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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Gcm1

Z-value: 1.20

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Transcription factors associated with Gcm1

Gene Symbol Gene ID Gene Info
Gcm1
ENSMUSG00000023333.7 glial cells missing homolog 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gcm1mm10_v2_chr9_+_78051938_78051958-0.289.8e-02Click!

Activity profile of Gcm1 motif

Sorted Z-values of Gcm1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_30373358 7.41 ENSMUST00000021004.7
Sntg2
syntrophin, gamma 2
chr15_+_10249560 6.29 ENSMUST00000134410.1
Prlr
prolactin receptor
chr13_-_4523322 5.74 ENSMUST00000080361.5
ENSMUST00000078239.3
Akr1c20
aldo-keto reductase family 1, member C20
chr7_+_119900099 4.50 ENSMUST00000106516.1
Lyrm1
LYR motif containing 1
chr3_+_138217814 4.34 ENSMUST00000090171.5
Adh7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr8_-_45358737 3.85 ENSMUST00000155230.1
ENSMUST00000135912.1
Fam149a
family with sequence similarity 149, member A
chr6_-_124636085 3.08 ENSMUST00000068797.2
Gm5077
predicted gene 5077
chr11_-_106613370 2.95 ENSMUST00000128933.1
Tex2
testis expressed gene 2
chr17_-_32189457 2.90 ENSMUST00000087721.3
ENSMUST00000162117.1
Ephx3
epoxide hydrolase 3
chr8_-_3720640 2.65 ENSMUST00000062037.6
Clec4g
C-type lectin domain family 4, member g
chr16_+_38902305 2.57 ENSMUST00000023478.7
Igsf11
immunoglobulin superfamily, member 11
chr7_-_105600103 2.04 ENSMUST00000033185.8
Hpx
hemopexin
chr3_+_107230608 2.01 ENSMUST00000179399.1
A630076J17Rik
RIKEN cDNA A630076J17 gene
chr7_-_99182681 1.95 ENSMUST00000033001.4
Dgat2
diacylglycerol O-acyltransferase 2
chr3_+_89459325 1.94 ENSMUST00000107410.1
Pmvk
phosphomevalonate kinase
chr4_-_42661893 1.82 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr11_+_120491840 1.68 ENSMUST00000026899.3
Slc25a10
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
chr17_-_6948283 1.67 ENSMUST00000024572.9
Rsph3b
radial spoke 3B homolog (Chlamydomonas)
chr5_+_102724971 1.65 ENSMUST00000112853.1
Arhgap24
Rho GTPase activating protein 24
chr7_+_131966446 1.51 ENSMUST00000045840.4
Gpr26
G protein-coupled receptor 26
chr19_+_46761578 1.49 ENSMUST00000077666.4
ENSMUST00000099373.4
Cnnm2
cyclin M2
chr2_+_96318014 1.47 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c
leucine rich repeat containing 4C
chr2_-_35061431 1.44 ENSMUST00000028233.3
Hc
hemolytic complement
chr2_-_155834845 1.33 ENSMUST00000029143.5
Fam83c
family with sequence similarity 83, member C
chr7_-_68264201 1.32 ENSMUST00000032770.2
Pgpep1l
pyroglutamyl-peptidase I-like
chr11_-_121354337 1.26 ENSMUST00000106110.3
ENSMUST00000136797.1
ENSMUST00000026173.6
Wdr45b
WD repeat domain 45B
chr7_-_101011976 1.25 ENSMUST00000178340.1
ENSMUST00000037540.3
P2ry2
purinergic receptor P2Y, G-protein coupled 2
chr2_+_169633517 1.25 ENSMUST00000109157.1
Tshz2
teashirt zinc finger family member 2
chr11_-_35980473 1.21 ENSMUST00000018993.6
Wwc1
WW, C2 and coiled-coil domain containing 1
chr14_-_66213552 1.19 ENSMUST00000178730.1
Ptk2b
PTK2 protein tyrosine kinase 2 beta
chr1_+_174050375 1.14 ENSMUST00000062665.3
Olfr432
olfactory receptor 432
chr17_-_24696147 1.12 ENSMUST00000046839.8
Gfer
growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration)
chr7_+_44997648 1.11 ENSMUST00000003284.8
ENSMUST00000107835.1
Irf3
interferon regulatory factor 3
chr11_-_60352869 1.09 ENSMUST00000095254.5
ENSMUST00000102683.4
ENSMUST00000093048.6
ENSMUST00000093046.6
ENSMUST00000064019.8
ENSMUST00000102682.4
Tom1l2
target of myb1-like 2 (chicken)
chr12_+_8674224 1.05 ENSMUST00000111122.2
Pum2
pumilio 2 (Drosophila)
chr11_-_98149551 1.00 ENSMUST00000103143.3
Fbxl20
F-box and leucine-rich repeat protein 20
chr9_+_5345414 0.98 ENSMUST00000027009.4
Casp12
caspase 12
chr1_+_53313636 0.92 ENSMUST00000114484.1
Osgepl1
O-sialoglycoprotein endopeptidase-like 1
chr1_+_53313622 0.90 ENSMUST00000027265.3
Osgepl1
O-sialoglycoprotein endopeptidase-like 1
chr17_+_8311101 0.86 ENSMUST00000154553.1
Sft2d1
SFT2 domain containing 1
chr7_-_45136391 0.78 ENSMUST00000146760.1
Flt3l
FMS-like tyrosine kinase 3 ligand
chr2_+_105904629 0.77 ENSMUST00000037499.5
Immp1l
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr12_+_8674129 0.73 ENSMUST00000111123.2
ENSMUST00000178015.1
ENSMUST00000020915.3
Pum2
pumilio 2 (Drosophila)
chr12_-_119238794 0.73 ENSMUST00000026360.8
Itgb8
integrin beta 8
chr7_-_29906524 0.69 ENSMUST00000159920.1
ENSMUST00000162592.1
Zfp27
zinc finger protein 27
chr1_-_191164815 0.68 ENSMUST00000171798.1
Fam71a
family with sequence similarity 71, member A
chr18_-_39487096 0.67 ENSMUST00000097592.2
ENSMUST00000115571.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr13_+_40704005 0.67 ENSMUST00000069457.1
Gm9979
predicted gene 9979
chr1_-_79761752 0.65 ENSMUST00000113512.1
ENSMUST00000113513.1
ENSMUST00000113515.1
ENSMUST00000113514.1
ENSMUST00000113510.1
ENSMUST00000113511.1
ENSMUST00000048820.7
Wdfy1
WD repeat and FYVE domain containing 1
chr9_+_5345450 0.63 ENSMUST00000151332.1
Casp12
caspase 12
chr16_+_36875119 0.62 ENSMUST00000135406.1
ENSMUST00000114812.1
ENSMUST00000134616.1
ENSMUST00000023534.6
Golgb1
Golgb1
golgi autoantigen, golgin subfamily b, macrogolgin 1
golgi autoantigen, golgin subfamily b, macrogolgin 1
chr8_+_91070052 0.61 ENSMUST00000034091.7
Rbl2
retinoblastoma-like 2
chr9_+_107580117 0.61 ENSMUST00000093785.4
Nat6
N-acetyltransferase 6
chr8_+_105170668 0.60 ENSMUST00000109395.1
ENSMUST00000109394.1
ENSMUST00000052209.2
ENSMUST00000109392.1
Cbfb
core binding factor beta
chr7_-_45136102 0.59 ENSMUST00000125500.1
Flt3l
FMS-like tyrosine kinase 3 ligand
chr4_+_155451570 0.58 ENSMUST00000135407.1
ENSMUST00000105619.1
C030017K20Rik
RIKEN cDNA C030017K20 gene
chr15_-_10470490 0.57 ENSMUST00000136591.1
Dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr2_-_105904484 0.56 ENSMUST00000122965.1
Elp4
elongation protein 4 homolog (S. cerevisiae)
chr14_-_32201869 0.55 ENSMUST00000170331.1
ENSMUST00000013845.6
Timm23
translocase of inner mitochondrial membrane 23
chr6_+_86365673 0.54 ENSMUST00000071492.7
Fam136a
family with sequence similarity 136, member A
chr15_+_85735564 0.54 ENSMUST00000109423.1
Ppara
peroxisome proliferator activated receptor alpha
chr11_-_75454656 0.53 ENSMUST00000173320.1
Wdr81
WD repeat domain 81
chr13_+_100108155 0.52 ENSMUST00000129014.1
Serf1
small EDRK-rich factor 1
chr9_-_107605295 0.51 ENSMUST00000102529.3
Sema3b
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr7_+_46396439 0.51 ENSMUST00000025202.6
Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr10_-_71285234 0.48 ENSMUST00000020085.6
Ube2d1
ubiquitin-conjugating enzyme E2D 1
chr6_-_42461017 0.46 ENSMUST00000090156.1
Olfr458
olfactory receptor 458
chr10_+_80148263 0.42 ENSMUST00000099492.3
ENSMUST00000042057.5
Midn
midnolin
chr7_-_45136056 0.42 ENSMUST00000130628.1
Flt3l
FMS-like tyrosine kinase 3 ligand
chr13_-_95250166 0.41 ENSMUST00000162153.1
ENSMUST00000160957.2
ENSMUST00000159598.1
ENSMUST00000162412.1
Pde8b
phosphodiesterase 8B
chr11_-_6065538 0.40 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
Camk2b
calcium/calmodulin-dependent protein kinase II, beta
chr1_+_43092588 0.39 ENSMUST00000039080.3
8430432A02Rik
RIKEN cDNA 8430432A02 gene
chr11_-_73199013 0.37 ENSMUST00000006103.2
ENSMUST00000108476.1
Ctns
cystinosis, nephropathic
chr7_+_29519158 0.32 ENSMUST00000141713.1
4932431P20Rik
RIKEN cDNA 4932431P20 gene
chrX_+_73503074 0.30 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
Atp2b3
ATPase, Ca++ transporting, plasma membrane 3
chr2_+_181864337 0.29 ENSMUST00000039551.8
Polr3k
polymerase (RNA) III (DNA directed) polypeptide K
chr11_+_116918844 0.28 ENSMUST00000103027.3
Mgat5b
mannoside acetylglucosaminyltransferase 5, isoenzyme B
chr13_+_100107997 0.28 ENSMUST00000142155.1
ENSMUST00000022145.8
ENSMUST00000132053.1
Serf1
small EDRK-rich factor 1
chr8_-_13254096 0.25 ENSMUST00000171619.1
Adprhl1
ADP-ribosylhydrolase like 1
chr10_+_52388963 0.25 ENSMUST00000160539.1
Nepn
nephrocan
chr15_-_83251720 0.24 ENSMUST00000164614.1
ENSMUST00000049530.6
A4galt
alpha 1,4-galactosyltransferase
chr17_+_24696234 0.22 ENSMUST00000019464.7
Noxo1
NADPH oxidase organizer 1
chr16_-_36874806 0.15 ENSMUST00000075946.5
Eaf2
ELL associated factor 2
chr8_-_13254068 0.14 ENSMUST00000168498.1
Adprhl1
ADP-ribosylhydrolase like 1
chr2_+_48814109 0.13 ENSMUST00000063886.3
Acvr2a
activin receptor IIA
chr13_+_8202922 0.12 ENSMUST00000123187.1
Adarb2
adenosine deaminase, RNA-specific, B2
chr13_-_100108337 0.11 ENSMUST00000180822.1
BC001981
cDNA sequence BC001981
chr4_-_156234777 0.10 ENSMUST00000105569.3
Klhl17
kelch-like 17
chr13_+_8202860 0.08 ENSMUST00000064473.6
Adarb2
adenosine deaminase, RNA-specific, B2
chrX_+_7657260 0.08 ENSMUST00000033485.7
Prickle3
prickle homolog 3 (Drosophila)
chr17_-_32788284 0.06 ENSMUST00000159086.2
Zfp871
zinc finger protein 871
chr6_+_6863769 0.04 ENSMUST00000031768.6
Dlx6
distal-less homeobox 6
chr7_+_4922251 0.03 ENSMUST00000047309.5
Nat14
N-acetyltransferase 14
chrX_+_93286499 0.00 ENSMUST00000046565.7
ENSMUST00000113947.2
Arx
aristaless related homeobox
chr7_-_44997535 0.00 ENSMUST00000124232.1
ENSMUST00000003290.4
Bcl2l12
BCL2-like 12 (proline rich)

Network of associatons between targets according to the STRING database.

First level regulatory network of Gcm1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.3 GO:0006069 ethanol oxidation(GO:0006069)
1.0 6.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.5 1.9 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.5 1.8 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.4 1.7 GO:0015744 succinate transport(GO:0015744)
0.4 2.0 GO:0015886 heme transport(GO:0015886)
0.4 1.2 GO:0007172 signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.3 1.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.3 1.1 GO:0045358 negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.2 2.0 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.2 1.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 1.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 1.8 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 0.4 GO:0060466 activation of meiosis involved in egg activation(GO:0060466)
0.1 0.7 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 2.7 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 1.3 GO:0060406 positive regulation of penile erection(GO:0060406)
0.1 0.4 GO:0015811 L-cystine transport(GO:0015811)
0.1 1.6 GO:0097264 self proteolysis(GO:0097264)
0.1 0.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.5 GO:0072363 regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072363)
0.1 1.1 GO:0097421 liver regeneration(GO:0097421)
0.1 0.5 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 1.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.4 GO:0035106 operant conditioning(GO:0035106)
0.1 1.5 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.3 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.6 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1 0.4 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.5 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.2 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.7 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0046881 sperm ejaculation(GO:0042713) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.5 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 5.7 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 1.5 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 1.1 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 1.5 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.1 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.6 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 1.0 GO:0001662 behavioral fear response(GO:0001662)
0.0 0.3 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.6 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.3 0.8 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.4 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 1.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 4.5 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 1.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.5 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 2.0 GO:0072562 blood microparticle(GO:0072562)
0.0 0.5 GO:0008305 integrin complex(GO:0008305)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.2 GO:0032587 ruffle membrane(GO:0032587)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.3 6.3 GO:0004925 prolactin receptor activity(GO:0004925)
0.7 2.0 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.6 1.8 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.6 7.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.6 1.7 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.5 2.0 GO:0015232 heme transporter activity(GO:0015232)
0.4 1.3 GO:0031686 uridine nucleotide receptor activity(GO:0015065) A1 adenosine receptor binding(GO:0031686) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.3 1.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 5.7 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 1.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.7 GO:0038051 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.4 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 1.6 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1 0.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 2.7 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.6 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 1.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.6 GO:0015266 protein channel activity(GO:0015266)
0.0 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.0 1.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.9 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.1 GO:0030276 clathrin binding(GO:0030276)
0.0 0.4 GO:0043274 phospholipase binding(GO:0043274)
0.0 1.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 1.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 5.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 6.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 1.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.0 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.5 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 1.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation