805.4
Slc35d3
solute carrier family 35, member D3
chr15_+_75156693 7.14 ENSMUST00000023246.3
Ly6g
lymphocyte antigen 6 complex, locus G
chr6_-_83527986 4.12 ENSMUST00000121731.1
Actg2
actin, gamma 2, smooth muscle, enteric
chrX_+_135993820 3.96 ENSMUST00000058119.7
Arxes2
adipocyte-related X-chromosome expressed sequence 2
chr13_-_95525239 3.77 ENSMUST00000022185.8
F2rl1
coagulation factor II (thrombin) receptor-like 1
chr6_-_83527773 3.69 ENSMUST00000152029.1
Actg2
actin, gamma 2, smooth muscle, enteric
chr6_-_83527452 3.57 ENSMUST00000141904.1
Actg2
actin, gamma 2, smooth muscle, enteric
chr9_-_114781986 3.46 ENSMUST00000035009.8
ENSMUST00000084867.7
Cmtm7
CKLF-like MARVEL transmembrane domain containing 7
chr7_-_25005895 2.99 ENSMUST00000102858.3
ENSMUST00000080882.6
Atp1a3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr2_-_25095125 2.96 ENSMUST00000114373.1
Noxa1
NADPH oxidase activator 1
chrX_+_106920618 2.93 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr4_-_53262547 2.47 ENSMUST00000098075.2
AI427809
expressed sequence AI427809
chr2_-_160912292 2.41 ENSMUST00000109454.1
ENSMUST00000057169.4
Emilin3
elastin microfibril interfacer 3
chr2_-_25095149 2.40 ENSMUST00000044018.7
Noxa1
NADPH oxidase activator 1
chr16_+_11066292 2.38 ENSMUST00000089011.4
Snn
stannin
chr1_+_134455524 2.37 ENSMUST00000112232.1
ENSMUST00000027725.4
ENSMUST00000116528.1
Klhl12
kelch-like 12
chr1_+_74409376 2.31 ENSMUST00000027366.6
Vil1
villin 1
chr12_+_9574437 2.10 ENSMUST00000057021.7
Osr1
odd-skipped related 1 (Drosophila)
chr11_+_35121126 2.09 ENSMUST00000069837.3
Slit3
slit homolog 3 (Drosophila)
chr17_-_50094277 2.03 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr10_-_93589621 2.03 ENSMUST00000020203.6
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr9_+_120571498 1.87 ENSMUST00000165532.1
Rpl14
ribosomal protein L14
chr10_-_51631458 1.80 ENSMUST00000020062.3
Gprc6a
G protein-coupled receptor, family C, group 6, member A
chr2_-_125625065 1.78 ENSMUST00000089776.2
Cep152
centrosomal protein 152
chr19_-_6858179 1.74 ENSMUST00000113440.1
Ccdc88b
coiled-coil domain containing 88B
chr9_-_95845215 1.69 ENSMUST00000093800.2
Pls1
plastin 1 (I-isoform)
chr7_-_28547109 1.65 ENSMUST00000057974.3
Nccrp1
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr11_-_94782500 1.52 ENSMUST00000162809.2
Tmem92
transmembrane protein 92
chr12_-_87443800 1.42 ENSMUST00000162961.1
Alkbh1
alkB, alkylation repair homolog 1 (E. coli)
chr5_-_65391380 1.41 ENSMUST00000120094.1
ENSMUST00000118543.1
ENSMUST00000127874.1
Rpl9
ribosomal protein L9
chr7_-_30072801 1.38 ENSMUST00000183115.1
ENSMUST00000182919.1
ENSMUST00000183190.1
ENSMUST00000080834.8
Zfp82
zinc finger protein 82
chr17_+_26941420 1.36 ENSMUST00000081285.3
ENSMUST00000177932.1
Syngap1
synaptic Ras GTPase activating protein 1 homolog (rat)
chr5_-_65391408 1.34 ENSMUST00000057885.6
Rpl9
ribosomal protein L9
chr8_-_23237623 1.32 ENSMUST00000033950.5
Gins4
GINS complex subunit 4 (Sld5 homolog)
chr17_-_33685386 1.31 ENSMUST00000139302.1
ENSMUST00000087582.5
ENSMUST00000114385.2
Hnrnpm
heterogeneous nuclear ribonucleoprotein M
chr19_-_5085483 1.24 ENSMUST00000140389.1
ENSMUST00000151413.1
ENSMUST00000077066.7
Tmem151a
transmembrane protein 151A
chr11_-_68973840 1.20 ENSMUST00000038644.4
Rangrf
RAN guanine nucleotide release factor
chr10_+_93453382 1.07 ENSMUST00000016033.7
Lta4h
leukotriene A4 hydrolase
chr4_-_126202583 1.04 ENSMUST00000106142.1
ENSMUST00000169403.1
ENSMUST00000130334.1
Thrap3
thyroid hormone receptor associated protein 3
chr16_+_97489994 1.01 ENSMUST00000177820.1
Gm9242
predicted pseudogene 9242
chr17_+_35866606 1.01 ENSMUST00000113814.4
Ppp1r18
protein phosphatase 1, regulatory subunit 18
chrX_+_166344692 0.90 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b
glycoprotein m6b
chr11_-_94782703 0.89 ENSMUST00000100554.1
Tmem92
transmembrane protein 92
chr17_-_46680870 0.79 ENSMUST00000165007.1
ENSMUST00000071841.5
Klhdc3
kelch domain containing 3
chr9_+_18427543 0.75 ENSMUST00000053326.9
Gm5612
predicted gene 5612
chr10_+_127195240 0.62 ENSMUST00000181578.1
F420014N23Rik
RIKEN cDNA F420014N23 gene
chr4_+_14864076 0.58 ENSMUST00000029875.3
Tmem55a
transmembrane protein 55A
chr4_-_126202757 0.57 ENSMUST00000080919.5
Thrap3
thyroid hormone receptor associated protein 3
chr2_+_25289899 0.57 ENSMUST00000028337.6
Lrrc26
leucine rich repeat containing 26
chr7_+_16738410 0.51 ENSMUST00000086112.6
Ap2s1
adaptor-related protein complex 2, sigma 1 subunit
chr11_-_69549108 0.45 ENSMUST00000108659.1
Dnah2
dynein, axonemal, heavy chain 2
chrX_+_20617503 0.43 ENSMUST00000115375.1
ENSMUST00000115374.1
ENSMUST00000084383.3
Rbm10
RNA binding motif protein 10
chr18_-_35722330 0.42 ENSMUST00000133064.1
Ecscr
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr12_+_87443896 0.37 ENSMUST00000161023.1
ENSMUST00000160488.1
ENSMUST00000077462.7
ENSMUST00000160880.1
Slirp
SRA stem-loop interacting RNA binding protein
chr3_-_88951146 0.33 ENSMUST00000173135.1
Dap3
death associated protein 3
chr3_-_88951090 0.27 ENSMUST00000173021.1
Dap3
death associated protein 3
chr2_+_111378967 0.26 ENSMUST00000062407.2
Olfr1284
olfactory receptor 1284
chr1_+_86022105 0.26 ENSMUST00000131151.2
Spata3
spermatogenesis associated 3
chr7_-_105640308 0.23 ENSMUST00000133519.1
ENSMUST00000084782.2
ENSMUST00000131446.1
Arfip2
ADP-ribosylation factor interacting protein 2
chr4_+_102986343 0.19 ENSMUST00000030248.5
ENSMUST00000125417.1
Tctex1d1
Tctex1 domain containing 1
chr3_-_108398951 0.18 ENSMUST00000147251.1
Celsr2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr7_-_90265402 0.18 ENSMUST00000107221.1
ENSMUST00000107220.1
ENSMUST00000040413.1
Ccdc83
coiled-coil domain containing 83
chr3_+_122245625 0.16 ENSMUST00000178826.1
Gclm
glutamate-cysteine ligase, modifier subunit
chr3_+_122245557 0.15 ENSMUST00000029769.7
Gclm
glutamate-cysteine ligase, modifier subunit
chr12_+_69241832 0.15 ENSMUST00000063445.6
Klhdc1
kelch domain containing 1
chr6_-_135254170 0.15 ENSMUST00000111909.1
Gsg1
germ cell-specific gene 1
chr7_-_143740316 0.14 ENSMUST00000119499.1
Osbpl5
oxysterol binding protein-like 5
chr9_+_62677826 0.11 ENSMUST00000034774.8
Itga11
integrin alpha 11
chr11_+_23666479 0.10 ENSMUST00000143117.1
Pus10
pseudouridylate synthase 10
chrX_+_153558591 0.02 ENSMUST00000112573.1
ENSMUST00000056754.3
Cypt3
cysteine-rich perinuclear theca 3
chr12_+_72536342 0.01 ENSMUST00000044352.6
Pcnxl4
pecanex-like 4 (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp282

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.8 GO:0070488 neutrophil aggregation(GO:0070488)
3.3 9.9 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
2.6 7.8 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
1.3 10.3 GO:0015671 oxygen transport(GO:0015671)
1.3 3.8 GO:0070948 positive regulation of eosinophil degranulation(GO:0043311) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949) positive regulation of renin secretion into blood stream(GO:1900135) positive regulation of eosinophil activation(GO:1902568)
1.0 4.0 GO:1902896 terminal web assembly(GO:1902896)
0.9 8.8 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.9 3.5 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.7 2.1 GO:0072194 intermediate mesoderm development(GO:0048389) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098) kidney smooth muscle tissue development(GO:0072194)
0.4 1.4 GO:0035552 tRNA wobble cytosine modification(GO:0002101) oxidative single-stranded DNA demethylation(GO:0035552)
0.3 2.1 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.3 2.0 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.3 3.0 GO:0036376 sodium ion export from cell(GO:0036376)
0.3 5.4 GO:0060263 regulation of respiratory burst(GO:0060263)
0.3 1.8 GO:0098535 de novo centriole assembly(GO:0098535)
0.2 2.4 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.2 10.9 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.2 1.0 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.2 1.2 GO:0086043 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 0.9 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.1 1.4 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.1 0.4 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 2.9 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 1.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 2.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 1.7 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.4 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 1.1 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 2.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.2 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 11.7 GO:0048588 developmental cell growth(GO:0048588)
0.0 0.6 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.3 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 1.9 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.4 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 1.3 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 1.8 GO:0043200 response to amino acid(GO:0043200)
0.0 0.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.1 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 9.9 GO:0031095 platelet dense tubular network membrane(GO:0031095)
2.2 8.8 GO:0070442 integrin alphaIIb-beta3 complex(GO:0070442)
1.3 10.3 GO:0005833 hemoglobin complex(GO:0005833)
0.7 10.9 GO:0042581 specific granule(GO:0042581)
0.5 5.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.4 1.3 GO:0000811 GINS complex(GO:0000811)
0.4 2.0 GO:0005683 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.3 3.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 1.8 GO:0098536 deuterosome(GO:0098536)
0.2 1.7 GO:1990357 terminal web(GO:1990357)
0.2 3.8 GO:0031143 pseudopodium(GO:0031143)
0.2 1.3 GO:0042382 paraspeckles(GO:0042382)
0.2 2.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.3 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 1.8 GO:0032433 filopodium tip(GO:0032433)
0.1 11.4 GO:0072562 blood microparticle(GO:0072562)
0.1 11.8 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 1.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 4.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.4 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 7.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.2 GO:0014704 intercalated disc(GO:0014704)
0.0 2.4 GO:0005741 mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.3 GO:0031721 hemoglobin alpha binding(GO:0031721)
1.5 11.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.9 3.8 GO:0015057 thrombin receptor activity(GO:0015057)
0.9 7.8 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.7 5.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.6 5.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3 1.4 GO:0043734 DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.3 3.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.3 2.1 GO:0048495 Roundabout binding(GO:0048495)
0.2 1.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 9.9 GO:0030507 spectrin binding(GO:0030507)
0.1 0.3 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 1.3 GO:1990405 protein antigen binding(GO:1990405)
0.1 0.6 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 1.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 10.2 GO:0005496 steroid binding(GO:0005496)
0.0 2.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 2.7 GO:0019843 rRNA binding(GO:0019843)
0.0 12.6 GO:0045296 cadherin binding(GO:0045296)
0.0 1.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 3.3 GO:0005125 cytokine activity(GO:0005125)
0.0 1.3 GO:0003725 double-stranded RNA binding(GO:0003725)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 11.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 11.7 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.2 11.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 2.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 3.8 ST GA12 PATHWAY G alpha 12 Pathway
0.1 2.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 5.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.1 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 11.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 2.9 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 2.0 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 3.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 4.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 2.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 3.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism