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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for AGCAGCG

Z-value: 0.46

Motif logo

logo of

miRNA associated with seed AGCAGCG

NamemiRBASE accession
mmu-miR-503-5p
MIMAT0003188

Activity profile of AGCAGCG motif

Sorted Z-values of AGCAGCG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_114131229 1.13 ENSMUST00000032451.7
Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr7_-_38107490 0.97 ENSMUST00000108023.3
Ccne1
cyclin E1
chr2_-_165473187 0.84 ENSMUST00000029208.8
ENSMUST00000109279.2
Slc13a3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
chr6_-_91411341 0.51 ENSMUST00000032180.6
Wnt7a
wingless-related MMTV integration site 7A
chr9_-_61946768 0.46 ENSMUST00000034815.7
Kif23
kinesin family member 23
chr9_-_36726374 0.45 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
Chek1
checkpoint kinase 1
chr11_-_87108656 0.37 ENSMUST00000051395.8
Prr11
proline rich 11
chr1_-_98095596 0.37 ENSMUST00000058762.8
ENSMUST00000097625.3
Pam
peptidylglycine alpha-amidating monooxygenase
chr19_+_4711153 0.33 ENSMUST00000008991.6
Sptbn2
spectrin beta, non-erythrocytic 2
chr1_-_152090308 0.33 ENSMUST00000044581.7
1700025G04Rik
RIKEN cDNA 1700025G04 gene
chr7_+_67952817 0.32 ENSMUST00000005671.8
Igf1r
insulin-like growth factor I receptor
chrX_-_48034842 0.31 ENSMUST00000039026.7
Apln
apelin
chr7_+_110122299 0.30 ENSMUST00000033326.8
Wee1
WEE 1 homolog 1 (S. pombe)
chr17_-_46629420 0.30 ENSMUST00000044442.8
Ptk7
PTK7 protein tyrosine kinase 7
chr17_-_31855782 0.30 ENSMUST00000024839.4
Sik1
salt inducible kinase 1
chr5_-_99252839 0.30 ENSMUST00000168092.1
ENSMUST00000031276.8
Rasgef1b
RasGEF domain family, member 1B
chr2_+_179442427 0.29 ENSMUST00000000314.6
Cdh4
cadherin 4
chr10_+_13090788 0.29 ENSMUST00000121646.1
ENSMUST00000121325.1
ENSMUST00000121766.1
Plagl1
pleiomorphic adenoma gene-like 1
chr5_+_47984793 0.25 ENSMUST00000170109.2
ENSMUST00000174421.1
ENSMUST00000173702.1
ENSMUST00000173107.1
Slit2
slit homolog 2 (Drosophila)
chr1_-_21961581 0.23 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
Kcnq5
potassium voltage-gated channel, subfamily Q, member 5
chr4_+_139574697 0.23 ENSMUST00000174078.1
Iffo2
intermediate filament family orphan 2
chr4_+_114406717 0.23 ENSMUST00000094894.3
Trabd2b
TraB domain containing 2B
chr5_-_89883321 0.21 ENSMUST00000163159.1
ENSMUST00000061427.5
Adamts3
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3
chr8_+_88521344 0.21 ENSMUST00000034086.5
Nkd1
naked cuticle 1 homolog (Drosophila)
chr7_+_18925863 0.21 ENSMUST00000172835.1
ENSMUST00000032571.8
Nova2
neuro-oncological ventral antigen 2
chr4_-_155222535 0.21 ENSMUST00000084103.3
ENSMUST00000030917.5
Ski
ski sarcoma viral oncogene homolog (avian)
chr14_-_31577318 0.21 ENSMUST00000112027.2
Colq
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr2_+_68117713 0.20 ENSMUST00000112346.2
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr10_-_29535857 0.20 ENSMUST00000092623.3
Rspo3
R-spondin 3 homolog (Xenopus laevis)
chr8_-_77724426 0.20 ENSMUST00000034029.7
Ednra
endothelin receptor type A
chr14_+_75016027 0.19 ENSMUST00000036072.7
5031414D18Rik
RIKEN cDNA 5031414D18 gene
chr15_+_103240405 0.19 ENSMUST00000036004.9
ENSMUST00000087351.7
Hnrnpa1
heterogeneous nuclear ribonucleoprotein A1
chr5_+_88886809 0.19 ENSMUST00000148750.1
Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr8_+_83900096 0.19 ENSMUST00000141158.1
Lphn1
latrophilin 1
chr11_-_119086221 0.17 ENSMUST00000026665.7
Cbx4
chromobox 4
chr5_+_113490447 0.15 ENSMUST00000094452.3
Wscd2
WSC domain containing 2
chr12_-_112829351 0.15 ENSMUST00000062092.5
Cdca4
cell division cycle associated 4
chr4_+_137277489 0.15 ENSMUST00000045747.4
Wnt4
wingless-related MMTV integration site 4
chr4_+_43875524 0.15 ENSMUST00000030198.6
Reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr13_+_47122719 0.15 ENSMUST00000068891.4
Rnf144b
ring finger protein 144B
chr14_+_55854115 0.14 ENSMUST00000168479.1
Nynrin
NYN domain and retroviral integrase containing
chr1_-_37541003 0.14 ENSMUST00000151952.1
Mgat4a
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr1_-_135585314 0.14 ENSMUST00000040599.8
ENSMUST00000067414.6
Nav1
neuron navigator 1
chr10_-_127060163 0.14 ENSMUST00000040307.5
March9
membrane-associated ring finger (C3HC4) 9
chr5_-_93045022 0.14 ENSMUST00000061328.5
Sowahb
sosondowah ankyrin repeat domain family member B
chr9_-_53975246 0.14 ENSMUST00000048409.7
Elmod1
ELMO/CED-12 domain containing 1
chr4_+_65124174 0.13 ENSMUST00000084501.3
Pappa
pregnancy-associated plasma protein A
chr19_+_45363734 0.13 ENSMUST00000065601.5
ENSMUST00000111936.2
Btrc
beta-transducin repeat containing protein
chr3_+_98382438 0.11 ENSMUST00000056096.8
Zfp697
zinc finger protein 697
chr8_-_86885222 0.11 ENSMUST00000034074.7
N4bp1
NEDD4 binding protein 1
chr9_-_108190352 0.11 ENSMUST00000035208.7
Bsn
bassoon
chr8_-_120589304 0.11 ENSMUST00000034278.5
Gins2
GINS complex subunit 2 (Psf2 homolog)
chr9_-_58159201 0.11 ENSMUST00000041477.7
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr1_-_106714217 0.11 ENSMUST00000112751.1
Bcl2
B cell leukemia/lymphoma 2
chr4_-_141790891 0.11 ENSMUST00000038014.4
ENSMUST00000153880.1
Dnajc16
DnaJ (Hsp40) homolog, subfamily C, member 16
chr15_-_9529868 0.10 ENSMUST00000003981.4
Il7r
interleukin 7 receptor
chr4_+_115839192 0.10 ENSMUST00000019677.5
ENSMUST00000144427.1
ENSMUST00000106513.3
ENSMUST00000130819.1
ENSMUST00000151203.1
ENSMUST00000140315.1
Mknk1
MAP kinase-interacting serine/threonine kinase 1
chr1_+_86045863 0.10 ENSMUST00000165824.1
2810459M11Rik
RIKEN cDNA 2810459M11 gene
chr7_-_118491912 0.09 ENSMUST00000178344.1
Itpripl2
inositol 1,4,5-triphosphate receptor interacting protein-like 2
chr14_-_65098031 0.09 ENSMUST00000022550.7
Extl3
exostoses (multiple)-like 3
chr6_-_127151044 0.09 ENSMUST00000000188.8
Ccnd2
cyclin D2
chr13_-_101768154 0.09 ENSMUST00000055518.6
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr19_+_10688744 0.09 ENSMUST00000087951.5
Vps37c
vacuolar protein sorting 37C (yeast)
chr10_+_128411616 0.08 ENSMUST00000096386.5
ENSMUST00000171342.1
Rnf41
ring finger protein 41
chr5_-_5514730 0.08 ENSMUST00000115445.1
ENSMUST00000179804.1
ENSMUST00000125110.1
ENSMUST00000115446.1
Cldn12
claudin 12
chr15_+_84923383 0.08 ENSMUST00000165443.2
Nup50
nucleoporin 50
chr11_-_63922257 0.08 ENSMUST00000094103.3
Hs3st3b1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr6_+_47877204 0.08 ENSMUST00000061890.7
Zfp282
zinc finger protein 282
chr8_+_22476700 0.07 ENSMUST00000067786.7
Slc20a2
solute carrier family 20, member 2
chr17_+_47505117 0.07 ENSMUST00000183044.1
ENSMUST00000037333.10
Ccnd3
cyclin D3
chr13_+_44731265 0.07 ENSMUST00000173246.1
Jarid2
jumonji, AT rich interactive domain 2
chr2_-_160872552 0.07 ENSMUST00000103111.2
Zhx3
zinc fingers and homeoboxes 3
chr8_-_122699066 0.07 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr9_+_43744399 0.06 ENSMUST00000034510.7
Pvrl1
poliovirus receptor-related 1
chr1_+_60746358 0.06 ENSMUST00000027165.2
Cd28
CD28 antigen
chr12_-_108003594 0.05 ENSMUST00000066060.4
Bcl11b
B cell leukemia/lymphoma 11B
chr8_+_105900421 0.05 ENSMUST00000049699.8
Pskh1
protein serine kinase H1
chr4_+_101419277 0.05 ENSMUST00000102780.1
ENSMUST00000106946.1
ENSMUST00000106945.1
Ak4
adenylate kinase 4
chr7_-_97738222 0.04 ENSMUST00000084986.6
Aqp11
aquaporin 11
chr13_-_103764502 0.04 ENSMUST00000074616.5
Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr2_-_30124454 0.04 ENSMUST00000044751.8
Zer1
zyg-11 related, cell cycle regulator
chr15_-_103239812 0.04 ENSMUST00000118152.1
Cbx5
chromobox 5
chr3_+_58415689 0.03 ENSMUST00000099090.2
Tsc22d2
TSC22 domain family, member 2
chr1_-_75479271 0.03 ENSMUST00000079205.7
ENSMUST00000094818.2
Chpf
chondroitin polymerizing factor
chr4_-_136835843 0.03 ENSMUST00000105846.2
