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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Creb1

Z-value: 2.19

Motif logo

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Transcription factors associated with Creb1

Gene Symbol Gene ID Gene Info
Creb1
ENSMUSG00000025958.8 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Creb1mm10_v2_chr1_+_64532790_64532815-0.115.4e-01Click!

Activity profile of Creb1 motif

Sorted Z-values of Creb1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_55099417 5.08 ENSMUST00000061856.5
Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
chr1_+_185363076 3.19 ENSMUST00000046514.7
Eprs
glutamyl-prolyl-tRNA synthetase
chr12_-_4907705 2.84 ENSMUST00000020962.5
Ubxn2a
UBX domain protein 2A
chr10_+_62920630 2.78 ENSMUST00000044977.3
Slc25a16
solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
chr12_+_108334341 2.61 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr13_-_29984219 2.58 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr14_-_59597836 2.46 ENSMUST00000167100.1
ENSMUST00000022555.4
ENSMUST00000056997.7
ENSMUST00000171683.1
Cdadc1
cytidine and dCMP deaminase domain containing 1
chr10_+_62920648 2.36 ENSMUST00000144459.1
Slc25a16
solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
chr12_-_4907229 2.34 ENSMUST00000142867.1
Ubxn2a
UBX domain protein 2A
chr11_-_86807624 2.27 ENSMUST00000018569.7
Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr8_+_40511769 2.24 ENSMUST00000098817.2
Vps37a
vacuolar protein sorting 37A (yeast)
chr8_+_3621529 2.03 ENSMUST00000156380.2
Pet100
PET100 homolog (S. cerevisiae)
chr11_-_83302586 2.01 ENSMUST00000176374.1
Pex12
peroxisomal biogenesis factor 12
chr13_+_58402546 1.97 ENSMUST00000042450.8
Rmi1
RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)
chrX_-_56598069 1.95 ENSMUST00000059899.2
Mmgt1
membrane magnesium transporter 1
chr1_+_180851131 1.91 ENSMUST00000038091.6
Sde2
SDE2 telomere maintenance homolog (S. pombe)
chr12_+_33429605 1.88 ENSMUST00000020877.7
Twistnb
TWIST neighbor
chr1_+_78657825 1.87 ENSMUST00000035779.8
Acsl3
acyl-CoA synthetase long-chain family member 3
chr12_+_116281180 1.87 ENSMUST00000100986.2
Esyt2
extended synaptotagmin-like protein 2
chr12_+_28751798 1.81 ENSMUST00000035657.7
Tssc1
tumor suppressing subtransferable candidate 1
chr10_+_7792891 1.75 ENSMUST00000015901.4
Ppil4
peptidylprolyl isomerase (cyclophilin)-like 4
chr12_-_57546121 1.67 ENSMUST00000044380.6
Foxa1
forkhead box A1
chr7_+_46796088 1.66 ENSMUST00000006774.4
ENSMUST00000165031.1
Gtf2h1
general transcription factor II H, polypeptide 1
chr1_+_43933980 1.62 ENSMUST00000087933.3
Tpp2
tripeptidyl peptidase II
chr18_+_9958147 1.58 ENSMUST00000025137.7
Thoc1
THO complex 1
chr5_-_112343010 1.56 ENSMUST00000146510.1
ENSMUST00000031289.6
Srrd
SRR1 domain containing
chr16_+_22857845 1.55 ENSMUST00000004574.7
ENSMUST00000178320.1
ENSMUST00000166487.2
Dnajb11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr10_+_44268328 1.51 ENSMUST00000039286.4
Atg5
autophagy related 5
chr8_-_22653406 1.51 ENSMUST00000033938.5
Polb
polymerase (DNA directed), beta
chr8_-_79711631 1.50 ENSMUST00000080536.6
Abce1
ATP-binding cassette, sub-family E (OABP), member 1
chr2_-_119156824 1.49 ENSMUST00000135419.1
ENSMUST00000129351.1
ENSMUST00000139519.1
ENSMUST00000094695.5
Rmdn3
regulator of microtubule dynamics 3
chr8_-_40511298 1.45 ENSMUST00000149992.1
Cnot7
CCR4-NOT transcription complex, subunit 7
chr1_+_78657874 1.42 ENSMUST00000134566.1
ENSMUST00000142704.1
ENSMUST00000053760.5
Acsl3
Utp14b
acyl-CoA synthetase long-chain family member 3
UTP14, U3 small nucleolar ribonucleoprotein, homolog B (yeast)
chr12_+_51377560 1.37 ENSMUST00000021335.5
Scfd1
Sec1 family domain containing 1
chr13_+_98263242 1.37 ENSMUST00000022164.8
ENSMUST00000150352.1
Ankra2
ankyrin repeat, family A (RFXANK-like), 2
chr14_-_31251194 1.36 ENSMUST00000022459.3
Phf7
PHD finger protein 7
chr2_+_144556229 1.33 ENSMUST00000143573.1
ENSMUST00000028916.8
ENSMUST00000155258.1
Sec23b
SEC23B (S. cerevisiae)
chr7_-_118533298 1.32 ENSMUST00000098090.3
ENSMUST00000032887.3
Coq7
demethyl-Q 7
chr4_-_149307506 1.31 ENSMUST00000055647.8
ENSMUST00000030806.5
ENSMUST00000060537.6
Kif1b
kinesin family member 1B
chr12_-_56535047 1.30 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr8_-_40511663 1.30 ENSMUST00000135269.1
ENSMUST00000034012.3
Cnot7
CCR4-NOT transcription complex, subunit 7
chr12_-_108179237 1.30 ENSMUST00000071095.7
Setd3
SET domain containing 3
chr12_-_101083653 1.30 ENSMUST00000048305.8
ENSMUST00000163095.1
Smek1
SMEK homolog 1, suppressor of mek1 (Dictyostelium)
chr9_-_96478660 1.29 ENSMUST00000057500.4
Rnf7
ring finger protein 7
chr8_+_60993189 1.28 ENSMUST00000034065.7
ENSMUST00000120689.1
Nek1
NIMA (never in mitosis gene a)-related expressed kinase 1
chr11_+_95384662 1.27 ENSMUST00000021243.7
ENSMUST00000146556.1
Slc35b1
solute carrier family 35, member B1
chr6_-_4086914 1.26 ENSMUST00000049166.4
Bet1
blocked early in transport 1 homolog (S. cerevisiae)
chr13_+_96542727 1.23 ENSMUST00000077672.4
ENSMUST00000109444.2
Col4a3bp
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chrX_+_71816758 1.23 ENSMUST00000114576.2
ENSMUST00000114575.3
Vma21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr9_-_96478596 1.22 ENSMUST00000071301.4
Rnf7
ring finger protein 7
chr9_-_53248106 1.20 ENSMUST00000065630.6
Ddx10
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr18_+_6765171 1.20 ENSMUST00000097680.5
Rab18
RAB18, member RAS oncogene family
chr1_-_134361933 1.18 ENSMUST00000049470.4
Tmem183a
transmembrane protein 183A
chr1_+_58973521 1.18 ENSMUST00000114296.1
ENSMUST00000027185.4
Stradb
STE20-related kinase adaptor beta
chr4_+_131843459 1.17 ENSMUST00000030742.4
ENSMUST00000137321.1
Mecr
mitochondrial trans-2-enoyl-CoA reductase
chr13_+_98263187 1.17 ENSMUST00000091356.3
ENSMUST00000123924.1
Ankra2
ankyrin repeat, family A (RFXANK-like), 2
chr15_-_96460838 1.16 ENSMUST00000047835.6
Scaf11
SR-related CTD-associated factor 11
chr3_+_138143483 1.16 ENSMUST00000162864.1
Trmt10a
tRNA methyltransferase 10A
chr5_-_65335597 1.14 ENSMUST00000172660.1
ENSMUST00000172732.1
ENSMUST00000031092.8
Rfc1
replication factor C (activator 1) 1
chr1_-_37430071 1.13 ENSMUST00000027286.6
Coa5
cytochrome C oxidase assembly factor 5
chr1_-_150392719 1.13 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
BC003331
cDNA sequence BC003331
chr4_-_40279389 1.13 ENSMUST00000108108.2
ENSMUST00000095128.3
Ndufb6
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6
chr15_+_36174010 1.12 ENSMUST00000180159.1
ENSMUST00000057177.6
Polr2k
polymerase (RNA) II (DNA directed) polypeptide K
chr3_-_107696462 1.10 ENSMUST00000029490.8
Ahcyl1
S-adenosylhomocysteine hydrolase-like 1
chr12_+_8208107 1.09 ENSMUST00000037383.5
ENSMUST00000169104.1
1110057K04Rik
RIKEN cDNA 1110057K04 gene
chr5_+_67260794 1.09 ENSMUST00000161369.1
Tmem33
transmembrane protein 33
chrX_-_74023745 1.08 ENSMUST00000114353.3
ENSMUST00000101458.2
Irak1
interleukin-1 receptor-associated kinase 1
chr19_+_8735808 1.08 ENSMUST00000049424.9
Wdr74
WD repeat domain 74
chr10_+_94688739 1.07 ENSMUST00000020212.4
Ccdc41
coiled-coil domain containing 41
chr13_-_96542479 1.07 ENSMUST00000022172.4
Polk
polymerase (DNA directed), kappa
chr14_+_54883377 1.07 ENSMUST00000022806.3
ENSMUST00000172844.1
ENSMUST00000133397.2
ENSMUST00000134077.1
Bcl2l2
Gm20521
BCL2-like 2
predicted gene 20521
chr17_+_46496753 1.06 ENSMUST00000046497.6
Dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr12_-_73286698 1.06 ENSMUST00000116420.2
Trmt5
TRM5 tRNA methyltransferase 5
chr16_+_43889936 1.05 ENSMUST00000151183.1
2610015P09Rik
RIKEN cDNA 2610015P09 gene
chr3_+_138143429 1.05 ENSMUST00000040321.6
Trmt10a
tRNA methyltransferase 10A
chr1_-_106796687 1.04 ENSMUST00000094646.5
Vps4b
vacuolar protein sorting 4b (yeast)
chr5_+_124439891 1.03 ENSMUST00000059580.4
Setd8
SET domain containing (lysine methyltransferase) 8
chr13_+_98263105 1.03 ENSMUST00000150916.1
Ankra2
ankyrin repeat, family A (RFXANK-like), 2
chr19_-_24961545 1.03 ENSMUST00000025815.8
Cbwd1
COBW domain containing 1
chr15_-_81399594 1.02 ENSMUST00000023039.8
St13
suppression of tumorigenicity 13
chr4_+_115737738 1.01 ENSMUST00000106525.2
Efcab14
EF-hand calcium binding domain 14
chr4_-_147904680 1.01 ENSMUST00000105716.2
ENSMUST00000105715.1
ENSMUST00000105714.1
ENSMUST00000030884.3
Mfn2
mitofusin 2
chr4_-_19708922 1.01 ENSMUST00000108246.2
Wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr4_-_14826582 1.00 ENSMUST00000117268.1
Otud6b
OTU domain containing 6B
chr9_-_122950922 1.00 ENSMUST00000118422.1
1110059G10Rik
RIKEN cDNA 1110059G10 gene
chr4_+_115737754 1.00 ENSMUST00000106522.2
Efcab14
EF-hand calcium binding domain 14
chr15_-_94589870 0.99 ENSMUST00000023087.6
ENSMUST00000152590.1
Twf1
twinfilin, actin-binding protein, homolog 1 (Drosophila)
chr3_-_127553233 0.98 ENSMUST00000029588.5
Larp7
La ribonucleoprotein domain family, member 7
chr16_-_97922582 0.98 ENSMUST00000170757.1
C2cd2
C2 calcium-dependent domain containing 2
chr1_-_150393024 0.97 ENSMUST00000097546.2
ENSMUST00000111913.2
BC003331
cDNA sequence BC003331
chr11_+_59202480 0.95 ENSMUST00000108786.1
ENSMUST00000108787.2
ENSMUST00000045697.5
ENSMUST00000108785.1
ENSMUST00000108784.3
Mrpl55
mitochondrial ribosomal protein L55
chr9_-_122950960 0.94 ENSMUST00000035154.3
1110059G10Rik
RIKEN cDNA 1110059G10 gene
chr13_-_58402533 0.94 ENSMUST00000176207.1
Hnrnpk
heterogeneous nuclear ribonucleoprotein K
chr7_-_110844350 0.92 ENSMUST00000177462.1
ENSMUST00000176746.1
ENSMUST00000177236.1
Rnf141
ring finger protein 141
chr12_-_56345862 0.92 ENSMUST00000021416.7
Mbip
MAP3K12 binding inhibitory protein 1
chr9_+_121710389 0.91 ENSMUST00000035113.9
Deb1
differentially expressed in B16F10 1
chr13_+_96542602 0.90 ENSMUST00000179226.1
Col4a3bp
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr10_+_82954344 0.90 ENSMUST00000095396.3
Gm4799
predicted gene 4799
chr11_-_115276973 0.90 ENSMUST00000021078.2
Fdxr
ferredoxin reductase
chr14_+_55745678 0.90 ENSMUST00000019441.8
Nop9
NOP9 nucleolar protein
chr5_+_24100578 0.90 ENSMUST00000030841.5
ENSMUST00000163409.1
Klhl7
kelch-like 7
chr5_+_38039224 0.90 ENSMUST00000031008.6
ENSMUST00000042146.8
ENSMUST00000154929.1
Stx18
syntaxin 18
chr1_+_53313622 0.89 ENSMUST00000027265.3
Osgepl1
O-sialoglycoprotein endopeptidase-like 1
chr5_-_74531619 0.88 ENSMUST00000113542.2
ENSMUST00000072857.6
ENSMUST00000121330.1
ENSMUST00000151474.1
Scfd2
Sec1 family domain containing 2
chr15_+_65787023 0.88 ENSMUST00000015146.9
ENSMUST00000173858.1
ENSMUST00000172756.1
ENSMUST00000174856.1
Efr3a
EFR3 homolog A (S. cerevisiae)
chr5_-_65335564 0.87 ENSMUST00000172780.1
Rfc1
replication factor C (activator 1) 1
chr16_+_22009471 0.87 ENSMUST00000023561.7
Senp2
SUMO/sentrin specific peptidase 2
chr10_-_30618337 0.87 ENSMUST00000019925.5
Hint3
histidine triad nucleotide binding protein 3
chr7_-_55962424 0.87 ENSMUST00000126604.1
ENSMUST00000117812.1
ENSMUST00000119201.1
Nipa2
non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)
chr1_-_106796609 0.85 ENSMUST00000112736.1
Vps4b
vacuolar protein sorting 4b (yeast)
chr7_-_55962466 0.85 ENSMUST00000032635.7
ENSMUST00000152649.1
Nipa2
non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)
chr17_-_27907706 0.85 ENSMUST00000025057.4
Taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr9_+_123113215 0.85 ENSMUST00000026891.4
Exosc7
exosome component 7
chr14_-_76110760 0.85 ENSMUST00000022585.3
Gpalpp1
GPALPP motifs containing 1
chr15_-_81400043 0.84 ENSMUST00000172107.1
ENSMUST00000169204.1
ENSMUST00000163382.1
St13
suppression of tumorigenicity 13
chr10_-_30618436 0.84 ENSMUST00000161074.1
Hint3
histidine triad nucleotide binding protein 3
chr5_+_48372363 0.84 ENSMUST00000030968.2
Pacrgl
PARK2 co-regulated-like
chr18_-_35498856 0.83 ENSMUST00000025215.8
Sil1
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr10_-_82764088 0.83 ENSMUST00000130911.1
Nfyb
nuclear transcription factor-Y beta
chr17_+_25184561 0.83 ENSMUST00000088307.3
BC003965
cDNA sequence BC003965
chr3_-_100685431 0.83 ENSMUST00000008907.7
Man1a2
mannosidase, alpha, class 1A, member 2
chr6_+_57703051 0.83 ENSMUST00000151042.1
Lancl2
LanC (bacterial lantibiotic synthetase component C)-like 2
chr19_+_5041337 0.82 ENSMUST00000116567.2
Brms1
breast cancer metastasis-suppressor 1
chr5_+_35583018 0.82 ENSMUST00000068947.7
ENSMUST00000114237.1
ENSMUST00000156125.1
ENSMUST00000068563.5
Acox3
acyl-Coenzyme A oxidase 3, pristanoyl
chr1_+_53313636 0.81 ENSMUST00000114484.1
Osgepl1
O-sialoglycoprotein endopeptidase-like 1
chr5_-_36748639 0.81 ENSMUST00000071949.3
Bloc1s4
biogenesis of organelles complex-1, subunit 4, cappuccino
chr2_-_34826187 0.81 ENSMUST00000113075.1
ENSMUST00000113080.2
ENSMUST00000091020.3
Fbxw2
F-box and WD-40 domain protein 2
chr6_+_114643106 0.80 ENSMUST00000169310.3
ENSMUST00000182169.1
ENSMUST00000183165.1
ENSMUST00000182098.1
ENSMUST00000182793.1
ENSMUST00000182902.1
ENSMUST00000182428.1
ENSMUST00000182035.1
Atg7
autophagy related 7
chr5_+_67260696 0.80 ENSMUST00000161233.1
ENSMUST00000160352.1
Tmem33
transmembrane protein 33
chrX_-_74023908 0.80 ENSMUST00000033769.8
ENSMUST00000114352.1
ENSMUST00000068286.5
ENSMUST00000114360.3
ENSMUST00000114354.3
Irak1
interleukin-1 receptor-associated kinase 1
chr4_+_59003121 0.80 ENSMUST00000095070.3
ENSMUST00000174664.1
Dnajc25
Gm20503
DnaJ (Hsp40) homolog, subfamily C, member 25
predicted gene 20503
chr9_+_64179289 0.79 ENSMUST00000034965.6
Snapc5
small nuclear RNA activating complex, polypeptide 5
chrX_-_20962005 0.79 ENSMUST00000123836.1
Uxt
ubiquitously expressed transcript
chr12_-_98901478 0.78 ENSMUST00000065716.6
Eml5
echinoderm microtubule associated protein like 5
chr5_-_76905463 0.78 ENSMUST00000146570.1
ENSMUST00000142450.1
ENSMUST00000120963.1
Aasdh
aminoadipate-semialdehyde dehydrogenase
chr3_+_138143846 0.78 ENSMUST00000159481.1
Trmt10a
tRNA methyltransferase 10A
chr6_-_86733268 0.78 ENSMUST00000001185.7
Gmcl1
germ cell-less homolog 1 (Drosophila)
chr10_-_127041513 0.78 ENSMUST00000116231.2
Mettl21b
methyltransferase like 21B
chr5_+_124579134 0.77 ENSMUST00000031333.3
Gtf2h3
general transcription factor IIH, polypeptide 3
chr10_+_127041931 0.77 ENSMUST00000006915.7
ENSMUST00000120542.1
Mettl1
methyltransferase like 1
chr2_+_112454997 0.77 ENSMUST00000069747.5
Emc7
ER membrane protein complex subunit 7
chr2_-_34826071 0.76 ENSMUST00000113077.1
ENSMUST00000028220.3
Fbxw2
F-box and WD-40 domain protein 2
chr5_+_115341225 0.75 ENSMUST00000031508.4
Triap1
TP53 regulated inhibitor of apoptosis 1
chr10_-_81545175 0.74 ENSMUST00000043604.5
Gna11
guanine nucleotide binding protein, alpha 11
chr2_+_144556306 0.74 ENSMUST00000155876.1
ENSMUST00000149697.1
Sec23b
SEC23B (S. cerevisiae)
chr13_-_58402449 0.73 ENSMUST00000177019.1
Hnrnpk
heterogeneous nuclear ribonucleoprotein K
chr2_+_76675265 0.73 ENSMUST00000111920.1
Plekha3
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 3
chr9_+_50768228 0.72 ENSMUST00000042391.6
Fdxacb1
ferredoxin-fold anticodon binding domain containing 1
chr4_+_126677630 0.72 ENSMUST00000030642.2
Psmb2
proteasome (prosome, macropain) subunit, beta type 2
chr4_-_147904643 0.72 ENSMUST00000150881.1
Mfn2
mitofusin 2
chr11_+_83302641 0.72 ENSMUST00000176430.1
ENSMUST00000065692.7
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr11_+_93996082 0.71 ENSMUST00000041956.7
Spag9
sperm associated antigen 9
chr7_+_16119868 0.71 ENSMUST00000006178.4
Kptn
kaptin
chr16_+_32247221 0.70 ENSMUST00000178573.1
ENSMUST00000023474.3
Wdr53
WD repeat domain 53
chr10_+_36974536 0.70 ENSMUST00000019911.7
Hdac2
histone deacetylase 2
chr16_-_18248697 0.70 ENSMUST00000115645.3
Ranbp1
RAN binding protein 1
chr8_+_34154563 0.70 ENSMUST00000033933.5
Tmem66
transmembrane protein 66
chr13_-_58215615 0.69 ENSMUST00000058735.5
ENSMUST00000076454.6
Ubqln1
ubiquilin 1
chr4_+_98923845 0.69 ENSMUST00000091358.4
Usp1
ubiquitin specific peptidase 1
chr17_+_46646225 0.69 ENSMUST00000002844.7
ENSMUST00000113429.1
ENSMUST00000113430.1
Mrpl2
mitochondrial ribosomal protein L2
chr5_-_24577467 0.68 ENSMUST00000030795.8
Abcf2
ATP-binding cassette, sub-family F (GCN20), member 2
chr9_-_50768109 0.67 ENSMUST00000177546.1
ENSMUST00000176238.1
1110032A03Rik
RIKEN cDNA 1110032A03 gene
chr19_+_3282901 0.67 ENSMUST00000025745.3
ENSMUST00000025743.6
Mrpl21
mitochondrial ribosomal protein L21
chr13_+_73604002 0.67 ENSMUST00000022102.7
Clptm1l
CLPTM1-like
chr1_-_59120079 0.67 ENSMUST00000094917.3
Tmem237
transmembrane protein 237
chr1_-_59119748 0.66 ENSMUST00000087475.4
Tmem237
transmembrane protein 237
chr7_+_138846579 0.66 ENSMUST00000155672.1
Ppp2r2d
protein phosphatase 2, regulatory subunit B, delta isoform
chr17_+_14978864 0.66 ENSMUST00000061688.9
9030025P20Rik
RIKEN cDNA 9030025P20 gene
chr10_+_58446845 0.65 ENSMUST00000003310.5
Ranbp2
RAN binding protein 2
chrX_+_57053549 0.65 ENSMUST00000114751.2
ENSMUST00000088652.5
Htatsf1
HIV TAT specific factor 1
chr3_+_138143888 0.63 ENSMUST00000161141.1
Trmt10a
tRNA methyltransferase 10A
chr11_+_60417238 0.63 ENSMUST00000070681.6
Gid4
GID complex subunit 4, VID24 homolog (S. cerevisiae)
chr2_-_103761178 0.63 ENSMUST00000028608.6
Nat10
N-acetyltransferase 10
chr9_-_44965519 0.62 ENSMUST00000125642.1
ENSMUST00000117506.1
ENSMUST00000117549.1
Ube4a
ubiquitination factor E4A, UFD2 homolog (S. cerevisiae)
chr11_-_98587193 0.62 ENSMUST00000052919.7
Ormdl3
ORM1-like 3 (S. cerevisiae)
chr3_+_103058302 0.61 ENSMUST00000029445.6
Nras
neuroblastoma ras oncogene
chr7_-_35056467 0.61 ENSMUST00000130491.1
Cebpg
CCAAT/enhancer binding protein (C/EBP), gamma
chr5_-_124579045 0.60 ENSMUST00000135361.1
ENSMUST00000031334.8
Eif2b1
eukaryotic translation initiation factor 2B, subunit 1 (alpha)
chr10_+_80141457 0.59 ENSMUST00000105367.1
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr7_+_132931142 0.59 ENSMUST00000106157.1
Zranb1
zinc finger, RAN-binding domain containing 1
chr4_+_98923810 0.58 ENSMUST00000030289.2
Usp1
ubiquitin specific peptidase 1
chr5_-_115341142 0.57 ENSMUST00000139167.1
Gatc
glutamyl-tRNA(Gln) amidotransferase, subunit C homolog (bacterial)
chr16_-_4077778 0.57 ENSMUST00000006137.8
Trap1
TNF receptor-associated protein 1
chr8_+_117157972 0.57 ENSMUST00000064488.4
ENSMUST00000162997.1
Gan
giant axonal neuropathy
chr16_+_14705832 0.56 ENSMUST00000023356.6
Snai2
snail homolog 2 (Drosophila)
chr11_+_70700473 0.56 ENSMUST00000152618.2
ENSMUST00000102554.1
ENSMUST00000094499.4
ENSMUST00000072187.5
Kif1c
kinesin family member 1C
chr11_+_96034885 0.55 ENSMUST00000006217.3
ENSMUST00000107700.3
Snf8
SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
chr11_-_76243687 0.55 ENSMUST00000017430.5
Glod4
glyoxalase domain containing 4
chr5_+_29735940 0.55 ENSMUST00000114839.1
Dnajb6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr13_-_58402476 0.54 ENSMUST00000175847.1
ENSMUST00000043269.7
ENSMUST00000177060.1
Hnrnpk
heterogeneous nuclear ribonucleoprotein K
chr2_+_152226839 0.54 ENSMUST00000099224.3
ENSMUST00000124791.1
ENSMUST00000133119.1
Csnk2a1
casein kinase 2, alpha 1 polypeptide
chr17_-_27820445 0.54 ENSMUST00000114859.1
D17Wsu92e
DNA segment, Chr 17, Wayne State University 92, expressed
chrX_-_36864238 0.54 ENSMUST00000115249.3
ENSMUST00000115248.3
C330007P06Rik
RIKEN cDNA C330007P06 gene
chr19_-_6057736 0.54 ENSMUST00000007482.6
Mrpl49
mitochondrial ribosomal protein L49
chr6_+_114643094 0.53 ENSMUST00000032457.10
Atg7
autophagy related 7
chr8_+_27023793 0.53 ENSMUST00000033873.7
Erlin2
ER lipid raft associated 2
chr3_+_36552600 0.52 ENSMUST00000029269.5
ENSMUST00000136890.1
Exosc9
exosome component 9
chr4_+_107879745 0.52 ENSMUST00000030348.5
Magoh
mago-nashi homolog, proliferation-associated (Drosophila)
chr12_+_52097737 0.52 ENSMUST00000040090.9
Nubpl
nucleotide binding protein-like
chr18_-_68300194 0.51 ENSMUST00000152193.1
Fam210a
family with sequence similarity 210, member A

Network of associatons between targets according to the STRING database.

First level regulatory network of Creb1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.7 2.2 GO:0035973 aggrephagy(GO:0035973)
0.7 2.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.6 1.9 GO:1903722 regulation of centriole elongation(GO:1903722)
0.6 1.8 GO:1901950 dense core granule localization(GO:0032253) dense core granule transport(GO:1901950) regulation of dense core granule transport(GO:1904809) positive regulation of dense core granule transport(GO:1904811)
0.6 1.7 GO:0061144 alveolar secondary septum development(GO:0061144)
0.5 5.1 GO:0070236 phospholipid homeostasis(GO:0055091) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.5 1.5 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.5 2.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.5 1.9 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.5 5.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.5 2.3 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.5 1.4 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.4 1.3 GO:0090157 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157)
0.4 1.3 GO:0021759 globus pallidus development(GO:0021759)
0.4 1.7 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.4 1.3 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.4 1.1 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.3 1.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.3 1.3 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.3 2.9 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.3 0.3 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.3 1.6 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.3 1.2 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.3 0.9 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.3 1.2 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.3 1.9 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.3 1.1 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.2 1.5 GO:0060701 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.2 1.7 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.2 1.0 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.2 0.7 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.2 1.9 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.2 1.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2 4.0 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2 2.5 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.2 0.6 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.2 2.8 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.2 3.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.2 0.6 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.2 0.6 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.2 0.6 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.2 2.6 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 3.7 GO:0015693 magnesium ion transport(GO:0015693)
0.2 0.7 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 1.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.2 0.3 GO:0006272 leading strand elongation(GO:0006272)
0.2 0.5 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.2 0.7 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.2 0.8 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.2 1.8 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.2 0.5 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 1.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.2 1.5 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.2 0.9 GO:0051189 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.2 1.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 1.3 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.4 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 0.8 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 1.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.8 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.8 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.5 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.4 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.1 0.5 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 0.7 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 1.4 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 0.7 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) regulation of zinc ion transport(GO:0071579)
0.1 3.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 1.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.3 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.1 1.4 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 1.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.4 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 2.0 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 1.0 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.7 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.5 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.6 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.1 1.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.8 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.1 0.9 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.1 3.8 GO:0043039 tRNA aminoacylation(GO:0043039)
0.1 0.4 GO:0051661 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.1 0.3 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.4 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.1 0.5 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.9 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.6 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.3 GO:0051309 female meiosis chromosome separation(GO:0051309)
0.1 0.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.7 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 2.6 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.4 GO:1903182 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.1 1.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.3 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.1 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.4 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 1.2 GO:0061462 protein localization to lysosome(GO:0061462)
0.1 0.4 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 2.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.8 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.8 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.4 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.4 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0 1.0 GO:0016556 mRNA modification(GO:0016556)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.4 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 1.2 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.5 GO:0042026 protein refolding(GO:0042026)
0.0 0.1 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 1.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.5 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:0035188 blastocyst hatching(GO:0001835) DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 1.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 4.7 GO:0006839 mitochondrial transport(GO:0006839)
0.0 2.7 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.4 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.0 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.4 GO:0051452 intracellular pH reduction(GO:0051452)
0.0 0.3 GO:0008209 androgen metabolic process(GO:0008209)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.3 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.9 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.0 GO:0048320 axial mesoderm formation(GO:0048320)
0.0 0.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.6 3.6 GO:1990393 3M complex(GO:1990393)
0.5 1.5 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.5 2.0 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.5 2.7 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.5 3.2 GO:0097452 GAIT complex(GO:0097452)
0.3 1.7 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.3 2.0 GO:0005663 DNA replication factor C complex(GO:0005663)
0.3 2.4 GO:0000439 core TFIIH complex(GO:0000439)
0.2 0.7 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.2 2.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 3.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 0.6 GO:0000814 ESCRT II complex(GO:0000814)
0.2 2.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 1.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 0.6 GO:0035339 SPOTS complex(GO:0035339)
0.1 7.8 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.9 GO:0090543 Flemming body(GO:0090543)
0.1 1.9 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 0.6 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 1.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.5 GO:0032444 activin responsive factor complex(GO:0032444) SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.8 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.5 GO:0043202 lysosomal lumen(GO:0043202)
0.1 1.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.4 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 1.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.4 GO:0030689 Noc complex(GO:0030689)
0.1 0.4 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.6 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 2.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 1.0 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 2.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.4 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.1 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 3.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.3 GO:0000242 pericentriolar material(GO:0000242)
0.1 1.7 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1 1.9 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.4 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.4 GO:0033263 CORVET complex(GO:0033263)
0.1 9.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 0.9 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.8 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.2 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.8 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.7 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.7 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.8 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 1.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.7 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.7 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.5 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.3 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.9 GO:0031201 SNARE complex(GO:0031201)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 1.7 GO:0005902 microvillus(GO:0005902)
0.0 2.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.5 GO:0043596 nuclear replication fork(GO:0043596)
0.0 5.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 3.1 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.5 4.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.5 1.5 GO:0019776 Atg8 ligase activity(GO:0019776)
0.4 1.3 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.4 1.6 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.4 1.2 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.4 2.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.4 2.1 GO:0097001 ceramide binding(GO:0097001)
0.3 1.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.3 2.5 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.3 1.2 GO:0035851 histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851)
0.3 0.9 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3 0.8 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 1.5 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.2 0.7 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 2.0 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.2 1.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 1.9 GO:0032564 dATP binding(GO:0032564)
0.2 0.6 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.2 3.0 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 2.0 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 5.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 1.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 3.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.2 1.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.4 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 0.7 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.8 GO:0004043 L-aminoadipate-semialdehyde dehydrogenase activity(GO:0004043)
0.1 2.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 3.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 1.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 0.5 GO:0004802 transketolase activity(GO:0004802)
0.1 0.3 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.5 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 2.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.4 GO:0016433 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (adenine) methyltransferase activity(GO:0016433)
0.1 2.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 5.5 GO:0008374 O-acyltransferase activity(GO:0008374)
0.1 0.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 1.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.3 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 0.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 3.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 1.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.3 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.8 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.8 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 2.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.4 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 0.4 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.8 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 5.7 GO:0051082 unfolded protein binding(GO:0051082)
0.1 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 2.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 1.1 GO:0051400 BH domain binding(GO:0051400)
0.1 0.5 GO:0000182 rDNA binding(GO:0000182)
0.1 0.9 GO:0070402 NADPH binding(GO:0070402)
0.0 1.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 1.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.0 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.7 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 1.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 3.0 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.9 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.8 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.7 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.2 GO:0000049 tRNA binding(GO:0000049)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.8 GO:0030276 clathrin binding(GO:0030276)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 3.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.4 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 0.6 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 1.3 GO:0004497 monooxygenase activity(GO:0004497)
0.0 1.1 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.3 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 7.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 2.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 3.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 2.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 4.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.9 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.5 PID GLYPICAN 1PATHWAY Glypican 1 network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 2.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 2.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 1.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 3.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 3.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 7.4 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.1 2.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 0.3 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.1 1.5 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.1 0.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.6 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.9 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 2.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.8 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 2.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 4.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 1.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production