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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Foxf2

Z-value: 1.66

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Transcription factors associated with Foxf2

Gene Symbol Gene ID Gene Info
Foxf2
ENSMUSG00000038402.2 forkhead box F2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxf2mm10_v2_chr13_+_31625802_316258160.391.8e-02Click!

Activity profile of Foxf2 motif

Sorted Z-values of Foxf2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_106167564 11.06 ENSMUST00000063062.8
Chi3l3
chitinase 3-like 3
chr8_+_70373541 8.39 ENSMUST00000003659.7
Comp
cartilage oligomeric matrix protein
chr8_-_85380964 8.38 ENSMUST00000122452.1
Mylk3
myosin light chain kinase 3
chr4_-_87806296 7.48 ENSMUST00000126353.1
ENSMUST00000149357.1
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr4_-_87806276 5.67 ENSMUST00000148059.1
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr2_-_84822546 5.50 ENSMUST00000028471.5
Smtnl1
smoothelin-like 1
chr10_+_88091070 5.22 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr13_-_23465872 5.22 ENSMUST00000041674.7
Btn1a1
butyrophilin, subfamily 1, member A1
chr10_+_115817247 5.18 ENSMUST00000035563.7
ENSMUST00000080630.3
ENSMUST00000179196.1
Tspan8
tetraspanin 8
chr15_+_79348061 4.41 ENSMUST00000163691.1
Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr2_-_118728345 4.40 ENSMUST00000159756.1
Plcb2
phospholipase C, beta 2
chr2_-_126500631 4.31 ENSMUST00000129187.1
Atp8b4
ATPase, class I, type 8B, member 4
chr17_+_47505117 4.12 ENSMUST00000183044.1
ENSMUST00000037333.10
Ccnd3
cyclin D3
chr15_+_79347534 3.99 ENSMUST00000096350.3
Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr17_+_47505149 3.96 ENSMUST00000183177.1
ENSMUST00000182848.1
Ccnd3
cyclin D3
chr2_-_118728430 3.83 ENSMUST00000102524.1
Plcb2
phospholipase C, beta 2
chr2_-_170406501 3.77 ENSMUST00000154650.1
Bcas1
breast carcinoma amplified sequence 1
chr17_+_47505211 3.71 ENSMUST00000182935.1
ENSMUST00000182506.1
Ccnd3
cyclin D3
chr9_-_58741543 3.65 ENSMUST00000098674.4
2410076I21Rik
RIKEN cDNA 2410076I21 gene
chr13_-_23465895 3.63 ENSMUST00000110434.1
Btn1a1
butyrophilin, subfamily 1, member A1
chr15_-_66969616 3.41 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
Ndrg1
N-myc downstream regulated gene 1
chr8_+_86745679 2.92 ENSMUST00000098532.2
Gm10638
predicted gene 10638
chr10_+_37139558 2.83 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr12_-_111980751 2.79 ENSMUST00000170525.1
BC048943
cDNA sequence BC048943
chr14_+_55854115 2.71 ENSMUST00000168479.1
Nynrin
NYN domain and retroviral integrase containing
chr7_-_98145472 2.49 ENSMUST00000098281.2
Omp
olfactory marker protein
chr2_-_163645125 2.44 ENSMUST00000017851.3
Serinc3
serine incorporator 3
chr5_+_118560719 2.42 ENSMUST00000100816.4
Med13l
mediator complex subunit 13-like
chr2_-_126499839 2.42 ENSMUST00000040128.5
Atp8b4
ATPase, class I, type 8B, member 4
chr15_-_58324161 2.39 ENSMUST00000022985.1
Klhl38
kelch-like 38
chr8_+_93810832 2.35 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1
guanine nucleotide binding protein, alpha O
chrX_+_163911401 2.32 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr7_+_30291659 2.30 ENSMUST00000014065.8
ENSMUST00000150892.1
ENSMUST00000126216.1
Clip3
CAP-GLY domain containing linker protein 3
chr14_+_55853997 2.30 ENSMUST00000100529.3
Nynrin
NYN domain and retroviral integrase containing
chr4_+_101507947 2.15 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr19_+_53329413 1.98 ENSMUST00000025998.7
Mxi1
Max interacting protein 1
chr18_-_88927447 1.93 ENSMUST00000147313.1
Socs6
suppressor of cytokine signaling 6
chr5_-_115098295 1.87 ENSMUST00000100848.2
Gm10401
predicted gene 10401
chr7_+_30291941 1.85 ENSMUST00000144508.1
Clip3
CAP-GLY domain containing linker protein 3
chr16_-_29946499 1.85 ENSMUST00000181968.1
Gm26569
predicted gene, 26569
chr11_+_69095217 1.84 ENSMUST00000101004.2
Per1
period circadian clock 1
chr15_-_50882806 1.75 ENSMUST00000184885.1
Trps1
trichorhinophalangeal syndrome I (human)
chr3_-_27896360 1.74 ENSMUST00000058077.3
Tmem212
transmembrane protein 212
chr10_-_37138863 1.74 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr5_+_86071734 1.71 ENSMUST00000031171.7
Stap1
signal transducing adaptor family member 1
chr3_-_93015669 1.68 ENSMUST00000107301.1
ENSMUST00000029521.4
Crct1
cysteine-rich C-terminal 1
chr9_+_70678950 1.66 ENSMUST00000067880.6
Adam10
a disintegrin and metallopeptidase domain 10
chr1_+_43445736 1.56 ENSMUST00000086421.5
ENSMUST00000114744.1
Nck2
non-catalytic region of tyrosine kinase adaptor protein 2
chr13_+_44840686 1.54 ENSMUST00000173906.1
Jarid2
jumonji, AT rich interactive domain 2
chr7_-_142372210 1.54 ENSMUST00000084412.5
Ifitm10
interferon induced transmembrane protein 10
chr13_-_95478655 1.49 ENSMUST00000022186.3
S100z
S100 calcium binding protein, zeta
chr19_+_23723279 1.45 ENSMUST00000067077.1
Gm9938
predicted gene 9938
chr2_-_168601620 1.43 ENSMUST00000171689.1
ENSMUST00000137451.1
Nfatc2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
chr12_+_69296676 1.39 ENSMUST00000021362.4
Klhdc2
kelch domain containing 2
chr19_+_45149833 1.34 ENSMUST00000026236.9
Tlx1
T cell leukemia, homeobox 1
chr4_+_101507855 1.26 ENSMUST00000038207.5
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr2_+_26973416 1.24 ENSMUST00000014996.7
ENSMUST00000102891.3
Adamts13
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13
chr12_+_3807076 1.23 ENSMUST00000174817.1
Dnmt3a
DNA methyltransferase 3A
chr17_+_29090969 1.20 ENSMUST00000119901.1
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr13_+_55445301 1.17 ENSMUST00000001115.8
ENSMUST00000099482.3
Grk6
G protein-coupled receptor kinase 6
chrX_-_10216918 1.15 ENSMUST00000072393.2
ENSMUST00000044598.6
ENSMUST00000073392.4
ENSMUST00000115533.1
ENSMUST00000115532.1
Rpgr
retinitis pigmentosa GTPase regulator
chr3_+_53488677 1.15 ENSMUST00000029307.3
Stoml3
stomatin (Epb7.2)-like 3
chr4_+_5724304 1.13 ENSMUST00000108380.1
Fam110b
family with sequence similarity 110, member B
chr1_+_179546303 1.11 ENSMUST00000040706.8
Cnst
consortin, connexin sorting protein
chr12_+_3807017 1.09 ENSMUST00000020991.8
ENSMUST00000172509.1
Dnmt3a
DNA methyltransferase 3A
chr4_+_155791172 1.05 ENSMUST00000105593.1
Ankrd65
ankyrin repeat domain 65
chr2_+_112265809 1.00 ENSMUST00000110991.2
Slc12a6
solute carrier family 12, member 6
chr18_-_47333311 0.96 ENSMUST00000126684.1
ENSMUST00000156422.1
Sema6a
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr12_-_15816762 0.95 ENSMUST00000020922.7
Trib2
tribbles homolog 2 (Drosophila)
chr7_-_30559828 0.92 ENSMUST00000108164.1
Lin37
lin-37 homolog (C. elegans)
chr14_+_26514554 0.92 ENSMUST00000104927.1
Gm2178
predicted gene 2178
chr6_+_147032528 0.91 ENSMUST00000036194.4
Rep15
RAB15 effector protein
chr4_-_55532453 0.90 ENSMUST00000132746.1
ENSMUST00000107619.2
Klf4
Kruppel-like factor 4 (gut)
chr5_+_62813823 0.90 ENSMUST00000170704.1
Gm17384
predicted gene, 17384
chr18_-_65393844 0.89 ENSMUST00000035548.8
Alpk2
alpha-kinase 2
chr11_-_54956047 0.87 ENSMUST00000155316.1
ENSMUST00000108889.3
ENSMUST00000126703.1
Tnip1
TNFAIP3 interacting protein 1
chr5_-_6876523 0.85 ENSMUST00000164784.1
Zfp804b
zinc finger protein 804B
chr4_-_82885148 0.81 ENSMUST00000048430.3
Cer1
cerberus 1 homolog (Xenopus laevis)
chr15_-_79441802 0.80 ENSMUST00000122044.1
ENSMUST00000135519.1
Csnk1e
casein kinase 1, epsilon
chr16_-_4880284 0.77 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr10_+_25408346 0.77 ENSMUST00000092645.6
Epb4.1l2
erythrocyte protein band 4.1-like 2
chr2_-_73312701 0.76 ENSMUST00000058615.9
Cir1
corepressor interacting with RBPJ, 1
chr15_+_54410755 0.76 ENSMUST00000036737.3
Colec10
collectin sub-family member 10
chr13_+_22087878 0.76 ENSMUST00000091739.1
Vmn1r188
vomeronasal 1 receptor 188
chr1_-_39720989 0.74 ENSMUST00000151913.1
Rfx8
regulatory factor X 8
chr6_-_57844493 0.72 ENSMUST00000081186.3
Vmn1r21
vomeronasal 1 receptor 21
chr8_-_125492710 0.70 ENSMUST00000108775.1
Sipa1l2
signal-induced proliferation-associated 1 like 2
chr3_-_37232565 0.70 ENSMUST00000161015.1
ENSMUST00000029273.1
Il21
interleukin 21
chr2_-_181578906 0.67 ENSMUST00000136875.1
Uckl1
uridine-cytidine kinase 1-like 1
chr10_+_40349265 0.67 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19
cyclin-dependent kinase 19
chr15_-_66560997 0.66 ENSMUST00000048372.5
Tmem71
transmembrane protein 71
chr15_-_79441999 0.66 ENSMUST00000117786.1
ENSMUST00000120859.1
Csnk1e
casein kinase 1, epsilon
chr14_+_58072686 0.65 ENSMUST00000022545.7
Fgf9
fibroblast growth factor 9
chr7_-_44849075 0.63 ENSMUST00000047085.8
Tbc1d17
TBC1 domain family, member 17
chr11_-_120990871 0.62 ENSMUST00000154483.1
Csnk1d
casein kinase 1, delta
chr5_+_107437908 0.62 ENSMUST00000094541.2
Btbd8
BTB (POZ) domain containing 8
chr19_-_45783512 0.59 ENSMUST00000026243.3
Mgea5
meningioma expressed antigen 5 (hyaluronidase)
chr10_+_126978690 0.58 ENSMUST00000105256.2
Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr12_-_112511136 0.57 ENSMUST00000066791.5
Tmem179
transmembrane protein 179
chr2_-_60125651 0.57 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr9_-_108649349 0.56 ENSMUST00000013338.8
Arih2
ariadne homolog 2 (Drosophila)
chr7_+_90426312 0.53 ENSMUST00000061391.7
Ccdc89
coiled-coil domain containing 89
chr15_+_91838322 0.53 ENSMUST00000160242.1
ENSMUST00000109276.1
ENSMUST00000088555.3
ENSMUST00000100293.2
ENSMUST00000126508.1
Muc19
Smgc
mucin 19
submandibular gland protein C
chr18_+_55057557 0.51 ENSMUST00000181765.1
Gm4221
predicted gene 4221
chr1_+_51289106 0.49 ENSMUST00000051572.6
Sdpr
serum deprivation response
chr1_+_40681659 0.45 ENSMUST00000027231.7
Slc9a2
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr2_-_71367749 0.43 ENSMUST00000151937.1
Slc25a12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr12_+_71016658 0.40 ENSMUST00000125125.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr7_+_44849216 0.37 ENSMUST00000054343.8
Akt1s1
AKT1 substrate 1 (proline-rich)
chr10_-_49783259 0.35 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
Grik2
glutamate receptor, ionotropic, kainate 2 (beta 2)
chr7_+_82175156 0.31 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr18_+_34759551 0.30 ENSMUST00000097622.3
Fam53c
family with sequence similarity 53, member C
chr3_+_65528457 0.29 ENSMUST00000130705.1
Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
chr16_-_79091078 0.27 ENSMUST00000023566.4
ENSMUST00000060402.5
Tmprss15
transmembrane protease, serine 15
chr1_+_34005872 0.27 ENSMUST00000182296.1
Dst
dystonin
chr6_+_34863130 0.25 ENSMUST00000074949.3
Tmem140
transmembrane protein 140
chr3_+_65528404 0.23 ENSMUST00000047906.3
Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
chr11_+_85311232 0.19 ENSMUST00000020835.9
Ppm1d
protein phosphatase 1D magnesium-dependent, delta isoform
chr16_-_22439719 0.18 ENSMUST00000079601.6
Etv5
ets variant gene 5
chr16_-_22439570 0.17 ENSMUST00000170393.1
Etv5
ets variant gene 5
chr5_-_103211251 0.13 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
Mapk10
mitogen-activated protein kinase 10
chrX_-_79434418 0.10 ENSMUST00000179788.1
Chdc2
calponin homology domain containing 2
chr5_+_87925579 0.09 ENSMUST00000001667.6
ENSMUST00000113267.1
Csn3
casein kappa
chr4_-_118409219 0.06 ENSMUST00000075406.5
Szt2
seizure threshold 2
chr7_+_44848991 0.05 ENSMUST00000107885.1
Akt1s1
AKT1 substrate 1 (proline-rich)
chr9_+_44072196 0.05 ENSMUST00000176671.1
Usp2
ubiquitin specific peptidase 2
chr10_-_26373956 0.04 ENSMUST00000105519.3
ENSMUST00000040219.6
L3mbtl3
l(3)mbt-like 3 (Drosophila)
chr8_-_18741542 0.03 ENSMUST00000033846.6
Angpt2
angiopoietin 2
chr3_+_51693771 0.01 ENSMUST00000099104.2
Gm10729
predicted gene 10729
chr7_-_4844665 0.00 ENSMUST00000066041.5
ENSMUST00000172377.1
Shisa7
shisa homolog 7 (Xenopus laevis)

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxf2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
1.4 8.4 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.8 13.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.6 8.8 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.6 5.0 GO:0015074 DNA integration(GO:0015074)
0.6 4.2 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.6 1.7 GO:1903972 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.6 3.4 GO:0072318 clathrin coat disassembly(GO:0072318)
0.5 11.8 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.5 4.0 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.4 8.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.4 1.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.4 1.8 GO:0097167 circadian regulation of translation(GO:0097167)
0.4 9.2 GO:0003417 growth plate cartilage development(GO:0003417)
0.3 1.7 GO:0042117 monocyte activation(GO:0042117)
0.3 0.9 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.3 3.4 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.3 0.9 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.3 1.2 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.3 2.3 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.2 0.7 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 0.7 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.2 2.1 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.2 5.5 GO:0014823 response to activity(GO:0014823)
0.1 1.2 GO:0071493 cellular response to UV-B(GO:0071493)
0.1 8.4 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.7 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.1 0.6 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616)
0.1 1.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.9 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 0.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 1.8 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 0.4 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1 0.9 GO:0033572 transferrin transport(GO:0033572)
0.1 0.4 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 1.7 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 2.3 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 6.7 GO:0007030 Golgi organization(GO:0007030)
0.0 1.3 GO:0048535 lymph node development(GO:0048535)
0.0 0.5 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 2.3 GO:0060612 adipose tissue development(GO:0060612)
0.0 1.3 GO:0019236 response to pheromone(GO:0019236)
0.0 1.0 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.6 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.0 0.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 1.2 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 1.1 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.4 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 1.9 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.5 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 2.5 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.6 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.6 GO:0070534 protein K63-linked ubiquitination(GO:0070534)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 8.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.6 1.7 GO:0042585 germinal vesicle(GO:0042585)
0.4 1.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.3 11.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 13.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.2 7.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 1.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 5.5 GO:0031430 M band(GO:0031430)
0.1 0.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 2.3 GO:0001741 XY body(GO:0001741)
0.1 0.4 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 2.3 GO:0016592 mediator complex(GO:0016592)
0.1 1.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0031673 H zone(GO:0031673)
0.0 2.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 2.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 3.4 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 1.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.6 GO:0005876 spindle microtubule(GO:0005876)
0.0 3.7 GO:0014069 postsynaptic density(GO:0014069)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 8.4 GO:0005499 vitamin D binding(GO:0005499)
1.2 8.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.7 4.2 GO:0097001 ceramide binding(GO:0097001)
0.6 1.7 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.4 1.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.4 8.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.3 2.3 GO:0051430 G-protein coupled serotonin receptor binding(GO:0031821) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.3 1.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.3 2.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.3 5.5 GO:0005523 tropomyosin binding(GO:0005523)
0.3 0.8 GO:0016015 morphogen activity(GO:0016015)
0.3 12.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 0.7 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.2 6.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 5.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 0.9 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.2 2.4 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.7 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.1 GO:0071253 connexin binding(GO:0071253)
0.1 3.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.9 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 1.3 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 1.5 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.8 GO:0070888 E-box binding(GO:0070888)
0.0 1.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.8 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 2.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 2.3 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 2.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 1.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.0 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 11.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 3.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 0.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.6 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 8.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.6 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 3.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.2 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 10.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 13.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 2.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 1.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 3.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 6.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 8.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 3.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 3.9 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.1 2.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 4.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)