ENSMUST00000059287.7
ENSMUST00000105845.2
Ephb2
Eph receptor B2
chr11_+_106036867 0.03 ENSMUST00000058438.8
Dcaf7
DDB1 and CUL4 associated factor 7
chr5_-_144965793 0.03 ENSMUST00000110677.1
ENSMUST00000085684.4
ENSMUST00000100461.2
Smurf1
SMAD specific E3 ubiquitin protein ligase 1
chr19_-_19001099 0.03 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb
RAR-related orphan receptor beta
chr10_+_127739516 0.02 ENSMUST00000054287.7
Zbtb39
zinc finger and BTB domain containing 39
chrX_+_36328353 0.02 ENSMUST00000016383.3
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr7_+_101108768 0.02 ENSMUST00000098250.3
ENSMUST00000032931.7
Fchsd2
FCH and double SH3 domains 2
chr2_-_39065438 0.02 ENSMUST00000112850.2
Golga1
golgi autoantigen, golgin subfamily a, 1
chr16_-_46010212 0.02 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr1_+_64690443 0.01 ENSMUST00000114077.1
Ccnyl1
cyclin Y-like 1
chr5_-_146795002 0.01 ENSMUST00000085614.5
Usp12
ubiquitin specific peptidase 12
chr11_+_107547925 0.01 ENSMUST00000100305.1
ENSMUST00000075012.1
ENSMUST00000106746.1
Helz
helicase with zinc finger domain
chr15_+_25984359 0.01 ENSMUST00000061875.6
Zfp622
zinc finger protein 622
chr7_+_122067164 0.01 ENSMUST00000033158.4
Ubfd1
ubiquitin family domain containing 1
chr8_+_106935720 0.01 ENSMUST00000047425.3
Sntb2
syntrophin, basic 2
chr19_-_60581013 0.01 ENSMUST00000111460.3
ENSMUST00000081790.7
ENSMUST00000166712.1
Cacul1
CDK2 associated, cullin domain 1
chr13_+_49421229 0.01 ENSMUST00000021817.8
Ippk
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr19_+_8953826 0.00 ENSMUST00000096239.5
Tut1
terminal uridylyl transferase 1, U6 snRNA-specific
chr11_-_70669283 0.00 ENSMUST00000129434.1
ENSMUST00000018431.6
Spag7
sperm associated antigen 7

Network of associatons between targets according to the STRING database.

First level regulatory network of AGCAGCG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0015744 succinate transport(GO:0015744)
0.2 0.5 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.3 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.5 GO:0060066 oviduct development(GO:0060066)
0.1 0.3 GO:0050924 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 0.3 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.2 GO:0072034 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) renal vesicle induction(GO:0072034) negative regulation of male gonad development(GO:2000019)
0.1 0.5 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.3 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.4 GO:0031179 peptide modification(GO:0031179)
0.0 0.1 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.2 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.2 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.0 0.2 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 1.1 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0006808 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) regulation of cellular pH reduction(GO:0032847)
0.0 0.2 GO:0018158 protein oxidation(GO:0018158)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.2 GO:0042482 artery smooth muscle contraction(GO:0014824) positive regulation of odontogenesis(GO:0042482)
0.0 0.3 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.0 GO:0072014 proximal tubule development(GO:0072014)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 1.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.2 1.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 0.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.3 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.1 0.4 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.4 GO:0043559 insulin binding(GO:0043559)
0.0 0.3 GO:0048495 GTPase inhibitor activity(GO:0005095) Roundabout binding(GO:0048495)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.0 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling