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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Ebf3

Z-value: 2.67

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Transcription factors associated with Ebf3

Gene Symbol Gene ID Gene Info
Ebf3
ENSMUSG00000010476.7 early B cell factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ebf3mm10_v2_chr7_-_137314394_1373144450.271.1e-01Click!

Activity profile of Ebf3 motif

Sorted Z-values of Ebf3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_7967817 22.67 ENSMUST00000033502.7
Gata1
GATA binding protein 1
chr2_-_28621932 22.33 ENSMUST00000028156.7
ENSMUST00000164290.1
Gfi1b
growth factor independent 1B
chr11_-_102365111 21.96 ENSMUST00000006749.9
Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr12_+_109453455 19.91 ENSMUST00000109844.4
ENSMUST00000109842.2
ENSMUST00000109843.1
ENSMUST00000109846.4
ENSMUST00000173539.1
ENSMUST00000109841.2
Dlk1
delta-like 1 homolog (Drosophila)
chr17_-_48451510 14.63 ENSMUST00000024794.5
Tspo2
translocator protein 2
chr11_-_53480178 13.12 ENSMUST00000104955.2
Sowaha
sosondowah ankyrin repeat domain family member A
chr2_-_28084877 12.05 ENSMUST00000028179.8
ENSMUST00000117486.1
ENSMUST00000135472.1
Fcnb
ficolin B
chr11_+_95010277 12.04 ENSMUST00000124735.1
Samd14
sterile alpha motif domain containing 14
chr14_-_60086832 11.88 ENSMUST00000080368.5
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr15_+_80623499 11.22 ENSMUST00000043149.7
Grap2
GRB2-related adaptor protein 2
chr14_-_69503316 10.94 ENSMUST00000179116.2
Gm21464
predicted gene, 21464
chr10_-_128401218 10.14 ENSMUST00000042666.5
Slc39a5
solute carrier family 39 (metal ion transporter), member 5
chr11_-_116076986 9.68 ENSMUST00000153408.1
Unc13d
unc-13 homolog D (C. elegans)
chr19_-_45816007 9.36 ENSMUST00000079431.3
ENSMUST00000026247.6
ENSMUST00000162528.2
Kcnip2
Kv channel-interacting protein 2
chr11_+_115877497 9.32 ENSMUST00000144032.1
Myo15b
myosin XVB
chr9_-_44288131 9.28 ENSMUST00000160384.1
Abcg4
ATP-binding cassette, sub-family G (WHITE), member 4
chr11_+_115900125 9.19 ENSMUST00000142089.1
ENSMUST00000131566.1
Smim5
small integral membrane protein 5
chr7_+_142442330 8.83 ENSMUST00000149529.1
Tnni2
troponin I, skeletal, fast 2
chr17_+_48359891 8.69 ENSMUST00000024792.6
Treml1
triggering receptor expressed on myeloid cells-like 1
chr1_+_75400070 8.33 ENSMUST00000113589.1
Speg
SPEG complex locus
chr14_-_60087347 7.96 ENSMUST00000149414.1
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr1_-_193370260 7.78 ENSMUST00000016323.4
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr4_+_120666562 7.72 ENSMUST00000094814.4
Cited4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chrX_+_7822289 7.51 ENSMUST00000009875.4
Kcnd1
potassium voltage-gated channel, Shal-related family, member 1
chr11_+_87755567 7.48 ENSMUST00000123700.1
A430104N18Rik
RIKEN cDNA A430104N18 gene
chr6_-_86669136 7.07 ENSMUST00000001184.7
Mxd1
MAX dimerization protein 1
chr7_-_126414855 7.01 ENSMUST00000032968.5
Cd19
CD19 antigen
chr7_+_24897381 6.99 ENSMUST00000003469.7
Cd79a
CD79A antigen (immunoglobulin-associated alpha)
chr7_+_142441808 6.75 ENSMUST00000105971.1
ENSMUST00000145287.1
Tnni2
troponin I, skeletal, fast 2
chr7_+_19411086 6.60 ENSMUST00000003643.1
Ckm
creatine kinase, muscle
chr16_-_76022266 6.48 ENSMUST00000114240.1
Samsn1
SAM domain, SH3 domain and nuclear localization signals, 1
chr1_-_193370225 6.44 ENSMUST00000169907.1
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr10_-_60219260 6.22 ENSMUST00000135158.2
Chst3
carbohydrate (chondroitin 6/keratan) sulfotransferase 3
chr7_+_28982832 6.21 ENSMUST00000085835.6
Map4k1
mitogen-activated protein kinase kinase kinase kinase 1
chr11_+_77009265 6.19 ENSMUST00000129572.2
Slc6a4
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
chr12_-_109068173 6.18 ENSMUST00000073156.7
Begain
brain-enriched guanylate kinase-associated
chr2_+_25372315 5.89 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2
suppressor APC domain containing 2
chr1_+_74278550 5.77 ENSMUST00000077985.3
Gpbar1
G protein-coupled bile acid receptor 1
chrX_+_48146436 5.73 ENSMUST00000033427.6
Sash3
SAM and SH3 domain containing 3
chr15_-_66812593 5.73 ENSMUST00000100572.3
Sla
src-like adaptor
chr9_+_45403138 5.66 ENSMUST00000041005.5
Fxyd2
FXYD domain-containing ion transport regulator 2
chr11_-_98053415 5.64 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr7_-_25615874 5.42 ENSMUST00000098663.1
Gm7092
predicted gene 7092
chr11_-_11808923 5.32 ENSMUST00000109664.1
ENSMUST00000150714.1
ENSMUST00000047689.4
ENSMUST00000171938.1
ENSMUST00000171080.1
Fignl1
fidgetin-like 1
chr3_-_100489324 5.27 ENSMUST00000061455.8
Fam46c
family with sequence similarity 46, member C
chr2_-_126499839 5.19 ENSMUST00000040128.5
Atp8b4
ATPase, class I, type 8B, member 4
chr6_+_30639218 5.18 ENSMUST00000031806.9
Cpa1
carboxypeptidase A1, pancreatic
chr2_-_118703963 5.18 ENSMUST00000104937.1
Ankrd63
ankyrin repeat domain 63
chr4_+_133240778 5.12 ENSMUST00000030677.6
Map3k6
mitogen-activated protein kinase kinase kinase 6
chr7_-_142699510 5.05 ENSMUST00000105934.1
Ins2
insulin II
chr11_-_94474088 4.95 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
Cacna1g
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr5_+_30711564 4.94 ENSMUST00000114729.1
Dpysl5
dihydropyrimidinase-like 5
chr2_-_13491900 4.68 ENSMUST00000091436.5
Cubn
cubilin (intrinsic factor-cobalamin receptor)
chr1_-_136234113 4.67 ENSMUST00000120339.1
ENSMUST00000048668.8
5730559C18Rik
RIKEN cDNA 5730559C18 gene
chr10_-_88146867 4.65 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
Parpbp
PARP1 binding protein
chr7_-_25297866 4.64 ENSMUST00000148150.1
ENSMUST00000155118.1
Pafah1b3
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr19_+_58728887 4.63 ENSMUST00000048644.5
Pnliprp1
pancreatic lipase related protein 1
chr15_+_78244781 4.57 ENSMUST00000096357.5
ENSMUST00000133618.1
Ncf4
neutrophil cytosolic factor 4
chr12_-_114416895 4.52 ENSMUST00000179796.1
Ighv6-5
immunoglobulin heavy variable V6-5
chr5_+_136967859 4.46 ENSMUST00000001790.5
Cldn15
claudin 15
chrX_-_162964557 4.45 ENSMUST00000038769.2
S100g
S100 calcium binding protein G
chr7_+_128062657 4.44 ENSMUST00000120355.1
ENSMUST00000106240.2
ENSMUST00000098015.3
Itgam
integrin alpha M
chr9_+_95637601 4.44 ENSMUST00000015498.8
Pcolce2
procollagen C-endopeptidase enhancer 2
chr11_-_102946688 4.43 ENSMUST00000057849.5
C1ql1
complement component 1, q subcomponent-like 1
chr4_+_43957401 4.34 ENSMUST00000030202.7
Glipr2
GLI pathogenesis-related 2
chr13_-_22009730 4.33 ENSMUST00000006341.2
Prss16
protease, serine, 16 (thymus)
chr13_+_55399648 4.32 ENSMUST00000057167.7
Slc34a1
solute carrier family 34 (sodium phosphate), member 1
chr8_-_105851981 4.30 ENSMUST00000040776.4
Cenpt
centromere protein T
chr5_+_37245792 4.29 ENSMUST00000031004.7
Crmp1
collapsin response mediator protein 1
chrX_-_150813637 4.20 ENSMUST00000112700.1
Maged2
melanoma antigen, family D, 2
chr13_+_108214389 4.15 ENSMUST00000022207.8
Elovl7
ELOVL family member 7, elongation of long chain fatty acids (yeast)
chr7_+_128062635 4.08 ENSMUST00000064821.7
ENSMUST00000106242.3
Itgam
integrin alpha M
chr1_-_171281181 4.08 ENSMUST00000073120.4
Ppox
protoporphyrinogen oxidase
chr15_+_78913916 4.01 ENSMUST00000089378.4
Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr2_+_154548888 4.00 ENSMUST00000045116.4
ENSMUST00000109709.3
1700003F12Rik
RIKEN cDNA 1700003F12 gene
chr11_+_96929367 3.92 ENSMUST00000062172.5
Prr15l
proline rich 15-like
chr4_-_148130678 3.87 ENSMUST00000030862.4
Draxin
dorsal inhibitory axon guidance protein
chr11_-_72411695 3.87 ENSMUST00000108500.1
ENSMUST00000050226.6
Smtnl2
smoothelin-like 2
chr8_+_70493156 3.87 ENSMUST00000008032.7
Crlf1
cytokine receptor-like factor 1
chr14_-_62292959 3.84 ENSMUST00000063169.8
Dleu7
deleted in lymphocytic leukemia, 7
chrX_+_75382384 3.83 ENSMUST00000033541.4
Fundc2
FUN14 domain containing 2
chr4_-_149676043 3.83 ENSMUST00000118704.1
Pik3cd
phosphatidylinositol 3-kinase catalytic delta polypeptide
chr7_+_80186835 3.68 ENSMUST00000107383.1
ENSMUST00000032754.7
Sema4b
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr16_+_32608973 3.68 ENSMUST00000120680.1
Tfrc
transferrin receptor
chr5_+_30711849 3.62 ENSMUST00000088081.4
ENSMUST00000101442.3
Dpysl5
dihydropyrimidinase-like 5
chr4_+_43957678 3.62 ENSMUST00000107855.1
Glipr2
GLI pathogenesis-related 2
chr4_+_138725282 3.52 ENSMUST00000030530.4
ENSMUST00000124660.1
Pla2g2c
phospholipase A2, group IIC
chr11_-_59035064 3.40 ENSMUST00000138587.1
Obscn
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr14_+_54476100 3.39 ENSMUST00000164766.1
ENSMUST00000164697.1
Rem2
rad and gem related GTP binding protein 2
chr16_+_32608920 3.37 ENSMUST00000023486.8
Tfrc
transferrin receptor
chr11_+_63128973 3.35 ENSMUST00000108702.1
Pmp22
peripheral myelin protein 22
chr6_+_120093348 3.34 ENSMUST00000112711.2
Ninj2
ninjurin 2
chr7_-_4546567 3.33 ENSMUST00000065957.5
Syt5
synaptotagmin V
chr7_+_128062698 3.32 ENSMUST00000119696.1
Itgam
integrin alpha M
chr17_-_6782775 3.28 ENSMUST00000064234.6
Ezr
ezrin
chr7_-_3677509 3.21 ENSMUST00000038743.8
Tmc4
transmembrane channel-like gene family 4
chr8_+_84970068 3.17 ENSMUST00000164807.1
Prdx2
peroxiredoxin 2
chr15_+_99224976 3.08 ENSMUST00000041415.3
Kcnh3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr4_-_93335510 3.07 ENSMUST00000066774.4
Tusc1
tumor suppressor candidate 1
chr17_+_47672720 3.06 ENSMUST00000152724.1
Usp49
ubiquitin specific peptidase 49
chr4_-_129121699 3.01 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
Hpca
hippocalcin
chr11_+_16951371 2.98 ENSMUST00000109635.1
ENSMUST00000061327.1
Fbxo48
F-box protein 48
chr5_+_137629169 2.96 ENSMUST00000176667.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr11_+_96929260 2.95 ENSMUST00000054311.5
ENSMUST00000107636.3
Prr15l
proline rich 15-like
chr2_+_130295148 2.91 ENSMUST00000110288.2
Ebf4
early B cell factor 4
chr8_+_119700009 2.90 ENSMUST00000095171.3
Atp2c2
ATPase, Ca++ transporting, type 2C, member 2
chr1_+_135840857 2.89 ENSMUST00000179863.1
ENSMUST00000112086.2
ENSMUST00000112087.2
ENSMUST00000112085.2
ENSMUST00000178854.1
ENSMUST00000027671.5
Tnnt2
troponin T2, cardiac
chr11_+_101316200 2.84 ENSMUST00000142640.1
ENSMUST00000019470.7
Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr18_+_34624621 2.82 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr11_+_3989924 2.81 ENSMUST00000109981.1
Gal3st1
galactose-3-O-sulfotransferase 1
chr7_-_45920830 2.78 ENSMUST00000164119.1
Emp3
epithelial membrane protein 3
chr11_+_101316917 2.74 ENSMUST00000151385.1
Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr10_+_116143881 2.70 ENSMUST00000105271.2
Ptprr
protein tyrosine phosphatase, receptor type, R
chr9_-_32542861 2.70 ENSMUST00000183767.1
Fli1
Friend leukemia integration 1
chr10_+_60346851 2.67 ENSMUST00000020301.7
ENSMUST00000105460.1
ENSMUST00000170507.1
4632428N05Rik
RIKEN cDNA 4632428N05 gene
chr15_+_79516396 2.67 ENSMUST00000010974.7
Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr4_+_141147911 2.66 ENSMUST00000030757.9
Fbxo42
F-box protein 42
chr2_-_113829069 2.64 ENSMUST00000024005.7
Scg5
secretogranin V
chr9_-_37433138 2.64 ENSMUST00000115038.1
Robo3
roundabout homolog 3 (Drosophila)
chr17_+_47726834 2.63 ENSMUST00000024782.5
ENSMUST00000144955.1
Pgc
progastricsin (pepsinogen C)
chr9_+_103305156 2.61 ENSMUST00000035164.3
Topbp1
topoisomerase (DNA) II binding protein 1
chr9_-_30922452 2.61 ENSMUST00000065112.6
Adamts15
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15
chr2_+_26319741 2.61 ENSMUST00000066889.6
Gpsm1
G-protein signalling modulator 1 (AGS3-like, C. elegans)
chr11_-_96977660 2.57 ENSMUST00000107626.1
ENSMUST00000107624.1
Sp2
Sp2 transcription factor
chr17_-_50094277 2.56 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr2_+_30441831 2.54 ENSMUST00000131476.1
Ppp2r4
protein phosphatase 2A, regulatory subunit B (PR 53)
chr9_+_30942541 2.50 ENSMUST00000068135.6
Adamts8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
chr6_-_69284319 2.48 ENSMUST00000103349.1
Igkv4-69
immunoglobulin kappa variable 4-69
chr19_+_45149833 2.41 ENSMUST00000026236.9
Tlx1
T cell leukemia, homeobox 1
chr6_-_73221625 2.39 ENSMUST00000064948.6
ENSMUST00000114040.1
Dnah6
dynein, axonemal, heavy chain 6
chr14_-_34588654 2.38 ENSMUST00000022328.6
ENSMUST00000064098.6
ENSMUST00000022327.5
ENSMUST00000022330.7
Ldb3
LIM domain binding 3
chr4_-_141416002 2.37 ENSMUST00000006378.2
ENSMUST00000105788.1
Clcnkb
chloride channel Kb
chr2_-_153241402 2.35 ENSMUST00000056924.7
Plagl2
pleiomorphic adenoma gene-like 2
chr4_-_131821516 2.31 ENSMUST00000097860.2
Ptpru
protein tyrosine phosphatase, receptor type, U
chr17_+_23679363 2.30 ENSMUST00000024699.2
Cldn6
claudin 6
chr2_+_125068118 2.27 ENSMUST00000070353.3
Slc24a5
solute carrier family 24, member 5
chr11_+_75650501 2.24 ENSMUST00000102505.3
Myo1c
myosin IC
chr7_-_25297967 2.23 ENSMUST00000005583.5
Pafah1b3
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr5_-_147400352 2.17 ENSMUST00000049324.8
ENSMUST00000176456.1
ENSMUST00000110549.1
Flt3
FMS-like tyrosine kinase 3
chr14_+_62292475 2.15 ENSMUST00000166879.1
Rnaseh2b
ribonuclease H2, subunit B
chr6_-_91116785 2.13 ENSMUST00000113509.1
ENSMUST00000032179.7
Nup210
nucleoporin 210
chr4_-_129121234 2.11 ENSMUST00000030572.3
Hpca
hippocalcin
chr14_+_67745229 2.09 ENSMUST00000111095.2
Gnrh1
gonadotropin releasing hormone 1
chr11_-_3539228 2.08 ENSMUST00000075118.3
ENSMUST00000136243.1
ENSMUST00000170588.1
ENSMUST00000020721.8
Smtn
smoothelin
chr7_+_126781483 2.06 ENSMUST00000172352.1
ENSMUST00000094037.4
Tbx6
T-box 6
chr4_+_130915949 2.06 ENSMUST00000030316.6
Laptm5
lysosomal-associated protein transmembrane 5
chr4_+_154960915 2.03 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr2_+_152754156 2.03 ENSMUST00000010020.5
Cox4i2
cytochrome c oxidase subunit IV isoform 2
chr7_-_28372233 1.97 ENSMUST00000094644.4
Plekhg2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr17_-_80207299 1.93 ENSMUST00000063417.9
Srsf7
serine/arginine-rich splicing factor 7
chr3_+_102735202 1.93 ENSMUST00000119902.1
Tspan2
tetraspanin 2
chr14_+_62332068 1.91 ENSMUST00000022499.6
Rnaseh2b
ribonuclease H2, subunit B
chr7_+_49975228 1.88 ENSMUST00000107603.1
Nell1
NEL-like 1
chr7_-_100932140 1.88 ENSMUST00000107032.1
Arhgef17
Rho guanine nucleotide exchange factor (GEF) 17
chr3_+_108739658 1.88 ENSMUST00000133931.2
Aknad1
AKNA domain containing 1
chr6_-_32588192 1.87 ENSMUST00000115096.2
Plxna4
plexin A4
chr13_-_49309217 1.87 ENSMUST00000110087.2
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr11_-_69837781 1.86 ENSMUST00000108634.2
Nlgn2
neuroligin 2
chr12_-_76962178 1.82 ENSMUST00000110395.3
ENSMUST00000082136.5
Max
Max protein
chrX_+_144688907 1.78 ENSMUST00000112843.1
Zcchc16
zinc finger, CCHC domain containing 16
chr1_-_13127163 1.77 ENSMUST00000047577.6
Prdm14
PR domain containing 14
chr5_-_123879992 1.73 ENSMUST00000164267.1
Gpr81
G protein-coupled receptor 81
chr7_-_119479249 1.72 ENSMUST00000033263.4
Umod
uromodulin
chr14_-_54966570 1.72 ENSMUST00000124930.1
ENSMUST00000134256.1
ENSMUST00000081857.6
ENSMUST00000145322.1
Myh6
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr5_+_129725063 1.72 ENSMUST00000086046.3
Gbas
glioblastoma amplified sequence
chr5_-_139130159 1.70 ENSMUST00000129851.1
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr7_-_45824750 1.65 ENSMUST00000071937.5
Kcnj14
potassium inwardly-rectifying channel, subfamily J, member 14
chr2_+_178414512 1.64 ENSMUST00000094251.4
Fam217b
family with sequence similarity 217, member B
chr9_-_67043709 1.63 ENSMUST00000113689.1
ENSMUST00000113684.1
Tpm1
tropomyosin 1, alpha
chr6_-_116673790 1.62 ENSMUST00000035842.4
Rassf4
Ras association (RalGDS/AF-6) domain family member 4
chr5_-_139129662 1.60 ENSMUST00000026973.7
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr4_+_137681663 1.57 ENSMUST00000047243.5
Rap1gap
Rap1 GTPase-activating protein
chr17_+_35866056 1.56 ENSMUST00000122899.1
Ppp1r18
protein phosphatase 1, regulatory subunit 18
chr7_+_4690760 1.54 ENSMUST00000048248.7
Brsk1
BR serine/threonine kinase 1
chr17_+_83706137 1.54 ENSMUST00000112350.1
ENSMUST00000112349.2
ENSMUST00000112352.3
Mta3
metastasis associated 3
chr9_+_121760000 1.52 ENSMUST00000093772.3
Zfp651
zinc finger protein 651
chr3_+_59006978 1.51 ENSMUST00000040325.7
ENSMUST00000164225.1
ENSMUST00000040846.8
ENSMUST00000029393.8
Med12l
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)-like
chr15_+_76797628 1.51 ENSMUST00000165535.2
Gm17271
predicted gene, 17271
chr11_-_29825649 1.51 ENSMUST00000104962.1
4931440F15Rik
RIKEN cDNA 4931440F15 gene
chr3_+_100489508 1.50 ENSMUST00000122898.1
Gm12474
predicted gene 12474
chr11_+_70432627 1.50 ENSMUST00000084954.6
ENSMUST00000108568.3
ENSMUST00000079056.2
ENSMUST00000102564.4
ENSMUST00000124943.1
ENSMUST00000150076.1
ENSMUST00000102563.1
Arrb2
arrestin, beta 2
chr8_+_71469186 1.47 ENSMUST00000124745.1
ENSMUST00000138892.1
ENSMUST00000147642.1
Dda1
DET1 and DDB1 associated 1
chr10_-_127060163 1.46 ENSMUST00000040307.5
March9
membrane-associated ring finger (C3HC4) 9
chr6_-_69631933 1.43 ENSMUST00000177697.1
Igkv4-54
immunoglobulin kappa chain variable 4-54
chr7_-_45092198 1.41 ENSMUST00000140449.1
ENSMUST00000117546.1
ENSMUST00000019683.3
Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr1_+_172312367 1.40 ENSMUST00000039506.9
Igsf8
immunoglobulin superfamily, member 8
chr8_-_71701796 1.40 ENSMUST00000034260.7
B3gnt3
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
chr8_-_111082043 1.39 ENSMUST00000039597.7
Clec18a
C-type lectin domain family 18, member A
chr1_+_40805578 1.39 ENSMUST00000114765.2
Tmem182
transmembrane protein 182
chr4_+_117835387 1.39 ENSMUST00000169885.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr17_+_83706170 1.38 ENSMUST00000067826.8
Mta3
metastasis associated 3
chr5_+_137629112 1.38 ENSMUST00000031734.9
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr5_+_103425181 1.37 ENSMUST00000048957.9
Ptpn13
protein tyrosine phosphatase, non-receptor type 13
chr4_-_138725262 1.37 ENSMUST00000105811.2
Ubxn10
UBX domain protein 10
chr7_-_127208423 1.36 ENSMUST00000120705.1
Tbc1d10b
TBC1 domain family, member 10b
chr1_+_89454769 1.34 ENSMUST00000027521.8
ENSMUST00000074945.5
Agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr4_-_116627478 1.34 ENSMUST00000081182.4
ENSMUST00000030457.5
Nasp
nuclear autoantigenic sperm protein (histone-binding)
chr7_-_142372210 1.34 ENSMUST00000084412.5
Ifitm10
interferon induced transmembrane protein 10
chrX_-_38252398 1.33 ENSMUST00000089056.3
ENSMUST00000089054.4
ENSMUST00000066498.7
Tmem255a
transmembrane protein 255A
chr17_+_84626458 1.32 ENSMUST00000025101.8
Dync2li1
dynein cytoplasmic 2 light intermediate chain 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Ebf3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 22.7 GO:0030221 basophil differentiation(GO:0030221)
3.4 10.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
3.0 12.0 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
2.8 22.3 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
2.5 19.8 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
2.3 13.8 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
1.9 9.4 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
1.7 5.1 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
1.7 5.1 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) neuron projection maintenance(GO:1990535)
1.5 6.2 GO:0021941 negative regulation of cerebellar granule cell precursor proliferation(GO:0021941)
1.4 4.3 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
1.2 5.0 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
1.1 2.3 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
1.1 4.4 GO:0061743 motor learning(GO:0061743)
1.1 3.3 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
1.1 9.7 GO:0002432 granuloma formation(GO:0002432)
1.1 4.3 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
1.0 4.0 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
1.0 2.9 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.8 3.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.8 4.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.8 22.0 GO:0015701 bicarbonate transport(GO:0015701)
0.8 4.7 GO:0015889 cobalamin transport(GO:0015889)
0.8 23.4 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.8 4.5 GO:0061643 chemorepulsion of axon(GO:0061643)
0.6 1.3 GO:2000978 negative regulation of forebrain neuron differentiation(GO:2000978)
0.6 6.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.6 3.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.6 2.3 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.6 0.6 GO:0061198 fungiform papilla formation(GO:0061198)
0.6 3.9 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.5 3.8 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.5 1.6 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.5 2.2 GO:0002572 pro-T cell differentiation(GO:0002572)
0.5 2.6 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.5 4.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.5 3.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.5 2.9 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.5 4.7 GO:0070431 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.5 1.4 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.5 2.8 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.4 2.7 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.4 1.8 GO:0001827 inner cell mass cell fate commitment(GO:0001827) positive regulation of sperm motility(GO:1902093)
0.4 1.6 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.4 7.0 GO:0006968 cellular defense response(GO:0006968)
0.4 2.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.4 3.4 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.4 2.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.4 1.9 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.4 1.1 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.4 1.1 GO:0072244 metanephric glomerular epithelium development(GO:0072244)
0.3 1.4 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.3 1.7 GO:0072236 metanephric loop of Henle development(GO:0072236)
0.3 6.1 GO:0032060 bleb assembly(GO:0032060)
0.3 5.8 GO:2000810 regulation of bicellular tight junction assembly(GO:2000810)
0.3 3.2 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
0.3 0.6 GO:2000412 positive regulation of thymocyte migration(GO:2000412)
0.3 2.8 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 4.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.3 4.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.3 5.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.3 0.6 GO:0097117 guanylate kinase-associated protein clustering(GO:0097117)
0.3 5.6 GO:0045730 respiratory burst(GO:0045730)
0.3 4.3 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3 1.4 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.3 2.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.2 1.5 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.2 1.2 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.2 2.9 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 2.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 1.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.2 10.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 2.4 GO:0034377 plasma lipoprotein particle assembly(GO:0034377)
0.2 1.9 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.2 1.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 15.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 0.7 GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.2 10.2 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.2 9.3 GO:0033344 cholesterol efflux(GO:0033344)
0.2 0.9 GO:0072318 clathrin coat disassembly(GO:0072318)
0.2 0.8 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 2.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 8.0 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 0.7 GO:0030049 muscle filament sliding(GO:0030049)
0.1 5.7 GO:0032743 positive regulation of interleukin-2 production(GO:0032743)
0.1 0.3 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.1 0.8 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 2.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 3.5 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 1.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.1 2.7 GO:0035855 megakaryocyte development(GO:0035855)
0.1 1.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 3.9 GO:0030517 negative regulation of axon extension(GO:0030517)
0.1 0.5 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 3.1 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.1 14.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 5.3 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 3.1 GO:0045214 sarcomere organization(GO:0045214)
0.1 6.6 GO:0042398 cellular modified amino acid biosynthetic process(GO:0042398)
0.1 3.0 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.8 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 2.6 GO:0016486 peptide hormone processing(GO:0016486)
0.1 3.2 GO:0050919 negative chemotaxis(GO:0050919)
0.1 2.4 GO:0048535 lymph node development(GO:0048535)
0.1 0.8 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 3.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.7 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 1.1 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 1.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.1 3.0 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 1.0 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 0.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.4 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 8.3 GO:0055013 cardiac muscle cell development(GO:0055013)
0.1 1.7 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.1 1.0 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.2 GO:0016095 polyprenol catabolic process(GO:0016095)
0.1 5.2 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.1 2.8 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.1 1.9 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.2 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.1 0.2 GO:0010446 response to alkaline pH(GO:0010446)
0.1 1.3 GO:0043486 histone exchange(GO:0043486)
0.1 4.2 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 4.4 GO:0043627 response to estrogen(GO:0043627)
0.0 2.4 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 3.8 GO:0061726 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 1.0 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 5.2 GO:0007030 Golgi organization(GO:0007030)
0.0 0.1 GO:0033577 protein glycosylation in endoplasmic reticulum(GO:0033577)
0.0 1.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.0 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.7 GO:0042711 maternal behavior(GO:0042711)
0.0 0.1 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.0 4.9 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.1 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 6.2 GO:0007411 axon guidance(GO:0007411)
0.0 0.4 GO:0072422 signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422)
0.0 0.8 GO:0097006 regulation of plasma lipoprotein particle levels(GO:0097006)
0.0 0.7 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 3.3 GO:0051028 mRNA transport(GO:0051028)
0.0 0.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.6 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.9 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.5 GO:0003341 cilium movement(GO:0003341)
0.0 1.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.6 GO:0007340 acrosome reaction(GO:0007340)
0.0 2.0 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.3 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.5 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.4 GO:0051932 synaptic transmission, GABAergic(GO:0051932)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.6 GO:0008537 proteasome activator complex(GO:0008537)
1.0 18.5 GO:0005861 troponin complex(GO:0005861)
1.0 7.0 GO:0019815 B cell receptor complex(GO:0019815)
1.0 3.9 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.9 4.7 GO:0043202 lysosomal lumen(GO:0043202)
0.9 4.4 GO:0044301 climbing fiber(GO:0044301)
0.9 9.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.8 3.3 GO:0044393 microspike(GO:0044393) Schwann cell microvillus(GO:0097454)
0.7 4.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.7 3.3 GO:1990769 proximal neuron projection(GO:1990769)
0.6 8.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.6 3.4 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.6 2.2 GO:0045160 myosin I complex(GO:0045160)
0.5 3.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.4 4.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.4 1.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.4 5.1 GO:0044327 dendritic spine head(GO:0044327)
0.4 8.7 GO:0031091 platelet alpha granule(GO:0031091)
0.4 1.1 GO:0005608 laminin-3 complex(GO:0005608)
0.3 1.0 GO:0030312 external encapsulating structure(GO:0030312)
0.3 5.2 GO:0042571 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.3 3.3 GO:0036156 inner dynein arm(GO:0036156)
0.3 1.4 GO:0070826 paraferritin complex(GO:0070826)
0.3 11.4 GO:0008305 integrin complex(GO:0008305)
0.3 3.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 4.0 GO:0070938 contractile ring(GO:0070938)
0.2 22.0 GO:0014704 intercalated disc(GO:0014704)
0.2 2.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 5.1 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.2 22.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 17.7 GO:0016363 nuclear matrix(GO:0016363)
0.2 3.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 1.9 GO:0097470 ribbon synapse(GO:0097470)
0.1 4.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.6 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 3.3 GO:0043218 compact myelin(GO:0043218)
0.1 3.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 4.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 1.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.0 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 3.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.9 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.1 2.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 5.0 GO:0031941 filamentous actin(GO:0031941)
0.1 0.3 GO:0071564 SWI/SNF complex(GO:0016514) npBAF complex(GO:0071564)
0.1 15.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 4.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.9 GO:0070822 Sin3-type complex(GO:0070822)
0.1 1.1 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 6.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 2.7 GO:0030990 intraciliary transport particle(GO:0030990)
0.1 6.2 GO:0016605 PML body(GO:0016605)
0.1 18.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.9 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.4 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.7 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 9.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.5 GO:0016592 mediator complex(GO:0016592)
0.0 6.7 GO:0043209 myelin sheath(GO:0043209)
0.0 1.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 4.3 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.1 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.8 GO:0005903 brush border(GO:0005903)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.0 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.6 GO:0060170 ciliary membrane(GO:0060170)
0.0 2.8 GO:0001650 fibrillar center(GO:0001650)
0.0 0.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 5.8 GO:0000785 chromatin(GO:0000785)
0.0 0.2 GO:0000930 gamma-tubulin complex(GO:0000930)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 16.9 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
2.3 9.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
2.3 6.9 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
2.1 6.2 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
1.7 11.8 GO:0001851 complement component C3b binding(GO:0001851)
1.6 15.6 GO:0031014 troponin T binding(GO:0031014)
1.3 12.0 GO:0033691 sialic acid binding(GO:0033691)
1.3 21.1 GO:0008301 DNA binding, bending(GO:0008301)
1.2 6.2 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
1.2 5.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
1.2 5.8 GO:0038181 bile acid receptor activity(GO:0038181)
1.1 6.6 GO:0004111 creatine kinase activity(GO:0004111)
1.1 22.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
1.1 3.3 GO:0004998 transferrin receptor activity(GO:0004998)
1.0 4.0 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.9 4.5 GO:0005499 vitamin D binding(GO:0005499)
0.9 4.3 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.8 25.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.7 2.9 GO:0030172 troponin C binding(GO:0030172)
0.7 2.8 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.7 3.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.7 4.7 GO:0030492 hemoglobin binding(GO:0030492)
0.7 2.7 GO:0046923 ER retention sequence binding(GO:0046923)
0.6 5.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.6 4.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.5 3.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.5 1.5 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.5 6.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.5 1.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532) beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.4 1.6 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.4 3.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.4 2.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.4 3.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.4 4.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.4 15.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.3 3.8 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.3 3.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.3 4.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.3 3.4 GO:0031432 titin binding(GO:0031432)
0.3 3.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.3 1.4 GO:0015100 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.3 9.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 17.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3 2.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.3 0.8 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.3 4.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 1.7 GO:0019864 IgG binding(GO:0019864)
0.2 2.9 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 5.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 13.8 GO:0015485 cholesterol binding(GO:0015485)
0.2 3.3 GO:0044548 S100 protein binding(GO:0044548)
0.2 1.0 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.2 0.7 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.2 5.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 5.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 4.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2 2.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 2.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.6 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.1 0.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 9.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.9 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 1.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.8 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 2.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 3.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 4.4 GO:0016504 peptidase activator activity(GO:0016504)
0.1 2.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 2.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 1.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.4 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.8 GO:0008527 taste receptor activity(GO:0008527)
0.1 1.8 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 4.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 3.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 15.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 1.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 2.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 2.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.7 GO:0035197 siRNA binding(GO:0035197)
0.1 0.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.2 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 10.1 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.1 3.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 10.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 5.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 2.8 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 1.0 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.0 0.6 GO:0042166 acetylcholine binding(GO:0042166)
0.0 2.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 2.7 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 3.5 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 20.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 2.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 2.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 0.4 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 2.0 GO:0005179 hormone activity(GO:0005179)
0.0 0.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 3.0 GO:0042393 histone binding(GO:0042393)
0.0 0.8 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 1.0 GO:0005178 integrin binding(GO:0005178)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 17.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.5 3.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.4 26.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 12.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 32.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.3 1.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.2 2.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 7.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 3.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 11.7 PID BCR 5PATHWAY BCR signaling pathway
0.1 1.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 4.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 8.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 2.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 3.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.6 PID BARD1 PATHWAY BARD1 signaling events
0.1 12.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.8 PID AURORA B PATHWAY Aurora B signaling
0.1 1.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 1.3 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 1.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 3.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 3.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 6.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 1.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 4.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 13.9 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.7 33.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.5 19.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.4 20.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.4 11.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.4 9.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.4 15.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.4 4.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.3 6.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.3 6.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 2.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 4.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 28.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 7.0 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.2 26.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 4.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 6.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 6.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 11.8 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 3.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 1.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 9.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 2.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 3.3 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 3.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 2.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.3 REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.1 1.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.9 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 2.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 3.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.8 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 2.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.9 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.8 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 4.9 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 1.6 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 3.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation