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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Foxf1

Z-value: 1.56

Motif logo

Transcription factors associated with Foxf1

Gene Symbol Gene ID Gene Info
ENSMUSG00000042812.4 forkhead box F1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxf1mm10_v2_chr8_+_121084352_121084474-0.625.4e-05Click!

Activity profile of Foxf1 motif

Sorted Z-values of Foxf1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_68117713 9.72 ENSMUST00000112346.2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr17_-_12675833 8.41 ENSMUST00000024596.8
solute carrier family 22 (organic cation transporter), member 1
chr10_-_41579207 8.22 ENSMUST00000095227.3
coiled-coil domain containing 162
chr9_-_48605147 7.09 ENSMUST00000034808.5
ENSMUST00000119426.1
nicotinamide N-methyltransferase
chr15_+_4727175 6.26 ENSMUST00000162585.1
complement component 6
chr15_+_4727202 6.12 ENSMUST00000161997.1
ENSMUST00000022788.8
complement component 6
chr15_+_4727265 5.97 ENSMUST00000162350.1
complement component 6
chr16_+_91269759 5.31 ENSMUST00000056882.5
oligodendrocyte transcription factor 1
chr1_-_130661584 5.31 ENSMUST00000137276.2
complement component 4 binding protein
chr1_-_130661613 5.27 ENSMUST00000027657.7
complement component 4 binding protein
chr9_+_55326913 4.81 ENSMUST00000085754.3
ENSMUST00000034862.4
expressed sequence AI118078
chr7_-_100656953 4.05 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
pleckstrin homology domain containing, family B (evectins) member 1
chr12_-_103657159 4.04 ENSMUST00000044159.6
serine (or cysteine) peptidase inhibitor, clade A, member 6
chr19_+_20405280 3.89 ENSMUST00000179640.1
RIKEN cDNA 1500015L24 gene
chr8_+_45658666 3.81 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
sorbin and SH3 domain containing 2
chr6_-_59024470 3.77 ENSMUST00000089860.5
family with sequence similarity 13, member A
chr2_+_68104671 3.61 ENSMUST00000042456.3
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr19_+_30232921 3.59 ENSMUST00000025797.5
mannose-binding lectin (protein C) 2
chr18_-_38929148 3.56 ENSMUST00000134864.1
fibroblast growth factor 1
chr1_-_139560158 3.55 ENSMUST00000160423.1
ENSMUST00000023965.5
complement factor H-related 1
chr9_+_53301571 3.54 ENSMUST00000051014.1
exophilin 5
chr8_-_84773381 3.52 ENSMUST00000109764.1
nuclear factor I/X
chr12_-_103904887 3.45 ENSMUST00000074051.5
serine (or cysteine) peptidase inhibitor, clade A, member 1C
chr4_+_104766334 3.41 ENSMUST00000065072.6
complement component 8, beta polypeptide
chr4_+_104766308 3.38 ENSMUST00000031663.3
complement component 8, beta polypeptide
chr17_+_79626669 3.24 ENSMUST00000086570.1
RIKEN cDNA 4921513D11 gene
chr19_-_58455161 3.15 ENSMUST00000135730.1
ENSMUST00000152507.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr12_-_103773592 3.14 ENSMUST00000078869.5
serine (or cysteine) peptidase inhibitor, clade A, member 1D
chr18_+_51117754 3.13 ENSMUST00000116639.2
proline rich 16
chr1_-_139781236 3.12 ENSMUST00000027612.8
ENSMUST00000111989.2
ENSMUST00000111986.2
predicted gene 4788
chr12_-_103657095 3.09 ENSMUST00000152517.1
serine (or cysteine) peptidase inhibitor, clade A, member 6
chr9_+_7445822 3.06 ENSMUST00000034497.6
matrix metallopeptidase 3
chr19_-_58455398 3.01 ENSMUST00000026076.7
glial cell line derived neurotrophic factor family receptor alpha 1
chr6_-_142322978 2.96 ENSMUST00000081380.3
solute carrier organic anion transporter family, member 1a5
chr19_-_58455903 2.96 ENSMUST00000131877.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr17_+_28858411 2.91 ENSMUST00000114737.1
ENSMUST00000056866.5
patatin-like phospholipase domain containing 1
chr16_+_43363855 2.88 ENSMUST00000156367.1
zinc finger and BTB domain containing 20
chr5_+_88583527 2.80 ENSMUST00000031229.6
RUN and FYVE domain containing 3
chr4_-_57916283 2.68 ENSMUST00000063816.5
RIKEN cDNA D630039A03 gene
chr2_+_58755177 2.64 ENSMUST00000102755.3
uridine phosphorylase 2
chr13_+_23870259 2.64 ENSMUST00000110413.1
solute carrier family 17 (sodium phosphate), member 1
chr2_-_86347764 2.62 ENSMUST00000099894.2
olfactory receptor 1055
chr2_+_58754910 2.62 ENSMUST00000059102.6
uridine phosphorylase 2
chr16_+_43364145 2.60 ENSMUST00000148775.1
zinc finger and BTB domain containing 20
chr8_+_45658731 2.58 ENSMUST00000143820.1
ENSMUST00000132139.1
sorbin and SH3 domain containing 2
chr18_-_38918642 2.49 ENSMUST00000040647.4
fibroblast growth factor 1
chr1_+_67123015 2.45 ENSMUST00000027144.7
carbamoyl-phosphate synthetase 1
chr6_-_59024340 2.43 ENSMUST00000173193.1
family with sequence similarity 13, member A
chr17_+_36958571 2.41 ENSMUST00000040177.6
Znrd1 antisense
chr2_+_72054598 2.40 ENSMUST00000028525.5
Rap guanine nucleotide exchange factor (GEF) 4
chr7_-_34655500 2.37 ENSMUST00000032709.1
potassium channel tetramerisation domain containing 15
chr11_-_69805617 2.37 ENSMUST00000051025.4
transmembrane protein 102
chrX_+_142228177 2.37 ENSMUST00000112914.1
nuclear transport factor 2-like export factor 2
chr17_+_12584183 2.34 ENSMUST00000046959.7
solute carrier family 22 (organic cation transporter), member 2
chr11_-_86993682 2.30 ENSMUST00000018571.4
yippee-like 2 (Drosophila)
chr1_-_139858684 2.27 ENSMUST00000094489.3
complement factor H-related 2
chr15_+_75216592 2.24 ENSMUST00000055719.6
cDNA sequence BC025446
chr6_+_129533183 2.24 ENSMUST00000032264.6
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr14_-_30353468 2.16 ENSMUST00000112249.1
calcium channel, voltage-dependent, L type, alpha 1D subunit
chrX_+_142227923 2.11 ENSMUST00000042329.5
nuclear transport factor 2-like export factor 2
chr1_+_130865669 2.01 ENSMUST00000038829.5
Fas apoptotic inhibitory molecule 3
chr4_-_6275629 1.99 ENSMUST00000029905.1
cytochrome P450, family 7, subfamily a, polypeptide 1
chr5_+_90561102 1.96 ENSMUST00000094615.4
RIKEN cDNA 5830473C10 gene
chr2_+_4718145 1.93 ENSMUST00000056914.6
BEN domain containing 7
chr16_+_81200697 1.93 ENSMUST00000067602.3
ENSMUST00000037785.7
neural cell adhesion molecule 2
chr17_+_36958623 1.91 ENSMUST00000173814.1
Znrd1 antisense
chr1_+_88103229 1.90 ENSMUST00000113135.3
ENSMUST00000113138.1
UDP glucuronosyltransferase 1 family, polypeptide A6A
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr4_+_100478806 1.89 ENSMUST00000133493.2
ENSMUST00000092730.3
ENSMUST00000106979.3
ubiquitin-conjugating enzyme E2U (putative)
chr4_+_97777606 1.86 ENSMUST00000075448.6
ENSMUST00000092532.6
nuclear factor I/A
chr14_+_61607455 1.85 ENSMUST00000051184.8
potassium channel regulator
chr17_+_24840108 1.84 ENSMUST00000164251.1
hydroxyacyl glutathione hydrolase
chr1_+_88138364 1.83 ENSMUST00000014263.4
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr9_+_110243783 1.82 ENSMUST00000035058.5
chondroitin sulfate proteoglycan 5
chr11_-_68386974 1.82 ENSMUST00000135141.1
netrin 1
chrX_+_101376359 1.81 ENSMUST00000119080.1
gap junction protein, beta 1
chr5_+_102481546 1.75 ENSMUST00000112854.1
Rho GTPase activating protein 24
chr17_+_70522083 1.72 ENSMUST00000148486.1
ENSMUST00000133717.1
discs, large (Drosophila) homolog-associated protein 1
chr15_+_25940846 1.72 ENSMUST00000110438.1
family with sequence similarity 134, member B
chr11_+_4883186 1.71 ENSMUST00000139737.1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr5_-_66054499 1.71 ENSMUST00000145625.1
RNA binding motif protein 47
chr17_-_31144271 1.64 ENSMUST00000024826.7
trefoil factor 2 (spasmolytic protein 1)
chr2_-_90479165 1.63 ENSMUST00000111495.2
protein tyrosine phosphatase, receptor type, J
chr2_+_27676440 1.62 ENSMUST00000129514.1
retinoid X receptor alpha
chr9_+_114731177 1.61 ENSMUST00000035007.8
CKLF-like MARVEL transmembrane domain containing 6
chr16_-_43664145 1.60 ENSMUST00000096065.4
T cell immunoreceptor with Ig and ITIM domains
chr6_-_142278836 1.59 ENSMUST00000111825.3
solute carrier organic anion transporter family, member 1a5
chr2_-_104742802 1.59 ENSMUST00000028595.7
DEP domain containing 7
chr4_+_102570065 1.58 ENSMUST00000097950.2
phosphodiesterase 4B, cAMP specific
chr13_-_29855630 1.58 ENSMUST00000091674.5
ENSMUST00000006353.7
CDK5 regulatory subunit associated protein 1-like 1
chr2_+_80617045 1.53 ENSMUST00000028384.4
dual specificity phosphatase 19
chr14_-_45477856 1.52 ENSMUST00000141424.1
fermitin family homolog 2 (Drosophila)
chr12_-_103863551 1.52 ENSMUST00000085056.6
ENSMUST00000072876.5
ENSMUST00000124717.1
serine (or cysteine) peptidase inhibitor, clade A, member 1A
chr9_-_71163224 1.51 ENSMUST00000074465.2
aquaporin 9
chr3_-_138131356 1.51 ENSMUST00000029805.8
microsomal triglyceride transfer protein
chr1_-_180245757 1.50 ENSMUST00000111104.1
presenilin 2
chr8_+_45628176 1.49 ENSMUST00000130850.1
sorbin and SH3 domain containing 2
chr8_-_79294928 1.48 ENSMUST00000048718.2
methylmalonic aciduria (cobalamin deficiency) type A
chr5_+_102481374 1.46 ENSMUST00000094559.2
ENSMUST00000073302.5
Rho GTPase activating protein 24
chr5_-_86906937 1.43 ENSMUST00000031181.9
ENSMUST00000113333.1
UDP glucuronosyltransferase 2 family, polypeptide B34
chrX_+_129749830 1.43 ENSMUST00000113320.2
diaphanous homolog 2 (Drosophila)
chr15_+_9071252 1.42 ENSMUST00000100789.4
ENSMUST00000100790.3
ENSMUST00000067760.4
NAD kinase 2, mitochondrial
chr15_-_3303521 1.42 ENSMUST00000165386.1
coiled-coil domain containing 152
chr12_+_104115970 1.40 ENSMUST00000021496.7
serine (or cysteine) peptidase inhibitor, clade A, member 3A
chr11_-_46389509 1.39 ENSMUST00000020664.6
IL2 inducible T cell kinase
chr15_+_3270767 1.36 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
selenoprotein P, plasma, 1
chr9_+_123806468 1.35 ENSMUST00000049810.7
chemokine (C-X-C motif) receptor 6
chr17_-_30612613 1.31 ENSMUST00000167624.1
ENSMUST00000024823.6
glyoxalase 1
chr19_+_44992127 1.29 ENSMUST00000179305.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr1_-_179546261 1.29 ENSMUST00000027769.5
transcription factor B2, mitochondrial
chr4_+_102430047 1.28 ENSMUST00000172616.1
phosphodiesterase 4B, cAMP specific
chr1_+_59482133 1.28 ENSMUST00000114246.2
ENSMUST00000037105.6
frizzled homolog 7 (Drosophila)
chr6_-_83656082 1.27 ENSMUST00000014686.2
C-type lectin domain family 4, member f
chrM_+_9870 1.26 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr12_-_108275409 1.25 ENSMUST00000136175.1
coiled-coil domain containing 85C
chr6_-_136875794 1.25 ENSMUST00000032342.1
matrix Gla protein
chr11_-_54860564 1.23 ENSMUST00000144164.1
LYR motif containing 7
chr6_+_115422040 1.22 ENSMUST00000000450.3
peroxisome proliferator activated receptor gamma
chr9_-_44802951 1.22 ENSMUST00000044694.6
tetratricopeptide repeat domain 36
chr8_-_25785154 1.21 ENSMUST00000038498.8
BCL2-associated athanogene 4
chr14_-_45388772 1.20 ENSMUST00000046191.7
glucosamine-phosphate N-acetyltransferase 1
chr19_-_6909599 1.19 ENSMUST00000173091.1
peroxiredoxin 5
chr6_+_39592569 1.18 ENSMUST00000135671.1
ENSMUST00000119379.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr3_-_63929376 1.18 ENSMUST00000061706.6
RIKEN cDNA E130311K13 gene
chr15_-_5108492 1.18 ENSMUST00000118365.2
caspase recruitment domain family, member 6
chrM_+_2743 1.16 ENSMUST00000082392.1
mitochondrially encoded NADH dehydrogenase 1
chr13_+_40859768 1.16 ENSMUST00000110191.2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr5_-_92215345 1.15 ENSMUST00000031356.4
cDNA sequence U90926
chr6_-_98342728 1.14 ENSMUST00000164491.1
predicted gene 765
chr1_-_24612700 1.13 ENSMUST00000088336.1
predicted gene 10222
chr2_-_148046896 1.13 ENSMUST00000172928.1
ENSMUST00000047315.3
forkhead box A2
chr12_+_104214538 1.13 ENSMUST00000121337.1
ENSMUST00000167049.1
ENSMUST00000101080.1
serine (or cysteine) peptidase inhibitor, clade A, member 3F
chr11_-_46389471 1.13 ENSMUST00000109237.2
IL2 inducible T cell kinase
chr1_+_172698046 1.13 ENSMUST00000038495.3
C-reactive protein, pentraxin-related
chr6_-_142011414 1.10 ENSMUST00000181628.1
ENSMUST00000181791.1
predicted gene 6614
chr3_+_85915722 1.07 ENSMUST00000054148.7
predicted gene 9790
chr11_-_31824518 1.06 ENSMUST00000134944.1
RIKEN cDNA D630024D03 gene
chr14_+_46832127 1.06 ENSMUST00000068532.8
cell growth regulator with ring finger domain 1
chr1_-_171150588 1.06 ENSMUST00000155798.1
ENSMUST00000081560.4
ENSMUST00000111336.3
succinate dehydrogenase complex, subunit C, integral membrane protein
chrM_+_10167 1.06 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr11_-_46389454 1.06 ENSMUST00000101306.3
IL2 inducible T cell kinase
chr2_-_51973219 1.05 ENSMUST00000028314.2
N-myc (and STAT) interactor
chr1_+_171225054 1.04 ENSMUST00000111321.1
ENSMUST00000005824.5
ENSMUST00000111320.1
ENSMUST00000111319.1
apolipoprotein A-II
chr13_+_23531044 1.03 ENSMUST00000102972.3
histone cluster 1, H4h
chr12_-_70231414 1.02 ENSMUST00000161083.1
liver glycogen phosphorylase
chr10_-_128923948 1.02 ENSMUST00000131271.1
biogenesis of lysosome-related organelles complex-1, subunit 1
chr14_+_52821860 1.01 ENSMUST00000181793.1
ENSMUST00000184436.1
T cell receptor alpha variable 6D-6
chr11_-_99620432 1.01 ENSMUST00000073853.2
predicted gene 11562
chr19_+_11747548 0.99 ENSMUST00000025585.3
gastric intrinsic factor
chr3_+_107230608 0.97 ENSMUST00000179399.1
RIKEN cDNA A630076J17 gene
chr9_+_122888471 0.96 ENSMUST00000063980.6
zinc finger with KRAB and SCAN domains 7
chr12_+_118846329 0.94 ENSMUST00000063918.2
trans-acting transcription factor 8
chr6_-_87851011 0.93 ENSMUST00000113617.1
cellular nucleic acid binding protein
chr2_-_110305730 0.93 ENSMUST00000046233.2
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr15_+_4375462 0.92 ENSMUST00000061925.4
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr2_-_101621033 0.90 ENSMUST00000090513.4
RIKEN cDNA B230118H07 gene
chr19_-_6910088 0.89 ENSMUST00000025904.5
peroxiredoxin 5
chr15_-_5108469 0.89 ENSMUST00000141020.1
caspase recruitment domain family, member 6
chr9_-_62070606 0.88 ENSMUST00000034785.7
glucuronyl C5-epimerase
chr9_+_7571396 0.88 ENSMUST00000120900.1
ENSMUST00000093896.3
ENSMUST00000151853.1
ENSMUST00000152878.1
matrix metallopeptidase 27
chr13_-_110280103 0.88 ENSMUST00000167824.1
RAB3C, member RAS oncogene family
chr17_-_42692244 0.87 ENSMUST00000170723.1
ENSMUST00000164524.1
ENSMUST00000024711.4
ENSMUST00000167993.1
G protein-coupled receptor 115
chr13_-_92483996 0.86 ENSMUST00000040106.7
family with sequence similarity 151, member B
chr19_+_55253369 0.84 ENSMUST00000043150.4
acyl-CoA synthetase long-chain family member 5
chr2_-_51972990 0.84 ENSMUST00000145481.1
ENSMUST00000112705.2
N-myc (and STAT) interactor
chr19_+_43782181 0.83 ENSMUST00000026208.4
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr2_-_134554348 0.82 ENSMUST00000028704.2
hydroxyacid oxidase 1, liver
chr16_-_85550417 0.82 ENSMUST00000175700.1
ENSMUST00000114174.2
cysteine and tyrosine-rich protein 1
chr7_-_65371210 0.81 ENSMUST00000102592.3
tight junction protein 1
chr11_-_60036917 0.81 ENSMUST00000102692.3
phosphatidylethanolamine N-methyltransferase
chr4_-_25281752 0.81 ENSMUST00000038705.7
UFM1 specific ligase 1
chr4_-_45532470 0.81 ENSMUST00000147448.1
src homology 2 domain-containing transforming protein B
chr14_-_48662740 0.81 ENSMUST00000122009.1
orthodenticle homolog 2 (Drosophila)
chr8_-_121083085 0.79 ENSMUST00000182264.1
Foxf1 adjacent non-coding developmental regulatory RNA
chr2_-_63184170 0.78 ENSMUST00000112452.1
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr3_+_121531603 0.77 ENSMUST00000180804.1
RIKEN cDNA A530020G20 gene
chrX_-_108664891 0.77 ENSMUST00000178160.1
predicted gene 379
chr11_+_98446826 0.77 ENSMUST00000019456.4
growth factor receptor bound protein 7
chr4_-_84546284 0.75 ENSMUST00000177040.1
basonuclin 2
chr16_-_95459245 0.74 ENSMUST00000176345.1
ENSMUST00000121809.2
ENSMUST00000118113.1
ENSMUST00000122199.1
avian erythroblastosis virus E-26 (v-ets) oncogene related
chr16_-_88563166 0.72 ENSMUST00000049697.4
claudin 8
chr19_-_20954202 0.71 ENSMUST00000039500.3
transmembrane channel-like gene family 1
chr18_+_33464163 0.71 ENSMUST00000097634.3
predicted gene 10549
chrX_+_7579666 0.69 ENSMUST00000115740.1
ENSMUST00000115739.1
forkhead box P3
chrY_-_10643315 0.69 ENSMUST00000100115.1
predicted gene, 20775
chr13_-_83729544 0.68 ENSMUST00000181705.1
predicted gene, 26803
chr4_+_105157339 0.68 ENSMUST00000064139.7
phosphatidic acid phosphatase type 2B
chr19_-_38125258 0.68 ENSMUST00000025951.6
retinol binding protein 4, plasma
chr10_+_52391606 0.67 ENSMUST00000067085.4
nephrocan
chr9_-_48835932 0.67 ENSMUST00000093852.3
zinc finger and BTB domain containing 16
chr19_-_19111181 0.66 ENSMUST00000112832.1
RAR-related orphan receptor beta
chr2_+_164833781 0.66 ENSMUST00000143780.1
cathepsin A
chr2_-_63184253 0.66 ENSMUST00000075052.3
ENSMUST00000112454.1
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr17_+_70522149 0.66 ENSMUST00000140728.1
discs, large (Drosophila) homolog-associated protein 1
chr10_-_130280218 0.65 ENSMUST00000061571.3
neurogenic differentiation 4
chr9_+_62342449 0.65 ENSMUST00000156461.1
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr10_+_127421208 0.65 ENSMUST00000168780.1
R3H domain containing 2
chr10_-_61979073 0.64 ENSMUST00000105453.1
ENSMUST00000105452.2
ENSMUST00000105454.2
collagen, type XIII, alpha 1
chr6_-_128581597 0.63 ENSMUST00000060574.7
cDNA sequence BC048546
chr6_-_143947061 0.63 ENSMUST00000124233.1
SRY-box containing gene 5
chr5_-_62765618 0.63 ENSMUST00000159470.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 18.3 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
2.1 8.4 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
1.5 13.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.2 5.8 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.7 2.1 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.6 1.9 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.6 2.4 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.5 2.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.5 6.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.4 1.2 GO:0072343 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.4 2.0 GO:1904253 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.4 2.7 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.4 15.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.4 1.5 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.4 1.1 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.4 3.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.4 2.5 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.3 1.0 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.3 1.6 GO:0045994 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.3 1.3 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.3 3.2 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.3 3.7 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.3 3.1 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.3 1.2 GO:0090365 regulation of mRNA modification(GO:0090365)
0.3 0.9 GO:0030210 heparin biosynthetic process(GO:0030210)
0.3 1.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.3 1.0 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.3 7.1 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.2 4.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 2.6 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.2 1.2 GO:0006041 glucosamine metabolic process(GO:0006041) UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.2 1.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 1.6 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.2 0.9 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 0.7 GO:0002458 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment(GO:0002362) peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465) negative regulation of histone deacetylation(GO:0031064) negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.2 1.8 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 5.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 2.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 1.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.8 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 1.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.2 0.8 GO:1990401 embryonic lung development(GO:1990401)
0.2 3.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 1.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.2 2.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 2.4 GO:0070842 aggresome assembly(GO:0070842)
0.2 0.7 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.2 1.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 1.8 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.2 1.0 GO:0015889 cobalamin transport(GO:0015889)
0.2 0.8 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.2 0.9 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.2 1.4 GO:0090166 Golgi disassembly(GO:0090166)
0.1 0.6 GO:0032468 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 1.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.4 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 1.6 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.8 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.1 1.7 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 2.3 GO:0015874 organic cation transport(GO:0015695) norepinephrine transport(GO:0015874)
0.1 0.8 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.8 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 2.8 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.9 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 2.4 GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901028)
0.1 6.7 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 3.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 1.5 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.4 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 0.7 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 1.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 5.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.3 GO:0001777 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.6 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.1 0.4 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.4 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 1.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 1.3 GO:0051132 NK T cell activation(GO:0051132)
0.1 0.6 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.1 1.9 GO:0072189 ureter development(GO:0072189)
0.1 0.4 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.4 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.9 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 1.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.8 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.2 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.4 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.1 0.8 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.1 0.3 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830)
0.1 1.6 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.1 1.5 GO:0033622 integrin activation(GO:0033622)
0.1 0.4 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.1 0.2 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.1 0.3 GO:0009405 pathogenesis(GO:0009405)
0.1 0.3 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 1.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 5.2 GO:0048663 neuron fate commitment(GO:0048663)
0.1 0.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 1.0 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 1.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.4 GO:0030035 microspike assembly(GO:0030035)
0.0 0.4 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) embryonic genitalia morphogenesis(GO:0030538) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 1.0 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 1.2 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 1.7 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.4 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 5.6 GO:0009166 nucleotide catabolic process(GO:0009166)
0.0 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 1.3 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.2 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 4.5 GO:0051028 mRNA transport(GO:0051028)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.4 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.8 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.8 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.6 GO:0014823 response to activity(GO:0014823)
0.0 1.9 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.4 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.5 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 4.7 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.3 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.4 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.0 0.8 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.8 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 2.9 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 4.4 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.4 GO:0042572 retinol metabolic process(GO:0042572)
0.0 1.2 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.4 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.8 GO:0006400 tRNA modification(GO:0006400)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 25.1 GO:0005579 membrane attack complex(GO:0005579)
0.7 5.3 GO:0045098 type III intermediate filament(GO:0045098)
0.5 2.4 GO:0044316 cone cell pedicle(GO:0044316)
0.3 1.9 GO:0033503 HULC complex(GO:0033503)
0.3 1.1 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 2.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 2.7 GO:0071437 invadopodium(GO:0071437)
0.2 1.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.9 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 2.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.2 GO:0000421 autophagosome membrane(GO:0000421)
0.1 4.2 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.9 GO:0005922 connexon complex(GO:0005922)
0.1 3.0 GO:0005581 collagen trimer(GO:0005581)
0.1 2.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 3.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.5 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.0 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 1.0 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 21.5 GO:0000139 Golgi membrane(GO:0000139)
0.1 0.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.4 GO:0097444 spine apparatus(GO:0097444)
0.1 6.2 GO:0031526 brush border membrane(GO:0031526)
0.1 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 9.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.6 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.6 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 1.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 2.9 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.1 GO:0070469 respiratory chain(GO:0070469)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.5 GO:0031941 filamentous actin(GO:0031941)
0.0 1.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 6.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 2.2 GO:0005604 basement membrane(GO:0005604)
0.0 1.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.9 GO:0001772 immunological synapse(GO:0001772)
0.0 3.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 6.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.6 GO:0030175 filopodium(GO:0030175)
0.0 3.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 4.9 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 3.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 4.7 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.8 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
3.3 13.3 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
1.1 5.3 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.8 2.5 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.7 4.9 GO:0005534 galactose binding(GO:0005534)
0.7 2.1 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.6 4.8 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.5 1.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.4 6.0 GO:0044548 S100 protein binding(GO:0044548)
0.3 1.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3 1.5 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.3 1.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3 0.8 GO:0071568 UFM1 transferase activity(GO:0071568)
0.3 2.2 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.3 1.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.3 1.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.3 1.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.2 1.4 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.2 0.8 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.2 1.8 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 2.6 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.2 1.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.2 1.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 0.9 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 2.9 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.6 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 0.4 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.1 1.1 GO:0001849 complement component C1q binding(GO:0001849)
0.1 2.2 GO:0030957 Tat protein binding(GO:0030957)
0.1 1.6 GO:0070097 delta-catenin binding(GO:0070097)
0.1 5.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 17.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 4.0 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.1 5.3 GO:0030552 cAMP binding(GO:0030552)
0.1 1.8 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 1.2 GO:0050693 LBD domain binding(GO:0050693)
0.1 1.0 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.7 GO:0071253 connexin binding(GO:0071253)
0.1 0.4 GO:0051373 FATZ binding(GO:0051373)
0.1 0.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.2 GO:0016015 morphogen activity(GO:0016015)
0.1 0.3 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 0.9 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.4 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 1.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.3 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.7 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 3.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.9 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 1.7 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 2.0 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 1.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 3.8 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 5.1 GO:0005178 integrin binding(GO:0005178)
0.0 2.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 1.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 1.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 3.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 1.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.9 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 3.9 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 3.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.2 GO:0051087 chaperone binding(GO:0051087)
0.0 0.6 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.2 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 6.0 PID FGF PATHWAY FGF signaling pathway
0.1 3.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 1.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 3.8 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 2.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.8 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 6.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 7.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.8 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 29.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.8 10.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.4 6.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.3 5.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.2 2.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.2 1.8 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 3.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 7.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.5 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 3.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 7.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 1.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 13.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.6 REACTOME SIGNALLING BY NGF Genes involved in Signalling by NGF
0.0 1.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.0 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 4.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.7 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.7 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.6 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization