Project

avrg: GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Foxc2

Z-value: 1.15

Motif logo

logo of

Transcription factors associated with Foxc2

Gene Symbol Gene ID Gene Info
Foxc2
ENSMUSG00000046714.6 forkhead box C2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxc2mm10_v2_chr8_+_121116163_1211161770.086.5e-01Click!

Activity profile of Foxc2 motif

Sorted Z-values of Foxc2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_113258837 16.18 ENSMUST00000098673.3
Amy2a5
amylase 2a5
chr3_-_20275659 16.07 ENSMUST00000011607.5
Cpb1
carboxypeptidase B1 (tissue)
chr6_+_30541582 15.55 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr3_-_113532288 12.90 ENSMUST00000132353.1
Amy2a1
amylase 2a1
chr17_-_31144271 8.05 ENSMUST00000024826.7
Tff2
trefoil factor 2 (spasmolytic protein 1)
chr2_-_62483637 5.30 ENSMUST00000136686.1
ENSMUST00000102733.3
Gcg
glucagon
chr6_+_142298419 5.12 ENSMUST00000041993.2
Iapp
islet amyloid polypeptide
chr6_-_136922169 4.58 ENSMUST00000032343.6
Erp27
endoplasmic reticulum protein 27
chr3_+_107230608 3.53 ENSMUST00000179399.1
A630076J17Rik
RIKEN cDNA A630076J17 gene
chr5_-_108795352 3.15 ENSMUST00000004943.1
Tmed11
transmembrane emp24 protein transport domain containing
chr17_-_12675833 2.90 ENSMUST00000024596.8
Slc22a1
solute carrier family 22 (organic cation transporter), member 1
chr2_+_58755177 2.57 ENSMUST00000102755.3
Upp2
uridine phosphorylase 2
chr10_+_127898515 2.46 ENSMUST00000047134.7
Sdr9c7
4short chain dehydrogenase/reductase family 9C, member 7
chr2_+_58754910 2.26 ENSMUST00000059102.6
Upp2
uridine phosphorylase 2
chr1_+_130865669 1.92 ENSMUST00000038829.5
Faim3
Fas apoptotic inhibitory molecule 3
chr19_-_58455903 1.87 ENSMUST00000131877.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr17_+_47726834 1.84 ENSMUST00000024782.5
ENSMUST00000144955.1
Pgc
progastricsin (pepsinogen C)
chr19_-_58455161 1.83 ENSMUST00000135730.1
ENSMUST00000152507.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr10_-_61979073 1.50 ENSMUST00000105453.1
ENSMUST00000105452.2
ENSMUST00000105454.2
Col13a1
collagen, type XIII, alpha 1
chr11_-_68386974 1.49 ENSMUST00000135141.1
Ntn1
netrin 1
chr19_-_58455398 1.47 ENSMUST00000026076.7
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr1_-_130661584 1.45 ENSMUST00000137276.2
C4bp
complement component 4 binding protein
chr9_+_55326913 1.43 ENSMUST00000085754.3
ENSMUST00000034862.4
AI118078
expressed sequence AI118078
chr17_+_12378603 1.41 ENSMUST00000014578.5
Plg
plasminogen
chr11_-_68386821 1.37 ENSMUST00000021284.3
Ntn1
netrin 1
chr10_+_87861309 1.37 ENSMUST00000122100.1
Igf1
insulin-like growth factor 1
chr10_-_68278713 1.33 ENSMUST00000020106.7
Arid5b
AT rich interactive domain 5B (MRF1-like)
chr16_-_29378667 1.28 ENSMUST00000143373.1
ENSMUST00000075806.4
Atp13a5
ATPase type 13A5
chr10_-_41611319 1.27 ENSMUST00000179614.1
Ccdc162
coiled-coil domain containing 162
chr1_-_130661613 1.25 ENSMUST00000027657.7
C4bp
complement component 4 binding protein
chr8_-_84773381 1.14 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr6_-_83536215 1.09 ENSMUST00000075161.5
Actg2
actin, gamma 2, smooth muscle, enteric
chr3_+_63295815 1.07 ENSMUST00000029400.1
Mme
membrane metallo endopeptidase
chr12_-_80968075 1.04 ENSMUST00000095572.4
Slc10a1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr18_+_69925466 1.00 ENSMUST00000043929.4
Ccdc68
coiled-coil domain containing 68
chr16_-_45492962 0.96 ENSMUST00000114585.2
Gm609
predicted gene 609
chr14_-_61258484 0.96 ENSMUST00000077954.5
Sgcg
sarcoglycan, gamma (dystrophin-associated glycoprotein)
chr6_-_142322978 0.92 ENSMUST00000081380.3
Slco1a5
solute carrier organic anion transporter family, member 1a5
chr18_+_69925542 0.92 ENSMUST00000080050.5
Ccdc68
coiled-coil domain containing 68
chr6_+_17491216 0.91 ENSMUST00000080469.5
Met
met proto-oncogene
chr13_-_103920295 0.90 ENSMUST00000169083.1
Erbb2ip
Erbb2 interacting protein
chr12_-_103657095 0.89 ENSMUST00000152517.1
Serpina6
serine (or cysteine) peptidase inhibitor, clade A, member 6
chr9_+_123806468 0.82 ENSMUST00000049810.7
Cxcr6
chemokine (C-X-C motif) receptor 6
chr13_+_40859768 0.81 ENSMUST00000110191.2
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr9_+_70207342 0.77 ENSMUST00000034745.7
Myo1e
myosin IE
chr8_-_121083085 0.75 ENSMUST00000182264.1
Fendrr
Foxf1 adjacent non-coding developmental regulatory RNA
chr12_-_103657159 0.74 ENSMUST00000044159.6
Serpina6
serine (or cysteine) peptidase inhibitor, clade A, member 6
chr1_-_179546261 0.74 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr16_+_43363855 0.73 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chrX_+_57212110 0.73 ENSMUST00000033466.1
Cd40lg
CD40 ligand
chr18_-_74961252 0.73 ENSMUST00000066532.4
Lipg
lipase, endothelial
chr4_+_150853919 0.72 ENSMUST00000073600.2
Errfi1
ERBB receptor feedback inhibitor 1
chr3_-_146596588 0.67 ENSMUST00000029836.4
Dnase2b
deoxyribonuclease II beta
chr2_+_4718145 0.67 ENSMUST00000056914.6
Bend7
BEN domain containing 7
chr16_-_43664145 0.67 ENSMUST00000096065.4
Tigit
T cell immunoreceptor with Ig and ITIM domains
chr15_-_5108469 0.67 ENSMUST00000141020.1
Card6
caspase recruitment domain family, member 6
chr10_+_60106452 0.66 ENSMUST00000165024.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr11_+_77765588 0.66 ENSMUST00000164315.1
Myo18a
myosin XVIIIA
chr2_-_110305730 0.65 ENSMUST00000046233.2
Bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr1_-_156035891 0.64 ENSMUST00000126448.1
Tor1aip1
torsin A interacting protein 1
chr11_-_107348130 0.62 ENSMUST00000134763.1
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr7_+_27195781 0.61 ENSMUST00000108379.1
ENSMUST00000179391.1
BC024978
cDNA sequence BC024978
chr8_+_45658666 0.58 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2
sorbin and SH3 domain containing 2
chr1_-_97977233 0.58 ENSMUST00000161567.1
Pam
peptidylglycine alpha-amidating monooxygenase
chr8_+_45658731 0.57 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2
sorbin and SH3 domain containing 2
chr2_-_176917518 0.56 ENSMUST00000108931.2
Gm14296
predicted gene 14296
chr12_-_108003414 0.55 ENSMUST00000109887.1
ENSMUST00000109891.2
Bcl11b
B cell leukemia/lymphoma 11B
chr7_+_67655414 0.54 ENSMUST00000107470.1
Ttc23
tetratricopeptide repeat domain 23
chr5_-_51567717 0.54 ENSMUST00000127135.1
ENSMUST00000151104.1
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr5_+_102481374 0.54 ENSMUST00000094559.2
ENSMUST00000073302.5
Arhgap24
Rho GTPase activating protein 24
chr6_-_40951826 0.53 ENSMUST00000073642.5
Gm4744
predicted gene 4744
chr9_+_47530173 0.53 ENSMUST00000114548.1
ENSMUST00000152459.1
ENSMUST00000143026.1
ENSMUST00000085909.2
ENSMUST00000114547.1
ENSMUST00000034581.3
Cadm1
cell adhesion molecule 1
chrX_+_150594420 0.52 ENSMUST00000112713.2
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr19_+_44992127 0.52 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr12_-_57546121 0.52 ENSMUST00000044380.6
Foxa1
forkhead box A1
chr5_+_102481546 0.51 ENSMUST00000112854.1
Arhgap24
Rho GTPase activating protein 24
chr4_+_34893772 0.42 ENSMUST00000029975.3
ENSMUST00000135871.1
ENSMUST00000108130.1
Cga
glycoprotein hormones, alpha subunit
chr6_+_34709610 0.41 ENSMUST00000031775.6
Cald1
caldesmon 1
chr2_+_91730127 0.41 ENSMUST00000099712.3
ENSMUST00000111317.2
ENSMUST00000111316.2
ENSMUST00000045705.7
Ambra1
autophagy/beclin 1 regulator 1
chr13_-_12464925 0.41 ENSMUST00000124888.1
Lgals8
lectin, galactose binding, soluble 8
chr11_+_78465697 0.40 ENSMUST00000001126.3
Slc46a1
solute carrier family 46, member 1
chr10_+_38965515 0.38 ENSMUST00000019992.5
Lama4
laminin, alpha 4
chr11_-_69662564 0.38 ENSMUST00000129224.1
ENSMUST00000155200.1
Mpdu1
mannose-P-dolichol utilization defect 1
chr1_-_156036473 0.37 ENSMUST00000097527.3
ENSMUST00000027738.7
Tor1aip1
torsin A interacting protein 1
chr4_+_102741287 0.37 ENSMUST00000097948.2
Sgip1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr15_-_5108492 0.36 ENSMUST00000118365.2
Card6
caspase recruitment domain family, member 6
chr8_-_45294854 0.35 ENSMUST00000116473.2
Klkb1
kallikrein B, plasma 1
chr2_+_76675265 0.35 ENSMUST00000111920.1
Plekha3
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 3
chr7_+_113765998 0.34 ENSMUST00000046687.9
Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr4_+_97777606 0.34 ENSMUST00000075448.6
ENSMUST00000092532.6
Nfia
nuclear factor I/A
chr6_+_15185203 0.33 ENSMUST00000154448.1
Foxp2
forkhead box P2
chr1_+_156035705 0.31 ENSMUST00000111754.2
ENSMUST00000133152.1
Tor1aip2
torsin A interacting protein 2
chr1_+_156036133 0.31 ENSMUST00000128941.1
Tor1aip2
torsin A interacting protein 2
chr2_-_60673654 0.30 ENSMUST00000059888.8
ENSMUST00000154764.1
Itgb6
integrin beta 6
chr3_+_3634145 0.30 ENSMUST00000108394.1
Hnf4g
hepatocyte nuclear factor 4, gamma
chr11_+_32000452 0.30 ENSMUST00000020537.2
ENSMUST00000109409.1
Nsg2
neuron specific gene family member 2
chr4_+_102430047 0.30 ENSMUST00000172616.1
Pde4b
phosphodiesterase 4B, cAMP specific
chr13_-_107890059 0.29 ENSMUST00000105097.2
Zswim6
zinc finger SWIM-type containing 6
chr4_+_99656299 0.27 ENSMUST00000087285.3
Foxd3
forkhead box D3
chr13_+_42681513 0.27 ENSMUST00000149235.1
Phactr1
phosphatase and actin regulator 1
chr5_-_87482258 0.26 ENSMUST00000079811.6
ENSMUST00000144144.1
Ugt2a1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr7_+_24271568 0.25 ENSMUST00000032696.6
Zfp93
zinc finger protein 93
chr2_-_77519565 0.25 ENSMUST00000111830.2
Zfp385b
zinc finger protein 385B
chr16_-_34263179 0.24 ENSMUST00000114949.1
ENSMUST00000114954.1
Kalrn
kalirin, RhoGEF kinase
chr16_+_43364145 0.23 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr3_+_94837702 0.21 ENSMUST00000107266.1
ENSMUST00000042402.5
ENSMUST00000107269.1
Pogz
pogo transposable element with ZNF domain
chr4_-_34882919 0.21 ENSMUST00000098163.2
ENSMUST00000047950.5
Zfp292
zinc finger protein 292
chr7_+_82175156 0.21 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr10_+_41303968 0.21 ENSMUST00000173517.2
Ak9
adenylate kinase 9
chr10_+_96616998 0.20 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr5_+_16553488 0.19 ENSMUST00000030683.3
Hgf
hepatocyte growth factor
chr2_+_73312601 0.18 ENSMUST00000090811.4
ENSMUST00000112050.1
Scrn3
secernin 3
chr6_+_147032528 0.18 ENSMUST00000036194.4
Rep15
RAB15 effector protein
chr12_+_71016658 0.15 ENSMUST00000125125.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr1_+_87404916 0.15 ENSMUST00000173152.1
ENSMUST00000173663.1
Gigyf2
GRB10 interacting GYF protein 2
chr14_-_24486994 0.15 ENSMUST00000026322.7
Polr3a
polymerase (RNA) III (DNA directed) polypeptide A
chr3_+_94837533 0.14 ENSMUST00000107270.2
Pogz
pogo transposable element with ZNF domain
chr9_+_13619990 0.14 ENSMUST00000159294.1
Maml2
mastermind like 2 (Drosophila)
chr14_+_48120841 0.14 ENSMUST00000073150.4
Peli2
pellino 2
chr8_-_47713920 0.13 ENSMUST00000038738.5
Cdkn2aip
CDKN2A interacting protein
chr8_-_64205970 0.13 ENSMUST00000066166.4
Tll1
tolloid-like
chr1_+_156838915 0.12 ENSMUST00000111720.1
Angptl1
angiopoietin-like 1
chr19_+_20405280 0.12 ENSMUST00000179640.1
1500015L24Rik
RIKEN cDNA 1500015L24 gene
chr16_+_17331371 0.12 ENSMUST00000023450.6
ENSMUST00000161034.1
Serpind1
serine (or cysteine) peptidase inhibitor, clade D, member 1
chr5_+_43515513 0.12 ENSMUST00000167522.1
ENSMUST00000144558.1
ENSMUST00000076939.6
C1qtnf7
C1q and tumor necrosis factor related protein 7
chr16_-_34262945 0.10 ENSMUST00000114953.1
Kalrn
kalirin, RhoGEF kinase
chr6_+_14901344 0.10 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr2_-_51973219 0.09 ENSMUST00000028314.2
Nmi
N-myc (and STAT) interactor
chr19_+_56461629 0.09 ENSMUST00000178590.1
ENSMUST00000039666.6
Plekhs1
pleckstrin homology domain containing, family S member 1
chr8_-_84237042 0.09 ENSMUST00000039480.5
Zswim4
zinc finger SWIM-type containing 4
chr8_-_45262012 0.09 ENSMUST00000034064.3
F11
coagulation factor XI
chr14_-_55643251 0.09 ENSMUST00000120041.1
ENSMUST00000121937.1
ENSMUST00000133707.1
ENSMUST00000002391.8
ENSMUST00000121791.1
Tm9sf1
transmembrane 9 superfamily member 1
chr7_+_113766119 0.08 ENSMUST00000084696.4
Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr17_+_34969912 0.08 ENSMUST00000173680.1
Gm20481
predicted gene 20481
chr11_+_87699897 0.07 ENSMUST00000040089.4
Rnf43
ring finger protein 43
chr2_-_51972990 0.07 ENSMUST00000145481.1
ENSMUST00000112705.2
Nmi
N-myc (and STAT) interactor
chr4_-_139833524 0.07 ENSMUST00000030508.7
Pax7
paired box gene 7
chr5_+_91027457 0.06 ENSMUST00000041516.8
Epgn
epithelial mitogen
chr4_+_48049080 0.06 ENSMUST00000153369.1
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr7_+_44849581 0.04 ENSMUST00000150335.1
ENSMUST00000107882.1
Akt1s1
AKT1 substrate 1 (proline-rich)
chr18_+_34758890 0.02 ENSMUST00000049281.5
Fam53c
family with sequence similarity 53, member C
chr13_-_78196373 0.02 ENSMUST00000125176.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr4_-_118409219 0.02 ENSMUST00000075406.5
Szt2
seizure threshold 2
chr1_-_18145895 0.02 ENSMUST00000026876.6
ENSMUST00000115344.1
Crisp4
cysteine-rich secretory protein 4
chr5_-_72642725 0.01 ENSMUST00000087213.5
Cnga1
cyclic nucleotide gated channel alpha 1
chr3_+_125404292 0.01 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chrX_-_94123087 0.01 ENSMUST00000113925.1
Zfx
zinc finger protein X-linked
chr12_-_101958148 0.01 ENSMUST00000159883.1
ENSMUST00000160251.1
ENSMUST00000161011.1
ENSMUST00000021606.5
Atxn3
ataxin 3
chr9_+_44072196 0.01 ENSMUST00000176671.1
Usp2
ubiquitin specific peptidase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxc2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 8.0 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.8 5.3 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.7 2.9 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.6 5.1 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.4 1.8 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.4 1.8 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.4 2.9 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.4 1.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.2 0.7 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.2 1.9 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.2 0.8 GO:1990401 embryonic lung development(GO:1990401)
0.2 0.7 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.2 0.5 GO:0009826 unidimensional cell growth(GO:0009826)
0.2 0.7 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.2 0.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 1.3 GO:0060613 fat pad development(GO:0060613)
0.1 0.4 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 0.7 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1 0.5 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.1 0.9 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 1.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.8 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.7 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.4 GO:0015886 heme transport(GO:0015886)
0.1 0.8 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 1.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.6 GO:0031179 peptide modification(GO:0031179)
0.1 1.1 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.8 GO:0072310 glomerular basement membrane development(GO:0032836) glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 0.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.6 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.1 0.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.2 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1 0.2 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.0 0.6 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.3 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.3 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.7 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 5.1 GO:0009166 nucleotide catabolic process(GO:0009166)
0.0 0.4 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.4 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 1.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.4 GO:0051382 kinetochore assembly(GO:0051382)
0.0 1.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 3.3 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0 0.1 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.0 0.8 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.0 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.0 0.4 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0033572 transferrin transport(GO:0033572)
0.0 25.5 GO:0006508 proteolysis(GO:0006508)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.8 GO:0045098 type III intermediate filament(GO:0045098)
0.4 1.4 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.2 0.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 1.4 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) insulin-like growth factor ternary complex(GO:0042567)
0.1 0.3 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.8 GO:0032437 cuticular plate(GO:0032437)
0.1 1.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 2.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 71.7 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0070852 cell body fiber(GO:0070852)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 2.6 GO:0005903 brush border(GO:0005903)
0.0 2.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.5 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 16.2 GO:0004556 alpha-amylase activity(GO:0004556)
1.0 4.8 GO:0004850 uridine phosphorylase activity(GO:0004850)
1.0 2.9 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.9 30.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.6 8.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 0.9 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 0.8 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 0.7 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 0.7 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 1.0 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.6 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.8 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.1 0.7 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 1.4 GO:1990405 protein antigen binding(GO:1990405)
0.1 2.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.8 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 11.4 GO:0005179 hormone activity(GO:0005179)
0.1 0.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.1 0.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 1.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 5.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 1.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.3 GO:0008238 exopeptidase activity(GO:0008238)
0.0 0.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0043531 ADP binding(GO:0043531)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 2.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 4.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.9 PID IGF1 PATHWAY IGF1 pathway
0.0 1.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.3 4.9 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 2.9 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 2.9 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 5.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 5.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.4 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.9 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex