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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Foxb1

Z-value: 1.25

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Transcription factors associated with Foxb1

Gene Symbol Gene ID Gene Info
Foxb1
ENSMUSG00000059246.4 forkhead box B1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxb1mm10_v2_chr9_-_69760924_69760940-0.661.2e-05Click!

Activity profile of Foxb1 motif

Sorted Z-values of Foxb1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_127898515 9.37 ENSMUST00000047134.7
Sdr9c7
4short chain dehydrogenase/reductase family 9C, member 7
chr19_+_20601958 6.17 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr19_-_20727533 4.53 ENSMUST00000025656.3
Aldh1a7
aldehyde dehydrogenase family 1, subfamily A7
chr7_+_119900099 3.76 ENSMUST00000106516.1
Lyrm1
LYR motif containing 1
chr2_-_94264745 2.99 ENSMUST00000134563.1
E530001K10Rik
RIKEN cDNA E530001K10 gene
chr2_+_58754910 2.87 ENSMUST00000059102.6
Upp2
uridine phosphorylase 2
chr2_+_58755177 2.78 ENSMUST00000102755.3
Upp2
uridine phosphorylase 2
chr3_-_95904683 2.59 ENSMUST00000147962.1
ENSMUST00000036181.8
Car14
carbonic anhydrase 14
chr12_-_84450944 2.42 ENSMUST00000085192.5
Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr3_-_146596588 2.37 ENSMUST00000029836.4
Dnase2b
deoxyribonuclease II beta
chr13_-_12464925 2.21 ENSMUST00000124888.1
Lgals8
lectin, galactose binding, soluble 8
chr7_-_34655500 2.09 ENSMUST00000032709.1
Kctd15
potassium channel tetramerisation domain containing 15
chr17_+_12378603 2.06 ENSMUST00000014578.5
Plg
plasminogen
chr7_+_67655414 2.04 ENSMUST00000107470.1
Ttc23
tetratricopeptide repeat domain 23
chr3_+_96245530 1.81 ENSMUST00000074976.6
Hist2h2aa1
histone cluster 2, H2aa1
chr3_-_96240317 1.78 ENSMUST00000078756.5
Hist2h2aa2
histone cluster 2, H2aa2
chr2_+_55437100 1.73 ENSMUST00000112633.2
ENSMUST00000112632.1
Kcnj3
potassium inwardly-rectifying channel, subfamily J, member 3
chr14_+_48120841 1.66 ENSMUST00000073150.4
Peli2
pellino 2
chr5_+_102481546 1.66 ENSMUST00000112854.1
Arhgap24
Rho GTPase activating protein 24
chr5_-_34187670 1.55 ENSMUST00000042701.6
ENSMUST00000119171.1
Mxd4
Max dimerization protein 4
chr6_+_15185203 1.50 ENSMUST00000154448.1
Foxp2
forkhead box P2
chr2_-_94264713 1.48 ENSMUST00000129661.1
E530001K10Rik
RIKEN cDNA E530001K10 gene
chr17_+_70522083 1.43 ENSMUST00000148486.1
ENSMUST00000133717.1
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr5_+_102481374 1.38 ENSMUST00000094559.2
ENSMUST00000073302.5
Arhgap24
Rho GTPase activating protein 24
chr7_+_27591705 1.37 ENSMUST00000167435.1
Akt2
thymoma viral proto-oncogene 2
chr1_-_179546261 1.37 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr7_+_27591513 1.36 ENSMUST00000108344.2
Akt2
thymoma viral proto-oncogene 2
chrX_+_150594420 1.30 ENSMUST00000112713.2
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr2_-_160859601 1.28 ENSMUST00000103112.1
Zhx3
zinc fingers and homeoboxes 3
chrX_+_101376359 1.27 ENSMUST00000119080.1
Gjb1
gap junction protein, beta 1
chr4_+_102430047 1.27 ENSMUST00000172616.1
Pde4b
phosphodiesterase 4B, cAMP specific
chr1_-_170867761 1.21 ENSMUST00000027974.6
Atf6
activating transcription factor 6
chr10_+_111506286 1.19 ENSMUST00000164773.1
Phlda1
pleckstrin homology-like domain, family A, member 1
chr2_+_137663424 1.18 ENSMUST00000134833.1
Gm14064
predicted gene 14064
chr11_+_78465697 1.11 ENSMUST00000001126.3
Slc46a1
solute carrier family 46, member 1
chr14_-_55643251 1.11 ENSMUST00000120041.1
ENSMUST00000121937.1
ENSMUST00000133707.1
ENSMUST00000002391.8
ENSMUST00000121791.1
Tm9sf1
transmembrane 9 superfamily member 1
chr9_+_47530173 1.11 ENSMUST00000114548.1
ENSMUST00000152459.1
ENSMUST00000143026.1
ENSMUST00000085909.2
ENSMUST00000114547.1
ENSMUST00000034581.3
Cadm1
cell adhesion molecule 1
chr17_+_34969912 1.07 ENSMUST00000173680.1
Gm20481
predicted gene 20481
chr7_+_19228334 1.06 ENSMUST00000063976.8
Opa3
optic atrophy 3
chr6_+_8948608 1.01 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chr10_-_96409038 1.00 ENSMUST00000179683.1
Gm20091
predicted gene, 20091
chr1_+_25830657 0.98 ENSMUST00000064487.1
Gm9884
predicted gene 9884
chr8_-_45294854 0.97 ENSMUST00000116473.2
Klkb1
kallikrein B, plasma 1
chr13_-_18031616 0.97 ENSMUST00000099736.2
Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr4_-_135494499 0.96 ENSMUST00000105856.2
Nipal3
NIPA-like domain containing 3
chr15_+_43477213 0.93 ENSMUST00000022962.6
Emc2
ER membrane protein complex subunit 2
chr6_+_14901344 0.90 ENSMUST00000115477.1
Foxp2
forkhead box P2
chrX_+_57212110 0.88 ENSMUST00000033466.1
Cd40lg
CD40 ligand
chr5_+_3657172 0.84 ENSMUST00000115515.1
4930511M11Rik
RIKEN cDNA 4930511M11 gene
chr10_+_60106452 0.84 ENSMUST00000165024.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr13_+_40859768 0.81 ENSMUST00000110191.2
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr5_+_104170676 0.81 ENSMUST00000112771.1
Dspp
dentin sialophosphoprotein
chr13_-_83729544 0.78 ENSMUST00000181705.1
Gm26803
predicted gene, 26803
chr2_-_134554348 0.75 ENSMUST00000028704.2
Hao1
hydroxyacid oxidase 1, liver
chr4_+_139653538 0.73 ENSMUST00000030510.7
ENSMUST00000166773.1
Tas1r2
taste receptor, type 1, member 2
chr19_+_5041337 0.72 ENSMUST00000116567.2
Brms1
breast cancer metastasis-suppressor 1
chr1_-_120120138 0.72 ENSMUST00000112648.1
ENSMUST00000128408.1
Dbi
diazepam binding inhibitor
chrX_+_109095359 0.71 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr6_-_123650635 0.68 ENSMUST00000170808.1
Vmn2r22
vomeronasal 2, receptor 22
chr6_+_90122643 0.68 ENSMUST00000174204.1
Vmn1r51
vomeronasal 1 receptor 51
chr8_+_94037198 0.66 ENSMUST00000109556.2
ENSMUST00000093301.2
ENSMUST00000060632.7
Ogfod1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr10_+_38965515 0.65 ENSMUST00000019992.5
Lama4
laminin, alpha 4
chr16_-_34095983 0.65 ENSMUST00000114973.1
ENSMUST00000114964.1
Kalrn
kalirin, RhoGEF kinase
chr8_-_121083085 0.65 ENSMUST00000182264.1
Fendrr
Foxf1 adjacent non-coding developmental regulatory RNA
chr11_-_98329641 0.64 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chr12_-_31950170 0.64 ENSMUST00000176520.1
Hbp1
high mobility group box transcription factor 1
chr4_-_135494615 0.64 ENSMUST00000102549.3
Nipal3
NIPA-like domain containing 3
chr5_-_51567717 0.61 ENSMUST00000127135.1
ENSMUST00000151104.1
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr5_-_87482258 0.57 ENSMUST00000079811.6
ENSMUST00000144144.1
Ugt2a1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr5_-_88527841 0.57 ENSMUST00000087033.3
Igj
immunoglobulin joining chain
chr10_+_69925954 0.57 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3
ankyrin 3, epithelial
chr5_-_108795352 0.56 ENSMUST00000004943.1
Tmed11
transmembrane emp24 protein transport domain containing
chr6_-_136922169 0.55 ENSMUST00000032343.6
Erp27
endoplasmic reticulum protein 27
chr12_-_31950535 0.54 ENSMUST00000172314.2
Hbp1
high mobility group box transcription factor 1
chr10_+_69925766 0.53 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3
ankyrin 3, epithelial
chr12_-_40199315 0.53 ENSMUST00000095760.2
Lsmem1
leucine-rich single-pass membrane protein 1
chr1_-_72536930 0.53 ENSMUST00000047786.5
March4
membrane-associated ring finger (C3HC4) 4
chr18_-_43687695 0.51 ENSMUST00000082254.6
Jakmip2
janus kinase and microtubule interacting protein 2
chr10_+_69925800 0.50 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chr12_-_31950210 0.49 ENSMUST00000176084.1
ENSMUST00000176103.1
ENSMUST00000167458.2
Hbp1
high mobility group box transcription factor 1
chr6_+_14901440 0.49 ENSMUST00000128567.1
Foxp2
forkhead box P2
chr17_+_70522149 0.48 ENSMUST00000140728.1
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr14_-_41185188 0.47 ENSMUST00000077136.3
Sftpd
surfactant associated protein D
chr7_+_24271568 0.44 ENSMUST00000032696.6
Zfp93
zinc finger protein 93
chr2_-_147186389 0.44 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2
NK2 homeobox 2
chr1_-_75046639 0.44 ENSMUST00000152855.1
Nhej1
nonhomologous end-joining factor 1
chr16_-_44333135 0.42 ENSMUST00000047446.6
Sidt1
SID1 transmembrane family, member 1
chr4_+_32243733 0.41 ENSMUST00000165661.1
D130062J21Rik
RIKEN cDNA D130062J21 gene
chr14_-_51256112 0.40 ENSMUST00000061936.6
Ear11
eosinophil-associated, ribonuclease A family, member 11
chr5_-_75044562 0.39 ENSMUST00000075452.5
Chic2
cysteine-rich hydrophobic domain 2
chr10_-_61979073 0.39 ENSMUST00000105453.1
ENSMUST00000105452.2
ENSMUST00000105454.2
Col13a1
collagen, type XIII, alpha 1
chr2_+_30061754 0.39 ENSMUST00000149578.1
ENSMUST00000102866.3
Set
SET nuclear oncogene
chr6_+_92940572 0.38 ENSMUST00000181145.1
ENSMUST00000181840.1
9530026P05Rik
RIKEN cDNA 9530026P05 gene
chr16_-_44332925 0.38 ENSMUST00000136381.1
Sidt1
SID1 transmembrane family, member 1
chr3_-_129804030 0.38 ENSMUST00000179187.1
Lrit3
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
chr3_-_33082004 0.36 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr18_+_36952621 0.34 ENSMUST00000115661.2
Pcdha2
protocadherin alpha 2
chr13_+_83738874 0.34 ENSMUST00000052354.4
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr1_+_81077204 0.34 ENSMUST00000123720.1
Nyap2
neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
chr1_-_156034826 0.33 ENSMUST00000141878.1
ENSMUST00000123705.1
Tor1aip1
torsin A interacting protein 1
chr9_-_101198999 0.31 ENSMUST00000066773.7
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr2_-_176917518 0.31 ENSMUST00000108931.2
Gm14296
predicted gene 14296
chr1_-_39805311 0.31 ENSMUST00000171319.2
Gm3646
predicted gene 3646
chr3_-_146781351 0.30 ENSMUST00000005164.7
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr4_-_139833524 0.29 ENSMUST00000030508.7
Pax7
paired box gene 7
chr4_+_11579647 0.29 ENSMUST00000180239.1
Fsbp
fibrinogen silencer binding protein
chr10_+_69925484 0.29 ENSMUST00000182692.1
ENSMUST00000092433.5
Ank3
ankyrin 3, epithelial
chr2_+_181767040 0.29 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr4_+_109235413 0.26 ENSMUST00000106628.1
Calr4
calreticulin 4
chr16_+_17331371 0.26 ENSMUST00000023450.6
ENSMUST00000161034.1
Serpind1
serine (or cysteine) peptidase inhibitor, clade D, member 1
chrX_+_119927196 0.25 ENSMUST00000040961.2
ENSMUST00000113366.1
Pabpc5
poly(A) binding protein, cytoplasmic 5
chr3_-_155055341 0.25 ENSMUST00000064076.3
Tnni3k
TNNI3 interacting kinase
chr7_-_109960385 0.24 ENSMUST00000106722.1
Dennd5a
DENN/MADD domain containing 5A
chr1_+_179960472 0.24 ENSMUST00000097453.2
ENSMUST00000111117.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr2_+_181767283 0.20 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr2_+_153900374 0.18 ENSMUST00000088955.5
ENSMUST00000135501.1
Bpifb6
BPI fold containing family B, member 6
chr4_+_99656299 0.18 ENSMUST00000087285.3
Foxd3
forkhead box D3
chr6_+_34863130 0.17 ENSMUST00000074949.3
Tmem140
transmembrane protein 140
chr15_-_55548164 0.16 ENSMUST00000165356.1
Mrpl13
mitochondrial ribosomal protein L13
chr7_+_29071597 0.14 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr7_-_109960461 0.14 ENSMUST00000080437.6
Dennd5a
DENN/MADD domain containing 5A
chr5_-_107687990 0.13 ENSMUST00000180428.1
Gm26692
predicted gene, 26692
chr14_+_55222005 0.12 ENSMUST00000022820.5
Dhrs2
dehydrogenase/reductase member 2
chr11_+_87699897 0.12 ENSMUST00000040089.4
Rnf43
ring finger protein 43
chr19_-_9087945 0.11 ENSMUST00000025554.2
Scgb1a1
secretoglobin, family 1A, member 1 (uteroglobin)
chr3_-_123690806 0.11 ENSMUST00000154668.1
Ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr6_+_34709610 0.11 ENSMUST00000031775.6
Cald1
caldesmon 1
chrX_-_43274786 0.10 ENSMUST00000016294.7
Tenm1
teneurin transmembrane protein 1
chrX_+_41401128 0.10 ENSMUST00000115103.2
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr10_+_96616998 0.10 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr7_+_103184803 0.09 ENSMUST00000106893.1
Olfr592
olfactory receptor 592
chr4_-_103026709 0.06 ENSMUST00000084382.5
ENSMUST00000106869.2
Insl5
insulin-like 5
chr4_-_121109199 0.06 ENSMUST00000106268.3
Tmco2
transmembrane and coiled-coil domains 2
chr2_-_60722636 0.06 ENSMUST00000028348.2
ENSMUST00000112517.1
Itgb6
integrin beta 6
chr5_-_137502402 0.02 ENSMUST00000111035.1
ENSMUST00000031728.4
Pop7
processing of precursor 7, ribonuclease P family, (S. cerevisiae)
chr1_+_70725715 0.01 ENSMUST00000053922.5
Vwc2l
von Willebrand factor C domain-containing protein 2-like

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxb1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.8 2.4 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.5 2.5 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.5 2.7 GO:0071486 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.4 1.1 GO:0009826 unidimensional cell growth(GO:0009826)
0.4 2.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.3 3.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.3 4.5 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.3 0.9 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.3 2.6 GO:0015670 carbon dioxide transport(GO:0015670)
0.3 0.8 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.2 1.7 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.2 1.1 GO:0015886 heme transport(GO:0015886)
0.2 0.6 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.2 0.8 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 2.9 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.2 1.9 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.6 GO:1990401 embryonic lung development(GO:1990401)
0.2 0.6 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.2 1.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 1.7 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.4 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 1.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.7 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1 1.9 GO:0070842 aggresome assembly(GO:0070842)
0.1 1.3 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 2.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 0.7 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 0.7 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.8 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 1.7 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.1 1.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.8 GO:0033227 dsRNA transport(GO:0033227)
0.1 1.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 1.6 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.7 GO:0006449 regulation of translational termination(GO:0006449)
0.1 0.6 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.4 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 4.4 GO:0009166 nucleotide catabolic process(GO:0009166)
0.0 0.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 3.6 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.5 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 1.3 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.4 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.4 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.4 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.4 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.7 GO:0045098 type III intermediate filament(GO:0045098)
0.5 2.1 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.4 1.3 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 2.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.4 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 1.1 GO:0070852 cell body fiber(GO:0070852)
0.1 0.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.3 GO:0005922 connexon complex(GO:0005922)
0.0 1.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.4 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.7 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.7 GO:0005605 basal lamina(GO:0005605)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 1.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.4 GO:0030496 midbody(GO:0030496)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.5 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 1.1 GO:0031526 brush border membrane(GO:0031526)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
1.1 5.7 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.6 2.4 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.4 9.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.3 1.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3 1.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 1.1 GO:0015232 heme transporter activity(GO:0015232)
0.2 0.7 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.2 0.8 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 0.8 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.2 1.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 2.1 GO:1990405 protein antigen binding(GO:1990405)
0.2 2.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.8 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 1.3 GO:0005243 gap junction channel activity(GO:0005243)
0.1 1.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.7 GO:0008527 taste receptor activity(GO:0008527)
0.1 1.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.7 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.0 2.4 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 4.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 2.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 3.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 2.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.7 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 5.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.2 2.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.7 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 2.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 3.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.1 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.4 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription