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GSE58827: Dynamics of the Mouse Liver

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Results for Zfp784

Z-value: 0.72

Motif logo

Transcription factors associated with Zfp784

Gene Symbol Gene ID Gene Info
ENSMUSG00000043290.6 zinc finger protein 784

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp784mm10_v2_chr7_-_5038427_50384500.642.6e-05Click!

Activity profile of Zfp784 motif

Sorted Z-values of Zfp784 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_86078070 3.92 ENSMUST00000032069.5
adducin 2 (beta)
chr7_-_109170308 3.42 ENSMUST00000036992.7
LIM domain only 1
chr14_-_47418407 3.42 ENSMUST00000043296.3
discs, large (Drosophila) homolog-associated protein 5
chr14_-_70627008 3.05 ENSMUST00000110984.2
dematin actin binding protein
chr11_-_102088471 2.78 ENSMUST00000017458.4
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr13_-_100775844 2.70 ENSMUST00000075550.3
centromere protein H
chr6_+_86628174 2.60 ENSMUST00000043400.6
aspartic peptidase, retroviral-like 1
chr5_-_107726017 2.59 ENSMUST00000159263.2
growth factor independent 1
chr2_+_101624734 2.50 ENSMUST00000111227.1
recombination activating gene 2
chrX_-_139871637 2.49 ENSMUST00000033811.7
ENSMUST00000087401.5
microrchidia 4
chr1_-_133753681 2.30 ENSMUST00000125659.1
ENSMUST00000165602.2
ENSMUST00000048953.7
ATPase, Ca++ transporting, plasma membrane 4
chr2_+_118814195 2.29 ENSMUST00000110842.1
kinetochore-localized astrin/SPAG5 binding
chr5_+_122206792 2.17 ENSMUST00000145854.1
hydrogen voltage-gated channel 1
chr2_+_118814237 2.14 ENSMUST00000028803.7
ENSMUST00000126045.1
kinetochore-localized astrin/SPAG5 binding
chr5_+_123749696 2.12 ENSMUST00000031366.7
kinetochore associated 1
chr6_-_87981482 2.02 ENSMUST00000056403.5
H1 histone family, member X
chr3_+_88629442 2.01 ENSMUST00000176316.1
ENSMUST00000176879.1
rho/rac guanine nucleotide exchange factor (GEF) 2
chr16_-_4003750 1.99 ENSMUST00000171658.1
ENSMUST00000171762.1
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
chr2_+_118813995 1.97 ENSMUST00000134661.1
kinetochore-localized astrin/SPAG5 binding
chr4_-_88033328 1.96 ENSMUST00000078090.5
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr12_+_102129019 1.95 ENSMUST00000079020.4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr7_-_103813913 1.92 ENSMUST00000098192.3
hemoglobin, beta adult t chain
chr13_-_19824234 1.90 ENSMUST00000065335.2
G protein-coupled receptor 141
chr2_+_130277157 1.90 ENSMUST00000028890.8
ENSMUST00000159373.1
NOP56 ribonucleoprotein
chr9_+_57825918 1.85 ENSMUST00000165858.1
predicted gene 17231
chr7_+_142471838 1.85 ENSMUST00000038946.2
lymphocyte specific 1
chr7_+_142472080 1.82 ENSMUST00000105966.1
lymphocyte specific 1
chr6_-_124733067 1.81 ENSMUST00000173647.1
protein tyrosine phosphatase, non-receptor type 6
chr3_+_8509477 1.80 ENSMUST00000029002.7
stathmin-like 2
chr3_-_127499095 1.78 ENSMUST00000182594.1
ankyrin 2, brain
chr4_-_63172118 1.77 ENSMUST00000030042.2
kinesin family member 12
chr10_-_84533884 1.76 ENSMUST00000053871.3
cytoskeleton-associated protein 4
chr1_+_151571481 1.75 ENSMUST00000111875.1
family with sequence similarity 129, member A
chr3_+_88629499 1.63 ENSMUST00000175745.1
rho/rac guanine nucleotide exchange factor (GEF) 2
chr15_-_78572754 1.61 ENSMUST00000043214.6
RAS-related C3 botulinum substrate 2
chr18_-_68429235 1.61 ENSMUST00000052347.6
melanocortin 2 receptor
chr1_+_171767123 1.59 ENSMUST00000015460.4
signaling lymphocytic activation molecule family member 1
chr11_+_69964758 1.58 ENSMUST00000108597.1
ENSMUST00000060651.5
ENSMUST00000108596.1
claudin 7
chr7_-_103827922 1.56 ENSMUST00000023934.6
ENSMUST00000153218.1
hemoglobin, beta adult s chain
chr7_-_110862944 1.51 ENSMUST00000033050.3
lymphatic vessel endothelial hyaluronan receptor 1
chr7_-_25005895 1.44 ENSMUST00000102858.3
ENSMUST00000080882.6
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr13_+_21717626 1.43 ENSMUST00000091754.2
histone cluster 1, H3h
chr1_+_40324570 1.42 ENSMUST00000095020.3
interleukin 1 receptor-like 2
chr6_-_30958990 1.37 ENSMUST00000101589.3
Kruppel-like factor 14
chr16_-_92826004 1.37 ENSMUST00000023673.7
runt related transcription factor 1
chr4_-_4138432 1.36 ENSMUST00000070375.7
preproenkephalin
chr9_-_20952838 1.33 ENSMUST00000004202.9
DNA methyltransferase (cytosine-5) 1
chr2_+_125068118 1.33 ENSMUST00000070353.3
solute carrier family 24, member 5
chr16_-_74411292 1.33 ENSMUST00000117200.1
roundabout homolog 2 (Drosophila)
chr3_+_146404978 1.31 ENSMUST00000129978.1
synovial sarcoma, X breakpoint 2 interacting protein
chr9_-_120068263 1.31 ENSMUST00000064165.3
ENSMUST00000177637.1
chemokine (C-X3-C) receptor 1
chr12_-_40248073 1.29 ENSMUST00000169926.1
interferon-related developmental regulator 1
chrX_-_133898292 1.29 ENSMUST00000176718.1
ENSMUST00000176641.1
tetraspanin 6
chr10_-_30803075 1.24 ENSMUST00000068567.4
nuclear receptor coactivator 7
chr8_-_105637403 1.20 ENSMUST00000182046.1
predicted gene 5914
chr13_+_52596847 1.18 ENSMUST00000055087.6
spleen tyrosine kinase
chr5_+_37028329 1.18 ENSMUST00000173836.1
janus kinase and microtubule interacting protein 1
chr6_+_65778988 1.18 ENSMUST00000031976.7
ENSMUST00000081219.7
ENSMUST00000031973.6
ENSMUST00000172638.1
PR domain containing 5
chr12_+_85599388 1.17 ENSMUST00000050687.6
Jun dimerization protein 2
chr13_-_51567084 1.16 ENSMUST00000021898.5
src homology 2 domain-containing transforming protein C3
chr4_-_92191749 1.14 ENSMUST00000123179.1
predicted gene 12666
chr2_-_45113255 1.11 ENSMUST00000068415.4
ENSMUST00000127520.1
zinc finger E-box binding homeobox 2
chr5_-_24329556 1.10 ENSMUST00000115098.2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr6_-_28831747 1.09 ENSMUST00000062304.5
leucine rich repeat containing 4
chr1_+_151571373 1.09 ENSMUST00000148810.1
family with sequence similarity 129, member A
chr14_-_65425453 1.09 ENSMUST00000059339.5
prepronociceptin
chr6_-_67535783 1.08 ENSMUST00000058178.4
tumor-associated calcium signal transducer 2
chr13_+_48662989 1.06 ENSMUST00000021813.4
BarH-like homeobox 1
chr15_-_79834261 1.03 ENSMUST00000148358.1
chromobox 6
chr17_+_12119274 1.03 ENSMUST00000024594.2
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chrX_+_74329058 1.02 ENSMUST00000004326.3
plexin A3
chr3_+_146404631 1.02 ENSMUST00000106153.2
ENSMUST00000039021.4
ENSMUST00000106151.1
ENSMUST00000149262.1
synovial sarcoma, X breakpoint 2 interacting protein
chr16_-_17144415 0.99 ENSMUST00000115709.1
coiled-coil domain containing 116
chr19_+_4154606 0.98 ENSMUST00000061086.8
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr4_-_138757578 0.95 ENSMUST00000030526.6
phospholipase A2, group IIF
chr11_-_34783850 0.94 ENSMUST00000093193.5
ENSMUST00000101365.2
dedicator of cyto-kinesis 2
chr11_+_115974709 0.94 ENSMUST00000021107.7
ENSMUST00000106461.1
ENSMUST00000169928.1
integrin beta 4
chr10_+_53474964 0.91 ENSMUST00000168554.1
predicted gene 5423
chr14_+_70077375 0.91 ENSMUST00000035908.1
early growth response 3
chr10_-_80998174 0.89 ENSMUST00000118465.1
guanine nucleotide binding protein (G protein), gamma 7
chr4_-_62470868 0.89 ENSMUST00000135811.1
ENSMUST00000120095.1
ENSMUST00000030087.7
ENSMUST00000107452.1
ENSMUST00000155522.1
WD repeat domain 31
chr10_-_127195709 0.89 ENSMUST00000038217.7
ENSMUST00000130855.1
ENSMUST00000116229.1
ENSMUST00000144322.1
deltex 3 homolog (Drosophila)
chr5_-_112251137 0.88 ENSMUST00000112383.1
crystallin, beta A4
chr9_-_121495678 0.87 ENSMUST00000035120.4
cholecystokinin
chr3_+_146404844 0.87 ENSMUST00000106149.1
synovial sarcoma, X breakpoint 2 interacting protein
chr13_+_20794119 0.86 ENSMUST00000021757.3
acyloxyacyl hydrolase
chr7_-_27542745 0.85 ENSMUST00000150964.1
phospholipase D family, member 3
chr5_+_66745835 0.84 ENSMUST00000101164.4
ENSMUST00000118242.1
ENSMUST00000119854.1
ENSMUST00000117601.1
LIM and calponin homology domains 1
chr7_+_120843551 0.84 ENSMUST00000106489.1
ENSMUST00000143279.1
eukaryotic elongation factor-2 kinase
chr3_-_121532271 0.83 ENSMUST00000039197.7
solute carrier family 44, member 3
chr2_-_45112890 0.82 ENSMUST00000076836.6
zinc finger E-box binding homeobox 2
chr11_+_68503019 0.82 ENSMUST00000102613.1
ENSMUST00000060441.6
phosphoinositide-3-kinase, regulatory subunit 6
chr9_-_123632545 0.81 ENSMUST00000026273.8
solute carrier family 6 (neurotransmitter transporter), member 20B
chr8_-_70766654 0.81 ENSMUST00000034299.5
interferon gamma inducible protein 30
chr9_-_60141220 0.81 ENSMUST00000034829.5
thrombospondin, type I, domain containing 4
chr8_-_105637350 0.80 ENSMUST00000182863.1
predicted gene 5914
chr6_-_135254326 0.76 ENSMUST00000111911.2
ENSMUST00000111910.2
germ cell-specific gene 1
chr4_+_135911808 0.74 ENSMUST00000068830.3
cannabinoid receptor 2 (macrophage)
chr12_+_55124528 0.74 ENSMUST00000177768.1
family with sequence similarity 177, member A
chr11_+_120458093 0.73 ENSMUST00000058370.7
ENSMUST00000175970.1
ENSMUST00000176120.1
coiled-coil domain containing 137
chr2_+_105127200 0.72 ENSMUST00000139585.1
Wilms tumor 1 homolog
chr8_+_121730563 0.72 ENSMUST00000026357.5
junctophilin 3
chr8_-_120589304 0.71 ENSMUST00000034278.5
GINS complex subunit 2 (Psf2 homolog)
chr7_+_100227638 0.71 ENSMUST00000054436.8
phosphoglucomutase 2-like 1
chr7_+_25627604 0.68 ENSMUST00000076034.6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr15_-_79834224 0.67 ENSMUST00000109623.1
ENSMUST00000109625.1
ENSMUST00000023060.6
ENSMUST00000089299.5
chromobox 6
neuronal pentraxin chromo domain
chr2_+_76406529 0.66 ENSMUST00000111929.1
ENSMUST00000077972.4
ENSMUST00000111930.2
oxysterol binding protein-like 6
chr4_-_59783800 0.66 ENSMUST00000107526.1
ENSMUST00000095063.4
INTS3 and NABP interacting protein
chr14_-_61037937 0.66 ENSMUST00000111236.2
tumor necrosis factor receptor superfamily, member 19
chr3_-_54735001 0.65 ENSMUST00000153224.1
exosome component 8
chr7_+_120842824 0.64 ENSMUST00000047875.8
eukaryotic elongation factor-2 kinase
chr13_+_49682191 0.64 ENSMUST00000172254.1
isoleucine-tRNA synthetase
chr16_+_35770382 0.63 ENSMUST00000023555.4
Hspb associated protein 1
chr4_-_153975038 0.63 ENSMUST00000030893.2
DNA fragmentation factor, beta subunit
chrX_-_150589844 0.63 ENSMUST00000112725.1
ENSMUST00000112720.1
apurinic/apyrimidinic endonuclease 2
chr2_+_156475803 0.62 ENSMUST00000029155.8
erythrocyte protein band 4.1-like 1
chr4_+_11558914 0.62 ENSMUST00000178703.1
ENSMUST00000095145.5
ENSMUST00000108306.2
ENSMUST00000070755.6
RAD54 homolog B (S. cerevisiae)
chr5_-_53707532 0.62 ENSMUST00000031093.3
cholecystokinin A receptor
chr3_+_103074009 0.62 ENSMUST00000090715.6
adenosine monophosphate deaminase 1
chr5_-_137611372 0.62 ENSMUST00000054564.6
procollagen C-endopeptidase enhancer protein
chr2_+_156475844 0.62 ENSMUST00000103135.1
erythrocyte protein band 4.1-like 1
chr19_-_5894100 0.61 ENSMUST00000055911.4
tigger transposable element derived 3
chr2_+_118388615 0.60 ENSMUST00000005233.5
ENSMUST00000110877.1
eukaryotic translation initiation factor 2 alpha kinase 4
chr5_-_134688568 0.60 ENSMUST00000015137.3
LIM-domain containing, protein kinase
chr19_-_29367294 0.59 ENSMUST00000138051.1
plasminogen receptor, C-terminal lysine transmembrane protein
chr4_-_16013796 0.59 ENSMUST00000149891.1
oxidative stress induced growth inhibitor family member 2
chr4_-_156059414 0.58 ENSMUST00000184348.1
tubulin tyrosine ligase-like family, member 10
chr5_+_114130386 0.58 ENSMUST00000031587.6
uracil DNA glycosylase
chr17_+_35533194 0.57 ENSMUST00000025273.8
psoriasis susceptibility 1 candidate 2 (human)
chr1_+_134037490 0.56 ENSMUST00000162779.1
fibromodulin
chr4_-_142239356 0.56 ENSMUST00000036476.3
kazrin, periplakin interacting protein
chr5_-_140565060 0.55 ENSMUST00000042993.6
galectin-related inter-fiber protein
chr5_-_137611429 0.55 ENSMUST00000031731.7
procollagen C-endopeptidase enhancer protein
chr7_-_25297967 0.54 ENSMUST00000005583.5
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr17_-_47924460 0.53 ENSMUST00000113262.1
forkhead box P4
chr11_-_100135928 0.52 ENSMUST00000107411.2
keratin 15
chr3_+_146121655 0.52 ENSMUST00000039450.4
mucolipin 3
chr15_+_98634743 0.52 ENSMUST00000003442.7
calcium channel, voltage-dependent, beta 3 subunit
chr7_-_25369712 0.51 ENSMUST00000167591.1
ENSMUST00000076276.3
cornifelin
chr17_-_23740301 0.51 ENSMUST00000024702.3
progestin and adipoQ receptor family member IV
chr5_-_141000590 0.50 ENSMUST00000085786.5
caspase recruitment domain family, member 11
chr11_+_75651504 0.50 ENSMUST00000069057.6
myosin IC
chr4_+_140701466 0.50 ENSMUST00000038893.5
ENSMUST00000138808.1
regulator of chromosome condensation 2
chr15_+_34495302 0.48 ENSMUST00000052290.7
ENSMUST00000079028.5
processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)
chr3_-_136326038 0.47 ENSMUST00000041577.8
B cell scaffold protein with ankyrin repeats 1
chr3_-_37724321 0.47 ENSMUST00000108105.1
ENSMUST00000079755.4
ENSMUST00000099128.1
predicted gene 5148
chr10_+_97565436 0.47 ENSMUST00000038160.4
lumican
chr5_+_138995038 0.47 ENSMUST00000100518.2
RIKEN cDNA 6330403L08 gene
chr4_-_57300751 0.46 ENSMUST00000151964.1
protein tyrosine phosphatase, non-receptor type 3
chr3_-_108210438 0.46 ENSMUST00000117784.1
ENSMUST00000119650.1
ENSMUST00000117409.1
ataxin 7-like 2
chr14_+_63436394 0.46 ENSMUST00000121288.1
family with sequence similarity 167, member A
chr2_+_24962400 0.45 ENSMUST00000028351.3
diphthamine biosynethesis 7
chr17_-_47924400 0.45 ENSMUST00000113263.1
ENSMUST00000097311.2
forkhead box P4
chr11_+_115974930 0.45 ENSMUST00000106460.2
integrin beta 4
chr4_-_154097105 0.44 ENSMUST00000105643.1
ENSMUST00000133533.1
ENSMUST00000097762.4
transformation related protein 73
chr18_+_11633276 0.44 ENSMUST00000115861.2
retinoblastoma binding protein 8
chr2_-_39005574 0.43 ENSMUST00000080861.5
ribosomal protein L35
chr11_+_50376982 0.43 ENSMUST00000109142.1
heterogeneous nuclear ribonucleoprotein H1
chrX_+_155262443 0.43 ENSMUST00000026324.9
acyl-CoA thioesterase 9
chr19_+_29367447 0.42 ENSMUST00000016640.7
CD274 antigen
chrX_+_6577259 0.42 ENSMUST00000089520.2
shroom family member 4
chr8_+_70594466 0.42 ENSMUST00000019283.9
myo-inositol 1-phosphate synthase A1
chr18_+_3507945 0.41 ENSMUST00000025075.1
BMP and activin membrane-bound inhibitor
chr8_+_124023394 0.40 ENSMUST00000034457.8
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr3_-_146685592 0.40 ENSMUST00000125965.1
sterile alpha motif domain containing 13
chr15_+_12205009 0.39 ENSMUST00000038172.8
myotubularin related protein 12
chr17_-_47924635 0.39 ENSMUST00000113265.1
forkhead box P4
chr15_-_85821733 0.39 ENSMUST00000064370.4
polycystic kidney disease (polycystin) and REJ (sperm receptor for egg jelly homolog, sea urchin)
chrX_+_20425688 0.38 ENSMUST00000115384.2
PHD finger protein 16
chr6_-_118562226 0.36 ENSMUST00000112830.1
ankyrin repeat domain 26
chr3_+_90654253 0.36 ENSMUST00000079286.2
S100 calcium binding protein A7A
chr16_-_19200350 0.36 ENSMUST00000103749.2
immunoglobulin lambda constant 2
chr17_-_63863791 0.36 ENSMUST00000050753.3
RIKEN cDNA A930002H24 gene
chr17_-_12992227 0.34 ENSMUST00000007007.7
Wilms' tumour 1-associating protein
chr2_-_45113216 0.34 ENSMUST00000124942.1
zinc finger E-box binding homeobox 2
chr15_+_102518714 0.33 ENSMUST00000146756.1
ENSMUST00000142194.1
TAR (HIV) RNA binding protein 2
chr3_+_98382438 0.32 ENSMUST00000056096.8
zinc finger protein 697
chr2_-_9878580 0.32 ENSMUST00000102976.3
GATA binding protein 3
chr17_-_12992188 0.32 ENSMUST00000159986.1
Wilms' tumour 1-associating protein
chr6_-_135254170 0.31 ENSMUST00000111909.1
germ cell-specific gene 1
chr5_-_123012874 0.31 ENSMUST00000172729.1
lysine (K)-specific demethylase 2B
chr3_-_104777483 0.29 ENSMUST00000139783.1
family with sequence similarity 19, member A3
chr9_-_98033181 0.29 ENSMUST00000035027.6
calsyntenin 2
chr17_-_49564262 0.29 ENSMUST00000057610.6
dishevelled associated activator of morphogenesis 2
chr11_-_62392605 0.27 ENSMUST00000151498.2
ENSMUST00000159069.1
nuclear receptor co-repressor 1
chr9_+_109931774 0.27 ENSMUST00000169851.2
microtubule-associated protein 4
chr19_+_55894508 0.27 ENSMUST00000142291.1
transcription factor 7 like 2, T cell specific, HMG box
chr3_+_121531653 0.27 ENSMUST00000181070.1
RIKEN cDNA A530020G20 gene
chr6_-_78468863 0.26 ENSMUST00000032089.2
regenerating islet-derived 3 gamma
chr11_+_65162132 0.26 ENSMUST00000181156.1
RIKEN cDNA B430202K04 gene
chr4_+_62408770 0.25 ENSMUST00000084524.3
PRP4 pre-mRNA processing factor 4 homolog (yeast)
chr11_-_95514570 0.25 ENSMUST00000058866.7
neurexophilin 3
chr16_+_36934976 0.25 ENSMUST00000023531.8
hematopoietic cell specific Lyn substrate 1
chr2_+_110721340 0.25 ENSMUST00000111016.2
mucin 15
chr2_+_180581220 0.24 ENSMUST00000169630.1
MRG/MORF4L binding protein
chr5_+_135670027 0.23 ENSMUST00000153500.1
P450 (cytochrome) oxidoreductase
chr8_-_13105431 0.23 ENSMUST00000164416.1
PCI domain containing 2
chr1_+_55406163 0.23 ENSMUST00000042986.8
phospholipase C-like 1
chr11_-_72361837 0.23 ENSMUST00000108503.2
tektin 1
chr8_+_13105715 0.22 ENSMUST00000121426.1
cullin 4A

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp784

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.9 3.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.8 2.5 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.8 2.3 GO:0010751 regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763)
0.7 2.1 GO:0002358 B cell homeostatic proliferation(GO:0002358)
0.7 2.0 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.5 2.6 GO:0070103 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.5 3.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.5 1.4 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.5 3.6 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.5 1.8 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.4 1.3 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.4 2.0 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.4 2.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.4 6.6 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 1.3 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.3 1.3 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.3 1.2 GO:0045399 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425) cellular response to molecule of fungal origin(GO:0071226)
0.3 1.1 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.3 1.3 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.2 0.7 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.2 1.4 GO:1903367 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.2 0.7 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.2 1.1 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.2 0.6 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.2 0.6 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.2 0.6 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.2 1.8 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.2 2.2 GO:0071294 cellular response to zinc ion(GO:0071294)
0.2 0.6 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.2 1.4 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.2 1.4 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.2 1.0 GO:0021636 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.2 0.7 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 2.7 GO:0051382 kinetochore assembly(GO:0051382)
0.2 0.5 GO:0016078 tRNA catabolic process(GO:0016078)
0.1 3.9 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 1.4 GO:0036376 sodium ion export from cell(GO:0036376)
0.1 1.3 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.1 3.3 GO:0097186 amelogenesis(GO:0097186)
0.1 1.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 2.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.8 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 1.2 GO:1901249 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.1 0.4 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.3 GO:0061290 cell-cell signaling involved in kidney development(GO:0060995) cell proliferation involved in mesonephros development(GO:0061209) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.1 0.6 GO:0018094 protein polyglycylation(GO:0018094)
0.1 1.5 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 0.4 GO:1902167 cerebrospinal fluid secretion(GO:0033326) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.1 1.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 0.9 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.7 GO:0045759 negative regulation of action potential(GO:0045759)
0.1 0.3 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.1 0.9 GO:0051901 negative regulation of appetite(GO:0032099) positive regulation of mitochondrial depolarization(GO:0051901)
0.1 0.6 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.2 GO:0071033 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.1 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.1 0.6 GO:0032264 IMP salvage(GO:0032264)
0.1 0.3 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.1 0.5 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 0.9 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 0.3 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.3 GO:1903978 regulation of microglial cell activation(GO:1903978)
0.1 1.3 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.1 0.2 GO:0090346 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.1 0.4 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 1.9 GO:0000154 rRNA modification(GO:0000154)
0.1 1.2 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.1 GO:0038091 cell migration involved in vasculogenesis(GO:0035441) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.0 0.2 GO:0015786 UDP-glucose transport(GO:0015786)
0.0 1.4 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0051715 cytolysis in other organism(GO:0051715)
0.0 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.5 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.3 GO:0070970 interleukin-2 secretion(GO:0070970)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.5 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.0 1.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 1.1 GO:0031424 keratinization(GO:0031424)
0.0 0.7 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.3 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 0.4 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 2.6 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 0.9 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.6 GO:0051444 negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.0 0.6 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 1.2 GO:0051567 histone H3-K9 methylation(GO:0051567)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 2.8 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 1.8 GO:0045582 positive regulation of T cell differentiation(GO:0045582)
0.0 1.1 GO:0048536 spleen development(GO:0048536)
0.0 0.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.4 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.0 1.1 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.0 0.4 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.6 GO:0006284 base-excision repair(GO:0006284)
0.0 1.7 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.7 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.7 2.1 GO:1990423 RZZ complex(GO:1990423)
0.7 3.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 2.0 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.4 3.9 GO:0008290 F-actin capping protein complex(GO:0008290)
0.3 1.4 GO:0032280 symmetric synapse(GO:0032280)
0.3 1.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.3 1.9 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 0.7 GO:0000811 GINS complex(GO:0000811)
0.2 2.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 0.8 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 3.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 0.9 GO:0036396 MIS complex(GO:0036396)
0.2 1.2 GO:0019815 B cell receptor complex(GO:0019815)
0.2 6.1 GO:0035371 microtubule plus-end(GO:0035371)
0.2 1.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.7 GO:0070876 SOSS complex(GO:0070876)
0.1 0.5 GO:0045160 myosin I complex(GO:0045160)
0.1 3.2 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.3 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.7 GO:0030314 junctional membrane complex(GO:0030314)
0.1 3.6 GO:0002102 podosome(GO:0002102)
0.1 2.0 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.9 GO:0043203 axon hillock(GO:0043203)
0.1 2.8 GO:0032590 dendrite membrane(GO:0032590)
0.1 0.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 1.3 GO:0030673 axolemma(GO:0030673)
0.0 0.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.0 1.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.5 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.6 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.8 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 2.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)
0.0 2.7 GO:0000776 kinetochore(GO:0000776)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.0 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 1.8 GO:0005884 actin filament(GO:0005884)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.5 3.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.5 2.7 GO:0043515 kinetochore binding(GO:0043515)
0.5 1.5 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.5 1.4 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.4 2.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.4 2.0 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.3 2.4 GO:0001515 opioid peptide activity(GO:0001515)
0.3 1.4 GO:0038132 neuregulin binding(GO:0038132)
0.3 1.6 GO:0004977 melanocortin receptor activity(GO:0004977)
0.3 1.3 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.3 2.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 0.7 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.2 1.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 0.6 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.2 0.6 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.2 0.6 GO:0070737 protein-glycine ligase activity, elongating(GO:0070737)
0.2 0.7 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.2 1.1 GO:1902282 phosphorelay sensor kinase activity(GO:0000155) voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.2 0.5 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.2 1.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.2 1.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 0.5 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.2 0.6 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.6 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 2.3 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 1.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 4.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 8.7 GO:0030507 spectrin binding(GO:0030507)
0.1 1.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.7 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.7 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 2.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.6 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.4 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 2.1 GO:0080025 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.2 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.1 0.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 1.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 2.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.7 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.0 1.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.8 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 1.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.9 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 1.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.8 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 1.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 3.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.7 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.2 GO:0019894 kinesin binding(GO:0019894)
0.0 2.4 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.6 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 1.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.5 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 2.2 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 0.7 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.4 PID AURORA A PATHWAY Aurora A signaling
0.1 3.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 3.6 PID REELIN PATHWAY Reelin signaling pathway
0.1 1.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.8 PID EPO PATHWAY EPO signaling pathway
0.0 2.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.8 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.6 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 3.6 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 1.5 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 0.7 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 5.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.9 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 6.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 2.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.9 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.4 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 3.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.8 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.5 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.1 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins